CN111686057A - Formula and preparation method of dendrobium officinale repair and isolation cream - Google Patents
Formula and preparation method of dendrobium officinale repair and isolation cream Download PDFInfo
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Abstract
The invention relates to a formula of a dendrobium officinale repair and isolation cream, which comprises the following components in percentage by weight: the phase A comprises the following components: 1-4% of cyclomethicone, 6000.5-3% of S-6000, 1-4% of liquid nonionic water-in-oil silicone emulsifier, 0.2-3% of phytosterol, 5-12% of mineral oil, 1-8% of C12-15 alcohol benzoate, 1-8% of isooctyl palmitate/ethylhexyl palmitate, 2-8% of titanium dioxide, 1-5% of neopentyl glycol diheptanoate and 0.5-3% of HV; the phase B comprises the following components: 0.5-3% of sodium chloride, 200.05-0.4% of polysorbate, 5-15% of glycerol, 3-9% of butanediol, 0.02-0.1% of sodium hyaluronate, 0.5-3% of a dendrobium officinale stem solution, 0.1-1% of sodium guaazulene sulfonate and the balance of water; the phase C comprises the following components: k3500.4-1%; its preparing process is also disclosed. The skin-care cream is mild in property, not greasy, easy to apply, free of pore blockage, free of toxic and side effects, has a certain repairing effect on skin, and meets the requirements of modern women on makeup and skin care.
Description
Technical Field
The invention relates to the technical field of cosmetics, in particular to a formula and a preparation method of dendrobium officinale repair and isolation cream.
Background
Ultraviolet rays, radiation, dust in the atmosphere and toxic and harmful substances in the air are the largest killers which harm the skin, so that the skin is aged, and the problems of color spots such as sunburn and the like appear on the face, and once the color spots are generated, the color spots are not easy to remove. Therefore, people are required to whiten and care skin and pay attention to the damage to the skin, so that a barrier cream is needed to play a role. The sun screen has the double effects of isolating ultraviolet rays and sun, can block damage of UVA and UVB to skin, prevents sunburn and suntan of the skin, and simultaneously isolates and lightens damage of external environment pollution to the skin. The existing sun screen basically has good moistening effect, but generally does not have the effect of repairing the skin, and is lack of enhancement of continuous nursing, nutrition supplementing and balancing functions of the face; meanwhile, the foundation cream realizes the effect of concealing and bottoming, and is easy to cause pore blockage and damage to skin due to overlarge oiliness. Therefore, it is necessary to develop a foundation cream with a repairing function, so that the foundation cream can be more firmly attached to the skin and the skin can be repaired.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provides a formula and a preparation method of dendrobium officinale repair and isolation cream.
The purpose of the invention is realized by the following technical scheme: the formula applied to the dendrobium officinale repair and isolation cream comprises the following components in percentage by weight:
the phase A comprises the following components: 1-4% of cyclomethicone, 6000.5-3% of S-6000, 1-4% of liquid nonionic water-in-oil silicone emulsifier, 0.2-3% of phytosterol, 5-12% of mineral oil, 1-8% of C12-15 alcohol benzoate, 1-8% of isooctyl palmitate/ethylhexyl palmitate, 2-8% of titanium dioxide, 1-5% of neopentyl glycol diheptanoate and 0.5-3% of HV;
the phase B comprises the following components: 0.5-3% of sodium chloride, 200.05-0.4% of polysorbate, 5-15% of glycerol, 3-9% of butanediol, 0.02-0.1% of sodium hyaluronate, 0.5-3% of a dendrobium officinale stem solution, 0.1-1% of sodium guaazulene sulfonate and the balance of water;
the phase C comprises the following components: k3500.4-1%.
Further, the formula applied to the dendrobium officinale repair and isolation cream comprises the following components in percentage by weight:
the phase A comprises the following components: 3% of cyclopolydimethylsiloxane, S-6001.5%, 2.8% of liquid nonionic water-in-oil silicone emulsifier, 0.5% of phytosterol, 8% of mineral oil, 4% of C12-15 alcohol benzoate, 5% of isooctyl palmitate/ethylhexyl palmitate, 5% of titanium dioxide, 2% of neopentyl glycol diheptanoate and HV 2%;
the phase B comprises the following components: 1.5% of sodium chloride, 200.2% of polysorbate, 10% of glycerin, 5% of butanediol, 0.05% of sodium hyaluronate, 2% of dendrobium officinale stem solution, 0.5% of guaiazulene sodium sulfonate and the balance of water;
the phase C comprises the following components: k3500.8 percent.
Further, the S-600 is a mixture of a polydimethylsiloxane/vinyl polydimethylsiloxane crosspolymer, laureth-3 and laureth-25.
Further, the liquid nonionic water-in-oil silicone emulsifier is one or more of cetyl polyethylene glycol, polypropylene glycol-10 and 1 dimethyl siloxane.
Further, the HV is a mixture of mineral oil, propylene carbonate and disteardimonium hectorite.
Further, the dendrobium officinale stem solution is a mixed solution of a dendrobium officinale stem extract, dipropylene glycol and water, wherein the weight of the dendrobium officinale stem extract accounts for 2% of the weight of the dendrobium officinale stem solution, the weight of the dipropylene glycol accounts for 10% of the weight of the dendrobium officinale stem solution, and the weight of the water accounts for 88% of the weight of the dendrobium officinale stem solution.
Further, the K350 is a mixture of phenoxyethanol, methylparaben, ethylparaben, ethylhexyl glycerol and propylene glycol, and the phenoxyethanol accounts for 50% of the weight of the K350, the methylparaben accounts for 15% of the weight of the K350, the ethylparaben accounts for 10% of the weight of the K350, the ethylhexyl accounts for 10% of the weight of the K350, and the propylene glycol accounts for 15% of the weight of the K350.
The preparation method of the dendrobium officinale repair and isolation cream comprises the following steps:
(1) pre-dispersing cyclopolydimethylsiloxane and S-600, adding the other components of the phase A, uniformly stirring, and homogenizing until fine particles do not exist for later use;
(2) pre-dispersing sodium hyaluronate and butanediol, adding the rest components of phase B, heating to 80 ℃, stirring until the components are completely dissolved, and cooling to normal temperature;
(3) slowly pumping the phase B component into the phase A component, stirring uniformly, and homogenizing for 3-5 min;
(4) adding the phase C component, and fully and uniformly stirring to obtain the repairing and isolating cream.
Further, the step (2) also comprises the preparation of dendrobium officinale stem solution, and the preparation method comprises the following steps:
a. cleaning a certain amount of fresh stem of herba Dendrobii, draining, and cutting into 3-5mm segments with a guillotine;
b. putting the cut dendrobium into a container, adding an extraction solvent, wherein the weight ratio of the feed liquid is 1:5, and the extraction solvent is 30% alcohol;
c. stirring during leaching, wherein the leaching temperature is 75 ℃, and the temperature is reduced after the leaching time is 2 hours;
d. cooling to 50 deg.C, filtering while hot, and filtering with 400 mesh gauze;
e. continuously cooling the filtrate to 45 ℃, adding a certain amount of preservative, uniformly stirring, and standing for 48 hours;
f. taking the supernatant after standing, filtering again, and using a 10-inch folding filter element with the size less than 1 mu m;
g. concentrating the obtained filtrate under reduced pressure to obtain 1/4 concentrated solution;
h. adding dipropylene glycol into the concentrated solution to prepare a dendrobium officinale stem solution with the effective substance content of 2%.
The invention has the following advantages:
1. the repair and isolation cream disclosed by the invention is prepared by compounding titanium dioxide with a natural active ingredient, namely dendrobium officinale stem extract, phytosterol, sodium guaiazulene sulfonate and the like, and further adding auxiliary ingredients, namely HV, cetyl polyethylene glycol/polypropylene glycol-10/1 dimethyl siloxane, polysorbate-20, sodium hyaluronate and the like, so that the stability of the natural active ingredient in a system can be improved, the prepared isolation cream is easy to coat, mild and skin-friendly, and does not cause any discomfort.
2. The amino acid components in the dendrobium officinale stem extract can improve the water content of human skin, are easy to be absorbed by the skin, are important nutrient components in the skin, and the leucine contained in the extract can reduce the hardness of the skin, improve the skin barrier, accelerate the metabolism of skin cells, promote the regeneration and healing of skin tissues and repair the skin.
3. The guaiazulene sodium sulfonate is a synthetic of natural plant extracts, has high safety, is derived from chamomile and chamomile, has definite anti-inflammatory and anti-allergic effects and tissue repair effects, and stimulates the formation of granulation and epithelial tissues.
4. The repair make-up base cream provided by the invention is mild in property, not greasy, easy to apply, free of pore blockage, free of toxic and side effects, has a certain repair effect on skin, simple in preparation method and stable in process, and particularly meets the requirements of modern women on make-up and skin care.
Detailed Description
The invention is further described below with reference to examples, but the scope of the invention is not limited to the following.
[ example 1 ]:
the formula applied to the dendrobium officinale repair and isolation cream comprises the following components in percentage by weight:
the phase A comprises the following components: 4% of cyclopolydimethylsiloxane, 4% of S-6000.5%, 4% of a liquid nonionic water-in-oil silicone emulsifier, 0.2% of phytosterol, 12% of mineral oil, 1% of C12-15 alcohol benzoate, 8% of isooctyl palmitate/ethylhexyl palmitate, 2% of titanium dioxide, 5% of neopentyl glycol diheptanoate and 0.5% of HV;
the phase B comprises the following components: 3% of sodium chloride, 200.05% of polysorbate, 15% of glycerol, 3% of butanediol, 0.1% of sodium hyaluronate, 0.5% of dendrobium officinale stem solution, 1% of guaiazulene sodium sulfonate and the balance of water;
the phase C comprises the following components: k3500.4 percent.
Further, the S-600 is a mixture of a polydimethylsiloxane/vinyl polydimethylsiloxane crosspolymer, laureth-3 and laureth-25.
Further, the liquid nonionic water-in-oil silicone emulsifier is one or more of cetyl polyethylene glycol, polypropylene glycol-10 and 1 dimethyl siloxane.
Further, the HV is a mixture of mineral oil, propylene carbonate and disteardimonium hectorite.
Further, the dendrobium officinale stem solution is a mixed solution of a dendrobium officinale stem extract, dipropylene glycol and water, wherein the weight of the dendrobium officinale stem extract accounts for 2% of the weight of the dendrobium officinale stem solution, the weight of the dipropylene glycol accounts for 10% of the weight of the dendrobium officinale stem solution, and the weight of the water accounts for 88% of the weight of the dendrobium officinale stem solution.
Further, the K350 is a mixture of phenoxyethanol, methylparaben, ethylparaben, ethylhexyl glycerol and propylene glycol, and the phenoxyethanol accounts for 50% of the weight of the K350, the methylparaben accounts for 15% of the weight of the K350, the ethylparaben accounts for 10% of the weight of the K350, the ethylhexyl accounts for 10% of the weight of the K350, and the propylene glycol accounts for 15% of the weight of the K350.
The preparation method of the dendrobium officinale repair and isolation cream comprises the following steps:
(1) pre-dispersing cyclopolydimethylsiloxane and S-600, adding the other components of the phase A, uniformly stirring, and homogenizing until fine particles do not exist for later use;
(2) pre-dispersing sodium hyaluronate and butanediol, adding the rest components of phase B, heating to 80 ℃, stirring until the components are completely dissolved, and cooling to normal temperature;
(3) slowly pumping the phase B component into the phase A component, stirring uniformly, and homogenizing for 3 min;
(4) adding the phase C component, and fully and uniformly stirring to obtain the repairing and isolating cream.
Further, the step (2) also comprises the preparation of dendrobium officinale stem solution, and the preparation method comprises the following steps:
a. cleaning a certain amount of fresh stem of herba Dendrobii, draining, and cutting into 5mm segments with a guillotine;
b. putting the cut dendrobium into a container, adding an extraction solvent, wherein the weight ratio of the feed liquid is 1:5, and the extraction solvent is 30% alcohol;
c. stirring during leaching, wherein the leaching temperature is 75 ℃, and the temperature is reduced after the leaching time is 2 hours;
d. cooling to 50 deg.C, filtering while hot, and filtering with 400 mesh gauze;
e. continuously cooling the filtrate to 45 ℃, adding a certain amount of preservative, uniformly stirring, and standing for 48 hours;
f. taking the supernatant after standing, filtering again, and using a 10-inch folding filter element with the size less than 1 mu m;
g. concentrating the obtained filtrate under reduced pressure to obtain 1/4 concentrated solution;
h. adding dipropylene glycol into the concentrated solution to prepare a dendrobium officinale stem solution with the effective substance content of 2%.
[ example 2 ]:
the formula applied to the dendrobium officinale repair and isolation cream comprises the following components in percentage by weight:
the phase A comprises the following components: 3% of cyclopolydimethylsiloxane, S-6001.5%, 2.8% of liquid nonionic water-in-oil silicone emulsifier, 0.5% of phytosterol, 8% of mineral oil, 4% of C12-15 alcohol benzoate, 5% of isooctyl palmitate/ethylhexyl palmitate, 5% of titanium dioxide, 2% of neopentyl glycol diheptanoate and HV 2%;
the phase B comprises the following components: 1.5% of sodium chloride, 200.2% of polysorbate, 10% of glycerin, 5% of butanediol, 0.05% of sodium hyaluronate, 2% of dendrobium officinale stem solution, 0.5% of guaiazulene sodium sulfonate and the balance of water;
the phase C comprises the following components: k3500.8 percent.
Further, the S-600 is a mixture of a polydimethylsiloxane/vinyl polydimethylsiloxane crosspolymer, laureth-3 and laureth-25.
Further, the liquid nonionic water-in-oil silicone emulsifier is one or more of cetyl polyethylene glycol, polypropylene glycol-10 and 1 dimethyl siloxane.
Further, the HV is a mixture of mineral oil, propylene carbonate and disteardimonium hectorite.
Further, the dendrobium officinale stem solution is a mixed solution of a dendrobium officinale stem extract, dipropylene glycol and water, wherein the weight of the dendrobium officinale stem extract accounts for 2% of the weight of the dendrobium officinale stem solution, the weight of the dipropylene glycol accounts for 10% of the weight of the dendrobium officinale stem solution, and the weight of the water accounts for 88% of the weight of the dendrobium officinale stem solution.
Further, the K350 is a mixture of phenoxyethanol, methylparaben, ethylparaben, ethylhexyl glycerol and propylene glycol, and the phenoxyethanol accounts for 50% of the weight of the K350, the methylparaben accounts for 15% of the weight of the K350, the ethylparaben accounts for 10% of the weight of the K350, the ethylhexyl accounts for 10% of the weight of the K350, and the propylene glycol accounts for 15% of the weight of the K350.
The preparation method of the dendrobium officinale repair and isolation cream comprises the following steps:
(1) pre-dispersing cyclopolydimethylsiloxane and S-600, adding the other components of the phase A, uniformly stirring, and homogenizing until fine particles do not exist for later use;
(2) pre-dispersing sodium hyaluronate and butanediol, adding the rest components of phase B, heating to 80 ℃, stirring until the components are completely dissolved, and cooling to normal temperature;
(3) slowly pumping the phase B component into the phase A component, stirring uniformly, and homogenizing for 4 min;
(4) adding the phase C component, and fully and uniformly stirring to obtain the repairing and isolating cream.
Further, the step (2) also comprises the preparation of dendrobium officinale stem solution, and the preparation method comprises the following steps:
a. cleaning a certain amount of fresh stem of herba Dendrobii, draining, and cutting into 4mm segments with a guillotine;
b. putting the cut dendrobium into a container, adding an extraction solvent, wherein the weight ratio of the feed liquid is 1:5, and the extraction solvent is 30% alcohol;
c. stirring during leaching, wherein the leaching temperature is 75 ℃, and the temperature is reduced after the leaching time is 2 hours;
d. cooling to 50 deg.C, filtering while hot, and filtering with 400 mesh gauze;
e. continuously cooling the filtrate to 45 ℃, adding a certain amount of preservative, uniformly stirring, and standing for 48 hours;
f. taking the supernatant after standing, filtering again, and using a 10-inch folding filter element with the size less than 1 mu m;
g. concentrating the obtained filtrate under reduced pressure to obtain 1/4 concentrated solution;
h. adding dipropylene glycol into the concentrated solution to prepare a dendrobium officinale stem solution with the effective substance content of 2%.
[ example 3 ]:
the formula applied to the dendrobium officinale repair and isolation cream comprises the following components in percentage by weight:
the phase A comprises the following components: 2% of cyclopolydimethylsiloxane, 2% of S-6002%, 2% of a liquid nonionic water-in-oil silicone emulsifier, 2% of phytosterol, 8% of mineral oil, 5% of C12-15 alcohol benzoate, 4% of isooctyl palmitate/ethylhexyl palmitate, 4% of titanium dioxide, 2% of neopentyl glycol diheptanoate and 1% of HV;
the phase B comprises the following components: 1.8% of sodium chloride, 200.3% of polysorbate, 9% of glycerol, 7% of butanediol, 0.04% of sodium hyaluronate, 2% of dendrobium officinale stem solution, 0.6% of guaiazulene sodium sulfonate and the balance of water;
the phase C comprises the following components: k3500.7 percent.
Further, the S-600 is a mixture of a polydimethylsiloxane/vinyl polydimethylsiloxane crosspolymer, laureth-3 and laureth-25.
Further, the liquid nonionic water-in-oil silicone emulsifier is one or more of cetyl polyethylene glycol, polypropylene glycol-10 and 1 dimethyl siloxane.
Further, the HV is a mixture of mineral oil, propylene carbonate and disteardimonium hectorite.
Further, the dendrobium officinale stem solution is a mixed solution of a dendrobium officinale stem extract, dipropylene glycol and water, wherein the weight of the dendrobium officinale stem extract accounts for 2% of the weight of the dendrobium officinale stem solution, the weight of the dipropylene glycol accounts for 10% of the weight of the dendrobium officinale stem solution, and the weight of the water accounts for 88% of the weight of the dendrobium officinale stem solution.
Further, the K350 is a mixture of phenoxyethanol, methylparaben, ethylparaben, ethylhexyl glycerol and propylene glycol, and the phenoxyethanol accounts for 50% of the weight of the K350, the methylparaben accounts for 15% of the weight of the K350, the ethylparaben accounts for 10% of the weight of the K350, the ethylhexyl accounts for 10% of the weight of the K350, and the propylene glycol accounts for 15% of the weight of the K350.
The preparation method of the dendrobium officinale repair and isolation cream comprises the following steps:
(1) pre-dispersing cyclopolydimethylsiloxane and S-600, adding the other components of the phase A, uniformly stirring, and homogenizing until fine particles do not exist for later use;
(2) pre-dispersing sodium hyaluronate and butanediol, adding the rest components of phase B, heating to 80 ℃, stirring until the components are completely dissolved, and cooling to normal temperature;
(3) slowly pumping the phase B component into the phase A component, stirring uniformly, and homogenizing for 3.5 min;
(4) adding the phase C component, and fully and uniformly stirring to obtain the repairing and isolating cream.
Further, the step (2) also comprises the preparation of dendrobium officinale stem solution, and the preparation method comprises the following steps:
a. cleaning a certain amount of fresh stem of herba Dendrobii, draining, and cutting into 4.5mm segments with a guillotine;
b. putting the cut dendrobium into a container, adding an extraction solvent, wherein the weight ratio of the feed liquid is 1:5, and the extraction solvent is 30% alcohol;
c. stirring during leaching, wherein the leaching temperature is 75 ℃, and the temperature is reduced after the leaching time is 2 hours;
d. cooling to 50 deg.C, filtering while hot, and filtering with 400 mesh gauze;
e. continuously cooling the filtrate to 45 ℃, adding a certain amount of preservative, uniformly stirring, and standing for 48 hours;
f. taking the supernatant after standing, filtering again, and using a 10-inch folding filter element with the size less than 1 mu m;
g. concentrating the obtained filtrate under reduced pressure to obtain 1/4 concentrated solution;
h. adding dipropylene glycol into the concentrated solution to prepare a dendrobium officinale stem solution with the effective substance content of 2%.
Example 4:
the formula applied to the dendrobium officinale repair and isolation cream comprises the following components in percentage by weight:
the phase A comprises the following components: 1% of cyclomethicone, S-6003%, 1% of liquid nonionic water-in-oil silicone emulsifier, 3% of phytosterol, 5% of mineral oil, 8% of C12-15 alcohol benzoate, 1% of isooctyl palmitate/ethylhexyl palmitate, 8% of titanium dioxide, 1% of neopentyl glycol diheptanoate and 3% of HV;
the phase B comprises the following components: 0.5% of sodium chloride, 200.4% of polysorbate, 5% of glycerin, 9% of butanediol, 0.02% of sodium hyaluronate, 3% of dendrobium officinale stem solution, 0.1% of guaiazulene sodium sulfonate and the balance of water;
the phase C comprises the following components: and K3501%.
Further, the S-600 is a mixture of a polydimethylsiloxane/vinyl polydimethylsiloxane crosspolymer, laureth-3 and laureth-25.
Further, the liquid nonionic water-in-oil silicone emulsifier is one or more of cetyl polyethylene glycol, polypropylene glycol-10 and 1 dimethyl siloxane.
Further, the HV is a mixture of mineral oil, propylene carbonate and disteardimonium hectorite.
Further, the dendrobium officinale stem solution is a mixed solution of a dendrobium officinale stem extract, dipropylene glycol and water, wherein the weight of the dendrobium officinale stem extract accounts for 2% of the weight of the dendrobium officinale stem solution, the weight of the dipropylene glycol accounts for 10% of the weight of the dendrobium officinale stem solution, and the weight of the water accounts for 88% of the weight of the dendrobium officinale stem solution.
Further, the K350 is a mixture of phenoxyethanol, methylparaben, ethylparaben, ethylhexyl glycerol and propylene glycol, and the phenoxyethanol accounts for 50% of the weight of the K350, the methylparaben accounts for 15% of the weight of the K350, the ethylparaben accounts for 10% of the weight of the K350, the ethylhexyl accounts for 10% of the weight of the K350, and the propylene glycol accounts for 15% of the weight of the K350.
The preparation method of the dendrobium officinale repair and isolation cream comprises the following steps:
(1) pre-dispersing cyclopolydimethylsiloxane and S-600, adding the other components of the phase A, uniformly stirring, and homogenizing until fine particles do not exist for later use;
(2) pre-dispersing sodium hyaluronate and butanediol, adding the rest components of phase B, heating to 80 ℃, stirring until the components are completely dissolved, and cooling to normal temperature;
(3) slowly pumping the phase B component into the phase A component, stirring uniformly, and homogenizing for 5 min;
(4) adding the phase C component, and fully and uniformly stirring to obtain the repairing and isolating cream.
Further, the step (2) also comprises the preparation of dendrobium officinale stem solution, and the preparation method comprises the following steps:
a. cleaning a certain amount of fresh stem of herba Dendrobii, draining, and cutting into 3mm segments with a guillotine;
b. putting the cut dendrobium into a container, adding an extraction solvent, wherein the weight ratio of the feed liquid is 1:5, and the extraction solvent is 30% alcohol;
c. stirring during leaching, wherein the leaching temperature is 75 ℃, and the temperature is reduced after the leaching time is 2 hours;
d. cooling to 50 deg.C, filtering while hot, and filtering with 400 mesh gauze;
e. continuously cooling the filtrate to 45 ℃, adding a certain amount of preservative, uniformly stirring, and standing for 48 hours;
f. taking the supernatant after standing, filtering again, and using a 10-inch folding filter element with the size less than 1 mu m;
g. concentrating the obtained filtrate under reduced pressure to obtain 1/4 concentrated solution;
h. adding dipropylene glycol into the concentrated solution to prepare a dendrobium officinale stem solution with the effective substance content of 2%.
Comparative example 1
The difference from example 2 is that HV was not added.
Comparative example 2
The difference from the example 2 is that the dendrobium officinale stem solution is not added.
Comparative example 3
The difference from the example 2 is that the dendrobium officinale stem extract and the guaiazulene sodium sulfonate are not added.
Some performance index tests were performed on the test products as follows:
1. appearance: fine cream
2. Heat resistance stability test (48 ℃ X24h) qualification
3. Cold stability test (-15 ℃ X24h): qualified
Test example I, patch test on human skin
The repairing and isolating creams prepared in the examples 1-4 and the comparative examples 1-3 of the invention are tested according to related requirements and determination methods of a human skin patch test in 2015 edition of cosmetic hygiene Specification issued by Ministry of health, skin reactions are observed at 0h, 6h, 12h, 24h and 48h respectively, the experimental results of all volunteer subjects are negative results, and no adverse skin reaction occurs. The repairing and isolating cream provided by the invention is free of irritation and high in safety.
Test example two, test of Using Effect of repairing base cream
Testing the population: office professional women 70 with the age of 25-40 years are used as volunteer subjects, the volunteer subjects are randomly divided into 7 groups, namely, groups of examples 1-4 and groups of comparative examples 1-3, the groups of examples 1-4 use the repair base creams prepared in the groups of examples 1-4, the groups of comparative examples 1-3 use the repair base creams prepared in the groups of comparative examples 1-3, and the repair base creams are continuously used for one month, and sensory use conditions and use feelings of the volunteer subjects are counted after the test is completed.
Standard table for sense experience
The results of sensory evaluation of the compositions of the base creams are averaged and shown in the following table:
as shown in the table, the repairing and sun screen cream prepared by the invention has the advantages of good smearing performance, good skin feeling, good removal performance, no damage to skin, no stimulation and obviously better comprehensive performance than a comparative example.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (9)
1. The formula applied to the dendrobium officinale repair and isolation cream is characterized in that: comprises the following components in percentage by weight:
the phase A comprises the following components: 1-4% of cyclomethicone, 6000.5-3% of S-6000, 1-4% of liquid nonionic water-in-oil silicone emulsifier, 0.2-3% of phytosterol, 5-12% of mineral oil, 1-8% of C12-15 alcohol benzoate, 1-8% of isooctyl palmitate/ethylhexyl palmitate, 2-8% of titanium dioxide, 1-5% of neopentyl glycol diheptanoate and 0.5-3% of HV;
the phase B comprises the following components: 0.5-3% of sodium chloride, 200.05-0.4% of polysorbate, 5-15% of glycerol, 3-9% of butanediol, 0.02-0.1% of sodium hyaluronate, 0.5-3% of a dendrobium officinale stem solution, 0.1-1% of sodium guaazulene sulfonate and the balance of water;
the phase C comprises the following components: k3500.4-1%.
2. The formula of the dendrobium officinale repair and sun screen cream as claimed in claim 1, wherein the formula comprises the following components: comprises the following components in percentage by weight:
the phase A comprises the following components: 3% of cyclopolydimethylsiloxane, S-6001.5%, 2.8% of liquid nonionic water-in-oil silicone emulsifier, 0.5% of phytosterol, 8% of mineral oil, 4% of C12-15 alcohol benzoate, 5% of isooctyl palmitate/ethylhexyl palmitate, 5% of titanium dioxide, 2% of neopentyl glycol diheptanoate and HV 2%;
the phase B comprises the following components: 1.5% of sodium chloride, 200.2% of polysorbate, 10% of glycerin, 5% of butanediol, 0.05% of sodium hyaluronate, 2% of dendrobium officinale stem solution, 0.5% of guaiazulene sodium sulfonate and the balance of water;
the phase C comprises the following components: k3500.8 percent.
3. The formula of the dendrobium officinale repair and sun screen as claimed in claim 1 or 2, wherein the formula comprises the following components: the S-600 is a mixture of polydimethylsiloxane/vinyl polydimethylsiloxane crosspolymer, laureth-3 and laureth-25.
4. The formula of the dendrobium officinale repair and sun screen as claimed in claim 1 or 2, wherein the formula comprises the following components: the liquid nonionic water-in-oil silicone emulsifier is one or more of cetyl polyethylene glycol, polypropylene glycol-10 and 1 dimethyl siloxane.
5. The formula of the dendrobium officinale repair and sun screen as claimed in claim 1 or 2, wherein the formula comprises the following components: the HV is a mixture of mineral oil, propylene carbonate and disteardimonium hectorite.
6. The formula of the dendrobium officinale repair and sun screen as claimed in claim 1 or 2, wherein the formula comprises the following components: the dendrobium officinale stem solution is a mixed solution of a dendrobium officinale stem extract, dipropylene glycol and water, wherein the weight of the dendrobium officinale stem extract accounts for 2% of the weight of the dendrobium officinale stem solution, the weight of the dipropylene glycol accounts for 10% of the weight of the dendrobium officinale stem solution, and the weight of the water accounts for 88% of the weight of the dendrobium officinale stem solution.
7. The formula of the dendrobium officinale repair and sun screen as claimed in claim 1 or 2, wherein the formula comprises the following components: the K350 is a mixture of phenoxyethanol, methyl hydroxybenzoate, ethylparaben, ethylhexylglycerin and propylene glycol, the weight of the phenoxyethanol accounts for 50% of the weight of the K350, the weight of the methyl hydroxybenzoate accounts for 15% of the weight of the K350, the weight of the ethylparaben accounts for 10% of the weight of the K350, the weight of the ethylhexyl accounts for 10% of the weight of the K350, and the weight of the propylene glycol accounts for 15% of the weight of the K350.
8. The preparation method of the dendrobium officinale repair and isolation cream as claimed in any one of claims 1 to 7, wherein the preparation method comprises the following steps: the method comprises the following steps:
(1) pre-dispersing cyclopolydimethylsiloxane and S-600, adding the other components of the phase A, uniformly stirring, and homogenizing until fine particles do not exist for later use;
(2) pre-dispersing sodium hyaluronate and butanediol, adding the rest components of phase B, heating to 80 ℃, stirring until the components are completely dissolved, and cooling to normal temperature;
(3) slowly pumping the phase B component into the phase A component, stirring uniformly, and homogenizing for 3-5 min;
(4) adding the phase C component, and fully and uniformly stirring to obtain the repairing and isolating cream.
9. The preparation method of the dendrobium officinale repair and sun screen cream according to claim 8, wherein the preparation method comprises the following steps: in the step (2), the preparation method also comprises the preparation of the dendrobium officinale stem solution, and the preparation method comprises the following steps:
a. cleaning a certain amount of fresh stem of herba Dendrobii, draining, and cutting into 3-5mm segments with a guillotine;
b. putting the cut dendrobium into a container, adding an extraction solvent, wherein the weight ratio of the feed liquid is 1:5, and the extraction solvent is 30% alcohol;
c. stirring during leaching, wherein the leaching temperature is 75 ℃, and the temperature is reduced after the leaching time is 2 hours;
d. cooling to 50 deg.C, filtering while hot, and filtering with 400 mesh gauze;
e. continuously cooling the filtrate to 45 ℃, adding a certain amount of preservative, uniformly stirring, and standing for 48 hours;
f. taking the supernatant after standing, filtering again, and using a 10-inch folding filter element with the size less than 1 mu m;
g. concentrating the obtained filtrate under reduced pressure to obtain 1/4 concentrated solution;
h. adding dipropylene glycol into the concentrated solution to prepare a dendrobium officinale stem solution with the effective substance content of 2%.
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Application publication date: 20200922 |