CN111773283A - Traditional Chinese medicine composition for treating chronic nephritis - Google Patents

Traditional Chinese medicine composition for treating chronic nephritis Download PDF

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Publication number
CN111773283A
CN111773283A CN202010792317.9A CN202010792317A CN111773283A CN 111773283 A CN111773283 A CN 111773283A CN 202010792317 A CN202010792317 A CN 202010792317A CN 111773283 A CN111773283 A CN 111773283A
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parts
treating chronic
chronic nephritis
traditional chinese
chinese medicine
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仲崇允
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/40Cornaceae (Dogwood family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/24Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/39Convolvulaceae (Morning-glory family), e.g. bindweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482Cassia, e.g. golden shower tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/78Saururaceae (Lizard's-tail family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention discloses a traditional Chinese medicine composition for treating chronic nephritis, which is prepared from the following raw material medicines in parts by weight: 3-6 parts of medulla Tetrapanacis and senna; 6-12 parts of dogbane leaf and one piece of silk; 9-18 parts of momordica grosvenori and sambucus chinensis; 15-30 parts of true plates, saururus chinensis and ludwigia prostrata. The invention has the characteristics of obvious treatment effect, short treatment period, no toxic or side effect and the like.

Description

Traditional Chinese medicine composition for treating chronic nephritis
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating chronic nephritis.
Background
Chronic nephritis refers to a group of glomerulopathy with proteinuria, hematuria, hypertension and edema as basic clinical manifestations, different onset modes, prolonged disease state, slow progression of pathological changes, renal hypofunction in different degrees and finally chronic renal failure. The main clinical manifestations are different due to different pathological types and disease stages of the disease, and the disease manifestations are diversified.
Chronic glomerulonephritis is mainly aimed at preventing or delaying progressive worsening of renal function, improving or alleviating clinical symptoms, and preventing and treating complications. Whether to use glucocorticoid and cytotoxic drugs is determined according to etiology and pathological type. At present, no specific medicine for curing chronic nephritis exists.
Disclosure of Invention
The invention aims to improve the defects of the prior art and provides the traditional Chinese medicine composition for treating chronic nephritis, which has the characteristics of obvious treatment effect, short treatment period, no toxic or side effect and the like.
The technical scheme of the invention is as follows: an oral traditional Chinese medicine for treating chronic nephritis comprises the following raw material medicines in parts by weight: 3-6 parts of medulla Tetrapanacis and senna; 6-12 parts of dogbane leaf and one piece of silk; 9-18 parts of momordica grosvenori and sambucus chinensis; 15-30 parts of true plates, saururus chinensis and ludwigia prostrata.
In a preferred embodiment, the traditional Chinese medicine composition for treating chronic nephritis consists of the following raw material medicines in parts by weight: 6 parts of medulla Tetrapanacis and senna; 12 parts of dogbane leaf and one piece of silk; 18 parts of momordica grosvenori and Chinese elderberry; 30 parts of true plates, saururus chinensis and ludwigia prostrata.
Wherein the real dish: sweet and warm. It enters lung and spleen meridians. Tonify qi, strengthen superficies, induce diuresis, expel pus, heal wound and promote tissue regeneration. Can be used for treating chronic nephritis proteinuria. Clinical findings show that true plates significantly reduce mesangial pathological changes. Can promote the renewal of serum and liver proteins, promote protein metabolism, increase serum protein of nephropathy patients, reduce serum cholesterol, and increase blood circulation of glomerular capillary.
Medulla Tetrapanacis: sweet in taste; diluting; cooling; entering the lung; the stomach; the bladder channel. Entering the channels and lungs; clearing heat from stomach channel; diuresis; promoting lactation. The clinical findings are about nephritis; edema; has definite curative effect on dysuria.
Saururus chinensis: sweet, pungent and cold in flavor. It enters lung and bladder meridians. Clear heat and remove toxicity, induce diuresis and alleviate edema. The clinical application shows that the medicine has exact curative effects on difficult urination, dribbling, unsmooth pain, urinary tract infection, nephritis and edema.
And (3) dogbane leaf: sweet, bitter and cool. It enters liver meridian. Pacify liver, tranquilize mind, clear heat and induce diuresis. The clinical findings show that the Chinese medicinal composition has exact curative effect on nephritis edema.
Ludwigia prostrata: sweet in taste; slightly bitter; mild in nature. Invigorating spleen; liver; the bladder channel. Replenishing qi and blood; disperse blood stasis, stop bleeding, clear heat and remove toxicity, induce diuresis to alleviate edema. The clinical findings show that the Chinese medicinal composition has exact curative effects on weakness after diseases, dyspepsia, nephritis and edema.
A piece of silk: slightly sour, slightly bitter and cool. Expelling wind and promoting urination, resolving phlegm and stopping cough, stopping bleeding and activating collaterals, drawing out toxin and promoting granulation. The clinical findings show that the Chinese medicinal preparation has exact curative effect on nephritis edema.
Land English: sweet in taste; slightly bitter; the nature is mild. It enters liver meridian. Soothing liver, strengthening spleen, promoting blood circulation, removing blood stasis, inducing diuresis, and relieving swelling. The clinical findings show that the Chinese medicinal preparation has exact curative effect on nephritis edema. It is forbidden for pregnant women.
Wild hyacinth bean: sweet, slightly bitter and neutral in taste. Clearing away heat and toxic material, invigorating spleen, promoting diuresis, and relieving constipation. The clinical findings show that the Chinese medicinal preparation has exact curative effect on nephritis edema.
Momordica grosvenori: sweet and cool. It enters lung and large intestine meridians. Clear heat and moisten lung, smooth intestine and relax bowels. Clinical application shows that the momordica grosvenori can prevent and treat acute renal failure.
The Chinese medicinal composition for treating chronic nephritis is prepared from Chinese traditional Chinese medicinal herbs, and is prepared by orderly matching certain natural extracts with definite components and clear effects according to a plurality of principles of traditional Chinese medicine treatment based on syndrome differentiation and modern medicine.
The traditional Chinese medicine composition has the effects of promoting blood circulation to remove blood stasis, promoting qi circulation to remove meridian obstruction, can enhance the immune function of organisms, effectively treat chronic nephritis, is safe and reliable, does not have obvious toxic or side effect, does not hurt the spleen and stomach, treats both principal and secondary aspect of disease, and is not easy to relapse.
The traditional Chinese medicine composition has the advantages of small number of medicines, easily obtained raw materials, simple process, low cost and high efficiency, and is beneficial to pharmaceutical enterprises to carry out medicine production and quality control; the product has low price and is easy to be accepted by patients.
The traditional Chinese medicine composition has a remarkable effect on treating chronic nephritis, and clinical experiment results show that the prescription is used for treating chronic nephritis, one dose is taken every day, the decoction is 100 ml and 150ml, the decoction is divided into two parts, one part is taken in the morning and at night, one month is a treatment course, and the chronic nephritis can be cured after 1-4 treatment courses.
The treatment cost of the invention is relatively low and is far lower than that of western medicine.
The invention also provides an oral preparation prepared from the traditional Chinese medicine composition for treating chronic nephritis, the oral preparation comprises oral liquid, tablets, capsules, pills and the like, preferably the dosage forms are tablets and capsules, and one dose is taken every day in the morning and at night.
The traditional Chinese medicine composition can be prepared into various dosage forms. For example, the decocted liquid medicine is sterilized and disinfected and then packaged to prepare oral liquid; or concentrating the decoction, oven drying, adding pharmaceutically acceptable adjuvants, and making into tablet, capsule, pill, etc.
The medically acceptable auxiliary materials comprise starch, dextrin, sodium carboxymethylcellulose, polyethylene glycol, calcium hydrophosphate, sodium alginate, potassium sorbate and the like.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the present invention in any way, and it will be apparent to those skilled in the art that the above description of the present invention can be applied to various modifications, equivalent variations or modifications without departing from the spirit and scope of the present invention.

Claims (4)

1. A traditional Chinese medicine composition for treating chronic nephritis is characterized by comprising the following components: 3-6 parts of medulla Tetrapanacis and senna; 6-12 parts of dogbane leaf and one piece of silk; 9-18 parts of momordica grosvenori and sambucus chinensis; 15-30 parts of true plates, saururus chinensis and ludwigia prostrata.
2. The traditional Chinese medicine for treating chronic nephritis according to claim 1, is characterized by comprising the following raw material medicines in parts by weight: 6 parts of medulla Tetrapanacis and senna; 12 parts of dogbane leaf and one piece of silk; 18 parts of momordica grosvenori and Chinese elderberry; 30 parts of true plates, saururus chinensis and ludwigia prostrata.
3. An oral preparation for treating chronic nephritis, which is prepared from the Chinese medicinal composition of any one of claims 1 or 2.
4. The oral preparation for treating chronic nephritis according to claim 3, which comprises oral liquid, tablets, capsules and pills, preferably capsules and tablets.
CN202010792317.9A 2020-08-09 2020-08-09 Traditional Chinese medicine composition for treating chronic nephritis Withdrawn CN111773283A (en)

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Application Number Priority Date Filing Date Title
CN202010792317.9A CN111773283A (en) 2020-08-09 2020-08-09 Traditional Chinese medicine composition for treating chronic nephritis

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Application Number Priority Date Filing Date Title
CN202010792317.9A CN111773283A (en) 2020-08-09 2020-08-09 Traditional Chinese medicine composition for treating chronic nephritis

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101979058A (en) * 2010-10-22 2011-02-23 石书梅 Chinese medicament for treating chronic nephritis
CN104435828A (en) * 2014-11-19 2015-03-25 商秋伟 Traditional Chinese medicine composition for treating chronic nephritis

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101979058A (en) * 2010-10-22 2011-02-23 石书梅 Chinese medicament for treating chronic nephritis
CN104435828A (en) * 2014-11-19 2015-03-25 商秋伟 Traditional Chinese medicine composition for treating chronic nephritis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
叶定江: "《中药炮制学辞典》", 30 June 2005, 上海科学技术出版社 *

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Application publication date: 20201016

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