CN111971033A - 包含有机硅丙烯酸杂化聚合物的透皮治疗系统 - Google Patents

包含有机硅丙烯酸杂化聚合物的透皮治疗系统 Download PDF

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Publication number
CN111971033A
CN111971033A CN201980025658.9A CN201980025658A CN111971033A CN 111971033 A CN111971033 A CN 111971033A CN 201980025658 A CN201980025658 A CN 201980025658A CN 111971033 A CN111971033 A CN 111971033A
Authority
CN
China
Prior art keywords
active agent
silicone
transdermal therapeutic
therapeutic system
layer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201980025658.9A
Other languages
English (en)
Chinese (zh)
Inventor
M.埃姆根布罗伊赫
G.沃尔
M.林
R.勃姆
C.施密茨
R.考夫曼
H-W.沃尔夫
N.鲁姆
A.施吕特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
LTS Lohmann Therapie Systeme AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LTS Lohmann Therapie Systeme AG filed Critical LTS Lohmann Therapie Systeme AG
Publication of CN111971033A publication Critical patent/CN111971033A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

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  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201980025658.9A 2018-03-13 2019-03-11 包含有机硅丙烯酸杂化聚合物的透皮治疗系统 Pending CN111971033A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18161436.3 2018-03-13
EP18161436 2018-03-13
PCT/EP2019/056025 WO2019175106A1 (en) 2018-03-13 2019-03-11 Transdermal therapeutic system comprising a silicone acrylic hybrid polymer

Publications (1)

Publication Number Publication Date
CN111971033A true CN111971033A (zh) 2020-11-20

Family

ID=61628188

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201980025658.9A Pending CN111971033A (zh) 2018-03-13 2019-03-11 包含有机硅丙烯酸杂化聚合物的透皮治疗系统

Country Status (7)

Country Link
US (1) US20210008000A1 (https=)
EP (1) EP3764997A1 (https=)
JP (1) JP2021515791A (https=)
CN (1) CN111971033A (https=)
BR (1) BR112020018290A2 (https=)
CA (1) CA3092752A1 (https=)
WO (1) WO2019175106A1 (https=)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103130966A (zh) * 2011-11-29 2013-06-05 道康宁公司 硅氧烷丙烯酸酯杂合组合物及其制备方法
CN105007906A (zh) * 2012-12-12 2015-10-28 Lts勒曼治疗系统股份公司 经皮递送系统
WO2016130408A1 (en) * 2015-02-09 2016-08-18 Dow Corning Corporation Multi-phase silicone acrylic hybrid visco-elastic compositions and methods of making same
WO2018015424A1 (en) * 2016-07-22 2018-01-25 Lts Lohmann Therapie-Systeme Ag Control of adhesive domains

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5362496A (en) * 1993-08-04 1994-11-08 Pharmetrix Corporation Method and therapeutic system for smoking cessation
US6974588B1 (en) * 1999-12-07 2005-12-13 Elan Pharma International Limited Transdermal patch for delivering volatile liquid drugs
TWI389709B (zh) * 2005-12-01 2013-03-21 Novartis Ag 經皮治療系統
EP2024406B1 (en) 2006-06-06 2012-08-01 Dow Corning Corporation A silicone acrylate hybrid composition
BRPI1014886B1 (pt) 2009-04-24 2020-02-11 Henkel IP & Holding GmbH Polímeros acrílicos de silicone híbridos, seus métodos de preparação, adesivos e soluções de uma composição adesiva sensível à pressão compreendendo os mesmos.
TW201338813A (zh) 2011-12-12 2013-10-01 洛曼治療系統股份有限公司 經皮遞送系統
US20170112781A1 (en) * 2015-10-27 2017-04-27 Noven Pharmaceuticals, Inc. Transdermal drug delivery systems with polyisobutylene face adhesive

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103130966A (zh) * 2011-11-29 2013-06-05 道康宁公司 硅氧烷丙烯酸酯杂合组合物及其制备方法
CN105007906A (zh) * 2012-12-12 2015-10-28 Lts勒曼治疗系统股份公司 经皮递送系统
WO2016130408A1 (en) * 2015-02-09 2016-08-18 Dow Corning Corporation Multi-phase silicone acrylic hybrid visco-elastic compositions and methods of making same
WO2018015424A1 (en) * 2016-07-22 2018-01-25 Lts Lohmann Therapie-Systeme Ag Control of adhesive domains

Also Published As

Publication number Publication date
US20210008000A1 (en) 2021-01-14
CA3092752A1 (en) 2019-09-19
EP3764997A1 (en) 2021-01-20
JP2021515791A (ja) 2021-06-24
BR112020018290A2 (pt) 2020-12-29
WO2019175106A1 (en) 2019-09-19

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Application publication date: 20201120