CN111685937A - Hemostatic and bactericidal medical dressing and preparation method thereof - Google Patents
Hemostatic and bactericidal medical dressing and preparation method thereof Download PDFInfo
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- CN111685937A CN111685937A CN202010579996.1A CN202010579996A CN111685937A CN 111685937 A CN111685937 A CN 111685937A CN 202010579996 A CN202010579996 A CN 202010579996A CN 111685937 A CN111685937 A CN 111685937A
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- hemostatic
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- thermoplastic elastomer
- textile material
- material layer
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- 230000002439 hemostatic effect Effects 0.000 title claims abstract description 57
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 50
- 238000002360 preparation method Methods 0.000 title claims abstract description 13
- 239000010410 layer Substances 0.000 claims abstract description 122
- 229920002725 thermoplastic elastomer Polymers 0.000 claims abstract description 66
- 229920002678 cellulose Polymers 0.000 claims abstract description 59
- 239000001913 cellulose Substances 0.000 claims abstract description 59
- 239000000843 powder Substances 0.000 claims abstract description 30
- 229920000642 polymer Polymers 0.000 claims abstract description 23
- 239000011247 coating layer Substances 0.000 claims abstract description 19
- 150000004676 glycans Chemical class 0.000 claims abstract description 9
- 239000002245 particle Substances 0.000 claims abstract description 9
- 229920001282 polysaccharide Polymers 0.000 claims abstract description 9
- 239000005017 polysaccharide Substances 0.000 claims abstract description 9
- 239000002344 surface layer Substances 0.000 claims abstract description 8
- 239000000463 material Substances 0.000 claims description 57
- 239000004753 textile Substances 0.000 claims description 56
- 238000000034 method Methods 0.000 claims description 19
- 239000000835 fiber Substances 0.000 claims description 14
- 238000002844 melting Methods 0.000 claims description 14
- 230000008018 melting Effects 0.000 claims description 14
- 239000004332 silver Substances 0.000 claims description 14
- 229910052709 silver Inorganic materials 0.000 claims description 14
- -1 silver ions Chemical class 0.000 claims description 14
- FOIXSVOLVBLSDH-UHFFFAOYSA-N Silver ion Chemical compound [Ag+] FOIXSVOLVBLSDH-UHFFFAOYSA-N 0.000 claims description 8
- 239000003899 bactericide agent Substances 0.000 claims description 8
- 239000011248 coating agent Substances 0.000 claims description 4
- 238000000576 coating method Methods 0.000 claims description 4
- 230000023597 hemostasis Effects 0.000 claims description 4
- 238000005213 imbibition Methods 0.000 claims description 4
- 230000001954 sterilising effect Effects 0.000 claims description 3
- 238000004659 sterilization and disinfection Methods 0.000 claims description 3
- 239000007788 liquid Substances 0.000 abstract description 13
- 238000010521 absorption reaction Methods 0.000 abstract description 6
- 230000007547 defect Effects 0.000 abstract description 5
- 238000005470 impregnation Methods 0.000 abstract description 3
- 208000027418 Wounds and injury Diseases 0.000 description 20
- 206010052428 Wound Diseases 0.000 description 19
- 230000006378 damage Effects 0.000 description 6
- 230000008569 process Effects 0.000 description 5
- 206010011409 Cross infection Diseases 0.000 description 3
- 206010029803 Nosocomial infection Diseases 0.000 description 3
- 208000004210 Pressure Ulcer Diseases 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 244000005700 microbiome Species 0.000 description 3
- 230000035699 permeability Effects 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 230000004520 agglutination Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000029663 wound healing Effects 0.000 description 2
- 241000228212 Aspergillus Species 0.000 description 1
- 241000222122 Candida albicans Species 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 239000001888 Peptone Substances 0.000 description 1
- 108010080698 Peptones Proteins 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 229940095731 candida albicans Drugs 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000000416 exudates and transudate Anatomy 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 230000007310 pathophysiology Effects 0.000 description 1
- 235000019319 peptone Nutrition 0.000 description 1
- 210000005259 peripheral blood Anatomy 0.000 description 1
- 239000011886 peripheral blood Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
Classifications
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- A61F13/01029—
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/00051—Accessories for dressings
- A61F13/00063—Accessories for dressings comprising medicaments or additives, e.g. odor control, PH control, debriding, antimicrobic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/00987—Apparatus or processes for manufacturing non-adhesive dressings or bandages
- A61F13/00991—Apparatus or processes for manufacturing non-adhesive dressings or bandages for treating webs, e.g. for moisturising, coating, impregnating or applying powder
-
- A61F13/01042—
-
- A61F13/01046—
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F2013/00361—Plasters
- A61F2013/00365—Plasters use
- A61F2013/00463—Plasters use haemostatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F2013/00361—Plasters
- A61F2013/00727—Plasters means for wound humidity control
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F2013/00361—Plasters
- A61F2013/00902—Plasters containing means
- A61F2013/0091—Plasters containing means with disinfecting or anaesthetics means, e.g. anti-mycrobic
Abstract
The invention relates to the technical field of medical dressings, in particular to a hemostatic and bactericidal medical dressing and a preparation method thereof, wherein the hemostatic and bactericidal medical dressing comprises a polymer coating layer, a liquid absorbing area is arranged on the inner surface layer of the polymer coating layer, the liquid absorbing area is composed of a plurality of columnar bulges, the top surfaces of the columnar bulges are arc-shaped, a plurality of grooves are formed in the surfaces of the columnar bulges, and hemostatic powder is filled in the grooves; the invention adopts the technical scheme that the columnar bulges of the thermoplastic elastomer cellulose layer are filled with the hemostatic powder, and the hemostatic powder adopts microporous polysaccharide particles, so that the defects of poor liquid absorption capacity, relatively high cost and high skin impregnation probability around the wound surface of the polymeric film dressing are overcome.
Description
Technical Field
The invention relates to the technical field of medical dressings, in particular to a hemostatic and bactericidal medical dressing and a preparation method thereof.
Background
Medical dressings are wound covering articles used to cover sores, wounds, or other damaged medical materials. With the intensive research on the pathophysiology of the wound healing process, people understand the wound healing process more and more deeply, thereby leading to the continuous improvement and development of medical wound dressings.
The natural gauze has strong performance of quickly absorbing wound exudate, and the production and processing process is simpler, but the natural gauze also has the following defects: the permeability is too high, so that the wound surface is easy to dehydrate and adhere to the wound surface, secondary mechanical damage can be caused during replacement, external environment microorganisms can easily pass through the wound surface, the probability of cross infection is high, the dosage is large, the replacement is frequent and troublesome, and the pain of a patient is easily increased.
The polymeric membrane dressing has the characteristics that gases such as oxygen, water vapor and the like can be freely transparent, and granular foreign matters in the environment cannot pass through, microorganisms in the environment are blocked outside the wound surface, cross infection can be prevented, the moisture retention is realized, the wound surface is kept moist, secondary mechanical damage cannot be caused during replacement, the material is transparent, the wound surface condition can be observed conveniently, however, the liquid absorption capacity is poor, the cost is relatively high, and the skin impregnation probability around the wound surface is high.
Disclosure of Invention
The purpose of the invention is: overcomes the defects in the prior art, and provides the hemostatic and bactericidal medical dressing which has good liquid absorbability and strong air permeability, and can not cause secondary mechanical injury in the replacement process.
In order to solve the technical problems, the technical scheme adopted by the invention is as follows:
the utility model provides a medical dressing that disinfects stanchs, includes the polymer coating, be provided with the imbibition district on the inner surface layer of polymer coating, the imbibition district comprises a plurality of column archs, the bellied top surface of column is the arc, the bellied surface of column has a plurality of recesses, the recess intussuseption is filled with hemostasis powder.
Further, the polymer coating layer comprises a plane textile material layer and a thermoplastic elastomer cellulose layer located on the plane textile material layer, silver ion bactericides are sprayed on the thermoplastic elastomer cellulose layer, a plurality of columnar protrusions are arranged on the thermoplastic elastomer cellulose layer, the plane textile material layer and the thermoplastic elastomer cellulose layer are connected through a hot melting method, and the thermoplastic elastomer cellulose layer and the columnar protrusions are of an integral structure.
Further, the thermoplastic elastomer cellulose layer covers 30-40% of the area of the plane textile material layer and is positioned at the center of the plane textile material layer.
Furthermore, the plane textile material layer is made of antibacterial fibers containing silver ions.
Furthermore, the inner wall of the groove is arc-shaped, a bump is arranged at the bottom of the groove, and the cross section of the groove is circular.
Further, the diameter to depth ratio of the groove is (3:1) - (2:1), and the height of the bump is half of the depth of the groove.
Furthermore, the hemostatic powder is microporous polysaccharide particles.
Further, the height of the columnar bulge is 0.1-0.2 mm.
Another object of the invention is: provides a preparation method of the hemostatic and bactericidal medical dressing with simple production process and low production cost.
In order to solve the technical problems, the technical scheme adopted by the invention is as follows:
a preparation method of a medical dressing for hemostasis and sterilization comprises the following steps:
(1) selecting antibacterial fiber containing silver ions to prepare a plane textile material layer;
(2) preparing a thermoplastic elastomer cellulosic layer;
(3) connecting the plane textile material layer and the thermoplastic elastomer cellulose layer by a hot melting method;
(4) hemostatic powder is filled in the grooves of the columnar bulges of the thermoplastic elastomer cellulose layer.
The technical scheme adopted by the invention has the beneficial effects that:
according to the hemostatic and bactericidal medical dressing, the columnar protrusions are arranged, the grooves are formed in the surface of the columnar protrusions, and the grooves are filled with hemostatic powder, so that the contact area between the dressing and a wound surface is reduced, the risk of secondary mechanical damage during replacement is reduced, meanwhile, the hemostatic powder in the grooves can quickly absorb moisture, and the hemostatic powder has a very high absorption effect on liquid, so that the adsorption of component moisture in blood causes the concentration of platelets, and the agglutination speed and the agglutination capacity of the hemostatic powder are enhanced; the quick water absorption effect also reduces the liquid volume of the wound part, which is beneficial to the occurrence of aggregation, and the silver ion bactericide is sprayed on the thermoplastic elastomer cellulose layer, thereby improving the sterilization performance of the dressing, overcoming the defects of too high permeability of natural gauze in the prior art, easy dehydration of the wound surface, easy adhesion to the wound surface, secondary mechanical damage caused during replacement, easy passing of external environment microorganisms, high probability of cross infection, more dosage, frequent and troublesome replacement, easy increase of the pain of patients, and certain pressure of the columnar bulge to peripheral blood vessels to promote hemostasis, and the waterproof gel is formed after water absorption to block the wound.
The invention adopts the technical scheme that the columnar bulges of the thermoplastic elastomer cellulose layer are filled with the hemostatic powder, and the hemostatic powder adopts microporous polysaccharide particles, so that the defects of poor liquid absorption capacity, relatively high cost and high skin impregnation probability around the wound surface of the polymeric film dressing are overcome.
Detailed Description
The following examples are intended to provide those skilled in the art with a more complete understanding of the present invention, and are not intended to limit the scope of the present invention. Reference herein to "one embodiment" or "an embodiment" means that a particular feature, structure, or characteristic may be included in at least one implementation of the invention. The appearances of the phrase "in one embodiment" in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments.
Example 1
A hemostatic and bactericidal medical dressing comprises a polymer coating layer, wherein a liquid absorbing area is arranged on the inner surface layer of the polymer coating layer and is composed of a plurality of columnar protrusions, the top surfaces of the columnar protrusions are arc-shaped, a plurality of grooves are formed in the surfaces of the columnar protrusions, hemostatic powder is filled in the grooves, the inner walls of the grooves are arc-shaped, a convex block is arranged at the bottom of each groove, the cross section of each groove is circular, the depth ratio of the diameter of each groove to the depth of each groove is 3:1, the height of each convex block is half of the depth of each groove, the hemostatic powder is microporous polysaccharide particles, and the height of each columnar protrusion is 0.1 mm.
The polymer coating layer comprises a plane textile material layer and a thermoplastic elastomer cellulose layer located on the plane textile material layer, a silver ion bactericide is sprayed on the thermoplastic elastomer cellulose layer, a plurality of columnar protrusions are arranged on the thermoplastic elastomer cellulose layer, the plane textile material layer is connected with the thermoplastic elastomer cellulose layer through a hot melting method, and the thermoplastic elastomer cellulose layer and the columnar protrusions are of an integral structure. The thermoplastic elastomer cellulose layer covers 30% of the area of the plane textile material layer and is positioned at the center of the plane textile material layer, and the plane textile material layer is made of antibacterial fiber containing silver ions.
The preparation method of the hemostatic and bactericidal medical dressing comprises the following steps:
(1) selecting antibacterial fiber containing silver ions to prepare a plane textile material layer;
(2) preparing a thermoplastic elastomer cellulosic layer;
(3) connecting the plane textile material layer and the thermoplastic elastomer cellulose layer by a hot melting method;
(4) hemostatic powder is filled in the grooves of the columnar bulges of the thermoplastic elastomer cellulose layer.
Example 2
A hemostatic and bactericidal medical dressing comprises a polymer coating layer, wherein a liquid absorbing area is arranged on the inner surface layer of the polymer coating layer and is composed of a plurality of columnar protrusions, the top surfaces of the columnar protrusions are arc-shaped, a plurality of grooves are formed in the surfaces of the columnar protrusions, hemostatic powder is filled in the grooves, the inner walls of the grooves are arc-shaped, a convex block is arranged at the bottom of each groove, the cross section of each groove is circular, the depth ratio of the diameter of each groove to the depth of each groove is 2:1, the height of each convex block is half of the depth of each groove, the hemostatic powder is microporous polysaccharide particles, and the height of each columnar protrusion is 0.12 mm.
The polymer coating layer comprises a plane textile material layer and a thermoplastic elastomer cellulose layer located on the plane textile material layer, a silver ion bactericide is sprayed on the thermoplastic elastomer cellulose layer, a plurality of columnar protrusions are arranged on the thermoplastic elastomer cellulose layer, the plane textile material layer is connected with the thermoplastic elastomer cellulose layer through a hot melting method, and the thermoplastic elastomer cellulose layer and the columnar protrusions are of an integral structure. The thermoplastic elastomer cellulose layer covers 33% of the area of the plane textile material layer and is positioned at the center of the plane textile material layer, and the plane textile material layer is made of antibacterial fiber containing silver ions.
The preparation method of the hemostatic and bactericidal medical dressing comprises the following steps:
(1) selecting antibacterial fiber containing silver ions to prepare a plane textile material layer;
(2) preparing a thermoplastic elastomer cellulosic layer;
(3) connecting the plane textile material layer and the thermoplastic elastomer cellulose layer by a hot melting method;
(4) hemostatic powder is filled in the grooves of the columnar bulges of the thermoplastic elastomer cellulose layer.
Example 3
A hemostatic and bactericidal medical dressing comprises a polymer coating layer, wherein a liquid absorbing area is arranged on the inner surface layer of the polymer coating layer and is composed of a plurality of columnar protrusions, the top surfaces of the columnar protrusions are arc-shaped, a plurality of grooves are formed in the surfaces of the columnar protrusions, hemostatic powder is filled in the grooves, the inner walls of the grooves are arc-shaped, a convex block is arranged at the bottom of each groove, the cross section of each groove is circular, the depth ratio of the diameter of each groove to the depth of each groove is 3:1, the height of each convex block is half of the depth of each groove, the hemostatic powder is microporous polysaccharide particles, and the height of each columnar protrusion is 0.15 mm.
The polymer coating layer comprises a plane textile material layer and a thermoplastic elastomer cellulose layer located on the plane textile material layer, a silver ion bactericide is sprayed on the thermoplastic elastomer cellulose layer, a plurality of columnar protrusions are arranged on the thermoplastic elastomer cellulose layer, the plane textile material layer is connected with the thermoplastic elastomer cellulose layer through a hot melting method, and the thermoplastic elastomer cellulose layer and the columnar protrusions are of an integral structure. The thermoplastic elastomer cellulose layer covers 35% of the area of the plane textile material layer and is positioned at the center of the plane textile material layer, and the plane textile material layer is made of antibacterial fiber containing silver ions.
The preparation method of the hemostatic and bactericidal medical dressing comprises the following steps:
(1) selecting antibacterial fiber containing silver ions to prepare a plane textile material layer;
(2) preparing a thermoplastic elastomer cellulosic layer;
(3) connecting the plane textile material layer and the thermoplastic elastomer cellulose layer by a hot melting method;
(4) hemostatic powder is filled in the grooves of the columnar bulges of the thermoplastic elastomer cellulose layer.
Example 4
A hemostatic and bactericidal medical dressing comprises a polymer coating layer, wherein a liquid absorbing area is arranged on the inner surface layer of the polymer coating layer and is composed of a plurality of columnar protrusions, the top surfaces of the columnar protrusions are arc-shaped, a plurality of grooves are formed in the surfaces of the columnar protrusions, hemostatic powder is filled in the grooves, the inner walls of the grooves are arc-shaped, a convex block is arranged at the bottom of each groove, the cross section of each groove is circular, the depth ratio of the diameter of each groove to the depth of each groove is 2:1, the height of each convex block is half of the depth of each groove, the hemostatic powder is microporous polysaccharide particles, and the height of each columnar protrusion is 0.8 mm.
The polymer coating layer comprises a plane textile material layer and a thermoplastic elastomer cellulose layer located on the plane textile material layer, a silver ion bactericide is sprayed on the thermoplastic elastomer cellulose layer, a plurality of columnar protrusions are arranged on the thermoplastic elastomer cellulose layer, the plane textile material layer is connected with the thermoplastic elastomer cellulose layer through a hot melting method, and the thermoplastic elastomer cellulose layer and the columnar protrusions are of an integral structure. The thermoplastic elastomer cellulose layer covers 38% of the area of the plane textile material layer and is positioned at the center of the plane textile material layer, and the plane textile material layer is made of antibacterial fiber containing silver ions.
The preparation method of the hemostatic and bactericidal medical dressing comprises the following steps:
(1) selecting antibacterial fiber containing silver ions to prepare a plane textile material layer;
(2) preparing a thermoplastic elastomer cellulosic layer;
(3) connecting the plane textile material layer and the thermoplastic elastomer cellulose layer by a hot melting method;
(4) hemostatic powder is filled in the grooves of the columnar bulges of the thermoplastic elastomer cellulose layer.
Example 5
A hemostatic and bactericidal medical dressing comprises a polymer coating layer, wherein a liquid absorbing area is arranged on the inner surface layer of the polymer coating layer and is composed of a plurality of columnar protrusions, the top surfaces of the columnar protrusions are arc-shaped, a plurality of grooves are formed in the surfaces of the columnar protrusions, hemostatic powder is filled in the grooves, the inner walls of the grooves are arc-shaped, a convex block is arranged at the bottom of each groove, the cross section of each groove is circular, the depth ratio of the diameter of each groove to the depth of each groove is 2:1, the height of each convex block is half of the depth of each groove, the hemostatic powder is microporous polysaccharide particles, and the height of each columnar protrusion is 0.2 mm.
The polymer coating layer comprises a plane textile material layer and a thermoplastic elastomer cellulose layer located on the plane textile material layer, a silver ion bactericide is sprayed on the thermoplastic elastomer cellulose layer, a plurality of columnar protrusions are arranged on the thermoplastic elastomer cellulose layer, the plane textile material layer is connected with the thermoplastic elastomer cellulose layer through a hot melting method, and the thermoplastic elastomer cellulose layer and the columnar protrusions are of an integral structure. The thermoplastic elastomer cellulose layer covers 40% of the area of the plane textile material layer and is positioned at the center of the plane textile material layer, and the plane textile material layer is made of antibacterial fiber containing silver ions.
The preparation method of the hemostatic and bactericidal medical dressing comprises the following steps:
(1) selecting antibacterial fiber containing silver ions to prepare a plane textile material layer;
(2) preparing a thermoplastic elastomer cellulosic layer;
(3) connecting the plane textile material layer and the thermoplastic elastomer cellulose layer by a hot melting method;
(4) hemostatic powder is filled in the grooves of the columnar bulges of the thermoplastic elastomer cellulose layer.
The hemostatic and bactericidal medical dressings prepared in examples 1 to 5 were cut into 5 × 5cm square pieces, and dipped with a cotton swab at a concentration of 1 × 104CFU/m colony solution is cultured on a peptone culture medium, the selected strains are staphylococcus aureus, pseudomonas aeruginosa, candida albicans and wound aspergillus, then the square sheets are applied on the colonies, each experiment is repeated for 3 times, the growth of aseptic colonies is observed after 7 days, and the statistical result is shown in table 1.
The hemostatic and bactericidal medical dressings in examples 1-5 have no problem of secondary mechanical damage in the replacement process after being used.
The use of 12 bedsore patients was monitored, the bedsore wound size was 5.35 + -1.08 cm long and 4.12 + -1.58 cm wide with 0.98 + -0.09 cm deep, the pain during the first dressing change was followed, the number of severe pain was 0 during the first change, the number of pain was 2 all the time, the number of mild pain was 4, and the number of no pain was 6. And the dressing removal rate on the bedsore is as high as 97.3%. Only 1 of 12 people showed signs of infection during use.
In light of the foregoing description of the preferred embodiment of the present invention, many modifications and variations will be apparent to those skilled in the art without departing from the spirit and scope of the invention. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention. The technical scope of the present invention is not limited to the content of the specification, and must be determined according to the scope of the claims.
Claims (9)
1. The hemostatic and bactericidal medical dressing is characterized in that: including the polymer coating, be provided with the imbibition district on the inner surface layer of polymer coating, the imbibition district comprises a plurality of column archs, the bellied top surface of column is the arc, the bellied surface of column has a plurality of recesses, the recess intussuseption is filled with hemostatic powder.
2. The hemostatic and bactericidal medical dressing as claimed in claim 1, wherein: the polymer coating layer comprises a plane textile material layer and a thermoplastic elastomer cellulose layer located on the plane textile material layer, a silver ion bactericide is sprayed on the thermoplastic elastomer cellulose layer, a plurality of columnar protrusions are arranged on the thermoplastic elastomer cellulose layer, the plane textile material layer and the thermoplastic elastomer cellulose layer are connected through a hot melting method, and the thermoplastic elastomer cellulose layer and the columnar protrusions are of an integral structure.
3. The hemostatic and bactericidal medical dressing as claimed in claim 2, wherein: the thermoplastic elastomer cellulose layer covers 30-40% of the area of the plane textile material layer and is positioned in the center of the plane textile material layer.
4. The hemostatic and bactericidal medical dressing as claimed in claim 1, wherein: the plane textile material layer is made of antibacterial fiber containing silver ions.
5. The hemostatic and bactericidal medical dressing as claimed in claim 1, wherein: the inner wall of the groove is arc-shaped, a convex block is arranged at the bottom of the groove, and the cross section of the groove is circular.
6. The hemostatic and bactericidal medical dressing as claimed in claim 1, wherein: the diameter of the groove is (3:1) - (2:1) in depth ratio, and the height of the bump is half of the depth of the groove.
7. The hemostatic and bactericidal medical dressing as claimed in claim 1, wherein: the hemostatic powder is microporous polysaccharide particles.
8. The hemostatic and bactericidal medical dressing as claimed in claim 1, wherein: the height of the columnar bulge is 0.1-0.2 mm.
9. A preparation method of a medical dressing for hemostasis and sterilization is characterized by comprising the following steps: the preparation method comprises the following steps:
(1) selecting antibacterial fiber containing silver ions to prepare a plane textile material layer;
(2) preparing a thermoplastic elastomer cellulosic layer;
(3) connecting the plane textile material layer and the thermoplastic elastomer cellulose layer by a hot melting method;
(4) hemostatic powder is filled in the grooves of the columnar bulges of the thermoplastic elastomer cellulose layer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010579996.1A CN111685937A (en) | 2020-06-23 | 2020-06-23 | Hemostatic and bactericidal medical dressing and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010579996.1A CN111685937A (en) | 2020-06-23 | 2020-06-23 | Hemostatic and bactericidal medical dressing and preparation method thereof |
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| Publication Number | Publication Date |
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| CN111685937A true CN111685937A (en) | 2020-09-22 |
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| CN202010579996.1A Pending CN111685937A (en) | 2020-06-23 | 2020-06-23 | Hemostatic and bactericidal medical dressing and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113350045A (en) * | 2021-06-29 | 2021-09-07 | 三特瑞(南通)医用材料有限公司 | Medical developing dressing and preparation method and production equipment thereof |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109045339A (en) * | 2018-08-29 | 2018-12-21 | 郑州工程技术学院 | A kind of medical compound antiseptic dressing and preparation method thereof |
| CN208808835U (en) * | 2017-09-30 | 2019-05-03 | 谢光娟 | A kind of medical dressing |
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| US20030045825A1 (en) * | 2001-06-12 | 2003-03-06 | Etheredge Robert W. | Wound dressing and method of making |
| CN208808835U (en) * | 2017-09-30 | 2019-05-03 | 谢光娟 | A kind of medical dressing |
| CN109045339A (en) * | 2018-08-29 | 2018-12-21 | 郑州工程技术学院 | A kind of medical compound antiseptic dressing and preparation method thereof |
| CN209154217U (en) * | 2018-10-25 | 2019-07-26 | 南京林业大学 | A kind of new medical hydrogel combine dressing |
| CN209966769U (en) * | 2019-04-03 | 2020-01-21 | 常州华联保健敷料有限公司 | Antibacterial adhesive bandage with silver ions |
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| CN113350045A (en) * | 2021-06-29 | 2021-09-07 | 三特瑞(南通)医用材料有限公司 | Medical developing dressing and preparation method and production equipment thereof |
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