CN112121122A - Dendrobium huoshanense compound preparation - Google Patents

Dendrobium huoshanense compound preparation Download PDF

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Publication number
CN112121122A
CN112121122A CN202011028428.9A CN202011028428A CN112121122A CN 112121122 A CN112121122 A CN 112121122A CN 202011028428 A CN202011028428 A CN 202011028428A CN 112121122 A CN112121122 A CN 112121122A
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CN
China
Prior art keywords
dendrobium huoshanense
compound preparation
dendrobium
huoshanense
maltose
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Pending
Application number
CN202011028428.9A
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Chinese (zh)
Inventor
祝文兴
唐珂
刘新利
谢华
潘华章
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Huoshan Xianhu Baicao Biotechnology Co ltd
Qilu University of Technology
Original Assignee
Huoshan Xianhu Baicao Biotechnology Co ltd
Qilu University of Technology
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Priority to CN202011028428.9A priority Critical patent/CN112121122A/en
Publication of CN112121122A publication Critical patent/CN112121122A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8984Dendrobium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/488Pueraria (kudzu)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The invention discloses a dendrobium huoshanense compound preparation which is prepared from dendrobium huoshanense, mulberry, red date, liquorice, medlar, maltose, kudzu root, American ginseng and hawthorn. Compared with the prior art, the dendrobium huoshanense and various body-building medicines are combined, and are kneaded, de-enzymed and fermented, so that the medicinal value of the dendrobium huoshanense is well developed, the dendrobium huoshanense and other medicines are scientifically proportioned, and the dendrobium huoshanense sweet compound preparation is prepared with maltose, is favorable for taking, has good taste, has good pharmacological action on a human body, and has popularization and application values.

Description

Dendrobium huoshanense compound preparation
Technical Field
The invention relates to the technical field of medicines, and particularly relates to a dendrobium huoshanense compound preparation.
Background
Dendrobium huoshanense, also called as Dendrobium huoshanense, is the best product of Dendrobium nobile and is a rare medicinal material which is endangered to be extinct in China. Its dried stem and fresh dendron can be used as both of them. Dendrobe is sweet and neutral and has no toxicity. The traditional Chinese medicine composition is mainly used for treating injuries in middle and large-jiao deficiency, eliminating arthralgia to descend qi, tonifying internal organs, wasting, strengthening yin, replenishing vital essence, nourishing intestines and stomach for a long time, tonifying interior, calming stomach qi, growing muscles, dispelling evil heat miliaria qi, and treating pain, cold and weak arthralgia of feet and knees. Calm the mind, remove fright, lighten the body, prolong life, tonify qi, remove heat, treat weak waist and feet and strengthen yang of men. Expelling wind arthralgia of skin, long-term cold in bones, tonifying kidney, strengthening bones and muscles, warming water, benefiting intelligence, clearing qi, treating fever, spontaneous perspiration, carbuncle, cellulitis and pus discharge. In the prior art, dendrobium huoshanense is mostly harvested and dried, and thus the dendrobium huoshanense cannot be well developed in medicinal value, so that an improvement space exists.
Disclosure of Invention
The invention aims to solve the problems and provide a dendrobium huoshanense compound preparation.
The invention realizes the purpose through the following technical scheme:
the invention is prepared from dendrobium huoshanense, mulberry, red date, liquorice, medlar, maltose, kudzu root, American ginseng and hawthorn.
Furthermore, each part of the health-care beverage comprises, by weight, 40-50% of dendrobium huoshanense, 10-20% of mulberry, 2-5% of red date, 1-4% of liquorice, 4-8% of medlar, 8-12% of maltose, 5-10% of kudzu root, 4-6% of American ginseng and 5-8% of hawthorn.
Preferably, each part of the health-care beverage comprises 45% of dendrobium huoshanense, 15% of mulberry, 4% of red date, 2% of liquorice, 5% of medlar, 10% of maltose, 9% of kudzuvine root, 4% of American ginseng and 6% of hawthorn by weight.
Specifically, the preparation method of the dendrobium huoshanense compound preparation comprises the following steps:
s1: collecting fresh dendrobium huoshanense leaves, cleaning and selecting complete fresh leaves for later use;
s2: putting the fresh dendrobium huoshanense leaves into a hot pot, heating, rolling and deactivating enzyme;
s3: putting fresh mulberries into the deactivated dendrobium huoshanense for repeated rolling and tanning to form clusters and standing for 4 hours;
s4: pulverizing fructus Jujubae, Glycyrrhrizae radix, fructus Lycii, radix Puerariae, radix Panacis Quinquefolii, and fructus crataegi;
s5: fully mixing the mixture obtained in the step S4 with the mixture obtained in the step S3, and drying;
s6: grinding the dried crushed material, and screening the ground material by a 80-mesh screen for later use;
s7: and (4) mixing maltose with the powder ground in the step S6, pressing the mixture into tablets or granules after mixing, and preparing the dendrobium huoshanense compound preparation.
Preferably, the deactivation temperature in the step S2 is 160-180 ℃. The drying step in the step S5 is performed at a temperature of 80 to 100 ℃.
The invention has the beneficial effects that:
compared with the prior art, the dendrobium huoshanense compound preparation disclosed by the invention is prepared by combining dendrobium huoshanense with various medicines for strengthening the body and kneading, deactivating enzymes and fermenting, so that the medicinal value of dendrobium huoshanense is well developed, the dendrobium huoshanense compound preparation is scientifically matched with other medicines, and the dendrobium huoshanense compound preparation is prepared with maltose into a sweet compound preparation, is beneficial to taking, has good taste, has good pharmacological action on a human body, and has popularization and application values.
Detailed Description
The invention is further illustrated below:
the invention is prepared from dendrobium huoshanense, mulberry, red date, liquorice, medlar, maltose, kudzu root, American ginseng and hawthorn.
Furthermore, each part of the health-care beverage comprises, by weight, 40-50% of dendrobium huoshanense, 10-20% of mulberry, 2-5% of red date, 1-4% of liquorice, 4-8% of medlar, 8-12% of maltose, 5-10% of kudzu root, 4-6% of American ginseng and 5-8% of hawthorn.
Preferably, each part of the health-care beverage comprises 45% of dendrobium huoshanense, 15% of mulberry, 4% of red date, 2% of liquorice, 5% of medlar, 10% of maltose, 9% of kudzuvine root, 4% of American ginseng and 6% of hawthorn by weight.
Specifically, the preparation method of the dendrobium huoshanense compound preparation comprises the following steps:
s1: collecting fresh dendrobium huoshanense leaves, cleaning and selecting complete fresh leaves for later use;
s2: putting the fresh dendrobium huoshanense leaves into a hot pot, heating, rolling and deactivating enzyme;
s3: putting fresh mulberries into the deactivated dendrobium huoshanense for repeated rolling and tanning to form clusters and standing for 4 hours;
s4: pulverizing fructus Jujubae, Glycyrrhrizae radix, fructus Lycii, radix Puerariae, radix Panacis Quinquefolii, and fructus crataegi;
s5: fully mixing the mixture obtained in the step S4 with the mixture obtained in the step S3, and drying;
s6: grinding the dried crushed material, and screening the ground material by a 80-mesh screen for later use;
s7: and (4) mixing maltose with the powder ground in the step S6, pressing the mixture into tablets or granules after mixing, and preparing the dendrobium huoshanense compound preparation.
Preferably, the deactivation temperature in the step S2 is 160-180 ℃. The drying step in the step S5 is performed at a temperature of 80 to 100 ℃.
The foregoing shows and describes the general principles and features of the present invention, together with the advantages thereof. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (6)

1. A dendrobium huoshanense compound preparation is characterized in that: is prepared from dendrobium huoshanense, mulberry, red date, liquorice, medlar, maltose, kudzu root, American ginseng and hawthorn.
2. The dendrobium huoshanense compound preparation as claimed in claim 1, characterized in that: according to the weight ratio, each part of the dendrobium huoshanense tea comprises 40-50% of dendrobium huoshanense, 10-20% of mulberry, 2-5% of red dates, 1-4% of liquorice, 4-8% of medlar, 8-12% of maltose, 5-10% of kudzu vine roots, 4-6% of American ginseng and 5-8% of hawthorn.
3. The dendrobium huoshanense compound preparation as claimed in claim 2, characterized in that: according to the weight ratio, each part contains 45% of dendrobium huoshanense, 15% of mulberry, 4% of red date, 2% of liquorice, 5% of medlar, 10% of maltose, 9% of kudzuvine root, 4% of American ginseng and 6% of hawthorn.
4. The dendrobium huoshanense compound preparation according to claim 3, which is characterized in that: the preparation method of the dendrobium huoshanense compound preparation comprises the following steps:
s1: collecting fresh dendrobium huoshanense leaves, cleaning and selecting complete fresh leaves for later use;
s2: putting the fresh dendrobium huoshanense leaves into a hot pot, heating, rolling and deactivating enzyme;
s3: putting fresh mulberries into the deactivated dendrobium huoshanense for repeated rolling and tanning to form clusters and standing for 4 hours;
s4: pulverizing fructus Jujubae, Glycyrrhrizae radix, fructus Lycii, radix Puerariae, radix Panacis Quinquefolii, and fructus crataegi;
s5: fully mixing the mixture obtained in the step S4 with the mixture obtained in the step S3, and drying;
s6: grinding the dried crushed material, and screening the ground material by a 80-mesh screen for later use;
s7: and (4) mixing maltose with the powder ground in the step S6, pressing the mixture into tablets or granules after mixing, and preparing the dendrobium huoshanense compound preparation.
5. The dendrobium huoshanense compound preparation according to claim 4, which is characterized in that: the deactivation temperature in the step S2 is 160-180 ℃.
6. The dendrobium huoshanense compound preparation according to claim 4, which is characterized in that: the drying step in the step S5 is performed at a temperature of 80 to 100 ℃.
CN202011028428.9A 2020-09-26 2020-09-26 Dendrobium huoshanense compound preparation Pending CN112121122A (en)

Priority Applications (1)

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CN202011028428.9A CN112121122A (en) 2020-09-26 2020-09-26 Dendrobium huoshanense compound preparation

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Application Number Priority Date Filing Date Title
CN202011028428.9A CN112121122A (en) 2020-09-26 2020-09-26 Dendrobium huoshanense compound preparation

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CN112121122A true CN112121122A (en) 2020-12-25

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113080455A (en) * 2021-05-10 2021-07-09 皖西学院 Dendrobium huoshanense and red ginseng oral liquid as well as preparation process and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102266491A (en) * 2011-07-15 2011-12-07 安徽圣农生物科技股份有限公司 Formula of compound dendrobium huoshanense extract and production process thereof
CN102266490A (en) * 2011-07-15 2011-12-07 安徽圣农生物科技股份有限公司 Formula of compound dendrobium huoshanense granules and production method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102266491A (en) * 2011-07-15 2011-12-07 安徽圣农生物科技股份有限公司 Formula of compound dendrobium huoshanense extract and production process thereof
CN102266490A (en) * 2011-07-15 2011-12-07 安徽圣农生物科技股份有限公司 Formula of compound dendrobium huoshanense granules and production method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
胡艳辉等: "霍山石斛颗粒小鼠免疫调节作用研究", 《毒理学杂志》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113080455A (en) * 2021-05-10 2021-07-09 皖西学院 Dendrobium huoshanense and red ginseng oral liquid as well as preparation process and application thereof

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Application publication date: 20201225