CN111773290A - Traditional Chinese medicine compound for treating blood vessel stasis diseases and preparation method thereof - Google Patents
Traditional Chinese medicine compound for treating blood vessel stasis diseases and preparation method thereof Download PDFInfo
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- CN111773290A CN111773290A CN202010887804.3A CN202010887804A CN111773290A CN 111773290 A CN111773290 A CN 111773290A CN 202010887804 A CN202010887804 A CN 202010887804A CN 111773290 A CN111773290 A CN 111773290A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/55—Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
The invention discloses a traditional Chinese medicine compound for treating vascular stasis diseases, which is prepared from the following components in parts by weight: 2800-3200 parts of ginseng extract, 3700-4300 parts of salvia miltiorrhiza extract, 2900-3000 parts of saffron and 40-60 parts of musk; based on holism, the invention exerts the advantages of differential treatment of traditional Chinese medicine, selects pure natural medicines for compatibility, ensures that the traditional Chinese medicine compound has excellent efficacies of tonifying qi, stimulating the menstrual flow, promoting blood circulation, removing plaque and the like, and has obvious curative effects on arteriosclerosis, cerebral infarction, hyperlipidemia and coronary arteriosclerotic heart disease.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicine compounds, in particular to a traditional Chinese medicine compound for treating vascular stasis diseases and a preparation method thereof.
Background
Coronary atherosclerotic heart disease is a heart disease caused by myocardial ischemia, hypoxia or necrosis due to stenosis or obstruction of a blood vessel cavity caused by atherosclerotic lesions generated in coronary vessels.
Cerebral infarction is also called ischemic stroke, which is called stroke or stroke in traditional Chinese medicine; the disease is caused by blood supply disorder of local brain tissue areas caused by various reasons, and the ischemic and hypoxic lesion necrosis of the brain tissue is caused, so that the clinically corresponding nerve function deficiency expression is generated. Cerebral infarction is divided into main types such as cerebral thrombosis, cerebral embolism, lacunar infarction and the like according to different pathogenesis.
Arteriosclerosis is a non-inflammatory lesion of an artery, and can thicken and harden the wall of an artery, lose elasticity and narrow a lumen; arteriosclerosis is a vascular disease which appears with age, and the rule is that the arteriosclerosis usually occurs in teenagers and aggravates and attacks the middle-aged and the elderly; the main causes of arteriosclerosis are that a large amount of greasy food and food rich in cholesterol are taken by cholesterol, which is the main reason of arteriosclerosis occurrence, the content of cholesterol in blood is excessive, which is an important risk factor for coronary arteriosclerosis occurrence, and in addition, a certain amount of grease is generally contained in daily diet, and if the people like to eat greasy food at ordinary times and do not pay attention to the intake of other minerals, the excessive grease is deposited on the vessel wall, and arteriosclerosis and other cardiovascular diseases are induced.
At present, the medicines for treating the blood vessel stasis disease comprise traditional Chinese medicines and western medicines, however, the western medicines have large toxic and side effects and are easy to cause certain damage to body organs (such as liver, kidney and the like); the existing traditional Chinese medicine has long treatment period and poor effect.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine compound for treating the diseases of blood vessel stasis, which has excellent efficacies of tonifying qi, dredging channels, removing blood spots and the like and has obvious curative effects on arteriosclerosis, cerebral infarction, hyperlipidemia and coronary arteriosclerotic heart disease.
In order to achieve the above purpose of the present invention, the following technical solutions are adopted:
the invention provides a traditional Chinese medicine compound for treating vascular stasis diseases, which is prepared from the following components in parts by weight:
2800-3200 parts of ginseng extract, 3700-4300 parts of salvia miltiorrhiza extract, 2900-3000 parts of saffron and 40-60 parts of musk.
Preferably, the traditional Chinese medicine compound is prepared from the following components in parts by weight:
3000 parts of ginseng extract, 4000 parts of salvia extract, 2950 parts of saffron and 50 parts of musk.
The invention is based on holism concept, exerts the advantages of differential treatment of traditional Chinese medicine, selects pure natural medicines to be compatible according to the principle of monarch, minister, assistant and guide, and has the following main medicines: the ginseng is selected from northeast ginseng or Korean ginseng, is sweet and mild in nature and slightly bitter in taste, enters spleen, lung and heart channels, has the effects of greatly tonifying primordial qi, regulating and tonifying qi deficiency of five internal organs, treating ying and wei qi deficiency and the like, and has a good treatment effect on hypertension, myocardial malnutrition, coronary arteriosclerosis, angina pectoris and the like through modern pharmacology; ministerial drugs: salvia miltiorrhiza, slightly cold in nature and bitter in taste, enters heart and liver meridians; has the effects of removing blood stasis, relieving pain, promoting blood circulation, stimulating the menstrual flow, clearing away the heart-fire and relieving restlessness, and comprises the following components in part by weight: the modern researches suggest that the red sage drink, namely one Danshen decoction, is equivalent to the four-ingredient decoction, contains various tanshinones, has the effects of diluting blood and eliminating abnormal hyperplasia of tissues, and has prominent effects on chronic coronary ischemic lesions and thrombotic occlusive diseases; adjuvant drugs: saffron is a fine product in safflower, has mild nature and sweet taste, enters heart meridian, has the effects of promoting blood circulation to remove blood stasis, dispersing stagnation and resolving masses, improving specific efficacy and the like, can be used for various patients with different constitutions, is frequently selected by physicians in the past for treating diseases caused by blood stasis, and has obvious anti-hemagglutination effect proved by modern pharmacology; a messenger drug: musk is warm in nature, pungent in taste, strong in fragrance and particularly good for dredging brain and entering heart, is a famous and precious product for inducing resuscitation, dredging collaterals, dissipating blood stasis, relieving swelling and pain in traditional Chinese medicine all the time, is mostly used for treating infarction diseases such as apoplexy, coma, amenorrhea and abdominal mass, arthralgia and numbness and the like, and researches prove that musk can directly act on a central nervous system through a blood brain barrier, excites the electrical activity of cerebral cortex and has an obvious awakening effect on central nerve inhibition; increasing anoxia resistance of heart and brain, and preventing and treating ischemic heart disorder caused by thrombosis; the compatible Chinese herbal compound has excellent efficacies of tonifying qi, stimulating the menstrual flow, regulating blood circulation, removing plaque and the like, and has obvious curative effects on arteriosclerosis, cerebral infarction, hyperlipidemia and coronary arteriosclerotic heart disease.
Preferably, the musk is artificial musk.
Preferably, the vascular fouling diseases include arteriosclerosis, hyperlipidemia, cerebral infarction and coronary arteriosclerotic heart disease.
Preferably, the preparation method of the traditional Chinese medicine compound comprises the following steps:
respectively pulverizing stigma croci Sativi and Moschus to obtain stigma croci Sativi powder and Moschus powder;
mixing stigma croci Sativi powder, Ginseng radix extract, and Saviae Miltiorrhizae radix extract to obtain mixture;
and (3) putting the musk powder into the mixture, uniformly mixing, sterilizing and packaging to obtain the traditional Chinese medicine compound.
Preferably, the stigma croci Sativi powder has a mesh size of not less than 250 mesh.
Preferably, the granularity of the musk powder is not less than 300 meshes.
Preferably, the sterilization is CO60 irradiation sterilization.
Preferably, the amount of the Chinese herbal compound medicine in each bag is 2 g.
Compared with the prior art, the invention has the beneficial effects that at least:
the invention is based on holism concept, exerts the advantages of differential treatment of traditional Chinese medicine, selects pure natural medicines to be compatible according to the principle of monarch, minister, assistant and guide, and has the following main medicines: the ginseng is selected from northeast ginseng or Korean ginseng, is sweet and mild in nature and slightly bitter in taste, enters spleen, lung and heart channels, has the effects of greatly tonifying primordial qi, regulating and tonifying qi deficiency of five internal organs, treating ying and wei qi deficiency and the like, and has a good treatment effect on hypertension, myocardial malnutrition, coronary arteriosclerosis, angina pectoris and the like through modern pharmacology; ministerial drugs: salvia miltiorrhiza, slightly cold in nature and bitter in taste, enters heart and liver meridians; has the effects of removing blood stasis, relieving pain, promoting blood circulation, stimulating the menstrual flow, clearing away the heart-fire and relieving restlessness, and comprises the following components in part by weight: the modern researches suggest that the red sage drink, namely one Danshen decoction, is equivalent to the four-ingredient decoction, contains various tanshinones, has the effects of diluting blood and eliminating abnormal hyperplasia of tissues, and has prominent effects on chronic coronary ischemic lesions and thrombotic occlusive diseases; adjuvant drugs: saffron is a fine product in safflower, has mild nature and sweet taste, enters heart meridian, has the effects of promoting blood circulation to remove blood stasis, dispersing stagnation and resolving masses, improving specific efficacy and the like, can be used for various patients with different constitutions, is frequently selected by physicians in the past for treating diseases caused by blood stasis, and has obvious anti-hemagglutination effect proved by modern pharmacology; a messenger drug: musk is warm in nature, pungent in taste, strong in fragrance and particularly good for dredging brain and entering heart, is a famous and precious product for inducing resuscitation, dredging collaterals, dissipating blood stasis, relieving swelling and pain in traditional Chinese medicine all the time, is mostly used for treating infarction diseases such as apoplexy, coma, amenorrhea and abdominal mass, arthralgia and numbness and the like, and researches prove that musk can directly act on a central nervous system through a blood brain barrier, excites the electrical activity of cerebral cortex and has an obvious awakening effect on central nerve inhibition; increasing anoxia resistance of heart and brain, and preventing and treating ischemic heart disorder caused by thrombosis; the compatible Chinese herbal compound has excellent efficacies of tonifying qi, stimulating the menstrual flow, regulating blood circulation, removing plaque and the like, and has obvious curative effects on arteriosclerosis, cerebral infarction, hyperlipidemia and coronary arteriosclerotic heart disease.
Detailed Description
The following describes embodiments of the present invention in detail with reference to the following embodiments. The following examples are only for illustrating the technical solutions of the present invention more clearly, and therefore are only examples, and the protection scope of the present invention is not limited thereby.
It is to be noted that, unless otherwise specified, technical or scientific terms used herein shall have the ordinary meaning as understood by those skilled in the art to which the invention pertains.
Example 1
Chinese herbal compound for treating blood vessel stasis disease
The traditional Chinese medicine compound for treating the blood vessel stasis disease is prepared from the following components in parts by weight:
3200 parts of ginseng extract, 3700 parts of salvia miltiorrhiza extract, 3000 parts of saffron and 40 parts of musk.
Second, preparation method
The preparation method of the traditional Chinese medicine compound for treating the blood vessel stasis disease comprises the following steps:
respectively crushing saffron and musk to obtain saffron powder and musk powder, wherein the granularity of the saffron powder is not less than 250 meshes, and the granularity of the musk powder is not less than 300 meshes;
mixing stigma croci Sativi powder, Ginseng radix extract, and Saviae Miltiorrhizae radix extract to obtain mixture;
mixing Moschus powder with the mixture, sterilizing by CO60 irradiation, and packaging to obtain Chinese medicinal composition for treating blood vessel stasis.
Example 2
Chinese herbal compound for treating blood vessel stasis disease
The traditional Chinese medicine compound for treating the blood vessel stasis disease is prepared from the following components in parts by weight:
2800 parts of ginseng extract, 4300 parts of salvia extract, 2900 parts of saffron and 60 parts of musk.
Second, preparation method
The preparation method of the traditional Chinese medicine compound for treating the blood vessel stasis disease comprises the following steps:
respectively crushing saffron and musk to obtain saffron powder and musk powder, wherein the granularity of the saffron powder is not less than 250 meshes, and the granularity of the musk powder is not less than 300 meshes;
mixing stigma croci Sativi powder, Ginseng radix extract, and Saviae Miltiorrhizae radix extract to obtain mixture;
mixing Moschus powder with the mixture, sterilizing by CO60 irradiation, and packaging to obtain Chinese medicinal composition for treating blood vessel stasis.
Example 3
Chinese herbal compound for treating blood vessel stasis disease
The traditional Chinese medicine compound for treating the blood vessel stasis disease is prepared from the following components in parts by weight:
3000 parts of ginseng extract, 4000 parts of salvia extract, 2950 parts of saffron and 50 parts of musk.
Second, preparation method
The preparation method of the traditional Chinese medicine compound for treating the blood vessel stasis disease comprises the following steps:
respectively crushing saffron and musk to obtain saffron powder and musk powder, wherein the granularity of the saffron powder is not less than 250 meshes, and the granularity of the musk powder is not less than 300 meshes;
mixing stigma croci Sativi powder, Ginseng radix extract, and Saviae Miltiorrhizae radix extract to obtain mixture;
mixing Moschus powder with the mixture, sterilizing by CO60 irradiation, and packaging to obtain Chinese medicinal composition for treating blood vessel stasis.
The traditional Chinese medicine compound disclosed by the embodiment of the invention is based on the holism concept, exerts the advantages of syndrome differentiation and treatment of traditional Chinese medicine, and selects pure natural medicines for compatibility, so that the traditional Chinese medicine compound has excellent effects of tonifying qi, dredging channels, removing blood spots and the like, and has obvious curative effects on arteriosclerosis, cerebral infarction, hyperlipidemia and coronary arteriosclerotic heart disease.
Comparative example 1
The control example is a traditional Chinese medicine compound for treating the blood vessel stasis disease, and the traditional Chinese medicine compound is basically the same as the traditional Chinese medicine compound in the embodiment 3, and is different only in that musk is replaced by the ginseng extract with the same weight part.
The preparation method of the traditional Chinese medicine compound is the same as that in the embodiment 3.
Comparative example 2
The control example is a traditional Chinese medicine compound for treating the blood vessel stasis disease, and the traditional Chinese medicine compound is prepared from the following components in parts by weight:
3500 parts, 3500 parts of salvia extract, 2950 parts of saffron and 5 parts of musk.
The preparation method of the traditional Chinese medicine compound is the same as that in the embodiment 3.
Examples of the experiments
Randomly selecting 130 patients with arteriosclerosis, wherein each patient has at least 3 symptoms of chest distress, headache, dizziness, cold and numb limbs and lameness; the patients are 48-67 years old, and the average disease duration is 1.4 years; all the subjects are randomly divided into 5 groups, each group contains 26 persons, and each group of patients respectively take the traditional Chinese medicine compound in the embodiment 1-3 and the comparative example 1-2 of the invention for 3 times a day, and each time is 1 bag (2 g); after 2 months of administration, the visit was returned and recorded.
And (3) judging the curative effect:
the effect is shown: disappearance of at least two symptoms;
the method has the following advantages: at least one symptom is alleviated;
and (4) invalidation: no change in symptoms, or the presence of exacerbating symptoms.
The treatment results are shown in table 1:
TABLE 1
As can be seen from Table 1:
compared with the traditional Chinese medicine compound in the comparative example, the traditional Chinese medicine compound prepared by the embodiment of the invention has better treatment effect.
Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; such modifications and substitutions do not depart from the spirit and scope of the present invention, and they should be construed as being included in the following claims and description.
Claims (9)
1. A traditional Chinese medicine compound for treating blood vessel stasis diseases is characterized by being prepared from the following components in parts by weight:
2800-3200 parts of ginseng extract, 3700-4300 parts of salvia miltiorrhiza extract, 2900-3000 parts of saffron and 40-60 parts of musk.
2. The traditional Chinese medicine compound of claim 1, which is prepared from the following components in parts by weight:
3000 parts of ginseng extract, 4000 parts of salvia extract, 2950 parts of saffron and 50 parts of musk.
3. The compound traditional Chinese medicine according to claim 1 or 2, wherein the musk is an artificial musk.
4. The compound Chinese medicine according to claim 1 or 2, wherein the diseases of blood vessel stasis include arteriosclerosis, hyperlipidemia, cerebral infarction and coronary arteriosclerotic heart disease.
5. The preparation method of the traditional Chinese medicine compound recipe according to any one of claims 1 to 4, characterized by comprising the following steps:
respectively pulverizing stigma croci Sativi and Moschus to obtain stigma croci Sativi powder and Moschus powder;
mixing stigma croci Sativi powder, Ginseng radix extract, and Saviae Miltiorrhizae radix extract to obtain mixture;
and (3) putting the musk powder into the mixture, uniformly mixing, sterilizing and packaging to obtain the traditional Chinese medicine compound.
6. The method according to claim 5, wherein the saffron powder has a mesh size of not less than 250 mesh.
7. A method as claimed in claim 5, wherein said musk powder has a mesh size of not less than 300 mesh.
8. The method of claim 5, wherein the sterilization is CO60 radiation sterilization.
9. The preparation method according to claim 1, wherein the amount of the Chinese herbal compound medicine per bag is 2 g.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010887804.3A CN111773290A (en) | 2020-08-28 | 2020-08-28 | Traditional Chinese medicine compound for treating blood vessel stasis diseases and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202010887804.3A CN111773290A (en) | 2020-08-28 | 2020-08-28 | Traditional Chinese medicine compound for treating blood vessel stasis diseases and preparation method thereof |
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| Publication Number | Publication Date |
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| CN111773290A true CN111773290A (en) | 2020-10-16 |
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| CN202010887804.3A Pending CN111773290A (en) | 2020-08-28 | 2020-08-28 | Traditional Chinese medicine compound for treating blood vessel stasis diseases and preparation method thereof |
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- 2020-08-28 CN CN202010887804.3A patent/CN111773290A/en active Pending
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