CN111714602A - Chinese herbal medicine for adjuvant therapy of insomnia and preparation method thereof - Google Patents
Chinese herbal medicine for adjuvant therapy of insomnia and preparation method thereof Download PDFInfo
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- CN111714602A CN111714602A CN201910493830.5A CN201910493830A CN111714602A CN 111714602 A CN111714602 A CN 111714602A CN 201910493830 A CN201910493830 A CN 201910493830A CN 111714602 A CN111714602 A CN 111714602A
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/725—Ziziphus, e.g. jujube
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2236/30—Extraction of the material
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
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- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Anesthesiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
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Abstract
The invention discloses a Chinese herbal medicine for adjuvant therapy of insomnia and a preparation method thereof, belonging to the field of Chinese herbal medicine preparation. The Chinese herbal medicine for adjuvant therapy of insomnia is characterized by comprising the following raw materials in parts by weight: 27-42 parts of pseudo-ginseng stem leaves, 13-27 parts of poria cocos, 8-22 parts of semen cassiae, 3-17 parts of semen euryales, 3-17 parts of fructus alpiniae oxyphyllae and 3-17 parts of spina date seeds, and a Chinese herbal medicine for assisting in treating insomnia and a preparation method thereof, and is characterized in that the preparation method comprises the following steps: the method comprises the following steps: processing the cassia seeds in parts by weight at the temperature of 60-100 ℃, and frying the cassia seeds until the crackling sound of the cassia seeds in the whole pot begins to reduce on the principle of quick frying, wherein the second step is as follows: pouring the stem leaves of the pseudo-ginseng into a certain container, smashing the stem leaves of the pseudo-ginseng into coarse powder for later use, adding 10 times of 41-65% ethanol (V/W), carrying out primary heating reflux extraction for 1-3 hours to obtain an extracting solution a, and carrying out secondary heating reflux extraction for 1 hour; the traditional Chinese medicine preparation for treating insomnia provided by the invention supplements each other, has simple components, is safe and has no toxic or side effect.
Description
Technical Field
The invention relates to the technical field of Chinese herbal medicine preparation, in particular to a Chinese herbal medicine for adjuvant therapy of insomnia and a preparation method thereof.
Background
Insomnia refers to the failure to fall asleep or to maintain a state of sleep, resulting in insufficient sleep. Also called as sleep-in and sleep-maintaining disorder, it is caused by various reasons such as difficulty in falling asleep, too short sleep depth or frequency, early awakening, insufficient sleep time or poor quality. The roll can not fall asleep or can not fall asleep after waking up in the middle of the night. It is a common disease in which a patient does not meet sleep time or quality and affects daytime social functioning.
Insomnia can be classified into primary insomnia and secondary insomnia according to the etiology. Primary insomnia usually lacks a definite cause or remains insomnia symptoms after excluding causes that may cause insomnia, mainly including psychophysiological insomnia, idiopathic insomnia and subjective insomnia of 3 types. The diagnosis of primary insomnia lacks specific indexes, and is mainly an exclusionary diagnosis. Secondary insomnia includes insomnia due to physical diseases, mental disorders, drug abuse, etc., and insomnia associated with sleep disordered breathing, sleep movement disorder, etc.
The conventional methods for treating insomnia can be divided into several aspects such as physical therapy, pharmacotherapy, psychotherapy and the like, and the general treatment principle and purpose are to improve the sleep quality and increase the sleep time; improving the life quality of patients and recovering social functions; reducing or eliminating the risk of or co-morbidities with somatic diseases associated with insomnia; avoiding negative effects brought by drug intervention and the like. However, most of the existing pharmacotherapy has more complex components and is easy to generate toxic and side effects.
Disclosure of Invention
The invention aims to solve the problems that most of the components are complex and toxic and side effects are easy to generate in the traditional Chinese medicine therapy in the prior art, and provides a Chinese herbal medicine for adjuvant therapy of insomnia and a preparation method thereof.
In order to achieve the purpose, the invention adopts the following technical scheme:
the Chinese herbal medicine for adjuvant therapy of insomnia is characterized by comprising the following raw materials in parts by weight: 27-42 parts of pseudo-ginseng stem leaves, 13-27 parts of poria cocos, 8-22 parts of semen cassiae, 3-17 parts of semen euryales, 3-17 parts of fructus alpiniae oxyphyllae and 3-17 parts of spina date seeds.
Preferably, the Chinese herbal medicine for adjuvant therapy of insomnia is characterized by comprising the following raw materials in parts by weight: 35 parts of pseudo-ginseng stem leaves, 20 parts of poria cocos, 15 parts of semen cassiae, 10 parts of semen euryales, 10 parts of fructus alpiniae oxyphyllae and 10 parts of spina date seeds.
Preferably, the Chinese herbal medicine for adjuvant therapy of insomnia and the preparation method thereof are characterized in that the preparation method comprises the following steps:
the method comprises the following steps: processing the cassia seeds in parts by weight at the temperature of 60-100 ℃, and stir-frying until the crackling sound of the cassia seeds in the whole pot begins to reduce on the principle of stir-frying.
Step two: pouring the stem leaves of the pseudo-ginseng into a certain container, smashing the stem leaves of the pseudo-ginseng into coarse powder for later use, adding 10 times of 41-65% ethanol (V/W), carrying out primary heating reflux extraction for 1-3 hours to obtain an extracting solution a, carrying out secondary heating reflux extraction for 1 hour to obtain an extracting solution b, combining the extracting solution a and the extracting solution b, and concentrating the obtained mixture to obtain the pseudo-ginseng crude extract with the amount of about 0.5 time of the raw materials.
Step three: weighing Poria, semen euryales, fructus Alpinae Oxyphyllae, and semen Ziziphi Spinosae at a given ratio, pouring the raw materials into a container, pouring the parched semen Cassiae into the container, adding 10 times of purified water, boiling with strong fire, decocting with slow fire for 0.5-5 hr, and filtering to obtain medicinal liquid c.
Step four: adding 6 times of purified water into the residue, boiling, decocting with slow fire for 0.5-5 hr, and filtering to obtain medicinal liquid d.
Step five: and mixing the liquid medicine c and the liquid medicine d, and filtering the mixture through a 50-mesh stainless steel screen to obtain liquid medicine e.
Step six: mixing the liquid medicine e and the pseudo-ginseng crude extract uniformly, concentrating in a concentration tank to a relative specific gravity of 1.10-1.30g/ml, and filtering with a stainless steel filter screen of 200 meshes to obtain a liquid medicine f.
Step seven: adding adjuvants into the liquid medicine f, mixing and stirring for 15 min to obtain a mixture g, and vacuum packaging under aseptic condition.
Preferably, the temperature in the first step is 80 ℃.
Preferably, the ethanol concentration in the second step is 45%.
Preferably, in the second step, the primary extraction is performed for 2 hours.
Preferably, in the third step and the fourth step, the mixture is cooked for 2 hours by using a slow fire.
Preferably, the liquid medicine c in the sixth step is concentrated to the relative specific gravity of 1.180-1.200 g/ml.
Preferably, the seven auxiliary materials in the step are one or more of gamma-aminobutyric acid, pectin, xylitol and essence.
Preferably, the mixture g obtained in the seventh step can be taken with water, can be soaked in water, and can be stuck to the navel by using an adhesive tape.
Compared with the prior art, the invention provides the Chinese herbal medicine for adjuvant therapy of insomnia and the preparation method thereof, and the Chinese herbal medicine has the following beneficial effects:
1. the Chinese herbal medicine for adjuvant treatment of insomnia is recorded in the golden lack essentials through Zhang Zhongjing: insomnia is caused by liver blood deficiency and yin deficiency with internal heat, and is indicated for tonifying blood and regulating liver, nourishing heart and tranquilizing mind, clearing heat and relieving restlessness, so as to relieve symptoms of liver blood deficiency, heart-mind tranquilization and restlessness due to deficiency. According to the traditional Chinese medicine analysis, liver storing soul, internal fire, liver blood deficiency and heart disturbing cause uneasiness, so that vexation, insomnia and palpitation occur; dizziness due to disturbance of the deficient yang, and vertigo; night sweating due to deficiency heat forcing the body fluids to discharge; a dry throat and mouth with a thready, wiry or rapid pulse is the condition of yin deficiency with internal heat. Therefore, the invention uses the stem and leaf of the panax notoginseng as monarch drug for tranquilization and nourishing the heart and improving the blood supply of the brain; the tuckahoe, the heart calming and the mind tranquilizing, and the cassia seed, the bitter cold and moist, are used as ministerial drugs; the spina date seed is used for greatly tonifying heart and spleen and regulating qi activity, is matched with monarch drug, is used together with pungent powder for assisting each other in sour recovery and nourishing blood, regulating liver and soothing nerves; the raw sharpleaf galangal fruit is used for regulating the middle warmer and relieving urgency, harmonizing the effects of the raw sharpleaf galangal fruit, tonifying spleen and regulating the middle warmer when being matched with tuckahoe, and nourishing liver yin when being combined with spina date seed acid and sweet and combined, and is used as a guiding drug, so that the insomnia condition can be easily improved, and the sharpleaf galangal fruit and wild jujube seed tea is safe and has no toxic or side effect.
2. The Chinese herbal medicine for assisting in treating insomnia can effectively calm and calm nerves by various components such as flavonoid glycoside, triterpene, saponin, organic acid and the like contained in the spina date seed, has obvious curative effect on insomnia patients, the spina date seed is mainly used for obviously improving sleep condition by regulating qi and blood functions of internal organs of a human body, and rarely generates toxic and side effects, and the spina date seed is mainly used for influencing the deep sleep stage of slow wave sleep, so that the average time of deep sleep is prolonged, the attack frequency is increased, and the treatment purpose is easily achieved.
3. This chinese herbal medicine of adjunctie therapy insomnia through providing multiple application method, and the user easily selects a mode that is suitable oneself, has improved autonomic selectivity, and to the user who is unscrupulous psychology to the medicine, can directly apply in navel eye department, lets the medicine carry out all-round absorption.
The parts which are not involved in the device are the same as or can be realized by adopting the prior art, and the traditional Chinese medicine preparation for treating insomnia provided by the invention supplements each other, has simple components, is safe and has no toxic or side effect.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments.
Example 1:
the Chinese herbal medicine for adjuvant therapy of insomnia is characterized by comprising the following raw materials in parts by weight: 27 parts of pseudo-ginseng stem and leaf, 13 parts of poria cocos, 8 parts of semen cassiae, 3 parts of semen euryales, 3 parts of fructus alpiniae oxyphyllae and 3 parts of spina date seeds.
A Chinese herbal medicine for adjuvant therapy of insomnia and a preparation method thereof are characterized in that the preparation method comprises the following steps:
the method comprises the following steps: processing the cassia seeds in parts by weight at 80 ℃, and stir-frying until the crackle of the cassia seeds in the whole pot begins to be reduced on the principle of stir-frying.
Step two: pouring the stem leaves of the pseudo-ginseng into a certain container, smashing the stem leaves of the pseudo-ginseng into coarse powder for later use, adding 10 times of 45% ethanol (V/W), carrying out primary heating reflux extraction for 2 hours to obtain an extracting solution a, carrying out secondary heating reflux extraction for 1 hour to obtain an extracting solution b, combining the extracting solution a and the extracting solution b, and concentrating the obtained mixture to obtain the pseudo-ginseng crude extract with the amount of about 0.5 time of the raw materials.
Step three: weighing Poria, semen euryales, fructus Alpinae Oxyphyllae, and semen Ziziphi Spinosae at a given ratio, pouring the raw materials into a container, pouring the parched semen Cassiae into the container, adding 10 times of purified water, boiling with strong fire, decocting with slow fire for 2 hr, and filtering to obtain medicinal liquid c.
Step four: adding 6 times of purified water into the residue, boiling, decocting with slow fire for 2 hr, and filtering to obtain medicinal liquid d.
Step five: and mixing the liquid medicine c and the liquid medicine d, and filtering the mixture through a 50-mesh stainless steel screen to obtain liquid medicine e.
Step six: mixing the liquid medicine e and the pseudo-ginseng crude extract uniformly, concentrating in a concentration tank to the relative specific gravity of 1.180-1.200g/ml, and filtering by using a stainless steel filter screen of 200 meshes to obtain liquid medicine f.
Step seven: adding one or more of gamma-aminobutyric acid, pectin, xylitol and essence into the liquid medicine f, mixing and stirring for 15 minutes to obtain a mixture g, and carrying out vacuum packaging under the aseptic condition to obtain the product.
Example 2:
the Chinese herbal medicine for adjuvant therapy of insomnia is characterized by comprising the following raw materials in parts by weight: 42 parts of pseudo-ginseng stem leaves, 27 parts of poria cocos, 22 parts of semen cassiae, 17 parts of semen euryales, 17 parts of fructus alpiniae oxyphyllae and 17 parts of spina date seeds.
A Chinese herbal medicine for adjuvant therapy of insomnia and a preparation method thereof are characterized in that the preparation method comprises the following steps:
the method comprises the following steps: processing the cassia seeds in parts by weight at 80 ℃, and stir-frying until the crackle of the cassia seeds in the whole pot begins to be reduced on the principle of stir-frying.
Step two: pouring the stem leaves of the pseudo-ginseng into a certain container, smashing the stem leaves of the pseudo-ginseng into coarse powder for later use, adding 10 times of 45% ethanol (V/W), carrying out primary heating reflux extraction for 2 hours to obtain an extracting solution a, carrying out secondary heating reflux extraction for 1 hour to obtain an extracting solution b, combining the extracting solution a and the extracting solution b, and concentrating the obtained mixture to obtain the pseudo-ginseng crude extract with the amount of about 0.5 time of the raw materials.
Step three: weighing Poria, semen euryales, fructus Alpinae Oxyphyllae, and semen Ziziphi Spinosae at a given ratio, pouring the raw materials into a container, pouring the parched semen Cassiae into the container, adding 10 times of purified water, boiling with strong fire, decocting with slow fire for 2 hr, and filtering to obtain medicinal liquid c.
Step four: adding 6 times of purified water into the residue, boiling, decocting with slow fire for 2 hr, and filtering to obtain medicinal liquid d.
Step five: and mixing the liquid medicine c and the liquid medicine d, and filtering the mixture through a 50-mesh stainless steel screen to obtain liquid medicine e.
Step six: mixing the liquid medicine e and the pseudo-ginseng crude extract uniformly, concentrating in a concentration tank to the relative specific gravity of 1.180-1.200g/ml, and filtering by using a stainless steel filter screen of 200 meshes to obtain liquid medicine f.
Step seven: adding one or more of gamma-aminobutyric acid, pectin, xylitol and essence into the liquid medicine f, mixing and stirring for 15 minutes to obtain a mixture g, and carrying out vacuum packaging under the aseptic condition to obtain the product.
Example 3:
the Chinese herbal medicine for adjuvant therapy of insomnia is characterized by comprising the following raw materials in parts by weight: 35 parts of pseudo-ginseng stem leaves, 20 parts of poria cocos, 15 parts of semen cassiae, 10 parts of semen euryales, 10 parts of fructus alpiniae oxyphyllae and 10 parts of spina date seeds.
A Chinese herbal medicine for adjuvant therapy of insomnia and a preparation method thereof are characterized in that the preparation method comprises the following steps:
the method comprises the following steps: processing the cassia seeds in parts by weight at 80 ℃, and stir-frying until the crackle of the cassia seeds in the whole pot begins to be reduced on the principle of stir-frying.
Step two: pouring the stem leaves of the pseudo-ginseng into a certain container, smashing the stem leaves of the pseudo-ginseng into coarse powder for later use, adding 10 times of 45% ethanol (V/W), carrying out primary heating reflux extraction for 2 hours to obtain an extracting solution a, carrying out secondary heating reflux extraction for 1 hour to obtain an extracting solution b, combining the extracting solution a and the extracting solution b, and concentrating the obtained mixture to obtain the pseudo-ginseng crude extract with the amount of about 0.5 time of the raw materials.
Step three: weighing Poria, semen euryales, fructus Alpinae Oxyphyllae, and semen Ziziphi Spinosae at a given ratio, pouring the raw materials into a container, pouring the parched semen Cassiae into the container, adding 10 times of purified water, boiling with strong fire, decocting with slow fire for 2 hr, and filtering to obtain medicinal liquid c.
Step four: adding 6 times of purified water into the residue, boiling, decocting with slow fire for 2 hr, and filtering to obtain medicinal liquid d.
Step five: and mixing the liquid medicine c and the liquid medicine d, and filtering the mixture through a 50-mesh stainless steel screen to obtain liquid medicine e.
Step six: mixing the liquid medicine e and the pseudo-ginseng crude extract uniformly, concentrating in a concentration tank to the relative specific gravity of 1.180-1.200g/ml, and filtering by using a stainless steel filter screen of 200 meshes to obtain liquid medicine f.
Step seven: adding one or more of gamma-aminobutyric acid, pectin, xylitol and essence into the liquid medicine f, mixing and stirring for 15 minutes to obtain a mixture g, and carrying out vacuum packaging under the aseptic condition to obtain the product.
The stem and leaf of pseudo-ginseng can promote the blood circulation of our body, from this point of view, can help us to improve the blood supply situation of the brain, so often eat stem and leaf of pseudo-ginseng can play the effects of calming the nerves and nourishing the heart, therefore have very good effects on improving the quality of sleep, because stem and leaf of pseudo-ginseng can also play the effects of easing pain, there are many people because some disease problems appear the body pain, cause the quality of sleep to be poor, at this moment we can also eat some stem and leaf of pseudo-ginseng to improve the pain, and the symptom of malaise of the body, it is easy to improve the quality of sleep, help us to fall asleep better; the function of the tuckahoe is as follows: calming the heart, tranquilizing the mind, removing toxic materials, and resisting cancer; mild property, eliminating dampness without damaging healthy qi; the proper amount of the health food can be taken as a good nursing product in spring and summer in wet seasons; can be used for treating dysuria, edema, fullness, phlegm retention, cough, vomiting, diarrhea, spermatorrhea, stranguria with turbid urine, palpitation, and amnesia; the contained pachymic acid has effects of enhancing immunity, resisting tumor, tranquilizing mind, and lowering blood sugar; can relax smooth muscle of digestive tract, inhibit gastric acid secretion, prevent hepatocyte necrosis, and resist bacteria. The cassia seeds are slightly cold in nature and easy to cause diarrhea and the like, and should be drunk after being processed, the processing of the cassia seeds adopts the principle of stir-frying until a lot of continuous crackles (the sound of stir-frying the episperms) are heard, the cassia seeds are fried when the medicine effect is best, and if the stomach and intestine is poor and the cassia seeds are easy to diarrhea, the cassia seeds can be fried again until the crackles of the whole pot of cassia seeds begin to be reduced; the gorgon euryale seed is also called a chicken head seed, is a dry mature seed of 1-year-old aquatic herbal gorgon euryale seed in Nymphaeaceae, has the effects of tonifying kidney and securing essence, tonifying spleen and checking diarrhea, and clearing damp and stopping leukorrhagia, is a reputation of 'underwater ginseng' and 'underwater longan', and is a traditional Chinese medicinal material and a precious natural tonic. Fructus Alpinae Oxyphyllae is dry mature fruit of Zingiberaceae plant, and is collected in summer and autumn when the fruit changes from green to red. Fructus alpiniae oxyphyllae contains volatile oil, the main components of the volatile oil are sesquiterpenes such as eucalyptol, zingiberene and gingerol, the volatile oil contains rich vitamin B and vitamin C and trace elements such as manganese, zinc, potassium, sodium, calcium, magnesium, phosphorus, iron and copper, and the volatile oil has the main functions of warming spleen, checking diarrhea, warming kidney, controlling nocturnal emission and reducing urination. The spina date seed is a dry mature seed of a Rhamnaceae plant wild jujube, is sweet in taste and neutral in nature, enters heart and liver meridians, is a common traditional Chinese medicine, and has the clinical effects of nourishing the liver, calming the heart and soothing the nerves. Modern pharmacological research shows that the spina date seed contains various components such as flavonoid glycoside, triterpenes, saponins, organic acids and the like, so the spina date seed can effectively calm and calm the nerves, has obvious curative effect on insomnia patients, and can obviously improve the sleep condition mainly by regulating qi and blood functions of internal organs of a human body and rarely generate toxic or side effect. For insomnia with blood failing to enter spleen, Zi Su ren should be used to tonify heart and spleen, so blood entering spleen, five zang and an peace, sleeping peace. Researches show that the spina date seeds mainly affect the deep sleep stage of slow-wave sleep, so that the average time of deep sleep is prolonged, the attack frequency is increased, and the treatment purpose is easily achieved.
In the present invention, through Zhang Zhongjing, it is recorded in "jin Kui Yao L ü e": insomnia is caused by liver blood deficiency and yin deficiency with internal heat, and is indicated for tonifying blood and regulating liver, nourishing heart and tranquilizing mind, clearing heat and relieving restlessness, so as to relieve symptoms of liver blood deficiency, heart-mind tranquilization and restlessness due to deficiency. According to the traditional Chinese medicine analysis, liver storing soul, internal fire, liver blood deficiency and heart disturbing cause uneasiness, so that vexation, insomnia and palpitation occur; dizziness due to disturbance of the deficient yang, and vertigo; night sweating due to deficiency heat forcing the body fluids to discharge; a dry throat and mouth with a thready, wiry or rapid pulse is the condition of yin deficiency with internal heat. Therefore, the invention uses the stem and leaf of the panax notoginseng as monarch drug for tranquilization and nourishing the heart and improving the blood supply of the brain; the tuckahoe, the heart calming and the mind tranquilizing, and the cassia seed, the bitter cold and moist, are used as ministerial drugs; the spina date seed is used for greatly tonifying heart and spleen and regulating qi activity, is matched with monarch drug, is used together with pungent powder for assisting each other in sour recovery and nourishing blood, regulating liver and soothing nerves; the raw sharpleaf galangal fruit is used for regulating the middle warmer and relieving urgency, harmonizing the medicines, tonifying spleen and regulating the middle warmer by being matched with tuckahoe, and nourishing liver yin by being combined with spina date seed acid, and is used as a guiding medicine, so that the insomnia condition can be easily improved by the health-care tea, and the health-care tea is safe and has no toxic or side effect by being combined with yin and yang; the spina date seed can effectively calm and calm the nerves by various components such as flavonoid glycoside, triterpene, saponin, organic acid and the like contained in the spina date seed, has obvious curative effect on insomnia patients, obviously improves the sleep condition by mainly regulating qi and blood functions of internal organs of a human body, rarely generates toxic and side effects, mainly influences the deep sleep stage of slow wave sleep, prolongs the average time of deep sleep, increases the attack frequency and further easily achieves the treatment purpose; by providing multiple using methods, a user can easily select a proper mode, autonomous selectivity is improved, and the user having a psychological disorder to medicines can directly apply the medicine to the navel to ensure that the medicines are absorbed in all directions; the traditional Chinese medicine preparation for treating insomnia provided by the invention supplements each other, has simple components, is safe and has no toxic or side effect.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.
Claims (10)
1. The Chinese herbal medicine for adjuvant therapy of insomnia is characterized by comprising the following raw materials in parts by weight: 27-42 parts of pseudo-ginseng stem leaves, 13-27 parts of poria cocos, 8-22 parts of semen cassiae, 3-17 parts of semen euryales, 3-17 parts of fructus alpiniae oxyphyllae and 3-17 parts of spina date seeds.
2. The Chinese herbal medicine for adjuvant therapy of insomnia according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 35 parts of pseudo-ginseng stem leaves, 20 parts of poria cocos, 15 parts of semen cassiae, 10 parts of semen euryales, 10 parts of fructus alpiniae oxyphyllae and 10 parts of spina date seeds.
3. The Chinese herbal medicine for the adjuvant treatment of insomnia according to claim 1, wherein the preparation method comprises the following steps:
the method comprises the following steps: processing the cassia seeds in parts by weight at the temperature of 60-100 ℃, and stir-frying until the crackling sound of the cassia seeds in the whole pot begins to reduce on the principle of stir-frying.
Step two: pouring the stem leaves of the pseudo-ginseng into a certain container, smashing the stem leaves of the pseudo-ginseng into coarse powder for later use, adding 10 times of 41-65% ethanol (V/W), carrying out primary heating reflux extraction for 1-3 hours to obtain an extracting solution a, carrying out secondary heating reflux extraction for 1 hour to obtain an extracting solution b, combining the extracting solution a and the extracting solution b, and concentrating the obtained mixture to obtain the pseudo-ginseng crude extract with the amount of about 0.5 time of the raw materials.
Step three: weighing Poria, semen euryales, fructus Alpinae Oxyphyllae, and semen Ziziphi Spinosae at a given ratio, pouring the raw materials into a container, pouring the parched semen Cassiae into the container, adding 10 times of purified water, boiling with strong fire, decocting with slow fire for 0.5-5 hr, and filtering to obtain medicinal liquid c.
Step four: adding 6 times of purified water into the residue, boiling, decocting with slow fire for 0.5-5 hr, and filtering to obtain medicinal liquid d.
Step five: and mixing the liquid medicine c and the liquid medicine d, and filtering the mixture through a 50-mesh stainless steel screen to obtain liquid medicine e.
Step six: mixing the liquid medicine e and the pseudo-ginseng crude extract uniformly, concentrating in a concentration tank to a relative specific gravity of 1.10-1.30g/ml, and filtering with a stainless steel filter screen of 200 meshes to obtain a liquid medicine f.
Step seven: adding adjuvants into the liquid medicine f, mixing and stirring for 15 min to obtain a mixture g, and vacuum packaging under aseptic condition.
4. The Chinese herbal medicine for adjuvant therapy of insomnia as claimed in claim 1, wherein the temperature in the first step is 80 ℃.
5. The Chinese herbal medicine for adjuvant therapy of insomnia as claimed in claim 1, wherein the concentration of ethanol in the second step is 45%.
6. The Chinese herbal medicine for adjuvant therapy of insomnia as claimed in claim 1, wherein in said step two, the primary extraction is performed for 2 hours.
7. The Chinese herbal medicine for adjuvant therapy of insomnia as claimed in claim 1, wherein in step three and step four, the Chinese herbal medicine is cooked with slow fire for 2 hours.
8. The Chinese herbal medicine for adjuvant therapy of insomnia as claimed in claim 1, wherein the liquid medicine c in the sixth step is concentrated to a relative specific gravity of 1.180-1.200 g/ml.
9. The Chinese herbal medicine for adjuvant therapy of insomnia as claimed in claim 1, wherein the seven excipients in the step are one or more of gamma-aminobutyric acid, pectin, xylitol and essence.
10. The Chinese herbal medicine for adjuvant therapy of insomnia as claimed in claim 1, wherein the application method comprises the steps of mixing the mixture g obtained in step seven with water, and sticking the mixture g onto the navel.
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