CN111729042A

CN111729042A - Medicine for treating oral ulcer and preparation method thereof

Info

Publication number: CN111729042A
Application number: CN202010707545.1A
Authority: CN
Inventors: 李成
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-07-21
Filing date: 2020-07-21
Publication date: 2020-10-02

Abstract

The invention discloses a medicament for treating oral ulcer, which comprises the following formula: the weight portion of the material is as follows: 1-25 parts of coreopsis tinctoria, 1-20 parts of radix sophorae flavescentis, 5-40 parts of calendula officinalis, 6-30 parts of schizonepeta, 8-50 parts of corn stigma, 10-40 parts of ailanthus bark, 10-15 parts of phaseolus calcaratus, 10-45 parts of narcissus, 10-25 parts of red paeony root, 10-40 parts of sculellaria barbata and 1-5 parts of borax. The preparation method of the medicine for treating the dental ulcer, which is provided by the invention, has the advantages of simple, scientific and reasonable steps, capability of avoiding the occurrence of an accident of drug poisoning caused by the restriction of food and medicine, higher safety, smaller requirement on the size of the granularity of the medicine, better practicability and higher grinding efficiency.

Description

Medicine for treating oral ulcer and preparation method thereof

Technical Field

The invention relates to the technical field of traditional Chinese medicines, in particular to a medicine for treating oral ulcer and a preparation method thereof.

Background

The Chinese traditional medicine is collected, processed and prepared under the guidance of Chinese traditional medicine theory, explains the action mechanism and guides the medicines for clinical application, and is generally called as Chinese traditional medicine. In short, a Chinese medicine is a substance which is used for preventing, treating and diagnosing diseases and has the effects of rehabilitation and health care under the guidance of the theory of traditional Chinese medicine. The Chinese medicine is mainly prepared from natural medicines and processed products thereof, including plant medicines, animal medicines, mineral medicines and partial chemical and biological products. Because the traditional Chinese medicines are mostly prepared from plant medicines, there is a saying that the medicines are prepared from herbs.

The medicine for treating oral ulcer in the prior art generally contains chemical components, has side effects, has low cure rate for treating recurrent oral ulcer diseases, and is easy to relapse after being cured; in addition, the preparation method of the medicine for treating the dental ulcer in the prior art has complicated and unreasonable steps, generally adopts an oral administration mode, can not avoid the occurrence of accidents of medicine poisoning caused by the mutual restriction of food and medicine, has poor safety and is difficult to use safely; in addition, the grinding machine used in the process of preparing the medicine for treating the dental ulcer in the prior art has higher requirement on the size limit of the granularity of the medicine, has poor practicability and has low grinding efficiency.

Therefore, a medicament for treating oral ulcer and a preparation method thereof are provided.

Disclosure of Invention

Aiming at the defects in the prior art, the invention aims to provide a medicament for treating oral ulcer and a preparation method thereof, so as to solve the problems in the background technology.

In order to achieve the purpose, the invention provides the following technical scheme:

a medicine for treating oral ulcer comprises the following formula:

the weight portion of the material is as follows: 1-25 parts of coreopsis tinctoria, 1-20 parts of radix sophorae flavescentis, 5-40 parts of calendula officinalis, 6-30 parts of schizonepeta, 8-50 parts of corn stigma, 10-40 parts of ailanthus bark, 10-15 parts of phaseolus calcaratus, 10-45 parts of narcissus, 10-25 parts of red paeony root, 10-40 parts of sculellaria barbata and 1-5 parts of borax.

Further, the weight portions are as follows: also comprises 1-8 parts of mint.

Further, the weight portions are as follows: also comprises 3-10 parts of fig leaves.

Further, the weight portions are as follows: also comprises 10-30 parts of cogongrass rhizome.

Further, the weight portions are as follows: also comprises 10-30 parts of reed rhizome.

The invention also provides a preparation method of the medicine for treating the oral ulcer, which comprises the following steps:

s1, weighing 1-25 parts of coreopsis tinctoria, 1-20 parts of radix sophorae flavescentis, 5-40 parts of calendula officinalis, 6-30 parts of schizonepeta, 8-50 parts of corn stigma, 10-40 parts of ailanthus altissima swingle, 10-15 parts of phaseolus calcaratus, 10-45 parts of narcissus chinensis, 10-25 parts of red paeony root, 10-40 parts of sculellaria barbata and 1-5 parts of borax in parts by weight;

s2, boiling the weighed red beans with clear water, drying in the sun, mixing with the weighed daffodil and red peony root, and grinding into powder by a grinder to obtain the powder raw material

S3, mixing folium Stephaniae Tetrandrae, cortex Ailanthi and stigma Maydis, adding into sealed jar, and processing with pure grain wine for 7 days;

s4, after the coreopsis tinctoria, the ailanthus altissima swingle and the corn in the step S3 are processed by the pure grain wine for 7 days, opening the sealing tank, adding all the sophora flavescens, the calendula officinalis, the schizonepeta, the sculellaria barbata, the borax and the powder raw materials prepared in the step S2 into the sealing tank, sealing and storing at normal temperature for 7 days;

s5, opening the sealed tank in the step S4 after 7 days, filtering out pure grain wine in the sealed tank by using a stainless steel filter screen with the mesh number of 50, boiling the obtained filtrate for 5-10 minutes by using mild fire, and cooling the filtrate to obtain the medicine for treating dental ulcer.

Furthermore, the using amount of the pure grain wine is 100-300 parts by weight.

Further, the grinding machine comprises a base, a shell, a grinding cylinder, a material port, an end cover and a grinding mechanism, wherein the base is a circular base, the shell is fixedly installed on the upper portion of the base, the bottom end of the grinding cylinder is of a closed structure, the grinding cylinder is fixedly installed inside the shell, the material port is a cylindrical material port, the material port is fixedly installed at the upper end portion of the grinding cylinder, the inner diameter of the material port is smaller than that of the grinding cylinder, and the end cover is arranged outside the material port in a covering mode;

wherein, the grinding mechanism comprises a motor, a stirring shaft, a matching seat, two grinding blocks and two grinding blades, the motor is fixedly arranged at the upper part of the base, the motor is positioned inside the shell, the stirring shaft is fixedly arranged at the central position of the end wall at the bottom end of the grinding cylinder through a sealed bearing, the bottom end of the stirring shaft is fixedly connected with a rotating shaft of the motor through a coupler, the matching seat is fixedly arranged at the upper end of the stirring shaft, the two grinding blocks are fixedly arranged at the lateral part of the matching seat through a cross rod, the two grinding blocks are symmetrically arranged, the two grinding blades are fixedly arranged at the lateral part of the matching seat through connecting blocks, the two grinding blades are symmetrically arranged, and the connecting line between the two grinding blades is vertical to the connecting line between the two grinding blocks, the two crushing blades, the two grinding blocks and the assembling seat are all positioned in the grinding cylinder.

Further, still fixed mounting has control switch on the lateral surface of shell, control switch pass through the wire with the motor series connection.

Furthermore, the bottom of the base is also fixedly provided with four support legs, and the four support legs are annularly arranged at equal angles.

In summary, the invention mainly has the following beneficial effects:

1. the medicine for treating oral ulcer provided by the invention is prepared from pure traditional Chinese medicines such as coreopsis tinctoria, sophora flavescens, calendula officinalis, schizonepeta, corn stigma, ailanthus altissima bark, phaseolus calcaratus, narcissus, red paeony root, barbed skullcap herb, borax and the like, does not contain chemical components, basically has no side effect, and particularly has higher cure rate for treating recurrent oral ulcer diseases, is not easy to relapse after being cured, and is worthy of popularization and promotion;

2. the preparation method of the medicine for treating the dental ulcer, provided by the invention, has simple, scientific and reasonable steps, and the prepared medicine for treating the dental ulcer is used for gargling instead of oral administration, so that the occurrence of an accident of drug poisoning caused by mutual restriction of food and medicine can be avoided, and the medicine for treating the dental ulcer is higher in safety and can be used safely;

3. the grinding machine used in the process of preparing the medicine for treating the dental ulcer mainly comprises a base, a shell, a grinding cylinder, a material port, an end cover and a grinding mechanism, wherein the grinding mechanism comprises a motor, a stirring shaft, a matching seat, two grinding blocks and two grinding blades.

Drawings

FIG. 1 is a schematic view of a grinder in one embodiment;

FIG. 2 is a schematic diagram of an exploded structure of a grinding mill in one embodiment;

FIG. 3 is a schematic view of another perspective of a grinder in one embodiment;

FIG. 4 is an exploded view from another perspective of a grinding mill in one embodiment;

FIG. 5 is an enlarged view of the structure at A in FIG. 4;

FIG. 6 is a partial cross-sectional structural view of a grinding mill in one embodiment;

FIG. 7 is a schematic view, partly in section, of another perspective of a grinding mill in one embodiment;

fig. 8 is an enlarged schematic view of the structure at B in fig. 7.

In the figure: 1. a base; 2. a housing; 3. a grinding cylinder; 4. a material port; 5. an end cap; 6. a control switch; 7. a grinding mechanism; 701. a motor; 702. a stirring shaft; 703. a coupling; 704. sealing the bearing; 705. a crushing blade; 706. grinding blocks; 707. a cross bar; 708. assembling a base; 709. connecting blocks; 8. and (3) a support leg.

Detailed Description

The present invention is described in further detail below with reference to figures 1-8.

Example 1

A medicine for treating oral ulcer comprises the following formula:

Example 2

A medicine for treating oral ulcer comprises the following formula:

the weight portion of the material is as follows: 1-25 parts of coreopsis tinctoria, 1-20 parts of radix sophorae flavescentis, 5-40 parts of calendula officinalis, 6-30 parts of schizonepeta, 8-50 parts of corn stigma, 10-40 parts of ailanthus bark, 10-15 parts of phaseolus calcaratus, 10-45 parts of narcissus, 10-25 parts of red paeony root, 10-40 parts of sculellaria barbata, 1-5 parts of borax and 1-8 parts of mint.

Example 3

A medicine for treating oral ulcer comprises the following formula:

the weight portion of the material is as follows: 1-25 parts of coreopsis tinctoria, 1-20 parts of radix sophorae flavescentis, 5-40 parts of calendula officinalis, 6-30 parts of schizonepeta, 8-50 parts of corn stigma, 10-40 parts of ailanthus bark, 10-15 parts of phaseolus calcaratus, 10-45 parts of narcissus, 10-25 parts of red paeony root, 10-40 parts of sculellaria barbata, 1-5 parts of borax and 3-10 parts of fig leaves.

Example 4

A medicine for treating oral ulcer comprises the following formula:

the weight portion of the material is as follows: 1-25 parts of coreopsis tinctoria, 1-20 parts of radix sophorae flavescentis, 5-40 parts of calendula officinalis, 6-30 parts of schizonepeta, 8-50 parts of corn stigma, 10-40 parts of ailanthus bark, 10-15 parts of phaseolus calcaratus, 10-45 parts of narcissus, 10-25 parts of red paeony root, 10-40 parts of sculellaria barbata, 1-5 parts of borax and 10-30 parts of lalang grass rhizome.

Example 5

A medicine for treating oral ulcer comprises the following formula:

the weight portion of the material is as follows: 1-25 parts of coreopsis tinctoria, 1-20 parts of radix sophorae flavescentis, 5-40 parts of calendula officinalis, 6-30 parts of schizonepeta, 8-50 parts of corn stigma, 10-40 parts of ailanthus bark, 10-15 parts of phaseolus calcaratus, 10-45 parts of narcissus, 10-25 parts of red paeony root, 10-40 parts of sculellaria barbata, 1-5 parts of borax and 10-30 parts of reed rhizome.

Example 6

A medicine for treating oral ulcer comprises the following formula: the weight portion of the material is as follows: 1-25 parts of coreopsis tinctoria, 1-20 parts of radix sophorae flavescentis, 5-40 parts of calendula officinalis, 6-30 parts of schizonepeta, 8-50 parts of corn stigma, 10-40 parts of ailanthus bark, 10-15 parts of phaseolus calcaratus, 10-45 parts of narcissus, 10-25 parts of red paeony root, 10-40 parts of sculellaria barbata, 1-5 parts of borax, 1-8 parts of mint, 3-10 parts of fig leaves, 10-30 parts of lalang grass rhizome and 10-30 parts of reed rhizome.

Example 7

s1, weighing 10 parts of coreopsis tinctoria, 15 parts of radix sophorae flavescentis, 25 parts of calendula officinalis, 20 parts of schizonepeta, 30 parts of corn stigma, 30 parts of ailanthus altissima swingle, 13 parts of phaseolus calcaratus, 35 parts of narcissus, 18 parts of radix paeoniae rubra, 30 parts of sculellaria barbata and 3 parts of borax in parts by weight;

Preferably, the pure grain wine is used in an amount of 200 parts by weight.

Example 8

The difference between the embodiment and the embodiment 7 is that 10 parts of coreopsis sisalata, 15 parts of sophora flavescens, 25 parts of calendula officinalis, 20 parts of schizonepeta, 30 parts of corn stigma, 30 parts of ailanthus altissima swingle, 13 parts of phaseolus calcaratus, 35 parts of narcissus, 18 parts of red paeony root, 30 parts of sculellaria barbata, 3 parts of borax and 5 parts of mint are weighed according to the parts by weight.

The difference between the embodiment and the embodiment 7 is that 10 parts of coreopsis sisalata, 15 parts of sophora flavescens, 25 parts of calendula officinalis, 20 parts of schizonepeta, 30 parts of corn stigma, 30 parts of ailanthus bark, 13 parts of phaseolus calcaratus, 35 parts of narcissus, 18 parts of red paeony root, 30 parts of sculellaria barbata, 3 parts of borax and 7 parts of fig leaves are weighed according to the parts by weight

Example 10

The difference between the embodiment and the embodiment 7 is that 10 parts of coreopsis sisalata, 15 parts of sophora flavescens, 25 parts of calendula officinalis, 20 parts of schizonepeta, 30 parts of corn stigma, 30 parts of ailanthus bark, 13 parts of phaseolus calcaratus, 35 parts of narcissus, 18 parts of red paeony root, 30 parts of sculellaria barbata, 3 parts of borax and 20 parts of lalang grass rhizome are weighed according to the parts by weight.

Example 11

The difference between the embodiment and the embodiment 7 is that 10 parts of coreopsis sisalata, 15 parts of sophora flavescens, 25 parts of calendula officinalis, 20 parts of schizonepeta, 30 parts of corn stigma, 30 parts of ailanthus bark, 13 parts of phaseolus calcaratus, 35 parts of narcissus, 18 parts of red paeony root, 30 parts of sculellaria barbata, 3 parts of borax and 20 parts of reed rhizome are weighed according to the parts by weight.

Example 12

The difference between the embodiment and the embodiment 7 is that 10 parts of coreopsis tigrina, 15 parts of sophora flavescens, 25 parts of calendula, 20 parts of schizonepeta, 30 parts of corn stigma, 30 parts of ailanthus bark, 13 parts of phaseolus calcaratus, 35 parts of narcissus, 18 parts of red paeony root, 30 parts of sculellaria barbata, 3 parts of borax, 5 parts of mint, 7 parts of fig leaves, 20 parts of lalang grass rhizome and 20 parts of reed rhizome are weighed according to the parts by weight.

The mints, fig leaves, cogongrass rhizome and reed rhizome according to examples 8 to 12 were all stored in a sealed can at room temperature for 7 days by being sealed in a sealed container at step S4.

The grinding machines in embodiments 1 to 12 each include a base 1, a housing 2, a grinding cylinder 3, a material port 4, an end cover 5, and a grinding mechanism 7, where the base 1 is a circular base, the housing 2 is fixedly mounted on the upper portion of the base 1, the bottom end of the grinding cylinder 3 is a closed structure, the grinding cylinder 3 is fixedly mounted inside the housing 2, the material port 4 is a cylindrical material port, the material port 4 is fixedly mounted on the upper end portion of the grinding cylinder 3, the inner diameter of the material port 4 is smaller than the inner diameter of the grinding cylinder 3, and the end cover 5 covers the material port 4;

wherein, the grinding mechanism 7 comprises a motor 701, a stirring shaft 702, a fitting seat 708, two grinding blocks 706 and two crushing blades 705, the motor 701 is fixedly arranged at the upper part of the base 1, the motor 701 is positioned in the shell 2, the stirring shaft 702 is fixedly arranged at the central position of the end wall of the bottom end of the grinding cylinder 3 through a sealed bearing 704, the bottom end of the stirring shaft 702 is fixedly connected with the rotating shaft of the motor 701 through a coupler 703, the fitting seat 708 is fixedly arranged at the upper end of the stirring shaft 702, the two grinding blocks 706 are fixedly arranged at the side part of the fitting seat 708 through a cross bar 707, the two grinding blocks 706 are symmetrically arranged, the two crushing blades 705 are fixedly arranged at the side part of the fitting seat 708 through a connecting block 709, the two crushing blades 705 are symmetrically arranged, the connecting line between the two crushing blades 705 is vertical to the connecting line between the two grinding blocks 706, the two crushing blades 705, the two grinding blocks 706 and the assembling seat 708 are all located inside the grinding cylinder 3, a control switch 6 is further fixedly installed on the outer side surface of the shell 2, the control switch 6 is connected with the motor 701 in series through a wire, four support legs 8 are further fixedly installed at the bottom of the base 1, and the four support legs 8 are annularly arranged at equal angles.

Clinical verification shows that the medicaments for treating oral ulcer prepared in the above examples 1 to 12 are used in a mouth wash mode, each mouth wash is performed once after breakfast, lunch and supper every day, the amount of the medicament used in each mouth wash is 100ml, and then the statistical results of the healing conditions of the oral ulcer of the medicaments for treating oral ulcer prepared in the examples 1 to 12 are as follows:

the statistical results in the table show that the example 12 is the optimal example, and by adopting the technical scheme, the proposed medicine for treating oral ulcer is composed of pure traditional Chinese medicines, does not contain chemical components, has no side effects basically, has high cure rate especially for treating recurrent oral ulcer diseases, is not easy to relapse after healing, and is worthy of popularization and promotion.

In summary, the following steps:

the medicine for treating oral ulcer provided by the invention is prepared from pure traditional Chinese medicines such as coreopsis tinctoria, sophora flavescens, calendula officinalis, schizonepeta, corn stigma, ailanthus altissima bark, phaseolus calcaratus, narcissus, red paeony root, barbed skullcap herb, borax and the like, does not contain chemical components, basically has no side effect, and particularly has higher cure rate for treating recurrent oral ulcer diseases, is not easy to relapse after being cured, and is worthy of popularization and promotion;

the preparation method of the medicine for treating the dental ulcer provided by the invention has simple, scientific and reasonable steps, and the prepared medicine for treating the dental ulcer is used for gargling instead of oral administration, so that the occurrence of an accident of drug poisoning caused by mutual restriction of food and medicine can be avoided, and the medicine for treating the dental ulcer has higher safety and can be used safely.

The grinder used in the process of preparing the medicine for treating the dental ulcer mainly comprises a base 1, a shell 2, a grinding cylinder 3, a material port 4, an end cover 5 and a grinding mechanism 7, wherein the grinding mechanism 7 comprises a motor 701, a stirring shaft 702, a mounting seat 708, two grinding blocks 706 and two grinding blades 705, when the grinder is used, the medicine with larger granularity can be ground by the two grinding blades 705, and the medicine with smaller granularity can be ground by the two grinding blocks 706, so that the requirement on the size limitation of the granularity of the medicine by the grinder is smaller, the practicability of the grinder is better, and in addition, under the condition that the two grinding blocks 706 and the two grinding blades 705 are matched with each other for use, the grinding efficiency of the grinder is higher.

The use method of the grinder is as follows: during the use, open end cover 5, then the inside of grinding vessel 3 is added through material mouth 4 to the raw materials that will grind, cover 5 lid in the outside of material mouth 4 again, then through control switch 6 control motor 701 operation, motor 701 drives two crushing blade 705 and two grinding block 706 high-speed rotations, two crushing blade 705 smash the great medicine of granularity, two grinding block 706 carry out the crocus to the less medicine of granularity simultaneously, finally practice the purpose of that quick crocus, after standing at least 10 minutes after grinding well, open end cover 5 again, pour out the inside crocus of grinding vessel 3 can.

The parts not involved in the present invention are the same as or can be implemented by the prior art. The present embodiment is only for explaining the present invention, and it is not limited to the present invention, and those skilled in the art can make modifications of the present embodiment without inventive contribution as needed after reading the present specification, but all of them are protected by patent law within the scope of the claims of the present invention.

Claims

1. A medicament for treating oral ulcers, which is characterized in that: the formula comprises the following components:

2. The medicament for treating the oral ulcer according to claim 1, wherein: the weight portion of the material is as follows: also comprises 1-8 parts of mint.

3. The medicament for treating the oral ulcer according to claim 1, wherein: the weight portion of the material is as follows: also comprises 3-10 parts of fig leaves.

4. The medicament for treating the oral ulcer according to claim 1, wherein: the weight portion of the material is as follows: also comprises 10-30 parts of cogongrass rhizome.

5. The medicament for treating the oral ulcer according to claim 1, wherein:

the weight portion of the material is as follows: also comprises 10-30 parts of reed rhizome.

6. A preparation method of a medicine for treating oral ulcer is characterized by comprising the following steps: the method comprises the following steps:

7. The method for preparing a medicament for treating oral ulcer according to claim 6, wherein: the usage amount of the pure grain wine is 100-300 parts by weight.

8. The method for preparing a medicament for treating oral ulcer according to claim 6, wherein: the grinding machine comprises a base (1), a shell (2), a grinding cylinder (3), a material port (4), an end cover (5) and a grinding mechanism (7), wherein the base (1) is a circular base, the shell (2) is fixedly arranged on the upper portion of the base (1), the bottom end of the grinding cylinder (3) is of a closed structure, the grinding cylinder (3) is fixedly arranged inside the shell (2), the material port (4) is a cylindrical material port, the material port (4) is fixedly arranged at the upper end portion of the grinding cylinder (3), the inner diameter of the material port (4) is smaller than that of the grinding cylinder (3), and the end cover (5) is arranged outside the material port (4) in a covering mode;

wherein, the grinding mechanism (7) comprises a motor (701), a stirring shaft (702), a fitting seat (708), two grinding blocks (706) and two crushing blades (705), the motor (701) is fixedly arranged at the upper part of the base (1), the motor (701) is positioned in the shell (2), the stirring shaft (702) is fixedly arranged at the central position of the end wall of the bottom end of the grinding cylinder (3) through a sealed bearing (704), the bottom end of the stirring shaft (702) is fixedly connected with the rotating shaft of the motor (701) through a coupling (703), the fitting seat (708) is fixedly arranged at the upper end of the stirring shaft (702), the two grinding blocks (706) are fixedly arranged at the side part of the fitting seat (708) through a cross rod (707), the two grinding blocks (706) are symmetrically arranged, and the two crushing blades (705) are fixedly arranged at the side part of the fitting seat (708) through a connecting block (709), the two crushing blades (705) are symmetrically arranged, the connecting line between the two crushing blades (705) is perpendicular to the connecting line between the two grinding blocks (706), and the two crushing blades (705), the two grinding blocks (706) and the assembling seat (708) are all positioned inside the grinding cylinder (3).

9. The method for preparing a medicament for treating oral ulcer according to claim 8, wherein: still fixed mounting has control switch (6) on the lateral surface of shell (2), control switch (6) pass through the wire with motor (701) series connection.

10. The method for preparing a medicament for treating oral ulcer according to claim 8, wherein: the bottom of base (1) still fixed mounting have four stabilizer blades (8), four stabilizer blade (8) are the hoop and wait the angle arrangement.