CN111714543A - Herbal essential oil with sterilization effect and preparation method and application thereof - Google Patents

Herbal essential oil with sterilization effect and preparation method and application thereof Download PDF

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Publication number
CN111714543A
CN111714543A CN202010407925.3A CN202010407925A CN111714543A CN 111714543 A CN111714543 A CN 111714543A CN 202010407925 A CN202010407925 A CN 202010407925A CN 111714543 A CN111714543 A CN 111714543A
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Prior art keywords
oil
antibacterial
leaf
essential oil
essential
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邓小琳
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Guangzhou Crystal Garden Organic Health Industry Co ltd
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Guangzhou Crystal Garden Organic Health Industry Co ltd
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • A—HUMAN NECESSITIES
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    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
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Abstract

The invention relates to a herbal essential oil with a sterilization effect, which comprises the following components in percentage by mass: 11-15% of Ceylon cinnamon bark oil, 7-12% of rosemary extract, 6-13% of Pelargonium graveolens leaf oil, 7-14% of thyme extract, 6-13% of Melaleuca leucadendra leaf oil, 5-9% of Eucalyptus globulus leaf oil, 5-9% of Cedar pine bark oil, 5-9% of mastic oil, 2-7% of Melaleuca alternifolia leaf oil, 2-7% of clove bud oil, 2-7% of California oil, 1-5% of Selaginella moellendorffii oil, 1-5% of bergamot fruit extract, 1-5% of mint leaf oil and 1-5% of Juniperus procumbens fruit oil. The essential oil prepared by the invention has good bactericidal effect and no stimulation to skin; the essential oil can be used for preparing antibacterial spray, antibacterial balm, antibacterial hand sanitizer, antibacterial no-clean hand sanitizer or antibacterial handmade soap.

Description

Herbal essential oil with sterilization effect and preparation method and application thereof
Technical Field
The invention relates to herbal essential oil with a sterilization effect, and a preparation method and application thereof, and belongs to the technical field of aromatherapy essential oil.
Background
With the expansion of the range of activities of people and the diversity of life styles, people generate a large amount of domestic garbage every day, wherein the domestic garbage contains a large amount of bacteria and viruses, and some domestic garbage float in the air along with the flow of air, so that the health of people is threatened. For pathogenic microorganisms serving as transmission media, disinfectants are often used to kill or eliminate the pathogenic microorganisms to cut off the transmission of infectious diseases. Most of the sterilizing and disinfecting solutions used in the market are chemical synthetic preparations or fermentation preparations, and have strong killing effects on harmful organisms such as germs and insects. However, long-term use of these disinfectants can cause the enhancement of the tolerance of germs, so that the sterilization and disinfection effect is gradually weakened, and the sterilization and disinfection agents have great stimulation to the respiratory system, skin and mucous membrane of human body, and can cause certain damage to human body when being improperly used.
Plant essential oil is a secondary metabolite of plants, and is a general name of an oily liquid substance with high volatility and small molecular weight, which is extracted from parts such as flowers, green parts (leaves and stems), barks, twigs, fruits, fruit peels, seeds or roots by distillation, freeze pressing, extraction and the like.
The bacteriostatic activity or other biological activity of the plant essential oil is directly related to the existence form of volatile active ingredients of the plant essential oil. Many researches prove that most of plant essential oil with antibacterial activity is derived from spice in food and Chinese herbal medicine, wherein small molecular phenols, terpenes and aldehydes and ketones are main antibacterial active ingredients of the plant essential oil. It has been reported that plant essential oils possess antibacterial activity properties due to their ability to penetrate the cell membrane of bacteria and enter the interior of cells, exhibiting antibacterial activity in terms of functional properties of the cells and their lipophilic properties.
Therefore, the essential oil, especially the compound essential oil, has important significance in the aspect of sterilization.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provide the herbal essential oil with the sterilization effect and the preparation method and the application thereof.
In order to achieve the purpose, the invention adopts the technical scheme that: the herbal essential oil with the bactericidal effect comprises the following components in percentage by mass: 11-15% of Ceylon cinnamon bark oil, 7-12% of rosemary extract, 6-13% of Pelargonium graveolens leaf oil, 7-14% of thyme extract, 6-13% of Melaleuca leucadendra leaf oil, 5-9% of Eucalyptus globulus leaf oil, 5-9% of Cedar pine bark oil, 5-9% of mastic oil, 2-7% of Melaleuca alternifolia leaf oil, 2-7% of clove bud oil, 2-7% of California oil, 1-5% of Selaginella moellendorffii oil, 1-5% of bergamot fruit extract, 1-5% of mint leaf oil and 1-5% of Juniperus procumbens fruit oil.
According to the invention, Ceylon cinnamon bark oil, rosemary extract, geranium leaf oil, thyme extract, Melaleuca alternifolia leaf oil, Eucalyptus globulus leaf oil, Cedar pine bark oil, frankincense oil, alternate leaf Melaleuca alternifolia leaf oil, clove bud oil, oregano flower oil, Juniperus communis Wood oil, fingered citron fruit extract, mint leaf oil and Juniperus communis fruit oil are mixed according to a ratio, and the prepared essential oil has a good sterilization effect and has no stimulation to skin.
As a preferred embodiment of the essential oil, the essential oil comprises the following components in percentage by mass: 11% of cinnamomum zeylanicum bark oil, 8.6% of rosemary extract, 10.2% of geranium leaf oil, 9.8% of thyme extract, 8% of melaleuca viridis leaf oil, 9% of eucalyptus globulus leaf oil, 6.2% of cedar bark oil, 8.4% of frankincense oil, 5.8% of alternate leaf melaleuca viridis leaf oil, 7% of clove bud oil, 4% of oregano flower oil, 3.5% of juniper wood oil, 5% of bergamot fruit extract, 2% of mint leaf oil and 1.5% of juniper oil.
In a second aspect, the invention provides a preparation method of the essential oil, which comprises the following steps: the herbal essential oil with the sterilization effect is obtained by uniformly mixing all the components.
The application method of the herbal essential oil comprises the following steps:
(1) it can be carried about, inhaled by abdominal breathing, and used for purifying respiratory tract.
(2) The air purifier is used for air purification of living rooms, sleeping rooms, offices and washrooms by means of an aromatherapy furnace or an aromatherapy machine. In spring and winter, a candle aromatherapy furnace (damp in spring with shaoyang; cold in winter with taiyin) is used, and in summer and autumn, a water mist aromatherapy machine (dry in summer with dry heat in summer and dry in autumn with shaoyin in autumn) is used. The tea is smoked once a day and 4-8 drops every time for half an hour.
(3) And (4) once a week, dripping 1-2 drops to the edge of a wardrobe, and preventing insects and removing mites.
(4) After the changed underwear is cleaned, the underwear is dropped into 1 drop to be soaked in water for 5 minutes to kill fungi.
(5) 6-8 drops are dropped during bathing to promote metabolism and help the body to expel toxin (particularly, the bathing is particularly effective when cold starts, and the people pay attention to timely dry the bath).
(6) The DIY is used for preparing natural antibacterial essential oil spray, essential oil balm, essential oil hand sanitizer and essential oil water-free hand sanitizer, plastic waste is reduced, the environment is protected, and the health of family members is protected.
In a third aspect, the invention provides the use of the essential oil in an antibacterial agent.
As a preferred embodiment of the application of the present invention, the antibacterial agent is an antibacterial spray, an antibacterial balm, an antibacterial hand sanitizer, an antibacterial leave-on hand sanitizer or an antibacterial handmade soap.
In a fourth aspect, the present invention provides an antibacterial spray comprising the above essential oil.
In a fifth aspect, the invention provides an antibacterial balm, which comprises the essential oil.
In a sixth aspect, the invention provides an antibacterial hand sanitizer, which contains the essential oil.
In a seventh aspect, the invention provides an antibacterial no-clean hand sanitizer, which contains the above essential oil.
In an eighth aspect, the present invention provides an antibacterial handmade soap comprising the above essential oil.
Compared with the prior art, the invention has the beneficial effects that: according to the invention, Ceylon cinnamon bark oil, rosemary extract, geranium leaf oil, thyme extract, Melaleuca alternifolia leaf oil, Eucalyptus globulus leaf oil, Cedar pine bark oil, frankincense oil, alternate leaf Melaleuca alternifolia leaf oil, clove bud oil, oregano flower oil, Juniperus communis Wood oil, fingered citron fruit extract, mint leaf oil and Juniperus communis fruit oil are mixed according to a ratio, and the prepared essential oil has a good sterilization effect and has no stimulation to skin; the essential oil can be used for preparing antibacterial spray, antibacterial balm, antibacterial hand sanitizer, antibacterial no-clean hand sanitizer or antibacterial handmade soap.
Detailed Description
To better illustrate the objects, aspects and advantages of the present invention, the present invention will be further described with reference to specific examples.
Examples 1 to 6
Examples 1-6 the amounts of the components of the herbal essential oil are shown in Table 1.
TABLE 1
Figure BDA0002492082880000041
The preparation method of the herbal essential oil of the embodiment 1-6 comprises the following steps: the herbal essential oil with the sterilization effect is obtained by uniformly mixing all the components.
Comparative example 1
Compared with example 2, the herbal essential oil of the comparative example does not contain geranium leaf oil, thyme extract and melaleuca viridis leaf oil.
Comparative example 2
Compared with example 2, the herbal essential oil of the comparative example does not contain eucalyptus globulus oil.
Comparative example 3
Compared with example 2, the herbal essential oil of the comparative example does not contain the bark oil of Cedar pine and mastic oil.
Comparative example 4
Compared with the example 2, the herbal essential oil of the comparative example does not contain the melaleuca alternifolia leaf oil and the clove bud oil.
Comparative example 5
Compared with example 2, the herbal essential oil of the comparative example does not contain melaleuca alternifolia leaf oil and origanum vulgare flower oil.
Comparative example 6
Compared with the example 2, the herbal essential oil of the comparative example does not contain the arborvitae oil and the bergamot fruit extract.
Comparative example 7
Compared with the example 2, the herbal essential oil of the comparative example does not contain mint leaf oil and juniper berries oil.
Comparative example 8
Compared with example 2, the herbal essential oil of this comparative example does not contain thyme extract, melaleuca viridis leaf oil, melaleuca alternifolia leaf oil, and marjoram flower oil.
Examples of effects
(1) Medium Sterilization test
Experimental strains: staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, and Candida albicans were purchased from the institute of microbiology, national academy of sciences.
Experimental reagent: the experimental group is the herbal essential oil prepared in the examples 1-6 and the comparative examples 1-8.
The experimental method comprises the following steps:
determination of zone of inhibition and rate of sterilization
0.1ml of bacterial suspension (5.5X 10 concentration) was added to each dish7cfu/ml), spread over the entire medium surface, and adsorbed at 35 ℃ for 30 min. Then, 4 sterile stainless steel oxford cups with the diameter of 6mm are uniformly prevented on the culture medium, 200 mu L of experimental reagent with the concentration of 10mg/L is added into the holes by a pipette, after the constant temperature culture is carried out for 24h at the temperature of 35 ℃, the diameter of the inhibition zone is tested and recorded, each treatment is repeated for 3 times, and the average value is calculated. The results of the bactericidal zone of inhibition tests of examples 1 to 6 and comparative examples 1 to 8 are shown in tables 2 and 3, respectively, and the results of the bactericidal sterilization rate test are shown in tables 4 and 5, respectively.
Determination of minimum inhibitory concentration
Taking 13 test tubes, adding 1ml of broth culture medium respectively, then adding 1ml of prepared experimental reagent solution with 0.5-10mg/L and 12 series concentrations respectively, taking the 13 th test tube as a blank control group, adding 0.1ml of bacterial liquid with corrected concentration into each tube, mixing uniformly, and culturing at constant temperature of 35 ℃ for 24 h. The results of the minimum inhibitory concentration test for examples 1 to 6 and comparative examples 1 to 8 are shown in tables 6 and 7, respectively.
TABLE 2
Figure BDA0002492082880000061
TABLE 3
Figure BDA0002492082880000062
Figure BDA0002492082880000071
TABLE 4
Figure BDA0002492082880000072
TABLE 5
Figure BDA0002492082880000073
TABLE 6
Figure BDA0002492082880000074
Figure BDA0002492082880000081
TABLE 7
Figure BDA0002492082880000082
As shown in tables 2 to 7, the essential oils prepared in examples 1 to 6 have a wide bacteriostatic range, a high sterilization rate and a low minimum inhibitory concentration against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa and Candida albicans. The essential oil prepared in example 2 has the widest bacteriostatic circle, the highest sterilization rate and the lowest bacteriostatic concentration. Comparative examples 1 to 8 do not contain all the components of the invention, and the prepared essential oil has a sterilizing and bacteriostatic effect which is not as good as that of the invention.
(2) Air sterilization test
Respectively in an area of 11.3m2And (4) performing air sterilization test in a large room.
And (3) one-time sterilization comparison: the experimental group is that essential oil prepared in the embodiment 1-6 is used for fumigation and sterilization at 65 ℃ for 2 hours; sterilizing the control group with ultraviolet lamp irradiation for 2 hr with lamp power of 0.75/m2。
And (3) detecting the number of settled colonies before and after disinfection and sterilization respectively for each group, and evaluating the air sterilization effect according to the difference of the number of settled colonies before and after disinfection and sterilization.
And (3) continuous sterilization comparison: the experimental group used the essential oil prepared in examples 1-6 to fumigate and sterilize for 8h and 24h at 65 ℃, and then the number of settled colonies was measured again; after the control group is sterilized by ultraviolet irradiation for 8h and 24h, the number of settled colonies is measured again.
The results of the air sterilization test of the essential oils prepared in examples 1 to 6 are shown in table 8.
TABLE 8
Figure BDA0002492082880000091
Figure BDA0002492082880000101
As can be seen from Table 8, the herbal essential oil prepared by the invention still has good bactericidal effect in air, so that the herbal essential oil can be applied to bactericidal spray and can achieve good bactericidal effect. Among them, the herbal essential oil prepared in example 2 has the best bactericidal effect in the air.
(3) Skin irritation test
48 mice with half of each male and female are randomly divided into 8 groups, 6 mice (3 mice each male and female) in each group respectively correspond to the herbal essential oil and the jojoba oil in the test examples 1-6, and the other group is used as a blank control.
Shearing hair on the back and both sides of white rat, unhairing with 8% sodium sulfide for 3 x 4cm2Keeping the skin intact. Each group was evenly smeared with 2 ml/piece of the corresponding experimental sample and fixed with sterile gauze and transparent adhesive tape, and a blank control group was smeared with 1 ml/piece of physiological saline and then fed in a single cage. And removing the test object after the sample is smeared for 24h, and visually observing whether the tested part of the depilation region has erythema and edema after 1h, 24h, 48h and 72h, and carrying out statistical analysis. The test results are shown in table 9.
The evaluation criteria of the skin irritation scoring standard meter are as follows:
the stimulation score is the total score of erythema response + edema response/number of animals, stimulation score < 0.5 is no stimulation, stimulation score < 3 is mild stimulation, stimulation score < 6 is moderate stimulation, and stimulation score > 6 is intensity stimulation.
TABLE 9
Figure BDA0002492082880000102
Figure BDA0002492082880000111
As can be seen from Table 9, the herbal essential oil prepared by the present invention is non-irritating to the skin and non-irritating after long-term use.
Example 7 antimicrobial spray
Raw materials: 100ml of tea plant hydrolat 1, 15ml of spray bottles 2, and the essential oil prepared in example 2.
The preparation method comprises the following steps: pouring the tea tree hydrolat into a 15ml spray bottle, dripping 8 drops of the essential oil prepared in the example 2, and uniformly shaking.
Use of antibacterial sprays:
(1) the space sprays, conveniently carries.
(2) Can be safely sprayed on the skin to expel parasites and sterilize.
(3) After the hair is washed and dried to 7 months, the scalp is sprayed, and the problems of scalp inflammation and dandruff are solved.
(4) It can be used for spraying shoes and shoe cabinet to inhibit bacteria.
Example 8 antibacterial balm
Raw materials: 50g of shea butter, 2 small aluminum boxes with the volume of 5ml, 1 glass rod, 1 small wooden spoon and the essential oil prepared in the example 2.
The preparation method comprises the following steps: heating over water to melt shea butter, spooning into a small aluminum box, dripping 3 drops of the essential oil prepared in example 2, stirring slightly, placing in a refrigerator, and solidifying after half an hour to obtain the product.
The application of the antibacterial balm comprises the following steps:
(1) it can be applied to neck and throat to relieve cough and stop phlegm.
(2) Solving the problem of skin fungal infection: itching and peeling of soles and toes, and direct application to affected parts; itching and inflammation at private parts can be applied to the inner side of thigh root, so as to avoid directly applying on affected parts; the armpit has peculiar smell, and can be directly smeared after bathing.
(3) Skin inflammation diminishing and toxin expelling: pox, pustule, can be directly applied; can be directly applied to affected part for treating scald and hemorrhage.
(4) Health protection and immunity enhancement: getting up in the morning every day, smearing one sole center, rubbing and massaging the two soles for 50 times, and then feeling that heat rises from the soles and the quantity is sufficient all day long; can be applied to ZHONG acupoint, JIA acupoint, and YINTANG acupoint to restore spirit when people have fatigue during noon rest or work and driving.
EXAMPLE 9 antibacterial hand sanitizer
Raw materials: 3 bags of cold-made olive oil handmade soap strips (the mature period is 1 month, the soap strips can be used immediately), 1 each of 100ml beakers and 5ml beakers, 1 glass stirring rod, 1 mousse bottle of 250ml, 1 mousse bottle of 50ml portable, 3 ceramic aromatherapy furnace sets of large capacity, 5 smokeless candles and the essential oil prepared in example 2.
The preparation method comprises the following steps: putting the soap shreds into a big beaker, pouring 20ml of purified water, igniting the candle, and slowly melting the soap shreds; pouring the melted concentrated soap liquid into a mousse bottle, and continuously filling purified water; pouring the essential oil (in a proportion of 3%) prepared in example 2 into a mousse bottle in a small beaker amount of 8 ml; the cover is tightly twisted and uniformly shaken.
The application of the antibacterial hand sanitizer comprises the following steps: safe sterilization and disinfection, and skin protection.
Example 10 antibacterial leave-on hand sanitizer
Raw materials: 1 box of 300g of aloe vera gel, 1 piece of 100ml of 75% alcohol, 30ml of sweet almond oil, 1 piece of 100ml beaker, 1 piece of glass stirring rod, 2 pieces of 60ml squeeze bottle, 1 piece of small wooden spoon and the essential oil prepared in example 2.
The preparation method comprises the following steps: 3 spoons of aloe gel are put into a beaker, and alcohol is poured into the beaker until the volume of the alcohol reaches 50ml of the scale mark; 5ml of almond oil is poured in; dripping 36 drops of the essential oil obtained in example 2 (in a proportion of 3%); stirring, and bottling.
The usage of the antibacterial and water-free hand sanitizer is as follows: convenient to use at any time, safe to sterilize and protect the skin.
Example 11 antibacterial handmade soap
Raw materials: 2 bags of cold-made olive oil handmade soap chips (which can be used immediately after the mature period of 1 month), 50g of shea butter, 1 100ml of beakers, 1 glass stirring rod, 1 small wooden spoon, 1 handmade soap mold, portable foaming mesh bags, the essential oil prepared in example 2, 3 ceramic aromatherapy furnaces and 5 smokeless candles.
The preparation method comprises the following steps: igniting the aromatherapy furnace, pouring a bag of 50g of soap shreds into a beaker, and slowly melting; adding a spoon of shea butter; finally, 8 drops of the essential oil prepared in the example 2 are added; uniformly stirring, pouring into a mould, and then putting into a refrigerator for cooling; and (5) after shaping, demolding and using.
The antibacterial essential oil handmade soap comprises the following components in part by weight: inhibiting bacteria, nourishing skin, washing face and bathing, and can be used by rubbing and foaming in foaming net, and is convenient for carrying and suitable for adults and children.
Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting the protection scope of the present invention, and although the present invention is described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions can be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.

Claims (10)

1. The herbal essential oil with the bactericidal effect is characterized by comprising the following components in percentage by mass: 11-15% of Ceylon cinnamon bark oil, 7-12% of rosemary extract, 6-13% of Pelargonium graveolens leaf oil, 7-14% of thyme extract, 6-13% of Melaleuca leucadendra leaf oil, 5-9% of Eucalyptus globulus leaf oil, 5-9% of Cedar pine bark oil, 5-9% of mastic oil, 2-7% of Melaleuca alternifolia leaf oil, 2-7% of clove bud oil, 2-7% of California oil, 1-5% of Selaginella moellendorffii oil, 1-5% of bergamot fruit extract, 1-5% of mint leaf oil and 1-5% of Juniperus procumbens fruit oil.
2. The essential oil according to claim 1, comprising the following components in percentage by mass: 11% of cinnamomum zeylanicum bark oil, 8.6% of rosemary extract, 10.2% of geranium leaf oil, 9.8% of thyme extract, 8% of melaleuca viridis leaf oil, 9% of eucalyptus globulus leaf oil, 6.2% of cedar bark oil, 8.4% of frankincense oil, 5.8% of alternate leaf melaleuca viridis leaf oil, 7% of clove bud oil, 4% of oregano flower oil, 3.5% of juniper wood oil, 5% of bergamot fruit extract, 2% of mint leaf oil and 1.5% of juniper oil.
3. A process for the preparation of an essential oil according to any one of claims 1 to 2, comprising the steps of: the herbal essential oil with the sterilization effect is obtained by uniformly mixing all the components.
4. Use of an essential oil according to any one of claims 1 to 2 in an antimicrobial agent.
5. The use of claim 4, wherein the antibacterial agent is an antibacterial spray, an antibacterial balm, an antibacterial hand sanitizer, an antibacterial leave-on hand sanitizer, or an antibacterial hand soap.
6. An antimicrobial spray comprising an essential oil according to any one of claims 1 to 2.
7. An antibacterial balm, characterized in that the antibacterial balm comprises the essential oil according to any one of claims 1 to 2.
8. An antibacterial hand sanitizer, which is characterized by comprising the essential oil as claimed in any one of claims 1 to 2.
9. An antibacterial no-clean hand sanitizer, characterized in that the antibacterial no-clean hand sanitizer comprises the essential oil of any one of claims 1 to 2.
10. An antibacterial handmade soap comprising the essential oil according to any one of claims 1 to 2.
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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112514926A (en) * 2020-12-14 2021-03-19 杭州象外环保科技有限公司 Natural plant extract essential oil disinfectant for inactivating coronavirus and application thereof
CN112913858A (en) * 2021-04-23 2021-06-08 云南自然谷生物开发有限公司 Plant disinfectant for public places
CN113304186A (en) * 2021-05-26 2021-08-27 上海橙果生物工程有限公司 Skin cream capable of relieving joint pain and improving joint vitality as well as preparation method and using method thereof
CN114522121A (en) * 2021-12-30 2022-05-24 彭氏(惠州)实业发展有限公司 Oil control spray containing plant essential oil and preparation method thereof
CN115500361A (en) * 2022-09-27 2022-12-23 上海家化联合股份有限公司 Water-based product containing peppermint leaf oil and mite killing application thereof
CN115708794A (en) * 2023-01-09 2023-02-24 同芙集团(中国)股份有限公司 Antibacterial essential oil

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105307633A (en) * 2013-03-18 2016-02-03 瑟拉诺维斯两合有限公司 Composition for oral care

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105307633A (en) * 2013-03-18 2016-02-03 瑟拉诺维斯两合有限公司 Composition for oral care

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ANNAW12502: "精油是如何对抗细菌的？99%的人都不知道", 《HTTP://WWW.360DOC.COM/CONTENT/20/0218/18/30276536_892977065.SHTML》 *
海哭蓝天: "《精油手册》动脉瘤、抗菌剂、MRSA、葡萄球菌、抗真菌剂、运动员脚病、念珠菌、霉菌、环癣、鹅口疮", 《HTTPS://WWW.PINLUE.COM/ARTICLE/2019/11/1917/249809173822.HTML》 *
火鹤花: "祛痘洁肤棒 - 爱问共享资料", 《HTTP://ISHARE.IASK.SINA.COM.CN/F/16257802.HTML》 *

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112514926A (en) * 2020-12-14 2021-03-19 杭州象外环保科技有限公司 Natural plant extract essential oil disinfectant for inactivating coronavirus and application thereof
CN112514926B (en) * 2020-12-14 2021-10-01 杭州象外环保科技有限公司 Natural plant extract essential oil disinfectant for inactivating coronavirus and application thereof
CN112913858A (en) * 2021-04-23 2021-06-08 云南自然谷生物开发有限公司 Plant disinfectant for public places
CN113304186A (en) * 2021-05-26 2021-08-27 上海橙果生物工程有限公司 Skin cream capable of relieving joint pain and improving joint vitality as well as preparation method and using method thereof
CN114522121A (en) * 2021-12-30 2022-05-24 彭氏(惠州)实业发展有限公司 Oil control spray containing plant essential oil and preparation method thereof
CN115500361A (en) * 2022-09-27 2022-12-23 上海家化联合股份有限公司 Water-based product containing peppermint leaf oil and mite killing application thereof
CN115708794A (en) * 2023-01-09 2023-02-24 同芙集团(中国)股份有限公司 Antibacterial essential oil

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