CN111714625A - 杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏及其制备方法 - Google Patents
杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏及其制备方法 Download PDFInfo
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- CN111714625A CN111714625A CN202010672273.6A CN202010672273A CN111714625A CN 111714625 A CN111714625 A CN 111714625A CN 202010672273 A CN202010672273 A CN 202010672273A CN 111714625 A CN111714625 A CN 111714625A
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Abstract
本发明公开了杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏及其制备方法,包括以下质量份的原料:溶菌酶1‑1.5份、乳铁蛋白0.5‑2.5份、乳香提取物0.5‑2份、墨旱莲提取物0.5‑2份、小柴胡提取物0.5‑2份、苦参提取物0.5‑2份、板蓝根提取物0.5‑2份、连翘提取物0.5‑2份、甘草提取物0.5‑2份、百部素提取物0.5‑2份、白花蛇舌草提取物0.5‑2份、芦荟提取物0.5‑2份、菊花提取物0.5‑2份、甜叶菊提取物0.5‑2份、白芨提取物0.5‑2份和氨基己酸0.772.30份,其余为牙膏体基质。本发明提供的可杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏,口腔抑菌膏具有强效的溶菌酶和乳香油,对溶降解幽门螺旋杆菌细胞膜,降低其与口腔粘膜的附着性而起到强效杀灭幽门螺杆菌。
Description
技术领域
本发明涉及生物化工相关技术领域,具体是杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏及其制备方法。
背景技术
幽门螺杆菌是公认的致病菌,被世界卫生组织列为一级致癌物(最高级,对人类为确定致癌)。与胃病(胃炎,溃疡,胃瘤,胃癌)密切相关。一旦感染幽门螺杆菌后,胃癌得病风险增加了多倍。
如何有效的治疗或预防幽门螺杆菌,对预防和控制胃癌具有重大意义。
目前,幽门螺杆菌的防治是一个世界性难题,权威推荐疗法(抗生素+铋制剂+抑酸剂)也只有70%左右的根除率,而且随着幽门螺杆菌耐药率逐年攀升,幽门螺杆菌根除率逐年下降;并且抗生素+铋制剂+抑酸剂的疗法副作用大。
鉴于全球差不多半数人口感染幽门螺杆菌、幽门螺杆菌耐药性的攀升、幽门螺杆菌根除率的下降的现实。
目前市售常见的牙膏、口腔抑菌膏、牙粉、漱口水、牙凝胶等口腔护理类产品大多数使用合成化学药物做杀灭抗抑菌成分,长期使用合成抗菌剂对人体存在潜在的危害和安全问题,市场上虽然已有一些中草药类型的口腔护理用品,但抗抑菌效果也不够理想,更别说具有杀灭幽门螺旋杆菌的作用。因此,急需一种解决现有问题的高效防控幽门螺旋杆菌口腔抑菌膏。
发明内容
本发明的目的在于提供杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏及其制备方法,以解决上述背景技术中提出的问题。
为实现上述目的,本发明提供如下技术方案:
杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏,包括以下质量份的原料:溶菌酶1-1.5份、乳铁蛋白0.5-2.5份、乳香提取物0.5-2份、墨旱莲提取物0.5-2份、小柴胡提取物0.5-2份、苦参提取物0.5-2份、板蓝根提取物0.5-2份、连翘提取物0.5-2份、甘草提取物0.5-2份、百部素提取物0.5-2份、白花蛇舌草提取物0.5-2份、芦荟提取物0.5-2份、菊花提取物0.5-2份、甜叶菊提取物0.5-2份、白芨提取物0.5-2份和氨基己酸0.772.30份,其余为牙膏体基质。
作为本发明进一步的方案:所述杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏包括以下质量份的原料:溶菌酶1.2-1.4份、乳铁蛋白0.8-1.6份、乳香提取物0.8-1.6份、墨旱莲提取物0.8-1.6份、小柴胡提取物0.8-1.6份、苦参提取物0.8-1.6份、板蓝根提取物0.8-1.6份、连翘提取物0.8-1.6份、甘草提取物0.8-1.6份、百部素提取物0.8-1.6份、白花蛇舌草提取物0.8-1.6份、芦荟提取物0.8-1.6份、菊花提取物0.8-1.6份、甜叶菊提取物0.8-1.6份、白芨提取物0.8-1.6份和氨基己酸1.2-2.1份,其余为牙膏体基质。
作为本发明进一步的方案:所述杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏包括以下质量份的原料:溶菌酶1.3份、乳铁蛋白1.2份、乳香提取物1.2份、墨旱莲提取物1.2份、小柴胡提取物1.2份、苦参提取物1.2份、板蓝根提取物1.2份、连翘提取物1.2份、甘草提取物1.2份、百部素提取物1.2份、白花蛇舌草提取物1.2份、芦荟提取物1.2份、菊花提取物1.2份、甜叶菊提取物1.2份、白芨提取物1.2份和氨基己酸1.8份,其余为牙膏体基质。
作为本发明进一步的方案:所述牙膏体基质包括以下质量份的原料:摩擦剂5-25份、保湿剂10-30份、发泡剂1.5-3份、增稠剂0.3-15份、粘合剂0.3-15份、甜味剂0.5-2份、去离子水50-60份。
所述牙膏体基质包括以下质量份的原料:摩擦剂10-20份、保湿剂15-25份、发泡剂1.7-2.6份、增稠剂6-12份、粘合剂6-12份、甜味剂1-1.7份、去离子水52-57份。
所述牙膏体基质包括以下质量份的原料:摩擦剂15份、保湿剂20份、发泡剂2.3份、增稠剂9份、粘合剂9份、甜味剂1.5份、去离子水55份。
杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏的制备方法,包括以下步骤:
S1、将溶菌酶、乳铁蛋白、乳香提取物、墨旱莲提取物、小柴胡提取物、苦参提取物、板蓝根提取物、连翘提取物、甘草提取物、百部素提取物、白花蛇舌草提取物、芦荟提取物、菊花提取物、甜叶菊提取物、白芨提取物和氨基己酸加入到搅拌罐中进行搅拌得到混合液;
S2、将上述混合液加入到真空制膏机中,随后加入牙膏体基质进行搅拌、真空脱气、灌装。
作为本发明进一步的方案:所述乳香提取物的制备方法,包括以下步骤:
S11、将乳香树脂依次经过干燥、冷冻、粉碎和加热后获得乳香液;将乳香树树脂在-12℃条件下冷冻6h后粉碎,并慢速加热至75℃得乳香液;
S12、将乳香液加入1:10蒸馏水进行搅拌,搅拌后采用回流提取法加热,然后经过二次回流滤渣,最后浓缩获得乳香提取物。
与现有技术相比,本发明的有益效果是:本发明提供的可杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏,口腔抑菌膏具有强效的溶菌酶和乳香油,对溶降解幽门螺旋杆菌细胞膜,降低其与口腔粘膜的附着性而起到强效杀灭幽门螺杆菌。
2、长效的乳铁蛋白可促进双歧杆菌增生,双歧杆菌是革兰氏阳性菌能有效抑制幽门螺旋杆菌的生长,通过残留在牙齿间的乳铁蛋白,不断促进益生菌双歧杆菌的生长从而达到保持口腔内强效与长效相结合的口腔内幽门螺旋杆菌杀灭效果。
3、本发明所述的可杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏,二种功效抑制幽门螺旋杆菌细胞作用,起到相互强效与长效相结合,能有效预防幽门螺旋杆菌滋生,可强效杀灭和长效抑制口腔幽门螺杆菌,效去除口腔异味、牙菌斑、牙结石、改善牙龈肿痛出血、口腔溃疡、预防牙周炎且能强健牙质,保持口腔的卫生健康,起到杜绝幽门螺旋杆菌进入胃部的防火墙。
具体实施方式
下面将结合本发明实施例,对本发明实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本发明一部分实施例,而不是全部的实施例。基于本发明中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。
实施例1
本发明实施例中,杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏,包括以下质量份的原料:溶菌酶1份、乳铁蛋白0.5份、乳香提取物0.5份、墨旱莲提取物0.5份、小柴胡提取物0.5份、苦参提取物0.5份、板蓝根提取物0.5份、连翘提取物0.5份、甘草提取物0.5份、百部素提取物0.5份、白花蛇舌草提取物0.5份、芦荟提取物0.5份、菊花提取物0.5份、甜叶菊提取物0.5份、白芨提取物0.5份和氨基己酸0.77份,其余为牙膏体基质。
在本发明的实施例中,所述牙膏体基质包括以下质量份的原料:摩擦剂5-25份、保湿剂10份、发泡剂1.5份、增稠剂0.3份、粘合剂0.3份、甜味剂0.5份、去离子水50份。
在本发明实施例中,所述摩擦剂为二氧化硅或/和磷酸氢钙;所述发泡剂为十二烷基硫酯钠或/和椰油酰基谷氨酸钠;所述保湿剂为木糖醇或/和甘油及山梨糖醇;所述增稠剂为黄原胶或/和海藻酸钠;所述粘合剂为羧甲基纤维。
所述杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏的制备方法,具体制备步骤为:
S1、将溶菌酶、乳铁蛋白、乳香提取物、墨旱莲提取物、小柴胡提取物、苦参提取物、板蓝根提取物、连翘提取物、甘草提取物、百部素提取物、白花蛇舌草提取物、芦荟提取物、菊花提取物、甜叶菊提取物、白芨提取物和氨基己酸加入到搅拌罐中进行搅拌得到混合液;
S2、将上述混合液加入到真空制膏机中,随后加入牙膏体基质进行搅拌、真空脱气、灌装。
在本发明的实施例中,所述乳香提取物的制备方法,包括以下步骤:
S11、将乳香树脂依次经过干燥、冷冻、粉碎和加热后获得乳香液;将乳香树树脂在-12℃条件下冷冻6h后粉碎,并慢速加热至75℃得乳香液;
S12、将乳香液加入1:10蒸馏水进行搅拌,搅拌后采用回流提取法加热,然后经过二次回流滤渣,最后浓缩获得乳香提取物。
实施例2
本发明实施例中,杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏,包括以下质量份的原料:溶菌酶1.2份、乳铁蛋白0.8份、乳香提取物0.8份、墨旱莲提取物0.8份、小柴胡提取物0.8份、苦参提取物0.8份、板蓝根提取物0.8份、连翘提取物0.8份、甘草提取物0.8份、百部素提取物0.8份、白花蛇舌草提取物0.8份、芦荟提取物0.8份、菊花提取物0.8份、甜叶菊提取物0.8份、白芨提取物0.8份和氨基己酸1.2份,其余为牙膏体基质。
在本发明的实施例中,所述牙膏体基质包括以下质量份的原料:摩擦剂10份、保湿剂15份、发泡剂1.7份、增稠剂6份、粘合剂6份、甜味剂1份、去离子水52份。
在本发明实施例中,所述摩擦剂为二氧化硅或/和磷酸氢钙;所述发泡剂为十二烷基硫酯钠或/和椰油酰基谷氨酸钠;所述保湿剂为木糖醇或/和甘油及山梨糖醇;所述增稠剂为黄原胶或/和海藻酸钠;所述粘合剂为羧甲基纤维。
所述杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏的制备方法,具体制备步骤为:
S1、将溶菌酶、乳铁蛋白、乳香提取物、墨旱莲提取物、小柴胡提取物、苦参提取物、板蓝根提取物、连翘提取物、甘草提取物、百部素提取物、白花蛇舌草提取物、芦荟提取物、菊花提取物、甜叶菊提取物、白芨提取物和氨基己酸加入到搅拌罐中进行搅拌得到混合液;
S2、将上述混合液加入到真空制膏机中,随后加入牙膏体基质进行搅拌、真空脱气、灌装。
在本发明的实施例中,所述乳香提取物的制备方法,包括以下步骤:
S11、将乳香树脂依次经过干燥、冷冻、粉碎和加热后获得乳香液;将乳香树树脂在-12℃条件下冷冻6h后粉碎,并慢速加热至75℃得乳香液;
S12、将乳香液加入1:10蒸馏水进行搅拌,搅拌后采用回流提取法加热,然后经过二次回流滤渣,最后浓缩获得乳香提取物。
实施例3
本发明实施例中,杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏,包括以下质量份的原料:溶菌酶1.3份、乳铁蛋白1.2份、乳香提取物1.2份、墨旱莲提取物1.2份、小柴胡提取物1.2份、苦参提取物1.2份、板蓝根提取物1.2份、连翘提取物1.2份、甘草提取物1.2份、百部素提取物1.2份、白花蛇舌草提取物1.2份、芦荟提取物1.2份、菊花提取物1.2份、甜叶菊提取物1.2份、白芨提取物1.2份和氨基己酸1.8份,其余为牙膏体基质。
在本发明的实施例中,所述牙膏体基质包括以下质量份的原料:摩擦剂15份、保湿剂20份、发泡剂2.3份、增稠剂9份、粘合剂9份、甜味剂1.5份、去离子水55份。
在本发明实施例中,所述摩擦剂为二氧化硅或/和磷酸氢钙;所述发泡剂为十二烷基硫酯钠或/和椰油酰基谷氨酸钠;所述保湿剂为木糖醇或/和甘油及山梨糖醇;所述增稠剂为黄原胶或/和海藻酸钠;所述粘合剂为羧甲基纤维。
所述杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏的制备方法,具体制备步骤为:
S1、将溶菌酶、乳铁蛋白、乳香提取物、墨旱莲提取物、小柴胡提取物、苦参提取物、板蓝根提取物、连翘提取物、甘草提取物、百部素提取物、白花蛇舌草提取物、芦荟提取物、菊花提取物、甜叶菊提取物、白芨提取物和氨基己酸加入到搅拌罐中进行搅拌得到混合液;
S2、将上述混合液加入到真空制膏机中,随后加入牙膏体基质进行搅拌、真空脱气、灌装。
在本发明的实施例中,所述乳香提取物的制备方法,包括以下步骤:
S11、将乳香树脂依次经过干燥、冷冻、粉碎和加热后获得乳香液;将乳香树树脂在-12℃条件下冷冻6h后粉碎,并慢速加热至75℃得乳香液;
S12、将乳香液加入1:10蒸馏水进行搅拌,搅拌后采用回流提取法加热,然后经过二次回流滤渣,最后浓缩获得乳香提取物。
实施例4
本发明实施例中,杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏,包括以下质量份的原料:溶菌酶1.4份、乳铁蛋白1.6份、乳香提取物1.6份、墨旱莲提取物1.6份、小柴胡提取物1.6份、苦参提取物1.6份、板蓝根提取物1.6份、连翘提取物1.6份、甘草提取物1.6份、百部素提取物1.6份、白花蛇舌草提取物1.6份、芦荟提取物1.6份、菊花提取物1.6份、甜叶菊提取物1.6份、白芨提取物1.6份和氨基己酸2.1份,其余为牙膏体基质。
在本发明的实施例中,所述牙膏体基质包括以下质量份的原料:摩擦剂20份、保湿剂25份、发泡剂2.6份、增稠剂12份、粘合剂12份、甜味剂1.7份、去离子水57份。
在本发明实施例中,所述摩擦剂为二氧化硅或/和磷酸氢钙;所述发泡剂为十二烷基硫酯钠或/和椰油酰基谷氨酸钠;所述保湿剂为木糖醇或/和甘油及山梨糖醇;所述增稠剂为黄原胶或/和海藻酸钠;所述粘合剂为羧甲基纤维。
所述杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏的制备方法,具体制备步骤为:
S1、将溶菌酶、乳铁蛋白、乳香提取物、墨旱莲提取物、小柴胡提取物、苦参提取物、板蓝根提取物、连翘提取物、甘草提取物、百部素提取物、白花蛇舌草提取物、芦荟提取物、菊花提取物、甜叶菊提取物、白芨提取物和氨基己酸加入到搅拌罐中进行搅拌得到混合液;
S2、将上述混合液加入到真空制膏机中,随后加入牙膏体基质进行搅拌、真空脱气、灌装。
在本发明的实施例中,所述乳香提取物的制备方法,包括以下步骤:
S11、将乳香树脂依次经过干燥、冷冻、粉碎和加热后获得乳香液;将乳香树树脂在-12℃条件下冷冻6h后粉碎,并慢速加热至75℃得乳香液;
S12、将乳香液加入1:10蒸馏水进行搅拌,搅拌后采用回流提取法加热,然后经过二次回流滤渣,最后浓缩获得乳香提取物。
实施例5
本发明实施例中,杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏,包括以下质量份的原料:溶菌酶1.5份、乳铁蛋白2.5份、乳香提取物2份、墨旱莲提取物2份、小柴胡提取物2份、苦参提取物2份、板蓝根提取物2份、连翘提取物2份、甘草提取物2份、百部素提取物2份、白花蛇舌草提取物2份、芦荟提取物2份、菊花提取物2份、甜叶菊提取物2份、白芨提取物2份和氨基己酸2.30份,其余为牙膏体基质。
在本发明的实施例中,所述牙膏体基质包括以下质量份的原料:摩擦剂25份、保湿剂30份、发泡剂3份、增稠剂15份、粘合剂15份、甜味剂2份、去离子水60份。
在本发明实施例中,所述摩擦剂为二氧化硅或/和磷酸氢钙;所述发泡剂为十二烷基硫酯钠或/和椰油酰基谷氨酸钠;所述保湿剂为木糖醇或/和甘油及山梨糖醇;所述增稠剂为黄原胶或/和海藻酸钠;所述粘合剂为羧甲基纤维。
所述杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏的制备方法,具体制备步骤为:
S1、将溶菌酶、乳铁蛋白、乳香提取物、墨旱莲提取物、小柴胡提取物、苦参提取物、板蓝根提取物、连翘提取物、甘草提取物、百部素提取物、白花蛇舌草提取物、芦荟提取物、菊花提取物、甜叶菊提取物、白芨提取物和氨基己酸加入到搅拌罐中进行搅拌得到混合液;
S2、将上述混合液加入到真空制膏机中,随后加入牙膏体基质进行搅拌、真空脱气、灌装。
在本发明的实施例中,所述乳香提取物的制备方法,包括以下步骤:
S11、将乳香树脂依次经过干燥、冷冻、粉碎和加热后获得乳香液;将乳香树树脂在-12℃条件下冷冻6h后粉碎,并慢速加热至75℃得乳香液;
S12、将乳香液加入1:10蒸馏水进行搅拌,搅拌后采用回流提取法加热,然后经过二次回流滤渣,最后浓缩获得乳香提取物。
对于本领域技术人员而言,显然本发明不限于上述示范性实施例的细节,而且在不背离本发明的精神或基本特征的情况下,能够以其他的具体形式实现本发明。因此,无论从哪一点来看,均应将实施例看作是示范性的,而且是非限制性的,本发明的范围由所附权利要求而不是上述说明限定,因此旨在将落在权利要求的等同要件的含义和范围内的所有变化囊括在本发明内。
此外,应当理解,虽然本说明书按照实施方式加以描述,但并非每个实施方式仅包含一个独立的技术方案,说明书的这种叙述方式仅仅是为清楚起见,本领域技术人员应当将说明书作为一个整体,各实施例中的技术方案也可以经适当组合,形成本领域技术人员可以理解的其他实施方式。
Claims (8)
1.杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏,其特征在于,包括以下质量份的原料:溶菌酶1-1.5份、乳铁蛋白0.5-2.5份、乳香提取物0.5-2份、墨旱莲提取物0.5-2份、小柴胡提取物0.5-2份、苦参提取物0.5-2份、板蓝根提取物0.5-2份、连翘提取物0.5-2份、甘草提取物0.5-2份、百部素提取物0.5-2份、白花蛇舌草提取物0.5-2份、芦荟提取物0.5-2份、菊花提取物0.5-2份、甜叶菊提取物0.5-2份、白芨提取物0.5-2份和氨基己酸0.772.30份,其余为牙膏体基质。
2.根据权利要求1所述的杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏,其特征在于,所述杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏包括以下质量份的原料:溶菌酶1.2-1.4份、乳铁蛋白0.8-1.6份、乳香提取物0.8-1.6份、墨旱莲提取物0.8-1.6份、小柴胡提取物0.8-1.6份、苦参提取物0.8-1.6份、板蓝根提取物0.8-1.6份、连翘提取物0.8-1.6份、甘草提取物0.8-1.6份、百部素提取物0.8-1.6份、白花蛇舌草提取物0.8-1.6份、芦荟提取物0.8-1.6份、菊花提取物0.8-1.6份、甜叶菊提取物0.8-1.6份、白芨提取物0.8-1.6份和氨基己酸1.2-2.1份,其余为牙膏体基质。
3.根据权利要求2所述的杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏,其特征在于,所述杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏包括以下质量份的原料:溶菌酶1.3份、乳铁蛋白1.2份、乳香提取物1.2份、墨旱莲提取物1.2份、小柴胡提取物1.2份、苦参提取物1.2份、板蓝根提取物1.2份、连翘提取物1.2份、甘草提取物1.2份、百部素提取物1.2份、白花蛇舌草提取物1.2份、芦荟提取物1.2份、菊花提取物1.2份、甜叶菊提取物1.2份、白芨提取物1.2份和氨基己酸1.8份,其余为牙膏体基质。
4.根据权利要求1-3任意一项所述的杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏,其特征在于,所述牙膏体基质包括以下质量份的原料:摩擦剂5-25份、保湿剂10-30份、发泡剂1.5-3份、增稠剂0.3-15份、粘合剂0.3-15份、甜味剂0.5-2份、去离子水50-60份。
5.根据权利要求4所述的杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏,其特征在于,所述牙膏体基质包括以下质量份的原料:摩擦剂10-20份、保湿剂15-25份、发泡剂1.7-2.6份、增稠剂6-12份、粘合剂6-12份、甜味剂1-1.7份、去离子水52-57份。
6.根据权利要求5所述的杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏,其特征在于,所述牙膏体基质包括以下质量份的原料:摩擦剂15份、保湿剂20份、发泡剂2.3份、增稠剂9份、粘合剂9份、甜味剂1.5份、去离子水55份。
7.如权利要求1-6任意一项所述杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏的制备方法,其特征在于,包括以下步骤:
S1、将溶菌酶、乳铁蛋白、乳香提取物、墨旱莲提取物、小柴胡提取物、苦参提取物、板蓝根提取物、连翘提取物、甘草提取物、百部素提取物、白花蛇舌草提取物、芦荟提取物、菊花提取物、甜叶菊提取物、白芨提取物和氨基己酸加入到搅拌罐中进行搅拌得到混合液;
S2、将上述混合液加入到真空制膏机中,随后加入牙膏体基质进行搅拌、真空脱气、灌装。
8.根据权利要求7所述杀灭或抑制口腔内幽门螺旋杆菌的抑菌膏的制备方法,其特征在于,所述乳香提取物的制备方法,包括以下步骤:
S11、将乳香树脂依次经过干燥、冷冻、粉碎和加热后获得乳香液;将乳香树树脂在-12℃条件下冷冻6h后粉碎,并慢速加热至75℃得乳香液;
S12、将乳香液加入1:10蒸馏水进行搅拌,搅拌后采用回流提取法加热,然后经过二次回流滤渣,最后浓缩获得乳香提取物。
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王厚伟等: "基于计算机编程的抗菌中药性效分析", 《辽宁中医杂志》 * |
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CN112316123A (zh) * | 2020-12-03 | 2021-02-05 | 滁州向日葵药业有限公司 | 一种抗幽门螺杆菌感染的中药组合物及其制备方法与应用 |
CN112545978A (zh) * | 2020-12-15 | 2021-03-26 | 上海利康消毒高科技有限公司 | 具有持效抗幽门螺杆菌作用的口腔护理凝胶及其制备方法 |
CN112494401A (zh) * | 2020-12-17 | 2021-03-16 | 江门市金本士贸易有限公司 | 一种祛黄洁白抗幽门螺旋杆菌的抑菌中药牙膏 |
CN116076736A (zh) * | 2023-04-07 | 2023-05-09 | 北京东方红航天生物技术股份有限公司 | 一种抗幽养胃组合物及其应用 |
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