CN112120017A - Nano slow-release gel bactericide and preparation method thereof - Google Patents
Nano slow-release gel bactericide and preparation method thereof Download PDFInfo
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- CN112120017A CN112120017A CN202010777548.2A CN202010777548A CN112120017A CN 112120017 A CN112120017 A CN 112120017A CN 202010777548 A CN202010777548 A CN 202010777548A CN 112120017 A CN112120017 A CN 112120017A
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- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 24
- 239000003899 bactericide agent Substances 0.000 title claims abstract description 23
- 238000002360 preparation method Methods 0.000 title abstract description 6
- OSVXSBDYLRYLIG-UHFFFAOYSA-N dioxidochlorine(.) Chemical compound O=Cl=O OSVXSBDYLRYLIG-UHFFFAOYSA-N 0.000 claims abstract description 134
- 239000004155 Chlorine dioxide Substances 0.000 claims abstract description 67
- 235000019398 chlorine dioxide Nutrition 0.000 claims abstract description 67
- 239000000126 substance Substances 0.000 claims abstract description 27
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims abstract description 25
- 229910052799 carbon Inorganic materials 0.000 claims abstract description 25
- 238000013268 sustained release Methods 0.000 claims abstract description 24
- 239000012730 sustained-release form Substances 0.000 claims abstract description 24
- 229920001223 polyethylene glycol Polymers 0.000 claims abstract description 21
- 239000002243 precursor Substances 0.000 claims abstract description 20
- 230000002378 acidificating effect Effects 0.000 claims abstract description 19
- 239000002103 nanocoating Substances 0.000 claims abstract description 18
- 239000000463 material Substances 0.000 claims abstract description 17
- 239000002202 Polyethylene glycol Substances 0.000 claims abstract description 14
- 239000011248 coating agent Substances 0.000 claims abstract description 12
- 238000000576 coating method Methods 0.000 claims abstract description 12
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 30
- 238000007581 slurry coating method Methods 0.000 claims description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- 239000011347 resin Substances 0.000 claims description 11
- 229920005989 resin Polymers 0.000 claims description 11
- UKLNMMHNWFDKNT-UHFFFAOYSA-M sodium chlorite Chemical group [Na+].[O-]Cl=O UKLNMMHNWFDKNT-UHFFFAOYSA-M 0.000 claims description 11
- 229960002218 sodium chlorite Drugs 0.000 claims description 11
- 235000015165 citric acid Nutrition 0.000 claims description 10
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 claims description 9
- 239000004925 Acrylic resin Substances 0.000 claims description 8
- 238000002156 mixing Methods 0.000 claims description 8
- 229920001661 Chitosan Polymers 0.000 claims description 7
- 239000004705 High-molecular-weight polyethylene Substances 0.000 claims description 7
- 229920001030 Polyethylene Glycol 4000 Polymers 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 7
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 6
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 6
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 claims description 6
- 230000005284 excitation Effects 0.000 claims description 6
- 239000011268 mixed slurry Substances 0.000 claims description 6
- 229920002523 polyethylene Glycol 1000 Polymers 0.000 claims description 6
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims description 3
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims description 3
- 239000002250 absorbent Substances 0.000 claims description 3
- 235000011167 hydrochloric acid Nutrition 0.000 claims description 3
- 235000006408 oxalic acid Nutrition 0.000 claims description 3
- 239000011975 tartaric acid Substances 0.000 claims description 3
- 235000002906 tartaric acid Nutrition 0.000 claims description 3
- 239000002253 acid Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 11
- 230000001954 sterilising effect Effects 0.000 abstract description 8
- 239000000645 desinfectant Substances 0.000 abstract description 6
- 238000005507 spraying Methods 0.000 abstract description 4
- 239000000499 gel Substances 0.000 description 51
- 238000004659 sterilization and disinfection Methods 0.000 description 9
- 238000003756 stirring Methods 0.000 description 7
- 239000008367 deionised water Substances 0.000 description 5
- 229910021641 deionized water Inorganic materials 0.000 description 5
- 230000000052 comparative effect Effects 0.000 description 4
- 238000004806 packaging method and process Methods 0.000 description 4
- 238000007789 sealing Methods 0.000 description 4
- 241000894006 Bacteria Species 0.000 description 3
- 239000007789 gas Substances 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 241000700605 Viruses Species 0.000 description 2
- 230000003115 biocidal effect Effects 0.000 description 2
- 239000003139 biocide Substances 0.000 description 2
- 230000002035 prolonged effect Effects 0.000 description 2
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical class ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 description 1
- 241000711573 Coronaviridae Species 0.000 description 1
- 241000195493 Cryptophyta Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 239000011247 coating layer Substances 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002070 germicidal effect Effects 0.000 description 1
- QWPPOHNGKGFGJK-UHFFFAOYSA-N hypochlorous acid Chemical compound ClO QWPPOHNGKGFGJK-UHFFFAOYSA-N 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 231100000956 nontoxicity Toxicity 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 238000001243 protein synthesis Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 230000014616 translation Effects 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
- A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Dentistry (AREA)
- Environmental Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Agronomy & Crop Science (AREA)
- Wood Science & Technology (AREA)
- Toxicology (AREA)
- Dispersion Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Disinfection, Sterilisation Or Deodorisation Of Air (AREA)
Abstract
The invention provides a nano slow-release gel bactericide and a preparation method thereof. The nano slow-release gel bactericide comprises independent chlorine dioxide slow-release gel and an acid-excited slow-release ball; the chlorine dioxide slow-release gel comprises a carbon-based nano coating structure and a slow-release gel body; the carbon-based nano coating structure comprises a chlorine dioxide precursor substance and a carbon-based nano coating material for coating the chlorine dioxide precursor substance; the acid-excited sustained-release ball comprises low-molecular-weight polyethylene glycol and an acidic substance. The nano slow-release gel bactericide can greatly prolong the service time, has excellent slow-release effect and sterilizing effect, and is suitable for various places which are not suitable for spraying a disinfectant in a large area.
Description
Technical Field
The invention relates to a bactericide, in particular to a slow-release gel bactericide and a preparation method thereof.
Background
Chlorine dioxide (ClO)2) Is a gas from yellow green to orange yellow, and is a safe and nontoxic green disinfectant which is internationally recognized. The sterilizing performance of chlorine dioxide is that it can release nascent oxygen and hypochlorous acid molecule when it contacts with microbe, and has good adsorptivity and penetrability to microbe cell, and can effectively oxidize the enzyme containing sulfur radical in cell, destroy enzyme system and make amino acid in protein oxidatively decomposeThe microbial protein synthesis is quickly controlled, the effect of inhibiting the growth or killing bacteria is achieved, the effects of killing spores, viruses, algae, fungi, iron-blood bacteria, sulfate reducing bacteria and the like are well achieved, and the effects of completely having no influence on the cell structures of higher animals are achieved.
With the outbreak of new coronavirus in the early 2020, the disinfection and sterilization become normal. The large-scale spraying of alcohol and 84 disinfectants has a limited action range and cannot kill all viruses in the environment. It can only act on the surface of an object for a short time, and can not meet the time required by disinfection, and the disinfection effect can not be achieved. Meanwhile, alcohol, 84 disinfectant and the like can bring potential safety hazards. The chlorine dioxide has good disinfection effect and no toxicity to human bodies, and is the first choice for disinfection. Because the chlorine dioxide has active chemical property and is not stable, although the chlorine dioxide aqueous solution which is not easy to volatilize and decompose is prepared, the release period of the activated liquid chlorine dioxide is short, and the transportation, the storage and the use are inconvenient.
Therefore, there is an urgent need for a sterilizing product that is not harmful to the human body and can maintain the sterilizing effect continuously.
Disclosure of Invention
In view of the above, the main object of the present invention is to provide a nano sustained-release gel that is harmless to human body and can continuously sterilize, and the slow release of reactive chlorine dioxide is realized by nano slurry-coating technology, so as to achieve the purpose of continuous sterilization.
According to one aspect of the invention, a nano slow-release gel bactericide is provided, which comprises independent chlorine dioxide slow-release gel and an acid-excited slow-release ball;
the chlorine dioxide slow-release gel comprises a carbon-based nano coating structure and a slow-release gel body;
the carbon-based nano coating structure comprises a chlorine dioxide precursor substance and a carbon-based nano coating material for coating the chlorine dioxide precursor substance;
the acid-excited sustained-release ball comprises low-molecular-weight polyethylene glycol and an acidic substance.
Preferably, the chlorine dioxide slow-release gel and the acid-excited slow-release ball are mixed in a mass ratio of 100 (1-8) before use.
Preferably, the sustained release gel comprises a polymeric water absorbent resin and a high molecular weight polyethylene glycol.
Preferably, the chlorine dioxide precursor is sodium chlorite and the acidic substance is selected from one or more of citric acid, oxalic acid, tartaric acid and hydrochloric acid.
Preferably, the carbon-based nano-slurry coating material is nano-chitosan.
Preferably, the high molecular water-absorbing resin is polyacrylic resin.
According to another aspect of the present invention, a method for preparing a nano sustained-release gel bactericide comprises the steps of:
dispersing a carbon-based nano slurry coating material in water to form a slurry coating system;
adding a chlorine dioxide precursor substance into the slurry coating system, and uniformly mixing to obtain mixed slurry;
adding high-molecular water-absorbing resin and high-molecular polyethylene glycol into the mixed slurry to form chlorine dioxide slow-release gel;
preparing the low molecular weight polyethylene glycol and acidic substances into an acidic excitation slow release ball;
the chlorine dioxide slow release gel is mixed with the acid-excited slow release ball before use.
Preferably, the high molecular weight polyethylene glycol is PEG4000 and the low molecular weight polyethylene glycol is PEG 1000.
Specifically, according to the nano slow-release gel bactericide provided by the invention, the coating layer of the carbon-based nano coating material is formed on the surface of the chlorine dioxide precursor substance, and then the gel formed by the macromolecular water-absorbent resin is formed outside the coating structure, so that the formed chlorine dioxide slow-release gel can promote the chlorine dioxide to be slowly released when being mixed with the acidic excitation slow-release ball, the using time can be greatly prolonged, the nano slow-release gel bactericide has excellent slow-release effect and sterilization effect, and is suitable for various places where large-area disinfectant spraying is not suitable.
Drawings
Further objects, features and advantages of the present invention will become apparent from the following description of embodiments of the invention, with reference to the accompanying drawings, in which:
fig. 1 shows the release profiles of the germicides according to example 1 and comparative example 1.
Detailed Description
The nano slow-release gel bactericide provided by the invention comprises independent chlorine dioxide slow-release gel and an acid-excited slow-release ball, wherein the mass ratio of the chlorine dioxide slow-release gel to the acid-excited slow-release ball is preferably 100 (1-8), and more preferably 100: 5.
The chlorine dioxide slow-release gel comprises a carbon-based nano coating structure and a slow-release gel body coating the carbon-based nano coating structure. The carbon-based nano coating structure comprises a chlorine dioxide precursor substance and a carbon-based nano coating material coating the chlorine dioxide precursor substance. The carbon-based nano-coating material can be nano-chitosan, and the average particle size of the carbon-based nano-coating material can be 0.8-1.5 nm. The chlorine dioxide precursor material may be a material that is capable of being converted to chlorine dioxide upon stimulation by an acidic material, and may be, for example, sodium chlorite.
The acid-excited slow-release ball can slowly release chlorine dioxide gas generated by converting chlorine dioxide precursor substances.
The slow release gel is formed by taking high molecular water-absorbing resin as a gel and taking high molecular weight polyethylene glycol as a stabilizer. The high molecular water-absorbing resin can be polyacrylic resin, preferably polyacrylic resin with the number average molecular weight of 8000-15000. The number average molecular weight of the high molecular weight polyethylene glycol can be 3500-4500, preferably PEG 4000.
The slow-release gel further forms a gel on the outer surface of the carbon-based nano-coating structure, so that the release speed of chlorine dioxide gas generated by the chlorine dioxide precursor substance coated in the carbon-based nano-coating structure is further delayed, and the duration of the bactericidal activity is longer.
The acid-excited slow-release ball comprises low-molecular-weight polyethylene glycol and an acidic substance. The low molecular weight polyethylene glycol may have a number average molecular weight of 800-.
The acidic substance is an acidic substance which can react with the chlorine dioxide precursor substance to generate chlorine dioxide, and can be one or more of citric acid, oxalic acid, tartaric acid and hydrochloric acid, preferably citric acid.
The chlorine dioxide sustained-release gel and the acid-activated sustained-release ball are mixed before use, preferably in a mass ratio of 100 (1-8), for example, 100: 5. Chlorine dioxide precursor species (e.g., sodium chlorite) and acidic species (e.g., citric acid) are reactants that generate gaseous chlorine dioxide at room temperature.
The invention also provides a method for preparing the nano slow-release gel bactericide, which comprises the following steps:
dispersing a carbon-based nano slurry coating material in water to form a slurry coating system;
adding a chlorine dioxide precursor substance into the slurry coating system, and uniformly mixing to obtain mixed slurry;
adding high molecular water-absorbing resin and high molecular polyethylene glycol into the mixed slurry to form chlorine dioxide slow-release gel (namely colloid to be excited);
preparing the low molecular weight polyethylene glycol and acidic substances into an acidic excitation slow release ball;
the chlorine dioxide slow-release gel is mixed with the acid-excited slow-release ball before use.
According to a specific embodiment, the gel bactericide is prepared from the following raw materials in percentage by mass: 5-8% of sodium chlorite, 3-5% of citric acid, 7-10% of high molecular water-absorbing resin, 0.5-2% of carbon-based nano-slurry-coating material, 2-5% of high molecular weight polyethylene glycol, 3-6% of low molecular weight polyethylene glycol and the balance of deionized water.
The preparation method of the nano slow-release gel bactericide is simple, namely, the acid-excited slow-release ball is placed immediately, and the prepared gel is placed at room temperature in an open manner, so that the effect of slowly releasing chlorine dioxide to sterilize air can be realized, and the service life of the bactericide can be greatly prolonged. The product has simple preparation and use methods, good chlorine dioxide slow-release effect and sterilization effect, and is suitable for various places such as offices, schools, communities, automobiles and the like which are not suitable for large-area spraying of disinfectants.
The present invention is further illustrated by the following examples, but is not limited thereto.
Example 1
Dissolving 0.8g of nano chitosan in 20g of deionized water, adding 5g of sodium chlorite, and uniformly stirring to form a nano slow-release coating system;
uniformly mixing 7g of polyacrylic resin and 3g of PEG4000 in 54g of water, adding the mixture into the nano slow-release coating system, and uniformly stirring again to form chlorine dioxide slow-release gel;
③ fully mixing 5g of citric acid and 5.2g of PEG1000 to form acidic excitation sustained-release gel balls;
fourthly, separately packaging and sealing to obtain finished products;
when in use, the acid-excited sustained-release gel ball is placed in the chlorine dioxide sustained-release gel to activate the chlorine dioxide sustained-release gel.
Example 2
Dissolving 2g of nano chitosan in 35g of deionized water, adding 8g of sodium chlorite, and uniformly stirring to form a nano slow-release coating system;
uniformly mixing 8g of polyacrylic resin and 5g of PEG4000 in 44g of water, adding the mixture into the nano slow-release coating system, and uniformly stirring again to form chlorine dioxide slow-release gel;
mixing 3g of citric acid and 3g of PEG1000 sufficiently to form acidic-excited sustained-release gel spheres;
fourthly, separately packaging and sealing to obtain finished products;
when in use, the acid-excited sustained-release gel ball is placed in the chlorine dioxide sustained-release gel to activate the chlorine dioxide sustained-release gel.
Example 3
Dissolving 1.3g of nano chitosan in 28g of deionized water, adding 6.5g of sodium chlorite, and uniformly stirring to form a nano slow-release coating system;
uniformly mixing 9g of polyacrylic resin and 4g of PEG4000 in 42.7g of water, adding the mixture into the nano slow-release coating system, and uniformly stirring again to form chlorine dioxide slow-release gel;
③ 4g of citric acid is fully mixed with 4.5g of PEG1000 to form the acidic excitation sustained-release gel ball;
fourthly, separately packaging and sealing to obtain finished products;
when in use, the acid-excited sustained-release gel ball is placed in the chlorine dioxide sustained-release gel to activate the chlorine dioxide sustained-release gel.
Comparative example 1
Adding 5g of sodium chlorite into 20g of deionized water, and uniformly stirring to form a sodium chlorite solution;
② 7g of polyacrylic resin and 3g of PEG4000 are evenly mixed in 54.8g of water, and added into the system to be evenly stirred again;
③ 5g of citric acid is fully mixed with 5.2g of PEG1000 to form the acid-excited sustained-release ball;
fourthly, separately packaging and sealing to obtain finished products;
when in use, the acid-excited slow-release ball is placed in a gel system to activate the chlorine dioxide slow-release gel.
Chlorine dioxide concentration and release time tests were performed on the chlorine dioxide sustained-release gels prepared in example 1 and comparative example 1 above, and the results are shown in fig. 1.
The test method comprises the following steps: at 5m3And detecting the concentration of chlorine dioxide in the air in the closed space.
As can be seen from fig. 1, the gel biocide according to example 1 (series 1) has a significantly longer release time and thus a longer effective time than the biocide according to comparative example 1 (series 2).
Other embodiments of the invention will be apparent to those skilled in the art from consideration of the specification and practice of the invention disclosed herein. It is intended that the specification and examples be considered as exemplary only, with a true scope and spirit of the invention being indicated by the following claims.
Claims (10)
1. The nanometer slow-release gel bactericide is characterized by comprising independent chlorine dioxide slow-release gel and an acid-excited slow-release ball;
the chlorine dioxide slow-release gel comprises a carbon-based nano coating structure and a slow-release gel body;
the carbon-based nano coating structure comprises a chlorine dioxide precursor substance and a carbon-based nano coating material for coating the chlorine dioxide precursor substance;
the acid-excited sustained-release ball comprises low-molecular-weight polyethylene glycol and an acidic substance.
2. The nano slow-release gel bactericide as claimed in claim 1, wherein the chlorine dioxide slow-release gel and the acid-activated slow-release ball are mixed in a mass ratio of 100 (1-8) before use.
3. The nano sustained-release gel bactericide according to claim 1, wherein the sustained-release gel comprises a high molecular water-absorbent resin and a high molecular weight polyethylene glycol.
4. The nano slow-release gel bactericide as claimed in claim 1, wherein the chlorine dioxide precursor is sodium chlorite, and the acidic substance is one or more selected from the group consisting of citric acid, oxalic acid, tartaric acid and hydrochloric acid.
5. The nano slow-release gel bactericide as claimed in claim 1, wherein the carbon-based nano slurry-coating material is nano chitosan.
6. The nano slow-release gel bactericide as claimed in claim 3, wherein the high molecular water-absorbing resin is polyacrylic resin.
7. A method for preparing a nano slow-release gel bactericide is characterized by comprising the following steps:
dispersing a carbon-based nano slurry coating material in water to form a slurry coating system;
adding a chlorine dioxide precursor substance into the slurry coating system, and uniformly mixing to obtain mixed slurry;
adding high-molecular water-absorbing resin and high-molecular polyethylene glycol into the mixed slurry to form chlorine dioxide slow-release gel;
preparing the low molecular weight polyethylene glycol and acidic substances into an acidic excitation slow release ball;
the chlorine dioxide slow release gel is mixed with the acid-excited slow release ball before use.
8. The method of claim 7, wherein the high molecular weight polyethylene glycol is PEG4000 and the low molecular weight polyethylene glycol is PEG 1000.
9. The method according to claim 7 or 8, wherein the carbon-based nanopaste material is a nano-chitosan.
10. The method of claim 7 or 8, wherein the chlorine dioxide precursor is sodium chlorite.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112970776A (en) * | 2021-02-04 | 2021-06-18 | 延瑞堂有限责任公司 | Low-temperature disinfectant for object surface, preparation method and application thereof |
| CN113197221A (en) * | 2021-05-14 | 2021-08-03 | 天津清科环保科技有限公司 | Sol-gel slow-release chlorine dioxide gel and preparation method thereof |
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| CN110947017A (en) * | 2019-12-11 | 2020-04-03 | 韶关学院 | Slow-release chlorine dioxide solid gel and preparation method and application thereof |
| CN111466406A (en) * | 2020-04-29 | 2020-07-31 | 北京青鸿福科技有限公司 | Contact type binary chlorine dioxide slow-release gel and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113197221A (en) * | 2021-05-14 | 2021-08-03 | 天津清科环保科技有限公司 | Sol-gel slow-release chlorine dioxide gel and preparation method thereof |
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| CN112120017B (en) | 2023-01-17 |
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