JP7391308B2 - 脊髄損傷の治療のための組成物および方法 - Google Patents
脊髄損傷の治療のための組成物および方法 Download PDFInfo
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- JP7391308B2 JP7391308B2 JP2020561572A JP2020561572A JP7391308B2 JP 7391308 B2 JP7391308 B2 JP 7391308B2 JP 2020561572 A JP2020561572 A JP 2020561572A JP 2020561572 A JP2020561572 A JP 2020561572A JP 7391308 B2 JP7391308 B2 JP 7391308B2
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- A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
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- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
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- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3808—Endothelial cells
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- A—HUMAN NECESSITIES
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/383—Nerve cells, e.g. dendritic cells, Schwann cells
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3878—Nerve tissue, brain, spinal cord, nerves, dura mater
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3886—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- A—HUMAN NECESSITIES
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- C12N2740/16041—Use of virus, viral particle or viral elements as a vector
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- Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Developmental Biology & Embryology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Botany (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Ophthalmology & Optometry (AREA)
- Wood Science & Technology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Mycology (AREA)
- Orthopedic Medicine & Surgery (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862620269P | 2018-01-22 | 2018-01-22 | |
| US62/620,269 | 2018-01-22 | ||
| PCT/US2019/014497 WO2019144102A1 (en) | 2018-01-22 | 2019-01-22 | Compositions and methods for treatment of spinal cord injury |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021512148A JP2021512148A (ja) | 2021-05-13 |
| JP2021512148A5 JP2021512148A5 (https=) | 2022-02-24 |
| JPWO2019144102A5 JPWO2019144102A5 (https=) | 2022-02-24 |
| JP7391308B2 true JP7391308B2 (ja) | 2023-12-05 |
Family
ID=67301897
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020561572A Active JP7391308B2 (ja) | 2018-01-22 | 2019-01-22 | 脊髄損傷の治療のための組成物および方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20210030810A1 (https=) |
| EP (1) | EP3743085A4 (https=) |
| JP (1) | JP7391308B2 (https=) |
| CN (1) | CN111886016A (https=) |
| AU (1) | AU2019209439A1 (https=) |
| CA (1) | CA3089324A1 (https=) |
| WO (1) | WO2019144102A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3512937B1 (en) | 2016-09-13 | 2024-10-09 | Angiocrine Bioscience, Inc. | Blood-brain barrier comprising engineered endothelial cells |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017015246A1 (en) | 2015-07-20 | 2017-01-26 | Angiocrine Bioscience, Inc. | Engineered endothelial cells expressing an ets transcription factor |
| JP2017522047A (ja) | 2014-06-27 | 2017-08-10 | アンジオクライン・バイオサイエンス・インコーポレイテッドAngiocrine Bioscience, Inc. | アデノウイルスe4qrf1を発現する神経系細胞、並びに、その製造および使用方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008089448A2 (en) * | 2007-01-19 | 2008-07-24 | Cornell Presearch Foundation, Inc. | Methods and compositions for promoting survival & proliferation of endothelial cells & stimulating angiogenesis |
| KR101675123B1 (ko) * | 2014-06-27 | 2016-11-14 | 연세대학교 산학협력단 | Psa-ncam-양성 신경전구세포를 유효성분으로 포함하는 허혈성 질환 또는 신경염증 질환 치료용 조성물 |
| ES2815537T3 (es) * | 2015-06-26 | 2021-03-30 | S Biomedics | Composición para el tratamiento de enfermedades isquémicas o trastornos inflamatorios neurogénicos, que contienen el secretoma de células progenitoras neurales como ingrediente activo |
-
2019
- 2019-01-22 CN CN201980020725.8A patent/CN111886016A/zh active Pending
- 2019-01-22 US US16/963,897 patent/US20210030810A1/en not_active Abandoned
- 2019-01-22 CA CA3089324A patent/CA3089324A1/en active Pending
- 2019-01-22 JP JP2020561572A patent/JP7391308B2/ja active Active
- 2019-01-22 WO PCT/US2019/014497 patent/WO2019144102A1/en not_active Ceased
- 2019-01-22 EP EP19741215.8A patent/EP3743085A4/en not_active Withdrawn
- 2019-01-22 AU AU2019209439A patent/AU2019209439A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017522047A (ja) | 2014-06-27 | 2017-08-10 | アンジオクライン・バイオサイエンス・インコーポレイテッドAngiocrine Bioscience, Inc. | アデノウイルスe4qrf1を発現する神経系細胞、並びに、その製造および使用方法 |
| WO2017015246A1 (en) | 2015-07-20 | 2017-01-26 | Angiocrine Bioscience, Inc. | Engineered endothelial cells expressing an ets transcription factor |
Non-Patent Citations (3)
| Title |
|---|
| Ann. N.Y. Acad. Sci.,2017年,Vol.1410,pp.44-56 |
| Cell Biology International,2008年,Vol.32,pp.1546-1558 |
| JOURNAL OF NEUROTRAUMA,2011年,Vol.28,pp.1611-1682 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN111886016A (zh) | 2020-11-03 |
| WO2019144102A1 (en) | 2019-07-25 |
| AU2019209439A1 (en) | 2020-08-13 |
| EP3743085A4 (en) | 2021-10-20 |
| US20210030810A1 (en) | 2021-02-04 |
| EP3743085A1 (en) | 2020-12-02 |
| JP2021512148A (ja) | 2021-05-13 |
| CA3089324A1 (en) | 2019-07-25 |
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