CN111886016A - 治疗脊髓损伤的组合物和方法 - Google Patents

治疗脊髓损伤的组合物和方法 Download PDF

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CN111886016A
CN111886016A CN201980020725.8A CN201980020725A CN111886016A CN 111886016 A CN111886016 A CN 111886016A CN 201980020725 A CN201980020725 A CN 201980020725A CN 111886016 A CN111886016 A CN 111886016A
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cells
neural
e4orf1
composition
subject
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CN201980020725.8A
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English (en)
Chinese (zh)
Inventor
D·J·诺兰
M·A·莱恩
L·强
L·V·若卢杰夫瓦
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Drexel University
Angiocrine Bioscience Inc
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Drexel University
Angiocrine Bioscience Inc
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    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
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    • A61L27/3878—Nerve tissue, brain, spinal cord, nerves, dura mater
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CN201980020725.8A 2018-01-22 2019-01-22 治疗脊髓损伤的组合物和方法 Pending CN111886016A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862620269P 2018-01-22 2018-01-22
US62/620,269 2018-01-22
PCT/US2019/014497 WO2019144102A1 (en) 2018-01-22 2019-01-22 Compositions and methods for treatment of spinal cord injury

Publications (1)

Publication Number Publication Date
CN111886016A true CN111886016A (zh) 2020-11-03

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US (1) US20210030810A1 (https=)
EP (1) EP3743085A4 (https=)
JP (1) JP7391308B2 (https=)
CN (1) CN111886016A (https=)
AU (1) AU2019209439A1 (https=)
CA (1) CA3089324A1 (https=)
WO (1) WO2019144102A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3512937B1 (en) 2016-09-13 2024-10-09 Angiocrine Bioscience, Inc. Blood-brain barrier comprising engineered endothelial cells

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140045260A1 (en) * 2007-01-19 2014-02-13 Cornell Research Foundation, Inc. Methods and compositions for promoting survival and proliferation of endothelial cells and stimulating angiogenesis
WO2015200897A2 (en) * 2014-06-27 2015-12-30 Angiocrine Bioscience, Inc. Neural cells expressing adenovirus e4orf1, and methods of making and using the same
WO2016209057A2 (ko) * 2015-06-26 2016-12-29 연세대학교 산학협력단 신경전구세포의 분비단백체를 유효성분으로 포함하는 허혈성 질환 또는 신경염증 질환 치료용 조성물
WO2017015246A1 (en) * 2015-07-20 2017-01-26 Angiocrine Bioscience, Inc. Engineered endothelial cells expressing an ets transcription factor
US20170136068A1 (en) * 2014-06-27 2017-05-18 Industry-Academic Cooperation Foundation, Yonsei University Composition for treating ischemic diseases or neuroinflammatory diseases containing neural progenitor cells or secretome thereof as active ingredient

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140045260A1 (en) * 2007-01-19 2014-02-13 Cornell Research Foundation, Inc. Methods and compositions for promoting survival and proliferation of endothelial cells and stimulating angiogenesis
US20180258386A1 (en) * 2007-01-19 2018-09-13 Cornell Research Foundation, Inc. Methods and compositions for promoting survival and proliferation of endothelial cells and stimulating angiogensis
WO2015200897A2 (en) * 2014-06-27 2015-12-30 Angiocrine Bioscience, Inc. Neural cells expressing adenovirus e4orf1, and methods of making and using the same
CN106574243A (zh) * 2014-06-27 2017-04-19 安吉克莱茵生物科学有限公司 表达腺病毒e4orf1的神经细胞及其制备方法和应用
US20170136068A1 (en) * 2014-06-27 2017-05-18 Industry-Academic Cooperation Foundation, Yonsei University Composition for treating ischemic diseases or neuroinflammatory diseases containing neural progenitor cells or secretome thereof as active ingredient
CN106714814A (zh) * 2014-06-27 2017-05-24 S生物医药公司 包含神经前体细胞或其分泌蛋白质组作为有效成分的治疗缺血性疾病或神经炎症性疾病的组合物
WO2016209057A2 (ko) * 2015-06-26 2016-12-29 연세대학교 산학협력단 신경전구세포의 분비단백체를 유효성분으로 포함하는 허혈성 질환 또는 신경염증 질환 치료용 조성물
CN107921068A (zh) * 2015-06-26 2018-04-17 S生物医药公司 包含神经前体细胞的分泌蛋白质组作为有效成分的用于治疗缺血性疾病或神经炎症疾病的组合物
WO2017015246A1 (en) * 2015-07-20 2017-01-26 Angiocrine Bioscience, Inc. Engineered endothelial cells expressing an ets transcription factor
CN108291196A (zh) * 2015-07-20 2018-07-17 安吉克莱茵生物科学有限公司 表达ets转录因子的工程化的内皮细胞

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WO2019144102A1 (en) 2019-07-25
AU2019209439A1 (en) 2020-08-13
EP3743085A4 (en) 2021-10-20
JP7391308B2 (ja) 2023-12-05
US20210030810A1 (en) 2021-02-04
EP3743085A1 (en) 2020-12-02
JP2021512148A (ja) 2021-05-13
CA3089324A1 (en) 2019-07-25

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