CN1121417A - Pearl oyster preparation for supplement of calcium - Google Patents
Pearl oyster preparation for supplement of calcium Download PDFInfo
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- CN1121417A CN1121417A CN95100154A CN95100154A CN1121417A CN 1121417 A CN1121417 A CN 1121417A CN 95100154 A CN95100154 A CN 95100154A CN 95100154 A CN95100154 A CN 95100154A CN 1121417 A CN1121417 A CN 1121417A
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Abstract
A kind of Chinese proprietary preparation uses pearl powder, mother-of-pearl powder, oyster powder, amber powder and abalone shell powder as raw materials, which are activated by field. It can be made into capsule, powder and oral liquor. It features acidic neutral, palatable and calcium and effective components are easy to be absorbed by human body and has the functions of tonifying the kidney, strengthening bone, softening the blood vessel, accelerating healing fracture, curing and preventing osteoporosis and neurasthenia.
Description
The present invention relates to the health medicine of made from pure-natural marine living-things, being specially with Margarita, Concha Ostreae, Concha Margaritifera is the Chinese medicine preparation of replenishing the calcium of Main Ingredients and Appearance.
Existing Chinese medicine calcium-supplementing preparation, as " activated calcium ", how " SHENGU JIAONANG ", " Gai Tianli ", " strong male electuary " etc. are primary raw material with single Concha Ostreae or Margarita powder, perhaps are equipped with capsule, electuary or pill etc. that other bone meal etc. is processed into.These calcium-supplementing preparation alkalescence are strong, the pH value height, and after many people take, stomach sense discomfort, loss of appetite.As " SHENGU JIAONANG ", pH value is obeyed the back great quantity of water drinking more than 10, and stomach is still felt bad, and makes the people forbidding, is reluctant to obey again.And institute's calcic poorly soluble wherein, being difficult for being absorbed by the body, calcium absorptivity is low, so effect of supplemented calcium is undesirable.Be difficult to reach the effect for the treatment of or preventing some disease.
Purpose of the present invention, excavating Chinese pools of traditional Chinese medicine, on the basis of Margarita ball, be primary raw material with natural marine Margarita, Concha Ostreae, Concha Margaritifera, improve prescription, adopt modern science and technology and special technology, develop a kind of neutral meta-acid, mouthfeel is suitable, institute's calcic and effective ingredient, be easily absorbed by the body, the dosage form of conveniently taking has treatment and the calcium supplement health care preparation of the double effects that keeps healthy.
Natural marine organism: Margarita, Concha Margaritifera, Concha Ostreae etc., contain multiple constant and the trace element and the several amino acids nutritional labeling such as calcium, phosphorus, iodine, potassium, magnesium, copper, manganese, ferrum, zinc, germanium, selenium of human body needs, wherein calcium content is especially abundant.So calcium supplement health care medicine of the present invention, the raw material of selecting for use is natural Margarita, Concha Margaritifera, Concha Ostreae, succinum, Concha Haliotidis, Ootheca Mantidis, Carapax Trionycis.The Concha Ostreae and the Concha Haliotidis that will wherein be alkalescence before the preparation carry out acidification, and with in the medicine composition, each raw material carries out activation processing under magnetic field, make its structural arrangement ordering, to increase the wherein dissolubility of effective ingredient, is easily absorbed by the body.The Chinese medicine preparation of forming by the activatory marine natural product in field of the present invention, the composition of its pharmacological activation (weight) is:
Margarita powder (activation) 3-30%
Concha Margaritifera powder (activation) 25～60%
Acidify Concha Ostreae powder (activation) 25～60%
Succinum powder (activation) 0.2～4%
Acidify Concha Haliotidis powder (activation) 0.1～1.5%
Ootheca Mantidis powder (activation) 0.1～1%
Turtle ' s carapace powder (activation) 0.1～3% described acidification is meant the Concha Ostreae after the high-temperature calcination, Concha Haliotidis, soaks 1-5 hour Concha Ostreae, Concha Haliotidis in the common tablet vinegar of one times of dilute with water.Described pharmacological activation is meant that through magnetic field intensity be 0.5-5 hour medicated powder of activation under 600-2500 Gauss's the condition, can reach activation effect.Pearl oyster preparation for supplement of calcium of the present invention, the best of field pharmacological activation is formed (weight): Margarita powder (activation) 8%, Concha Margaritifera powder (activation) 54%, acidify Concha Ostreae powder (activation) 35%, Succinum powder (activation) 0.5%, acidify Concha Haliotidis powder (activation) 1.0%, Ootheca Mantidis powder (activation) 1.0%, turtle ' s carapace powder (activation) 0.5%.
Pearl oyster of the present invention replenish the calcium Chinese medicine preparation to add the duty processing step as follows:
1, selected, the cleaning of raw material, pulverizing and pretreatment
(1) Margarita: selected (nothing is gone mouldy, nothing is rotted, free from insect pests)-clean (with 30 ℃ of-40 ℃ of clear water)-airing (room temperature)-(150-2500 order)-sterilization-encapsulation-magnetic field of pulverize-sieving activate-to store for future use.
(2) Concha Margaritifera: selected (nothing is gone mouldy, nothing is rotted, free from insect pests) once clean (clean after 1 hour with 80 ℃ alkaline soaks, the reuse flushing with clean water totally-secondary cleaning (soak with ethanol with 70% 30 minutes)-airing (room temperature)-(the 150-2500 order)-sterilization-encapsulation-magnetic field of pulverize-sieving activate-stores for future use.
(3) Concha Ostreae: selected (nothing is gone mouldy, nothing is rotted, free from insect pests, no sedimentation)-clean (80 ℃ alkaline soak was cleaned after 1 hour) water flushing-calcining (1000 ℃-1300 ℃/24 hours)-select again burns shortcake and high-quality product-acidify that nothing is mingled with-leave standstill, filter (removing precipitated impurities)-dry 100 ℃-120 ℃/3-8 hour)-pulverize-sieving, (150-2500 order)-encapsulation-magnetic field activate-stores for future use.
(4) succinum: selected (nothing is gone mouldy, free from insect pests)-water cleans (room temperature)-airing-(the 150-2500 order)-sterilization-encapsulation-magnetic field of pulverize-sieving and activate-stores for future use.
(5) Concha Haliotidis: selected (nothing is gone mouldy, nothing is rotted, free from insect pests, no sedimentation)-clean (alkaline soak use flushing with clean water after half an hour)-calcine (800 ℃-1000 ℃/24 hours)-acidify-oven dry (100 ℃-120 ℃/3 hours)-(150-2500 order) encapsulation-magnetic field of sieving activate-stores for future use.
(6) Ootheca Mantidis: (30 ℃ of-40 ℃ of water)-pulverize-sieving, (150-2500 order)-encapsulation-magnetic field activate-stores for future use selected (nothing is gone mouldy, nothing is rotted, free from insect pests)-clean.
(7) Carapax Trionycis: selected (nothing is gone mouldy, nothing is rotted, free from insect pests) cleans (with 80 ℃ of alkaline soaks after 20 minutes, water flushing)-soak with ethanol of reuse 70% pulls-airing (room temperature)-pulverize-sieve (150-2500 order)-sterilization-encapsulation-magnetic field out and activate-stores for future use after 20 minutes.
Described aqueous alkali refers to that all adding 10 fens tap waters with edible alkali (sodium carbonate) 1 minute (weight) is mixed with; Described water for cleaning all refers to tap water; Encapsulation is meant with bag activatory powder raw material is distributed into bag (being 1kg as every bag) in a small amount, seals then tightly, to prevent moisture absorption and air admission.Sterilising conditions is generally 100 ℃-120 ℃/3-5 hour.70% ethanol is meant that adding water with 95% edible ethanol blends and form.The magnetic field activating apparatus is to have the general electromagnetic field equipment that magnetic field intensity is 600-2500 Gauss.
The preparation of 2 medicines and mixing
Ratio of components by said medicine takes by weighing each raw material through 1 selected processing activated processing, mixes, and makes its abundant mixing, detects by quality standard then.
3 are made into different dosage form
(1) capsule (encapsulated) technological process
Prepare before the worker by (cleaning means, get the raw materials ready)-dress before quality inspection (calcium content, PH, moisture, health examination)-fill-quality inspection (content uniformity, calcium content: 60 ± 10mg/0.21g)-polishing-quality inspection (moisture, antibacterial)-cover bubble-quality inspection (comprehensive quality inspection)-magnetic field activation-packing.
(2) electuary
With mixed powder and an amount of thickening agent, flavoring agent mix homogeneously-quality inspection, granulation-quality inspection (calcium content: 200 ± 10mg/5g)-drying-granulate-quality inspection (moisture, pH value calcium content, health examination)-packing-quality inspection (200 ± 10mg/ bag)-magnetic field activation-outer package.
(3) oral liquid
Acidify mixed powder-survey calcium amount-add lactic acid (25-80% of TC)-with monosodium glutamate (5-25% that adds total calcium content)-leave standstill-get supernatant-mother solution-with flavoring agent and water (6-10 deionized water doubly)-detect (calcium content)-fill (calcium content: 50 ± 10mg/10ml)-sterilization-complete detection.
Described flavoring agent is meant citric acid, malic acid, Mel, stevioside, Radix Asparagi sugar, white sugar etc., and adding adjuvant total amount is advisable with the 1-3% of total liquid measure.
Quality inspection content in described capsule, electuary, the oral liquid processing technology is all undertaken by attached relevant capsule of appendix of in 1994 negative of People's Republic of China's medicine, electuary, oral liquid regulation with method.
Pearl oyster preparation for supplement of calcium of the present invention, the pharmacodynamic feature of collection Margarita, Concha Ostreae, neutral meta-acid, mouthfeel is suitable, and calcium and effective ingredient are easy to absorb, and conveniently take.Show through clinical taking: have the kidney invigorating bone strengthening, vessel softening, accelerating union of bone fracture, control person in middle and old age osteoporosis; The arresting convulsion of calming the nerves, allaying tiredness, convulsion, control neurasthenia and insomnia; The key body is replenished the calcium, and it is short long to increase intelligence, control children's rickets; Moistening skin beautifying is eliminated mottle, and senile plaque strengthens skin elasticity, the effect of slow down aging.Therefore be a kind of health medicine with treatment and health care double effects.
Example 1
1, the preparation before the raw material processing:
(1) selected nothing go mouldy, do not have rot, the Margarita of free from insect pests, Concha Margaritifera, each 10kg of Concha Ostreae, do not have the succinum, Concha Haliotidis (no sedimentation), the Ootheca Mantidis that go mouldy, have rotten, free from insect pests, each 0.5kg is standby for Carapax Trionycis;
(2) take by weighing the 1kg edible alkali and add the 10kg tap water, be made into the aqueous alkali of dilution.
(3) get tablet vinegar 1000ml and add the 1000ml tap water, be made into the tablet vinegar solution for standby of dilution;
(4) (the beneficial nutritional preparation in Wenchang, Hainan ten thousand factory produces the electromagnetic field activating apparatus, specification: magnetic field intensity: 600-2500 Gauss).
2, raw material processing, acidify, activation
(1) Margarita, Ootheca Mantidis are used 30 ℃-40 ℃ tap water respectively, cleaned up, behind the room temperature airing, pulverize with wind energy conversion system, cross 200 purposes sieve, sterilized 3 hours for 100 ℃, packaged with plastic bag, activate in electromagnetic field, (field intensity 600-2500 Gauss, soak time 3 hours) is standby.
(2) with Concha Margaritifera with the edible alkaline soak of 80 ℃ dilution after 1 hour, clean, clean with the tap water flushing, the soak with ethanol of reuse 70% 30 minutes, the room temperature airing, pulverize with the wind-force pulverizer, cross 200 mesh sieves, sterilized 3 hours for 100 ℃, encapsulate with plastic bag, carry out the field activation, field intensity 600-2500 Gauss, soak time 3 hours.
(3) Concha Ostreae is cleaned after 1 hour with 80 ℃ of alkaline soaks, with the tap water flushing, then, 1200 ℃ of calcinings 24 hours, select and burn the high-quality product that crisp nothing is mingled with, carry out acidify (with the tablet vinegar solution soaking of dilution 2 hours), filter, dried 4 hours for 80 ℃-100 ℃, pulverize, cross 200 mesh sieves, sterilize, get the acidify Concha Ostreae powder, with the activation of marching into the arena after the plastic bag encapsulation, field intensity 600-2500 Gauss activates 3 hours.
(4) succinum is cleaned, airing, pulverizing, cross 200 mesh sieves, sterilization, the condition activation of marching into the arena as hereinbefore.
(5) Concha Haliotidis is cleaned with edible alkaline soak backlash half an hour of diluting, 1000 ℃ of calcinings are after 24 hours, and the same method with the acidify of tablet vinegar solution liquid, was dried 4 hours for 80-100 ℃.Cross 200 mesh sieves, sterilize, get the acidify Concha Haliotidis, activate standby by an identical field activation condition.
(6) with Carapax Trionycis with 80 ℃ edible alkaline soak 20 minutes, clean with the tap water flushing, the soak with ethanol with 70% 20 minutes is pulled out, pulverize behind the room temperature airing, reach 200 mesh sieves, sterilized 3 hours for 100 ℃, with plastic bag encapsulation, condition same as described above, activation is 3 hours in magnetic field.
Example 2
Take by weighing the processing activated raw material in (1) (2) (3) (4) (5) (6) that example 1 is made: Margarita powder 21.5g, Concha Margaritifera powder 193g, acidify Concha Ostreae powder 212g, Succinum powder 1.5g, acidify Concha Haliotidis powder 0.8g, Ootheca Mantidis powder 0.4g, turtle ' s carapace powder 0.5g mix homogeneously is made into hybrid medicine again.Through magnetic field activation, test rating standard up to specification: calcium content is 30 ± 10%, PH6-8, moisture＜3% hygiology index.Encapsulated 2000 altogether, every calcic 60 ± 10mg/0.21g, pH value 6-8, moisture＜3%, the hygiology index is qualified.
Example 3
Take by weighing the activatory raw material that example 1 is made: Margarita powder 22.05g, Concha Margaritifera powder 47.25g, acidify Concha Ostreae powder 32.55g, Succinum powder 0.5g, acidify Concha Haliotidis powder 0.84g, Ootheca Mantidis powder 1.05g, turtle ' s carapace powder 0.73g is made into mixed powder, checks whole indexs qualified: calcium content is 30 ± 10%, PH6-8, moisture＜3% hygiology index.Encapsulated 500 altogether, every is closed calcium amount 60 ± 10mg/0.21g, and pH value is 6-8, moisture＜3%, and the hygiology index is qualified.
Example 4
Taking by weighing example 1 has processed and an activatory raw material: Margarita powder 16g, Concha Margaritifera 108g, acidify Concha Ostreae 70g, succinum 1g, acidify Concha Haliotidis 2g, Ootheca Mantidis 2g, Carapax Trionycis 1g is made into mixed powder, detection, calcium content 60 ± 10mg/0.21g, pH value 6-8, moisture＜3%, the hygiology index is qualified.
Example 5
(1) the mixed powder 45g for the treatment of excess syndrome example 4, with adding 140ml water towards the vinegar solution soaking of rare 140ml tablet vinegar after 5 hours, mensurations calcium content is 50mg/ml, adding lactic acid 12.5ml, monosodium glutamate 5g leaves standstill, and gets supernatant, obtains mother solution, and the survey calcium content is 35mg/ml.
(2) take by weighing citric acid 2g, malic acid 1.2g, Mel 20ml, stevioside 2g, Radix Asparagi sugar 1g,, white sugar 10g in the 1800ml deionized water, after dissolving, filter, decontamination, aqueous solution that leaches and the above-mentioned mother solution 280ml mix homogeneously that makes, the survey calcium content is 5mg/ml.
(3) press the 50mg/10ml fill, and 100 ℃ of sterilizations 45 minutes, to carry out complete detection up to specification.
(4) in magnetic field intensity 600-2500 Gauss's magnetic field, activate 3 hours, make oral liquid.
Example 6
(1) the mixed powder 17g for the treatment of excess syndrome example 3;
(2) use citric acid 22g, malic acid 0.2, aspartic acid 4g, white sugar 30g mix homogeneously is made into flavoring agent 36.4g;
(3) use carrageenan 2g, cyclodextrin 40g, dextrin 25g, sodium carboxymethyl cellulose 2g mix homogeneously; (1) (2) (3) mix homogeneously is made electuary through quality inspection *-granulation-quality inspection (calcium content)-drying-granulate-quality inspection (moisture, calcium content, PH, hygiology index)-packing (calcium content 200mg/5g)-quality inspection comprehensively-magnetic field activation-outer package.
Annotate: the raw material powder of medicine, finished product, all quality are analysed survey and are all measured by requirement, the method for 1990 editions, one appendix defineds of People's Republic of China's distiller.
Claims (5)
1, a kind of medicine of replenishing the calcium is characterized in that the Chinese medicine preparation be made up of the activatory marine natural product in field, and the composition (weight) of described pharmacological activation is:
Margarita powder 3-30%
Concha Margaritifera powder 25-60%
Acidify Concha Ostreae powder 25-60%
Succinum powder 0.2-4%
Acidify Concha Haliotidis powder 0.1-1.5%
Ootheca Mantidis powder 0.1-1%
Described pharmacological activation of turtle ' s carapace powder 0.1-3%, be meant that through magnetic field intensity be 0.5-5 hour medicated powder of activation under the 600-2500 Gauss condition, described acidify Concha Ostreae powder, acidify Concha Haliotidis powder all refer to 1-5 hour the medicated powder of tablet vinegar solution soaking through one times of water dilution.
2, the medicine of replenishing the calcium as claimed in claim 1 is characterized in that the best composition (weight) of described pharmacological activation is:
Margarita powder 8%
Concha Margaritifera powder 54%
Acidify Concha Ostreae powder 35%
Succinum powder 0.5%
Acidify Concha Haliotidis powder 1.0%
Ootheca Mantidis powder 1.0%
Turtle ' s carapace powder 0.5%
3, the medicine of replenishing the calcium as claimed in claim 1 is characterized in that described Chinese medicine preparation, the capsule formulation of being made up of described pharmacological activation.
4, the medicine of replenishing the calcium as claimed in claim 1 is characterized in that described Chinese medicine preparation, is to add an amount of flavoring agent and the electuary dosage form of thickening agent by described pharmacological activation.
5, the medicine of replenishing the calcium as claimed in claim 1 is characterized in that described Chinese medicine preparation, is the lactic acid that is added the 25-80% (weight) of its total calcium content by described pharmacological activation, the oral liquid of the monosodium glutamate of 5-25% (weight) and 6-10 deionized water doubly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN95100154A CN1067248C (en) | 1995-01-27 | 1995-01-27 | Pearl oyster preparation for supplement of calcium |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN95100154A CN1067248C (en) | 1995-01-27 | 1995-01-27 | Pearl oyster preparation for supplement of calcium |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1121417A true CN1121417A (en) | 1996-05-01 |
| CN1067248C CN1067248C (en) | 2001-06-20 |
Family
ID=5073278
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN95100154A Expired - Fee Related CN1067248C (en) | 1995-01-27 | 1995-01-27 | Pearl oyster preparation for supplement of calcium |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1067248C (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2785503A1 (en) * | 1998-11-06 | 2000-05-12 | Pharma Futura | Aragonite orthorhombic calcium carbonate from mother of pearl is used to make foods for the prevention and treatment of osteoporosis |
| WO2001084963A1 (en) * | 2000-05-11 | 2001-11-15 | Pharma Futura | Edible composition containing micronised nacre powder |
| CN102166286A (en) * | 2011-04-25 | 2011-08-31 | 李秋荣 | Medicine for treating osteoporosis |
| CN103750333A (en) * | 2014-02-19 | 2014-04-30 | 北京高平技术开发有限公司 | Composite weight-losing health product and preparing method thereof |
| CN110038033A (en) * | 2019-05-30 | 2019-07-23 | 王心武 | A kind of preparation method of kidney invigorating and bone strengthening medicine |
| CN110973638A (en) * | 2019-11-26 | 2020-04-10 | 康道生物（南通）有限公司 | Crystal-bonded capsule and manufacturing process thereof |
| CN113018400A (en) * | 2021-04-02 | 2021-06-25 | 曹三强 | Bagged foot recuperation rehabilitation medicinal powder |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1058528A (en) * | 1990-12-27 | 1992-02-12 | 江西省农业科普服务部 | The manufacture method of Ca-N separation pearl cream (having another name called the coquelicot pearl nourishing cream) |
| CN1071578A (en) * | 1991-10-17 | 1993-05-05 | 顾月甫 | The preparation method of natural biological calcium |
-
1995
- 1995-01-27 CN CN95100154A patent/CN1067248C/en not_active Expired - Fee Related
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2785503A1 (en) * | 1998-11-06 | 2000-05-12 | Pharma Futura | Aragonite orthorhombic calcium carbonate from mother of pearl is used to make foods for the prevention and treatment of osteoporosis |
| WO2001084963A1 (en) * | 2000-05-11 | 2001-11-15 | Pharma Futura | Edible composition containing micronised nacre powder |
| FR2808657A1 (en) * | 2000-05-11 | 2001-11-16 | Pharma Futura | Edible composition containing micronized nacre powder of specific particle size, as high bioavailability calcium supplement for promoting osteogenesis in humans or animals |
| CN102166286A (en) * | 2011-04-25 | 2011-08-31 | 李秋荣 | Medicine for treating osteoporosis |
| CN102166286B (en) * | 2011-04-25 | 2012-05-30 | 阎树昕 | Medicine for treating osteoporosis |
| CN103750333A (en) * | 2014-02-19 | 2014-04-30 | 北京高平技术开发有限公司 | Composite weight-losing health product and preparing method thereof |
| CN103750333B (en) * | 2014-02-19 | 2016-09-07 | 北京高平技术开发有限公司 | A kind of compound slimming health product and preparation method thereof |
| CN110038033A (en) * | 2019-05-30 | 2019-07-23 | 王心武 | A kind of preparation method of kidney invigorating and bone strengthening medicine |
| CN110973638A (en) * | 2019-11-26 | 2020-04-10 | 康道生物（南通）有限公司 | Crystal-bonded capsule and manufacturing process thereof |
| CN113018400A (en) * | 2021-04-02 | 2021-06-25 | 曹三强 | Bagged foot recuperation rehabilitation medicinal powder |
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| Publication number | Publication date |
|---|---|
| CN1067248C (en) | 2001-06-20 |
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