CN113350045A - Medical developing dressing and preparation method and production equipment thereof - Google Patents
Medical developing dressing and preparation method and production equipment thereof Download PDFInfo
- Publication number
- CN113350045A CN113350045A CN202110725678.6A CN202110725678A CN113350045A CN 113350045 A CN113350045 A CN 113350045A CN 202110725678 A CN202110725678 A CN 202110725678A CN 113350045 A CN113350045 A CN 113350045A
- Authority
- CN
- China
- Prior art keywords
- developing
- gauze
- frame
- woven gauze
- medical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 23
- 238000002360 preparation method Methods 0.000 title claims abstract description 18
- 239000007788 liquid Substances 0.000 claims abstract description 108
- 239000010410 layer Substances 0.000 claims abstract description 97
- 230000000844 anti-bacterial effect Effects 0.000 claims abstract description 78
- 230000002745 absorbent Effects 0.000 claims abstract description 51
- 239000002250 absorbent Substances 0.000 claims abstract description 51
- 238000010521 absorption reaction Methods 0.000 claims abstract description 27
- 230000002439 hemostatic effect Effects 0.000 claims abstract description 27
- 239000002131 composite material Substances 0.000 claims abstract description 23
- 239000002344 surface layer Substances 0.000 claims abstract description 11
- 239000003814 drug Substances 0.000 claims description 62
- 239000000463 material Substances 0.000 claims description 54
- 238000004080 punching Methods 0.000 claims description 47
- 239000000243 solution Substances 0.000 claims description 47
- 229920001187 thermosetting polymer Polymers 0.000 claims description 30
- 238000001035 drying Methods 0.000 claims description 27
- 230000007246 mechanism Effects 0.000 claims description 26
- 238000011161 development Methods 0.000 claims description 23
- 238000000034 method Methods 0.000 claims description 21
- 230000006835 compression Effects 0.000 claims description 20
- 238000007906 compression Methods 0.000 claims description 20
- 238000011049 filling Methods 0.000 claims description 20
- 238000010438 heat treatment Methods 0.000 claims description 17
- 229940030225 antihemorrhagics Drugs 0.000 claims description 16
- 239000011248 coating agent Substances 0.000 claims description 16
- 238000000576 coating method Methods 0.000 claims description 16
- 239000002874 hemostatic agent Substances 0.000 claims description 16
- 238000003860 storage Methods 0.000 claims description 15
- 238000009434 installation Methods 0.000 claims description 11
- 230000001954 sterilising effect Effects 0.000 claims description 11
- 238000001125 extrusion Methods 0.000 claims description 10
- 238000007789 sealing Methods 0.000 claims description 10
- 229910052709 silver Inorganic materials 0.000 claims description 10
- 239000004332 silver Substances 0.000 claims description 10
- -1 silver ions Chemical class 0.000 claims description 10
- 238000005520 cutting process Methods 0.000 claims description 9
- 230000003115 biocidal effect Effects 0.000 claims description 8
- 238000002156 mixing Methods 0.000 claims description 8
- 238000004806 packaging method and process Methods 0.000 claims description 8
- 239000011347 resin Substances 0.000 claims description 8
- 229920005989 resin Polymers 0.000 claims description 8
- 235000010410 calcium alginate Nutrition 0.000 claims description 7
- 239000000648 calcium alginate Substances 0.000 claims description 7
- 229960002681 calcium alginate Drugs 0.000 claims description 7
- OKHHGHGGPDJQHR-YMOPUZKJSA-L calcium;(2s,3s,4s,5s,6r)-6-[(2r,3s,4r,5s,6r)-2-carboxy-6-[(2r,3s,4r,5s,6r)-2-carboxylato-4,5,6-trihydroxyoxan-3-yl]oxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylate Chemical compound [Ca+2].O[C@@H]1[C@H](O)[C@H](O)O[C@@H](C([O-])=O)[C@H]1O[C@H]1[C@@H](O)[C@@H](O)[C@H](O[C@H]2[C@H]([C@@H](O)[C@H](O)[C@H](O2)C([O-])=O)O)[C@H](C(O)=O)O1 OKHHGHGGPDJQHR-YMOPUZKJSA-L 0.000 claims description 7
- 238000005238 degreasing Methods 0.000 claims description 7
- 238000001723 curing Methods 0.000 claims description 6
- 239000011259 mixed solution Substances 0.000 claims description 6
- 230000001105 regulatory effect Effects 0.000 claims description 6
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims description 5
- 238000013329 compounding Methods 0.000 claims description 5
- 235000010413 sodium alginate Nutrition 0.000 claims description 5
- 239000000661 sodium alginate Substances 0.000 claims description 5
- 229940005550 sodium alginate Drugs 0.000 claims description 5
- 238000004659 sterilization and disinfection Methods 0.000 claims description 5
- 239000000843 powder Substances 0.000 claims description 4
- 239000008280 blood Substances 0.000 claims description 3
- 210000004369 blood Anatomy 0.000 claims description 3
- 238000002059 diagnostic imaging Methods 0.000 claims description 3
- 238000013007 heat curing Methods 0.000 claims description 3
- 239000004745 nonwoven fabric Substances 0.000 claims description 3
- 239000002245 particle Substances 0.000 claims description 3
- 238000007664 blowing Methods 0.000 claims description 2
- 238000005253 cladding Methods 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 14
- 230000023597 hemostasis Effects 0.000 abstract description 4
- 210000003128 head Anatomy 0.000 description 27
- 229940079593 drug Drugs 0.000 description 13
- 238000003825 pressing Methods 0.000 description 8
- 238000005213 imbibition Methods 0.000 description 7
- 238000007711 solidification Methods 0.000 description 7
- 230000008023 solidification Effects 0.000 description 7
- 238000010924 continuous production Methods 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- 238000004804 winding Methods 0.000 description 5
- 230000000845 anti-microbial effect Effects 0.000 description 4
- 230000009471 action Effects 0.000 description 3
- 230000003139 buffering effect Effects 0.000 description 3
- 238000010276 construction Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- FOIXSVOLVBLSDH-UHFFFAOYSA-N Silver ion Chemical compound [Ag+] FOIXSVOLVBLSDH-UHFFFAOYSA-N 0.000 description 2
- 210000000683 abdominal cavity Anatomy 0.000 description 2
- 230000002155 anti-virotic effect Effects 0.000 description 2
- 239000004599 antimicrobial Substances 0.000 description 2
- 239000011449 brick Substances 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 238000007599 discharging Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000000465 moulding Methods 0.000 description 2
- 230000002035 prolonged effect Effects 0.000 description 2
- 238000005096 rolling process Methods 0.000 description 2
- 238000002791 soaking Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 238000009941 weaving Methods 0.000 description 2
- 230000003187 abdominal effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 210000000416 exudates and transudate Anatomy 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 210000000887 face Anatomy 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 229920001002 functional polymer Polymers 0.000 description 1
- 239000003349 gelling agent Substances 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000017525 heat dissipation Effects 0.000 description 1
- 238000009998 heat setting Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 239000000700 radioactive tracer Substances 0.000 description 1
- 230000002787 reinforcement Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 238000001029 thermal curing Methods 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/15—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
- A61F13/44—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators with radio-opaque material or signalling means for residual material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/00051—Accessories for dressings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/00051—Accessories for dressings
- A61F13/00059—Accessories for dressings provided with visual effects, e.g. printed or colored
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/00051—Accessories for dressings
- A61F13/00063—Accessories for dressings comprising medicaments or additives, e.g. odor control, PH control, debriding, antimicrobic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/00987—Apparatus or processes for manufacturing non-adhesive dressings or bandages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/01—Non-adhesive bandages or dressings
- A61F13/01008—Non-adhesive bandages or dressings characterised by the material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/01—Non-adhesive bandages or dressings
- A61F13/01021—Non-adhesive bandages or dressings characterised by the structure of the dressing
- A61F13/01029—Non-adhesive bandages or dressings characterised by the structure of the dressing made of multiple layers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/01—Non-adhesive bandages or dressings
- A61F13/01034—Non-adhesive bandages or dressings characterised by a property
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
- A61F13/0203—Adhesive bandages or dressings with fluid retention members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
- A61F13/0276—Apparatus or processes for manufacturing adhesive dressings or bandages
- A61F13/0286—Apparatus or processes for manufacturing adhesive dressings or bandages manufacturing of non adhesive dressings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/15—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
- A61F13/36—Surgical swabs, e.g. for absorbency or packing body cavities during surgery
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Manufacturing & Machinery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Surgery (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Materials For Medical Uses (AREA)
Abstract
The invention provides a medical developing dressing and a preparation method and production equipment thereof, relating to the technical field of preparation of medical gel dressings, wherein the medical developing dressing comprises composite non-woven gauze and absorbent gauze, one side of the non-woven gauze, which is far away from the absorbent gauze, is provided with at least two developing lines which are parallel to each other and are uniformly arranged, the outer surface layer of the non-woven gauze is provided with an antibacterial layer and a liquid absorption layer which coat the non-woven gauze, the antibacterial layer is positioned between the non-woven gauze and the liquid absorption layer, and the developing lines are positioned between the antibacterial layer and the non-woven gauze; the non-woven gauze is evenly provided with a plurality of containing grooves which are positioned between adjacent developing lines, the opening of each containing groove is positioned on one side of the non-woven gauze, which is close to the absorbent gauze, and is protruded towards one side far away from the absorbent gauze, and the containing grooves are filled with hemostatic. The developing dressing prepared by the invention has stronger liquid absorption capacity and hemostasis capacity, effectively improves the using effect, can be tracked by medical images, is not easy to fall off, and avoids medical accidents caused by leaving the medical developing dressing in the body of a patient.
Description
Technical Field
The invention relates to the technical field of preparation of medical gel dressing, in particular to a medical developing dressing and a preparation method and production equipment thereof.
Background
Medical dressings such as gauze pieces, abdominal pads and the like are widely applied to medical operations, particularly abdominal cavity operations, the amount of the gauze pieces is large, once blood is soaked, the gauze pieces or abdominal cavity tissues are difficult to distinguish by naked eyes, and serious medical accidents can be caused if the gauze is carelessly left in a patient body.
Disclosure of Invention
The invention aims to provide a medical developing dressing, a preparation method and production equipment thereof, the medical developing dressing produced and prepared by the production method has stronger liquid absorption capacity and hemostasis capacity, the use effect in the operation is effectively improved, the medical developing dressing can be tracked by medical images, a developing line is not easy to fall off, and medical accidents caused by the fact that the medical developing dressing is left in a patient body are avoided.
The technical purpose of the invention is realized by the following technical scheme:
a medical developing dressing comprises a non-woven gauze and a absorbent gauze which are compounded, wherein at least two developing lines which are parallel to each other and are uniformly arranged are arranged on one side of the non-woven gauze, which is far away from the absorbent gauze, an antibacterial layer and a liquid absorption layer which coat the non-woven gauze are arranged on the outer surface layer of the non-woven gauze, the antibacterial layer is positioned between the non-woven gauze and the liquid absorption layer, and the developing lines are positioned between the antibacterial layer and the non-woven gauze; evenly be equipped with a plurality of storage tanks that are located between the adjacent developing line on the non-woven gauze, the opening of storage tank is located one side that the non-woven gauze is close to the absorbent gauze, and its one side arch to keeping away from the absorbent gauze, the storage tank intussuseption is filled with hemostatic.
By adopting the technical scheme, the absorbent gauze is contacted with the wound when in use, the absorption force of the absorbent gauze can be fully utilized, and the pain of a patient is relieved. Set up to two at least developing lines that are parallel to each other and evenly set up on the non-woven gauze, the medical image of being convenient for is tracked, and guarantees the tracer effect, avoids medical developing dressing to leave over and causes the medical accident in patient's body. The developing line is located between the antibacterial layer and the non-woven gauze, the antibacterial layer and the liquid absorption layer are equivalently used for carrying out secondary reinforcement on the developing line, pressure can be applied to the developing line when the liquid absorption layer absorbs liquid and expands, and the developing line is guaranteed to be not prone to falling off from the non-woven gauze. Set up antibiotic layer and imbibition layer, guarantee the bacterinertness and the imbibition ability of medical development dressing, and set up the storage tank and pack the hemostatic in the storage tank, utilize the hemostatic to stanch to the wound, effectively improve the imbibition ability and the hemostasis ability of medical development dressing, improve the result of use of medical development dressing in the operation.
Furthermore, the development line is fixed on the surface of the non-woven gauze by adopting a method of dripping molten developing solution, extruding by a compression roller and thermally curing.
By adopting the technical scheme, the developing lines are fixed on the surface of the non-woven gauze by using the method of dripping the molten developing solution, extruding by the compression roller and thermally curing, compared with the method of weaving the developing lines in the non-woven gauze, the production requirement on the non-woven gauze can be reduced, compared with the method of scalding the developing lines, the developing lines are firstly molten, then physically extruded by the compression roller and finally thermally cured and shaped, and the developing lines are fixed on the non-woven gauze more firmly and are not easy to fall off.
A preparation method of a medical developing dressing comprises the following specific steps:
s1, fixing a developing line; fixing the developing line on the non-woven gauze by using a developing line dripping device, dripping the molten developing solution onto the non-woven gauze, extruding the developing solution into a linear structure by using a compression roller, and solidifying the linear developing solution into the developing line fixed on the non-woven gauze by adopting thermal curing;
s2, covering an antibacterial layer; immersing the non-woven gauze subjected to the step S1 into an antibacterial solution, and forming an antibacterial layer on the surface layer of the non-woven gauze after the antibacterial solution is solidified;
s3, covering a liquid absorption layer; immersing the nonwoven gauze processed in the step S2 in the mixed solution, and forming a liquid absorption layer on the surface layer of the antibacterial layer after the mixed solution is solidified;
s4, punching an accommodating groove; uniformly punching a plurality of accommodating grooves on one side of the non-woven gauze which is far away from the developing lines in the step S3 by using a punching mechanism, wherein the plurality of accommodating grooves are uniformly distributed between two adjacent developing lines;
s5, adding a hemostatic agent; adding a hemostatic agent into the accommodating groove formed in the step S4 by stamping, wherein the hemostatic agent is one of blood particles, hemostatic powder or hemostatic gel;
s6, compounding absorbent gauze; covering absorbent gauze on the surface of the non-woven gauze subjected to the step S5, covering the opening of the accommodating groove with the absorbent gauze, and compounding and fixing the absorbent gauze and the non-woven gauze to form the composite dressing;
s7, slitting and packaging; cutting the composite dressing prepared in the step S6 into a required shape and packaging to complete the preparation of the medical dressing;
s8, sterilizing and warehousing; and (5) sterilizing the medical dressing prepared in the step S7, and storing in a warehouse after sterilization.
By adopting the technical scheme, the developing line is fixed on the surface of the non-woven gauze by adopting a method of dripping molten developing solution, extruding by a compression roller and thermally curing, and the developing line is firmly fixed and is not easy to fall off; the antibacterial layer and the liquid absorption layer are formed in a manner of infiltrating the antibacterial liquid and the mixed liquid after solidification, no additional operation is needed, convenience and trouble are achieved, and the antibacterial layer and the liquid absorption layer are not easy to fall off; the containing groove is directly punched by the punching mechanism without cutting the non-woven gauze, the hemostatic is added into the containing groove and compositely sealed by the absorbent gauze, and the hemostatic is prevented from falling off from the non-woven gauze; and finally, cutting the composite dressing into a required shape, packaging, and finally sterilizing and warehousing. Accomplish the preparation to medical development dressing through above-mentioned eight steps, the fixed mode of development line is different, antibiotic layer and imbibition layer's preparation is simple, the storage tank adopts the punching press rather than cutting out the mode, above-mentioned process flow is simple, and the medical development dressing of preparation has stronger imbibition ability and hemostasis ability, effectively improves the result of use in the operation, can be tracked by medical image, avoids medical development dressing to leave over and causes the medical accident in patient's is internal, and the development line is difficult for droing.
Further, in the step S2, the antibacterial liquid is a calcium alginate solution containing silver ions, and the concentration of the silver ions is 55% to 70%.
By adopting the technical scheme, the calcium alginate solution containing silver ions is used as the antibacterial liquid, the silver ions have strong sterilization and disinfection effects, the calcium alginate can be used as a thickening agent, a stabilizing agent and a gelling agent, and the calcium alginate containing the silver ions is easy to adhere to the non-woven gauze to form an antibacterial layer, so that the antibacterial nonwoven gauze has strong antibacterial property and firmness. The silver ion concentration is 55% -70%, so that the antibacterial layer formed by adhering calcium alginate on the non-woven gauze has high silver ion content, and the antibacterial and antivirus effects of the antibacterial layer are guaranteed.
Further, in step S3, the mixed solution is prepared by mixing super absorbent resin and sodium alginate at a ratio of 2: 1.
By adopting the technical scheme, the super absorbent resin is a novel functional polymer material, one half of the super absorbent resin can absorb water which is more than 100 times of the volume of the resin, the sodium alginate has stability, viscosity and safety, after the non-woven gauze is soaked by the mixed liquid which is formed by mixing the super absorbent resin and the sodium alginate according to the proportion of 2:1, the super absorbent resin is easily adhered to the surface of the non-woven gauze, a liquid absorption layer can be formed after solidification, and the formed liquid absorption layer has ultrahigh water absorption capacity.
A production device of medical developing dressing comprises a developing line dripping device used in step S1, a coating device used in steps S2 and S3 and a medicine filling device used in steps S4-S6, wherein the developing line dripping device, the coating device and the medicine filling device respectively comprise a material placing frame used for unreeling non-woven gauze and a material collecting frame used for reeling non-woven gauze.
By adopting the technical scheme, the developing line dripping device is utilized to realize that the developing line is fixed on the surface of the non-woven gauze by adopting the method of dripping molten developing solution, extruding by a compression roller and thermally curing; the coating device is a continuous production line, and the antibacterial layer and the liquid absorbing layer are successively and continuously coated without separation, so that the working procedure is simplified; the medicine filling device is also a continuous production line, and the steps S4-S6 of punching the containing groove, adding the hemostatic agent and the composite absorbent gauze are successively completed, so that the operation is completed in one step, the equipment process is simplified, the production efficiency is accelerated, and the productivity is improved. The developing line dripping device, the coating device and the medicine filling device comprise a material placing frame and a material receiving frame, the material placing frame is used for releasing the non-woven gauze to be processed, the material receiving frame is used for rolling the processed non-woven gauze or composite dressing, and the structures of the developing line dripping device, the coating device and the medicine filling device are the same.
Furthermore, the developing line dripping and fixing device comprises a material placing frame, a material guide frame, a dripping frame, an extrusion frame, a thermosetting box, a buffer frame and a material receiving frame which are sequentially arranged along the feeding direction;
the guide frame and the buffer frame are respectively provided with a plurality of guide rollers which are horizontally arranged perpendicular to the feeding direction, and the guide rollers are arranged in a vertically staggered manner;
the drip stand is provided with a heating tank for containing developing solution, the drip stand is also provided with an installation rod arranged along the length direction of the guide roller and a support plate positioned below the installation rod, the installation rod is provided with at least two drip heads uniformly arranged along the length direction of the installation rod, and the drip heads are communicated with the heating tank and provided with speed regulating valves;
two compression rollers which are arranged symmetrically up and down and are parallel to the guide roller are positioned and rotatably arranged on the extrusion frame, and the upper end surface of the supporting plate is positioned on the symmetrical plane of the two compression rollers;
a plurality of stroke-increasing rollers parallel to the guide rollers are arranged in the thermosetting box along the length direction of the thermosetting box, and three layers are arranged above and below the stroke-increasing rollers; the hot-fixing box is uniformly provided with a plurality of air heaters, and the middle temperature in the hot-fixing box is higher than the temperatures of the two ends.
By adopting the technical scheme, the non-woven gauze roll to be processed is placed on the material placing frame to be released, the S-shaped part bypasses a plurality of guide rollers on the material guiding frame to be conveyed forwards, and when the non-woven gauze roll is conveyed to the dropping frame, the dropping head drops the developing solution melted in the heating tank onto the non-woven gauze. The supporting plate ensures that the non-woven gauze flatly enters between two compression rollers on the extrusion frame, so that the flowing of the developing solution is avoided, and the heating tank ensures that the developing solution is always in a molten state, so that the dripping is convenient; the speed regulating valve on the liquid dropping head can regulate the speed of the liquid dropping head dropping the developing solution. Continuously conveying the non-woven gauze to an extrusion frame after dripping the developing solution on the non-woven gauze, penetrating the non-woven gauze from the space between two compression rollers, and flattening the developing solution into linear developing solution to be coated on the surface of the non-woven gauze through the extrusion of the two compression rollers; and then the yarn enters a thermosetting box, the S-shaped yarn bypasses the three layers of stroke-increasing rollers, and the stroke-increasing rollers are positioned below the non-spun yarn cloth. After thermosetting molding in the thermosetting box, the developing solution is fixed on the surface of the non-woven gauze. The three layers of the range extending rollers can improve the travel of the non-woven gauze in the thermosetting box under the condition that the length of the thermosetting box is fixed, improve the thermosetting time of the developing lines on the non-woven gauze and ensure the fixing effect of the developing lines on the non-woven gauze. The hot air blower is used for heating, the temperature in the middle of the hot curing box is higher than the temperature at two ends, so that the relaxation time is provided for heating the developing solution, and the forming effect of the developing line is ensured. After the non-woven gauze is sent out from the thermosetting box, the S-shaped part bypasses the guide roller on the buffer frame to dissipate heat, and then is rolled by the material receiving frame, so that the phenomenon that the heat brought out from the thermosetting box by direct rolling is covered to influence the quality of the non-woven gauze is avoided.
Further, the cladding device includes blowing frame, antibiotic liquid case, stoving case, mixing liquid case, drying cabinet and the receipts work or material rest that sets gradually along the direction of feed, all be equipped with the material roller that winds that a plurality of perpendicular to direction of feed levels set up along its length direction in antibiotic liquid case, stoving case, mixing liquid case and the drying cabinet, just it is provided with the multilayer to crisscross from top to bottom around the material roller.
By adopting the technical scheme, the non-woven gauze roll with the developing lines is arranged on the material placing frame to be released, the non-woven gauze with the developing lines sequentially enters the antibacterial liquid box, the drying box, the mixed liquid box and the drying box, and is soaked in the antibacterial liquid box, so that the antibacterial liquid soaks the non-woven gauze, and then the non-woven gauze is dried in the drying box, the solidification of the antibacterial liquid is accelerated, and the surface layer of the non-woven gauze and the developing lines are coated by the formed antibacterial layer; the non-woven gauze coated with the antibacterial layer enters the mixed liquid box to be soaked in the mixed liquid, the mixed liquid soaks the non-woven gauze, then the non-woven gauze enters the drying box to be dried, solidification of the mixed liquid is accelerated, a liquid absorption layer formed by the non-woven gauze is coated on the outer surface of the antibacterial layer, and finally the non-woven gauze is rolled by the material collecting rack. Wherein, all be equipped with the multilayer in antibiotic liquid case, stoving case, mixed liquid case and the drying cabinet and wind the material roller, can increase the stroke of non-woven gauze like this, increase its soaking and dry time of drying, guarantee the formation effect of antibiotic layer and imbibition layer.
Furthermore, the medicine filling device comprises a material placing frame, a punching mechanism, a medicine adding mechanism, a degreasing gauze frame, a composite frame and a material receiving frame which are arranged in sequence;
the stamping mechanism comprises a stamping table and a stamping frame positioned above the stamping table, a template is arranged on the upper end face of the stamping table, and a stamping head corresponding to the template is arranged on the stamping frame;
the drug adding mechanism comprises a drug adding frame, a drug tank for containing a hemostatic agent is arranged on the drug adding frame, a drug adding seat is arranged on the drug adding frame, a plurality of drug adding nozzles communicated with the drug tank are arranged on the lower end face of the drug adding seat, and the drug adding nozzles are in one-to-one correspondence with the punching heads along the length direction of the drug adding frame;
at least two groups of roller sets are arranged on the composite frame along the feeding direction, each group of roller sets comprises two heat-seal rollers which are vertically symmetrical and horizontally arranged along the feeding direction, and notches matched with the accommodating grooves are arranged on the heat-seal rollers below the heat-seal rollers.
By adopting the technical scheme, the non-woven gauze roll which is provided with the developing lines and is covered with the antibacterial layer and the liquid absorbing layer is arranged on the material placing frame to be released and sent to the punching mechanism to pass through the upper part of the template on the punching table, and one side of the non-woven gauze which is provided with the developing lines is positioned below; the punching head on the punching frame punches downwards, and the containing groove is punched on the non-woven gauze under the matching action of the punching head and the template. Then the non-woven gauze continues to move forward to the medicine adding mechanism, and the hemostatic in the medicine tank is added into the containing groove by the medicine adding nozzles. In the process that the non-woven gauze is conveyed forwards continuously, the non-woven gauze frame is provided with the non-woven gauze roll for releasing, the non-woven gauze frame covers the non-woven gauze to plug the opening of the containing groove, the non-woven gauze roll moves to the position of the composite frame along with the non-woven gauze, the non-woven gauze roll penetrates through the heat sealing rollers in the roller set, the non-woven gauze and the non-woven gauze are fixed through the heat sealing action of the heat sealing rollers, the composite dressing is formed, and the non-woven gauze roll are rolled by the material collecting frame. Wherein, the roller set is equipped with at least two sets ofly, guarantees the fixed effect of heat seal to non-woven fabrics and absorbent gauze, avoids the storage tank to flatten with storage tank complex breach.
Furthermore, the rectangular array on the template is provided with a plurality of pits, the stamping heads correspond to the pits on the template one by one, and the stamping heads are electrified and heated.
Through adopting above-mentioned technical scheme, pit and the cooperation of punching press head one-to-one on the template realize punching out the storage tank on the non-woven gauze, and the storage tank heating is finalized the design to punching press head ohmic heating, avoids the non-woven gauze resilience of storage tank department, influences the mechanism that adds the hemostatic agent of adding in to the storage tank.
In conclusion, the invention has the following beneficial effects:
1. the developing lines are arranged on the non-woven gauze and are coated by the antibacterial layer and the liquid absorption layer, the non-woven gauze is provided with the containing groove, the hemostatic agent is added in the containing groove, the absorbent gauze is used for compounding with the non-woven gauze to seal the containing groove, the medical developing dressing has strong liquid absorption capacity and hemostatic capacity, the using effect in the operation is effectively improved, the medical developing dressing can be tracked by medical images, the developing lines are not easy to fall off, and medical accidents caused by the fact that the medical developing dressing is left in a patient body are avoided;
2. the developing lines are fixed on the surface of the non-woven gauze by adopting a method of dripping molten developing solution, extruding by a compression roller and thermosetting, compared with the method of weaving the developing lines in the non-woven gauze, the production requirement on the non-woven gauze can be reduced, compared with the method of scalding the developing lines, the developing lines are firstly molten, then physically extruded by the compression roller and finally thermosetting and shaped, and the developing lines are fixed on the non-woven gauze more firmly and are not easy to fall off;
3. the preparation method and the processing equipment of the invention are used for preparing the medical developing dressing, the fixing modes of the developing lines are different, the preparation of the antibacterial layer and the liquid absorbing layer is simple, the accommodating groove adopts a stamping mode rather than a cutting mode, the process flow is simple, the equipment is simplified, the production line continuously operates, the prepared medical developing dressing has stronger liquid absorbing capacity and hemostatic capacity, the use effect in the operation is effectively improved, the medical developing dressing can be tracked by medical images, the developing lines are not easy to fall off, and the medical developing dressing is prevented from being left in the body of a patient to cause medical accidents.
Drawings
FIG. 1 is a schematic view of the overall construction of a medical imaging dressing;
FIG. 2 is a flow chart of a method of making a medical imaging dressing;
FIG. 3 is a schematic view showing the overall structure of a development line drip-fixing device in a production apparatus for a medical development dressing;
fig. 4 is a partial structural sectional view of the developing wire dripping device;
FIG. 5 is a schematic view showing the overall construction of a coating means in the production apparatus for a medical developing dressing;
FIG. 6 is a schematic view showing the overall construction of a filling means in a production apparatus for a medical developing dressing;
fig. 7 is a schematic structural diagram of a punching mechanism and a dosing mechanism in the drug filling device.
In the figure, 1, non-woven gauze; 11. developing lines; 12. an antimicrobial layer; 13. a liquid absorption layer; 14. a containing groove; 15. a hemostatic agent; 16. absorbent gauze; 2. a material placing frame; 3. a material receiving frame; 4. a developing line dispensing device; 41. a material guide frame; 42. a drip stand; 421. a heating tank; 422. mounting a rod; 423. a support plate; 424. a liquid dropping head; 43. an extrusion frame; 431. a compression roller; 44. a thermosetting box; 441. a range extending roller; 442. a hot air blower; 45. a buffer frame; 46. a guide roller; 5. a coating device; 51. an antimicrobial fluid tank; 52. a drying box; 53. a mixed liquid tank; 54. a drying oven; 55. a winding roller; 6. a drug filling device; 61. a stamping mechanism; 611. a punching stage; 612. a punching frame; 613. a template; 6131. a pit; 614. punching a head; 62. a dosing mechanism; 621. a medicine adding frame; 622. a medicine tank; 623. a medicine adding seat; 624. a dosing nozzle; 63. a degreasing gauze frame; 64. a composite frame; 641. a roller set; 6411. and (4) a heat seal roller.
Detailed Description
The present invention will be described in further detail with reference to the following drawings and examples. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
Medical developing dressingAs shown in fig. 1, the absorbent gauze comprises an upper non-woven gauze 1 and a lower non-woven gauze 16 which are compounded, and the absorbent gauze 16 is in direct contact with a wound when in use. At least two developing lines 11 which are parallel to each other and are uniformly arranged are arranged on one side of the non-woven gauze 1 far away from the absorbent gauze 16, an antibacterial layer 12 which coats the non-woven gauze 1 is arranged on the outer surface layer of the non-woven gauze 1, meanwhile, the antibacterial layer 12 also coats the developing lines 11, and the antibacterial performance of the dressing is improved by utilizing the antibacterial layer 12. In the field of antibiosisThe layer 12 is provided with a liquid absorbent layer 13 covering the outer surface thereof, and the liquid absorbent layer 13 is used to clean the wound exudate. A plurality of containing grooves 14 are uniformly formed in the non-woven gauze 1 and located between the adjacent developing lines 11, the openings of the containing grooves 14 are located on one side, close to the absorbent gauze 16, of the non-woven gauze 1 and protrude towards one side far away from the absorbent gauze 16, and the containing grooves 14 are filled with hemostatic 15, namely the absorbent gauze 16 seals the openings of the containing grooves 14. Wherein the hemostatic agent 15 is one of hemostatic granule, hemostatic powder or hemostatic gel.
As shown in fig. 1, in the present embodiment, three developing lines 11 are uniformly arranged, one developing line 11 is located on the central line of the nonwoven scrim 1, the other two developing lines 11 are located on both sides, and the three developing lines 11 are fixed on the surface of the nonwoven scrim 1 by dropping the molten developing solution, pressing with a pressing roller, and heat-curing, so that compared with the case where the developing lines 11 are woven into the nonwoven scrim 1, the production requirement for the nonwoven scrim 1 can be reduced, and compared with the case where the developing lines 11 are hot-pressed, the developing lines 11 are first molten, then physically pressed with the pressing roller 431, and finally heat-cured, and the fixing of the developing lines 11 on the nonwoven scrim 1 is firmer and are not easy to fall off. Above-mentioned medical development dressing has stronger imbibition ability and hemostatic ability, effectively improves the result of use in the operation, can be tracked by medical image, and develops line 11 and be difficult for droing, avoids medical development dressing to leave over and causes the medical accident in patient's body.
Preparation method of medical developing dressingAs shown in fig. 1 and 2, the specific steps are as follows:
s1, dropping and fixing the developing line 11; fixing the developing line 11 on the non-woven gauze 1 by using the developing line dripping device 4, dripping the molten developing solution on the non-woven gauze 1, extruding the developing solution into a linear structure by using a compression roller, and solidifying the linear developing solution into the developing line 11 and fixing the developing line 11 on the non-woven gauze 1 by adopting thermosetting, so that the developing line 11 is more firmly fixed on the non-woven gauze 1 and is not easy to fall off.
S2, covering an antibacterial layer 12; the nonwoven scrim 1 with the development lines 11 after the step S1 is immersed in the antibacterial solution, and the antibacterial layer 12 is formed on the surface of the nonwoven scrim 1 after the antibacterial solution is solidified. The antibacterial liquid is a calcium alginate solution containing silver ions, the concentration of the silver ions is 55-70%, and the concentration of the silver ions is preferably 70%, so that the formed antibacterial layer 12 is high in antibacterial and antivirus performance, and the antibacterial layer 12 and the non-woven gauze 1 are high in combination degree and not easy to fall off.
S3, covering the liquid absorbing layer 13; the nonwoven scrim 1 with the development lines 11 and the antibacterial layer 12 after the step S2 is dipped in the mixed liquid, and the liquid absorbent layer 13 is formed on the surface layer of the antibacterial layer 12 after the mixed liquid is solidified. The liquid mixture is formed by mixing super absorbent resin and sodium alginate according to the proportion of 2:1, so that the formed liquid absorption layer 13 has extremely high liquid absorption capacity, and the liquid absorption layer 13 and the antibacterial layer 12 have high combination degree and are not easy to fall off.
S4, punching the accommodating groove 14; the punching mechanism 61 is used for punching a plurality of accommodating grooves 14 uniformly on one side, away from the developing line 11, of the nonwoven gauze 1 with the developing line 11, the antibacterial layer 12 and the liquid absorbing layer 13 after the step S3, and the accommodating grooves 14 are uniformly distributed between two adjacent developing lines 11, so that the accommodating grooves 14 are formed on the nonwoven gauze 1 by adopting a punching mode, cutting is not needed, and operation is convenient.
S5, adding a hemostatic agent 15; the hemostatic agent 15 is added into the container 14 punched and formed in step S4, and the hemostatic agent 15 is one of hemostatic particles, hemostatic powder, or hemostatic gel.
S6, compounding absorbent gauze 16; the absorbent gauze 16 is covered on the surface of the nonwoven gauze 1 passing through the step S5, the absorbent gauze 16 covers the opening of the containing groove 14, and the absorbent gauze 16 and the nonwoven gauze 1 are fixed in a composite manner to form the composite dressing.
S7, slitting and packaging; and cutting the composite dressing prepared in the step S6 into a required shape and packaging to finish the preparation of the medical dressing. Wherein, the medical auxiliary materials with the shapes of round, rectangle, rhombus, triangle and the like can be cut according to the actual requirement.
S8, sterilizing and warehousing; and (5) performing ray radiation sterilization on the medical dressing prepared in the step S7, and storing in a warehouse after sterilization is completed.
Production equipment for medical developing dressingAs shown in fig. 2, the method includes the developing-line dispensing device 4 used in step S1, steps S2, andthe coating device 5 used in the step S3 and the filling device 6 used in the steps S4-S6 are that the coating device 5 is used for coating the antibacterial layer 12 and the liquid absorbing layer 13 to form a continuous production line, and the stamping accommodating groove 14, the hemostatic 15 and the composite absorbent gauze 16 are used for filling the filling device 6 to form a continuous production line, so that the equipment is simplified to form a continuous production line, the production efficiency is improved, and the equipment is simplified. The cutting, packaging and sterilizing equipment can directly use the equipment in the prior art, so the description is not repeated.
The specific structures of the developing line dripping device 4, the coating device 5 and the medicine filling device 6 are described below, wherein the three devices all use the material discharging frame 2 for discharging and the material receiving frame 3 for receiving, and have the same structure and the same function, so the same names are used.
As shown in fig. 3, the developing line dripping and fixing device 4 includes a material placing frame 2, a material guiding frame 41, a dripping frame 42, an extruding frame 43, a thermosetting box 44, a buffering frame 45 and a material receiving frame 3, which are sequentially arranged along a feeding direction, a plurality of guide rollers 46 horizontally arranged perpendicular to the feeding direction are respectively arranged on the material guiding frame 41 and the buffering frame 45, the guide rollers 46 are vertically staggered, and the non-woven gauze 1 is conveyed forward in an S shape around the guide rollers 46.
As shown in fig. 3 and 4, a heating tank 421 containing a developing solution is placed on the dropping rack 42, and the developing solution is kept in a molten state by the heating tank 421, so that the developing solution can be dropped conveniently. The dripping frame 42 is further provided with an installation rod 422 arranged along the length direction of the guide roller 46 and a support plate 423 positioned below the installation rod 422, the installation rod 422 is provided with three dripping heads 424 uniformly arranged right above the support plate 423 along the length direction, the dripping heads 424 respectively correspond to two side edges and a center line of the non-woven gauze 1, and the dripping heads 424 are communicated with the heating tank 421 through a pipeline and are provided with speed regulating valves. The dropping head 424 drops the developing solution in the heating tank 421 onto the nonwoven gauze 1, and the dropping speed of the developing solution can be adjusted by using a speed adjusting valve. Wherein, the non-woven gauze 1 is on the supporting plate 423 when the developing solution is dripped, so that the developing solution can be prevented from flowing.
As shown in fig. 4, two pressure rollers 431 which are vertically symmetrically arranged and parallel to the guide roller 46 are rotatably positioned on the pressing frame 43, and the upper end surfaces of the support plates 423 are located on the symmetrical plane of the two pressure rollers 431. The nonwoven scrim 1 is flatly placed between the two pressing rollers 431 on the pressing frame 43 from the supporting plate 423, and the developing solution flattened into a linear shape is coated on the surface of the nonwoven scrim 1 by the pressing of the two pressing rollers 431. In which an anti-sticking layer may be provided on the pressure roller 431 to prevent the developer from adhering to the pressure roller 431.
As shown in fig. 4, a plurality of distance-increasing rollers 441 parallel to the guide roller 46 are arranged in the thermosetting box 44 along the length direction of the thermosetting box, three layers are arranged above and below the distance-increasing rollers 441, the non-woven gauze 1 extruded by the two press rollers 431 enters the thermosetting box 44 and then passes by the distance-increasing rollers 441 in an S shape, and the distance-increasing rollers 441 are arranged below the non-woven gauze 1, so that the stroke of the non-woven gauze 1 in the thermosetting box 44 is increased, the thermosetting time of the developing thread 11 on the non-woven gauze 1 is prolonged, and the fixing effect of the developing thread 11 on the non-woven gauze 1 is ensured. Of course, a reversing roll is provided in the heat setting tank 44 to ensure that the nonwoven scrim 1 can be transported forward along the extended-range roll 441 in an S-shaped path.
As shown in fig. 4, a plurality of air heaters 442 are uniformly provided in the heat curing tank 44, and the developer is heated by the air heaters 442 to accelerate the solidification of the developer. Wherein, the middle temperature in the thermosetting box 44 is higher than the two ends temperature, which provides the relaxation time for the heating of the developing solution and ensures the forming effect of the developing line 11.
As shown in fig. 3 and 4, the nonwoven gauze roll to be processed is mounted on the material-placing frame 2 for placing material, the material-guiding frame 41 plays a role of guiding material and also playing a role of buffering, so as to prevent the nonwoven gauze 1 from being stacked on the liquid dropping frame 42, the liquid dropping head 424 at the liquid dropping frame 42 drops the molten developing solution in the heating tank 421 onto the nonwoven gauze 1, then the nonwoven gauze 1 is sent to the extrusion frame 43, the two compression rollers 431 perform physical extrusion molding on the nonwoven gauze, then the nonwoven gauze is sent into the thermosetting box 44 for thermosetting molding, the nonwoven gauze is sent out from the thermosetting box 44, then the stroke heat dissipation is increased through the buffer frame 45, and finally the nonwoven gauze 1 is wound by the material-receiving frame 3, so as to complete the fixation between the developing line 11 and the nonwoven gauze 1.
As shown in fig. 5, the coating device 5 includes a material placing frame 2, an antibacterial liquid box 51, a drying box 52, a mixed liquid box 53, a drying box 54 and a material receiving frame 3 which are sequentially arranged along the feeding direction, the antibacterial liquid box 51 is filled with antibacterial liquid, the mixed liquid box 53 is filled with mixed liquid, the drying box 52 and the drying box 54 are both infrared bricks for drying, and a plurality of infrared bricks are uniformly arranged along four sides of the length. In addition, a plurality of winding rollers 55 which are horizontally arranged perpendicular to the feeding direction are arranged in the antibacterial liquid tank 51, the drying tank 52, the mixed liquid tank 53 and the drying tank 54 along the length direction of the antibacterial liquid tank, the winding rollers 55 are vertically staggered to form a plurality of layers, and the winding rollers 55 are positioned below the liquid level when in the antibacterial liquid tank 51 and the mixed liquid tank 53, so that the stroke of the non-woven gauze 1 is increased, the soaking and drying time of the non-woven gauze is prolonged, and the forming effect of the antibacterial layer 12 and the liquid absorption layer 13 is ensured.
As shown in fig. 5, a liquid level sensor may be disposed in the antimicrobial liquid tank 51 and the mixed liquid tank 53 above the winding roller 55 from the upper layer, so as to add the antimicrobial liquid and the mixed liquid in time. In order to prevent dust from adhering to the nonwoven fabric during the application of the antibacterial layer 12 and the liquid absorbent layer 13, the antibacterial liquid tank 51, the drying tank 52, the mixed liquid tank 53, and the drying tank 54 are in contact communication with each other in this order.
As shown in fig. 5, the nonwoven gauze roll with the development lines 11 prepared by the development line drip-fixing device 4 is mounted on the material-placing rack 2 for releasing, the nonwoven gauze 1 with the development lines 11 sequentially enters the antibacterial liquid tank 51, the drying tank 52, the mixed liquid tank 53 and the drying tank 54, and is soaked in the antibacterial liquid tank 51, so that the antibacterial liquid soaks the nonwoven gauze 1, and then enters the drying tank 52 for drying, so that the solidification of the antibacterial liquid is accelerated, and the formed antibacterial layer 12 coats the surface layer of the nonwoven gauze 1 and the development lines 11. The nonwoven gauze 1 coated with the antibacterial layer 12 enters the mixed liquid tank 53 to be soaked in the mixed liquid, so that the mixed liquid soaks the nonwoven gauze 1, then enters the drying tank 54 to be dried, so that the solidification of the mixed liquid is accelerated, the formed liquid absorption layer 13 is coated on the outer surface of the antibacterial layer 12, and finally the nonwoven gauze is rolled up by the material collecting rack 3.
As shown in fig. 6, the medicine filling device 6 includes a material placing frame 2, a punching mechanism 61, a medicine adding mechanism 62, a degreasing gauze frame 63, a compound frame 64 and a material receiving frame 3, which are sequentially arranged, the material placing frame 2 is provided with a non-woven gauze roll with a developing line 11, an antibacterial layer 12 and a liquid absorbing layer 13, which is prepared by the coating device 5, and is released, and one side of the non-woven gauze 1 with the developing line 11 faces downwards when released, the punching mechanism 61 punches the accommodating groove 14, the medicine adding mechanism 62 adds a hemostatic 15 into the accommodating groove 14, the degreasing gauze frame 63 is provided with the degreasing gauze roll and is released, the degreasing gauze 16 and the non-woven gauze 1 are compounded and fixed at the compound frame 64, and are finally wound and fixed by the material receiving frame 3. The structure of the absorbent gauze frame 63 is similar to that of the material placing frame 2, and redundant description is omitted.
As shown in fig. 6 and 7, in the present embodiment, the punching mechanism 61 includes a punching stage 611 and a punching frame 612 located above the punching stage 611, a template 613 is detachably mounted on an upper end surface of the punching stage 611, a plurality of concave pits 6131 are arranged in a rectangular array on the template 613, the concave pits 6131 may be in a hemispherical shape, a cylindrical shape, a prismatic shape, or the like, a punching head 614 corresponding to the concave pits 6131 on the template 613 is arranged on the punching frame 612, and the punching head 614 is heated by electricity. When the nonwoven gauze 1 passes through the upper part of the template 613 on the punching table 611, the punching head 614 punches downwards, the concave pits 6131 on the template 613 are matched to punch the nonwoven gauze 1 to form the accommodating groove 14, and the punching head 614 is electrified and heated, so that the punching and shaping of the accommodating groove 14 can be ensured, and the nonwoven gauze 1 at the accommodating groove 14 is prevented from rebounding.
As shown in fig. 6 and 7, the medicine adding mechanism 62 includes a medicine adding rack 621, a medicine tank 622 containing hemostatic 15 is disposed on the medicine adding rack 621, a medicine adding seat 623 is disposed on the medicine adding rack 621, a plurality of medicine adding nozzles 624 communicated with the medicine tank 622 through a pipeline are disposed on the lower end surface of the medicine adding seat 623, and the medicine adding nozzles 624 correspond to the punching heads 614 one by one along the length direction of the medicine adding rack 621, that is, only one row of medicine adding nozzles 624 is provided. After the non-woven gauze 1 is punched, the non-woven gauze continues to move forwards to the position below the medicine adding rack 621, and the plurality of medicine adding nozzles 624 add the hemostatic 15 in the medicine tank 622 into the accommodating groove 14. Of course, the medicine adding nozzle 624 may also be provided with a speed regulating valve for regulating the speed of adding the hemostatic agent 15.
As shown in fig. 6, at least two sets of roller sets 641 are disposed on the composite frame 64 along the feeding direction, in this embodiment, three sets of roller sets are disposed, each set of roller set 641 includes two heat-sealing rollers 6411 disposed vertically and symmetrically and horizontally along the feeding direction, and the heat-sealing roller 6411 located below is provided with a notch matched with the receiving groove 14. In the process that the non-woven gauze 1 is conveyed forwards from the medicine adding rack 621, the non-woven gauze rack 63 is provided with a non-woven gauze roll for releasing, covers the non-woven gauze 1 to block the opening of the accommodating groove 14, moves to the composite rack 64 along with the non-woven gauze 1, penetrates through the heat sealing rollers 6411 in the roller set 641, and is fixed with the non-woven gauze 1 and the non-woven gauze 16 through the heat sealing action of the heat sealing rollers 6411 to form a composite dressing which is wound by the material receiving rack 3.
The developing line dripping device 4, the coating device 5 and the chemical filling device 6 in this embodiment can also be prepared by simultaneously preparing multiple rolls of non-woven gauze rolls, and correspondingly, a corresponding dripping head 424 is added to the developing line dripping device 4, a corresponding template 613 and a corresponding punching head 614 are added to the punching structure, and a corresponding chemical filling nozzle 624 is added to the chemical filling mechanism 62.
While the foregoing description shows and describes the preferred embodiments of the present invention, it is to be understood that the invention is not limited to the forms disclosed herein, but is not to be construed as excluding other embodiments and is capable of use in various other combinations, modifications, and environments and is capable of changes within the scope of the inventive concept as described herein, commensurate with the above teachings, or the skill or knowledge of the relevant art. And that modifications and variations may be effected by those skilled in the art without departing from the spirit and scope of the invention as defined by the appended claims.
Claims (10)
1. A medical development dressing, characterized in that: the non-woven fabric comprises a non-woven gauze (1) and a absorbent gauze (16) which are compounded, wherein at least two developing lines (11) which are parallel to each other and are uniformly arranged are arranged on one side, away from the absorbent gauze (16), of the non-woven gauze (1), an antibacterial layer (12) and a liquid absorption layer (13) which coat the non-woven gauze are arranged on the outer surface layer of the non-woven gauze (1), the antibacterial layer (12) is positioned between the non-woven gauze (1) and the liquid absorption layer (13), and the developing lines (11) are positioned between the antibacterial layer (12) and the non-woven gauze (1); evenly be equipped with a plurality of storage tanks (14) that are located between adjacent development line (11) on non-woven gauze (1), the opening of storage tank (14) is located one side that non-woven gauze (1) is close to absorbent gauze (16), and it is protruding to one side of keeping away from absorbent gauze (16), storage tank (14) intussuseption is filled with hemostatic (15).
2. The medical imaging dressing of claim 1, wherein: the development line (11) is fixed on the surface of the non-woven gauze (1) by adopting a method of dripping molten development liquid, extruding by a compression roller and thermally curing.
3. A preparation method of medical developing dressing is characterized in that: the method comprises the following specific steps:
s1, dropping a developing line (11); fixing a developing line (11) on the non-woven gauze (1) by using a developing line dripping device (4), dripping the molten developing solution onto the non-woven gauze (1), extruding the developing solution into a linear structure by using a compression roller, and solidifying the linear developing solution into the developing line (11) fixed on the non-woven gauze (1) by adopting heat curing;
s2, covering an antibacterial layer (12); immersing the non-woven gauze (1) subjected to the step S1 into an antibacterial solution, and forming an antibacterial layer (12) on the surface layer of the non-woven gauze (1) after the antibacterial solution is solidified;
s3, covering a liquid absorbing layer (13); immersing the nonwoven gauze (1) having undergone step S2 in the mixed solution, and forming a liquid absorbent layer (13) on the surface layer of the antibacterial layer (12) after the mixed solution solidifies;
s4, punching an accommodating groove (14); uniformly punching a plurality of accommodating grooves (14) on one side of the non-woven gauze (1) which passes through the step S3 and is far away from the developing lines (11) by using a punching mechanism (61), wherein the plurality of accommodating grooves (14) are uniformly distributed between two adjacent developing lines (11);
s5, adding a hemostatic agent (15); adding a hemostatic agent (15) into the accommodating groove (14) formed by punching in the step S4, wherein the hemostatic agent (15) is one of blood particles, hemostatic powder or hemostatic gel;
s6, composite absorbent gauze (16); covering absorbent gauze (16) on the surface of the non-woven gauze (1) subjected to the step S5, covering the opening of the accommodating groove (14) with the absorbent gauze (16), and compounding and fixing the absorbent gauze (16) and the non-woven gauze (1) to form a composite dressing;
s7, slitting and packaging; cutting the composite dressing prepared in the step S6 into a required shape and packaging to complete the preparation of the medical dressing;
s8, sterilizing and warehousing; and (5) sterilizing the medical dressing prepared in the step S7, and storing in a warehouse after sterilization.
4. The method for preparing a medical developing dressing according to claim 3, wherein: in the step S2, the antibacterial liquid is a calcium alginate solution containing silver ions, and the concentration of the silver ions is 55% to 70%.
5. The method for preparing a medical developing dressing according to claim 3, wherein: in the step S3, the mixed solution is formed by mixing super absorbent resin and sodium alginate according to the ratio of 2: 1.
6. The production equipment of the medical developing dressing is characterized in that: the method comprises a developing line dripping and fixing device (4) used in the step S1, a coating device (5) used in the steps S2 and S3 and a medicine filling device (6) used in the steps S4-S6, wherein the developing line dripping and fixing device (4), the coating device (5) and the medicine filling device (6) respectively comprise a material placing frame (2) used for placing the non-woven gauze (1) in an unreeling mode and a material receiving frame (3) used for reeling the non-woven gauze (1).
7. The production apparatus of a medical developing dressing according to claim 6, wherein: the developing line dripping and fixing device (4) comprises a material placing frame (2), a material guiding frame (41), a liquid dripping frame (42), an extrusion frame (43), a thermosetting box (44), a buffer frame (45) and a material receiving frame (3) which are sequentially arranged along the feeding direction;
a plurality of guide rollers (46) which are horizontally arranged perpendicular to the feeding direction are respectively arranged on the material guide frame (41) and the buffer frame (45), and the guide rollers (46) are arranged in a vertically staggered manner;
the developing solution dripping device is characterized in that a heating tank (421) for containing developing solution is placed on the liquid dripping frame (42), an installation rod (422) arranged along the length direction of the guide roller (46) and a supporting plate (423) located below the installation rod (422) are further arranged on the liquid dripping frame (42), at least two liquid dripping heads (424) uniformly arranged along the length direction of the installation rod (422) are arranged on the installation rod (422), and the liquid dripping heads (424) are communicated with the heating tank (421) and are provided with speed regulating valves;
two compression rollers (431) which are arranged symmetrically up and down and are parallel to the guide roller (46) are positioned and rotatably mounted on the extrusion frame (43), and the upper end faces of the supporting plates (423) are positioned on the symmetrical planes of the two compression rollers (431);
a plurality of range extending rollers (441) parallel to the guide roller (46) are arranged in the thermosetting box (44) along the length direction of the thermosetting box, and three layers are arranged above and below the range extending rollers (441); a plurality of air heaters (442) are uniformly arranged on the thermosetting box (44), and the temperature in the middle of the thermosetting box (44) is higher than the temperatures at two ends.
8. The production apparatus of a medical developing dressing according to claim 6, wherein: cladding device (5) are including blowing frame (2), antibiotic liquid case (51), stoving case (52), mixing tank (53), drying cabinet (54) and the receipts work or material rest (3) that sets gradually along the direction of feed, all be equipped with around material roller (55) that a plurality of perpendicular to feeding direction levels set up along its length direction in antibiotic liquid case (51), stoving case (52), mixing tank (53) and drying cabinet (54), just it is provided with the multilayer to crisscross from top to bottom around material roller (55).
9. The production apparatus of a medical developing dressing according to claim 6, wherein: the medicine filling device (6) comprises a material placing frame (2), a punching mechanism (61), a medicine adding mechanism (62), a degreasing gauze frame (63), a composite frame (64) and a material receiving frame (3) which are arranged in sequence;
the stamping mechanism (61) comprises a stamping platform (611) and a stamping frame (612) positioned above the stamping platform (611), a template (613) is arranged on the upper end surface of the stamping platform (611), and a stamping head (614) corresponding to the template (613) is arranged on the stamping frame (612);
the medicine adding mechanism (62) comprises a medicine adding frame (621), a medicine tank (622) containing hemostatic (15) is arranged on the medicine adding frame (621), a medicine adding seat (623) is arranged on the medicine adding frame (621), a plurality of medicine adding nozzles (624) communicated with the medicine tank (622) are arranged on the lower end face of the medicine adding seat (623), and the medicine adding nozzles (624) are in one-to-one correspondence with the punching heads (614) along the length direction of the medicine adding frame (621);
at least two groups of roller sets (641) are arranged on the composite frame (64) along the feeding direction, each group of roller sets (641) comprises two heat-sealing rollers (6411) which are symmetrical up and down and horizontally arranged along the feeding direction, and notches matched with the accommodating grooves (14) are arranged on the heat-sealing rollers (6411) below.
10. The production apparatus of a medical developing dressing according to claim 9, wherein: the rectangular array on the template (613) is provided with a plurality of pits (6131), the stamping heads (614) correspond to the pits (6131) on the template (613) one by one, and the stamping heads (614) are electrified and heated.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110725678.6A CN113350045B (en) | 2021-06-29 | 2021-06-29 | Medical developing dressing and preparation method and production equipment thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110725678.6A CN113350045B (en) | 2021-06-29 | 2021-06-29 | Medical developing dressing and preparation method and production equipment thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN113350045A true CN113350045A (en) | 2021-09-07 |
| CN113350045B CN113350045B (en) | 2022-09-23 |
Family
ID=77536975
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110725678.6A Active CN113350045B (en) | 2021-06-29 | 2021-06-29 | Medical developing dressing and preparation method and production equipment thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN113350045B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113616426A (en) * | 2021-10-12 | 2021-11-09 | 三特瑞(南通)医用材料有限公司 | Developing gauze and developing thread sewing device thereof |
| CN113734862A (en) * | 2021-11-03 | 2021-12-03 | 张家港蓝智生物科技有限公司 | Special conveyer belt of medical dressing production |
Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0702938A1 (en) * | 1994-09-23 | 1996-03-27 | Laboratoire Hydrex (Sa) | Single use surgical drape or compress |
| CN1337215A (en) * | 2000-08-07 | 2002-02-27 | 李宝玉 | X-ray development operation gauze and its production equipment |
| CN1683708A (en) * | 2005-03-17 | 2005-10-19 | 李建全 | Hydro-entangled non-woven fabric containing X-ray developer and its producing method |
| CN101658452A (en) * | 2009-08-28 | 2010-03-03 | 稳健实业(深圳)有限公司 | X-ray development material compound device, method and dressing |
| CN101757682A (en) * | 2009-12-31 | 2010-06-30 | 枝江奥美医疗用品有限公司 | Method and equipment for compounding X photodevelopment materials on surface of medical dressings and medical dressings |
| CN104131457A (en) * | 2014-07-16 | 2014-11-05 | 安徽可丽纳米纺织品有限公司 | Preparation method of antibacterial non-woven fabric and dip padding liquid for preparation |
| CN206026745U (en) * | 2016-05-18 | 2017-03-22 | 广东泰宝医疗科技股份有限公司 | Anti bacteria dressing of slowly -releasing |
| CN108836632A (en) * | 2018-04-12 | 2018-11-20 | 奥美医疗用品股份有限公司 | A kind of preparation method and new surgical dressing of new surgical dressing |
| CN109235027A (en) * | 2018-10-17 | 2019-01-18 | 江苏阳光股份有限公司 | A kind of nano silver method for sorting of antibacterial wool fabric |
| CN209405088U (en) * | 2018-12-25 | 2019-09-20 | 南京普诺特科技有限公司 | A kind of antibacterial nonwoven cloth with developing mark |
| CN111685937A (en) * | 2020-06-23 | 2020-09-22 | 江苏省健尔康医用敷料有限公司 | Hemostatic and bactericidal medical dressing and preparation method thereof |
-
2021
- 2021-06-29 CN CN202110725678.6A patent/CN113350045B/en active Active
Patent Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0702938A1 (en) * | 1994-09-23 | 1996-03-27 | Laboratoire Hydrex (Sa) | Single use surgical drape or compress |
| CN1337215A (en) * | 2000-08-07 | 2002-02-27 | 李宝玉 | X-ray development operation gauze and its production equipment |
| CN1683708A (en) * | 2005-03-17 | 2005-10-19 | 李建全 | Hydro-entangled non-woven fabric containing X-ray developer and its producing method |
| CN101658452A (en) * | 2009-08-28 | 2010-03-03 | 稳健实业(深圳)有限公司 | X-ray development material compound device, method and dressing |
| CN101757682A (en) * | 2009-12-31 | 2010-06-30 | 枝江奥美医疗用品有限公司 | Method and equipment for compounding X photodevelopment materials on surface of medical dressings and medical dressings |
| CN104131457A (en) * | 2014-07-16 | 2014-11-05 | 安徽可丽纳米纺织品有限公司 | Preparation method of antibacterial non-woven fabric and dip padding liquid for preparation |
| CN206026745U (en) * | 2016-05-18 | 2017-03-22 | 广东泰宝医疗科技股份有限公司 | Anti bacteria dressing of slowly -releasing |
| CN108836632A (en) * | 2018-04-12 | 2018-11-20 | 奥美医疗用品股份有限公司 | A kind of preparation method and new surgical dressing of new surgical dressing |
| CN109235027A (en) * | 2018-10-17 | 2019-01-18 | 江苏阳光股份有限公司 | A kind of nano silver method for sorting of antibacterial wool fabric |
| CN209405088U (en) * | 2018-12-25 | 2019-09-20 | 南京普诺特科技有限公司 | A kind of antibacterial nonwoven cloth with developing mark |
| CN111685937A (en) * | 2020-06-23 | 2020-09-22 | 江苏省健尔康医用敷料有限公司 | Hemostatic and bactericidal medical dressing and preparation method thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113616426A (en) * | 2021-10-12 | 2021-11-09 | 三特瑞(南通)医用材料有限公司 | Developing gauze and developing thread sewing device thereof |
| CN113734862A (en) * | 2021-11-03 | 2021-12-03 | 张家港蓝智生物科技有限公司 | Special conveyer belt of medical dressing production |
Also Published As
| Publication number | Publication date |
|---|---|
| CN113350045B (en) | 2022-09-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN113350045B (en) | Medical developing dressing and preparation method and production equipment thereof | |
| US11690933B2 (en) | Absorbent aliphatic polyurethane foam product | |
| DE69734282T2 (en) | COMPOSITE MATERIAL FOR ABSORBING AND DISPOSING BODY FLUIDS AND HUMIDITY | |
| US5031418A (en) | Cooling pack | |
| JP6360152B2 (en) | Absorbent foam composite | |
| US4860737A (en) | Wound dressing, manufacture and use | |
| EP0059048A1 (en) | Wound dressing | |
| JP6353030B2 (en) | Method for making an absorbent foam composite | |
| US5977428A (en) | Absorbent hydrogel particles and use thereof in wound dressings | |
| CN101631572B (en) | Silver-containing foam structure | |
| EP0515667A4 (en) | Hydratable iontophoretic bioelectrode and method of preparation | |
| JP2016521218A5 (en) | ||
| US20040243080A1 (en) | Absorbent pads | |
| CN215230677U (en) | Absorbing article | |
| GB2093703A (en) | Wound dressings for burns | |
| KR101831443B1 (en) | Manufacturing machines and method for dried gel sheet and gel sheet manufactured by the same | |
| CN113002094B (en) | Antibacterial and mildewproof material for packaging and preparation method thereof | |
| JPH04224944A (en) | Manufacture of moisture absorptive sheet | |
| KR102080643B1 (en) | Dehumidifying agent, Method for manufacturing Dehumidifying agent | |
| CA1322997C (en) | Cool pack | |
| JPH0558473B2 (en) | ||
| JPH03202150A (en) | Preparation of oxygen absorbent | |
| CN109394422A (en) | A kind of blotting paper and its manufacturing process and equipment | |
| JPS60232935A (en) | Continuous manufacture of contact dehydration sheet | |
| JPH1052638A (en) | Dewatering sheet |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB02 | Change of applicant information | ||
| CB02 | Change of applicant information |
Address after: 226400 industrial concentration area, Xindian Town, Rudong County, Nantong City, Jiangsu Province (No. 18, Hongqiao Road) Applicant after: Nantong Zhende medical supplies Co.,Ltd. Address before: 226400 industrial concentration area, Xindian Town, Rudong County, Nantong City, Jiangsu Province (No. 18, Hongqiao Road) Applicant before: Santerry (Nantong) medical materials Co.,Ltd. |
|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CP01 | Change in the name or title of a patent holder | ||
| CP01 | Change in the name or title of a patent holder |
Address after: 226400 industrial concentration area, Xindian Town, Rudong County, Nantong City, Jiangsu Province (No. 18, Hongqiao Road) Patentee after: Santerui (Nantong) Medical Materials Co.,Ltd. Address before: 226400 industrial concentration area, Xindian Town, Rudong County, Nantong City, Jiangsu Province (No. 18, Hongqiao Road) Patentee before: Nantong Zhende medical supplies Co.,Ltd. |