CN112006166A - Serine feed additive for improving survival rate and growth speed of piglets and application thereof - Google Patents
Serine feed additive for improving survival rate and growth speed of piglets and application thereof Download PDFInfo
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- CN112006166A CN112006166A CN202010714020.0A CN202010714020A CN112006166A CN 112006166 A CN112006166 A CN 112006166A CN 202010714020 A CN202010714020 A CN 202010714020A CN 112006166 A CN112006166 A CN 112006166A
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
- A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/60—Feeding-stuffs specially adapted for particular animals for weanlings
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Abstract
The invention discloses a serine feed additive for improving the survival rate and the growth speed of piglets and application thereof. The feed additive comprises serine, compound yeast powder and carrier puffed soybean powder, and preferably comprises 20-80 parts by weight of serine, 10-40 parts by weight of compound yeast powder and 10-40 parts by weight of carrier puffed soybean powder. The feed additive is suitable for being added into daily ration of weaned pigs, is used for helping to enhance disease resistance and immunity of the piglets, improves the utilization rate of the feed and the survival rate of the piglets, promotes the healthy growth of the piglets and relieves weaned syndrome of the piglets, thereby improving the breeding benefit of the piglets.
Description
Technical Field
The application belongs to the technical field of animal nutrition, and particularly relates to a serine feed additive for improving the survival rate and the growth speed of piglets and application thereof.
Background
With the large-scale development of the pig industry, the piglets become older and older in the days of early weaning in production. However, piglets are susceptible to weaning emergency syndrome after weaning, and have the problems of reduced immunity function, high mortality rate, high morbidity and the like.
The disease resistance of the piglets can be enhanced by using antibiotics in the growth stage of the piglets, but the immunity of the piglets is reduced by using the antibiotics for a long time. How to effectively solve the problem of piglet weaning emergency syndrome is still a difficult problem for farmers.
Disclosure of Invention
The invention aims to provide the serine feed additive capable of improving the survival rate and the growth speed of piglets and the application thereof, so as to help improve the feed utilization rate in the breeding process of the piglets, enhance the autoimmunity and the resistance of the piglets to diseases, improve the survival rate of the piglets, promote the healthy growth of the piglets and relieve the weaning emergency syndrome of the piglets.
In one aspect, the present invention provides a serine feed additive capable of increasing survival rate and growth rate of piglets, comprising serine, composite yeast powder and a carrier expanded soybean powder.
Preferably, the feed additive comprises 20-80 parts of serine, 10-40 parts of compound yeast powder and 10-40 parts of carrier puffed soybean powder by weight.
Preferably, the feed additive comprises 20 parts of serine, 40 parts of composite yeast powder and 40 parts of carrier puffed soybean powder by weight.
Preferably, the feed additive comprises, by weight, 45 parts of serine, 19 parts of complex yeast powder and 36 parts of carrier puffed soybean powder.
Preferably, the feed additive comprises, by weight, 62 parts of serine, 21 parts of complex yeast powder and 17 parts of carrier puffed soybean powder.
Preferably, the feed additive comprises, by weight, 80 parts of serine, 10 parts of complex yeast powder and 10 parts of carrier puffed soybean powder.
Preferably, the content of the yeast in the composite yeast powder is more than or equal to 1.0 multiplied by 1010cfu/g。
In another aspect, the invention provides the use of a feed additive as described above, which is incorporated into an animal's ration prior to feeding the animal.
Preferably, the animal is a weaned piglet.
Preferably, the feed additive is incorporated into the animal ration in an amount of 1 wt% of the animal ration.
The feed additive is suitable for being added into the daily ration of the piglets, can help to enhance the disease resistance and the immunity of the piglets, improve the utilization rate of the feed and the survival rate of the piglets, promote the healthy growth of the piglets and relieve the weaning syndrome of the piglets, thereby improving the breeding benefit of the piglets.
Detailed Description
The present invention is described in detail below with reference to specific embodiments so that the advantages and features of the present invention can be more easily understood by those skilled in the art, thereby making the scope of the present invention more clearly defined.
Serine is a non-essential amino acid that plays a role in the metabolism of fats and fatty acids and in muscle growth. It is a precursor for the synthesis of purines, thymines, choline and is one of the main components of phospholipids, and is very important for maintaining the health of animals. The compound yeast powder is rich in nutrient components and physiological active substances generated by yeast. The feed additive for the piglets provided by the invention integrates the nutrition of serine and the nutrition and physiological active substances in the compound yeast powder, and adopts the puffed soybean meal as a carrier. Can improve the utilization rate of feed in the process of breeding the piglets, enhance the autoimmunity and the resistance to diseases of the piglets, improve the survival rate of the piglets, promote the healthy growth of the piglets and relieve the weaning emergency syndrome of the piglets, thereby improving the benefit of the piglet breeding industry.
The piglet feed additive of the present invention will be further described with reference to the following specific examples.
Example one
The raw materials of the feed additive in the embodiment comprise 20 parts of serine, 40 parts of compound yeast powder and 40 parts of carrier puffed soybean powder by weight. The composite yeast powder contains Candida utilis, cerevisiae Fermentum, yeast hydrolysate and zymosan, wherein the content of yeast is not less than 1.0 × 1010cfu/g。
Weighing serine, compound yeast powder and non-mildewed and non-caked puffed soybean meal, sequentially adding the materials into a mixing container under the stirring state, and uniformly stirring and mixing to obtain the feed additive 1.
Example two
The raw materials of the feed additive in the embodiment comprise, by weight, 45 parts of serine, 19 parts of compound yeast powder and 36 parts of carrier puffed soybean powder. The composite yeast powder contains Candida utilis, cerevisiae Fermentum, yeast hydrolysate and zymosan, wherein the content of yeast is not less than 1.0 × 1010cfu/g。
Weighing serine, compound yeast powder and non-mildewed and non-caked puffed soybean meal, sequentially adding into a mixing container under stirring, and uniformly stirring and mixing to obtain the feed additive 2.
EXAMPLE III
The raw materials of the feed additive in the embodiment comprise 62 parts of serine, 21 parts of compound yeast powder and 17 parts of carrier puffed soybean powder by weight. The composite yeast powder contains Candida utilis, cerevisiae Fermentum, yeast hydrolysate and zymosan, wherein the content of yeast is not less than 1.0 × 1010cfu/g。
Weighing serine, compound yeast powder and non-mildewed and non-caked puffed soybean powder, sequentially adding into a mixing container under stirring, and uniformly stirring and mixing to obtain the feed additive 3.
Example four
The raw materials of the feed additive in the embodiment comprise, by weight, 80 parts of serine, 10 parts of compound yeast powder and 10 parts of carrier puffed soybean powder. The composite yeast powder contains Candida utilis, cerevisiae Fermentum, yeast hydrolysate and zymosan, wherein the content of yeast is not less than 1.0 × 1010cfu/g。
Weighing serine, compound yeast powder and non-mildewed and non-caked puffed soybean meal, sequentially adding into a mixing container under stirring, and uniformly stirring and mixing to obtain the feed additive 4.
Test one: influence of feed additive on growth and anti-stress capability of weaned piglets
150 duroc, Changbai and approximately gram weaned piglets which are good in development, strong in appetite, healthy, similar in genetic basis and similar in initial weight and are 45 days old are selected and randomly divided into 5 groups including a control group and 4 test groups, each group is provided with 3 repetitions, each repetition is provided with 10 repetitions, and each half of a male parent and a female parent is provided with half of the total weight of the weaned piglets. The piglets in each group were fed with the corresponding diets, respectively, wherein the control group was fed with a conventional basal diet for piglets, and the diets of the 4 test groups were basal diets for piglets incorporating 1 wt% of the corresponding feed additives. The basal diet components of the piglets are prepared with the nutrition requirement standard of 8-20kg weight weaned piglets in the nutrition level reference pig feeding standard (NY/T65-2004).
All the piglets are raised in the same pigsty and are separated from each other. The feed additive is fully mixed in the feed for feeding, the feeding is carried out for 3 times (7:00, 12:00 and 17:00) every day, and each repeated 10 piglets fed in the same fence eat together, and are fed with free food and drinking water. The temperature in the pigsty is kept at 26-32 ℃, and the temperature and the relative humidity are measured and recorded at 7:00, 12:00 and 16:30 every day.
After 3 days of pre-feeding, a performance period of 43 days of the official trial was followed, all piglets were weighed on empty stomach on day 1 from the start and on the end of the official trial. And observing and recording the health conditions of all the test piglets every day, accurately recording the feed intake and the death condition of each group of test piglets, and calculating the average daily gain, the feed-weight ratio, the diarrhea rate and the death rate of each group of piglets after the test is finished. The results are shown in Table 1.
TABLE 1
As can be seen from the data in table 1, the average daily gain of 4 piglets fed with the feed additive was increased by 14.49%, 21.03%, 23.36% and 25.24% respectively, compared to the control group; the average material weight ratio is respectively reduced by 6.85%, 10.29%, 18.86% and 21.14%; the average diarrhea rate is respectively reduced by 65.52%, 62.32%, 56.28% and 66.50%; the death rate of piglets is respectively reduced by 13.3%, 10% and 13.3%. Therefore, the prepared feed additives 1 to 4 can promote the growth of weaned piglets, improve the utilization rate of the feed, reduce the diarrhea rate of the piglets, and further improve the survival rate of the piglets.
On days 14, 28 and 42 of the test, 3 piglets are randomly selected at each repetition, blood is collected in the anterior vena cava for 8mL, after blood coagulation, centrifugation is carried out for 10min at the temperature of 4 ℃ and at the speed of 1400r/min, and serum is collected and stored for later use at the temperature of minus 20 ℃. The Creatine Kinase (CK) activity and Glucose (GLU) content in serum were determined. The results are shown in Table 2.
TABLE 2
As can be seen from the data in table 2, the serum content of Creatine Kinase (CK) was significantly reduced, but the Glucose (GLU) content was not significantly changed in the 4 groups of piglets fed with the feed additive, compared to the control group. Creatine Kinase (CK) and Glucose (GLU) are two important indexes for judging the stress of weaned pigs. CK is mainly present in cardiac muscle, and the content of blood serum of piglets is low when the piglets are normal. It is only when the body is diseased or the body tissues are damaged, it is elevated. When weaned piglets are stressed, the content of CK in serum is rapidly increased, GLU generated by starch digestion is less, the concentration of GLU in serum is also reduced, and the energy utilization rate is reduced. The results in table 2 show that the prepared feed additives 1 to 4 can reduce the weaning stress reaction of piglets, relieve the weaning stress syndrome of piglets and promote the healthy growth of weaned piglets.
The above description is only an embodiment of the present invention, and not intended to limit the scope of the present invention, and all equivalent structural changes made by using the contents of the present specification, or any other related technical fields directly or indirectly, are included in the scope of the present invention.
Claims (10)
1. A serine feed additive for increasing survival rate and growth speed of piglets comprises serine, compound yeast powder and puffed soybean powder as carrier.
2. The feed additive of claim 1, wherein the feed additive comprises 20-80 parts by weight of the serine, 10-40 parts by weight of the complex yeast powder, and 10-40 parts by weight of the carrier expanded soybean meal.
3. The feed supplement of claim 2, wherein the feed supplement comprises 20 parts by weight of the serine, 40 parts by weight of the complex yeast powder, and 40 parts by weight of the carrier expanded soybean meal.
4. The feed supplement of claim 2, wherein the feed supplement comprises, by weight, 45 parts of the serine, 19 parts of the complex yeast powder, and 36 parts of the carrier expanded soybean meal.
5. The feed supplement of claim 2, wherein the feed supplement comprises, by weight, 62 parts of the serine, 21 parts of the complex yeast powder, and 17 parts of the carrier expanded soybean meal.
6. The feed supplement of claim 2, wherein the feed supplement comprises 80 parts by weight of the serine, 10 parts by weight of the complex yeast powder, and 10 parts by weight of the carrier expanded soybean meal.
7. A process as claimed in any one of claims 1 to 6The feed additive is characterized in that the content of microzyme in the composite yeast powder is more than or equal to 1.0 multiplied by 1010cfu/g。
8. Use of a feed additive according to any one of claims 1 to 7 which is incorporated into the ration of an animal prior to feeding the animal.
9. The use of claim 8, wherein the animal is a weaned piglet.
10. The use of claim 8, wherein the feed additive is incorporated into the animal ration in an amount of 1 wt% of the animal ration.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010714020.0A CN112006166A (en) | 2020-07-22 | 2020-07-22 | Serine feed additive for improving survival rate and growth speed of piglets and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010714020.0A CN112006166A (en) | 2020-07-22 | 2020-07-22 | Serine feed additive for improving survival rate and growth speed of piglets and application thereof |
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| Publication Number | Publication Date |
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| CN112006166A true CN112006166A (en) | 2020-12-01 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202010714020.0A Pending CN112006166A (en) | 2020-07-22 | 2020-07-22 | Serine feed additive for improving survival rate and growth speed of piglets and application thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112890016A (en) * | 2021-02-20 | 2021-06-04 | 湖南师范大学 | Animal nutrient solution for promoting growth of suckling piglets and preparation method and application thereof |
| CN113040281A (en) * | 2021-03-22 | 2021-06-29 | 湖南师范大学 | Preparation capable of improving secretion of antimicrobial peptide in intestinal tract of piglet and application thereof |
Citations (4)
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| CN102696874A (en) * | 2012-06-22 | 2012-10-03 | 铁岭东大集团东大牧业有限公司 | Suckling pig creep feed |
| CN106578521A (en) * | 2016-12-13 | 2017-04-26 | 渠县金穗农业科技有限公司 | Pig feed formula |
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| CN107594128A (en) * | 2017-11-06 | 2018-01-19 | 朱喜玲 | A kind of lily feed that can improve animal immunizing power and preparation method thereof |
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2020
- 2020-07-22 CN CN202010714020.0A patent/CN112006166A/en active Pending
Patent Citations (4)
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| CN102696874A (en) * | 2012-06-22 | 2012-10-03 | 铁岭东大集团东大牧业有限公司 | Suckling pig creep feed |
| CN106578521A (en) * | 2016-12-13 | 2017-04-26 | 渠县金穗农业科技有限公司 | Pig feed formula |
| CN106721021A (en) * | 2016-12-30 | 2017-05-31 | 长春禾丰饲料有限责任公司 | A kind of piglet antibiotic-free feed and preparation method thereof |
| CN107594128A (en) * | 2017-11-06 | 2018-01-19 | 朱喜玲 | A kind of lily feed that can improve animal immunizing power and preparation method thereof |
Non-Patent Citations (2)
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| 伍国耀等: ""猪对"非必需氨基酸"的营养需要"", 《饲料工业》 * |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112890016A (en) * | 2021-02-20 | 2021-06-04 | 湖南师范大学 | Animal nutrient solution for promoting growth of suckling piglets and preparation method and application thereof |
| CN113040281A (en) * | 2021-03-22 | 2021-06-29 | 湖南师范大学 | Preparation capable of improving secretion of antimicrobial peptide in intestinal tract of piglet and application thereof |
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