CN111714542B

CN111714542B - Formula and application of moxibustion strip or moxibustion column for treating allergic rhinitis

Info

Publication number: CN111714542B
Application number: CN202010750538.XA
Authority: CN
Inventors: 李蔚江; 姚斐; 赵琛
Original assignee: Shanghai University of Traditional Chinese Medicine
Current assignee: Shanghai University of Traditional Chinese Medicine
Priority date: 2020-07-30
Filing date: 2020-07-30
Publication date: 2022-06-10
Anticipated expiration: 2040-07-30
Also published as: CN111714542A

Abstract

The invention discloses a formula of a moxibustion stick or moxibustion column for treating allergic rhinitis and application thereof, wherein the formula comprises the following components in parts by weight: 70-80 parts of folium artemisiae argyi, 5-8 parts of snakegourd fruit, 5-8 parts of cocklebur fruit, 3-5 parts of divaricate saposhnikovia root, 3-5 parts of angelica dahurica, 1-3 parts of mint and 1-3 parts of asarum. The invention creatively provides a method for moxibustion with a prescription medicine for treating allergic rhinitis, and the prescription of the prescription medicine moxibustion stick or the prescription medicine moxibustion column for treating allergic rhinitis has the advantages of quick response to allergic rhinitis, small side effect, low cost, comfortable moxibustion process and great application prospect.

Description

Formula and application of moxibustion strip or moxibustion column for treating allergic rhinitis

Technical Field

The invention belongs to the technical field of traditional Chinese medicine moxibustion, and relates to a formula of a moxibustion strip or a moxibustion column for treating allergic rhinitis and application thereof.

Background

Allergic rhinitis is allergic rhinitis, which is a multifactorial disease induced by the interaction of genes with the environment. Risk factors for allergic rhinitis may be present in all age groups. The typical symptoms of allergic rhinitis are mainly paroxysmal sneezing, watery nasal discharge, nasal obstruction and nasal itching, and are partially accompanied by hyposmia.

The current treatment scheme for the disease mainly comprises the following steps: (1) the medicine therapy mainly comprises antihistamine (2 administration methods including oral administration and nasal spray, mainly H1 antihistamine), glucocorticoid (budesonide, mometasone furoate and the like), decongestant, anticholinergic medicine (0.03% ipratropium bromide is sprayed to the nose), mast cell stabilizer (generally 4% sodium cromoglycate solvent is used for dripping the nose) and anti-IgE antibody (Omazuril single antibody) therapy, wherein, patients with hypertension and cardiovascular diseases of the decongestant need to be cautiously treated by the decongestant, the induced rhinitis can be generated by the medicine after long-term use, nasal obstruction is aggravated, the treatment period of the anti-IgE antibody is long, the price is high, and the medicine therapy has the following defects: the nasal administration or the nasal cleaning can cause certain stimulation to mucous membrane of the nose, uncomfortable physical feeling can be caused, and the patient is difficult to insist on treatment; (2) surgical treatment, which, although it can improve the state of ventilation, currently has no current standard; (3) the traditional Chinese medicine treatment mainly comprises traditional Chinese medicines and acupuncture treatment.

Moxibustion therapy is one of the traditional external treatment methods in traditional Chinese medicine. The special medicinal gas (volatile component in medicine) generated by igniting moxibustion material in moxibustion process combines infrared ray heat radiation effect to act on specific parts of body surface (channels and collaterals and acupoints), and the functional state of human body is adjusted by dual effects of medicine and channels and collaterals and acupoints, thereby achieving the purpose of preventing and treating diseases. Moxibustion therapy has been in China for two thousand years, and the treatment effect is proved by countless clinical practices. The moxibustion is a non-contact physical therapy of skin, has better safety, can be suitable for people of all ages, is more and more concerned and loved by people as a health therapy with small side effect, but moxibustion appliances and moxibustion methods for treating allergic rhinitis do not appear at present.

Therefore, the development of a formula of a moxibustion stick or moxibustion column for treating allergic rhinitis and a use method thereof have practical significance.

Disclosure of Invention

The invention aims to overcome the defects of drug side effect, uncomfortable treatment feeling, incapability of generating long-term continuous curative effect and the like in the process of treating allergic rhinitis in the prior art.

The moxibustion recommended by the scheme is a non-contact skin treatment method, has better safety and can be suitable for people of all ages. The warm and comfortable feeling in the moxibustion application process is more and more concerned and loved by the masses. And avoids the side effects of the inherent chemical drugs on human organs due to the physical therapy property.

The search shows that the moxibustion therapy formula and the appliance thereof specially used for treating allergic rhinitis do not exist at present. The invention provides a healthy and environment-friendly formula of a moxibustion stick or moxibustion column for treating allergic rhinitis with small side effect.

In order to achieve the above objects, the present invention provides a formula of a moxibustion stick or a moxibustion column, which is used by those skilled in the art to manufacture a moxibustion stick or a moxibustion column for treating allergic rhinitis.

The technical scheme of the invention is as follows:

a formula of a moxibustion stick or moxibustion column for treating allergic rhinitis comprises the following components in parts by weight:

folium artemisiae argyi: 70-80 parts of,

And (3) snakegourd fruit: 5-8 parts of,

Fructus xanthil: 5-8 parts of,

Wind prevention: 3-5 parts of,

Radix angelicae: 3-5 parts of,

Mint: 1-3 parts of,

Asarum: 1-3 parts.

The formulation of the formula is based on the theory of traditional Chinese medicine, and the composition of the formula reflects the principle of monarch, minister, assistant and guide of the traditional Chinese medicine prescription.

Traditional Chinese medicine is a medical science created by people working in China in long-term medical practice and is deeply influenced by the traditional culture thought of China. The combination of whole syndrome differentiation, treatment of both principal and secondary aspects of disease, prevention and treatment is the core thought and characteristic of traditional Chinese medicine. Although nasal obstruction, watery nasal discharge, sneezing and the like which are shown by allergic rhinitis belong to local symptoms of the nose, according to the theory of traditional Chinese medicine, the nose belongs to the lung system, and lung qi deficiency is an important pathogenesis of the disease. Allergic rhinitis is easy to relapse and is closely related to low immunity (lung qi weakness) of patients for a long time to recover. According to the theory of traditional Chinese medicine, the treatment of the disease not only focuses on the symptomatic treatment of clinical symptoms, but also needs to fundamentally improve the immunity of patients to achieve the effect of 'treating the disease without the illness'.

The formulation embodies the above ideas and considerations.

Folium artemisiae argyi is the most common material for moxibustion therapy in clinic at present. Folium Artemisiae Argyi has effects of warming channels for dispelling cold, activating qi-flowing, dredging collaterals, invigorating qi and blood, strengthening vital qi and eliminating pathogenic factor. The pathogenic wind-cold is the most common and main cause of allergic rhinitis, the warm effect generated by burning folium artemisiae argyi can effectively dispel cold (pathogenic qi) and expel cold, and the conduction effect along the channels in the moxibustion process can effectively open orifices and dredge the nose to treat nasal obstruction. Meanwhile, according to the meridian theory of the traditional Chinese medicine, the specific acupuncture points of the moxibustion can tonify lung qi, so that the immunity is improved, and the purposes of treating diseases and seeking the basis are achieved. Therefore, the argy wormwood leaves account for the largest proportion in the formula.

The snakegourd fruit has the effects of clearing heat and reducing phlegm, and can effectively aim at local inflammatory reaction and symptoms of running nose. Snakegourd fruit is used in combination with mugwort leaf, which is warm in nature and can be used for treating thin and clear nasal discharge (cold syndrome), while Snakegourd fruit is warm in nature and can be used for treating thick and yellow nasal discharge (heat syndrome). The two medicines are matched, so that the effect is more comprehensive.

Xanthium sibiricum is good at clearing nasal orifices, and is an essential drug for treating rhinitis. Nasal obstruction is a major symptom of allergic rhinitis. The resuscitation and nose opening are also important indexes for evaluating the curative effect of allergic rhinitis. The cocklebur fruit, the folium artemisiae argyi, the radix angelicae and the mint have the function of resuscitation, and the combination of a plurality of medicines can greatly improve the treatment effect speed, so that the scheme is a characteristic superior to other methods.

Fang Feng is warm in nature and pungent in flavor, and Xin san can relieve exterior syndrome and dispel wind. If the name is the same, ledebouriella root can resist wind evil. In addition, the argy wormwood leaves in the formula have the function of tonifying healthy energy, and the two medicines are matched to play the effects of strengthening healthy energy and eliminating evil, thereby reflecting the thoughts of treating diseases and treating the root causes and preventing and treating diseases in the traditional Chinese medicine.

Dahurian angelica root, radix Angelicae Dahuricae is pungent in flavor and warm in nature. It enters lung and stomach meridians. Has the effects of expelling wind and cold, and relieving pain. Headache of forehead is the most common accompanying symptom in allergic rhinitis, and radix angelicae is a special medicine for treating yangming headache (forehead headache), and can strengthen the function of cocklebur fruit for relieving nasal obstruction because of the function of relieving stuffy nose.

The mint has fragrant smell and light and transparent quality, can promote the opening of pores, increase the permeability of skin, lead the medicines into the lung and enter the nose, and enable the medicine effect to have more targeting property.

Asarum herb is good at treating nasosinusitis (running and running nose), and it is also a channel-inducing drug for lung meridian, and it is matched with peppermint, so that it can induce all the drugs into lung and enter nose, and quickly take effect.

In summary, the following steps: each medicine in the formula plays its own role; the temperature and the coolness are matched, and the yin and the yang are balanced; both prevention and treatment are considered, and both the principal and secondary aspects are treated.

The specific medicinal composition and proportion in the formula of the invention enable the treatment targeting (lung system) of the allergic rhinitis to be more accurate, the effect to be more rapid, the treatment to the root cause can be realized, the treatment effect can be longer due to the thoughts of preventing and treating the allergic rhinitis, and the above characteristics enable the allergic rhinitis to become the preferred formula.

In addition, the protection scope of the present invention is not limited thereto, and those skilled in the art can reasonably adjust the ratio or add other components within a certain range to optimize the treatment effect or treat other diseases simultaneously according to the actual conditions and syndrome differentiation results of patients in practical application.

The invention also provides a moxibustion stick prepared by the formula, wherein the moxibustion stick is cylindrical, the diameter of the moxibustion stick is 18mm, the length of the moxibustion stick is 200mm, and the mass of the moxibustion stick is 20 g/stick. The scope of the present invention is not limited thereto, and those skilled in the art can select the shape, size and weight of the moxibustion stick according to the actual situation, and only a feasible technical solution is provided here.

In addition, the invention also provides a moxibustion column prepared by the formula, wherein the moxibustion column is in a conical column shape, the diameter of the moxibustion column is 15mm, the length of the moxibustion column is 40mm, and the mass of the moxibustion column is 2 g per column. The scope of the present invention is not limited thereto, and the shape, size and weight of the moxibustion column can be selected by those skilled in the art according to the actual situation, and only one possible technical solution is provided herein.

Has the beneficial effects that:

the invention creatively provides moxibustion for treating allergic rhinitis, and the formula of the moxibustion stick or moxibustion column for treating allergic rhinitis has good and lasting curative effect on allergic rhinitis, small side effect and low cost, can relieve the economic pressure of patients on one hand, is beneficial to further application on the other hand, and has great application prospect.

Detailed Description

The following further illustrates embodiments of the invention.

Example 1

The formula of the moxibustion stick for treating allergic rhinitis comprises the following components in parts by weight:

folium artemisiae argyi: 70 portions of,

And (3) snakegourd fruit: 8 portions of,

Fructus xanthil: 8 portions of,

Wind prevention: 3 portions of,

Radix angelicae: 3 portions of,

Mint: 2 portions of,

Asarum: and 2 parts.

Moxa sticks are prepared according to the formula of example 1, the mugwort leaves are dried and crushed into moxa wool, the other medicines are mixed and crushed into powder (the fineness is 100 meshes), and then the powder is mixed with the moxa wool, and the moxa sticks are wrapped by mulberry paper to form the moxa sticks, the mass of each moxa stick is 20 g/piece, the moxa sticks are cylindrical, the diameter of each moxa stick is 18mm, and the length of each moxa stick is 200 mm. When the moxibustion strip is used, an operator holds the middle section of the moxibustion strip, and performs suspended moxibustion on Tianfu acupuncture points and Fengchi acupuncture points (two-side acupuncture points) at a proper distance away from the skin, wherein each point is 15-20 minutes, and 10 times of treatment is 1 course of treatment.

Moxibustion was performed on two patients with the following moxibustion stick:

patient 1 (example 1 formulation)

Wangwei, male, 38 years old;

symptoms are: allergic rhinitis has a history of more than 10 years, and sneezes tens of times every morning with itchy eyes. Pale tongue with teeth marks and white coating;

as a result: after 6 times of moxibustion, the symptoms disappeared. The VAS score before treatment is 7.0, 2.1 after treatment, and the difference between before and after VAS treatment is 4.9>1, thereby having obvious effect.

Patient 2: (formulation of example 1)

Wangli, maid, 43 years old;

symptoms are: the history of allergic rhinitis is more than 20 years, the main symptoms are nasal obstruction and sneezing, the tongue is pale, swollen and has tooth marks, and the tongue coating is thin;

as a result: after moxibustion for 5 times, the symptoms disappear, and then consolidation treatment is carried out for 5 times, and the patients are cured; the VAS score before treatment is 6.5, the VAS score after treatment is 0.5, and the difference between before and after VAS treatment is 6.0 to more than 1, so the effect is obvious.

Example 2

folium artemisiae argyi: 70 portions of,

And (3) snakegourd fruit: 5 portions of,

Fructus xanthil: 8 portions of,

Wind prevention: 3 portions of,

Radix angelicae: 5 portions of,

Mint: 2 portions of,

Asarum: and 2 parts of the raw materials.

The moxibustion stick was made in the same manner as in example 1, except for the formulation of the moxibustion stick.

Moxibustion was performed on two patients with the following moxibustion stick:

patient 3 (example 2 formulation):

zhangzhiling, female, 56 years old;

the patient with nasal obstruction and nasal discharge has a half year history, and is susceptible to fatigue, pale red tongue with thin coating and thready pulse.

As a result: the VAS score before treatment is 5.9, the VAS score after treatment is 1.4, and the difference between before and after VAS treatment is 4.5>1, so the effect is obvious.

Patient 4 (example 2 formulation):

wangzaicheng, male, age 42;

nasal obstruction, itching nose for 2 years, easy fatigue, pale and swollen tongue with teeth marks and slow pulse.

As a result: the VAS score before treatment is 4.8, the VAS score after treatment is 1.6, and the difference between before and after VAS treatment is 3.2 to more than 1, so the effect is obvious.

Example 3

The formula of the moxibustion column for treating allergic rhinitis comprises the following components in parts by weight:

folium artemisiae argyi: 80 portions of,

And (3) snakegourd fruit: 5 portions of,

Fructus xanthil: 8 portions of,

Wind prevention: 5 portions of,

Radix angelicae: 3 portions of,

Mint: 2 portions of,

Asarum: and 2 parts.

A moxibustion column was prepared according to the formulation of example 3, the moxa leaves were dried and crushed into moxa wool, the remaining drugs were mixed and crushed into powder (fineness 100 mesh), and then mixed with moxa wool, and wrapped with mulberry paper to form a moxibustion column, having a mass of 2 g/piece, a conical column shape, a diameter of 15mm, and a length of 40 mm. The application method of moxibustion column comprises sticking a specific support on Tianfu acupoint and Yunmen acupoint (acupoint on both sides), and performing moxibustion 3 columns each time, 10 times as a treatment course.

Moxibustion is performed on the following two patients by using moxibustion columns:

patient 5 (example 3 formulation):

peridium, woman, age 37;

the patient has more than 10 years of history of nasal discharge and sneezing, pale red tongue, tooth marks, tongue, stomach cold, and cold hands and feet;

as a result: the VAS score before treatment is 6.1, the VAS score after treatment is 2.3, and the difference between before and after VAS treatment is 3.8>1, so the effect is obvious.

Patient 6 (example 3 formulation):

some of the LVL, male, age 42;

nasal discharge and sneezing history for more than 15 years;

swollen tongue with teeth mark, thick coating in tongue, slippery pulse, normal stool and sleeping late.

As a result: before treatment, the VAS score is 2.1, after treatment, the VAS score is 0.6, and the difference between before and after VAS treatment is 1.5 to more than 1, so the effect is obvious.

Comparative example 1

The formula of the moxibustion stick comprises the following components in parts by weight:

folium artemisiae argyi: 80 portions of,

Fructus xanthil: 8 portions of,

Wind prevention: 3 portions of,

Radix angelicae: 3 portions of,

Mint: 2 portions of,

Asarum: and 2 parts.

Moxibustion was performed on two patients with the following moxibustion stick:

patient 7 (comparative example 1 formulation):

fix populus, male, 42 years old;

the patient has a history of nasal obstruction, sneezing and nasal discharge for 10 years

A deep sleep with a red tongue, a thick and greasy coating and a slippery and rapid pulse.

As a result: before treatment VAS score 6.1, after treatment VAS score 5.5, difference between before and after VAS 0.6<1, no effect.

Patient 8 (comparative example 1 formulation):

cynanchum paniculatum, female, 37 years old;

nasal obstruction and running nose for many years

A sore throat, fatigue, a pale red tongue with white coating and a deep and thready pulse

As a result: pre-treatment VAS score 6.7, post-treatment VAS score 6.5, with a difference of 0.2<1 before and after VAS, no effect.

Comparative example 2

folium artemisiae argyi: 80 portions of,

And (3) snakegourd fruit: 5 portions of,

Wind prevention: 3 portions of,

Radix angelicae: 3 portions of,

Mint: 2 portions of,

Asarum: and 2 parts.

Moxibustion was performed on two patients with the following moxibustion stick:

patient 9 (comparative example 2 formulation)

Julongqu, male, 40 years old

Nasal obstruction and sneezing history for 3 years

A dark red tongue with cracks, a thin coating and a wiry and thready pulse

As a result: pre-treatment VAS score 2.4, post-treatment VAS score 1.6, difference 0.8<1 before and after VAS, no effect.

Patient 10 (comparative example 2 formulation)

A permanent woman in 34 years old

Sneezing and nasal obstruction history for 10 years

A red tongue tip, a thin and yellow coating, discomfort in throat and a late sleep. The pulse is thready and rapid.

As a result: pre-treatment VAS score 2.1, post-treatment VAS score 1.5, difference 0.6<1 before and after VAS, no effect.

Comparative example 3

The formula of the moxibustion column comprises the following components in parts by weight:

folium artemisiae argyi: 80 portions of,

And (3) snakegourd fruit: 5 portions of,

Fructus xanthil: 8 portions of,

Radix angelicae: 3 portions of,

Mint: 2 portions of,

Asarum: and 2 parts.

The moxibustion column was fabricated in the same manner as in example 3, except for the formulation of the moxibustion column.

patient 11 (comparative example 3 formulation)

Yellow-red, female, age 44

Sneezing and nasal obstruction 20 years old

A pale-red tongue with thin coating and a thready pulse, which is apt to cause fatigue.

As a result: pre-treatment VAS score 4.2, post-treatment VAS score 3.6, difference 0.6<1 before and after VAS, no effect.

Patient 12 (comparative example 3 formulation)

Dubiao Rong, male, age 33

The patient has a history of nasal obstruction and nasal discharge for 10 years

Dark red tongue, cracks in tongue, yellow and greasy coating, and slippery pulse.

As a result: pre-treatment VAS score 4.4, post-treatment VAS score 4.9, difference-0.5 <1 before and after VAS, no effect.

Comparative example 4

folium artemisiae argyi: 80 portions of,

And (3) snakegourd fruit: 5 portions of,

Fructus xanthil: 8 portions of,

Wind prevention: 3 portions of,

Mint: 2 portions of,

Asarum: and 2 parts.

Moxibustion was performed on two patients with the following moxibustion stick:

patient 13 (comparative example 4 formulation)

Li Gong Hua, female, age 55

Nasal obstruction and running nose with history of 3 years

A pale red tongue with thin and white coating is easy to feel fatigue, poor sleep quality and a wiry pulse.

As a result: pre-treatment VAS score 7.1, post-treatment VAS score 7.0, difference 0.1<1 before and after VAS, no effect.

Patient 14 (comparative example 4 formulation)

Yao Yingbao for male, 45 years old

Nasal obstruction and sneezing history for 3 years

A red tongue with yellow coating, a slippery pulse and a late sleep.

As a result: pre-treatment VAS score 4.4, post-treatment VAS score 4.5, difference-0.1 <1 before and after VAS, no effect.

Comparative example 5

folium artemisiae argyi: 80 portions of,

And (3) snakegourd fruit: 5 portions of,

Fructus xanthil: 8 portions of,

Wind prevention: 3 portions of,

Radix angelicae: 3 portions of,

Asarum: and 2 parts.

patient 15 (comparative example 5 formulation)

Wu-Chi, male, age 48

The history of nasal obstruction and sneezing is 30 years

Pale and swollen with thin coating. The pulse is deep and wiry. It is easy to feel fatigue and cold hands and feet.

As a result: pre-treatment VAS score 5.0, post-treatment VAS score 5.0, difference 0<1 before and after VAS, no effect.

Patient 16 (comparative example 5 formulation)

Wangzhi, female, age 42

Sneezing and nasal discharge for 5 years

Sleep late, dry eyes, fatigue, pale tongue with thin coating, and thready pulse.

As a result: pre-treatment VAS score 2.0, post-treatment VAS score 1.9, difference 0.1<1 before and after VAS, no effect.

Comparative example 6

folium artemisiae argyi: 80 portions of,

And (3) snakegourd fruit: 5 portions of,

Fructus xanthil: 8 portions of,

Wind prevention: 3 portions of,

Radix angelicae: 3 portions of,

Mint: and 2 parts.

Moxibustion was performed on two patients with the following moxibustion stick:

patient 17 (comparative example 6 formulation)

Xue certain, male, age 49

Sneezing and nasal obstruction history for 5 years

A pale-red tongue with teeth marks, a thin coating and a deep and thready pulse.

As a result: pre-treatment VAS score 6.2, post-treatment VAS score 6.2, difference 0<1 before and after VAS, no effect.

Patient 18 (comparative example 6 formulation)

Wenying Ying, female, 52 years old

Nasal obstruction, sneezing and nasal discharge for 4 years

Fatigue, pale-red tongue with thin coating, cold hands and feet.

As a result: before treatment the VAS score was 5.3, after treatment the VAS score was 4.5, the difference between before and after VAS was 0.8<1, and was not effective.

By comparing the effects of the above examples, only the folium artemisiae argyi, the fructus trichosanthis, the fructus xanthil, the radix sileris, the radix angelicae, the mint and the asarum in the formula of the invention in a specific proportion can ensure that the folium artemisiae argyi, the fructus trichosanthis, the fructus xanthil, the radix sileris, the radix angelicae, the mint and the asarum are mutually cooperated during moxibustion so as to effectively treat allergic rhinitis of patients.

Proved by verification, the formula of the moxibustion strip or moxibustion column for treating allergic rhinitis has good and lasting curative effect on allergic rhinitis, small side effect, low cost and extremely wide application prospect.

Although specific embodiments of the present invention have been described above, it will be appreciated by those skilled in the art that these embodiments are merely illustrative and various changes or modifications may be made without departing from the principles and spirit of the invention.

Claims

1. A moxibustion strip or moxibustion column for treating allergic rhinitis is characterized by comprising the following components:

folium artemisiae argyi: 70-80 parts of,

And (3) snakegourd fruit: 5-8 parts of,

Fructus xanthil: 5-8 parts of,

Wind prevention: 3-5 parts of,

Radix angelicae: 3-5 parts of,

Mint: 1-3 parts of,

Asarum: 1-3 parts.

2. The moxibustion stick or column of claim 1, wherein the moxibustion stick is cylindrical, has a diameter of 18mm and a length of 200mm, and has a mass of 18-20 g/stick.

3. The moxibustion stick or column according to claim 1, wherein the moxibustion column is in the shape of a cone with a diameter of 15mm and a length of 40mm, and the mass of the moxibustion column is 1.8-2.1 g/column.