CN112089795A - A Chinese medicinal composition for relieving asthenopia and treating myopia, and its preparation method - Google Patents

A Chinese medicinal composition for relieving asthenopia and treating myopia, and its preparation method Download PDF

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CN112089795A
CN112089795A CN202011149383.0A CN202011149383A CN112089795A CN 112089795 A CN112089795 A CN 112089795A CN 202011149383 A CN202011149383 A CN 202011149383A CN 112089795 A CN112089795 A CN 112089795A
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杨浩
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482Cassia, e.g. golden shower tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536Prunella or Brunella (selfheal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8984Dendrobium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/10Ophthalmic agents for accommodation disorders, e.g. myopia

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Abstract

The invention provides a traditional Chinese medicine composition for relieving asthenopia and treating myopia and a preparation method thereof, belonging to the technical field of medicines. The invention provides a traditional Chinese medicine composition for relieving asthenopia and treating myopia, which mainly comprises the following components in parts by weight: 13-27 parts of angelica sinensis, 7-13 parts of semen cassiae, 9-15 parts of salvia miltiorrhiza, 5-15 parts of mulberry leaves, 7-13 parts of selfheal, 6-14 parts of dendrobium nobile and 8-12 parts of pearl powder. The cassia seed powder is used as the monarch drug, is combined with the traditional Chinese medicine formula named as Guangming powder, and has the effects of improving eyesight, removing nebula, dispelling wind, clearing heat, eliminating dampness and relieving itching.

Description

A Chinese medicinal composition for relieving asthenopia and treating myopia, and its preparation method
Technical Field
The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for relieving asthenopia and treating myopia and a preparation method thereof.
Background
Asthenopia, a common ophthalmic disease named after symptoms, is classified in the category of "liver fatigue" or "glabellar bone pain" by traditional Chinese medicine, and is considered to be caused by long-term mental strain, loss of spleen qi, or loss of essence and blood of liver and kidney, and incapability of nourishing eyes and orifices.
Asthenopia not only causes swelling, ophthalmalgia, dry eye, burning sensation, lacrimation, itching, foreign body sensation and orbital pain, but also can cause symptoms such as fatigue, headache, dizziness, memory loss, serious nausea, vomiting and the like, and neurological symptoms such as anxiety, irritability and the like. Long-term asthenopia also increases the incidence of myopia.
The existing mode for relieving the asthenopia is mostly solved by dropping eye drops, and the problems of unsatisfactory effect and incapability of radical treatment exist.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition for relieving asthenopia and treating myopia and a preparation method thereof. The invention belongs to the field of traditional Chinese medicine treatment, mainly based on the principle of tonifying deficiency and activating blood, and uses the medicines for activating blood circulation, removing blood stasis, relaxing channels and activating collaterals, thereby achieving the purposes of directly permeating the medicines into channels and collaterals and acupuncture points around eyes, promoting the normal circulation of qi and blood and fundamentally solving the asthenopia. The eye cream can relieve visual fatigue in real time, and has obvious effects on dry eyes, itching, foreign body sensation, orbital pain and other symptoms through the transdermal attraction characteristic of the medicine.
In order to achieve the above object, the present invention provides the following technical solutions:
the invention provides a traditional Chinese medicine composition for relieving asthenopia and treating myopia, which mainly comprises the following components in parts by weight:
13-27 parts of angelica sinensis, 7-13 parts of semen cassiae, 9-15 parts of salvia miltiorrhiza, 5-15 parts of mulberry leaves, 7-13 parts of selfheal, 6-14 parts of dendrobium nobile and 8-12 parts of pearl powder.
Preferably, the traditional Chinese medicine composition mainly comprises the following raw materials in parts by weight:
15-25 parts of angelica sinensis, 9-11 parts of semen cassiae, 10-13 parts of salvia miltiorrhiza, 8-12 parts of mulberry leaves, 9-11 parts of selfheal, 8-12 parts of dendrobium nobile and 9-11 parts of pearl powder.
Preferably, the traditional Chinese medicine composition mainly comprises the following raw materials in parts by weight:
20 parts of angelica, 10 parts of cassia seed, 10 parts of salvia miltiorrhiza, 10 parts of mulberry leaf, 10 parts of selfheal, 10 parts of dendrobium and 10 parts of pearl powder.
The invention provides a preparation method of a traditional Chinese medicine composition for relieving asthenopia and treating myopia, which comprises the following steps:
drying and pulverizing radix Angelicae sinensis, semen Cassiae, Saviae Miltiorrhizae radix, folium Mori, Prunellae Spica, and herba Dendrobii respectively, and mixing the pulverized powders to obtain mixture;
mixing the pearl powder and the mixture to obtain the traditional Chinese medicine composition.
Preferably, the drying treatment temperature is 40-80 ℃, and the time is 12-36 h.
Preferably, the crushing treatment is to 80-120 meshes.
The invention has the beneficial effects that:
compared with the traditional eye drop, the invention has the unique characteristics that:
1. the medicine can quickly reach the part causing asthenopia, accelerate the free diffusion of medicine property at the acupuncture points and the channels and collaterals around the eyes, and quickly dredge qi and blood, so that the whole body is enabled to be 'meridian-vessel dredging and qi and blood circulation promoting'.
2. Aiming at the asthenopia caused by factors such as deficiency of qi and blood, decline of yang qi and the like, the invention can activate the cell metabolism of each organ of the eyes, repair and breed the damaged cells, quickly relieve the asthenopia phenomenon, improve and promote the eyesight of the naked eyes, and has the obvious advantages of promoting blood circulation to remove blood stasis and promoting the circulation of qi and blood.
3. The traditional Chinese medicine composition provided by the invention evolves according to the proved prescription of Guangming powder of Ming Dynasty medical work 'shou Shi Baoyuan', and comprises seven traditional Chinese medicines such as angelica sinensis, semen cassiae, salvia miltiorrhiza, mulberry leaves, selfheal, dendrobium, pearl powder and the like. The formula of the traditional Chinese medicine powder takes semen cassiae as a monarch, combines a traditional proved formula of traditional Chinese medicine, namely the guangming powder, and has the effects of improving eyesight, removing nebula, dispelling wind, clearing heat, eliminating dampness and relieving itching.
Detailed Description
The invention provides a traditional Chinese medicine composition for relieving asthenopia and treating myopia, which mainly comprises the following components in parts by weight:
13-27 parts of angelica sinensis, 7-13 parts of semen cassiae, 9-15 parts of salvia miltiorrhiza, 5-15 parts of mulberry leaves, 7-13 parts of selfheal, 6-14 parts of dendrobium nobile and 8-12 parts of pearl powder.
In the invention, the traditional Chinese medicine composition for relieving asthenopia and treating myopia comprises 13-27 parts, preferably 15-25 parts, more preferably 20 parts of angelica by weight, and the angelica has the following functions: mainly used for enriching blood, promoting blood circulation, regulating menstruation, relieving pain, moistening dryness and lubricating intestines; it is mainly used for treating flaccid paralysis, numbness of skin, carbuncle, ulcer, traumatic injury.
In the invention, the traditional Chinese medicine composition for relieving asthenopia and treating myopia comprises 7-13 parts by weight of cassia seeds, preferably 9-11 parts by weight of cassia seeds, more preferably 10 parts by weight of cassia seeds, and has the following functions: clearing liver, improving vision, moistening intestine and relaxing bowels; it can be used for treating conjunctival congestion, photophobia, lacrimation, headache, vertigo, and dim eyesight.
In the invention, the traditional Chinese medicine composition for relieving asthenopia and treating myopia comprises 9-15 parts, preferably 10-13 parts, more preferably 10 parts of salvia miltiorrhiza, and the salvia miltiorrhiza has the following functions: promoting blood circulation, removing blood stasis, dredging channels, relieving pain, clearing heart fire, relieving restlessness, cooling blood, and eliminating carbuncle; it is mainly used for treating pain due to heat arthralgia, sore and ulcer with swelling and pain.
In the invention, the traditional Chinese medicine composition for relieving asthenopia and treating myopia comprises 5-15 parts by weight of mulberry leaves, preferably 8-12 parts by weight of mulberry leaves, more preferably 10 parts by weight of mulberry leaves, and has the following functions: disperse wind-heat, clear lung-heat and moisten dryness, calm liver and improve vision, cool blood and stop bleeding; it is mainly used for treating dizziness due to hyperactivity of liver-yang, conjunctival congestion and blurred vision.
In the invention, the traditional Chinese medicine composition for relieving asthenopia and treating myopia comprises, by weight, 7-13 parts of selfheal, preferably 9-11 parts of selfheal, more preferably 10 parts of selfheal, and the selfheal has the following effects: clear heat and purge fire, improve vision, dissipate nodulation and relieve swelling.
In the invention, the traditional Chinese medicine composition for relieving asthenopia and treating myopia comprises, by weight, 6-14 parts of dendrobium, preferably 8-12 parts of dendrobium, more preferably 10 parts of dendrobium: the functional indications are as follows: to nourish yin, clear heat, improve eyesight and strengthen waist.
In the invention, the traditional Chinese medicine composition for relieving asthenopia and treating myopia comprises 8-12 parts by weight of pearl powder, preferably 9-11 parts by weight of pearl powder, more preferably 10 parts by weight of pearl powder, and has the following effects: tranquilization and arresting convulsion, clearing heat and nourishing yin, improving eyesight and detoxifying; for eye diseases such as blood-shot eyes with swelling and pain, nebula covering the eyes, etc., it can clear liver, remove nebula and improve vision.
The invention also provides a preparation method of the traditional Chinese medicine composition for relieving asthenopia and treating myopia, which comprises the following steps:
drying and pulverizing radix Angelicae sinensis, semen Cassiae, Saviae Miltiorrhizae radix, folium Mori, Prunellae Spica, and herba Dendrobii respectively, and mixing the pulverized powders to obtain mixture;
mixing the pearl powder and the mixture to obtain the traditional Chinese medicine composition.
In the invention, the drying temperature is 40-80 ℃, preferably 60 ℃; the drying time is 12-36 h, preferably 24 h.
In the invention, the crushing treatment is to crush to 80-120 meshes, preferably 100 meshes.
The technical solutions provided by the present invention are described in detail below with reference to examples, but they should not be construed as limiting the scope of the present invention.
Example 1
Embodiment 1 provides a traditional Chinese medicine composition for relieving asthenopia and treating myopia, which mainly comprises the following components in parts by weight:
13 parts of angelica, 7 parts of cassia seed, 9 parts of salvia miltiorrhiza, 5 parts of mulberry leaf, 7 parts of selfheal, 6 parts of dendrobium and 8 parts of pearl powder.
Drying radix Angelicae sinensis, semen Cassiae, Saviae Miltiorrhizae radix, folium Mori, Prunellae Spica, and herba Dendrobii at 60 deg.C for 24 hr; pulverizing the dried components in a wall-breaking pulverizer, pulverizing to 100 mesh to obtain mixture, and mixing the Margarita powder and the mixture to obtain the Chinese medicinal composition.
Example 2
Embodiment 2 provides a traditional Chinese medicine composition for relieving asthenopia and treating myopia, which mainly comprises the following components in parts by weight:
14 parts of angelica, 10 parts of cassia seed, 10 parts of salvia miltiorrhiza, 8 parts of mulberry leaf, 8 parts of selfheal, 8 parts of dendrobium and 10 parts of pearl powder.
Drying radix Angelicae sinensis, semen Cassiae, Saviae Miltiorrhizae radix, folium Mori, Prunellae Spica, and herba Dendrobii at 80 deg.C for 12 hr; pulverizing the dried components in a wall-breaking pulverizer, pulverizing to 100 mesh to obtain mixture, and mixing the Margarita powder and the mixture to obtain the Chinese medicinal composition.
Example 3
Embodiment 3 provides a traditional Chinese medicine composition for relieving asthenopia and treating myopia, which mainly comprises the following components in parts by weight:
18 parts of angelica, 10 parts of cassia seed, 12 parts of salvia miltiorrhiza, 12 parts of mulberry leaf, 10 parts of selfheal, 10 parts of dendrobium and 9 parts of pearl powder.
Drying radix Angelicae sinensis, semen Cassiae, Saviae Miltiorrhizae radix, folium Mori, Prunellae Spica, and herba Dendrobii at 50 deg.C for 30 hr; pulverizing the dried components in a wall-breaking pulverizer, pulverizing to 120 mesh to obtain mixture, and mixing the Margarita powder and the mixture to obtain the Chinese medicinal composition.
Example 4
Embodiment 4 provides a traditional Chinese medicine composition for relieving asthenopia and treating myopia, which mainly comprises the following components in parts by weight:
20 parts of angelica, 10 parts of cassia seed, 10 parts of salvia miltiorrhiza, 10 parts of mulberry leaf, 10 parts of selfheal, 10 parts of dendrobium and 10 parts of pearl powder.
Drying radix Angelicae sinensis, semen Cassiae, Saviae Miltiorrhizae radix, folium Mori, Prunellae Spica, and herba Dendrobii at 60 deg.C for 24 hr; pulverizing the dried components in a wall-breaking pulverizer, pulverizing to 100 mesh to obtain mixture, and mixing the Margarita powder and the mixture to obtain the Chinese medicinal composition.
Example 5
Embodiment 5 provides a traditional Chinese medicine composition for relieving asthenopia and treating myopia, which mainly comprises the following components in parts by weight:
25 parts of angelica, 11 parts of cassia seed, 10 parts of salvia miltiorrhiza, 6 parts of mulberry leaf, 12 parts of selfheal, 9 parts of dendrobium and 11 parts of pearl powder.
Drying radix Angelicae sinensis, semen Cassiae, Saviae Miltiorrhizae radix, folium Mori, Prunellae Spica, and herba Dendrobii at 70 deg.C for 24 hr; pulverizing the dried components in a wall-breaking pulverizer, pulverizing to 80 mesh to obtain mixture, and mixing the Margarita powder and the mixture to obtain the Chinese medicinal composition.
Examples of the experiments
Using 6 g of each of the Chinese medicinal compositions obtained in examples 1 to 5, blending the mixture into paste with warm water, uniformly coating the paste on disposable eye mask paper, taking the disposable eye mask paper in a supine position, covering the eye mask paper on the positions of eyes, and taking down the disposable eye mask paper after 20 minutes.
Clinical utility: after 20 pseudomyopia adolescents of 6-16 years old are used twice a day for 1 week continuously, the asthenopia phenomena of dry eyes, sour and swollen eyes and blurred vision are obviously eliminated. The 90% naked eye vision can be improved by 1-2 rows.
The traditional Chinese medicine composition provided by the invention is convenient to use, stable in curative effect, thorough in treatment and free of any toxic and side effects, is mainly used for treating visual deterioration and myopia caused by asthenopia, and has an obvious prevention and control effect on myopia caused by asthenopia.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, various modifications and decorations can be made without departing from the principle of the present invention, and these modifications and decorations should also be regarded as the protection scope of the present invention.

Claims (6)

1. A traditional Chinese medicine composition for relieving asthenopia and treating myopia is characterized by mainly comprising the following components in parts by weight:
13-27 parts of angelica sinensis, 7-13 parts of semen cassiae, 9-15 parts of salvia miltiorrhiza, 5-15 parts of mulberry leaves, 7-13 parts of selfheal, 6-14 parts of dendrobium nobile and 8-12 parts of pearl powder.
2. The traditional Chinese medicine composition for relieving asthenopia and treating myopia according to claim 1, which is mainly prepared from the following raw materials in parts by weight:
15-25 parts of angelica sinensis, 9-11 parts of semen cassiae, 10-13 parts of salvia miltiorrhiza, 8-12 parts of mulberry leaves, 9-11 parts of selfheal, 8-12 parts of dendrobium nobile and 9-11 parts of pearl powder.
3. The traditional Chinese medicine composition for relieving asthenopia and treating myopia according to claim 2, which is mainly prepared from the following raw materials in parts by weight:
20 parts of angelica, 10 parts of cassia seed, 10 parts of salvia miltiorrhiza, 10 parts of mulberry leaf, 10 parts of selfheal, 10 parts of dendrobium and 10 parts of pearl powder.
4. The method for preparing the traditional Chinese medicine composition for relieving asthenopia and treating myopia according to any one of claims 1 to 3, which is characterized by comprising the following steps:
drying and pulverizing radix Angelicae sinensis, semen Cassiae, Saviae Miltiorrhizae radix, folium Mori, Prunellae Spica, and herba Dendrobii respectively, and mixing the pulverized powders to obtain mixture;
mixing the pearl powder and the mixture to obtain the traditional Chinese medicine composition.
5. The method for preparing a Chinese medicinal composition for relieving asthenopia and treating myopia according to claim 4, wherein the drying treatment is carried out at 40-80 ℃ for 12-36 h.
6. The method for preparing a Chinese medicinal composition for relieving asthenopia and treating myopia according to claim 5, wherein the pulverizing is performed to 80-120 mesh.
CN202011149383.0A 2020-10-23 2020-10-23 A Chinese medicinal composition for relieving asthenopia and treating myopia, and its preparation method Pending CN112089795A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115487241A (en) * 2022-09-28 2022-12-20 刘子承 Traditional Chinese medicine composition for people staying up all night, eye patch and preparation method of eye patch

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115487241A (en) * 2022-09-28 2022-12-20 刘子承 Traditional Chinese medicine composition for people staying up all night, eye patch and preparation method of eye patch
CN115487241B (en) * 2022-09-28 2024-01-30 刘子承 Traditional Chinese medicine composition and eye patch for people staying up night and preparation method thereof

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