CN112022987A - Traditional Chinese medicine preparation for treating gout - Google Patents

Traditional Chinese medicine preparation for treating gout Download PDF

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CN112022987A
CN112022987A CN202011125884.5A CN202011125884A CN112022987A CN 112022987 A CN112022987 A CN 112022987A CN 202011125884 A CN202011125884 A CN 202011125884A CN 112022987 A CN112022987 A CN 112022987A
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rhizoma
traditional chinese
chinese medicine
medicine preparation
treating
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龙步明
陈光祖
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/66Papaveraceae (Poppy family), e.g. bloodroot
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
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    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
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    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/898Orchidaceae (Orchid family)
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    • A61K36/8994Coix (Job's tears)
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    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
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    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

Abstract

The invention discloses a traditional Chinese medicine preparation for treating gout, which is characterized by being prepared from 15 g of dactylicapnos root, 15 g of lamiophlomis rotata, 15 g of rhizoma anemones raddeanae, 15 g of rhizoma homalomenae, 15 g of rhizoma smilacis glabrae, 12 g of rhizoma dioscoreae hypoglaucae, 15 g of clematis chinensis, 15 g of peach kernel, 10 g of safflower, 15 g of herba lycopi, 15 g of rhizoma alismatis, 15 g of coix seed, 20 g of plantain herb, 25 g of sweet wormwood herb, 20 g of rhizoma atractylodis, 20 g of rhizoma pleionis, 10 g of arisaema cum bile and 15 g of mahonia fortunei, wherein the traditional Chinese medicines are taken, 1500ml of water is added, decocted for 30 minutes by slow fire. Compared with the prior art, the formula of the invention has the effects of expelling wind, relieving pain, promoting blood circulation, removing obstruction in channels, nourishing liver and kidney, breaking blood, removing blood stasis, promoting blood circulation and resolving masses. The medicines are reasonably compatible, treat both symptoms and root causes, are suitable for pathogenesis, and have better effect of treating cerebral thrombosis. The formula of the invention has rich medicine sources, low price and convenient taking, and is easy to be accepted by patients.

Description

Traditional Chinese medicine preparation for treating gout
Technical Field
The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine preparation for treating gout.
Background
Gout is a metabolic rheumatism which is difficult to cure and easy to relapse. The pathogenesis of gout is closely related to purine metabolic disorder and reduced uric acid excretion. Gout is characterized by high uric acid, characteristic repeated attack of acute arthritis, tophus, chronic arthritis and joint deformity, and renal interstitial nephritis and uric acid renal calculus caused by kidney involvement. The increase of blood uric acid can induce a plurality of tissue injuries, and acute gouty arthritis is called wind. With the improvement of living standard and the unreasonable change of dietary structure in more than 10 years, the incidence rate of gout in China shows a trend of increasing day by day, and the gout poses a potential threat to the health of people.
At present, western medicine treatment for gout is symptomatic treatment and is not beneficial to overall treatment, and the western medicine has a plurality of toxic and side effects and adverse reactions.
The traditional Chinese medicine for treating gout in China has unique advantages, can regulate the whole body, treat both symptoms and root causes, prevent and treat diseases simultaneously, has better curative effect shown by clinical and experimental researches, is not easy to relapse, and has no obvious toxic or side effect. Moreover, modernization of traditional Chinese medicine is a historical development need. Therefore, the research and development of the traditional Chinese medicine preparation for preventing and treating gout are significant
Disclosure of Invention
In view of the above, the invention provides a traditional Chinese medicine preparation for treating gout, which has the advantages of quick response, no toxic or side effect, and capability of treating or effectively relieving gout symptoms.
In order to achieve the purpose, the invention provides the following technical scheme:
a traditional Chinese medicine preparation for treating gout is characterized by being prepared from 15 g of dactylicapnos root, 15 g of lamiophlomis rotata, 15 g of rhizoma anemones raddeanae, 15 g of rhizoma homalomenae, 15 g of rhizoma smilacis glabrae, 12 g of rhizoma dioscoreae hypoglaucae, 15 g of radix clematidis, 15 g of peach kernel, 10 g of safflower, 15 g of herba lycopi, 15 g of rhizoma alismatis, 15 g of coix seed, 20 g of plantain herb, 25 g of sweet wormwood herb, 20 g of rhizoma atractylodis, 20 g of rhizoma pleionis, 10 g of arisaema cum bile and 15 g of mahonia, 1500ml of water is added into the traditional Chinese medicines, the traditional Chinese medicines are decocted for 30 minutes by slow fire, dregs are.
Preferably, in the traditional Chinese medicine preparation for treating gout, the liquid medicine is used for 1-2 times three times a day.
The effects of the components in the invention are as follows:
radix dactylicapni: pungent, slightly bitter, cool in nature, toxic. Diminish inflammation, stop pain, stop bleeding and reduce blood pressure. Can be used for treating various pains, traumatic injury, hypertension, and traumatic hemorrhage by external application. "yunnan Chinese herbal medicine selection" year: "stop bleeding". It is indicated for metrorrhagia and postpartum excessive bleeding.
Lamiophlomis rotata, the name of traditional Chinese medicine. Is root, rhizome or whole plant of Lamiophlomis rotate (Benth.) kudo of Labiatae. Has effects of promoting blood circulation, removing blood stasis, and relieving swelling and pain. Can be used for treating traumatic injury, arthralgia and myalgia, joint swelling and pain, dysmenorrhea, and metrorrhagia.
Rhizoma anemones Raddeanae is the dried rhizome of Anemone raddeanearegel which is a plant of Ranunculaceae. Mainly distributed in the three provinces of northeast and Shandong, Hebei and Shanxi, etc., with the highest yield in Jilin province. The herbs are collected in summer, removed of residual stem and fibrous root, and dried in the sun. The herb is first recorded in Ben Cao Pin Hui Jing Yao (materia Medica of materia Medica) of Liu Wen Tai of Ming dynasty. Has the efficacies of dispelling wind and eliminating dampness and eliminating carbuncle and swelling. As early as the Qing Dynasty, Wang Xugao 'Ding-ai san' used for treating breast cancer with two tips. At present, the traditional Chinese medicine composition is clinically used for treating wind-cold-dampness arthralgia, hand and foot contracture, bone joint pain, carbuncle, cellulitis and gall. It is mainly used as the raw material of the famous Chinese patent medicines "Huoluodan" and "zaizao pill", because it is usually combined with other medicines, not used singly. The product is rich in triterpenoid saponins, wherein the triterpenoid saponin anemonin A is one of the main anti-tumor effective components.
Obscured homalomena rhizome: dispel wind-damp, strengthen tendons and bones, and stop arthralgia, it can dispel wind-damp, strengthen tendons and bones, and stop arthralgia, especially good at treating spasm and numbness of lower limbs.
Rhizoma Smilacis Glabrae has effects of dispelling toxic gas, clearing heat and promoting diuresis.
Coicis semen has effects of warming spleen and stomach, dispelling cold, and invigorating qi and blood.
The yam rhizome has obvious effect of treating the pain of waist and knees.
The Chinese medicine is prepared by the following steps: dispelling wind and removing dampness; promoting blood circulation and removing obstruction in channels; detoxify and dissipate nodulation.
Semen Persicae has effects of promoting blood circulation and removing blood stasis.
Safflower, name of Chinese medicine. Is dried flower of Carthamustatin flower L. Collected in the shade or dried in the sun when the flowers turn yellow and red in summer. The cultivation is widely carried out all over the country. Has the functions of promoting blood circulation to restore menstrual flow, eliminating blood stasis and relieving pain. Can be used for treating amenorrhea, dysmenorrhea, lochiorrhea, abdominal mass, thoracic obstruction, cardialgia, abdominal pain due to blood stasis, pricking pain in chest and hypochondrium, traumatic injury, and pyocutaneous disease with swelling and pain.
Herba Lycopi is bitter in taste and slightly warm in nature, and has effects of promoting blood circulation, removing blood stasis, and resolving stagnation for menoxenia and amenorrhea.
Rhizoma alismatis: sweet in taste; diluting; is cold in nature. Returning to the kidney; the bladder channel. Clearing damp and promoting diuresis; purging heat and treating stranguria.
Plantain herb: cold in nature and sweet in taste. It enters liver meridian, kidney meridian, lung meridian and small intestine meridian. Clear heat and induce diuresis, dispel phlegm, cool blood and remove toxicity. Belongs to the diuresis and stranguria treatment drugs classified under the diuresis and dampness eliminating drugs. Can be used for treating edema, oliguria, pyretic stranguria, pain, summer-heat, damp diarrhea, dysentery, phlegm heat, cough, hematemesis, epistaxis, carbuncle, swelling, and sore. The pharmacological test result shows that the plantain herb decoction has the functions of eliminating phlegm, relieving cough and resisting fungi. Has diuretic effect; has antitussive, antiasthmatic, and expectorant effects; resisting pathogenic microorganism.
Sweet wormwood herb is a good medicine for clearing heat, cooling blood and relieving steaming, and can clear deficiency heat, cool blood, remove steaming and check malaria. Can be used for treating fever due to summer-heat, fever due to yin deficiency, night fever with early coolness, hectic fever due to yin deficiency, malaria with cold-heat, and jaundice due to damp-heat. The herb is bitter and cold in flavor and clear heat, pungent and fragrant in flavor and good at dispersing yin and latent heat to the exterior, so it is the key herb for fever due to yin deficiency, and has the actions of relieving summer-heat and checking malaria. It can be used for treating exogenous summer heat, fever and polydipsia. Liuhongming, etc. are separated from herba Artemisiae Annuae by ethanol extraction to obtain two coumarin components, 6-methoxy-7-hydroxycoumarin (hyoscyamus) and coumarin.
Rhizoma Atractylodis has effects of eliminating dampness, invigorating spleen, eliminating turbid pathogen, and relieving pain.
Pseudobulbus Cremastrae Seu pleiones is pseudobulb of Rhododendron simsii and Pleiones bulbocodioides of Orchidaceae. The pseudobulb grows on the mountain ditch rock, is dug in the month, is removed of stem leaves and fibrous roots, is cleaned and dried in the sun to be used as the raw material of the invention. According to the pharmacopoeia, the medicine has sweet, slightly pungent, cold and slightly toxic taste, and has the pharmacological effects of detumescence, mass resolving and phlegm reducing.
Arisaema cum bile: cool, bitter and slightly pungent, entering lung, liver and spleen meridians, clearing heat and resolving phlegm, calming endogenous wind and arresting convulsion.
Mahonia is an evergreen shrub or small arbor belonging to the family Berberidaceae (Berberidaceae) and genus Mahonia, and is mostly distributed in the south of Yangtze river in China. Mahonia has both ornamental and medicinal values, and has effects of clearing heat and detoxicating, nourishing yin and strengthening body, and is used for long time by folk medicine. Mahonia root, stem and leaf can be used as medicine, and its dried stem is the medicinal part of Mahonia collected in the pharmacopoeia of China (2015 edition). Modern pharmacology indicates that the plant has multiple biological activities of antibiosis, anti-inflammation, antioxidation, anti-tumor and the like, and is mainly used for treating eczema and psoriasis clinically.
According to the technical scheme, compared with the prior art, the formula disclosed by the invention has the effects of dispelling wind, relieving pain, promoting blood circulation, removing meridian obstruction, nourishing liver and kidney, breaking blood, removing blood stasis, promoting blood circulation and resolving masses. The medicines are reasonably compatible, treat both symptoms and root causes, are suitable for pathogenesis, and have better effect of treating cerebral thrombosis. The formula of the invention has rich medicine sources, low price and convenient taking, and is easy to be accepted by patients.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example (b):
a traditional Chinese medicine preparation for gout is characterized in that the traditional Chinese medicine preparation is prepared by 15 g of dactylicapnos root, 15 g of lamiophlomis rotata, 15 g of rhizoma anemones raddeanae, 15 g of rhizoma homalomenae, 15 g of rhizoma smilacis glabrae, 12 g of rhizoma dioscoreae hypoglaucae, 15 g of radix clematidis, 15 g of peach kernel, 10 g of safflower, 15 g of herba lycopi, 15 g of rhizoma alismatis, 15 g of semen coicis, 20 g of plantain herb, 25 g of sweet wormwood herb, 20 g of rhizoma atractylodis, 20 g of rhizoma pleionis, 10 g of arisaema cum bile and 15 g of mahonia, 1500ml of water is added into the traditional Chinese medicines, the traditional Chinese medicines are decocted for 30 minutes; when in use, the lotion is used for three times a day and 1 to 2 times a day.
The traditional Chinese medicinal materials in the formula of the preparation are all medicinal materials loaded in the national pharmacopoeia, and according to the introduction of the pharmacopoeia, the various medicines are safe and have no toxic or side effect.
The taking method comprises the following steps:
three times a day, 1-2 liquid medicines each time.
Attention points for taking medicine:
1, during taking, wine, strong tea, coffee and other drinks are prohibited.
2, spicy food, animal internal organs and food containing high purine content are avoided.
The using effect data of the traditional Chinese medicine preparation for treating gout
Since the product is developed, the number of users reaches 120, and clinical application shows 108 cases with 12 cases with 100% of effective rate.
Typical cases are:
1. a certain king is a male, is 49 years old, is willing to smoke and drink at ordinary times, is addicted to animal viscera food, suffers from gout for 3 years, has red swelling and pain of toe joints, has uric acid higher than normal value, takes effect on the day of taking, relieves pain within 6-7 hours, can reduce swelling within 24 hours, and has satisfactory curative effect.
2. Somebody Guo, 48 years old, male. In 2005, the joint had become deformed and was unable to move, and the joints of hands and feet were often red, swollen and painful. After a plurality of hospitals are seen for a few years, symptoms are relieved after the treatment of a plurality of medicines, and relapse and aggravation are realized after a while. After introduction, the traditional Chinese medicine preparation is tried out, the pain is relieved in one course of treatment, after the traditional Chinese medicine preparation is continuously taken for 2 courses of treatment, the pain disappears, the red and swollen joints disappear, the rehabilitation is performed after the treatment lasts for three months, and the relapse does not occur.
3. A certain Liu is a male, aged 54 years old, manages cadre, suffers from gout for 4 years, and has the symptoms of toe joint swelling and pain, soreness and weakness of waist and knees, resistance reduction, high blood fat, high blood pressure and high blood sugar, and the symptoms disappear after the pill is taken for one month, so the mental state is better.
The embodiments in the present description are described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same and similar parts among the embodiments are referred to each other. The device disclosed by the embodiment corresponds to the method disclosed by the embodiment, so that the description is simple, and the relevant points can be referred to the method part for description.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims (2)

1. A traditional Chinese medicine preparation for treating gout is characterized by being prepared from 15 g of dactylicapnos root, 15 g of lamiophlomis rotata, 15 g of rhizoma anemones raddeanae, 15 g of rhizoma homalomenae, 15 g of rhizoma smilacis glabrae, 12 g of rhizoma dioscoreae hypoglaucae, 15 g of radix clematidis, 15 g of peach kernel, 10 g of safflower, 15 g of herba lycopi, 15 g of rhizoma alismatis, 15 g of coix seed, 20 g of plantain herb, 25 g of sweet wormwood herb, 20 g of rhizoma atractylodis, 20 g of rhizoma pleionis, 10 g of arisaema cum bile and 15 g of mahonia, 1500ml of water is added into the traditional Chinese medicines, the traditional Chinese medicines are decocted for 30 minutes by slow fire, dregs are.
2. The traditional Chinese medicine preparation for treating gout according to claim 1, which is used for 1-2 liquid medicines three times a day.
CN202011125884.5A 2020-10-20 2020-10-20 Traditional Chinese medicine preparation for treating gout Pending CN112022987A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107158285A (en) * 2017-06-22 2017-09-15 巫献 It is a kind of to treat Chinese medicine preparation of gout and preparation method thereof
CN109674960A (en) * 2019-01-25 2019-04-26 赵廷忠 A kind of preparation of water seedling Chinese herbal treatment gout

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107158285A (en) * 2017-06-22 2017-09-15 巫献 It is a kind of to treat Chinese medicine preparation of gout and preparation method thereof
CN109674960A (en) * 2019-01-25 2019-04-26 赵廷忠 A kind of preparation of water seedling Chinese herbal treatment gout

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Application publication date: 20201204