CN111773166A - Hydroxyapatite type toothpaste - Google Patents
Hydroxyapatite type toothpaste Download PDFInfo
- Publication number
- CN111773166A CN111773166A CN202010798372.9A CN202010798372A CN111773166A CN 111773166 A CN111773166 A CN 111773166A CN 202010798372 A CN202010798372 A CN 202010798372A CN 111773166 A CN111773166 A CN 111773166A
- Authority
- CN
- China
- Prior art keywords
- parts
- sodium
- fluoride
- hydroxyapatite
- toothpaste
- Prior art date
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- 229910052588 hydroxylapatite Inorganic materials 0.000 title claims abstract description 63
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 title claims abstract description 63
- 239000000606 toothpaste Substances 0.000 title claims abstract description 58
- 229940034610 toothpaste Drugs 0.000 title claims abstract description 57
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 99
- PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical compound [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 claims abstract description 66
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims abstract description 51
- 239000002994 raw material Substances 0.000 claims abstract description 35
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims abstract description 34
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims abstract description 34
- NROKBHXJSPEDAR-UHFFFAOYSA-M potassium fluoride Chemical compound [F-].[K+] NROKBHXJSPEDAR-UHFFFAOYSA-M 0.000 claims abstract description 34
- 239000011775 sodium fluoride Substances 0.000 claims abstract description 33
- 235000013024 sodium fluoride Nutrition 0.000 claims abstract description 33
- 229960002799 stannous fluoride Drugs 0.000 claims abstract description 33
- ANOBYBYXJXCGBS-UHFFFAOYSA-L stannous fluoride Chemical compound F[Sn]F ANOBYBYXJXCGBS-UHFFFAOYSA-L 0.000 claims abstract description 33
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims abstract description 17
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims abstract description 17
- 239000002202 Polyethylene glycol Substances 0.000 claims abstract description 17
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 claims abstract description 17
- 239000011575 calcium Substances 0.000 claims abstract description 17
- 229910052791 calcium Inorganic materials 0.000 claims abstract description 17
- 229910000019 calcium carbonate Inorganic materials 0.000 claims abstract description 17
- JUNWLZAGQLJVLR-UHFFFAOYSA-J calcium diphosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])(=O)OP([O-])([O-])=O JUNWLZAGQLJVLR-UHFFFAOYSA-J 0.000 claims abstract description 17
- 229940043256 calcium pyrophosphate Drugs 0.000 claims abstract description 17
- 235000019821 dicalcium diphosphate Nutrition 0.000 claims abstract description 17
- 229920001223 polyethylene glycol Polymers 0.000 claims abstract description 17
- 239000011698 potassium fluoride Substances 0.000 claims abstract description 17
- 235000003270 potassium fluoride Nutrition 0.000 claims abstract description 17
- 239000000377 silicon dioxide Substances 0.000 claims abstract description 17
- 235000012239 silicon dioxide Nutrition 0.000 claims abstract description 17
- 239000000600 sorbitol Substances 0.000 claims abstract description 17
- 229940074371 monofluorophosphate Drugs 0.000 claims abstract description 10
- BHHYHSUAOQUXJK-UHFFFAOYSA-L zinc fluoride Chemical compound F[Zn]F BHHYHSUAOQUXJK-UHFFFAOYSA-L 0.000 claims description 32
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 claims description 30
- 239000000230 xanthan gum Substances 0.000 claims description 25
- 229920001285 xanthan gum Polymers 0.000 claims description 25
- 235000010493 xanthan gum Nutrition 0.000 claims description 25
- 229940082509 xanthan gum Drugs 0.000 claims description 25
- 239000000049 pigment Substances 0.000 claims description 23
- 238000003756 stirring Methods 0.000 claims description 23
- 238000000227 grinding Methods 0.000 claims description 20
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 17
- 239000011734 sodium Substances 0.000 claims description 17
- 229910052708 sodium Inorganic materials 0.000 claims description 17
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims description 16
- FTLYMKDSHNWQKD-UHFFFAOYSA-N (2,4,5-trichlorophenyl)boronic acid Chemical compound OB(O)C1=CC(Cl)=C(Cl)C=C1Cl FTLYMKDSHNWQKD-UHFFFAOYSA-N 0.000 claims description 16
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 claims description 16
- XGRSAFKZAGGXJV-UHFFFAOYSA-N 3-azaniumyl-3-cyclohexylpropanoate Chemical compound OC(=O)CC(N)C1CCCCC1 XGRSAFKZAGGXJV-UHFFFAOYSA-N 0.000 claims description 16
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims description 16
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims description 16
- 229920002907 Guar gum Polymers 0.000 claims description 16
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims description 16
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims description 16
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims description 16
- 210000003056 antler Anatomy 0.000 claims description 16
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 16
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims description 16
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims description 16
- 239000000679 carrageenan Substances 0.000 claims description 16
- 235000010418 carrageenan Nutrition 0.000 claims description 16
- 229920001525 carrageenan Polymers 0.000 claims description 16
- 229940113118 carrageenan Drugs 0.000 claims description 16
- 229930002875 chlorophyll Natural products 0.000 claims description 16
- 235000019804 chlorophyll Nutrition 0.000 claims description 16
- ATNHDLDRLWWWCB-AENOIHSZSA-M chlorophyll a Chemical compound C1([C@@H](C(=O)OC)C(=O)C2=C3C)=C2N2C3=CC(C(CC)=C3C)=[N+]4C3=CC3=C(C=C)C(C)=C5N3[Mg-2]42[N+]2=C1[C@@H](CCC(=O)OC\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)[C@H](C)C2=C5 ATNHDLDRLWWWCB-AENOIHSZSA-M 0.000 claims description 16
- 239000000665 guar gum Substances 0.000 claims description 16
- 235000010417 guar gum Nutrition 0.000 claims description 16
- 229960002154 guar gum Drugs 0.000 claims description 16
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims description 16
- 229940041616 menthol Drugs 0.000 claims description 16
- 238000000034 method Methods 0.000 claims description 16
- 239000001814 pectin Substances 0.000 claims description 16
- 235000010987 pectin Nutrition 0.000 claims description 16
- 229920001277 pectin Polymers 0.000 claims description 16
- 239000004302 potassium sorbate Substances 0.000 claims description 16
- 235000010241 potassium sorbate Nutrition 0.000 claims description 16
- 229940069338 potassium sorbate Drugs 0.000 claims description 16
- 229940085605 saccharin sodium Drugs 0.000 claims description 16
- 108700004121 sarkosyl Proteins 0.000 claims description 16
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 claims description 16
- 235000010234 sodium benzoate Nutrition 0.000 claims description 16
- 239000004299 sodium benzoate Substances 0.000 claims description 16
- 229940045885 sodium lauroyl sarcosinate Drugs 0.000 claims description 16
- KSAVQLQVUXSOCR-UHFFFAOYSA-M sodium lauroyl sarcosinate Chemical compound [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O KSAVQLQVUXSOCR-UHFFFAOYSA-M 0.000 claims description 16
- 235000019333 sodium laurylsulphate Nutrition 0.000 claims description 16
- 229960004711 sodium monofluorophosphate Drugs 0.000 claims description 16
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims description 16
- 230000008569 process Effects 0.000 claims description 15
- VFLDPWHFBUODDF-FCXRPNKRSA-N curcumin Chemical group C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-FCXRPNKRSA-N 0.000 claims description 14
- UXHAUBHPFCNMCW-UHFFFAOYSA-N cyclohexanamine;sodium Chemical compound [Na].NC1CCCCC1 UXHAUBHPFCNMCW-UHFFFAOYSA-N 0.000 claims description 14
- 239000008213 purified water Substances 0.000 claims description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 14
- 238000002360 preparation method Methods 0.000 claims description 9
- 241001632576 Hyacinthus Species 0.000 claims description 8
- 241000234479 Narcissus Species 0.000 claims description 8
- 244000014047 Polianthes tuberosa Species 0.000 claims description 8
- 235000016067 Polianthes tuberosa Nutrition 0.000 claims description 8
- 239000004148 curcumin Substances 0.000 claims description 7
- 229940109262 curcumin Drugs 0.000 claims description 7
- 235000012754 curcumin Nutrition 0.000 claims description 7
- VFLDPWHFBUODDF-UHFFFAOYSA-N diferuloylmethane Natural products C1=C(O)C(OC)=CC(C=CC(=O)CC(=O)C=CC=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-UHFFFAOYSA-N 0.000 claims description 7
- DWYMPOCYEZONEA-UHFFFAOYSA-N fluorophosphoric acid Chemical compound OP(O)(F)=O DWYMPOCYEZONEA-UHFFFAOYSA-N 0.000 claims description 7
- 238000004806 packaging method and process Methods 0.000 claims description 7
- 241000628997 Flos Species 0.000 claims 7
- 239000002131 composite material Substances 0.000 claims 3
- BPYKTIZUTYGOLE-IFADSCNNSA-N Bilirubin Chemical compound N1C(=O)C(C)=C(C=C)\C1=C\C1=C(C)C(CCC(O)=O)=C(CC2=C(C(C)=C(\C=C/3C(=C(C=C)C(=O)N\3)C)N2)CCC(O)=O)N1 BPYKTIZUTYGOLE-IFADSCNNSA-N 0.000 claims 2
- 238000004140 cleaning Methods 0.000 abstract description 5
- 230000000694 effects Effects 0.000 abstract description 4
- 210000000214 mouth Anatomy 0.000 abstract description 3
- 210000003298 dental enamel Anatomy 0.000 abstract description 2
- 210000004268 dentin Anatomy 0.000 abstract description 2
- 235000019645 odor Nutrition 0.000 abstract 2
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 239000010409 thin film Substances 0.000 abstract 1
- 241000755716 Convallaria Species 0.000 description 7
- 235000009046 Convallaria majalis Nutrition 0.000 description 7
- 244000111489 Gardenia augusta Species 0.000 description 7
- 244000020551 Helianthus annuus Species 0.000 description 7
- 235000003222 Helianthus annuus Nutrition 0.000 description 7
- 241000207840 Jasminum Species 0.000 description 7
- 235000010254 Jasminum officinale Nutrition 0.000 description 7
- 241000218378 Magnolia Species 0.000 description 7
- 241000220317 Rosa Species 0.000 description 7
- 244000223014 Syzygium aromaticum Species 0.000 description 7
- 235000016639 Syzygium aromaticum Nutrition 0.000 description 7
- KFLQGJQSLUYUBF-WOJBJXKFSA-N Phyllanthin Chemical compound C([C@H](COC)[C@@H](COC)CC=1C=C(OC)C(OC)=CC=1)C1=CC=C(OC)C(OC)=C1 KFLQGJQSLUYUBF-WOJBJXKFSA-N 0.000 description 6
- KFLQGJQSLUYUBF-PMACEKPBSA-N Phyllanthin Natural products C([C@@H](COC)[C@H](COC)CC=1C=C(OC)C(OC)=CC=1)C1=CC=C(OC)C(OC)=C1 KFLQGJQSLUYUBF-PMACEKPBSA-N 0.000 description 6
- 230000006872 improvement Effects 0.000 description 6
- 230000002265 prevention Effects 0.000 description 4
- 208000002925 dental caries Diseases 0.000 description 3
- 239000003205 fragrance Substances 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 206010006326 Breath odour Diseases 0.000 description 2
- 208000002064 Dental Plaque Diseases 0.000 description 2
- 208000032139 Halitosis Diseases 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000000796 flavoring agent Substances 0.000 description 2
- 235000019634 flavors Nutrition 0.000 description 2
- UDIPTWFVPPPURJ-UHFFFAOYSA-M Cyclamate Chemical compound [Na+].[O-]S(=O)(=O)NC1CCCCC1 UDIPTWFVPPPURJ-UHFFFAOYSA-M 0.000 description 1
- 241001085205 Prenanthella exigua Species 0.000 description 1
- 239000003082 abrasive agent Substances 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000001680 brushing effect Effects 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 239000000625 cyclamic acid and its Na and Ca salt Substances 0.000 description 1
- 239000000551 dentifrice Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000003670 easy-to-clean Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000002200 mouth mucosa Anatomy 0.000 description 1
- 231100000956 nontoxicity Toxicity 0.000 description 1
- 229960001462 sodium cyclamate Drugs 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses hydroxyapatite type toothpaste, and particularly relates to the field of toothpaste, wherein the hydroxyapatite type toothpaste comprises the following raw materials in parts by weight: 100-120 parts of hydroxyapatite, 80-100 parts of calcium carbonate, 5-9 parts of sodium fluoride, 3-7 parts of potassium fluoride, 1-5 parts of stannous fluoride, 2-6 parts of monofluorophosphate, 1-5 parts of calcium hydrophosphate, 3-7 parts of calcium pyrophosphate, 4-8 parts of silicon dioxide, 4-8 parts of aluminum hydroxide, 5-9 parts of glycerol, 7-11 parts of sorbitol, 7-11 parts of propylene glycol and 6-10 parts of polyethylene glycol. The hydroxyapatite type toothpaste disclosed by the invention has diversified odors, can be purchased according to the favorite odor of a user, increases the applicable population of the product, improves the competitiveness of the product, increases the efficacy of the original foundation, and can remove the thin film and the bacterial plaque on the surface of the tooth without damaging enamel and dentin; has good effect of cleaning oral cavity and periphery.
Description
Technical Field
The invention belongs to the technical field of toothpaste, and particularly relates to hydroxyapatite type toothpaste.
Background
The toothpaste is a cleaning article commonly used in daily life, is a dentifrice, is generally in a gel shape, can be usually smeared on a toothbrush for cleaning teeth, keeps the beauty and brightness of the teeth, has a long history, and with the continuous development of scientific technology, the continuous improvement and perfection of manufacturing technology and equipment, various types of toothpaste are appeared one after another, the quality and the grade of products are continuously improved, and as far as 2019, the variety of the toothpaste is changed from single cleaning type toothpaste, the toothpaste is developed into hundreds of multifunctional toothpastes with complete varieties and various functions, thereby meeting the requirements of different consumption levels.
The hydroxyapatite type toothpaste has the special effects of being healthy and bright white, removing dental plaque, improving gum problems, preventing tooth decay, refreshing breath and the like, but the existing hydroxyapatite type toothpaste has a single formula, so that the toothpaste has single smell, and the smell of the toothpaste cannot be adjusted according to people's liking.
Disclosure of Invention
The invention provides hydroxyapatite type toothpaste, and aims to solve the problems that the existing formula is single, the toothpaste has single smell, and the smell of the toothpaste cannot be adjusted according to the preference of people.
The invention is realized in such a way, and provides the following technical scheme: the hydroxyapatite type toothpaste comprises the following raw materials in parts by weight: 100-120 parts of hydroxyapatite, 80-100 parts of calcium carbonate, 5-9 parts of sodium fluoride, 3-7 parts of potassium fluoride, 1-5 parts of stannous fluoride, 2-6 parts of monofluorophosphate, 1-5 parts of calcium hydrophosphate, 3-7 parts of calcium pyrophosphate, 4-8 parts of silicon dioxide, 4-8 parts of aluminum hydroxide, 5-9 parts of glycerol, 7-11 parts of sorbitol, 7-11 parts of propylene glycol, 6-10 parts of polyethylene glycol, 5-9 parts of sodium lauryl sulfate, 5-9 parts of 2-acyloxy bond sodium sulfonate, 6-10 parts of sodium lauroyl sarcosinate, 7-11 parts of carboxymethyl cellulose, 8-12 parts of antler pectin, 9-13 parts of hydroxyethyl cellulose, 10-14 parts of xanthan gum, 6-10 parts of guar gum, 5-9 parts of carrageenan, 5-9 parts of xanthan gum, 5-9 parts of glycerol, 6-10 parts of sodium cyclohexylamine sulfonate, 3-7 parts of saccharin sodium, 3-7 parts of potassium sorbate, 3-7 parts of sodium benzoate, 2-6 parts of menthol, 2-6 parts of pigment, 3-7 parts of essence, 7-11 parts of chlorophyll, 5-9 parts of sodium fluoride, 5-9 parts of stannous fluoride, 4-8 parts of sodium monofluorophosphate and 2-6 parts of zinc fluoride.
In a preferred embodiment, the composition comprises the following raw materials in parts by weight: 105-115 parts of hydroxyapatite, 85-9 parts of calcium carbonate, 5 parts of sodium fluoride, 6-8 parts of potassium fluoride, 2-4 parts of stannous fluoride, 3-5 parts of monofluorophosphate, 2-4 parts of calcium hydrophosphate, 4-6 parts of calcium pyrophosphate, 5-7 parts of silicon dioxide, 5-7 parts of aluminum hydroxide, 6-8 parts of glycerol, 8-10 parts of sorbitol, 8-10 parts of propylene glycol, 7-9 parts of polyethylene glycol, 6-8 parts of sodium lauryl sulfate, 6-8 parts of 2-acyloxy bond sodium sulfonate, 7-9 parts of sodium lauroyl sarcosinate, 8-10 parts of carboxymethyl cellulose, 9-11 parts of antler pectin, 10-12 parts of hydroxyethyl cellulose, 11-13 parts of xanthan gum, 7-9 parts of guar gum, 6-8 parts of carrageenan, 6-8 parts of xanthan gum, 6-8 parts of glycerol, 7-9 parts of sodium cyclohexylamine sulfonate, 4-6 parts of saccharin sodium, 4-6 parts of potassium sorbate and sodium benzoate, 3-5 parts of menthol, 3-5 parts of pigment, 4-6 parts of essence, 8-10 parts of chlorophyll, 6-8 parts of sodium fluoride, 6-8 parts of stannous fluoride, 5-7 parts of sodium monofluorophosphate and 3-5 parts of zinc fluoride.
In a preferred embodiment, the composition comprises the following raw materials in parts by weight: 110 parts of hydroxyapatite, 90 parts of calcium carbonate, 7 parts of sodium fluoride, 5 parts of potassium fluoride, 3 parts of stannous fluoride, 4 parts of monofluorophosphoric acid, 3 parts of calcium hydrophosphate, 5 parts of calcium pyrophosphate, 6 parts of silicon dioxide, 6 parts of aluminum hydroxide, 7 parts of glycerol, 9 parts of sorbitol, 9 parts of propylene glycol, 8 parts of polyethylene glycol, 7 parts of sodium lauryl sulfate, 7 parts of sodium 2-acyloxy bond sulfonate, 8 parts of sodium lauroyl sarcosinate, 9 parts of carboxymethyl cellulose, 10 parts of antler pectin, 11 parts of hydroxyethyl cellulose, 12 parts of xanthan gum, 8 parts of guar gum, 7 parts of carrageenan, 7 parts of glycerol, 8 parts of sodium cyclohexylamine sulfonate, 5 parts of saccharin sodium, 5 parts of potassium sorbate and sodium benzoate, 4 parts of menthol, 4 parts of pigment, 5 parts of essence, 9 parts of chlorophyll, 7 parts of sodium fluoride, 7 parts of stannous fluoride, 6 parts of sodium monofluorophosphate and 4 parts of zinc fluoride.
In a preferred embodiment, the method further comprises a preparation process of the hydroxyapatite type toothpaste, and the preparation process specifically comprises the following steps:
step one, grinding all the raw materials in a grinder for 4 hours at the temperature of 2-6 ℃, and adding purified water in the grinding process.
And step two, putting the raw materials ground in the step one into a stirrer for stirring, controlling the temperature at 2-6 ℃, stirring for 6 hours, adding purified water in the stirring process until all the raw materials are uniformly stirred, and thus obtaining the hydroxyapatite type toothpaste.
And step three, bottling and packaging the hydroxyapatite toothpaste obtained in the step two.
In a preferred embodiment, the pigments are curcumin and phyllanthin.
In a preferred embodiment, the essence is one or more of rose, jasmine, tuberose, lily of the valley, magnolia, clove, narcissus, sunflower, orange blossom, gardenia and hyacinth.
Compared with the prior art, the invention has the beneficial effects that:
1. by adding the essence, the essence can be one or a combination of more of rose, jasmine, tuberose, lily of the valley, magnolia, clove, narcissus, sunflower, orange blossom, gardenia and hyacinth, so as to achieve different fragrances, so that people can purchase the fragrance required by themselves according to their liking, thereby increasing the applicable population of the product and improving the competitiveness of the product;
2. by adding various abrasives, adhesives, purifiers and wetting agents into the formula, the hydroxyapatite toothpaste has more effects, the original basic effects are improved, and films and dental plaques on the surfaces of teeth can be removed without damaging enamel and dentin; has good function of cleaning the oral cavity and the periphery thereof; no toxicity and no stimulation to oral mucosa; has comfortable fragrance and taste, and has cool and fresh feeling after use; easy to use, and is extruded into uniform, bright and soft strips; the tooth brush is easy to clean from the oral cavity, teeth and toothbrushes, has good chemical and physical stability, and ensures that all indexes meet the standard requirements in the storage period; has reasonable cost performance.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
Example 1:
the hydroxyapatite type toothpaste comprises the following raw materials in parts by weight: 100-120 parts of hydroxyapatite, 80-100 parts of calcium carbonate, 5-9 parts of sodium fluoride, 3-7 parts of potassium fluoride, 1-5 parts of stannous fluoride, 2-6 parts of monofluorophosphate, 1-5 parts of calcium hydrophosphate, 3-7 parts of calcium pyrophosphate, 4-8 parts of silicon dioxide, 4-8 parts of aluminum hydroxide, 5-9 parts of glycerol, 7-11 parts of sorbitol, 7-11 parts of propylene glycol, 6-10 parts of polyethylene glycol, 5-9 parts of sodium lauryl sulfate, 5-9 parts of 2-acyloxy bond sodium sulfonate, 6-10 parts of sodium lauroyl sarcosinate, 7-11 parts of carboxymethyl cellulose, 8-12 parts of antler pectin, 9-13 parts of hydroxyethyl cellulose, 10-14 parts of xanthan gum, 6-10 parts of guar gum, 5-9 parts of carrageenan, 5-9 parts of xanthan gum, 5-9 parts of glycerol, 6-10 parts of sodium cyclohexylamine sulfonate, 3-7 parts of saccharin sodium, 3-7 parts of potassium sorbate, 3-7 parts of sodium benzoate, 2-6 parts of menthol, 2-6 parts of pigment, 3-7 parts of essence, 7-11 parts of chlorophyll, 5-9 parts of sodium fluoride, 5-9 parts of stannous fluoride, 4-8 parts of sodium monofluorophosphate and 2-6 parts of zinc fluoride;
specifically, in this embodiment, the following steps are specifically performed: 100 parts of hydroxyapatite, 80 parts of calcium carbonate, 5 parts of sodium fluoride, 3 parts of potassium fluoride, 1 part of stannous fluoride, 2 parts of monofluorophosphoric acid, 1 part of calcium hydrophosphate, 3 parts of calcium pyrophosphate, 4 parts of silicon dioxide, 4 parts of aluminum hydroxide, 5 parts of glycerol, 7 parts of sorbitol, 7 parts of propylene glycol, 6 parts of polyethylene glycol, 5 parts of sodium lauryl sulfate, 5 parts of 2-acyloxy bond sodium sulfonate, 6 parts of sodium lauroyl sarcosinate, 7 parts of carboxymethyl cellulose, 8 parts of antler pectin, 9 parts of hydroxyethyl cellulose, 10 parts of xanthan gum, 6 parts of guar gum, 5 parts of carrageenan, 5 parts of glycerol, 6 parts of sodium cyclamate, 3 parts of saccharin sodium, 3 parts of potassium sorbate and sodium benzoate, 2 parts of menthol, 2 parts of pigment, 3 parts of essence, 7 parts of chlorophyll, 5 parts of sodium fluoride, 5 parts of stannous fluoride, 4 parts of sodium monofluorophosphate and 2 parts of zinc fluoride;
the preparation process of the hydroxyapatite type toothpaste specifically comprises the following steps:
step one, grinding all the raw materials in a grinder at the temperature of 2 ℃ for 4h, and adding purified water in the grinding process;
step two, putting the ground raw materials in the step one into a stirrer for stirring, controlling the temperature at 2 ℃, stirring for 6 hours, adding purified water in the stirring process until all the raw materials are uniformly stirred, and preparing the hydroxyapatite toothpaste;
and step three, bottling and packaging the hydroxyapatite toothpaste obtained in the step two.
In the above embodiment, the pigment is curcumin and phyllanthin, and the essence is one or more of rose, jasmine, tuberose, lily of the valley, magnolia, clove, narcissus, sunflower, orange blossom, gardenia and hyacinth.
Example 2:
the hydroxyapatite type toothpaste comprises the following raw materials in parts by weight: 100-120 parts of hydroxyapatite, 80-100 parts of calcium carbonate, 5-9 parts of sodium fluoride, 3-7 parts of potassium fluoride, 1-5 parts of stannous fluoride, 2-6 parts of monofluorophosphate, 1-5 parts of calcium hydrophosphate, 3-7 parts of calcium pyrophosphate, 4-8 parts of silicon dioxide, 4-8 parts of aluminum hydroxide, 5-9 parts of glycerol, 7-11 parts of sorbitol, 7-11 parts of propylene glycol, 6-10 parts of polyethylene glycol, 5-9 parts of sodium lauryl sulfate, 5-9 parts of 2-acyloxy bond sodium sulfonate, 6-10 parts of sodium lauroyl sarcosinate, 7-11 parts of carboxymethyl cellulose, 8-12 parts of antler pectin, 9-13 parts of hydroxyethyl cellulose, 10-14 parts of xanthan gum, 6-10 parts of guar gum, 5-9 parts of carrageenan, 5-9 parts of xanthan gum, 5-9 parts of glycerol, 6-10 parts of sodium cyclohexylamine sulfonate, 3-7 parts of saccharin sodium, 3-7 parts of potassium sorbate, 3-7 parts of sodium benzoate, 2-6 parts of menthol, 2-6 parts of pigment, 3-7 parts of essence, 7-11 parts of chlorophyll, 5-9 parts of sodium fluoride, 5-9 parts of stannous fluoride, 4-8 parts of sodium monofluorophosphate and 2-6 parts of zinc fluoride;
specifically, in this embodiment, the following steps are specifically performed: 105 parts of hydroxyapatite, 85 parts of calcium carbonate, 6 parts of sodium fluoride, 4 parts of potassium fluoride, 2 parts of stannous fluoride, 3 parts of monofluorophosphoric acid, 2 parts of calcium hydrophosphate, 4 parts of calcium pyrophosphate, 5 parts of silicon dioxide, 5 parts of aluminum hydroxide, 6 parts of glycerol, 8 parts of sorbitol, 8 parts of propylene glycol, 7 parts of polyethylene glycol, 6 parts of sodium lauryl sulfate, 6 parts of 2-acyloxy bond sodium sulfonate, 7 parts of sodium lauroyl sarcosinate, 8 parts of carboxymethyl cellulose, 9 parts of antler pectin, 10 parts of hydroxyethyl cellulose, 11 parts of xanthan gum, 7 parts of guar gum, 6 parts of carrageenan, 6 parts of glycerol, 7 parts of sodium cyclohexylamine sulfonate, 4 parts of saccharin sodium, 4 parts of potassium sorbate and sodium benzoate, 3 parts of menthol, 3 parts of pigment, 4 parts of essence, 8 parts of chlorophyll, 6 parts of sodium fluoride, 6 parts of stannous fluoride, 5 parts of sodium monofluorophosphate and 3 parts of zinc fluoride;
the preparation process of the hydroxyapatite type toothpaste specifically comprises the following steps:
step one, grinding all the raw materials in a grinding machine at the temperature of 3 ℃ for 4h, and adding purified water in the grinding process;
step two, putting the ground raw materials in the step one into a stirrer for stirring, controlling the temperature at 3 ℃, stirring for 6 hours, adding purified water in the stirring process until all the raw materials are uniformly stirred, and preparing the hydroxyapatite toothpaste;
and step three, bottling and packaging the hydroxyapatite toothpaste obtained in the step two.
In the above embodiment, the pigment is curcumin and phyllanthin, and the essence is one or more of rose, jasmine, tuberose, lily of the valley, magnolia, clove, narcissus, sunflower, orange blossom, gardenia and hyacinth.
Example 3:
the hydroxyapatite type toothpaste comprises the following raw materials in parts by weight: 100-120 parts of hydroxyapatite, 80-100 parts of calcium carbonate, 5-9 parts of sodium fluoride, 3-7 parts of potassium fluoride, 1-5 parts of stannous fluoride, 2-6 parts of monofluorophosphate, 1-5 parts of calcium hydrophosphate, 3-7 parts of calcium pyrophosphate, 4-8 parts of silicon dioxide, 4-8 parts of aluminum hydroxide, 5-9 parts of glycerol, 7-11 parts of sorbitol, 7-11 parts of propylene glycol, 6-10 parts of polyethylene glycol, 5-9 parts of sodium lauryl sulfate, 5-9 parts of 2-acyloxy bond sodium sulfonate, 6-10 parts of sodium lauroyl sarcosinate, 7-11 parts of carboxymethyl cellulose, 8-12 parts of antler pectin, 9-13 parts of hydroxyethyl cellulose, 10-14 parts of xanthan gum, 6-10 parts of guar gum, 5-9 parts of carrageenan, 5-9 parts of xanthan gum, 5-9 parts of glycerol, 6-10 parts of sodium cyclohexylamine sulfonate, 3-7 parts of saccharin sodium, 3-7 parts of potassium sorbate, 3-7 parts of sodium benzoate, 2-6 parts of menthol, 2-6 parts of pigment, 3-7 parts of essence, 7-11 parts of chlorophyll, 5-9 parts of sodium fluoride, 5-9 parts of stannous fluoride, 4-8 parts of sodium monofluorophosphate and 2-6 parts of zinc fluoride;
specifically, in this embodiment, the following steps are specifically performed: 110 parts of hydroxyapatite, 90 parts of calcium carbonate, 7 parts of sodium fluoride, 5 parts of potassium fluoride, 3 parts of stannous fluoride, 4 parts of monofluorophosphoric acid, 3 parts of calcium hydrophosphate, 5 parts of calcium pyrophosphate, 6 parts of silicon dioxide, 6 parts of aluminum hydroxide, 7 parts of glycerol, 9 parts of sorbitol, 9 parts of propylene glycol, 8 parts of polyethylene glycol, 7 parts of sodium lauryl sulfate, 7 parts of sodium 2-acyloxy bond sulfonate, 8 parts of sodium lauroyl sarcosinate, 9 parts of carboxymethyl cellulose, 10 parts of antler pectin, 11 parts of hydroxyethyl cellulose, 12 parts of xanthan gum, 8 parts of guar gum, 7 parts of carrageenan, 7 parts of glycerol, 8 parts of sodium cyclohexylamine sulfonate, 5 parts of saccharin sodium, 5 parts of potassium sorbate and sodium benzoate, 4 parts of menthol, 4 parts of pigment, 5 parts of essence, 9 parts of chlorophyll, 7 parts of sodium fluoride, 7 parts of stannous fluoride, 6 parts of sodium monofluorophosphate and 4 parts of zinc fluoride;
the preparation process of the hydroxyapatite type toothpaste specifically comprises the following steps:
step one, grinding all the raw materials in a grinding machine at the temperature of 4 ℃ for 4h, and adding purified water in the grinding process;
step two, putting the ground raw materials in the step one into a stirrer for stirring, controlling the temperature at 4 ℃, stirring for 6 hours, adding purified water in the stirring process until all the raw materials are uniformly stirred, and preparing the hydroxyapatite toothpaste;
and step three, bottling and packaging the hydroxyapatite toothpaste obtained in the step two.
In the above embodiment, the pigment is curcumin and phyllanthin, and the essence is one or more of rose, jasmine, tuberose, lily of the valley, magnolia, clove, narcissus, sunflower, orange blossom, gardenia and hyacinth.
Example 4:
the hydroxyapatite type toothpaste comprises the following raw materials in parts by weight: 100-120 parts of hydroxyapatite, 80-100 parts of calcium carbonate, 5-9 parts of sodium fluoride, 3-7 parts of potassium fluoride, 1-5 parts of stannous fluoride, 2-6 parts of monofluorophosphate, 1-5 parts of calcium hydrophosphate, 3-7 parts of calcium pyrophosphate, 4-8 parts of silicon dioxide, 4-8 parts of aluminum hydroxide, 5-9 parts of glycerol, 7-11 parts of sorbitol, 7-11 parts of propylene glycol, 6-10 parts of polyethylene glycol, 5-9 parts of sodium lauryl sulfate, 5-9 parts of 2-acyloxy bond sodium sulfonate, 6-10 parts of sodium lauroyl sarcosinate, 7-11 parts of carboxymethyl cellulose, 8-12 parts of antler pectin, 9-13 parts of hydroxyethyl cellulose, 10-14 parts of xanthan gum, 6-10 parts of guar gum, 5-9 parts of carrageenan, 5-9 parts of xanthan gum, 5-9 parts of glycerol, 6-10 parts of sodium cyclohexylamine sulfonate, 3-7 parts of saccharin sodium, 3-7 parts of potassium sorbate, 3-7 parts of sodium benzoate, 2-6 parts of menthol, 2-6 parts of pigment, 3-7 parts of essence, 7-11 parts of chlorophyll, 5-9 parts of sodium fluoride, 5-9 parts of stannous fluoride, 4-8 parts of sodium monofluorophosphate and 2-6 parts of zinc fluoride;
specifically, in this embodiment, the following steps are specifically performed: 115 parts of hydroxyapatite, 95 parts of calcium carbonate, 8 parts of sodium fluoride, 6 parts of potassium fluoride, 4 parts of stannous fluoride, 5 parts of monofluorophosphoric acid, 4 parts of calcium hydrophosphate, 6 parts of calcium pyrophosphate, 7 parts of silicon dioxide, 7 parts of aluminum hydroxide, 8 parts of glycerol, 10 parts of sorbitol, 10 parts of propylene glycol, 9 parts of polyethylene glycol, 8 parts of sodium lauryl sulfate, 8 parts of 2-acyloxy bond sodium sulfonate, 9 parts of sodium lauroyl sarcosinate, 10 parts of carboxymethyl cellulose, 8-12 parts of antler pectin, 12 parts of hydroxyethyl cellulose, 13 parts of xanthan gum, 9 parts of guar gum, 8 parts of carrageenan, 8 parts of glycerol, 6-10 parts of sodium cyclohexylamine sulfonate, 3-7 parts of saccharin sodium, 6 parts of potassium sorbate and sodium benzoate, 5 parts of menthol, 5 parts of pigment, 6 parts of essence, 10 parts of chlorophyll, 8 parts of sodium fluoride, 8 parts of stannous fluoride, 4-8 parts of sodium monofluorophosphate, 8 parts of sodium, 5 parts of zinc fluoride;
the preparation process of the hydroxyapatite type toothpaste specifically comprises the following steps:
step one, grinding all the raw materials in a grinder for 4 hours at the temperature of 5 ℃, and adding purified water in the grinding process;
step two, putting the ground raw materials in the step one into a stirrer for stirring, controlling the temperature at 5 ℃, stirring for 6 hours, adding purified water in the stirring process until all the raw materials are uniformly stirred, and preparing the hydroxyapatite toothpaste;
and step three, bottling and packaging the hydroxyapatite toothpaste obtained in the step two.
In the above embodiment, the pigment is curcumin and phyllanthin, and the essence is one or more of rose, jasmine, tuberose, lily of the valley, magnolia, clove, narcissus, sunflower, orange blossom, gardenia and hyacinth.
Example 5:
the hydroxyapatite type toothpaste comprises the following raw materials in parts by weight: 100-120 parts of hydroxyapatite, 80-100 parts of calcium carbonate, 5-9 parts of sodium fluoride, 3-7 parts of potassium fluoride, 1-5 parts of stannous fluoride, 2-6 parts of monofluorophosphate, 1-5 parts of calcium hydrophosphate, 3-7 parts of calcium pyrophosphate, 4-8 parts of silicon dioxide, 4-8 parts of aluminum hydroxide, 5-9 parts of glycerol, 7-11 parts of sorbitol, 7-11 parts of propylene glycol, 6-10 parts of polyethylene glycol, 5-9 parts of sodium lauryl sulfate, 5-9 parts of 2-acyloxy bond sodium sulfonate, 6-10 parts of sodium lauroyl sarcosinate, 7-11 parts of carboxymethyl cellulose, 8-12 parts of antler pectin, 9-13 parts of hydroxyethyl cellulose, 10-14 parts of xanthan gum, 6-10 parts of guar gum, 5-9 parts of carrageenan, 5-9 parts of xanthan gum, 5-9 parts of glycerol, 6-10 parts of sodium cyclohexylamine sulfonate, 3-7 parts of saccharin sodium, 3-7 parts of potassium sorbate, 3-7 parts of sodium benzoate, 2-6 parts of menthol, 2-6 parts of pigment, 3-7 parts of essence, 7-11 parts of chlorophyll, 5-9 parts of sodium fluoride, 5-9 parts of stannous fluoride, 4-8 parts of sodium monofluorophosphate and 2-6 parts of zinc fluoride;
specifically, in this embodiment, the following steps are specifically performed: 120 parts of hydroxyapatite, 100 parts of calcium carbonate, 9 parts of sodium fluoride, 7 parts of potassium fluoride, 5 parts of stannous fluoride, 6 parts of monofluorophosphoric acid, 5 parts of calcium hydrophosphate, 7 parts of calcium pyrophosphate, 8 parts of silicon dioxide, 8 parts of aluminum hydroxide, 9 parts of glycerol, 11 parts of sorbitol, 11 parts of propylene glycol, 10 parts of polyethylene glycol, 9 parts of sodium lauryl sulfate, 9 parts of sodium 2-acyloxy bond sulfonate, 10 parts of sodium lauroyl sarcosinate, 11 parts of carboxymethyl cellulose, 12 parts of antler pectin, 13 parts of hydroxyethyl cellulose, 14 parts of xanthan gum, 10 parts of guar gum, 9 parts of carrageenan, 9 parts of glycerol, 10 parts of sodium cyclohexylamine sulfonate, 7 parts of saccharin sodium, 7 parts of potassium sorbate and sodium benzoate, 6 parts of menthol, 6 parts of pigment, 7 parts of essence, 11 parts of chlorophyll, 9 parts of sodium fluoride, 9 parts of stannous fluoride, 8 parts of sodium monofluorophosphate and 6 parts of zinc fluoride;
the preparation process of the hydroxyapatite type toothpaste specifically comprises the following steps:
step one, grinding all the raw materials in a grinding machine at the temperature of 6 ℃ for 4h, and adding purified water in the grinding process;
step two, putting the ground raw materials in the step one into a stirrer for stirring, controlling the temperature at 6 ℃, stirring for 6 hours, adding purified water in the stirring process until all the raw materials are uniformly stirred, and preparing the hydroxyapatite toothpaste;
and step three, bottling and packaging the hydroxyapatite toothpaste obtained in the step two.
In the above embodiment, the pigment is curcumin and phyllanthin, and the essence is one or more of rose, jasmine, tuberose, lily of the valley, magnolia, clove, narcissus, sunflower, orange blossom, gardenia and hyacinth.
The hydroxyapatite type toothpaste prepared in the above examples 1 to 5 was respectively taken, the grinding temperature and the stirring temperature were changed by changing the ratio of the raw materials, and then the flavor enhancement rate, the tooth-decay prevention enhancement rate and the halitosis prevention enhancement rate of the hydroxyapatite type toothpaste prepared in the above examples 1 to 5 were tested by the related experiments, and then the following data were obtained by statistics and calculation:
as can be seen from the above table, in example 3, the mixture ratio of the raw materials, the grinding temperature and the stirring temperature during preparation are moderate, and after relevant experimental tests, the hydroxyapatite type toothpaste prepared in example 3 has the highest flavor improvement rate, the highest tooth brushing whitening effect improvement rate, the highest tooth decay prevention improvement rate and the highest halitosis prevention improvement rate.
The present invention is not limited to the above preferred embodiments, and any modifications, equivalent substitutions and improvements made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (6)
1. A hydroxyapatite type toothpaste characterized in that: the composite material comprises the following raw materials in parts by weight: 100-120 parts of hydroxyapatite, 80-100 parts of calcium carbonate, 5-9 parts of sodium fluoride, 3-7 parts of potassium fluoride, 1-5 parts of stannous fluoride, 2-6 parts of monofluorophosphate, 1-5 parts of calcium hydrophosphate, 3-7 parts of calcium pyrophosphate, 4-8 parts of silicon dioxide, 4-8 parts of aluminum hydroxide, 5-9 parts of glycerol, 7-11 parts of sorbitol, 7-11 parts of propylene glycol, 6-10 parts of polyethylene glycol, 5-9 parts of sodium lauryl sulfate, 5-9 parts of 2-acyloxy bond sodium sulfonate, 6-10 parts of sodium lauroyl sarcosinate, 7-11 parts of carboxymethyl cellulose, 8-12 parts of antler pectin, 9-13 parts of hydroxyethyl cellulose, 10-14 parts of xanthan gum, 6-10 parts of guar gum, 5-9 parts of carrageenan, 5-9 parts of xanthan gum, 5-9 parts of glycerol, 6-10 parts of sodium cyclohexylamine sulfonate, 3-7 parts of saccharin sodium, 3-7 parts of potassium sorbate, 3-7 parts of sodium benzoate, 2-6 parts of menthol, 2-6 parts of pigment, 3-7 parts of essence, 7-11 parts of chlorophyll, 5-9 parts of sodium fluoride, 5-9 parts of stannous fluoride, 4-8 parts of sodium monofluorophosphate and 2-6 parts of zinc fluoride.
2. A hydroxyapatite toothpaste according to claim 1 wherein: the composite material comprises the following raw materials in parts by weight: 105-115 parts of hydroxyapatite, 85-9 parts of calcium carbonate, 5 parts of sodium fluoride, 6-8 parts of potassium fluoride, 2-4 parts of stannous fluoride, 3-5 parts of monofluorophosphate, 2-4 parts of calcium hydrophosphate, 4-6 parts of calcium pyrophosphate, 5-7 parts of silicon dioxide, 5-7 parts of aluminum hydroxide, 6-8 parts of glycerol, 8-10 parts of sorbitol, 8-10 parts of propylene glycol, 7-9 parts of polyethylene glycol, 6-8 parts of sodium lauryl sulfate, 6-8 parts of 2-acyloxy bond sodium sulfonate, 7-9 parts of sodium lauroyl sarcosinate, 8-10 parts of carboxymethyl cellulose, 9-11 parts of antler pectin, 10-12 parts of hydroxyethyl cellulose, 11-13 parts of xanthan gum, 7-9 parts of guar gum, 6-8 parts of carrageenan, 6-8 parts of xanthan gum, 6-8 parts of glycerol, 7-9 parts of sodium cyclohexylamine sulfonate, 4-6 parts of saccharin sodium, 4-6 parts of potassium sorbate and sodium benzoate, 3-5 parts of menthol, 3-5 parts of pigment, 4-6 parts of essence, 8-10 parts of chlorophyll, 6-8 parts of sodium fluoride, 6-8 parts of stannous fluoride, 5-7 parts of sodium monofluorophosphate and 3-5 parts of zinc fluoride.
3. A hydroxyapatite toothpaste according to claim 1 wherein: the composite material comprises the following raw materials in parts by weight: 110 parts of hydroxyapatite, 90 parts of calcium carbonate, 7 parts of sodium fluoride, 5 parts of potassium fluoride, 3 parts of stannous fluoride, 4 parts of monofluorophosphoric acid, 3 parts of calcium hydrophosphate, 5 parts of calcium pyrophosphate, 6 parts of silicon dioxide, 6 parts of aluminum hydroxide, 7 parts of glycerol, 9 parts of sorbitol, 9 parts of propylene glycol, 8 parts of polyethylene glycol, 7 parts of sodium lauryl sulfate, 7 parts of sodium 2-acyloxy bond sulfonate, 8 parts of sodium lauroyl sarcosinate, 9 parts of carboxymethyl cellulose, 10 parts of antler pectin, 11 parts of hydroxyethyl cellulose, 12 parts of xanthan gum, 8 parts of guar gum, 7 parts of carrageenan, 7 parts of glycerol, 8 parts of sodium cyclohexylamine sulfonate, 5 parts of saccharin sodium, 5 parts of potassium sorbate and sodium benzoate, 4 parts of menthol, 4 parts of pigment, 5 parts of essence, 9 parts of chlorophyll, 7 parts of sodium fluoride, 7 parts of stannous fluoride, 6 parts of sodium monofluorophosphate and 4 parts of zinc fluoride.
4. A hydroxyapatite toothpaste according to any one of claims 1 to 3 further comprising a process for the preparation of a hydroxyapatite toothpaste, in particular comprising the following steps:
step one, grinding all the raw materials in a grinding machine at the temperature of 2-6 ℃ for 4h, and adding purified water in the grinding process;
step two, putting the ground raw materials in the step one into a stirrer for stirring, controlling the temperature at 2-6 ℃, stirring for 6 hours, adding purified water in the stirring process until all the raw materials are uniformly stirred, and preparing the hydroxyapatite toothpaste;
and step three, bottling and packaging the hydroxyapatite toothpaste obtained in the step two.
5. A hydroxyapatite toothpaste according to claim 1 wherein: the pigment is curcumin and bilirubin.
6. A hydroxyapatite toothpaste according to claim 1 wherein: the essence is one or more of flos Rosae Rugosae, flos Jasmini sambac, tuberose, flos Convallariae, flos Magnoliae, flos Caryophylli, Narcissus chinensis, flos Helianthi, flos Citri Junoris, fructus Gardeniae, and hyacinth.
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| KR20000007808A (en) * | 1998-07-07 | 2000-02-07 | 성재갑 | Whitening toothpaste composition |
| CN103417397A (en) * | 2013-08-13 | 2013-12-04 | 上海方木精细化工有限公司 | Hydroxyapatite type toothpaste |
| CN105640788A (en) * | 2016-01-27 | 2016-06-08 | 杭州皎洁口腔保健用品有限公司 | Hydroxyapatite toothpaste and preparation method thereof |
| CN108272646A (en) * | 2018-04-11 | 2018-07-13 | 佳木斯大学 | A kind of antibacterial toothpaste and preparation method thereof of hydroxyl apatite |
-
2020
- 2020-08-10 CN CN202010798372.9A patent/CN111773166A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20000007808A (en) * | 1998-07-07 | 2000-02-07 | 성재갑 | Whitening toothpaste composition |
| CN103417397A (en) * | 2013-08-13 | 2013-12-04 | 上海方木精细化工有限公司 | Hydroxyapatite type toothpaste |
| CN105640788A (en) * | 2016-01-27 | 2016-06-08 | 杭州皎洁口腔保健用品有限公司 | Hydroxyapatite toothpaste and preparation method thereof |
| CN108272646A (en) * | 2018-04-11 | 2018-07-13 | 佳木斯大学 | A kind of antibacterial toothpaste and preparation method thereof of hydroxyl apatite |
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