CN111729051A - 一种治疗高血压的穴位贴及其制备方法 - Google Patents
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Abstract
本发明提供一种治疗高血压的穴位贴,它由如下重量份数的原料制备得到:宣木瓜25‑35份、钝顶螺旋藻20‑30份、刺梨15‑25份、榧子10‑15份、葛根10‑25份、沙棘叶10‑20份、桃仁10‑15份、益智仁5‑10份,并采用了相应的制备方法制备而成。本发明作为一种纯中药制剂,疗效独特,穿透和吸收能力极强,贴附于相应穴位后,能安全有效治疗高血压,且无毒副作用。
Description
技术领域
本发明属中药制剂加工技术领域,具体涉及一种治疗高血压的穴位贴及其制备方法。
背景技术
高血压(hypertension)是指以体循环动脉血压(收缩压和/或舒张压)增高为主要特征(收缩压≥140毫米汞柱,舒张压≥90毫米汞柱),可伴有心、脑、肾等器官的功能或器质性损害的临床综合征。高血压是最常见的慢性病,也是心脑血管病最主要的危险因素。正常人的血压随内外环境变化在一定范围内波动。在整体人群,血压水平随年龄逐渐升高,以收缩压更为明显,但50岁后舒张压呈现下降趋势,脉压也随之加大。近年来,人们对心血管病多重危险因素的作用以及心、脑、肾靶器官保护的认识不断深入,高血压的诊断标准也在不断调整,目前认为同一血压水平的患者发生心血管病的危险不同,因此有了血压分层的概念,即发生心血管病危险度不同的患者,适宜血压水平应有不同。血压值和危险因素评估是诊断和制定高血压治疗方案的主要依据,不同患者高血压管理的目标不同,医生面对患者时在参考标准的基础上,根据其具体情况判断该患者最合适的血压范围,采用针对性的治疗措施。在改善生活方式的基础上,推荐使用24小时长效降压药物控制血压。除评估诊室血压外,患者还应注意家庭清晨血压的监测和管理,以控制血压,降低心脑血管事件的发生率。目前缺少安全有效治疗、控制血压的中药组合物。
发明内容
发明目的:为解决上述问题,本发明提供了一种治疗高血压的穴位贴。
技术方案:一种治疗高血压的穴位贴,它由如下重量份数的原料药提取制备得到:宣木瓜25-35份、钝顶螺旋藻20-30份、刺梨15-25份、榧子10-15份、葛根10-25份、沙棘叶10-20份、桃仁10-15份、益智仁5-10份、蜂蜜3-5份。
所述治疗高血压的穴位贴,它由如下最优重量份数的原料药提取制备得到:宣木瓜30份、钝顶螺旋藻25份、刺梨20份、榧子12份、葛根18份、沙棘叶15份、桃仁13份、益智仁7份、蜂蜜4份。
所述治疗高血压的穴位贴,包括无纺布背衬层、药物层、聚乙烯薄膜覆盖层。
所述治疗高血压的穴位贴,所述药物层,包括中药材混合提取物,为所述原料经提取后添加辅料制成膏糊状,依附在背衬层,并用聚乙烯薄膜覆盖。
所述治疗高血压的穴位贴,所述中药材混合提取物,制备方法如下:取宣木瓜、钝顶螺旋藻、刺梨、榧子、葛根、沙棘叶、桃仁、益智仁合并,加水煎煮两次,合并煎液,浓缩至65℃时相对密度为1.10-1.20,加入乙醇,搅拌,使含醇量按体积百分比计算达65-75%,静置,过滤,滤液减压浓缩至65℃时相对密度为1.20-1.30,回收乙醇得浓缩液,将适量蜂蜜加入浓缩液中,混合均匀,按常规方法熬制成膏糊状,制成贴剂。
所述治疗高血压的穴位贴,制备方法中煎煮条件为:第一次加水量为药材重量的6-8倍量,煎煮1-2h,第二次加水量为药材重量的4-5倍量,煎煮1-2h。
有益效果:本发明作为一种纯中药制剂,疗效独特,穿透和吸收能力极强,贴附于相应穴位后,能安全有效治疗高血压,且无毒副作用。
具体实施方式
以下通过实施例形式对本发明的上述内容再作进一步的详细说明。
实施例1:取宣木瓜25份、钝顶螺旋藻20份、刺梨15份、榧子10份、葛根10份、沙棘叶10份、桃仁10份、益智仁5份合并,加水煎煮两次,第一次加水为药材重量的6倍量,煎煮1h,第二次加水为药材重量的4倍量,煎煮1h,合并煎液,浓缩至65℃时相对密度为1.10-1.20,加入乙醇,搅拌,使含醇量按体积百分比计算达65-75%,静置,过滤,滤液减压浓缩至65℃时相对密度为1.20-1.30,回收乙醇得浓缩液,将3份蜂蜜加入浓缩液中,混合均匀,按常规方法熬制成膏糊状,制成贴剂。
实施例2:取宣木瓜30份、钝顶螺旋藻25份、刺梨20份、榧子12份、葛根18份、沙棘叶15份、桃仁13份、益智仁7份合并,加水煎煮两次,第一次加水为药材重量的7倍量,煎煮1.5h,第二次加水为药材重量的4.5倍量,煎煮1.5h,合并煎液,浓缩至65℃时相对密度为1.10-1.20,加入乙醇,搅拌,使含醇量按体积百分比计算达65-75%,静置,过滤,滤液减压浓缩至65℃时相对密度为1.20-1.30,回收乙醇得浓缩液,将4份蜂蜜加入浓缩液中,混合均匀,按常规方法熬制成膏糊状,制成贴剂。
实施例3:取宣木瓜35份、钝顶螺旋藻30份、刺梨25份、榧子15份、葛根25份、沙棘叶20份、桃仁15份、益智仁10份合并,加水煎煮两次,第一次加水为药材重量的8倍量,煎煮2h,第二次加水为药材重量的5倍量,煎煮2h,合并煎液,浓缩至65℃时相对密度为1.10-1.20,加入乙醇,搅拌,使含醇量按体积百分比计算达65-75%,静置,过滤,滤液减压浓缩至65℃时相对密度为1.20-1.30,回收乙醇得浓缩液,将5份蜂蜜加入浓缩液中,混合均匀,按常规方法熬制成膏糊状,制成贴剂。
Claims (6)
1.一种治疗高血压的穴位贴,其特征在于,它由如下重量份数的原料药提取制备得到:宣木瓜25-35份、钝顶螺旋藻20-30份、刺梨15-25份、榧子10-15份、葛根10-25份、沙棘叶10-20份、桃仁10-15份、益智仁5-10份、蜂蜜3-5份。
2.如权利要求1所述治疗高血压的穴位贴,其特征在于,它由如下最优重量份数的原料药提取制备得到:宣木瓜30份、钝顶螺旋藻25份、刺梨20份、榧子12份、葛根18份、沙棘叶15份、桃仁13份、益智仁7份、蜂蜜4份。
3.如权利要求1所述治疗高血压的穴位贴,其特征在于,所述穴位贴包括无纺布背衬层、药物层、聚乙烯薄膜覆盖层。
4.如权利要求1所述治疗高血压的穴位贴,其特征在于,所述药物层,包括中药材混合提取物,为所述原料经提取后添加辅料制成膏糊状,依附在背衬层,并用聚乙烯薄膜覆盖。
5.如权利要求1所述治疗高血压的穴位贴,其特征在于,所述中药材混合提取物,制备方法如下:取宣木瓜、钝顶螺旋藻、刺梨、榧子、葛根、沙棘叶、桃仁、益智仁合并,加水煎煮两次,合并煎液,浓缩至65℃时相对密度为1.10-1.20,加入乙醇,搅拌,使含醇量按体积百分比计算达65-75%,静置,过滤,滤液减压浓缩至65℃时相对密度为1.20-1.30,回收乙醇得浓缩液,将适量蜂蜜加入浓缩液中,混合均匀,按常规方法熬制成膏糊状,制成贴剂。
6.如权利要求1所述治疗高血压的穴位贴,其特征在于,制备方法中煎煮条件为:第一次加水量为药材重量的6-8倍量,煎煮1-2h;第二次加水量为药材重量的4-5倍量,煎煮1-2h。
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