CN1121235C - Medicine for treating osteoporosis and its preparing process - Google Patents

Medicine for treating osteoporosis and its preparing process Download PDF

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Publication number
CN1121235C
CN1121235C CN99119660A CN99119660A CN1121235C CN 1121235 C CN1121235 C CN 1121235C CN 99119660 A CN99119660 A CN 99119660A CN 99119660 A CN99119660 A CN 99119660A CN 1121235 C CN1121235 C CN 1121235C
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China
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medicine
radix
herba taxilli
powder
parts
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Expired - Fee Related
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CN99119660A
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CN1289616A (en
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王旭时
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Individual
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Individual
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Abstract

The present invention discloses a medicine for treating osteoporosis and a preparation method. The medicine can be made into watered pills, capsules, medicinal powder or honeyed pills through special technology by using Radix Codonopsis, Radix Notoginseng, Chinese taxillus twig, malaytea scurfpea fruit, prepared rhizome of rehmannia and snow frog fat as raw materials. The medicine of the present invention has the advantages of less medicinal odour, wide medicinal source, new technology, low cost, convenient taking and conspicuous and exact curative effect, and is easy for patients to accept.

Description

Treat osteoporotic medicine and preparation method thereof
The present invention relates to the osteoporotic medicine of a kind of treatment, is the Chinese patent medicine of feedstock production with the Chinese herbal medicine specifically, the invention still further relates to the preparation method of this medicine.
Osteoporosis is a kind of physiological degeneration, and very big to the infringement of health, the clinical onset rate is very high.Many clinically old fracture or hyperplastic spondylitis with lumbar and back pain, fracture, unknown cause are gone to a doctor, age is many between 35-55 year, serious hyperosteogeny visible patient's osteoporosis degree on the X-ray sheet is the very high diseases of disability rate than big mostly of actual age.
Both at home and abroad to the primary disease Drug therapy, run into following stubborn problem at present:
1, Chinese medicine class:
Bone curing capsule, the bone recovering particles etc. that relaxes of healing, effect is not fairly obvious and cause abdominal distention, stomachache and loose stool.
2, Western medicine class:
Tridin, Allan sodium phosphate sheet, ipriflavone etc., side effect is very big, the vomiting that causes nausea, erythra, can not take pregnant person.
The object of the present invention is to provide a kind of benefiting QI for activating blood circulation effect that has, again the kidney invigorating and do not grow greasy, the not impairment of YIN of invigorating blood circulation, strong because of gasifying, the prosperous and Chinese Traditional Medicines of sclerotin heavily fortified point of metabolism.
Another object of the present invention provides the preparation method of these Chinese Traditional Medicines.
Solution of the present invention is based on understanding and the Therapeutic Principle of motherland's medical science to osteoporosis and diseases induced mechanism, achieve with reference to modern pharmacological research, according to the theory of kidney governing bones with chemistry is said and activating blood circulation to dissipate blood stasis and dredge the collateral analgesic theory, from motherland's medicine treasure-house, the screening Chinese prescription, several times prescription is adjusted and the dosage form improvement again, and carry out Comparison of therapeutic with LIUWEI DIHUANG WAN, Cortex torricelliae tiliifoliae, 'Qiangjin Zhuanggu ' pill and simple calcium preparation and prove superiority and curative effect that these Chinese Traditional Medicines have other drug not possess.
These Chinese Traditional Medicines flavour of a drug are few, the medicine source is wide, technology is new, workable, long shelf-life, taking convenience, and patient is easy to accept determined curative effect.
Medicine of the present invention is to be made by following bulk drugs:
Radix Codonopsis 1-30 part Fructus Psoraleae 3-40 part Radix Notoginseng 1-30 part
Radix Rehmanniae Preparata 2-40 part oviductus ranae 7-20 part Herba Taxilli 6-90 part
The crude drug preferred weight ratio range of preparation medicine of the present invention is:
Radix Codonopsis 20-30 part Fructus Psoraleae 30-40 part Radix Notoginseng 20-30 part
Radix Rehmanniae Preparata 30-40 divides oviductus ranae 8-15 part Herba Taxilli 60-90 part
The crude drug optimum weight proportioning of medicine of the present invention is:
25 parts of 35 portions of Radix Notoginseng of 25 parts of Fructus Psoraleaes of Radix Codonopsis
70 parts of 10 parts of Herba Taxillis of 35 parts of oviductus ranaes of Radix Rehmanniae Preparata
The preparation method that above-mentioned each crude drug is made medicine of the present invention is:
1, the Herba Taxilli defoliation is cleaned, with warm water soaking 8 hours, was decocted 30 minutes, the pressurization extracting juice must the Herba Taxilli decocting liquid in container, stores standby;
2, Radix Codonopsis, Radix Notoginseng, Fructus Psoraleae, the clean oven dry with oviductus ranae of Radix Rehmanniae Preparata are ground into powder;
3,2 gained medicated powder are put in the blender, poured into the Herba Taxilli decocting liquid and stir as the mud shape;
4, with watered pill machine 3 gained are processed into the watered pill, go into after the watered pill was dried in the shade 12 hours after planning machine scrapes, the oven dry packing promptly gets the watered pill of medicine of the present invention.
As with after the oven dry of gained Herba Taxilli decocting liquid, make granule or powder, also can be made into powder, capsule or honeyed pill.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, to select pure natural medical for use be raw material in the present invention, and each component meets the pharmaceutical control law regulation, and is nontoxic to human body;
2, the present invention need not decoct, no bitterness sense, and taking convenience is easy to patient and accepts;
3, flavour of a drug of the present invention are few, the medicine source is wide, technology is new, cost is low.
For showing the therapeutic effect of medicine of the present invention, the inventor uses clinical drug treatment osteoporosis case of the present invention people more than 3800 from nineteen eighty-three, with 14 days be 1 course of treatment, take 5 the course of treatment above person's 300 examples, enter the complete observation case.Among the 300 routine patients, the age minimum is 35 years old, is 72 years old to the maximum, 53.5 years old mean age, male's 188 examples wherein, women's 122 examples, pain symptom is alleviated 21 examples, pain symptom 279 examples that disappear, slight bow-backed normal 3 examples of recovering, clinical symptoms are 80 examples of development more not, union of fracture 17 examples, spinal fracture 10 examples that heal, above-mentioned case clinical symptoms all is eased, and X-ray sheet check bone density increases.Effective percentage 100% by statistics, obvious effective rate 96.6%.
Instructions of taking:
Watered pill 0.5g/ grain is obeyed 20 at every turn, every day 2 times;
Powder 5g/ bag is obeyed 1 bag, every day 2 times at every turn;
Capsule 0.5g/ grain is obeyed the 6-8 grain at every turn, every day 3 times;
Honeyed pill 6g/ ball is obeyed a ball at every turn, every day 3 times.
Embodiment:
Take by weighing raw material by following proportioning:
Radix Codonopsis 200g Fructus Psoraleae 300g Radix Notoginseng 200g
Radix Rehmanniae Preparata 300g Herba Taxilli 600g oviductus ranae 200g
Production method is as follows:
1,600g Herba Taxilli defoliation is cleaned,, was decocted 30 minutes with decocting for Chinese herbal medicine extraction machine with warm water soaking 8 hours, the pressurization extracting juice in container, the Herba Taxilli decocting liquid is stored standby;
2,200g Radix Codonopsis, 200g Radix Notoginseng, 300g Fructus Psoraleae, the clean oven dry with the 200g oviductus ranae of 300g Radix Rehmanniae Preparata are ground into powder;
3,2 gained medicated powder are put in the blender, poured into 1 gained Herba Taxilli decocting liquid and stir as the mud shape;
4, with watered pill machine 3 gained are processed into the watered pill of 12 mm dias, go into the planning machine back oven dry of scraping after the watered pill was dried in the shade 12 hours, promptly get the medicine watered pill of the present invention.

Claims (6)

1, the osteoporotic medicine of a kind of treatment, the active ingredient that it is characterized in that it is to be made by following bulk drugs:
Radix Codonopsis 1-30 part Fructus Psoraleae 3-40 part Radix Notoginseng 1-30 part
Radix Rehmanniae Preparata 2-40 part oviductus ranae 7-20 part Herba Taxilli 6-90 part
2, the osteoporotic medicine of treatment according to claim 1 is characterized in that the weight proportion for preparing each used crude drug of its active ingredient is:
Radix Codonopsis 20-30 part Fructus Psoraleae 30-40 part Radix Notoginseng 20-30 part
Radix Rehmanniae Preparata 30-40 part oviductus ranae 8-15 part Herba Taxilli 60-90 part
3, the osteoporotic medicine of treatment according to claim 1 is characterized in that the weight proportion for preparing each used raw material of its active ingredient is:
25 parts of 35 portions of Radix Notoginseng of 25 parts of Fructus Psoraleaes of Radix Codonopsis
70 parts of 10 parts of Herba Taxillis of 35 parts of oviductus ranaes of Radix Rehmanniae Preparata
4,, it is characterized in that its dosage form can be the watered pill, powder, capsule or honeyed pill according to claim 1, the osteoporotic medicine of 2 or 3 described treatments.
5, the preparation method of the osteoporotic medicine of treatment as claimed in claim 1 is characterized in that preparation method is as follows:
(1) the Herba Taxilli leave is cleaned, with warm water soaking 8 hours, was decocted 30 minutes, the pressurization extracting juice must the Herba Taxilli decocting liquid in container, stores standby;
(2) Radix Codonopsis, Radix Notoginseng, Fructus Psoraleae, the clean oven dry with oviductus ranae of Radix Rehmanniae Preparata are ground into powder;
(3) (2) gained medicated powder is put in the blender, poured into the Herba Taxilli decocting liquid and stir as the mud shape;
(4) with watered pill machine (3) gained is processed into the watered pill, goes into after the watered pill was dried in the shade 12 hours after planning machine scrapes, the oven dry packing promptly gets the watered pill of medicine of the present invention.
6, the preparation method of the osteoporotic medicine of treatment according to claim 5 is characterized in that: also can make granule or powder with after the oven dry of Herba Taxilli decocting liquid, make powder, capsule or honeyed pill.
CN99119660A 1999-09-24 1999-09-24 Medicine for treating osteoporosis and its preparing process Expired - Fee Related CN1121235C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN99119660A CN1121235C (en) 1999-09-24 1999-09-24 Medicine for treating osteoporosis and its preparing process

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN99119660A CN1121235C (en) 1999-09-24 1999-09-24 Medicine for treating osteoporosis and its preparing process

Publications (2)

Publication Number Publication Date
CN1289616A CN1289616A (en) 2001-04-04
CN1121235C true CN1121235C (en) 2003-09-17

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN99119660A Expired - Fee Related CN1121235C (en) 1999-09-24 1999-09-24 Medicine for treating osteoporosis and its preparing process

Country Status (1)

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