CN112089885A - Absorbable collagen suture line and forming preparation method thereof - Google Patents
Absorbable collagen suture line and forming preparation method thereof Download PDFInfo
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- CN112089885A CN112089885A CN202011234072.4A CN202011234072A CN112089885A CN 112089885 A CN112089885 A CN 112089885A CN 202011234072 A CN202011234072 A CN 202011234072A CN 112089885 A CN112089885 A CN 112089885A
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- enteric
- chinese medicine
- traditional chinese
- thread
- suture
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
- A61L17/06—At least partially resorbable materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
- A61L17/005—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters containing a biologically active substance, e.g. a medicament or a biocide
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
- A61L17/06—At least partially resorbable materials
- A61L17/08—At least partially resorbable materials of animal origin, e.g. catgut, collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
- A61L17/14—Post-treatment to improve physical properties
- A61L17/145—Coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/30—Compounds of undetermined constitution extracted from natural sources, e.g. Aloe Vera
Abstract
The invention relates to the technical field of suture preparation, in particular to an absorbable collagen suture and a forming preparation method thereof, which comprises the following components: the enteric soluble line, the collagen, the traditional Chinese medicine solution and the gel comprise the following steps: preparing and cleaning a goat sausage casing, and cutting the goat sausage casing into an enteric-coated line; soaking the enteric thread in a traditional Chinese medicine solution; immersing the enteric-coated thread soaked by the traditional Chinese medicine into collagen and gel liquid for soaking; drying and forming the obtained enteric-coated rope; in addition, the suture thread is deeply soaked, so that the traditional Chinese medicine components inside the suture thread can be quickly permeated into the internal tissues of the enteric thread, the traditional Chinese medicine inside the suture thread can be gradually permeated and transferred to the wound along with the decomposition of the enteric thread after the wound is sutured, the effect of promoting the healing of the wound is achieved, and the healing effect of the suture thread on the wound is improved.
Description
Technical Field
The invention relates to the technical field of suture preparation, in particular to an absorbable collagen suture and a forming preparation method thereof.
Background
Absorbable suture thread, which can be absorbed by human body after wound healing. The common absorbable suture line material is prepared by utilizing catgut, animal tendon, human hair and the like; as such, the biological suture is widely used in clinical application, and can be widely applied to operations of gynecology, obstetrics, surgery, plastic surgery, urology surgery, pediatrics, stomatology, otorhinolaryngology, ophthalmology and the like and suture of intracutaneous soft tissues.
Research and clinical tests prove that when the collagen suture line is used for suturing the surgical incision, the collagen suture line is gradually absorbed along with the healing of the wound, the wound healing is good, and the collagen suture line is very suitable for being used as the suture line.
Although current absorbable sutures can achieve the problem of being free of stitches, they generally provide only a suture effect after closing a wound, and do not provide other effects.
Disclosure of Invention
In order to solve one of the technical problems, the invention adopts the technical scheme that: an absorbable collagen suture comprising the following components: enteric soluble line, collagen, Chinese medicinal solution, and gel.
Preferably, the traditional Chinese medicine solution comprises the following powdered components: notoginseng radix, sanguis Draxonis, caulis Sargentodoxae, lignum sappan, and herba Saxifragae.
Preferably, the traditional Chinese medicine components of the traditional Chinese medicine solution penetrate into the enteric thread.
Preferably, the traditional Chinese medicine solution comprises the following components in parts by weight: 10-20 parts of pseudo-ginseng, 10-15 parts of dragon's blood, 20-30 parts of sargentgloryvine stem, 5-10 parts of sappan wood and 10-15 parts of anemone rivularis.
Preferably, the enteric thread is made by a weaving process.
Preferably, the enteric soluble thread is goat enteric soluble thread.
The forming preparation method of the absorbable collagen suture line comprises the following steps:
7.1, preparing and washing a goat sausage casing, and cutting the goat sausage casing into an enteric-coated line, wherein the width of the cut enteric-coated line is 2 mm;
7.2, weaving the 3 obtained enteric threads into strands, and knotting two ends of the strands to obtain enteric thread;
7.3, sterilizing and disinfecting the enteric thread;
7.4, soaking the enteric thread in a traditional Chinese medicine solution;
7.5, immersing the enteric-coated strings after the traditional Chinese medicine soaking into the collagen and the gel liquid for soaking;
7.6, placing the obtained enteric-coated thread in a forming device of an absorbable collagen suture line for drying and forming treatment;
7.7, obtaining the final suture.
Preferably, ultrasonic oscillation is required during the soaking treatment of the traditional Chinese medicine solution, so as to promote the traditional Chinese medicine components in the traditional Chinese medicine solution to be fully soaked into the enteric thread.
Preferably, the soaking treatment time of the traditional Chinese medicine solution is 3-5 hours; immersing in collagen and gel solution for 6-10 hr.
Preferably, the molding equipment for absorbable collagen suture lines comprises two oppositely arranged pressing modules, the two pressing modules are used for matching to realize the press molding of the suture lines, two thrust assemblies are respectively installed on two sides of each pressing module, and each thrust assembly respectively controls the movement of the pressing module at the corresponding position.
Preferably, press the module and include a press die press the inside wall of press die to be provided with a plurality of cross-section for sectorial pressure grooving along its length direction interval respectively on the inside wall, press die's inside to be the cavity setting press die internally mounted has the cold and hot double-purpose fan of a plurality of, each be provided with a plurality of bleeder vent on the inside wall of pressure grooving, each the lateral wall of pressure grooving is the heat conduction sheetmetal, the heat conduction sheetmetal passes through the wire and links to each other with outside heating power supply.
The invention has the beneficial effects that: the suture line is woven by utilizing the enteric-coated thread, so that the strength of the suture line can be effectively improved when the suture line is used, in addition, the traditional Chinese medicine components in the suture line can quickly permeate into the internal tissues of the enteric-coated thread by deeply soaking the suture line, so that the traditional Chinese medicine in the suture line can gradually permeate and transfer to a wound along with the decomposition of the enteric-coated thread after the wound is sutured, the effect of promoting the healing of the wound is achieved, and the healing effect of the suture line on the wound is improved; meanwhile, the collagen and the gel can effectively promote the healing of the wound.
Drawings
In order to more clearly illustrate the detailed description of the invention or the technical solutions in the prior art, the drawings that are needed in the detailed description of the invention or the prior art will be briefly described below. Throughout the drawings, like elements or components are generally identified by like reference numerals. In the drawings, elements or components are not necessarily drawn to scale.
Fig. 1 is a schematic structural view of the forming apparatus of the absorbable collagen suture line of the present invention.
Fig. 2 is a schematic structural diagram of a pressing module of the forming apparatus for absorbable collagen suture of the present invention.
In the figure, 1, a pressing module; 2. pressing the die; 3. rope pressing grooves; 4. a cold and hot dual-purpose fan; 5. air holes are formed; 6. a heat conductive metal sheet; 7. a heating power supply; 8. a thrust assembly; 9. and (4) a thrust electric cylinder.
Detailed Description
Embodiments of the present invention will be described in detail below with reference to the accompanying drawings. The following examples are only for illustrating the technical solutions of the present invention more clearly, and therefore are only examples, and the protection scope of the present invention is not limited thereby.
As shown in fig. 1-2, an absorbable collagen suture comprising the following components: enteric soluble line, collagen, Chinese medicinal solution, and gel.
The collagen, the traditional Chinese medicine solution and the gel are matched and attached to the inner part and the surface of the enteric thread, so that the effect of the suture thread on promoting wound healing can be effectively improved.
Preferably, the traditional Chinese medicine solution comprises the following powdered components: notoginseng radix, sanguis Draxonis, caulis Sargentodoxae, lignum sappan, and herba Saxifragae.
Preferably, the traditional Chinese medicine components of the traditional Chinese medicine solution penetrate into the enteric thread.
Preferably, the traditional Chinese medicine solution comprises the following components in parts by weight: 10-20 parts of pseudo-ginseng, 10-15 parts of dragon's blood, 20-30 parts of sargentgloryvine stem, 5-10 parts of sappan wood and 10-15 parts of anemone rivularis.
The interaction of various traditional Chinese medicine components can effectively improve the treatment on the wound, and the suture line is ensured, and meanwhile, the treatment effect on the wound is realized.
Preferably, the enteric thread is made by a weaving process.
Preferably, the intestinal lysis line is a goat intestinal lysis line, and the adoption of the goat intestinal lysis line can better ensure the tensile strength of the goat intestinal lysis line.
The forming preparation method of the absorbable collagen suture line comprises the following steps:
7.1, preparing and washing a goat sausage casing, and cutting the goat sausage casing into an enteric-coated line, wherein the width of the cut enteric-coated line is 2 mm;
7.2, weaving the 3 obtained enteric threads into strands, and knotting two ends of the strands to obtain enteric thread;
the structural strength of the whole suture line can be effectively improved by arranging a plurality of enteric threads to be mutually woven into strands.
7.3, sterilizing and disinfecting the enteric thread to ensure the treatment of internal bacteria;
7.4, soaking the enteric thread in a traditional Chinese medicine solution;
the strands of the plurality of enteric threads are woven with each other, so that the efficiency of the traditional Chinese medicine components entering the inside of a single enteric thread can be effectively improved when the traditional Chinese medicine solution is soaked in the later stage, and meanwhile, the traditional Chinese medicine components can be effectively remained in the gaps between the enteric threads which are tightly woven, so that the amount of the traditional Chinese medicine components in the whole enteric thread is increased, and the sufficient traditional Chinese medicine components can be conveniently infiltrated into the wound after the later stage is sewed.
7.5, immersing the enteric-coated strings after the traditional Chinese medicine soaking into the collagen and the gel liquid for soaking;
the collagen and the gel solution are soaked, so that the intestinal solution can further absorb the gel solution and the collagen and temporarily store the collagen on the surface of the intestinal solution, and the purpose of treating the wound can be achieved when the intestinal solution is sutured on the wound.
7.6, placing the obtained enteric-coated thread in a forming device of an absorbable collagen suture line for drying and forming treatment;
drying and molding to obtain suture containing Chinese medicinal components, collagen and gel.
7.7, obtaining the final suture.
Preferably, ultrasonic oscillation is required during the soaking treatment of the traditional Chinese medicine solution, so as to promote the traditional Chinese medicine components in the traditional Chinese medicine solution to be fully soaked into the enteric thread.
The ultrasonic oscillation is mainly used for improving the effect of the traditional Chinese medicine solution entering the interior of the enteric thread and ensuring that the interior of the enteric thread is filled with sufficient traditional Chinese medicine components.
Preferably, the soaking treatment time of the traditional Chinese medicine solution is 3-5 hours; immersing in collagen and gel solution for 6-10 hr.
Preferably, the molding equipment for absorbable collagen suture comprises two oppositely arranged pressing modules 1, the two pressing modules 1 are used for matching to realize the press molding of the suture, two thrust assemblies 8 are respectively installed on two sides of the pressing modules 1, and each thrust assembly 8 respectively controls the movement of the pressing module 1 at the corresponding position of the pressing module 1.
The thrust assembly 8 is two thrust electric cylinders 9 vertically arranged at intervals, the cylinder body of each thrust electric cylinder 9 is respectively and fixedly arranged relative to the ground, and the two thrust electric cylinders 9 on the same thrust assembly 8 move synchronously.
When carrying out the final dry forming of stylolite and handling, because the surface of stylolite contains collagen and gel liquid, can control corresponding pressing module 1 through starting two thrust assemblies 8 and realize pressing each other to the realization realizes hot pressing to the stylolite of placing above that, can make the collagen and the gel on stylolite surface step by step dry and attach to its surface at the in-process of pressing.
Preferably, press module 1 to include one and press die 2's inside wall to be provided with a plurality of cross-section for sectorial pressure rope groove 3 along its length direction interval respectively on press die 2's the inside to be the cavity setting press die 2 internally mounted has cold and hot double-purpose fan 4 of a plurality of, each be provided with a plurality of bleeder vent 5 on press rope groove 3's the inside wall, each press rope groove 3's lateral wall to be heat conduction sheetmetal 6, heat conduction sheetmetal 6 passes through the wire and links to each other with outside heating power supply 7.
To wait to press down fashioned stylolite and place in each rope groove 3 that corresponds on the press die 2 of below in proper order, then control two thrust assemblies 8 relative motion, this moment can compress tightly each stylolite, the cold and hot double-purpose fan 4 of simultaneous control is opened hot-blastly, thereby realize hot-blast heating, and control outside heating power 7 carries out the heating of suitable temperature to each heat conduction sheetmetal 6, finally realize the degree that each component and stylolite infiltration will be further promoted, close heat conduction sheetmetal 6 after hot-blast a period of time at once, adjust the air-out of cold and hot double-purpose fan 4 into low temperature cold wind simultaneously, finally realize compressing tightly the shaping to the stylolite.
The suture line is woven by utilizing the enteric-coated thread, so that the strength of the suture line can be effectively improved when the suture line is used, in addition, the traditional Chinese medicine components in the suture line can quickly permeate into the internal tissues of the enteric-coated thread by deeply soaking the suture line, so that the traditional Chinese medicine in the suture line can gradually permeate and transfer to a wound along with the decomposition of the enteric-coated thread after the wound is sutured, the effect of promoting the healing of the wound is achieved, and the healing effect of the suture line on the wound is improved; meanwhile, the collagen and the gel can effectively promote the healing of the wound
The above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; the modifications or the substitutions do not cause the essence of the corresponding technical solutions to depart from the scope of the technical solutions of the embodiments of the present invention, and the technical solutions are all covered in the scope of the claims and the specification of the present invention; it will be apparent to those skilled in the art that any alternative modifications or variations to the embodiments of the present invention may be made within the scope of the present invention.
The present invention is not described in detail, but is known to those skilled in the art.
Claims (9)
1. Absorbable collagen suture line which is characterized in that: comprises the following components: enteric soluble line, collagen, Chinese medicinal solution, and gel.
2. The absorbable collagen suture of claim 1, wherein: the traditional Chinese medicine solution comprises the following powdered components: notoginseng radix, sanguis Draxonis, caulis Sargentodoxae, lignum sappan, and herba Saxifragae.
3. The absorbable collagen suture of claim 1, wherein: the traditional Chinese medicine components of the traditional Chinese medicine solution penetrate into the enteric thread.
4. The absorbable collagen suture of claim 1, wherein: the traditional Chinese medicine solution comprises the following components in parts by weight: 10-20 parts of pseudo-ginseng, 10-15 parts of dragon's blood, 20-30 parts of sargentgloryvine stem, 5-10 parts of sappan wood and 10-15 parts of anemone rivularis.
5. The absorbable collagen suture of claim 1, wherein: the enteric-coated thread is made by a weaving process.
6. The absorbable collagen suture of claim 1, wherein: the intestinal lysis line is goat intestinal lysis line.
7. The forming preparation method of the absorbable collagen suture line is characterized by comprising the following steps: the method comprises the following steps:
7.1, preparing and washing a goat sausage casing, and cutting the goat sausage casing into an enteric-coated line, wherein the width of the cut enteric-coated line is 2 mm;
7.2, weaving the 3 obtained enteric threads into strands, and knotting two ends of the strands to obtain enteric thread;
7.3, sterilizing and disinfecting the enteric thread;
7.4, soaking the enteric thread in a traditional Chinese medicine solution;
7.5, immersing the enteric-coated strings after the traditional Chinese medicine soaking into the collagen and the gel liquid for soaking;
7.6, placing the obtained enteric-coated thread in a forming device of an absorbable collagen suture line for drying and forming treatment;
7.7, obtaining the final suture.
8. The method for preparing the absorbable collagen suture line according to claim 7, wherein: ultrasonic oscillation is needed in the process of soaking treatment of the traditional Chinese medicine solution, so that the traditional Chinese medicine components in the traditional Chinese medicine solution are promoted to be fully soaked into the enteric-coated strings.
9. The method for preparing the absorbable collagen suture line according to claim 7, wherein: soaking the Chinese medicinal solution for 3-5 hr; immersing in collagen and gel solution for 6-10 hr.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011234072.4A CN112089885A (en) | 2020-11-07 | 2020-11-07 | Absorbable collagen suture line and forming preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011234072.4A CN112089885A (en) | 2020-11-07 | 2020-11-07 | Absorbable collagen suture line and forming preparation method thereof |
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| CN112089885A true CN112089885A (en) | 2020-12-18 |
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| CN202011234072.4A Pending CN112089885A (en) | 2020-11-07 | 2020-11-07 | Absorbable collagen suture line and forming preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113663115A (en) * | 2021-08-23 | 2021-11-19 | 山东博达医疗用品股份有限公司 | Preparation method of collagen-coated absorbable medical suture |
| CN115089757A (en) * | 2022-07-28 | 2022-09-23 | 单县华宇缝合制品有限公司 | Processing method of self-degradation type suture line |
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2020
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| AU2016202877A1 (en) * | 2012-05-16 | 2016-05-26 | Sewon Cellontech Co. Ltd | Composition for repairing cartilage tissue, method for producing same, and use thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113663115A (en) * | 2021-08-23 | 2021-11-19 | 山东博达医疗用品股份有限公司 | Preparation method of collagen-coated absorbable medical suture |
| CN115089757A (en) * | 2022-07-28 | 2022-09-23 | 单县华宇缝合制品有限公司 | Processing method of self-degradation type suture line |
| CN115089757B (en) * | 2022-07-28 | 2024-04-12 | 单县华宇缝合制品有限公司 | Processing technology method of self-degradable suture line |
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Application publication date: 20201218 |