CN111789930A

CN111789930A - Traditional Chinese medicine for treating old stomach diseases and preparation method thereof

Info

Publication number: CN111789930A
Application number: CN202010415854.1A
Authority: CN
Inventors: 刘洋
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-05-19
Filing date: 2020-05-19
Publication date: 2020-10-20

Abstract

The invention discloses a traditional Chinese medicine for treating chronic gastropathy and a preparation method thereof, wherein the traditional Chinese medicine comprises, by weight, 5-10% of Huachuan, 5-12% of Chinese yam, 5-13% of dried orange peel, 10-15% of poria cocos, 5-12% of ginseng, 8-16% of rhizoma polygonati, 5-15% of dendrobe, 2-5% of pseudo-ginseng, 2-5% of bletilla striata, 2-5% of cuttlebone, 2-8% of chicken's gizzard-membrane, 2-6% of leech, 2-5% of medicated leaven, 2-5% of hawthorn, 2-5% of anise, 3-5% of dried ginger, 2-5% of galangal, 2-5% of polygonatum, 2-5% of finger. The traditional Chinese medicine composition is prepared from pure traditional Chinese medicine components by a traditional process, has no side effect, no additive, precise compatibility, no cold or heat, mild medicine property, convenient taking, wide treatment range, high cure rate and short treatment course, and has better cure effect on patients with gastric ulcer, gastric erosion bleeding and epidemic gastritis.

Description

Traditional Chinese medicine for treating old stomach diseases and preparation method thereof

Technical Field

The invention belongs to the technical field of medicines, and particularly relates to a traditional Chinese medicine for treating old stomach diseases and a preparation method thereof.

Background

Gastritis is a common disease, and mainly includes two major types, namely acute gastritis and chronic gastritis.

The acute gastritis refers to acute inflammation of gastric mucosa caused by different causes, and can be clinically classified into simple, erosive, corrosive and purulent. If the main lesion is erosion and bleeding, it is called acute erosive hemorrhagic gastritis. Because the inflammation is mostly caused by drugs or acute emergencies, it is also called acute gastric mucosal damage, and is one of the common causes of acute upper gastrointestinal hemorrhage. The clinical manifestations of different types of acute gastritis are presented below.

Simple gastritis: the main symptoms are epigastric fullness, dull pain, anorexia, eructation, nausea and vomiting, the vomitus of severe patients is slightly bloody, leucocyte is increased, neutrophilic granulocytosis is, and gastric mucosa congestion, edema, exudation, macular hemorrhage or erosion and the like can be seen in endoscopy.

Erosive gastritis: the disease is acute, and the bleeding of the upper digestive tract is sudden in the primary disease process, which is manifested as hematemesis or dark stool. Endoscopic examination (especially in two days of disease) can result in erosion, bleeding or superficial ulcer of gastric mucosa, especially in high-level stomach.

Corrosive gastritis: after the corrosive agent is swallowed, the earliest symptoms are severe pain in the oral cavity, throat and middle, upper and lower abdomen, which are often accompanied by swallowing pain, dysphagia and frequent nausea and vomiting; patients with severe hematemesis and hematemesis may have collapse or shock.

Purulent gastritis: the clinical manifestations of the general septicopyemia and acute peritonitis are usually severe pain in the upper abdomen, shiver due to cold, high fever, tense muscles in the upper abdomen and obvious tenderness, and can be complicated with gastric perforation, peritonitis, thrombophlebitis and liver abscess. In the theory of traditional Chinese medicine, purulent gastritis belongs to the category of epigastric pain. According to the etiology and pathogenesis of the disease, the traditional Chinese medicine can be used for treating food stagnation, stomach harmonizing, adverse qi descending, heat clearing, detoxifying, dampness removing, qi tonifying, yin nourishing, blood cooling, bleeding stopping and the like.

While chronic gastritis refers to chronic inflammation or atrophic changes of gastric mucosa caused by different etiologies. The essence is that after repeated damage to the gastric mucosal epithelium, the mucosa is altered due to its specific regenerative capacity and eventually undergoes irreversible atrophy or even disappearance of the native gastric glands. The main causes of the attack are long-term dietary factors, drug stimulation, helicobacter pylori infection, autoimmune factors, duodenal fluid reflux and the like. The diagnosis of chronic gastritis includes: (1) the clinical manifestations are dyspepsia symptoms such as upper abdominal dull pain, anorexia, postprandial fullness, acid regurgitation and the like, atrophic gastritis patients can have anemia, emaciation, glossitis, diarrhea and the like, and individual patients with mucosa erosion have obvious upper abdominal pain and bleeding; (2) the corresponding changes in various types of gastritis can be seen by gastroscopy. In the theory of traditional Chinese medicine, the disease belongs to the category of epigastric pain, and can be generally treated by the methods of harmonizing the stomach and lowering the adverse flow of qi, soothing the liver and regulating qi, tonifying qi and strengthening the spleen, nourishing yin and harmonizing the stomach, promoting blood circulation to remove blood stasis, clearing heat and drying dampness, warming yang and dispelling cold and the like.

According to tissue classification, chronic gastritis can be generally classified into chronic superficial gastritis, chronic atrophic gastritis, chronic erosive gastritis, and bile reflux gastritis. The clinical manifestations of different kinds of chronic gastritis are presented below.

Chronic superficial gastritis: the main pathological changes are characterized by inflammatory cell infiltration in the lamina propria between the fovea, which is common in congestion, edema and even bleeding, and normal in the gastric gland.

Chronic atrophic gastritis: the pathological changes of the traditional Chinese medicine are not only the pathological changes of the chronic superficial gastritis, but also the lesions of the chronic superficial gastritis affect glands, the glands are atrophic, the number of the glands is reduced, and the mucous membrane muscles are thickened commonly; there is a varying degree of thinning of the gastric mucosa due to atrophy or disappearance of the glands.

Chronic erosive gastritis: it is often associated with peptic ulcer, superficial gastritis and atrophic gastritis, or occurs alone.

Bile reflux gastritis is a disease which causes pylorus to be continuously opened due to the reduction of the contractility of pyloric sphincter or other reasons, bile and alkaline intestinal juice flow back to stomach, and gastric mucosa barrier is damaged, so that the gastric mucosa is congested, edematous, erosive and even ulcerated.

When treating gastropathy, two modes of western medicine and traditional Chinese medicine are mainly adopted. The western medicine mainly aims at treating the symptoms, cannot treat the root causes, is difficult to completely and radically treat the stomach diseases, is easy to repeat after treatment, and particularly has difficult obvious effect on patients with reflux gastritis, gastric ulcer and gastric erosion bleeding, and the patients with gastric ulcer and gastric erosion bleeding can feel burning after taking the traditional Chinese medicine for treating the stomach diseases, thereby affecting the treatment effect.

Disclosure of Invention

The invention provides a traditional Chinese medicine for treating old stomach illness and a preparation method thereof, aiming at the problems in the prior art.

In order to achieve the purpose, the technical scheme provided by the invention is as follows:

the invention relates to a traditional Chinese medicine for treating chronic gastropathy, which comprises, by weight, 5-10% of Huachuan, 5-12% of Chinese yam, 5-13% of dried orange peel, 10-15% of poria cocos, 5-12% of ginseng, 8-16% of rhizoma polygonati, 5-15% of dendrobe, 2-5% of pseudo-ginseng, 2-5% of bletilla striata, 2-5% of cuttlebone, 2-8% of chicken's gizzard-membrane, 2-6% of leech, 2-5% of medicated leaven, 2-5% of hawthorn, 2-5% of anise, 3-5% of dried ginger, 2-5% of galangal, 2-5% of polygonatum odoratum, 2-5% of fingered citron and 2.

Preferably, the traditional Chinese medicine comprises, by weight, 8% of Huachuan, 9% of Chinese yam, 9% of dried orange peel, 11% of poria cocos, 9% of ginseng, 11% of rhizoma polygonati, 11% of dendrobium, 2% of pseudo-ginseng, 3% of bletilla striata, 3% of cuttlebone, 2% of endothelium corneum gigeriae galli, 3% of leech, 3% of medicated leaven, 3% of hawthorn, 2% of anise, 2% of dried ginger, 2% of galangal, 2% of radix polygonati officinalis, 2% of fingered citron.

A preparation method of a traditional Chinese medicine for treating old stomach illness comprises the following steps:

(1) parching HUACHUAN, pericarpium Citri Tangerinae, Zingiberis rhizoma and rhizoma Alpiniae Officinarum with wine respectively, pulverizing Poria and rhizoma Dioscoreae into powder respectively, stirring with vinegar, standing for 1-3 days, cleaning rhizoma Polygonati Odorati and herba Dendrobii, soaking for 3-7 days, steaming Ginseng radix and rhizoma Polygonati for nine times, and sun drying;

(2) respectively packaging the Huachuan, the Chinese yam, the dried orange peel, the poria cocos, the dendrobium, the aniseed, the dried ginger, the galangal, the polygonatum odoratum, the fingered citron and the amomum fruit in a medicine jar, sealing, and stewing for 20-30 hours by slow fire;

(3) after cooling, taking out the medicinal materials from the medicinal jar, and airing for 8-12 hours at the temperature of 10-35 ℃;

(4) respectively putting the dried medicinal materials into a wooden steamer, standing the wooden steamer in a water-proof manner, continuously steaming for 12-16 hours, taking out, drying in the sun and drying;

(5) mixing the dried medicinal materials with Ginseng radix, pulverizing into powder, adding Notoginseng radix, rhizoma Bletillae, Os Sepiae, endothelium corneum Gigeriae Galli, Hirudo, Massa Medicata Fermentata, and fructus crataegi which have been pulverized into powder, and making into pill.

Preferably, in the step (2), slow fire roasting is carried out on the open air, a round surrounding stove is built by using bricks, the straw and the bran coat are ignited in the surrounding stove of the medicine jar, and the slow fire roasting time is 24 hours.

Preferably, in the step (3), the airing time is 10 hours, and the airing temperature is 22 ℃.

Preferably, in the step (4), the pot is kept water-proof, and the continuous steaming time is 14 hours.

Ginseng: has effects of invigorating primordial qi, invigorating spleen, benefiting lung, and promoting fluid production.

Rhizoma polygonati: has effects of nourishing yin, moistening lung, invigorating spleen, invigorating qi, replenishing kidney essence, and replenishing essence.

Dendrobe: has the effects of nourishing stomach yin, promoting the production of body fluid and quenching thirst, and can clear stomach heat and clear heat accumulated in stomach assisted by polygonatum.

Tuckahoe, poria cocos: has the effects of inducing diuresis to alleviate edema, excreting dampness, strengthening the spleen and calming the heart, and the galangal, the yam and the amomum villosum are used for strengthening the spleen and the stomach and eliminating the dampness in the stomach for the spleen deficiency and the diarrhea.

Dried orange peel: has the effects of regulating qi, strengthening spleen, eliminating dampness and phlegm. Mainly for vomiting due to qi stagnation of spleen and stomach, hiccup is accompanied by finger citron to move qi and remove stomach distension.

And (4) Huachuan: has effects of promoting blood circulation, removing blood stasis, dispelling cold and relieving pain. The aniseed dried ginger is added to the decoction to remove cold and dampness in stomach and relieve pain.

Compared with the prior art, the technical scheme provided by the invention has the following beneficial effects:

1. the traditional Chinese medicine is prepared from pure traditional Chinese medicine components by a traditional process, has no side effect, no additive, precise compatibility, no cold or heat, mild medicine property, convenient taking, wide treatment range, high cure rate and short treatment course.

2. The cuttlebone, the pseudo-ginseng and the bletilla striata in the invention have good curative effects on gastric ulcer and gastric erosion bleeding patients, and burning sensation cannot occur after the medicine is taken.

3. The endothelium corneum gigeriae galli, the leech, the medicated leaven and the hawthorn in the traditional Chinese medicine composition have a good curative effect on patients with reflux gastritis.

Detailed Description

For further understanding of the present invention, the present invention will be described in detail with reference to examples, which are provided for illustration of the present invention but are not intended to limit the scope of the present invention.

Example 1

The embodiment relates to a traditional Chinese medicine for treating chronic gastropathy, which comprises, by weight, 7% of Huachuan, 8% of Chinese yam, 8% of dried orange peel, 10% of poria cocos, 8% of ginseng, 10% of rhizoma polygonati, 10% of dendrobe, 3% of pseudo-ginseng, 3% of bletilla striata, 3% of cuttlebone, 3% of endothelium corneum gigeriae galli, 5% of leech, 5% of medicated leaven, 5% of hawthorn, 2% of anise, 2% of dried ginger, 2% of galangal, 2% of radix polygonati officinalis, 2% of fingered.

The preparation method of the traditional Chinese medicine for treating the old stomach illness comprises the following steps:

(1) parching HUACHUAN, pericarpium Citri Tangerinae, Zingiberis rhizoma, and rhizoma Alpiniae Officinarum with wine respectively, pulverizing Poria and rhizoma Dioscoreae into powder respectively, stirring with vinegar, standing for 2 days, cleaning rhizoma Polygonati Odorati and herba Dendrobii, soaking for 5 days, steaming Ginseng radix and rhizoma Polygonati for nine times, and sun drying;

(2) respectively packaging HUACHUAN, rhizoma Dioscoreae, pericarpium Citri Tangerinae, Poria, herba Dendrobii, fructus Anisi Stellati, Zingiberis rhizoma, rhizoma Alpiniae Officinarum, rhizoma Polygonati Odorati, fructus Citri Sarcodactylis and fructus Amomi in a jar, sealing, and slowly stewing for 24 hr with slow fire;

(3) cooling, taking out the medicinal materials from the medicinal jar, and air-drying for 10 hr at 22 deg.C;

(4) respectively putting the dried medicinal materials into a wooden steamer, standing in a pot, continuously steaming for 14 hours, taking out, drying in the sun and drying;

(5) mixing the dried medicinal materials with Ginseng radix and rhizoma Polygonati, pulverizing into powder, adding Notoginseng radix, rhizoma Bletillae, Os Sepiae, endothelium corneum Gigeriae Galli, Hirudo, Massa Medicata Fermentata, and fructus crataegi which have been pulverized into powder, and making into pill.

The slow fire stewing is carried out by building a round surrounding stove by bricks on an open air ground, putting the straw and the bran coat in the surrounding stove of a medicine jar, and slowly stewing with slow fire.

Example 2

The embodiment relates to a traditional Chinese medicine for treating chronic gastropathy, which comprises, by weight, 7% of Huachuan, 8% of Chinese yam, 8% of dried orange peel, 10% of poria cocos, 8% of ginseng, 10% of rhizoma polygonati, 10% of dendrobe, 2% of pseudo-ginseng, 3% of bletilla striata, 3% of cuttlebone, 2% of endothelium corneum gigeriae galli, 3% of leech, 4% of medicated leaven, 4% of hawthorn, 3% of anise, 3% of dried ginger, 3% of galangal, 3% of radix polygonati officinalis, 3% of fingered.

Example 3

The embodiment relates to a traditional Chinese medicine for treating chronic gastropathy, which comprises, by weight, 8% of Huachuan, 9% of Chinese yam, 9% of dried orange peel, 11% of poria cocos, 9% of ginseng, 11% of rhizoma polygonati, 11% of dendrobe, 2% of pseudo-ginseng, 3% of bletilla striata, 3% of cuttlebone, 2% of endothelium corneum gigeriae galli, 3% of leech, 3% of medicated leaven, 3% of hawthorn, 2% of anise, 2% of dried ginger, 2% of galangal, 2% of radix polygonati officinalis, 2% of fingered.

Example 4

Example 5

The embodiment relates to a traditional Chinese medicine for treating chronic gastropathy, which comprises, by weight, 8% of Huachuan, 9% of Chinese yam, 9% of dried orange peel, 10% of poria cocos, 10% of ginseng, 12% of rhizoma polygonati, 12% of dendrobe, 2% of pseudo-ginseng, 3% of bletilla striata, 3% of cuttlebone, 2% of endothelium corneum gigeriae galli, 3% of leech, 4% of medicated leaven, 4% of hawthorn, 2% of anise, 2% of dried ginger, 2% of galangal, 2% of radix polygonati officinalis, 2% of fingered.

Example 6

The embodiment relates to a traditional Chinese medicine for treating chronic gastropathy, which comprises, by weight, 10% of Huachuan, 5% of Chinese yam, 5% of dried orange peel, 15% of poria cocos, 5% of ginseng, 10% of rhizoma polygonati, 5% of dendrobe, 4% of pseudo-ginseng, 4% of bletilla striata, 4% of cuttlebone, 4% of endothelium corneum gigeriae galli, 4% of leech, 4% of medicated leaven, 4% of hawthorn, 3% of anise, 4% of dried ginger, 2% of galangal, 3% of radix polygonati officinalis, 3% of fingered.

Example 7

The embodiment relates to a traditional Chinese medicine for treating chronic gastropathy, which comprises, by weight, 5% of Huachuan, 5% of Chinese yam, 5% of dried orange peel, 10% of poria cocos, 12% of ginseng, 11% of rhizoma polygonati, 5% of dendrobe, 5% of pseudo-ginseng, 5% of bletilla striata, 5% of cuttlebone, 5% of endothelium corneum gigeriae galli, 5% of leech, 5% of medicated leaven, 5% of hawthorn, 2% of anise, 2% of dried ginger, 2% of galangal, 2% of radix polygonati officinalis, 2% of fingered.

In the comparative example 1,

the traditional Chinese medicine comprises, by weight, 5% of Huachuan, 5% of Chinese yam, 5% of dried orange peel, 10% of poria cocos, 12% of ginseng, 16% of rhizoma polygonati, 15% of dendrobe, 5% of endothelium corneum gigeriae galli, 3% of leech, 4% of medicated leaven, 4% of hawthorn, 3% of anise, 2% of dried ginger, 3% of galangal, 2% of polygonatum odoratum, 3% of fingered citron and 3% of fructus amomi.

(5) mixing the dried medicinal materials with Ginseng radix and rhizoma Polygonati, pulverizing into powder, adding endothelium corneum Gigeriae Galli, Hirudo, Massa Medicata Fermentata, and fructus crataegi, and making into pill.

Comparative example 2

The traditional Chinese medicine comprises, by weight, 10% of Huachuan, 10% of Chinese yam, 5% of dried orange peel, 10% of poria cocos, 12% of ginseng, 16% of rhizoma polygonati, 5% of dendrobe, 5% of pseudo-ginseng, 5% of bletilla striata, 5% of cuttlebone, 2% of anise, 3% of dried ginger, 3% of galangal, 3% of polygonatum odoratum, 3% of fingered citron and 3% of fructus amomi.

(5) mixing the dried medicinal materials with Ginseng radix and rhizoma Polygonati, pulverizing into powder, adding Notoginseng radix, rhizoma Bletillae and Os Sepiae, and making into pill.

Comparative example 3

The traditional Chinese medicine comprises, by weight, 10% of Huachuan, 10% of Chinese yam, 10% of dried orange peel, 10% of poria cocos, 10% of ginseng, 10% of rhizoma polygonati, 10% of dendrobe, 5% of anise, 5% of dried ginger, 5% of galangal, 5% of radix polygonati officinalis, 5% of fingered citron and 5% of fructus amomi.

(5) mixing the dried medicinal materials with Ginseng radix and rhizoma Polygonati, pulverizing into powder, and making into pill.

Effects of the embodiment

The therapeutic effects of the above-mentioned traditional Chinese medicine pellets in comparative examples 1 to 3 and examples 1 to 6 are shown in table 1.

TABLE 1

The best therapeutic effect is achieved by the ratio of the components in example 3 as can be seen from table 1.

In order to further understand the practical use effect of the invention, the traditional Chinese medicine pills are prepared according to the component proportion in the embodiment 3, 40 days are a treatment course, the traditional Chinese medicine pills are taken once a day before sleep, patients suffering from reflux gastritis are taken by tea oil, 270 patients suffering from stomach diseases are treated, 236 patients are cured, 2 patients are not treated, 166 patients suffering from chronic superficial gastritis are treated, 140 patients are cured, 26 patients suffering from obvious gastritis are treated, 20 patients suffering from atrophic gastritis are treated, 18 patients are cured, 2 patients suffering from obvious gastritis are treated, 24 patients suffering from erosive gastritis are treated, 20 patients are cured, 4 patients suffering from obvious gastritis are treated, 60 patients suffering from bile reflux gastritis are treated, 52 patients are cured, 6 patients suffering from obvious gastritis are treated, and 2 patients are not treated.

In conclusion, the invention has remarkable effect on treating chronic superficial gastritis, atrophic gastritis, erosive gastritis and bile reflux gastritis.

The present invention and its embodiments have been described above schematically, the description is not intended to be limiting, the embodiments shown in the examples are merely embodiments of the present invention, and the actual structure is not limited thereto. Therefore, those skilled in the art should understand that they can easily and effectively design and modify the structure and embodiments of the present invention without departing from the spirit and scope of the present invention.

Claims

1. The traditional Chinese medicine for treating the old stomach diseases is characterized by comprising, by weight, 5-10% of Huachuan, 5-12% of Chinese yam, 5-13% of dried orange peel, 10-15% of poria cocos, 5-12% of ginseng, 8-16% of rhizoma polygonati, 5-15% of dendrobe, 2-5% of pseudo-ginseng, 2-5% of bletilla striata, 2-5% of cuttlebone, 2-8% of chicken's gizzard-membrane, 2-6% of leech, 2-5% of medicated leaven, 2-5% of hawthorn, 2-5% of anise, 3-5% of dried ginger, 2-5% of galangal, 2-5% of polygonatum odoratum, 2-5% of fingered citron and 2-5.

2. The traditional Chinese medicine for treating the old stomach illness according to claim 1, wherein the traditional Chinese medicine is composed of, by weight, 8% of Huachuan, 9% of Chinese yam, 9% of dried orange peel, 11% of poria cocos, 9% of ginseng, 11% of rhizoma polygonati, 11% of dendrobe, 2% of pseudo-ginseng, 3% of bletilla striata, 3% of cuttlebone, 2% of endothelium corneum gigeriae galli, 3% of leech, 3% of medicated leaven, 3% of hawthorn, 2% of anise, 2% of dried ginger, 2% of galangal, 2% of polygonatum odoratum, 2% of.

3. A method for preparing the traditional Chinese medicine for treating the old stomach illness as claimed in claim 1, which is characterized by comprising the following steps:

4. The method for preparing a traditional Chinese medicine for treating old stomach illness according to claim 3, characterized in that in the step (2), slow fire is carried out on the open air, a round surrounding stove is built by using bricks, and rice straws and rice bran are placed on the surrounding stove of the medicine jar, slowly fire is carried out on the rice straws and the rice bran for 24 hours.

5. The method for preparing a traditional Chinese medicine for treating old stomach illness according to claim 3, wherein in the step (3), the airing time is 10 hours, and the airing temperature is 22 ℃.

6. The method for preparing a traditional Chinese medicine for treating old stomach illness according to claim 3, wherein in the step (4), the pot is set in a water-proof manner, and the continuous steaming time is 14 hours.