CN111991296A - Preparation method of acne-removing essence - Google Patents

Preparation method of acne-removing essence Download PDF

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CN111991296A
CN111991296A CN202010967177.4A CN202010967177A CN111991296A CN 111991296 A CN111991296 A CN 111991296A CN 202010967177 A CN202010967177 A CN 202010967177A CN 111991296 A CN111991296 A CN 111991296A
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acne
preparation
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removing essence
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刘圆霖
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • A61K36/515Gentiana
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

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  • Health & Medical Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
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  • Microbiology (AREA)
  • Botany (AREA)
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  • Alternative & Traditional Medicine (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
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Abstract

The preparation method of the acne-removing essence is characterized by comprising the following steps: soaking the medicinal materials, namely soaking the medicinal materials which comprise the following components in parts by weight in water: 15-70 parts of honeysuckle, 2-50 parts of gentian, 6-30 parts of mint and 2-10 parts of moutan bark; distilling the substances by using a distilling device, wherein the distilling temperature is 60-80 ℃ to obtain a distilled extract; ③ adding a humectant into the distilled extract to obtain the acne-removing essence. Honeysuckle is used as a monarch, gentian is used as a minister, mint and tree peony bark are used as an assistant and guide, and the four medicines are used together in a matching way, so that the effect is strong, and the honeysuckle flower distillate is distilled into distillate and has good absorption.

Description

Preparation method of acne-removing essence
Technical Field
The invention relates to essence, in particular to a preparation method of essence for treating acne, eczema, furunculosis, skin inflammation, allergy and cosmetic allergy.
Background
Acne, which occurs well on the face and chest and back, is an acute or chronic inflammation of the sebaceous glands of the hair follicle. Commonly known as acne, comedo and pimple, are common and frequently encountered diseases in dermatology. Acne is a multi-etiology disease, and the pathogenesis of acne is not completely understood at present. It is possible that sebum secretion is increased due to increase of androgenic hormones in puberty, especially increase of dihydrotestosterone, and meanwhile keratotic embolism of pilosebaceous ducts, so that sebum is accumulated in hair follicles to form lipid plugs, so-called comedo blackheads or whiteheads. Acne bacteria in hair follicles multiply faster in a nutrient-rich and relatively anoxic environment and produce lysolipases, proteolytic enzymes and hyaluronidase. Lipolytic enzymes break down triglycerides in sebum into free fatty acids. Free fatty acids, proteolytic enzymes and hyaluronidase can damage the hair follicle wall, allowing the hair follicle contents to enter the dermis, causing an inflammatory response in the pilosebaceous follicles. In addition, endopollicular acne propionibacterium; lack or relative insufficiency of trace elements in the body, particularly zinc. Inheritance may also have some relationship.
The traditional Chinese medicine considers that the acne is caused by exuberant internal heat and external wind evil, or is characterized by improper diet and overeating of fat, sweet and thick flavor, and the stomach heat is steamed upwards; it can also be indicated for irregular menstruation, stasis and heat transformation. But it is classified into lung heat, blood heat, liver heat, yin deficiency and internal heat. Skin lesions such as pustules are caused by wind-heat and toxic heat. Cystic acne, acne conglobata and other inflammatory symptoms are not obvious, and the chronic process is the symptom of cold sores and cold ulcers. In addition, cicatricial acne can be caused by qi stagnation and blood stasis.
Eczema is a common inflammatory skin disease of epidermis and dermis superficial layer caused by various internal and external factors, and is generally considered to have a certain relation with allergic reaction. The clinical manifestations of the medicine are characterized by symmetry, exudation, pruritic dermatosis, polymorphism and recurrence. Eczema is a skin disease which is easy to relapse, belongs to a skin disease which is difficult to treat, and is accompanied by severe pruritus, so that the work and the study of people are often influenced, the life quality of patients is reduced, and treatment needs a relapsing special drug, such as a drug containing a healthy and clean skin component, and the allergic inflammatory skin disease is also characterized by the diversity and the symmetrical distribution of skin rash, repeated attack of severe pruritus and easy development into chronic skin disease. It can occur at any part of any age and in any season, but often recurs or aggravates in winter, has exudation tendency, has chronic course and is easy to recur.
However, the effect of the existing medicament for treating acne and eczema is not obvious, and the symptoms are easy to relapse.
Disclosure of Invention
The invention aims to solve the technical problem of providing a preparation method of an acne-removing essence which has good curative effect on eczema and acne and no side effect.
The technical scheme adopted by the invention for solving the technical problems is as follows: the preparation method of the acne-removing essence is characterized by comprising the following steps:
soaking the medicinal materials, namely soaking the medicinal materials which comprise the following components in parts by weight in water:
Figure BDA0002682776460000021
distilling the substances by using a distilling device, wherein the distilling temperature is 60-80 ℃ to obtain a distilled extract;
③ adding a humectant into the distilled extract to obtain the acne-removing essence.
The honeysuckle has the functions and efficacies, is known as a good medicine for clearing away heat and toxic materials by traditional Chinese medicine from ancient times, can be used as a medicine for stems, leaves and flowers of the honeysuckle, and has the functions of detoxifying, diminishing inflammation, killing viruses, sterilizing, promoting urination and relieving itching. The specific effects and effects of honeysuckle are as follows: 1. resisting pathogenic microorganism. Has certain inhibiting effect on various pathogenic bacteria such as staphylococcus aureus, hemolytic streptococcus, escherichia coli, dysentery bacillus, vibrio cholerae, typhoid bacillus, paratyphoid bacillus and the like; 2. has anti-inflammatory and toxic materials removing effects, and has strong effects in dispelling carbuncle, relieving swelling, clearing away heat and toxic materials, and relieving inflammation; 3. has effects in dispelling pathogenic heat, and can be used for treating affection of exogenous wind-heat or early stage of epidemic febrile disease, fever, headache, vexation, insomnia, coma, crimson tongue, dry throat and mouth; 4. has effects in cooling blood and relieving dysentery, and can be used for treating dysentery due to toxic heat, purulent blood dysentery, throat swelling and pain due to damp-warm disease, etc.; 5. the honeysuckle tea has sweet taste and cold nature, and has the functions of clearing away heat and toxic materials and dispelling wind and heat. The honeysuckle has the functions of clearing away heat and toxic materials, soothing throat, relieving summer heat and relieving restlessness. Can be used for treating summer heat, dysentery, influenza, skin ulcer, furuncle, toxic swelling, acute tonsillitis, chronic tonsillitis, and periodontitis.
Gentiana scabra Bunge can purge excessive fire in liver and gallbladder and remove damp-heat in lower-jiao. Treating excessive heat in liver channel, fright epilepsy, mania, encephalitis B, headache, conjunctival congestion, pharyngalgia, jaundice, dysentery, carbuncle, swelling, sore and ulcer, swelling and pain of scrotum, and pudendal pruritus. Can be used for treating damp-heat type cellulitis, pudendal swelling, pudendal pruritus, leukorrhagia, eczema, pruritus, deafness, hypochondriac pain, bitter taste of mouth, and convulsion. The gentian decoction has different degrees of inhibition effects on various pathogenic bacteria. The oral administration or intraperitoneal injection of the gentiline and the Longdan liquid has obvious anti-inflammatory effect, and is 4-7 times stronger than that of sodium salicylate. The gentian injection can obviously promote the phagocytic function of inflammatory cells.
The herba Menthae has effects of dispelling pathogenic wind and heat, refreshing mind, relieving sore throat, promoting eruption, dispersing stagnated liver qi, and activating qi-flowing. Mint is used not only for wind-heat exterior syndrome and warm defense system syndrome, but also for wind-cold exterior syndrome. The mint can soothe liver and regulate qi, and treat liver depression and qi stagnation, and has good curative effects on gastrointestinal qi stagnation and abdominal distension.
The actions and effects of moutan bark, cortex moutan, clear liver and reduce blood pressure, are indicated for liver depression and fire hyperactivity, fever at night, headache and eye dryness. ② the medicine for promoting blood circulation and removing blood stasis, and can be used for curing blood stasis amenorrhea, dysmenorrhea or blood stasis accumulation. ③ clear heat and cool blood, and wind-heat rash.
Preferably, the weight of the added water in the step (i) is 1000-2000 parts, and the water is deionized water, purified water or distilled water.
As the optimal proportion, the following medicinal materials in parts by weight are soaked in water in the step I:
Figure BDA0002682776460000031
preferably, the soaking time in the step (i) is 30-60 minutes.
Preferably, the distillation device in the step (II) is a distillation boiler steam generator made of a purple copper material.
Preferably, the distillation time in the step II is 30-60 minutes.
Preferably, the humectant in the step (c) is at least one of butylene glycol, glycerin, polyhydric alcohol or propylene glycol.
Preferably, the moisture-keeping agent is added in the step (c) in an amount of 0.5-1.5% by weight based on the weight of the distilled extract.
Compared with the prior art, the invention has the advantages that: honeysuckle is used as a monarch, gentian is used as a minister, mint and tree peony bark are used as an assistant and guide, and the honeysuckle has the effects of clearing away heat and toxic materials, resisting allergy, removing acne and toxin and dispelling eczema. The gentian has the effects of resisting bacteria and diminishing inflammation, clearing heat and drying dampness, purging liver and gallbladder fire, dispelling wind and heat from the mint and dispelling rubella and pruritus, and the moutan bark has the effects of activating blood and cooling blood. The low-temperature distillation can be adopted to furthest keep the effective components from being damaged on the basis of extracting the effective components as far as possible, and the utilization rate and the curative effect of the medicinal materials are taken into consideration. The invention has good curative effect on eczema, acne, furunculosis, skin inflammation, allergy, cosmetic allergy and the like caused by accumulation of skin lipotoxin and rising of liver fire. The distillation extraction is adopted, so that the purity is high, no pollution is caused, no additive is added, the drug effect is favorably exerted, and no side effect is caused.
Detailed Description
The present invention will be described in further detail with reference to examples.
Example 1 is a preferred example, and specifically, the preparation method of the acne-removing essence comprises the following steps:
soaking the medicinal materials, namely soaking the medicinal materials which are prepared from the following components in parts by weight in water for 40 minutes:
Figure BDA0002682776460000032
distilling the substances by using a distillation pot steam generator made of red copper, wherein the distillation temperature is 60-80 ℃, and the distillation time is 30-60 minutes to obtain a distillation extract;
③ adding butanediol into the distillation extract as a humectant to obtain the acne-removing essence.
The weight of the added water in the step (i) in this example is 1500 parts, and the water is distilled water. The honeysuckle is preferably wild honeysuckle, and has strong efficacy. The addition amount of butanediol is 5 parts.
The acne removing essence in the embodiment 1 is detected, and the detection result is as follows:
the appearance is uniform transparent liquid without impurities; the fragrance accords with the specified odor type; cold resistance: keeping the temperature at 5 ℃ for 24 hours, and no apparent qualitative difference exists after the temperature is restored to room temperature; heat resistance: keeping the temperature at 40 ℃ for 24 hours, and having no obvious character difference after the temperature is restored to room temperature and before the test; the pH was 5.3; the relative density was 1.0006.
Example 2, the weight ratio of the medicinal materials is as follows:
Figure BDA0002682776460000041
other conditions refer to example 1.
Example 3, the weight ratio of the medicinal materials is as follows:
Figure BDA0002682776460000042
other conditions refer to example 1.
Example 4, the weight ratio of the medicinal materials is as follows:
Figure BDA0002682776460000043
other conditions refer to example 1.
Case 1:
certain Tang, a woman, 42 years old, people in the city of Typha in Weinan, Shanxi province, years of allergic severe hormone face, skin care products and miraculous water of various brands are used, the allergic hormone face is more severe, the traditional Chinese medicines are drunk countless, a Xijing hospital deals with an affiliated skin hospital for many times, various allergic medicines prescribed by doctors can not be drunk, the traditional Chinese medicines and western medicines have no effect, the paste can not be itchy when the paste is not itchy, and the paste can not be itchy when the paste is applied.
The acne removing essence in the embodiment 1 is sprayed on the face to be fresh and cool at the beginning, five or six times are sprayed each day, water is added for drinking twice each day, a wet film is made at night, and a little effect can be felt after five or six times, firstly, itching is not generated, the face is completely cured basically when twenty or more days are insisted on using the acne removing essence, and the hormone face for many years is cured.
Case 2:
when acne removing essence in example 1 is used for one week, the acne removing essence sinks a little, is sprayed for four times every day, is insisting on compressing facial mask for wet compress for three days, is sprayed for one week, has no blackhead on the nose, grows out and is smooth, and then the acne on the two cheeks of the last week has no newly added acne. The acne on the face disappears after one month, and the face is cleaned in the morning and at night every day and then is sprayed, patted and absorbed, about seven times a day.
Case 3:
a Wang Yi, a man in 35 years old, a white sheep village-laying person in the town of the Shuoyang county of Shaoyang, Hunan province, all the cosmetic ointments about acne removal are tried, but no obvious effect is achieved, the acne removal face is full of acne removal face in the worst case, mood limitation is very vexing, the skin is worse and worse, blackheads, acnes and acne marks are repeated for more than ten years. The acne removing essence in example 1 is applied by wet dressing, four times a day is sprayed, half more months are kept, the number of acne marks on the face is small, two months are kept, the skin on the face is glossy, the acne marks and acne marks are completely repaired, and the acne marks and acne marks are not grown for two years.
Case 4:
some of the yao, a woman, 41 years old, in the city of futeng, wei nan, shaxi, started on the face from 28 years old. The ointment is better when the ointment is applied at the beginning but cannot be removed at all, the ointment is not used after the application, the application of the ointment is not effective, and the face is changed into a hormone face. Since the acne removing essence in the embodiment 1 is used, until the allergy conditions such as redness and swelling and peeling of the face do not exist for more than one year, the acne removing pure dew compressed mask is continuously prepared every morning, the acne removing pure dew compressed mask is sprayed for five or six times a day, the acne face is continuously used for more than one month, the acne face is not red and swollen, the acne removing cream is continuously used for one month, the allergy is completely cured, and the allergy phenomenon does not exist in the face of one year.
Case 5:
a certain person, male, 26 years old, Shanxi province Weinan white water county, has pockmarks growing from 12 years old, the hospital has gone through, the ointment has been wiped off, the Chinese medicine has drunk, no effect, the patient has seen twice in the Xian Xijing hospital at 18 years old, the internal regulation and external application of the medicine are opened in two bags, but the treatment is not the primary cause, the application is not long, and the treatment is started after a period of time. Since the acne removing essence in the embodiment 1 is used for half a month, acne on the forehead is flat, the face is touched seven or eight times a day, the face is worn in a bag at work and can be sprayed anytime and anywhere, the taste is good, the mask is compressed once every other day, the face keeps glossy for two months, the blackheads are much less, and the closed acne is less once.

Claims (8)

1. The preparation method of the acne-removing essence is characterized by comprising the following steps:
soaking the medicinal materials, namely soaking the medicinal materials which comprise the following components in parts by weight in water:
Figure FDA0002682776450000011
distilling the substances by using a distilling device, wherein the distilling temperature is 60-80 ℃ to obtain a distilled extract;
③ adding a humectant into the distilled extract to obtain the acne-removing essence.
2. The preparation method of the acne-removing essence according to claim 1, characterized in that the water in the step (i) is added in an amount of 1000-2000 parts by weight, and the water is deionized water, purified water or distilled water.
3. The preparation method of the acne-removing essence according to claim 1, which is characterized in that the following medicinal materials in parts by weight are soaked in water in the step (i):
Figure FDA0002682776450000012
4. the preparation method of the acne-removing essence according to claim 1, characterized in that the soaking time in the step (i) is 30-60 minutes.
5. The preparation method of the acne-removing essence according to claim 1, wherein the distillation device in the step (II) is a distillation boiler steam generator made of a purple copper material.
6. The preparation method of the acne-removing essence according to claim 1, wherein the distillation time in the step (II) is 30-60 minutes.
7. The preparation method of the essence for removing acne according to claim 1, characterized in that the moisturizing agent in step (iii) is at least one of butylene glycol, glycerin, polyhydric alcohol or propylene glycol.
8. The preparation method of the acne-removing essence according to claim 5, wherein the moisture-retaining agent is added in an amount of 0.5-1.5% by weight of the distilled extract.
CN202010967177.4A 2020-09-15 2020-09-15 Preparation method of acne-removing essence Pending CN111991296A (en)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104510880A (en) * 2013-09-27 2015-04-15 青岛畅绿生物研究所 Lotus acne-eliminating essence lotion
CN105727110A (en) * 2016-04-13 2016-07-06 冯小林 Traditional Chinese medicine washing liquid for treating gynecological inflammation and preparing method thereof
CN106256344A (en) * 2016-08-30 2016-12-28 郭清辉 A kind of Flos Lonicerae quintessence oil dew and preparation method thereof
CN107412067A (en) * 2017-08-22 2017-12-01 安徽省中日农业环保科技有限公司 A kind of preparation method of the anti-acne essence containing Honegsukle flower P.E
CN107913209A (en) * 2016-10-10 2018-04-17 申扬阳 Anti-inflammation plant toner
CN110179704A (en) * 2019-05-09 2019-08-30 广州颜尚化妆品有限公司 A kind of Honegsukle flower P.E and its preparation method and application

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104510880A (en) * 2013-09-27 2015-04-15 青岛畅绿生物研究所 Lotus acne-eliminating essence lotion
CN105727110A (en) * 2016-04-13 2016-07-06 冯小林 Traditional Chinese medicine washing liquid for treating gynecological inflammation and preparing method thereof
CN106256344A (en) * 2016-08-30 2016-12-28 郭清辉 A kind of Flos Lonicerae quintessence oil dew and preparation method thereof
CN107913209A (en) * 2016-10-10 2018-04-17 申扬阳 Anti-inflammation plant toner
CN107412067A (en) * 2017-08-22 2017-12-01 安徽省中日农业环保科技有限公司 A kind of preparation method of the anti-acne essence containing Honegsukle flower P.E
CN110179704A (en) * 2019-05-09 2019-08-30 广州颜尚化妆品有限公司 A kind of Honegsukle flower P.E and its preparation method and application

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Application publication date: 20201127