CN111773143B - Anti-aging firming mask liquid and preparation method thereof - Google Patents

Abstract

The invention discloses an anti-aging firming mask liquid and a preparation method thereof, and belongs to the technical field of daily cosmetics. The anti-aging firming mask liquid comprises the following components in parts by weight: 0.0000003-0.00003 part of fullerene, 0.01-2 parts of stevioside and 0.01-3 parts of brown algae extract. The facial mask liquid prepared by the formula disclosed by the invention has excellent moisturizing performance, and can repair skin, fade fine wrinkles and enable the skin to be firmer. In addition, the mask liquid can be prepared by simply mixing the materials, and the preparation method is simple and suitable for industrial production.

Description

Anti-aging firming mask liquid and preparation method thereof

Technical Field

The invention belongs to the technical field of daily cosmetics, and particularly relates to anti-aging firming mask liquid and a preparation method thereof.

Background

With the age, the metabolism speed of the human body is reduced, the renewal speed of skin cells is correspondingly reduced, the synthesis of collagen is reduced, the elasticity is weakened, and the phenomena of wrinkles and facial cuticles appear. In addition, environmental pollution, ultraviolet radiation, etc. cause the skin to generate free radicals continuously, resulting in the skin being oxidized too fast, dull and lusterless. At the same time, irregular daily work and rest can also affect the normal metabolism of skin cells. In addition, the skin care products on the market are all five-door, the quality of the products is good, and consumers often select improper products to further damage the skin.

Disclosure of Invention

The invention aims to overcome the defects of the prior art and provide anti-aging firming mask liquid which is safe and harmless to skin and a preparation method thereof.

In order to achieve the purpose, the technical scheme adopted by the invention is as follows: an anti-aging firming facial mask liquid comprises fullerene, stevioside and brown algae extract.

The fullerene can be compatible with free radicals, has super-strong and high-persistence oxidation resistance, activates skin cells, and has a good effect of preventing skin aging. The stevioside has skin caring, skin whitening, and antiinflammatory effects. The brown algae extract has melanin formation inhibiting, antioxidant, and antiinflammatory effects.

Preferably, the anti-aging firming mask liquid comprises the following components in parts by weight: 0.0000003-0.00003 part of fullerene, 0.01-2 parts of stevioside and 0.01-3 parts of brown algae extract.

Preferably, the anti-aging firming mask liquid comprises the following components in parts by weight: 0.00001 part of fullerene, 0.5 part of stevioside and 1 part of brown algae extract.

Preferably, the anti-aging firming mask liquid further comprises a lubricant, a humectant, a film forming agent, a thickening agent, a solubilizer and a preservative.

Preferably, the lubricant in the anti-aging firming mask fluid comprises glycerol; the humectant comprises propylene glycol, butylene glycol, trehalose, sodium hyaluronate and ethylhexylglycerin; the film forming agent comprises polyvinylpyrrolidone and hydroxyethyl cellulose; the thickener comprises xanthan gum and polyethylene glycol-115M; the solubilizer comprises PEG-40 hydrogenated castor oil; the preservative comprises methylparaben, p-hydroxyacetophenone and phenoxyethanol.

Preferably, the anti-aging firming mask solution comprises a phase A, a phase B, a phase C, a phase D and a phase E, wherein the phase A comprises glycerin, xanthan gum, trehalose, sodium hyaluronate, hydroxyethyl cellulose, methylparaben, p-hydroxyacetophenone and water; the phase B comprises phenoxyethanol and ethylhexyl glycerol; the C phase comprises essence and PEG-40 hydrogenated castor oil; the phase D comprises 0.5-3 parts of propylene glycol and polyethylene glycol-115M; the E phase comprises butanediol, polyvinylpyrrolidone, fullerene, stevioside, brown algae extract and water.

Preferably, the anti-aging firming mask liquid comprises the following components in parts by weight: 2-6 parts of glycerol, 0.05-0.3 part of xanthan gum, 0.5-3 parts of trehalose, 0.005-0.04 part of sodium hyaluronate, 0.005-0.05 part of hydroxyethyl cellulose, 0.005-0.15 part of methyl hydroxybenzoate, 0.05-0.6 part of p-hydroxyacetophenone, 0.0045-0.63 part of phenoxyethanol, 0.0005-0.07 part of ethylhexyl glycerol, 0.0005-0.1 part of essence, 0.002-0.4 part of PEG-40 hydrogenated castor oil, 0.5-3 parts of propylene glycol, 0.001-0.1 part of polyethylene glycol-115M, 0.00075-0.075 part of butanediol, 0.0001-0.01 part of polyvinylpyrrolidone, 0.0000003-0.00003 part of fullerene, 0.01-2 parts of stevioside, 0.01-3 part of brown algae extract and 80.4607-96.86497 parts of water; the water comprises water A and water B, and the weight ratio of the water A to the water B is as follows: (80.46-96.85): (0.0001497-0.01497).

Meanwhile, the invention discloses a preparation method of the anti-aging firming mask liquid, which comprises the following steps:

(1) Mixing and compounding butanediol, water B, polyvinylpyrrolidone and fullerene in the phase E to prepare a butanediol/water/polyvinylpyrrolidone/fullerene compound; then uniformly mixing the butanediol/water/polyvinylpyrrolidone/fullerene compound with other components in the E phase to prepare an E phase mixture;

uniformly mixing the components in the phase B, the phase C and the phase D respectively to prepare a phase B mixture, a phase C mixture and a phase D mixture;

(2) After the step (1) is finished, uniformly mixing xanthan gum, hydroxyethyl cellulose and glycerol in the phase A, adding the mixture into an emulsifying pot, respectively adding the rest raw materials in the phase A, stirring, heating to 80-85 ℃, and then preserving heat;

(3) After the step (2) is finished, cooling to below 45 ℃, adding the phase B, the phase C and the phase E into an emulsifying pot, and stirring until the mixture is uniformly stirred;

(4) And (4) after the step (3) is finished, adding the phase D, uniformly stirring and then discharging.

Preferably, the temperature keeping time in the step (2) is 20-30 minutes.

Compared with the prior art, the invention has the beneficial effects that: the anti-aging firming mask liquid provided by the invention is safe and non-irritant, has good oxidation resistance, and can slow down skin aging symptoms, tighten skin and restore skin cell activity. In addition, the preparation method of the anti-aging compact facial mask liquid provided by the invention is simple in process, can be prepared by only less equipment, and is suitable for industrial mass production.

Detailed Description

To better illustrate the objects, aspects and advantages of the present invention, the present invention will be further described with reference to specific examples.

The formulations of examples 1 to 5 and comparative examples 1 to 4 are shown in table 1, wherein the composition of part of the humectant, thickener and preservative in comparative example 1 is absent from the formulation of butanediol/water/polyvinylpyrrolidone/fullerene, in comparative example 2 is absent from the formulation of rebaudioside, in comparative example 3 is absent from the formulation of brown algae, and in comparative example 4 the composition of the humectant, thickener and preservative is not within the scope of the present disclosure, and the remaining components are the same as in example 1 except for the above differences in the components and water content.

TABLE 1 formulations (parts by weight) of examples 1 to 5 and comparative examples 1 to 4

Performance testing

1. Moisture retention test

The moisture retentions of examples 1 to 5 and comparative examples 1 to 4 were measured using a multifunctional skin tester at an ambient temperature of 23. + -. 1 ℃ and a humidity of 55. + -. 5%; the subjects were 90 persons in total, divided into 9 groups, aged between 18-40 years, and the subjects were treated before the test by washing the inner side of the forearm with a mild cleanser in a unified manner and drawing out 3X 3cm on the left and right forearms ² The size and the position of the square test area are symmetrical, the left arm is used as the test area, the right arm is used as a blank control, a tester sits for 30min in a static environment at constant temperature after smearing a test article, then the moisture content of the skin is measured by a Corneometer moisture test probe, the test result of the left arm in each time is divided by the test result of the blank area of the right arm, and the hydration value is taken as a hydration value, and the test result of the hydration value is shown in a table 3.

2. Irritation test

The test is a blood vessel test of the chick embryo chorioallantoic membrane according to SN/T2329-2009, and the chick embryo chorioallantoic membrane blood vessel test is an in-vitro method of an eye stimulation test and is used for evaluating the stimulation degree of a tested body to eyes and evaluating the stimulation and safety degree of a product.

The experimental method comprises the following steps: using fertilized chicken embryos incubated for 10-12 days as experimental samples, marking the positions of air chambers on the surfaces of the eggshells, and stripping off the marked eggshells by using dental sawtooth bending forceps to expose white eggshell membranes; sucking a proper amount of sodium chloride solution with the mass fraction of 0.9% by using a suction pipe to wet the egg membrane, and pouring out the redundant solution; then carefully remove the intima with forceps to ensure the vascular membrane is not damaged. A PTFE ring was placed on the intact chick embryo chorioallantoic membrane as the test area for the test sample. By utilizing the characteristics of completeness, clearness and transparency of chorioallantoic vessels of fertilized chick embryos, 0.3mL of each of the facial mask solutions of the above examples 1 to 5 and comparative examples 1 to 4 was taken, a sample was diluted with 0.9wt.% of a sodium chloride solution until the concentration was 3wt.%,0.9wt.% of a sodium chloride solution as a negative control group, and 0.3wt.% of a sodium hydroxide solution as a positive control group, and the diluted sample was dropped onto a test area of a chick embryo, covered with a wet preservative film on an air chamber, and then placed in a 37 ℃ incubator for 30min. The cultured chick embryos were irradiated with a lamp tube and the degree of damage to the blood vessels was observed and scored. 10 chick embryos are made for each sample, the irritation value is recorded, experimental data are screened by a Q value inspection method, and a weighted average value, namely an NC value, is calculated. The evaluation reference standard is shown in table 2, and the test results are shown in table 3.

TABLE 2 irritation evaluation criteria

3. Resistance to aging test

Selecting 90 female mice with the age of 12 months old from nature, dividing into 9 groups, breeding the mice in cages, feeding the mice normally under the conditions of cleanness, ventilation, dryness and room temperature (23 +/-1 ℃), and starting the test after adaptive breeding. Depilating both sides of spinal column and skin near hip 24h before experiment, cleaning depilatory cream residue with warm water to expose 3 × 3cm ² The range of skin tested was then depilated once daily in the same manner so as not to affect the test effect.

According to the weight of a mouse, the facial mask liquid is smeared on the skin of a test in a dose of 0.5g/100g, after smearing, a preservative film is used for local coverage, and then medical gauze is used for protection for 60min for 1 time every day. Each group was administered for 30d consecutively. The mice were anesthetized on day 31, and 0.5g (about 0.5X 0.5 cm) of the skin was rapidly collected ² ) And carrying out biochemical index test after rinsing by normal saline. The SOD test results are shown in Table 3.

4. Tightness test

The test method comprises the following steps: 90 volunteers aged 30-45 years, with wrinkles but no skin damage, were selected and randomly divided into 9 groups. 25g of the facial mask solutions prepared in examples 1 to 5 and comparative examples 1 to 4 were dropped on the nonwoven fabric facial mask patch to prepare facial mask products. After washing the face of the subject every night, the facial masks prepared in examples 1 to 5 and comparative examples 1 to 4 were used continuously for 4 weeks 3 times per week. During the experiment, the subject was not painted with any other cosmetic.

And (3) using a skin elasticity meter MPA580 to respectively acquire data when the skin elasticity meter is not used and at the 4 th week, wherein the test part is a cheekbone part, and the probe repeatedly measures for 3 times in the same measured area during measurement, and an average value is taken. The test parameter is R2 (the ratio of the amount of springback Ua of the skin without negative pressure to the amount of maximum stretch Uf with negative pressure), and the closer R2 is to 1, the better the elasticity of the skin. Mean rate of change of R2 = (week 4R 2 value-week 0R 2 value)/week 0R 2 value. The test results are shown in Table 3.

Table 3 results of performance testing

As can be seen from Table 3, examples 1 to 5 all had better anti-aging and firming effects than comparative examples 1 to 4, and the moisture retention was maintained at a higher level and the irritation was less. In addition, the best overall performance of example 1 is shown in the examples, which indicates that the formulation described in example 1 has the best synergistic effect among the ingredients. The results show that the facial mask liquid prepared from the components in proportion has good anti-aging and firming properties, the preparation process is simple, the used equipment is less, and the facial mask liquid is suitable for industrial production.

Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting the protection scope of the present invention, and although the present invention has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions can be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.

Claims (3)

1. The anti-aging firming mask liquid is characterized by comprising an A phase, a B phase, a C phase, a D phase and an E phase, wherein the A phase comprises the following components in parts by weight: 2-6 parts of glycerol, 0.05-0.3 part of xanthan gum, 0.5-3 parts of trehalose, 0.005-0.04 part of sodium hyaluronate, 0.005-0.05 part of hydroxyethyl cellulose, 0.005-0.15 part of methyl hydroxybenzoate, 0.05-0.6 part of p-hydroxyacetophenone and 80.46-96.85 parts of water A; the phase B comprises the following components in parts by weight: 0.0045 to 0.63 portion of phenoxyethanol and 0.0005 to 0.07 portion of ethylhexyl glycerol; the phase C comprises the following components in parts by weight: 0.0005 to 0.1 part of essence and 0.002 to 0.4 part of PEG-40 hydrogenated castor oil; the phase D comprises the following components in parts by weight: 0.5-3 parts of propylene glycol and 0.001-0.1 part of polyethylene glycol-115M; the phase E comprises the following components in parts by weight: 0.00075 to 0.075 portion of butanediol, 0.0001 to 0.01 portion of polyvinylpyrrolidone, 0.0000003 to 0.00003 portion of fullerene, 0.01 to 2 portions of stevioside, 0.01 to 3 portions of brown algae extract and 0.0001497 to 0.01497 portion of water B.

2. A method for preparing the anti-aging firming mask solution as defined in claim 1, which comprises the following steps:

(1) Mixing and compounding butanediol, water B, polyvinylpyrrolidone and fullerene in the phase E to prepare a butanediol/water/polyvinylpyrrolidone/fullerene compound; then uniformly mixing the butanediol/water/polyvinylpyrrolidone/fullerene compound with other components in the phase E to prepare a phase E mixture;

uniformly mixing the components in the B phase, the C phase and the D phase respectively to prepare a B phase mixture, a C phase mixture and a D phase mixture;

(2) After the step (1) is finished, uniformly mixing xanthan gum, hydroxyethyl cellulose and glycerol in the phase A, adding the mixture into an emulsifying pot, respectively adding the rest raw materials in the phase A, stirring, heating to 80-85 ℃, and then preserving heat;

(3) After the step (2) is finished, cooling to below 45 ℃, adding the phase B, the phase C and the phase E into an emulsifying pot, and stirring until the mixture is uniformly stirred;

(4) And (4) after the step (3) is finished, adding the phase D, uniformly stirring and then discharging.

3. The method for preparing the anti-aging & firming mask solution according to claim 2, wherein the heat preservation time in the step (2) is 20 to 30 minutes.