CN111991142A - Medical eye-shade - Google Patents

Medical eye-shade Download PDF

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Publication number
CN111991142A
CN111991142A CN202010925098.7A CN202010925098A CN111991142A CN 111991142 A CN111991142 A CN 111991142A CN 202010925098 A CN202010925098 A CN 202010925098A CN 111991142 A CN111991142 A CN 111991142A
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Prior art keywords
chitosan
parts
inner liner
eye
base layer
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Withdrawn
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CN202010925098.7A
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Chinese (zh)
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魏长同
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Individual
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Individual
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/04Eye-masks ; Devices to be worn on the face, not intended for looking through; Eye-pads for sunbathing
    • A61F9/045Eye-shades or visors; Shields beside, between or below the eyes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/12Bandages or dressings; Absorbent pads specially adapted for the head or neck
    • A61F13/122Bandages or dressings; Absorbent pads specially adapted for the head or neck specially adapted for the face
    • A61F13/124Bandages or dressings; Absorbent pads specially adapted for the head or neck specially adapted for the face specially adapted for the eyes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/722Chitin, chitosan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/24Mucus; Mucous glands; Bursa; Synovial fluid; Arthral fluid; Excreta; Spinal fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Zoology (AREA)
  • Insects & Arthropods (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Vascular Medicine (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Animal Husbandry (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Hematology (AREA)

Abstract

The invention discloses a medical eye patch, which comprises an eye patch body and a binding piece arranged on the eye patch body, wherein the eye patch body comprises a base layer and an inner liner layer, a temperature-regulating phase-change microcapsule is filled in the base layer, the inner liner layer is chitosan-collagen composite sponge, and the chitosan-collagen composite sponge contains a traditional Chinese medicine decoction. The base layer can keep the temperature of eyes and surrounding tissues to be the optimum temperature of a human body, and is favorable for quick recovery of the eyes. The inner liner has good water absorption, biocompatibility and air permeability, is easy to attach to skin and cannot be adhered to a wound, has the effects of improving eyesight, stopping bleeding, resisting inflammation, sterilizing, reducing scars and repairing tissues after the traditional Chinese medicine components are added, and has good application prospect.

Description

Medical eye-shade
Technical Field
The invention belongs to the technical field of medicines, and particularly relates to a medical eyeshade.
Technical Field
The eye mask is used for protecting wounds after ophthalmic surgery. The existing eyeshade includes an eyeshade body and a binding member for fixing the eyeshade body on a head, and the eyeshade body includes a base layer and an inner liner layer disposed on an inner surface of the base layer. The existing eyeshade has no temperature regulation function on tissues around a wound, the growth of bacteria is facilitated due to too high temperature, and in addition, the body can sweat due to the high temperature, so that infection is easily caused, and the healing of the wound is not facilitated; if the temperature is too low, the growth and metabolism of human tissues can be slowed down, and the recovery of wounds is not facilitated. The current eye-shade body inner liner is mostly medical gauze, and the gauze is easy and the wound adhesion, and gauze and eye laminating degree are lower, in order to stanch, anti-inflammatory and bactericidal the wound, need set up the one deck medicine on wound or gauze, and the medicine easily slips off. In addition, most of the existing eyepatches are binocular eyepatches, but most of ophthalmic operations only involve one eye, which not only causes unnecessary resource waste, but also brings inconvenience to life of patients and medication of doctors.
Disclosure of Invention
In order to solve the defects of the prior art, the invention provides a medical eyeshade.
The technical scheme adopted by the invention is as follows: the utility model provides a medical eye patch, includes eye patch body and the binding piece of setting on eye patch body, eye patch body includes basic unit and inner liner, the basic unit includes the two-layer plastic film that overlaps, and the two-layer plastic film that overlaps adopts heat-seal process to process into the net check, and every net check intussuseption is filled with the phase transition microcapsule of adjusting temperature, the inner liner sets up on the basic unit internal surface, and the inner liner includes chitosan-collagen composite sponge, contains the following traditional chinese medicine decoction in the chitosan-collagen composite sponge: 8-12 parts of bat dung, 4-8 parts of cicada slough, 6-10 parts of aralia elata seem and 3-5 parts of lavender, wherein the binding piece comprises through holes arranged on the left side and the right side of the base layer, the through holes on the left side and the right side can be mutually buckled, and elastic bands are arranged on the through holes on the left side and the right side.
The preparation method of the inner liner layer of the eye mask body comprises the following steps:
(1) dissolving a certain amount of chitosan in a certain amount of 0.2M acetic acid solution to obtain a 5% chitosan solution,
(2) dissolving a certain amount of collagen in a certain amount of deionized water to obtain a 3% collagen solution,
(3) the two solutions prepared in the step (1) and the step (2) are evenly mixed according to the proportion of 1: 1,
(4) pouring the mixed solution prepared in the step (3) into a mould, freezing at the temperature of minus 20 ℃, freeze-drying for two days, taking out the freeze-dried sample from the mould,
(5) soaking the freeze-dried sample prepared in the step (4) in methanol for 3-5 h, pouring out the methanol, freeze-drying for two days to remove the methanol to obtain the chitosan-collagen composite sponge,
(6) mixing 8-12 parts by weight of bat dung, 4-8 parts by weight of cicada slough, 6-10 parts by weight of cephalanoplos segetum and 3-5 parts by weight of lavender, adding water to immerse the materials, heating and decocting for 1-2 h, filtering to obtain a traditional Chinese medicine decoction,
(7) and (3) soaking the chitosan-collagen composite sponge prepared in the step (5) in the decoction of the traditional Chinese medicine prepared in the step (6) for 3-6 hours, taking out, draining, and partially dehydrating to finally prepare the inner liner of the eye mask body.
When the eye patch is used, if the eye patch is used for treating single eye diseases, a single eye patch body is selected, the elastic band is used for fixing the single eye patch body through the perforation holes on the left side and the right side of the base layer, if the eye patch is used for treating double eye diseases, two eye patch bodies are selected and buckled together through the perforation holes on the base layer, and the elastic band is used for fixing the two eye patch bodies through the perforation holes on the base layer.
The study shows that the optimum temperature of the human body is 18-24 ℃, and the eye healing is also best at the temperature. The high temperature is favorable for the growth of bacteria, and in addition, the high temperature can cause the body to sweat, easily cause infection and is not favorable for the healing of wounds; if the temperature is too low, the growth and metabolism of human tissues can be slowed down, and the recovery of wounds is not facilitated. It is therefore desirable that the eye wound heal quickly, and it is best to keep the eye and surrounding tissues at an appropriate temperature. The base layer is provided with the temperature-regulating phase-change microcapsules, so that the temperature of eyes and surrounding tissues can be kept at the optimum temperature of a human body, and the rapid recovery of the eyes is facilitated.
The chitosan is a natural polymer material, has good antibacterial property, biocompatibility and biodegradability, strengthens the immunologic function of a human body, and can eliminate harmful substances in the body.
The collagen can supplement skin nutrition, promote cell activity, help and promote skin to heal rapidly; the elasticity of collagen skin bonds and elastic nets supporting the skin is maintained, the spiral net structure of cells is protected from being damaged, and skin tissues are prevented from shrinking and collapsing to scar; in addition, collagen reacts with platelets to cause a series of processes associated with blood aggregation to proceed, thereby rapidly stopping bleeding.
The inner lining layer chitosan-collagen composite sponge has a porous structure and good water absorption, can continuously absorb the exudates of eyes or wounds, keeps the eyes and surrounding tissues dry for a long time and promotes the wound healing; the chitosan-collagen composite sponge has good biocompatibility and air permeability, is easy to be attached to skin and cannot be adhered to wounds.
The faeces Vespertilionis has effects of removing liver fire, improving eyesight, removing blood stasis, and resolving food stagnation, and can be used for treating conjunctival congestion, swelling and pain, leucorrhea with blood, nebula, lymphoid tuberculosis, and malaria; periostracum Cicadae has effects of dispelling pathogenic wind, clearing heat away, arresting convulsion, relieving spasm, improving eyesight, and removing nebula; (ii) a The Chinese thorowax root has the effects of cooling blood, stopping bleeding, removing blood stasis, relieving swelling and resisting bacteria, and is used for treating traumatic bleeding, carbuncle, swelling and sore; lavender has antiinflammatory, antibacterial, antioxidant, spasmolytic, tranquilizing, neuroprotective and other pharmacological activities, and has the effects of promoting cell regeneration, accelerating wound healing, inhibiting bacteria, reducing scar, resisting virus, killing bacteria, relieving pain, resisting inflammation, repairing wound surface tissue, shortening healing time, and reducing scar tissue hyperplasia.
After the traditional Chinese medicine components are added into the chitosan-collagen composite sponge, the chitosan-collagen composite sponge has the effects of improving eyesight, stopping bleeding, resisting inflammation, sterilizing, reducing scars and repairing tissues, has no toxic or side effect, and has good application prospect.
Drawings
Fig. 1 is a schematic structural diagram of the present invention.
Fig. 2 is a schematic structural view of the present invention for treating diseases of both eyes.
Detailed Description
The invention is further described below with reference to the accompanying drawings.
The utility model provides a medical eye patch, includes eye patch body 1 and the binding 2 of setting on eye patch body 1, eye patch body 1 includes basic unit 3 and inner liner 4, basic unit 3 includes the two-layer membrane of moulding that overlaps, and the two-layer membrane of moulding that overlaps adopts heat-seal process to process into network check 5, and every 5 intussuseption of network check are filled with phase transition microcapsules 6 that adjust the temperature, inner liner 4 sets up on 3 internal surfaces of basic unit, and inner liner 4 includes chitosan-collagen composite sponge, contains in the chitosan-collagen composite sponge following traditional chinese medicine decoction: 8-12 parts of bat dung, 4-8 parts of cicada slough, 6-10 parts of aralia elata seem and 3-5 parts of lavender, wherein the binding piece 2 comprises through holes 7 arranged on the left side and the right side of the base layer 3, the through holes 7 on the left side and the right side can be mutually buckled, and elastic bands 8 are arranged on the through holes 7 on the left side and the right side.
The preparation method of the inner liner layer 4 of the eye mask body 1 comprises the following steps:
(1) dissolving a certain amount of chitosan in a certain amount of 0.2M acetic acid solution to obtain a 5% chitosan solution,
(2) dissolving a certain amount of collagen in a certain amount of deionized water to obtain a 3% collagen solution,
(3) the two solutions prepared in the step (1) and the step (2) are evenly mixed according to the proportion of 1: 1,
(4) pouring the mixed solution prepared in the step (3) into a mould, freezing at the temperature of minus 20 ℃, freeze-drying for two days, taking out the freeze-dried sample from the mould,
(5) soaking the freeze-dried sample prepared in the step (4) in methanol for 3-5 h, pouring out the methanol, freeze-drying for two days to remove the methanol to obtain the chitosan-collagen composite sponge,
(6) mixing 8-12 parts by weight of bat dung, 4-8 parts by weight of cicada slough, 6-10 parts by weight of cephalanoplos segetum and 3-5 parts by weight of lavender, adding water to immerse the materials, heating and decocting for 1-2 h, filtering to obtain a traditional Chinese medicine decoction,
(7) and (3) soaking the chitosan-collagen composite sponge prepared in the step (5) in the decoction of the traditional Chinese medicine prepared in the step (6) for 3-6 hours, taking out, draining, and partially dehydrating to finally prepare the inner liner of the eye mask body.

Claims (2)

1. The utility model provides a medical eye-shade, includes eye-shade body and the binding of setting on eye-shade body, characterized by: the eye patch body comprises a base layer and an inner liner, wherein the base layer comprises two layers of overlapped plastic films, the two layers of overlapped plastic films are processed into network lattices by adopting a heat sealing process, each network lattice is filled with a temperature-adjusting phase-change microcapsule, the inner liner is arranged on the inner surface of the base layer, the inner liner comprises chitosan-collagen composite sponge, and the chitosan-collagen composite sponge contains the following traditional Chinese medicine decoction: 8-12 parts of bat dung, 4-8 parts of cicada slough, 6-10 parts of aralia elata seem and 3-5 parts of lavender, wherein the binding piece comprises through holes arranged on the left side and the right side of the base layer, the through holes on the left side and the right side can be mutually buckled, and elastic bands are arranged on the through holes on the left side and the right side.
2. The medical eye shield of claim 1, wherein: the preparation method of the inner liner layer of the eye mask body comprises the following steps,
(1) dissolving a certain amount of chitosan in a certain amount of 0.2M acetic acid solution to obtain a 5% chitosan solution,
(2) dissolving a certain amount of collagen in a certain amount of deionized water to obtain a 3% collagen solution,
(3) the two solutions prepared in the step (1) and the step (2) are evenly mixed according to the proportion of 1: 1,
(4) pouring the mixed solution prepared in the step (3) into a mould, freezing at the temperature of minus 20 ℃, freeze-drying for two days, taking out the freeze-dried sample from the mould,
(5) soaking the freeze-dried sample prepared in the step (4) in methanol for 3-5 h, pouring out the methanol, freeze-drying for two days to remove the methanol to obtain the chitosan-collagen composite sponge,
(6) mixing 8-12 parts by weight of bat dung, 4-8 parts by weight of cicada slough, 6-10 parts by weight of cephalanoplos segetum and 3-5 parts by weight of lavender, adding water to immerse the materials, heating and decocting for 1-2 h, filtering to obtain a traditional Chinese medicine decoction,
(7) and (3) soaking the chitosan-collagen composite sponge prepared in the step (5) in the decoction of the traditional Chinese medicine prepared in the step (6) for 3-6 hours, taking out, draining, and partially dehydrating to finally prepare the inner liner of the eye mask body.
CN202010925098.7A 2020-09-06 2020-09-06 Medical eye-shade Withdrawn CN111991142A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010925098.7A CN111991142A (en) 2020-09-06 2020-09-06 Medical eye-shade

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010925098.7A CN111991142A (en) 2020-09-06 2020-09-06 Medical eye-shade

Publications (1)

Publication Number Publication Date
CN111991142A true CN111991142A (en) 2020-11-27

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202010925098.7A Withdrawn CN111991142A (en) 2020-09-06 2020-09-06 Medical eye-shade

Country Status (1)

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CN (1) CN111991142A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113616419A (en) * 2021-09-10 2021-11-09 天津富勤科技股份有限公司 Steam eye-shade

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113616419A (en) * 2021-09-10 2021-11-09 天津富勤科技股份有限公司 Steam eye-shade

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