CN111816044A - Simulated rabbit for experiment - Google Patents

Simulated rabbit for experiment Download PDF

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Publication number
CN111816044A
CN111816044A CN202010840955.3A CN202010840955A CN111816044A CN 111816044 A CN111816044 A CN 111816044A CN 202010840955 A CN202010840955 A CN 202010840955A CN 111816044 A CN111816044 A CN 111816044A
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China
Prior art keywords
simulated
organ
rabbit
experimental
opening
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CN202010840955.3A
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Chinese (zh)
Inventor
朱亮
吴云红
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Individual
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Individual
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    • GPHYSICS
    • G09EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
    • G09BEDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
    • G09B23/00Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
    • G09B23/28Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
    • GPHYSICS
    • G09EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
    • G09BEDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
    • G09B23/00Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
    • G09B23/36Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for zoology

Abstract

The invention relates to the field of experimental apparatus or teaching auxiliary materials, in particular to a simulated rabbit for experiments, which comprises a supporting framework and a surface tissue, wherein the surface tissue is installed and connected on the supporting framework, and a temperature control module for controlling the surface temperature of the surface tissue is arranged in the surface tissue; a simulation organ is arranged in the supporting framework, and each unit of the simulation organ is modeled with each organ of the rabbit; the surface tissue corresponding to each unit of the simulated organ is provided with an opening and closing member, the opening and closing of the opening and closing member simulates anatomical movement, one side of the simulated organ far away from the opening and closing member is provided with a detection module, and the detection module is used for monitoring the state of the simulated organ and generating signals outwards. The invention has the beneficial effects that: the experimental animals required by the experiment are reduced or replaced, the 3R basic principle of welfare of the experimental animals is met, and the implementation of various experimental teaching is facilitated.

Description

Simulated rabbit for experiment
Technical Field
The invention relates to the field of experimental instruments or teaching auxiliary materials, in particular to an experimental simulated rabbit.
Background
In recent years, the national places more importance on experimental teaching of medical colleges, experimental animals serve as subject research objects in the teaching process and play more and more important basic supporting role, and according to the welfare criteria of the experimental animals, all colleges and universities developing animal experiments should follow the 3R (Reduction, Replacement, optimization) principle.
However, in the experimental teaching process, in order to make students more intuitively learn important knowledge points in the disciplines of physiology, pathophysiology, pharmacology, pathogenic biology and the like and record the physiological index changes of the students under various intervention conditions, the use of experimental animals cannot be avoided, such as: the experimental teaching of rabbits, toads, mice, rats, guinea pigs, dogs and the like still needs to use a large amount of experimental animals every year, the animals need to be killed after an acute experiment, even the death of the animals may occur in the experimental process due to accidents such as anesthesia and the like, and the experimental teaching does not conform to the 3R basic principle of the welfare of the experimental animals.
Disclosure of Invention
The invention aims to provide an experimental simulated rabbit to solve the problems in the background technology.
In order to achieve the purpose, the invention provides the following technical scheme:
a simulated rabbit for experiments comprises a supporting framework and surface tissues which are arranged and connected on the supporting framework, wherein a temperature control module for controlling the surface temperature of the surface tissues is arranged in the surface tissues; a simulation organ is arranged in the supporting framework, and each unit of the simulation organ is modeled with each organ of the rabbit; the surface tissue corresponding to each unit of the simulated organ is provided with an opening and closing member, the opening and closing of the opening and closing member simulates anatomical movement, one side of the simulated organ far away from the opening and closing member is provided with a detection module, and the detection module is used for monitoring the state of the simulated organ and generating signals outwards.
As a further scheme of the invention: each joint of the support framework is movably connected through a connecting piece.
As a still further scheme of the invention: the simulated organ comprises at least: liver, kidney, bladder, heart and two lungs, and set up as: the liver is a source of venous pressure and is connected with a venous blood vessel; the kidney is the source of arterial pressure and is connected with an arterial blood vessel; the bladder is connected with a ureter; the heart comprises a right atrium, a right ventricle, a left atrium and a left ventricle which are composed of four cavities filled with pigments with different colors.
As a still further scheme of the invention: the manufacturing material of each unit of the simulated organ is one of the following materials: silica gel, silica gel and gel mixed material.
As a still further scheme of the invention: and liquid with different colors is injected into the cavity of each unit of the simulation organ.
As a still further scheme of the invention: the artificial organ further comprises a rabbit ear, a balloon is detachably mounted at the ear root of the rabbit ear, and the balloon is connected with the vein on the ear edge of the rabbit ear.
As a still further scheme of the invention: be equipped with neck unit in the surface tissue, it includes trachea, common carotid artery and common jugular vein, the trachea is connected two lungs, common carotid artery and common jugular vein connect the left ventricle and the right atrium that the heart was equipped with respectively.
As a still further scheme of the invention: the lateral part of the common carotid artery is provided with a nerve, the nerve comprises a plurality of elastic parts with different diameters, and two ends of each elastic part are hung on hanging rings arranged on the surface tissue respectively.
As a still further scheme of the invention: the detection module comprises a power supply and an electronic baroreceptor, and the electronic baroreceptor is arranged on one side of the simulated organ, which is far away from the combined piece, and is used for monitoring the state of the simulated organ and generating a signal outwards; the power supply provides electrical energy.
As a still further scheme of the invention: the device further comprises a positioner arranged in the supporting framework, and the positioner sends a position signal outwards.
Compared with the prior art, the invention has the beneficial effects that: the experimental simulated rabbit is used for experiments, reduces or replaces experimental animals required by teaching experiments, accords with the 3R basic principle of welfare of the experimental animals, and is also beneficial to implementation of various experimental teaching.
Drawings
Fig. 1 is a schematic structural diagram of a support frame according to an embodiment of the present invention.
Fig. 2 is a schematic structural diagram of an embodiment of the present invention.
In the drawings: 1-simulated rabbit for experiment, 2-charging interface, 3-positioner; 4-skull, 5-cervical vertebra, 6-thoracic vertebra, 7-rib, 8-lumbar vertebra, 9-femur, 10-ilium, 11-obturator foramen, 12-sacrum, 13-caudal vertebra, 14-ischium, 15-pubis, 16-tarsal bone, 17-metatarsal bone, 18-phalanx, 19-tibia, 20-fibula, 21-patella, 22-sternum, 23-carpal bone, 24-radius, 25-humerus, 26-ulna, 27-phalanx, 28-metacarpal bone, 29-acromion and 30-manubrium.
Detailed Description
Reference will now be made in detail to the exemplary embodiments, examples of which are illustrated in the accompanying drawings. When the following description refers to the accompanying drawings, like numbers in different drawings represent the same or similar elements unless otherwise indicated. The implementations described in the exemplary embodiments below are not intended to represent all implementations consistent with the present disclosure. Rather, they are merely examples of apparatus and methods consistent with certain aspects of the present disclosure, as detailed in the appended claims.
Referring to fig. 1, in an embodiment of the present invention, an experimental simulated rabbit 1 includes a supporting framework and a surface tissue mounted and connected to the supporting framework, wherein a temperature control module for controlling a surface temperature of the surface tissue is disposed in the surface tissue; a simulation organ is arranged in the supporting framework, and each unit of the simulation organ is modeled with each organ of the rabbit; the surface tissue corresponding to each unit of the simulated organ is provided with an opening and closing member, the opening and closing of the opening and closing member simulates anatomical movement, one side of the simulated organ far away from the opening and closing member is provided with a detection module, and the detection module is used for monitoring the state of the simulated organ and generating signals outwards.
Specifically, the surface tissue is made of thermoplastic elastomer mixed glue, the supporting framework is made of stainless steel materials, the inner part is hollow, the weight is reduced, and the weight of the real rabbit is simulated to the maximum extent. The opening and closing piece comprises zippers, and the zippers with different sizes are respectively arranged at the surface tissues corresponding to the units of the simulated organ and are used for realizing the simulation of the anatomical movement; the temperature control module comprises a heating wire and a temperature adjusting switch, and the power of the heating wire is adjusted through the temperature adjusting switch to enable the temperature of the surface tissue to reach 39 ℃; when arteriovenous puncture is carried out, the pressure values of all units of the simulated organ are monitored through the detection module, the relevant effect of an experiment is obtained by analyzing the pressure values, and when the pressure values of all units are abnormal, an outward signal is generated to remind experimenters to replace the abnormal units. The real rabbit is simulated to the maximum extent on the appearance, the body temperature and the hand feeling; the experimental operation experience is improved, the experimental teaching is facilitated, and meanwhile, experimental animals required by the experiment are reduced and replaced.
Referring to fig. 1, in the embodiment of the present invention, each joint of the support frame is movably connected by a connecting member.
Specifically, the support skeleton comprises a head support, a spine support, a chest support, a leg support and a tail support, wherein the head support comprises a skull 4; the vertebra support comprises a cervical vertebra 5, a thoracic vertebra 6, a lumbar vertebra 8, an ilium 10 and a sacrum 12 which are sequentially connected, wherein ribs 7 are arranged on the thoracic vertebra 6, and a closed hole 11 is arranged on the sacrum 12; the chest support comprises a sternum handle 30, a sternum 22 and a acromion 29; the leg support comprises a front leg unit and a rear leg unit, the front leg unit comprises a carpal bone 23, a radius 24, a humerus 25, an ulna 26, a phalanx 27 and a metacarpal bone 28; the hind leg unit comprises at least a femur 9, a patella 21 and juxtaposed fibulas 20 and tibias 19, as well as tarsal bones 16, metatarsals 17, phalanges 18 connected in sequence. The caudal support includes the ischial bones 14, the pubic bone 15, and the coccyx 13. The connecting piece comprises a pin and a connector, each support is connected with the connector through the pin, and each joint of the connecting part has at least two degrees of freedom; in the experimental teaching, the experimental operation of any body position is carried out.
Referring to fig. 1, in an embodiment of the present invention, the simulation organ at least includes: liver, kidney, bladder, heart and two lungs, and set up as: the liver is a source of venous pressure and is connected with a venous blood vessel; the kidney is the source of arterial pressure and is connected with an arterial blood vessel; the bladder is connected with a ureter; the heart comprises a right atrium, a right ventricle, a left atrium and a left ventricle which are composed of four cavities filled with different colors of pigments; and liquid with different colors is injected into the cavity of each unit of the simulation organ.
Specifically, the units of the simulated organ are made of silica gel, specifically soft silica gel, and can be repeatedly punctured for 300 times; the pressure balloon is filled with bright red pigment as kidney, and the pressure as arterial pressure source is 90-120 mmHg. The liver is used as venous pressure source, is filled with dark blue pigment under pressure of 8-10mmHg, and is convenient for supplementing liquid at any time via a pigment injection port arranged on the back side. The bladder is filled with transparent liquid, distilled water is only needed, the ureter connector is arranged and can be detached, the ureter can be detached and is provided with a multi-section connecting belt connector, and the bladder and the ureter can be repeatedly punctured for 200 times and 300 times. The heart is formed by 4 cavities which are not communicated with each other, and is injected with pigments with different colors, the right atrium is purple, the right ventricle is light blue, the left atrium is pink, the left ventricle is dark red, the color appearance is made by one-to-one simulation rabbit heart, and the pressure of the left ventricle is as follows: 110-130mmHg, the pressure of the right atrium (central venous pressure) is 8-10mmHg, the pressure of the right ventricle is 20-30mmHg, the left ventricle provides pressure for the left and right common carotid arteries, the right atrium provides pressure for the left and right external jugular veins, and a pigment injection opening arranged on the back side is convenient for fluid infusion at any time. The color and shape of the two lungs are made in a way that the color and shape of the two lungs are similar to those of a simulated rabbit lung, wherein the left lung is filled with light yellow liquid which is used as a heart injection indicating liquid, the right lung is filled with silica gel, and the two lungs can be detached. Each simulation organ with high simulation degree provides convenience for experiment operation, and the simulated rabbit 1 for experiments has wider applicable experiment projects.
In an optional embodiment of the present invention, the material for making each unit of the simulated organ is gel or a mixture of silica gel and gel. The puncture can be repeated 300 times.
In the embodiment of the invention, the simulation organ further comprises a rabbit ear, the root of the rabbit ear is detachably provided with a saccule, and the saccule is connected with the vein of the edge of the rabbit ear.
A small amount of dark red pigment is injected into the saccule, and the front side of the rabbit ear is also provided with a zipper, so that the saccule, a blood vessel connected with the vein and a connector can be conveniently replaced.
In the embodiment of the invention, a neck unit is arranged in the surface tissue and comprises a trachea, a common carotid artery and a common jugular vein, the trachea is connected with two lungs, and the common carotid artery and the common jugular vein are respectively connected with a left ventricle and a right atrium of a heart.
Specifically, the left ventricle and the right atrium provide pressure for the common carotid artery and the common jugular vein respectively, and the pressure of the common carotid artery and the common jugular vein is 90-120mmHg and 8-10mmHg respectively.
Furthermore, the lateral part of the common carotid artery is provided with a nerve, the nerve comprises a plurality of elastic parts with different diameters, and two ends of each elastic part are respectively hung on a hanging ring arranged on the surface tissue. The elastic piece is a nylon rope, and two ends of the three nylon ropes are integrally woven; the two sides of common carotid artery are provided with hooks, the two ends of the nylon rope are provided with iron rings, and the nylon rope is connected with the hooks through the iron rings.
In the embodiment of the present invention, as shown in fig. 2, the detection module comprises a power supply, an electronic baroreceptor, and the electronic baroreceptor is disposed on a side of the simulated organ away from the composite member, and is used for monitoring the state of the simulated organ and generating a signal outwards; the power supply provides electrical energy.
Specifically, the power supply is a lithium battery, the lithium battery is provided with a charging interface 2 for charging the lithium battery, and the electronic baroreceptors are respectively arranged on the back sides of the liver, the kidney, the bladder, the heart and the lungs and used for monitoring corresponding pressure values; and the pressure value is sent to the outside through the communication module.
Referring to fig. 2, in a preferred embodiment of the present invention, the present invention further includes a positioner 3 disposed in the supporting framework, and the positioner 3 sends a position signal thereof to the outside. The locator sets up in the skull of supporting the skeleton, fixes a position of experimental emulation rabbit of using in real time through the locator to rationally arrange the experiment.
The working principle of the invention is as follows: the zippers with different sizes are respectively arranged at the surface tissues corresponding to the units of the simulated organ and are used for realizing the simulation of the anatomical movement; the temperature control module comprises a heating wire and a temperature regulating switch, and the power of the heating wire is regulated through the temperature regulating switch, so that the temperature of surface tissues reaches 39 ℃, and the real body temperature of the rabbits is simulated; when arteriovenous puncture is carried out, the pressure values of all units of the simulated organ are monitored through the detection module, the relevant effect of an experiment is obtained by analyzing the pressure values, and when the pressure values of all units are abnormal, an outward signal is generated to remind experimenters to replace the abnormal units. The real rabbit is simulated to the maximum extent on the appearance, the body temperature and the hand feeling; the operation experience of the experiment is improved.
It should be noted that the electronic baroreceptors used in the present invention are prior art applications, and those skilled in the art can implement the intended functions according to the related description, or implement the technical features to be accomplished by similar techniques, and will not be described in detail herein.
Other embodiments of the disclosure will be apparent to those skilled in the art from consideration of the specification and practice of the disclosure herein. This application is intended to cover any variations, uses, or adaptations of the disclosure following, in general, the principles of the disclosure and including such departures from the present disclosure as come within known or customary practice within the art to which the disclosure pertains. It is intended that the specification and examples be considered as exemplary only, with a true scope and spirit of the disclosure being indicated by the following claims.
It will be understood that the present disclosure is not limited to the precise arrangements described above and shown in the drawings and that various modifications and changes may be made without departing from the scope thereof. The scope of the present disclosure is limited only by the appended claims.

Claims (10)

1. A simulated rabbit for experiments comprises a supporting framework and surface tissues which are arranged and connected on the supporting framework, and is characterized in that a temperature control module for controlling the surface temperature of the surface tissues is arranged in the surface tissues; a simulation organ is arranged in the supporting framework, and each unit of the simulation organ is modeled with each organ of the rabbit; the surface tissue corresponding to each unit of the simulated organ is provided with an opening and closing member, the opening and closing of the opening and closing member simulates anatomical movement, one side of the simulated organ far away from the opening and closing member is provided with a detection module, and the detection module is used for monitoring the state of the simulated organ and generating signals outwards.
2. The experimental simulated rabbit according to claim 1, wherein each joint of said supporting skeleton is movably connected by a connecting member.
3. The experimental rabbit according to claim 1, wherein said organs at least comprise: liver, kidney, bladder, heart and two lungs, and set up as: the liver is a source of venous pressure and is connected with a venous blood vessel; the kidney is the source of arterial pressure and is connected with an arterial blood vessel; the bladder is connected with a ureter; the heart comprises a right atrium, a right ventricle, a left atrium and a left ventricle which are composed of four cavities filled with pigments with different colors.
4. The experimental rabbit according to claim 1, wherein each unit of said simulated organ is made of one of the following materials: silica gel, silica gel and gel mixed material.
5. The experimental rabbit according to claim 1, wherein the chambers of the units of said artificial organ are filled with liquids with different colors.
6. The experimental simulated rabbit according to claim 1, wherein said simulated organ further comprises a rabbit ear, a balloon is detachably mounted on a root of said rabbit ear, and said balloon is connected to a vein on an ear edge of said rabbit ear.
7. The experimental simulated rabbit according to claim 1, wherein a neck unit is arranged in said surface tissue, and comprises a trachea, a common carotid artery and a common jugular vein, said trachea is connected with both lungs, and said common carotid artery and said common jugular vein are respectively connected with left ventricle and right atrium of heart.
8. The experimental rabbit according to claim 7, wherein the lateral part of the common carotid artery has a nerve, the nerve comprises a plurality of elastic members with different diameters, and two ends of the elastic members are respectively hung on the surface tissues.
9. The experimental rabbit according to claim 1, wherein said detection module comprises a power source, an electronic baroreceptor, said electronic baroreceptor is disposed on a side of said simulated organ away from said joint member for monitoring the status of said simulated organ and generating a signal; the power supply provides electrical energy.
10. The experimental simulated rabbit according to claim 1, further comprising a positioner disposed within said support skeleton, said positioner sending its position signal outwards.
CN202010840955.3A 2020-08-20 2020-08-20 Simulated rabbit for experiment Pending CN111816044A (en)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN201965829U (en) * 2010-12-30 2011-09-07 孙英贤 External heart model device
CN204576947U (en) * 2015-01-27 2015-08-19 徐立兴 Imitative rabbit auricular vein puncture exercise model
CN205405963U (en) * 2016-02-21 2016-07-27 张兆君 A human simulation model for performing operation training
US20190236983A1 (en) * 2018-01-30 2019-08-01 Cell Surgical Network Corporation System and method for acoustic wave induced traumatic brain injury
TWM591241U (en) * 2019-09-26 2020-02-21 財團法人亞洲大學 Digestive System Simulator
CN210721929U (en) * 2019-09-30 2020-06-09 中国人民解放军第四军医大学 Simulated vascular puncture simulation training device

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN201965829U (en) * 2010-12-30 2011-09-07 孙英贤 External heart model device
CN204576947U (en) * 2015-01-27 2015-08-19 徐立兴 Imitative rabbit auricular vein puncture exercise model
CN205405963U (en) * 2016-02-21 2016-07-27 张兆君 A human simulation model for performing operation training
US20190236983A1 (en) * 2018-01-30 2019-08-01 Cell Surgical Network Corporation System and method for acoustic wave induced traumatic brain injury
TWM591241U (en) * 2019-09-26 2020-02-21 財團法人亞洲大學 Digestive System Simulator
CN210721929U (en) * 2019-09-30 2020-06-09 中国人民解放军第四军医大学 Simulated vascular puncture simulation training device

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Application publication date: 20201023