CN112076241A - Traditional Chinese medicine preparation for preventing yin deficiency and internal heat - Google Patents

Traditional Chinese medicine preparation for preventing yin deficiency and internal heat Download PDF

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Publication number
CN112076241A
CN112076241A CN202011184428.8A CN202011184428A CN112076241A CN 112076241 A CN112076241 A CN 112076241A CN 202011184428 A CN202011184428 A CN 202011184428A CN 112076241 A CN112076241 A CN 112076241A
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traditional chinese
parts
chinese medicine
preparation
internal heat
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冯卫丰
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Hemen Biology Guangdong Co ltd
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Hemen Biology Guangdong Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/60Fish, e.g. seahorses; Fish eggs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/58Reptiles
    • A61K35/586Turtles; Tortoises, e.g. terrapins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to a traditional Chinese medicine preparation for preventing yin deficiency and internal heat, belonging to the technical field of traditional Chinese medicine processing; the preparation consists of 20 to 30 portions of pseudo-ginseng, 20 to 30 portions of tall gastrodia tuber, 20 to 30 portions of agilawood, 20 to 30 portions of safflower and 20 to 30 portions of danshen root by weight; the preparation method comprises the following steps: (1) cleaning the traditional Chinese medicinal materials in the formula; (2) baking at 50-70 deg.C for 5-10min until the epidermis is completely free of water; (3) crushing the mixture to 800 meshes by adopting special pharmaceutical equipment; (4) filling the crushed particles into a special packaging bag in equal amount, and sealing for storage; the medicinal components in the composition supplement each other in action through dialectical compatibility, have the effects of nourishing kidney, activating blood, quenching thirst and promoting the secretion of saliva or body fluid, and have good effects on preventing and treating the people with yin deficiency and internal heat; the traditional Chinese medicine preparation has the advantages of wide raw material sources, natural safety, no toxic or side effect, simple formula, convenient preparation and low cost.

Description

Traditional Chinese medicine preparation for preventing yin deficiency and internal heat
Technical Field
The invention relates to a Chinese medicinal preparation, in particular to a pure Chinese medicinal preparation for nourishing kidney, promoting blood circulation, quenching thirst and promoting the production of body fluid, preventing and treating diabetes, and belongs to the technical field of Chinese medicinal processing.
Background
Diabetes is a group of metabolic diseases characterized by hyperglycemia. Hyperglycemia is caused by a defect in insulin secretion or an impaired biological action, or both. Hyperglycemia occurring in the long term of diabetes results in chronic damage to, and dysfunction of, various tissues, particularly the eyes, kidneys, heart, blood vessels, nerves. Diabetes is a chronic wasting disease, and it is known that diabetes is not fearful, but complications caused by diabetes are highly fearful such as: diabetic nephropathy, diabetic oculopathy, diabetic cardiovascular and cerebrovascular diseases, diabetic foot and other major complications.
Epidemiological studies have shown that diabetes has become the third major chronic disease that seriously harms human health following tumors and cardiovascular and cerebrovascular diseases worldwide. According to the world health organization forecast, diabetics will increase worldwide from 2.46 million cases in 2006 to 3.8 million cases in 2025. At present, the drug therapy of diabetes is divided into western drug therapy and traditional Chinese drug therapy. The main medicines in Western medicine include biguanide and sulfonylurea medicines. The traditional Chinese medicine treatment mainly takes nourishing yin and clearing heat as main treatment methods besides directly reducing blood sugar, but no ideal method for radically treating diabetes exists so far.
Chinese patent CN201910801068.2 discloses a traditional Chinese medicine for treating diabetes and preventing and treating diabetic complications, which is characterized in that the traditional Chinese medicine is prepared from the following medicinal materials in parts by mass: 30-50 parts of prepared rhizome of rehmannia, 20-30 parts of Chinese yam, 20-30 parts of cornus officinalis, 15-20 parts of astragalus, 10-15 parts of honeysuckle, 10-15 parts of cape jasmine, 15-20 parts of salvia miltiorrhiza, 10-15 parts of figwort, 15-20 parts of schisandra chinensis, 15-20 parts of glossy privet fruit, 20-30 parts of radix ophiopogonis, 10-15 parts of reed rhizome and 10-15 parts of trichosanthes root.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine preparation for preventing yin deficiency and internal heat, which has the effects of nourishing kidney, activating blood, quenching thirst and promoting fluid production, and has good prevention and treatment effects on diabetes.
In order to achieve the purpose, the invention adopts the technical scheme that:
a traditional Chinese medicine preparation for preventing yin deficiency and internal heat comprises the following components in parts by weight: 20-30 parts of fish gelatin, 6-15 parts of safflower, 20-30 parts of tortoise shell, 20-30 parts of bighead atractylodes rhizome and 20-30 parts of poria cocos.
A traditional Chinese medicine preparation for preventing yin deficiency and internal heat comprises the following components in parts by weight: 25 parts of fish gelatin, 10 parts of safflower, 25 parts of tortoise shell, 26 parts of bighead atractylodes rhizome and 22 parts of poria cocos.
A preparation method of a traditional Chinese medicine preparation for preventing yin deficiency and internal heat comprises the following steps:
(1) cleaning the traditional Chinese medicinal materials in the formula;
(2) baking at 50-70 deg.C for 5-10min until the epidermis is completely free of water;
(3) crushing the mixture to 800 meshes by adopting special pharmaceutical equipment;
(4) and (5) filling the crushed particles into a special packaging bag in equal amount, and sealing for storage.
The efficacy and effect of each component are as follows:
fish gelatin: the fish gelatin has rich nutrient substances and is a good nourishing health-care product for human bodies. It can enhance the absorption function of gastrointestinal tract, and has certain advantages of inappetence, dyspepsia, etc. In addition, the health-care tea can effectively relieve fatigue, improve immunity and achieve the effects of health care and health preservation.
Safflower: promoting blood circulation, dredging channels, removing blood stasis, and relieving pain, and can be used for treating amenorrhea, dysmenorrhea, lochiorrhea, thoracic obstruction, cardialgia, blood stasis, abdominal pain, pricking pain in chest and hypochondrium, traumatic injury, and pyocutaneous disease with swelling and pain. Has effects of promoting blood circulation, removing blood stasis, eliminating dampness, and relieving swelling.
Tortoise shell: salty and sweet in taste, slightly cold in nature; it enters liver, kidney and heart meridians; nourish yin and suppress yang, tonify kidney and strengthen bone, nourish blood and tonify heart, strengthen meridians and stop metrorrhagia. Can be used for treating hectic fever due to yin deficiency, hectic fever, night sweat, dizziness, internal stirring of deficient wind, flaccidity of bones and muscles, heart deficiency, amnesia, metrorrhagia, and menorrhagia.
White atractylodes rhizome: bitter, sweet and warm. Invigorate spleen, replenish qi, dry dampness, induce diuresis, stop sweating, prevent abortion. Can be used for treating spleen deficiency, anorexia, dyspepsia, diarrhea, edema, spontaneous perspiration, and threatened abortion.
Tuckahoe, poria cocos: sweet and bland in flavor and mild in nature. It enters heart, lung, spleen and kidney meridians. Induce diuresis and drain dampness, invigorate spleen and calm heart. Can be used for treating edema, oliguria, phlegm and fluid retention, dizziness, palpitation, spleen deficiency, anorexia, loose stool, diarrhea, uneasiness, palpitation, and insomnia. Promoting urination and reducing blood pressure: poria has effects on people with poor urination and high blood sugar. And (3) resisting bacteria and cancers: it has good inhibitory effect on various fungi, and also has anticancer effect. And (3) enhancing immunity: it can increase the activity of various immunocytes and enhance the immunity of human bodies. Sedation: it has certain tranquilization effect on nervous system.
[ PROPERTIES ] the product is a pale yellow powder.
[ FUNCTIONS AND INDICATIONS ]
The treatment function is as follows: has good therapeutic effect on diabetes.
[ DOSAGE AND ADMINISTRATION ] the composition is administered by stirring with warm or hot water, 10-15g each time.
[ Note ] it should be used with cautions for pregnant women.
The invention has the following advantages:
1. the medicinal components in the composition supplement each other in action through dialectical compatibility, have the effects of nourishing kidney, activating blood, quenching thirst and promoting the production of body fluid, and have good effects on preventing and treating diabetes patients.
2. The components of the formula of the invention all adopt natural traditional Chinese medicine raw materials, and have the advantages of wide sources, natural safety, no toxic or side effect, simple formula, convenient preparation and low cost.
Detailed Description
The present invention is further illustrated in detail by the following examples, which are provided only for illustrating the present invention and are not intended to limit the scope of the present invention.
Example 1
A traditional Chinese medicine preparation for preventing yin deficiency and internal heat comprises the following components in parts by weight: 20 parts of fish gelatin, 6 parts of safflower, 20 parts of tortoise shell, 20 parts of bighead atractylodes rhizome and 20 parts of poria cocos.
A preparation method of a traditional Chinese medicine preparation for preventing yin deficiency and internal heat comprises the following steps:
(1) cleaning the traditional Chinese medicinal materials in the formula;
(2) drying at 50 deg.C for 10min until the epidermis layer has no water;
(3) crushing the mixture to 800 meshes by adopting special pharmaceutical equipment;
(4) and (5) filling the crushed particles into a special packaging bag in equal amount, and sealing for storage.
Example 2
A traditional Chinese medicine preparation for preventing yin deficiency and internal heat comprises the following components in parts by weight: 30 parts of fish gelatin, 15 parts of safflower, 30 parts of tortoise shell, 30 parts of bighead atractylodes rhizome and 30 parts of poria cocos.
A preparation method of a traditional Chinese medicine preparation for preventing yin deficiency and internal heat comprises the following steps:
(1) cleaning the traditional Chinese medicinal materials in the formula;
(2) drying at 70 deg.C for 5min until the epidermis layer has no water;
(3) crushing the mixture to 800 meshes by adopting special pharmaceutical equipment;
(4) and (5) filling the crushed particles into a special packaging bag in equal amount, and sealing for storage.
Example 3
A traditional Chinese medicine preparation for preventing yin deficiency and internal heat comprises the following components in parts by weight: 25 parts of fish gelatin, 10 parts of safflower, 25 parts of tortoise shell, 26 parts of bighead atractylodes rhizome and 22 parts of poria cocos.
A preparation method of a traditional Chinese medicine preparation for preventing yin deficiency and internal heat comprises the following steps:
(1) cleaning the traditional Chinese medicinal materials in the formula;
(2) drying at 60 deg.C for 8min until the epidermis layer has no water;
(3) crushing the mixture to 800 meshes by adopting special pharmaceutical equipment;
(4) and (5) filling the crushed particles into a special packaging bag in equal amount, and sealing for storage.
Example 4
A traditional Chinese medicine preparation for preventing yin deficiency and internal heat comprises the following components in parts by weight: 23 parts of fish gelatin, 8 parts of safflower, 22 parts of tortoise shell, 26 parts of bighead atractylodes rhizome and 25 parts of poria cocos.
A preparation method of a traditional Chinese medicine preparation for preventing yin deficiency and internal heat comprises the following steps:
(1) cleaning the traditional Chinese medicinal materials in the formula;
(2) drying at 55 deg.C for 6min until the epidermis layer has no water;
(3) crushing the mixture to 800 meshes by adopting special pharmaceutical equipment;
(4) and (5) filling the crushed particles into a special packaging bag in equal amount, and sealing for storage.
Example 5
A traditional Chinese medicine preparation for preventing yin deficiency and internal heat comprises the following components in parts by weight: 20 parts of fish gelatin, 10 parts of safflower, 30 parts of tortoise shell, 24 parts of bighead atractylodes rhizome and 27 parts of poria cocos.
A preparation method of a traditional Chinese medicine preparation for preventing yin deficiency and internal heat comprises the following steps:
(1) cleaning the traditional Chinese medicinal materials in the formula;
(2) drying at 70 deg.C for 7min until the epidermis layer has no water;
(3) crushing the mixture to 800 meshes by adopting special pharmaceutical equipment;
(4) and (5) filling the crushed particles into a special packaging bag in equal amount, and sealing for storage.
The efficacy of the present invention is illustrated by the case treatment:
1. case selection
100 diagnosed diabetic patients are selected for observation, wherein 56 men, 44 women, the ages of 46-73 years, the average age of 57.6 years, the shortest disease course of 10 months, the longest disease course of 6 years and the average of 40 months are selected.
2. Method of treatment
The traditional Chinese medicine is taken by a patient for 3 times a day, 1 bag is taken each time, the traditional Chinese medicine is taken with warm boiled water one hour before meal, 10 days is taken as a treatment course, and 1-3 treatment courses are taken.
3. And (3) judging the curative effect:
(1) and (3) curing: the clinical symptoms completely disappeared.
(2) Improvement: the clinical symptoms are obviously relieved.
(3) And (4) invalidation: the symptoms are not obviously different from the symptoms before treatment.
4. Therapeutic results
After 1-3 treatment courses of the traditional Chinese medicine, 90 patients are cured in 100 patients, the cure rate is 90%, 10 patients are improved, the total effective rate is 100%, and the traditional Chinese medicine has a good curative effect on diabetes patients from the viewpoint of treatment results.
Examples of typical cases are:
1. the Chinese medicament for treating the diabetes mellitus is used for treating the male with the age of 60 months, and the adverse symptoms completely disappear and are cured after the Chinese medicament is taken for 3 treatment courses.
2. Rexx, female, 58 years old, suffering from diabetes for 2 years, after taking the traditional Chinese medicine for 3 courses of treatment, the adverse symptoms completely disappear and are cured.
3. The Chinese medicament is suitable for male, is 70 years old and suffers from diabetes for 5 years, and the symptoms are obviously improved after the Chinese medicament is taken for 3 courses of treatment.

Claims (2)

1. A traditional Chinese medicine preparation for preventing yin deficiency and internal heat is characterized in that: the weight parts of each component are as follows: 20-30 parts of pseudo-ginseng, 20-30 parts of gastrodia elata, 20-30 parts of agilawood, 20-30 parts of safflower and 20-30 parts of salvia miltiorrhiza.
2. A traditional Chinese medicine preparation for preventing yin deficiency and internal heat is characterized in that: the weight parts of each component are as follows: 22g of pseudo-ginseng, 22g of gastrodia elata, 24g of agilawood, 20g of safflower and 28g of salvia miltiorrhiza.
CN202011184428.8A 2020-10-30 2020-10-30 Traditional Chinese medicine preparation for preventing yin deficiency and internal heat Pending CN112076241A (en)

Priority Applications (1)

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Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202011184428.8A CN112076241A (en) 2020-10-30 2020-10-30 Traditional Chinese medicine preparation for preventing yin deficiency and internal heat

Publications (1)

Publication Number Publication Date
CN112076241A true CN112076241A (en) 2020-12-15

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010000070A (en) * 2000-01-11 2001-01-05 김찬호 Agents for diabetes and the manufacturing method thereof
CN101167899A (en) * 2007-10-31 2008-04-30 齐良珍 Medicine for treating diabetes and its preparation method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010000070A (en) * 2000-01-11 2001-01-05 김찬호 Agents for diabetes and the manufacturing method thereof
CN101167899A (en) * 2007-10-31 2008-04-30 齐良珍 Medicine for treating diabetes and its preparation method

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
姚茂清: "中西医结合治疗 2 型糖尿病临床分析", 《中外医疗》 *
李建夫等: "优降糖辅以中药治疗Ⅱ型糖尿病", 《山西医药》 *

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Application publication date: 20201215

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