CN112121090A - Formula for treating hyperplastic scars and preparation process - Google Patents

Formula for treating hyperplastic scars and preparation process Download PDF

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Publication number
CN112121090A
CN112121090A CN201910493512.9A CN201910493512A CN112121090A CN 112121090 A CN112121090 A CN 112121090A CN 201910493512 A CN201910493512 A CN 201910493512A CN 112121090 A CN112121090 A CN 112121090A
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CN
China
Prior art keywords
vaseline
medicine
radix sophorae
sophorae flavescentis
fructus cnidii
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201910493512.9A
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Chinese (zh)
Inventor
车艳红
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Shanxi Meishi Biotechnology Co ltd
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Shanxi Meishi Biotechnology Co ltd
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Publication date
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Priority to CN201910493512.9A priority Critical patent/CN112121090A/en
Publication of CN112121090A publication Critical patent/CN112121090A/en
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489—Sophora, e.g. necklacepod or mamani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/55—Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/646—Arachnids, e.g. spiders, scorpions, ticks or mites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13—Coniferophyta (gymnosperms)
    • A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/234—Cnidium (snowparsley)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/35—Extraction with lipophilic solvents, e.g. Hexane or petrol ether

Abstract

The invention discloses a formula for treating hypertrophic scars and a preparation process thereof, relating to the technical field of traditional Chinese medicines and comprising the following traditional Chinese medicines and additive components: vaseline, radix Sophorae Flavescentis, fructus Cnidii, cortex pseudolaricis, processed Scorpio, Carthami flos, artificial Moschus, fructus Bruceae, and semen Persicae; processing various traditional Chinese medicine raw materials, adding cold sesame oil, decocting with slow fire until the medicine turns golden yellow, removing the medicine, adding pills, taking out the medicine when the sesame oil is nearly black, adding vaseline into the medicine liquid, stirring uniformly, and making into plaster for use; can quickly and efficiently soften scar tissues, promote metabolism, eliminate scars and relieve the pain of patients.

Description

Formula for treating hyperplastic scars and preparation process
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a formula for treating hypertrophic scars and a preparation process thereof.
Background
The pathological tissue difference of the hyperplastic scar and the normal scar is only the thickening of collagen fibers at the deep part of the scar, and the hyperplastic scar and the normal scar are in irregular arrangement, or in a wave shape, or are wound into a rope shape; the hyperplastic scar is mostly generated after the healing of a deep burn wound, a reticular proliferative scar is also common at the suture position around a skin sheet after the skin grafting of a III-degree burn wound, in addition, most common is an incision scar after the suture of any incision, and the hyperplastic scar is represented as a prominent surface, irregular appearance, uneven height, flush hyperemia, solid and tough quality, causalgia and pruritus, and brings great pain to the physiology and the psychology of a patient; the existing methods for treating hyperplastic scars have obvious effect such as dermabrasion, fat injection, chemical dermabrasion and punching and cutting, but the treatment process is long, patients suffer great pain, the operation difficulty is high, certain risk is caused, and the treatment success rate is low.
Disclosure of Invention
The invention aims to solve the technical problem of providing a formula for treating hypertrophic scars, which can relieve itching and pain and has no repeated hyperplasia and complication, and a preparation process thereof.
The technical scheme of the invention is as follows: the formula for treating hypertrophic scars comprises the following components in parts by weight: 500 g of vaseline, 80 g of radix sophorae flavescentis, 120 g of fructus cnidii, 80 g of pseudolarix, 200 g of roasted scorpion, 60 g of safflower, 3 g of artificial musk, 95 g of brucea javanica and 70 g of peach kernel.
The preparation process of a formula for treating hypertrophic scars comprises the following steps: firstly, weighing 80 g of radix sophorae flavescentis, 120 g of fructus cnidii, 80 g of pseudolarix, 200 g of scorpion, 60 g of safflower, 3 g of artificial musk, 95 g of brucea javanica and 70 g of peach kernel, and processing by classification; the second step is that: putting processed radix Sophorae Flavescentis, fructus Cnidii, cortex pseudolaricis, processed Scorpio, Carthami flos, Moschus, fructus Bruceae, and semen Persicae together in cold oleum Sesami, decocting the cold oleum Sesami just over the medicinal materials with slow fire until the medicinal materials become golden yellow, removing the medicinal materials, adding Plumbum Preparatium, taking out the medicinal materials when the oleum Sesami is nearly black, and keeping the medicinal liquid; the third step: and adding 500 g of vaseline into the liquid medicine obtained in the step, uniformly stirring, and preparing into a plaster for use.
The invention has the beneficial effects that: the ointment has quick effect on treating hyperplastic scars and surgical scars caused by scalds, is beneficial to dredging sweat glands, promoting blood circulation to remove blood stasis and regenerating epidermis, has no toxic or side effect, can quickly and efficiently soften scar tissues, promotes metabolism, eliminates scars and greatly relieves the pain of patients.
Detailed Description
The pharmacological effects of the invention are:
vaseline: the skin care cream is stable in property, not easy to deteriorate, free of irritation and not easy to cause sensitivity of a human body, can form a film on the surface of the skin after being smeared on the skin, enables water not to be evaporated and dissipated easily, can keep the skin in a wet state, prevents bacteria in the air from contacting with the skin, and reduces the possibility of infection, and is commonly used as a raw material of medicines and cosmetics.
Flavescent sophora root: bitter taste and cold nature, which is in the channels of heart, liver, stomach, large intestine and bladder, and can be used for treating dysentery, hematochezia, jaundice anuresis, leucorrhea with reddish discharge, vulva swelling and pruritus vulvae, eczema, skin pruritus, scabies, tinea, leprosy and trichomonas vaginitis.
Fructus cnidii: bitter taste and warm nature, entering kidney channel, eliminating dampness, dispelling pathogenic wind, killing parasites, warming kidney and tonifying yang, and can be used for treating sexual impotence, cold womb, leukorrhagia due to cold-dampness, and lumbago due to damp arthralgia; it can be used for treating vulval eczema and trichomonal vaginitis.
And (3) pseudolarix: pungent and bitter in flavor, warm in nature, entering spleen meridian, dispelling pathogenic wind and removing dampness, and can be used for killing parasites, relieving itching, scabies, tinea, eczema and neurodermatitis.
Scorpion: sweet and pungent in flavor, neutral in nature, dispelling pathogenic wind, relieving convulsion, and removing toxic substance, and can be used for treating rubella, apoplexy, hemiplegia, facial distortion, aphasia, and tetany.
Safflower: pungent taste and warm nature, enter heart and liver meridians, activate blood and dredge meridian, remove blood stasis and relieve pain, and can be used for treating coronary heart disease, traumatic injury, blood stasis and swelling and pain.
Artificial musk: can be used for treating fever unconsciousness, apoplexy with phlegm syncope, qi stagnation with sudden syncope, central aversion to coma, heart and abdomen pain, pain and swelling, scrofula, sore throat, and traumatic injury.
Brucea javanica: bitter taste and cold nature, belongs to large intestine and liver channels, has the effects of clearing away heat and toxic materials and stopping dysentery, is used for treating dysentery and malaria, and externally treats wart and helosis.
Peach kernel: bitter and sweet in taste, neutral in nature, enter heart, liver and large intestine channels, activate blood circulation to dissipate blood stasis, relax bowel, relieve cough and asthma, and are used for amenorrhea and dysmenorrhea, abdominal mass and mass, lung abscess and intestinal abscess, traumatic injury, intestinal dryness and constipation, cough and asthma.
The formula for treating hypertrophic scars comprises the following components in parts by weight: 500 g of vaseline, 80 g of radix sophorae flavescentis, 120 g of fructus cnidii, 80 g of pseudolarix, 200 g of roasted scorpion, 60 g of safflower, 3 g of artificial musk, 95 g of brucea javanica and 70 g of peach kernel.
The preparation process of a formula for treating hypertrophic scars comprises the following steps: firstly, weighing 80 g of radix sophorae flavescentis, 120 g of fructus cnidii, 80 g of pseudolarix, 200 g of scorpion, 60 g of safflower, 3 g of artificial musk, 95 g of brucea javanica and 70 g of peach kernel, and processing by classification; the second step is that: putting processed radix Sophorae Flavescentis, fructus Cnidii, cortex pseudolaricis, processed Scorpio, Carthami flos, Moschus, fructus Bruceae, and semen Persicae together in cold oleum Sesami, decocting the cold oleum Sesami just over the medicinal materials with slow fire until the medicinal materials become golden yellow, removing the medicinal materials, adding Plumbum Preparatium, taking out the medicinal materials when the oleum Sesami is nearly black, and keeping the medicinal liquid; the third step: and adding 500 g of vaseline into the liquid medicine obtained in the step, uniformly stirring, and preparing into a plaster for use.
The above embodiments are only for illustrating the technical solutions of the present invention and not for limiting, and it should be understood by those skilled in the art that modifications or equivalent substitutions can be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention, and all of them should be covered in the claims of the present invention.

Claims (2)

1. A prescription for treating hyperplastic scars and a preparation process thereof, the prescription comprises vaseline, radix sophorae flavescentis, fructus cnidii, cortex pseudolaricis, roasted scorpion, safflower, artificial musk, brucea javanica and peach kernel, and is characterized in that: the formula comprises the following components in parts by weight: 500 g of vaseline, 80 g of radix sophorae flavescentis, 120 g of fructus cnidii, 80 g of pseudolarix, 200 g of roasted scorpion, 60 g of safflower, 3 g of artificial musk, 95 g of brucea javanica and 70 g of peach kernel.
2. The formulation and process for the treatment of hypertrophic scars as claimed in claim 1, wherein: the preparation process flow of the formula for treating the hyperplastic scar is as follows: firstly, weighing 80 g of radix sophorae flavescentis, 120 g of fructus cnidii, 80 g of pseudolarix, 200 g of scorpion, 60 g of safflower, 3 g of artificial musk, 95 g of brucea javanica and 70 g of peach kernel, and processing by classification; the second step is that: putting processed radix Sophorae Flavescentis, fructus Cnidii, cortex pseudolaricis, processed Scorpio, Carthami flos, Moschus, fructus Bruceae, and semen Persicae together in cold oleum Sesami, decocting the cold oleum Sesami just over the medicinal materials with slow fire until the medicinal materials become golden yellow, removing the medicinal materials, adding Plumbum Preparatium, taking out the medicinal materials when the oleum Sesami is nearly black, and keeping the medicinal liquid; the third step: and adding 500 g of vaseline into the liquid medicine obtained in the step, uniformly stirring, and preparing into a plaster for use.
CN201910493512.9A 2019-06-06 2019-06-06 Formula for treating hyperplastic scars and preparation process Pending CN112121090A (en)

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CN201910493512.9A CN112121090A (en) 2019-06-06 2019-06-06 Formula for treating hyperplastic scars and preparation process

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1054372A (en) * 1991-01-24 1991-09-11 衡阳市郊区湘江医院 A kind of manufacture method of tincture for curing scar
CN102579920A (en) * 2012-03-27 2012-07-18 郑州密丽药业有限公司 Chinese medicine ointment for curing human-body scars and preparation method thereof
CN105920254A (en) * 2016-06-27 2016-09-07 王青年 Hypertrophic scar eliminating reducing liquid

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1054372A (en) * 1991-01-24 1991-09-11 衡阳市郊区湘江医院 A kind of manufacture method of tincture for curing scar
CN102579920A (en) * 2012-03-27 2012-07-18 郑州密丽药业有限公司 Chinese medicine ointment for curing human-body scars and preparation method thereof
CN105920254A (en) * 2016-06-27 2016-09-07 王青年 Hypertrophic scar eliminating reducing liquid

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
李学巧: "弹力绷带固定疤痕灵膏外敷治疗瘢痕疗效观察", 《中医正骨》 *

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Application publication date: 20201225