CN112057481A - Combined medicine containing glabrous sarcandra herb injection and application thereof - Google Patents

Combined medicine containing glabrous sarcandra herb injection and application thereof Download PDF

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CN112057481A
CN112057481A CN202011017107.9A CN202011017107A CN112057481A CN 112057481 A CN112057481 A CN 112057481A CN 202011017107 A CN202011017107 A CN 202011017107A CN 112057481 A CN112057481 A CN 112057481A
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injection
glabrous sarcandra
sarcandra herb
combined medicine
medicine containing
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徐新锋
裘建社
江鹏
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Guangdong Xinfeng Pharmaceutical Co ltd
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Guangdong Xinfeng Pharmaceutical Co ltd
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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Abstract

The invention belongs to the field of traditional Chinese medicines and application thereof, and provides a combined medicine containing glabrous sarcandra herb injection, which comprises 1-3mL of glabrous sarcandra herb injection, 40-60mL of physiological saline, 5-15mg of chlorpheniramine injection and 5-15mg of dexamethasone injection. The invention also combines the combined medicine of the glabrous sarcandra herb injection with various patch medicines, can cure the diseases of patients from inside to outside, combines the traditional Chinese medicine injection with the patch preparations, and leads a basic clinic to be more convenient and effective on the basis of keeping the application advantages of the injection.

Description

Combined medicine containing glabrous sarcandra herb injection and application thereof
Technical Field
The invention belongs to the field of traditional Chinese medicines and application thereof, and particularly relates to a combined medicine containing glabrous sarcandra herb injection and application thereof.
Background
Herba Pileae Scriptae (herba Pileae Scriptae, and ramulus Sambuci Williamsii) is a common Chinese medicine, is dry whole herb of sarcandra glabra (Thunb.) nakai) belonging to sarcandra of Chloranthaceae, and is collected in the 2000 th edition (part one) of Chinese pharmacopoeia. The swelling is bitter, pungent and mild in nature (not cold but not hot), and enters lung meridian, heart meridian and liver meridian. Has effects in clearing away heat, cooling blood, relieving swelling, dispersing pathogen accumulation, removing toxic materials, expelling pathogenic wind, expelling collateral obstruction, dispelling pathogenic wind and heat, promoting blood circulation, removing speckle, relieving pain, relaxing muscles and tendons, expelling pathogenic wind, removing dampness, dredging channels, and healing bone. The glabrous sarcandra herb injection has wide application and can be used for treating respiratory system diseases caused by excessive toxic heat: acute pharyngitis, herpangina, suppurative tonsillitis, bronchitis, pneumonia, etc.; digestive system diseases: gastritis, enteritis, bacillary dysentery, appendicitis, colitis, etc.; can also be used for treating urinary tract infection, prostatitis, gynecological cervicitis, and pelvic inflammatory disease; skin ulcer, cellulitis; can be used by people of all ages. The glabrous sarcandra herb injection is clinically tested and used in the middle and later stages of SARS, and has positive curative effect on senile fever type upper respiratory tract infection, pneumonia and SARS according to clinical literature. Meanwhile, the research of the pharmacological action of modern medicine shows that the glabrous sarcandra herb has obvious curative effects on resisting pathogenic microorganisms, resisting animal pathogenic microorganisms, resisting viruses, resisting tumors, immunizing, resisting gastric ulcer, promoting fracture healing and the like. In addition, the product also has analgesic, antifatigue, cold-resistant and expectorant and antiasthmatic effects; and the glabrous sarcandra herb and the extract thereof have better safety. The acute toxicity test result is practically nontoxic, and the animal sperm malformation test, the mouse bone marrow cell micronucleus test and the Ames test are all negative, and no mutation is found. The glabrous sarcandra herb is used for treating tumors (advanced pancreatic cancer, malignant tumors of digestive system, malignant tumors of nose, leukemia and the like), bacillary dysentery, fracture and various oral diseases, and achieves good treatment effect.
At present, the injection prepared from glabrous sarcandra herb has the problems of poor clarity and unstable quality.
Disclosure of Invention
In order to solve the above problems, the present invention provides a combined drug containing glabrous sarcandra herb injection, and the contents of the present invention are as follows:
the invention aims to provide a combined medicine containing glabrous sarcandra herb injection, which has the technical points that: the combined medicine containing the glabrous sarcandra herb injection comprises 1-3mL of glabrous sarcandra herb injection, 40-60mL of physiological saline, 5-15mg of chlorphenamine maleate injection and 5-15mg of dexamethasone injection.
In some embodiments of the present invention, the above-mentioned pharmaceutical composition containing glabrous sarcandra herb injection comprises 2mL of glabrous sarcandra herb injection, 50mL of physiological saline, 10mg of chlorpheniramine maleate injection and 10mg of dexamethasone injection.
In some embodiments of the present invention, the weight fraction of the normal saline in the above-mentioned one combination drug containing glabrous sarcandra herb injection is 0.8-1.0 wt%.
In some embodiments of the present invention, the specification of the dexamethasone injection in the combined drug containing glabrous sarcandra herb injection is as follows: each milliliter of dexamethasone injection contains 3-8mg of dexamethasone.
The invention provides an application of a combined medicine containing glabrous sarcandra herb injection, which has the technical points that: the combined medicine containing the glabrous sarcandra herb injection is used in combination with a cough and asthma paste for treating bronchial asthma.
The invention provides an application of a combined medicine containing glabrous sarcandra herb injection, which has the technical points that: the combined medicine containing the glabrous sarcandra herb injection is used in combination with the mass-eliminating and stasis-removing patch for treating hyperplasia of mammary glands, lobular hyperplasia, hysteromyoma and ovarian cyst.
The invention provides an application of a combined medicine containing glabrous sarcandra herb injection, which has the technical points that: the combined medicine containing the glabrous sarcandra herb injection is used in combination with an anti-inflammatory and analgesic patch for treating mastitis, dysmenorrhea, cervical spondylosis, lumbar spondylosis, scapulohumeral periarthritis and osteoarthritis.
Compared with the prior art, the invention has the beneficial effects that:
1. the formula of the combined medicine containing the glabrous sarcandra herb injection is 1-3mL of glabrous sarcandra herb injection, 40-60mL of physiological saline, 5-15mg of chlorphenamine maleate injection and 5-15mg of dexamethasone injection, the composition of the formula can effectively prevent a patient from generating anaphylactic reaction, and the combined medicine containing the glabrous sarcandra herb injection in the system has good clarity and high treatment stability.
2. The invention also combines the combined medicine of the glabrous sarcandra herb injection with various patch medicines, can cure the diseases of patients from inside to outside, combines the traditional Chinese medicine injection with the patch preparations, and leads a basic clinic to be more convenient and effective on the basis of keeping the application advantages of the injection.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below so that those skilled in the art can better understand the advantages and features of the present invention, and thus the scope of the present invention will be more clearly defined. The embodiments described herein are only a few embodiments of the present invention, rather than all embodiments, and all other embodiments that can be derived by one of ordinary skill in the art without inventive faculty based on the embodiments described herein are intended to fall within the scope of the present invention.
Example 1
A combination drug containing the glabrous sarcandra herb injection comprises 2mL of glabrous sarcandra herb injection, 50mL of normal saline (the weight fraction of the normal saline is 0.9 wt%), 5-15mg of chlorpheniramine maleate injection and 10mg of dexamethasone injection (each milliliter of the dexamethasone injection contains 6mg of dexamethasone).
The application of the combined medicine containing glabrous sarcandra herb injection and cough and asthma paste in the treatment of bronchial asthma comprises the following steps:
the method comprises the following steps: a commercially available cough and asthma plaster is applied to Ashi point or Tanzhong point of a patient and 2mL of the prepared glabrous sarcandra herb injection is injected to treat patients without cough symptoms, wherein 7-10 days is a treatment course and is taken once a day.
The method 2 comprises the following steps: a commercially available cough and asthma plaster is applied to Tiantu acupoint of patient and 1mL of the prepared combined medicine of herba Pileae Scriptae injection and 1mL of commercially available Lumbricus injection can be used for treating patients with cough symptoms, with 7-10 days as a treatment course and once a day.
The method 3 comprises the following steps: a commercially available cough and asthma plaster is applied to Danzhong point or lung acupoint (alternately applied) of a patient, and 1mL of the prepared combined medicine of the herba Pileae Scriptae injection and 1mL of the commercially available earthworm injection can be used for treating patients with cough symptoms, wherein 7-10 days is a treatment course and is taken once a day.
The clinic randomly selected 60 cases with unlimited nature and ages of 3-60 years, wherein 20 patients without cough symptoms were treated by method 1, 40 patients with cough symptoms were divided into two groups of 20 patients, one group was treated by method 2, and the other group was treated by method 3, and the treatment results are shown in table 1:
TABLE 1
Number of examples Cure of disease Cure rate
Method 1 20 20 100％
Method 2 20 20 100％
Method 3 20 20 100％
Example 2
A combined medicine containing the glabrous sarcandra herb injection comprises 1mL of glabrous sarcandra herb injection, 40mL of normal saline (the weight fraction of the normal saline is 0.8 wt%), 5mg of chlorpheniramine maleate injection and 5mg of dexamethasone injection (each milliliter of the dexamethasone injection contains 3mg of dexamethasone).
The application mode of the combined medicine containing the glabrous sarcandra herb injection and the mass-eliminating and stagnation-dissipating patch in combination for treating hyperplasia of mammary glands, lobular hyperplasia, hysteromyoma and ovarian cyst is as follows:
the method 4 comprises the following steps: a patch of commercial mass-eliminating stagnation-resolving paste is applied to Ashi point of a patient, and 1mL of the prepared glabrous sarcandra herb injection and 1mL of commercial earthworm injection are injected for treating hyperplasia of mammary glands or lobular hyperplasia, wherein 10 days is a treatment course and is taken once a day.
The method 5 comprises the following steps: a patch of commercial mass-eliminating stagnation-resolving paste is applied to the breast root acupoint of a patient, and 1mL of the prepared glabrous sarcandra herb injection and 1mL of commercial earthworm injection are used for treating hyperplasia of mammary glands and lobular hyperplasia by taking 10 days as a treatment course and twice a day.
The method 6 comprises the following steps: a patch of commercial mass-eliminating stagnation-eliminating patch is applied to Guanyuan acupoint of a patient, and 1mL of the prepared glabrous sarcandra herb injection and 1mL of commercial earthworm injection are injected together, and meanwhile, gynecological gel is used for treating hysteromyoma or ovarian cyst, wherein 10 days is a treatment course and is taken once a day.
The method 7 comprises the following steps: a patch of commercial mass-eliminating stagnation-eliminating patch is applied to the pubic symphysis of a patient, 1cm is matched with 1mL of the prepared combined medicine of the glabrous sarcandra herb injection and 1mL of commercial earthworm injection, and gynecological gel is matched with the commercial earthworm injection for treating hysteromyoma or ovarian cyst at the same time, wherein 10 days is a treatment course and is taken once a day.
80 cases with unlimited nature and 3-60 years of age were randomly selected by the outpatient clinic, wherein 40 patients had hyperplasia of mammary glands and lobular hyperplasia, and the 40 cases were divided into two groups, wherein 20 cases were treated by method 4, and the other 20 cases were treated by method 5, and the other 40 cases had hysteromyoma and ovarian cyst, and the treatment results were also divided into two groups, wherein 20 cases were treated by method 6, and the other 20 cases were treated by method 7, and the treatment results are shown in table 2:
TABLE 2
Number of examples Cure of disease Cure rate
Method 4 20 20 100％
Method 5 20 20 100％
Method 6 20 20 100％
Method 7 20 20 100％
Example 3
A combined medicine containing the glabrous sarcandra herb injection comprises 3mL of glabrous sarcandra herb injection, 60mL of normal saline (the weight fraction of the normal saline is 1.0 wt%), 15mg of chlorpheniramine maleate injection and 15mg of dexamethasone injection (each milliliter of the dexamethasone injection contains 8mg of dexamethasone).
The application mode of the combined medicine containing the glabrous sarcandra herb injection and the anti-inflammation pain-relieving plaster in the treatment of mastitis, dysmenorrhea, cervical spondylosis, lumbar spondylosis, scapulohumeral periarthritis and osteoarthritis in a combined mode is as follows:
the method 8 comprises the following steps: a commercially available anti-inflammatory analgesic patch is applied to Ashi point of patient, and 1mL of the above prepared herba Pileae Scriptae injection and 1mL of Lumbricus injection are used for treating mastitis by 10 days as a treatment course once a day.
The method 9: a commercially available anti-inflammatory analgesic patch is applied to the periphery of mammary gland of a patient and is matched with 1mL of the prepared glabrous sarcandra herb injection and 1mL of the commercially available earthworm injection for treating hyperplasia of mammary glands and lobular hyperplasia, 10 days are a course of treatment, and the course of treatment is twice a day.
The method 10 comprises the following steps: a commercially available anti-inflammatory analgesic patch is applied to the Ashi point of a patient and is matched with 1mL of the prepared glabrous sarcandra herb injection for injection and 1mL of the commercially available earthworm injection for treating dysmenorrhea, the patch starts to be applied when menstrual pain occurs, the pain is relieved after 3 to 5 days, the patch starts to be applied 5 days in advance of the next month menstrual period, the patch is applied for 5 days in succession, the pain is basically relieved, the patch is continuously applied for two months in the same way, generally 20 times, and the patch is applied in four months.
The method 11 comprises the following steps: a commercially available anti-inflammatory analgesic patch is applied to Guanyuan acupoint of a patient and is matched with a combined medicine of 1mL of the prepared glabrous sarcandra herb injection and a commercially available 1mL of earthworm injection for treating dysmenorrheal, the patch starts to be applied when the menstrual period is painful, the pain is not caused after 3 to 5 days, the patch starts to be applied 5 days in advance of the next month menstrual period, the patch is basically not painful, the patch is continuously applied for two months by the analogy, generally 20 times, and the patch is applied in four months.
The method 12 comprises the following steps: a commercially available anti-inflammatory analgesic patch is applied to Ashi point of a patient, and 1mL of the above prepared herba Pileae Scriptae injection and 1mL of Lumbricus injection are used for treating cervical spondylosis and lumbar spondylosis once a day, and 10 days is a treatment course.
Method 13: a commercially available anti-inflammatory analgesic patch is applied to both sides of cervical vertebrae or dislocation of facet joints of patients, and 1mL of the above prepared herba Pileae Scriptae injection and 1mL of Lumbricus injection are used for treating cervical spondylosis and lumbar spondylosis once a day, and 10 days is a course of treatment.
The method 14 comprises the following steps: a commercially available anti-inflammatory analgesic patch is applied to Ashi point of a patient, and 1mL of the prepared herba Pileae Scriptae injection and 1mL of Lumbricus injection are used for treating scapulohumeral periarthritis, once a day, and 10 days as a treatment course.
The method 15 comprises the following steps: a commercially available anti-inflammatory analgesic patch is applied to shoulder joint of a patient, and 1mL of the prepared herba Pileae Scriptae injection and 1mL of the commercially available Lumbricus injection are injected to treat scapulohumeral periarthritis, once a day, and 10 days as a treatment course.
The method 16 comprises the following steps: a commercially available anti-inflammatory analgesic patch is applied to Ashi point of a patient, and 1mL of the above prepared herba Pileae Scriptae injection and 1mL of Lumbricus injection are used for treating osteoarthritis once a day for 10 days as a treatment course.
The method 17: a commercially available anti-inflammatory analgesic patch is applied to the internal and external knee eyes of a patient and 1mL of the combined medicine of the glabrous sarcandra herb injection prepared above and 1mL of the earthworm injection are used for treating osteoarthritis, once a day and 10 days are a treatment course.
200 cases are randomly selected by an outpatient clinic, the nature is not limited, the age is 3-60 years, 40 cases of patients have mastitis, the 40 cases are divided into two groups, 20 cases are treated by a method 8, and the other 20 cases are treated by a method 9; there were also 40 cases with dysmenorrhea, divided into two groups, of which 20 were treated by method 10 and 20 were treated by method 11; the other 40 cases with cervical spondylosis and lumbar spondylosis are divided into two groups, wherein 20 cases are treated by the method 12, and the other 20 cases are treated by the method 13; also 40 patients with scapulohumeral periarthritis were divided into two groups, 20 of them were treated by method 14, and 20 of them were treated by method 15; there were 40 cases of osteoarthritis, also divided into two groups, of which 20 were treated with method 16 and 20 with method 17, with the results shown in table 5:
TABLE 5
Number of examples Cure of disease Cure rate
Method 8 20 20 100％
Method 9 20 20 100％
Method 10 20 20 100％
Method 11 20 20 100％
Method 12 20 20 100％
Method 13 20 20 100％
Method 14 20 20 100％
Method 15 20 20 100％
Method 16 20 20 100％
Method 17 20 20 100％
Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention, and not for limiting the protection scope of the present invention, although the present invention is described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions can be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.

Claims (7)

1. A combined medicine containing glabrous sarcandra herb injection is characterized in that: the combined medicine containing the glabrous sarcandra herb injection comprises 1-3mL of glabrous sarcandra herb injection, 40-60mL of physiological saline, 5-15mg of chlorphenamine maleate injection and 5-15mg of dexamethasone injection.
2. The combination drug of claim 1, which comprises an injection of glabrous sarcandra herb, wherein: the combined medicine containing the glabrous sarcandra herb injection comprises 2mL of glabrous sarcandra herb injection, 50mL of normal saline, 10mg of chlorphenamine maleate injection and 10mg of dexamethasone injection.
3. The combination drug according to any one of claims 1 or 2, which comprises an injection solution of glabrous sarcandra herb, wherein: the weight fraction of the normal saline is 0.8-1.0 wt%.
4. The combination drug according to any one of claims 1 or 2, which comprises an injection solution of glabrous sarcandra herb, wherein: the specification of the dexamethasone injection is as follows: each milliliter of dexamethasone injection contains 3-8mg of dexamethasone.
5. The use of a combination drug containing glabrous sarcandra herb injection according to claim 1, wherein: the combined medicine containing the glabrous sarcandra herb injection is used in combination with a cough and asthma paste for treating bronchial asthma.
6. The use of a combination drug containing glabrous sarcandra herb injection according to claim 1, wherein: the combined medicine containing the glabrous sarcandra herb injection is used in combination with the mass-eliminating and stasis-removing patch for treating hyperplasia of mammary glands, lobular hyperplasia, hysteromyoma and ovarian cyst.
7. The use of a combination drug containing glabrous sarcandra herb injection according to claim 1, wherein: the combined medicine containing the glabrous sarcandra herb injection is used in combination with an anti-inflammatory and analgesic patch for treating mastitis, dysmenorrhea, cervical spondylosis, lumbar spondylosis, scapulohumeral periarthritis and osteoarthritis.
CN202011017107.9A 2020-09-24 2020-09-24 Combined medicine containing glabrous sarcandra herb injection and application thereof Pending CN112057481A (en)

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Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
刁继红: "肿节风的实验室研究及制剂的临床应用", 《时珍国医国药》 *
陈富超等: "肿节风注射液致不良反应25例文献分析", 《中国药房》 *
陈晶等: "肿节风注射液引起过敏反应2例", 《中国医药研究》 *

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Application publication date: 20201211

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