CN112106785A - Formula of nano physical composite bactericidal and bacteriostatic agent and preparation method thereof - Google Patents
Formula of nano physical composite bactericidal and bacteriostatic agent and preparation method thereof Download PDFInfo
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- CN112106785A CN112106785A CN202010945359.1A CN202010945359A CN112106785A CN 112106785 A CN112106785 A CN 112106785A CN 202010945359 A CN202010945359 A CN 202010945359A CN 112106785 A CN112106785 A CN 112106785A
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- quaternary ammonium
- ammonium salt
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- zinc oxide
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
- A01N59/16—Heavy metals; Compounds thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/12—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
Abstract
The invention relates to a formula of a nano physical composite sterilization and bacteriostat and a preparation method thereof, which comprises raw materials of nano-scale zinc oxide powder, micron-scale zinc oxide powder, a dodecyl-hexadecyl benzyl dimethyl ammonium chloride quaternary ammonium salt mixture, a chlorinated C8-C10 double-chain alkyl dimethyl quaternary ammonium salt, a brominated C8-C10 double-chain alkyl dimethyl quaternary ammonium salt, few-layer graphene and pure water. The invention has the advantages that: the product of the invention takes water as a solvent, adopts a physical principle to comprehensively sterilize inorganic nano and micron zinc oxide/silver oxide fine particles and organic quaternary ammonium salt, has rapidity close to one-time chemical disinfection and sterilization and persistence similar to silver ion sterilization and bacteriostasis, obtains zinc chloride through the reaction, and the zinc chloride is dissolved in water, cannot lose efficacy due to contact with chloride, has the characteristics of no color, no odor and no bleaching, has lower cost than silver ion sterilization, and greatly saves the cost.
Description
Technical Field
The invention relates to the technical field of sanitation, in particular to a formula of a nano physical composite sterilizing and bacteriostasis agent and a preparation method thereof.
Background
At present, most of commonly used bactericides for sterilizing objects have defects, some bactericides are one-time chemical disinfection and sterilization with strong sterilization and disinfection capacity, but the bactericides have no persistence completely, namely the bacteriostasis efficiency is poor, and the bactericides need to be sterilized again after being evaporated; the bactericide with good bacteriostatic efficiency and strong persistence has irritating smell, causes damage to body health if being inhaled by people for a long time, and has bleaching performance, so that sterilized articles fade, and the bactericide is not practical.
Disclosure of Invention
The technical problem to be solved by the invention is to solve the problems and provide a formula of a nano physical composite sterilization and bacteriostat which has no peculiar smell, can continuously inhibit bacteria and does not damage sterilized articles and a preparation method thereof.
In order to solve the technical problems, the technical scheme provided by the invention is as follows: the formula of the nano physical composite bactericidal and bacteriostatic agent comprises raw materials of nano-scale zinc oxide powder, micron-scale zinc oxide powder, a dodecyl to hexadecyl benzyl dimethyl ammonium chloride quaternary ammonium salt mixture, chlorinated C8-C10 double-chain alkyl dimethyl quaternary ammonium salt, brominated C8-C10 double-chain alkyl dimethyl quaternary ammonium salt, few-layer graphene and pure water.
The raw materials comprise, by weight, 1-4% of nano-scale zinc oxide powder, 1-2% of micron-scale zinc oxide powder, less than 4% of dodecyl to hexadecyl benzyl dimethyl ammonium chloride quaternary ammonium salt mixture, less than 2% of chlorinated C8-C10 double-chain alkyl dimethyl quaternary ammonium salt, less than 1% of brominated C8-C10 double-chain alkyl dimethyl quaternary ammonium salt, 1-3% of few-layer graphene and 90-95% of pure water.
A method for preparing a nano physical composite sterilizing and bacteriostasis agent comprises the following steps:
1) adding any one of the above formulas into pure water at normal temperature in sequence, and stirring at low speed for 120 seconds to obtain the product.
After adopting the structure, the invention has the following advantages: the product of the invention takes water as a solvent, adopts a physical principle including inorganic nano and micron zinc oxide fine particles and organic quaternary ammonium salt comprehensive sterilization, has rapidity close to one-time chemical disinfection and sterilization and persistence similar to silver ion sterilization and bacteriostasis, obtains zinc chloride through the reaction, and the zinc chloride is dissolved in water, cannot lose efficacy due to contact with chloride, has the characteristics of no color, no odor and no bleaching property, has lower cost than silver ion sterilization, and greatly saves the cost.
Detailed Description
The present invention is described in further detail below.
The formula of the nano physical composite bactericidal and bacteriostatic agent comprises raw materials of nano-scale zinc oxide powder, micron-scale zinc oxide powder, a dodecyl to hexadecyl benzyl dimethyl ammonium chloride quaternary ammonium salt mixture, chlorinated C8-C10 double-chain alkyl dimethyl quaternary ammonium salt, brominated C8-C10 double-chain alkyl dimethyl quaternary ammonium salt, few-layer graphene and pure water.
The raw materials comprise, by weight, 1-4% of nano-scale zinc oxide powder, 1-2% of micron-scale zinc oxide powder, less than 4% of dodecyl to hexadecyl benzyl dimethyl ammonium chloride quaternary ammonium salt mixture, less than 2% of chlorinated C8-C10 double-chain alkyl dimethyl quaternary ammonium salt, less than 1% of brominated C8-C10 double-chain alkyl dimethyl quaternary ammonium salt, 1-3% of few-layer graphene and 90-95% of pure water.
A method for preparing a nano physical composite sterilizing and bacteriostasis agent comprises the following steps:
1) adding any one of the above formulas into pure water at normal temperature in sequence, and stirring at low speed for 120 seconds to obtain the product.
In the specific implementation of the invention, the following steps are implemented:
2% of nano-scale zinc oxide powder, 1% of micron-scale zinc oxide powder, 3% of dodecyl to hexadecyl benzyl dimethyl ammonium chloride quaternary ammonium salt mixture, 1.45% of chlorinated C8-C10 double-chain alkyl dimethyl quaternary ammonium salt, 0.55% of brominated C8-C10 double-chain alkyl dimethyl quaternary ammonium salt, 1% of few-layer graphene and 90% of water.
Nano-sized zinc oxide powder: mainly dissolves out slow-release ions, catalyzes as auxiliary continuous bacteriostasis and sterilization,
micron-sized zinc oxide powder: mainly photocatalysis, sustained-release ion dissolution as auxiliary continuous bacteriostasis and sterilization,
the zinc oxide, whether nano-scale or micron-scale, has the functions of slow-release ion dissolution and photocatalysis. Research shows that the photocatalysis can be carried out even in the absence of light, the generation reason is that invisible light or electromagnetic waves with certain frequency replace visible light, meanwhile, the nano-scale zinc oxide particles are smaller than 50 nanometers, and the micron-scale zinc oxide particles are controlled to be between 1 and 20 micrometers.
Dodecyl to hexadecylbenzyl dimethyl ammonium chloride quaternary ammonium salt mixtures, generally consisting of 40% dodecyl benzyl dimethyl ammonium chloride, 50% tetradecyl benzyl dimethyl ammonium chloride, 10% hexadecylbenzyl dimethyl ammonium chloride (ceta chloride), the chinese generic name benzalkonium chloride: the organic and quick sterilization is carried out,
chlorinated C8-C10 double-chain alkyl dimethyl quaternary ammonium salt: the organic and quick sterilization is carried out,
brominated C8-C10 double-chain alkyl dimethyl quaternary ammonium salt: the organic and quick sterilization is carried out,
the content of the quaternary ammonium salts can be adjusted, but the total content is accurately controlled to be about 0.1 percent of 5 percent concentration error.
1% of few-layer graphene (3-10 layers): the ion quantity is slowly released and stabilized, the continuous bacteriostasis time is longer,
90% of water: solvent, deionized water is used as water in the production process,
the preparation method of the product of the invention can not use pure water to be poured into a container filled with the formula, but can pour the formula into the pure water in turn.
The product of the invention takes water as a solvent, adopts a physical principle to comprehensively sterilize inorganic nano and micron zinc oxide/silver oxide fine particles and organic quaternary ammonium salt, has rapidity close to one-time chemical disinfection and sterilization and persistence similar to silver ion sterilization and bacteriostasis, obtains zinc chloride through the reaction, and the zinc chloride is dissolved in water, cannot lose efficacy due to contact with chloride, has the characteristics of no color, no odor and no bleaching, has lower cost than silver ion sterilization, and greatly saves the cost.
The working principle of the invention is as follows: the product of the invention is called MY19 disinfection stock solution after being prepared, and is concentrated solution. When in use, the MY1k disinfectant is used after being mixed with water according to the ratio of 1:19 of the disinfection stock solution to the water, namely diluted by 20 times.
Laboratory tests prove that the quaternary ammonium salt component in the diluted MY1k disinfectant has a 5-minute killing rate of 99.99% for common escherichia coli, candida albicans and staphylococcus aureus. Moreover, the MY1k disinfectant is colorless and odorless (extremely light smell), has no bleaching property, and has no influence on the surface of colored object fabric. Meanwhile, the fabric has the functions of softening, finishing and removing wrinkles for clothes made of acetate fibers.
After other organic and chemical disinfectants are disinfected, the surfaces of the disinfectants are dried, and then the disinfectants do not have the bactericidal and bacteriostatic effects, if the disinfectants touch, the disinfectants need to be disinfected again, after the products are quickly disinfected and disinfected, the micron-sized zinc oxide particles can continuously generate photocatalysis under the combined action of trace moisture (moisture in the air can meet the requirements) and visible light, active oxygen ions are generated, and the disinfectants continuously perform bacteriostasis and sterilization, and the catalysis does not consume the micron-sized zinc oxide particles, so the disinfectants have long-acting bacteriostasis and sterilization effects.
The diameter of the bacteria is generally 0.5-5 microns, namely 500-5000 nm, and the diameter of the virus is 18-100 nm. The virus cannot survive alone and must be parasitic in human or animal cells or bacteria. The covalent radius of the zinc ions is about 122 picometers, namely the diameter is about 0.244 nanometers, namely, bacteria are dozens to hundreds of times as large as viruses, and viruses are dozens to hundreds of times as large as the zinc ions. The nanometer zinc oxide contained in the product has the main functions of dissolving out zinc ions, wherein the zinc ions are positive ions with positive points, bioelectricity on the surfaces of bacteria and viruses is negative, the zinc ions can directly enter the inside of the bacteria to interfere the normal enzyme activity in the bacteria to cause the bacteria to die, and meanwhile, the zinc ions have high extracellular concentration to form ion concentration difference to destroy and interfere the polarization state of cell membranes to cause the bacteria to die because the bacteria cannot normally absorb and discharge metabolites. After the bacteria die, the zinc ions can be continuously adsorbed in a free mode or enter other bacteria for continuous sterilization, and viruses cannot be replicated and transmitted without the bacteria as a carrier.
The nano-micron zinc oxide still has 99.9 percent of sterilization rate after 4 years by a simulated accelerated aging test carried out by the method of ASTM F1980.
The few layers of graphene (3-10 layers) are mainly added to serve as intermediate layers to enable zinc ions and nano zinc oxide particles to be better attached to the surface of an object and not to fall off easily, so that the adhesiveness of zinc oxide on the surface is enhanced, and the bacteriostatic time is prolonged.
The quaternary ammonium salt in the formula is a disinfectant component for food, which can be used in list (2009 edition) of disinfectant raw materials (components) for food. (disinfectant for foods means a substance directly used for disinfecting foods, tableware and tools, equipments or food packaging materials and containers which directly contact foods.)
Zinc oxide is a safe and nontoxic substance, and can be added into most face sunscreen, whitening and baby toilet powder.
The present invention and its embodiments have been described above, but the description is not limitative, and the actual structure is not limited thereto. It should be understood that those skilled in the art should understand that they can easily make various changes, substitutions and alterations herein without departing from the spirit and scope of the invention as defined by the appended claims.
Claims (3)
1. The formula of the nano physical composite bactericidal and bacteriostatic agent is characterized in that: the composite material comprises raw materials of nano-scale zinc oxide powder, micron-scale zinc oxide powder, a dodecyl-hexadecyl benzyl dimethyl ammonium chloride quaternary ammonium salt mixture, C8-C10 double-chain alkyl dimethyl quaternary ammonium salt chloride, C8-C10 double-chain alkyl dimethyl quaternary ammonium salt bromide, few-layer graphene and pure water.
2. The formulation of the nano-physical composite bactericidal and bacteriostatic agent according to claim 1, wherein: the raw materials comprise, by weight, 1-4% of nano-scale zinc oxide powder, 1-2% of micron-scale zinc oxide powder, less than 4% of dodecyl to hexadecyl benzyl dimethyl ammonium chloride quaternary ammonium salt mixture, less than 2% of chlorinated C8-C10 double-chain alkyl dimethyl quaternary ammonium salt, less than 1% of brominated C8-C10 double-chain alkyl dimethyl quaternary ammonium salt, 1-3% of few-layer graphene and 90-95% of pure water.
3. A method for preparing a nano physical composite sterilizing and bacteriostat is characterized in that: it comprises the following steps:
1) the formula of any one of claims 1-2 is added to pure water sequentially at normal temperature, and stirred at low speed for 120 seconds.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202010945359.1A CN112106785A (en) | 2020-09-10 | 2020-09-10 | Formula of nano physical composite bactericidal and bacteriostatic agent and preparation method thereof |
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| CN202010945359.1A CN112106785A (en) | 2020-09-10 | 2020-09-10 | Formula of nano physical composite bactericidal and bacteriostatic agent and preparation method thereof |
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| CN112106785A true CN112106785A (en) | 2020-12-22 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113600003A (en) * | 2021-06-30 | 2021-11-05 | 南京凯创协同纳米技术有限公司 | Spray for quickly eliminating cigarette smell and preparation method thereof |
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| CN107926941A (en) * | 2017-11-15 | 2018-04-20 | 惠州市环美盛新材料有限公司 | A kind of zinc oxide antibacterial mildew inhibitor and its preparation method and application |
| CN108912686A (en) * | 2018-07-16 | 2018-11-30 | 江苏万纳普新材料科技有限公司 | A kind of high-efficiency antimicrobial toughening flame-proof Multi-functional plastic masterbatch and preparation method thereof |
| CN111109259A (en) * | 2019-12-27 | 2020-05-08 | 江苏神涛环保科技有限公司 | Composite sterilizing disinfectant |
-
2020
- 2020-09-10 CN CN202010945359.1A patent/CN112106785A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107926941A (en) * | 2017-11-15 | 2018-04-20 | 惠州市环美盛新材料有限公司 | A kind of zinc oxide antibacterial mildew inhibitor and its preparation method and application |
| CN108912686A (en) * | 2018-07-16 | 2018-11-30 | 江苏万纳普新材料科技有限公司 | A kind of high-efficiency antimicrobial toughening flame-proof Multi-functional plastic masterbatch and preparation method thereof |
| CN111109259A (en) * | 2019-12-27 | 2020-05-08 | 江苏神涛环保科技有限公司 | Composite sterilizing disinfectant |
Non-Patent Citations (2)
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| 何铁林 等，: "《水处理化学品手册》", 31 May 2000, 化学工业出版社 * |
| 朱洪法 等，: "《工业助剂手册》", 30 June 2007, 金盾出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113600003A (en) * | 2021-06-30 | 2021-11-05 | 南京凯创协同纳米技术有限公司 | Spray for quickly eliminating cigarette smell and preparation method thereof |
| CN113600003B (en) * | 2021-06-30 | 2023-09-12 | 南京凯创协同纳米技术有限公司 | Spray for rapidly eliminating cigarette smell and preparation method thereof |
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