KR101831443B1 - Manufacturing machines and method for dried gel sheet and gel sheet manufactured by the same - Google Patents

Abstract

The present invention provides a drying gel sheet producing apparatus capable of collecting a hydrogel produced in a continuous sheet shape continuously and drying, a method and a gel sheet produced thereby, and a hydrogel composition contained in the storage tank (24) (2) having a gravure roll (22a) (22b) for applying a hydrogel composition onto a support (M) conveyed together with a lower film (Fa) to form a sheet-like hydrogel (H); A cold drying unit (4) for cooling the sheet-like hydrogel (H) while being cooled by the cold plate (44) to be solidified; And a hot drying unit 6 for ironing the solidified sheet-like hydrogel (H) with a heater roll group (64) and heating and drying the heated gel sheet (H) with a gel sheet. In this apparatus, Applying a gel composition to form a sheet-like hydrogel (H) and depositing and protecting the upper film (Fb) on the upper surface thereof; Passing the sheet-like hydrogel (H) in a low-temperature atmosphere to solidify the sheet-like hydrogel (H); And a hot-drying step of taking over the upper and lower films (Fb) (Fa) from the sheet-like hydrogel (H) solidified by cooling and heating the top and bottom surfaces thereof by ironing to collect the gel sheet (G2) Discloses a method for producing a dry gel sheet and a gel sheet in which the front and back surfaces are coated so as to have a dense density as compared with the center portion.

Description

[0001] The present invention relates to an apparatus and a method for producing a dry gel sheet, and a gel sheet produced thereby,

The present invention relates to an apparatus and a method for manufacturing a dry gel sheet for mass-producing a product made of a hydrogel, and a gel sheet produced thereby.

Polymer hydrogels are widely used for diapers, contact lenses, medical electrodes, cell cultures, and for special applications, they are also widely used for molding materials, soil moisture storage, and wound scarring.

A hydrogel is a hydrophilic polymer crosslinked by cohesive forces by covalent bonding, hydrogen bonding, van der Waals bonding, or physical bonding, and is a material having a three-dimensional polymer network structure capable of swelling a large amount of water contained therein And exhibits a behavior similar to that of a living body in a state of absorbing water.

Once formed as a hydrogel, it is very durable even at a temperature of 90 ° C, and even if deformed due to external force, it is rapidly rearranged to restore its original structure.

Generally, hydrogels are prepared by dissolving polyhydric alcohols such as glycerin, butyleneglycol, carboplatin gum, agar, carrageenan and xanthan gum in water maintained at 90 to 100 ° C as a main component, and adding functional additives Mixed and dispersed to obtain a gel formulation.

However, since the hydrogel contains a large amount of water, its physical properties are weak, and there are many difficulties in manufacturing a product using the hydrogel.

For example, in the process of producing the hydrogel mask pack, the hydrogel to be produced is supplied between two sheets of elastic films, cooled in a state spreading in a sheet form, and then punched out in the form of a mask together with the film in the pressing process .

In such a manufacturing method, the hydrogel punched out in the form of a mask has a poor physical property and must be protected with a film until use, and the manufactured hydrogel mask must be sealed and stored in a pouch or the like.

In order to overcome such disadvantages, the following Patent Document 1 discloses a method of forming a cured film on the surface of a hydrogel, but even if a cured film is added to the hydrogel, the original weak physical properties are not changed at all, none.

On the other hand, when the hydrogel spreads in a sheet form is naturally dried, it becomes easy to cut into an arbitrary shape as a gel sheet. Further, when water is supplied to the cut gel sheet, it swells again and is useful as an original hydrogel.

However, in order to dry the hydrogel naturally, it is not suitable for mass production because it has a large space isolated from the outside, and a lot of time and effort.

The following Patent Document 2 discloses an example in which a hydrogel is prepared by lyophilizing a therapeutic medical article comprising a dry hydrogel of a hydrophilic-hygroscopic polymer such as an unmodified or modified polymeric carbohydrate in the form of a solid foam.

However, the method of freezing the hydrogel by freezing is not easy, and since the frozen water is thawed at room temperature and reabsorbed by the hydrogel, there is a problem that it must be stored in a frozen state.

In the following Patent Document 3, a hyaluronic acid gel sheet obtained by first drying a hydrogel obtained by applying an aqueous solution obtained by dissolving an alkali salt of polymer hyaluronic acid in an alkaline solution in the form of a flat sheet is vacuum-dried in a vacuum oven, and then the aqueous solution of an anhydrous anhydride And then dried in a vacuum oven to prepare a solution, which is then dried in an anhydrous solution diluted with the unit organic acid constituting the solution.

However, since the vacuum oven can not dry a large amount of hydrogel, this method is not suitable for mass production.

Korean Patent Registration No. 10-1372227, Korean Patent Publication No. 10-1995-0705867, Korean Patent Registration No. 10-1597794,

An object of the present invention is to provide a drying gel sheet producing apparatus capable of continuously drying a hydrogel produced in a continuous sheet form.

Another object of the present invention is to provide a manufacturing method using a dry gel sheet manufacturing apparatus for heating and heating the front and back surfaces of a hydrogel produced in a continuous sheet form by ironing and drying the same.

It is still another object of the present invention to provide a gel sheet which is manufactured by the above-described manufacturing method and which is densely formed on the front and back surfaces in comparison with the center side.

The apparatus for producing a dry gel sheet according to the present invention is a device for manufacturing a dry gel sheet according to the present invention, in which a hydrogel of a sheet is formed by coating a hydrogel composition contained in a storage tank with a gravure roll on a support conveyed together with a lower film, ; A cold drying unit for conveying the sheet-like hydrogel protected by the upper and lower films to the lower side of the cold plate to form a sheet-like solidified gel by cooling; A sheet-like solidified gel having the upper and lower films separated therefrom is passed through a heater roll group composed of a plurality of heater rolls provided with nozzle means for supplying hot air inside the hot-rolling housing, so that the front and back surfaces of the sheet- Thereby forming a gel sheet.

The method for producing a dry gel sheet according to the present invention comprises a coating step of applying a hydrogel composition to a support fed on a lower film and attaching an upper film and protecting the upper film with a sheet-like hydrogel; A cold drying step in which the sheet-like hydrogel is made into a sheet-like solidified gel in a low-temperature atmosphere, a hot-drying step in which the upper and lower films are peeled off from the cooled sheet-like solidified gel and the front and back surfaces are ironed and collected into a dried gel sheet .

Also, in the above-described method for producing a dry gel sheet by the production apparatus of the present invention, the release sheet may be attached to the upper surface of the sheet-like solidified gel from which the upper and lower films have been peeled off.

Further, the gel sheet of the present invention is characterized in that the front and back surfaces or the back surface are ironed by the above-described manufacturing method so as to form a film with a dense density than the center portion.

The above-described apparatus for producing a dry gel sheet of the present invention is one in which a gravure roll continuously applies a hydrogel composition to the front and back surfaces of a support, and the cold plate is a low temperature- The heating roller group has a structure in which a sheet-like solidifying gel is taken in a state in which the upper and lower films are peeled off and ironed and dried by hot air drying to complete drying, so that a gel sheet based on a hydrogel can be continuously produced, .

The manufacturing method using the drying gel sheet producing apparatus of the present invention is characterized in that the hydrogel applied between the upper and lower films is cooled at a low temperature and converted into a sheet-like solidified gel, the upper and lower films are peeled off, There is an advantage in that the density of the front and back surfaces or the back surface becomes dense as compared with the center side in which the support body is embedded by heating and drying, thereby continuously providing the gelated gelatin sheet.

The gel sheet obtained by the dry gel sheet production method of the present invention is denser than the center side in density of the coated portion on the front and back surfaces even when the gel sheet is immersed in a drug or cosmetic ingredient and swelled with the original hydrogel Therefore, when adhering to the skin, evaporation of the drug or cosmetic ingredient through the surface of the hydrogel is suppressed, and the drug or cosmetic ingredient acts on the skin for a sufficient time.

1 is a schematic structural view of a drying gel sheet producing apparatus according to the present invention.
Fig. 2 is an enlarged view showing a state in which a hydrogel is applied by the gravure roll shown in Fig. 1; Fig.
3 is an enlarged cross-sectional view of a portion "A"
Fig. 4 is a photograph of a part "A"
5 is a photograph of a portion "B"
6 is an enlarged cross-sectional view of a portion "B"
Fig. 7 is a side view showing another arrangement example relating to the heating roller group of Fig. 1; Fig.
Fig. 8 is a side view showing still another arrangement example of the heating roller group of Fig. 1; Fig.
9 is a side view of a main portion of a drying gel sheet producing apparatus according to another embodiment of the present invention.
10 is an enlarged cross-sectional view of the portion "C" in Fig.

Hereinafter, an apparatus and method for producing a dry gel sheet of the present invention and a gel sheet produced thereby will be described in detail with reference to the accompanying drawings.

Fig. 1 shows a drying gel sheet producing apparatus according to the present invention, which comprises a coating section 2, a cold drying section 4, and a hot-air drying section 6. As shown in Fig.

The application section 2 is constituted by a plurality of guide rolls 20, gravure rolls 22a and 22b and a reservoir 24 containing a hydrogel aqueous solution H.

The cold drying unit 4 is divided into a cold housing 40 having an inlet and an outlet on both sides thereof and a conveyor 42 disposed on an inner bottom surface of the cold housing 40. A cold plate 44, And a facility required for low-temperature cooling such as the ventilator 46 is disposed.

The hot dry unit 6 is also divided into a hot housing 60 having an inlet and an outlet on both sides and a heater roll group 64 in which a plurality of heater rolls 62 are continuously arranged.

A nozzle means 66 for supplying hot air is disposed between the heater rolls 62 of the heater roll group 64 to promote the drying of the hydrogel.

In the heater roll group 64, it is preferable that the heater rolls 62 are maintained at a temperature of 70 to 80 ° C, and hot air blown through the nozzle means 66 is maintained at a temperature of 180 to 200 ° C.

According to the above-described manufacturing apparatus, in the application unit 2, a plurality of guide rolls 20 are guided in a state in which the lower film Fa and the support M, which is one of mesh, thin nonwoven fabric and thin cellulose fibrils, And continuously supplied between the gravure rolls 22a and 22b.

On the other hand, the reservoir 24 containing the hydrogel composition in an aqueous solution state is heated to 75 to 100 캜 and is always kept in a fluid state, so that the hydrogel composition is supplied to both gravure rolls 22a (22b), and the thickness of the sheet-like hydrogel (H) is adjusted by passing through the surface of the sheet-like hydrogel (H) to form a sheet-like hydrogel (H) Is carried on the lower film (Fa) including the support (M).

In the present invention, the hydrogel composition may be added to purified water in the purified water in such a manner that it is added to purified water in the order of konnyaku, carrageenan, gellan gum, carboplatin gum, gelatin, agar, collagen, hyaluronic acid, acacia gum, arabia gum, starch, pullulan, galactomannan, , Algin, xanthan gum, pectin, and natural polymers made of cellulose.

As described above, the upper surface of the sheet-like hydrogel H transported on the lower film Fa moves while being covered with the upper film Fb fed along the guider 26.

As a result, the sheet-like hydrogel (H) has a single-layer structure protected by the upper and lower films (Fb) (Fa) as shown in Fig. 3 and passed through the subsequent cold-drying section (4).

The sheet-like hydrogel H is in a state in which the moisture on the upper surface (the bottom surface of the upper film Fb) can be visually confirmed before the sheet-like hydrogel H enters the cold-drying unit 4, as shown in the photograph of FIG.

The sheet-like hydrogel (H) is rapidly cooled while the inside of the cold housing (40) of the cold dryer (4) is kept in the range of -20 to -5 ° C, .

When the sheet-like solidifying gel G1 is released from the cold housing 40, the upper film Fb covering the upper surface of the sheet-like solidifying gel G1 is peeled off and removed continuously with the lower film Fa together with the hot- 60).

In order to prevent surface damage of the sheet-like solidifying gel G1 in the peeling process, it is necessary to peel off the lower film Fa at the beginning of the hot-rolling housing 60, ) Is most effective.

The sheet-like solidifying gel G1 from which the lower film Fa has been peeled off is then passed between the heater rolls 62 of the heater roll group 64.

In this process, since the plurality of heater rolls 62 constituting the heater roll group 64 are arranged so as to be shifted from each other, the sheet-like solidifying gel G1 passing therethrough always passes between the pair of heater rolls 62 So that the vehicle can be driven at a high speed while maintaining a constant tension.

In addition, the heater rolls 62 disposed mutually shifted can set the drying course for the sheet-like solidifying gel G1 to be long, but the actual length is greatly reduced, thereby reducing the size of the entire equipment.

On the other hand, since the arrangement pattern of the heater rolls 62 greatly affects the resistance of the sheet-like solidifying gel G1, it is preferable to reduce the resistive force as much as possible so that cutting or partial breakage does not occur during traveling, , The ironing effect of the sheet-like solidifying gel G1 is deteriorated, so that it is necessary to harmonize both of them.

In the present invention, the heater rolls 62 of the heater rolls 64 arranged in two rows are arranged in a substantially delta shape so that the sheet-like solidifying gel G1 in running is sufficiently in contact with each heater roll 62, "He said.

As described above, when the sheet-like solidifying gel G1 is passed through the heater roll group 64, the surface and the back surface thereof are alternately brought into contact with the heater roll 62, heated and dried, and the surface is pulled by the resistance during running It is ironed.

With the above-described ironing, warm air is sprayed through the nozzle means 66 and drying is promoted, so that the sheet-like solidifying gel G1 is completely dried with the gel sheet G2 to be discharged from the hot housing 60.

The completely dried gel sheet G2 has a thin sheet form in which the mesh pattern of the support M contained therein is exposed as shown in the photograph of FIG.

The production method of the present invention using the dry gel sheet production apparatus having the above-mentioned structure is a method in which a hydrogel composition is applied to a support M supplied with a lower film Fa to form a sheet, and an upper film Fb ) To cover and protect it; A cold drying step in which the sheet-like hydrogel is cooled in a low-temperature atmosphere to form a sheet-like solidifying gel (G1), and an upper and a lower film (Fa) are peeled from the sheet-like solidifying gel (G1) Drying step in which hot air drying is performed while passing through the heater roll group 64, and the front and back surfaces are ironed and collected with the densely dried gel sheet G2.

The gel sheet G2 of the present invention obtained by the above-mentioned dry gel sheet manufacturing method is obtained by passing the gel sheet G2 through the hot housing 60 by ironing through the heater rolls 62, (Ga) (Gb) by densely smoothing the density of the front and back surfaces as compared with the center side close to the support M as shown in Fig.

The film formation (Ga) (Gb) exists as a part which is not recognized visually in the real part of FIG. 5, and this is formed in a cross section with a decreased void distribution, resulting in a reduction in the amount of passing water particles per hour, Shows a phenomenon that when a gel sheet (G2) is immersed in a specific drug or cosmetic ingredient and returned to the original hydrogel state, the contained drug or cosmetic ingredient is inhibited from evaporating through the surface.

The gel sheet (G2) according to the present invention exhibits an evaporation inhibiting effect through the surface is confirmed by the following comparative example.

[ Comparative Experimental Example ]

A sample of the gel sheet (G2) according to the present invention is immersed in 20 g of purified water and swollen for 15 minutes to obtain a hydrogel obtained as a sample.

Next, a hydrogel obtained by preparing the same components as the gel sheet (G2) in a conventional manner is cut to the same size to prepare a comparative sample.

The sample and the comparative sample were weighed under the same conditions and placed in a drying weight loss tester of RADWAG WAGI Elektroniczne, model MAC 50 / NH, and the weight The change was converted to a percentage and the results are shown in Table 1 below.

Water Evaporation Rate (Unit:%) time The sample of the present invention Conventional comparative samples 5 minutes 1.71 2.96 10 minutes 3.47 6.15 20 minutes 6.98 12.62 30 minutes 10.45 18.69 45 minutes 15.59 28.04 60 minutes 20.77 37.07 75 minutes 25.87 45.87 90 minutes 31.05 54.51

 As can be seen in Table 1, the evaporation rate of the samples of the present invention increased from 1.76 to 3.51 to 3.47 to 5.14 to 5.18 to 5.1 to 5.18 over time, 3.19-> 6.47-> 6.07-> 9.35-> 9.03-> 8.8-> 8.64, which was higher than the sample of the present invention.

The reason why the evaporation rate of the gel sheet according to the present invention is low is that the density of the ironed front and back surfaces becomes more dense than that of the center side, and the amount of water passing therethrough decreases as the internal void decreases, thereby suppressing evaporation.

In the case of storing the gel sheet (G2) obtained by the above-mentioned production method of the present invention for a long period of time, there is a possibility that a portion which is unintentionally joined to the mutually contacting surface may be formed. Is recommended.

On the other hand, the above-mentioned problem can be solved by covering the releasing paper Gc with the upper surface of the sheet-like solidifying gel G1 from which the upper film Fb has been peeled off from the cold drying section 4, as shown in Fig. 7 .

The sheet-like solidifying gel G1 coated with the release paper Gc passes through between the heater rolls 62 and is dried with the gel sheet G2. The cross section of the solidified gel G1 is, as shown in Fig. 8, It is necessary to provide the front and back surfaces so that the front and back surfaces can be distinguished from each other since only the bottom surface on which the lower film Fa is peeled is made into a film (Gb).

In other words, when used as a bandage mask or face mask, it is recommended to use the uncovered upper face in contact with the skin.

In the manufacturing apparatus of the present invention described above, the arrangement of the heater roll group 64 is not limited to the illustrated embodiment, and may be changed as necessary.

9 shows another example of the arrangement of the heater rolls 64. Two heater rolls 62 arranged in pairs are arranged vertically in two rows in the vertical direction and even in accordance with this structure, Since the gel G1 has a structure in which the front and back surfaces thereof are sufficiently in contact with the heater roll 62 while receiving the minimum resistance, the completely dried gel sheet G2 can be manufactured at a high speed.

Also, the gel sheet G2 can be similarly manufactured at high speed even if the sheet-like solidifying gel G1 is arranged so as to travel while winding a half of each heater roll 62 as shown in Fig.

The gel sheet according to the present invention can be expected to improve the pharmacological effect of the trauma treatment agent and the cosmetic effect due to the cosmetic ingredient supplied to the skin, when the gel sheet is used in a state of being dry, such as a patch or patch for face treatment or a face mask .

2:
20: guide rolls 22a and 22b: gravure roll
24: storage tank 26: guider
4: Cold drying section
40: cold housing 42: conveyor
44: cold plate 46: ventilator
6:
60: hot housing 62: heater roll
64: heater roll group 66: nozzle means
Fa, Fb: Lower and upper film G1: Sheet-like solidifying gel
G2: Gel sheet Gc: Release sheet
Ga, Gb: film-forming H: sheet-like hydrogel
M: Support

Claims (5)

And a gravure roll 22a or 22b for applying the hydrogel composition contained in the reservoir 24 onto the support M conveyed together with the lower film Fa, An application section (2) on which the upper film (Fb) is deposited on the upper surface thereof during movement of the gel (H);
A conveyor 42 for conveying the sheet-like hydrogel H protected by the upper and lower films Fb and Fa is disposed on the bottom of the cold housing 40, A cold drying unit 4 in which a cold plate 44 for cooling the gel H to become a sheet-like solidifying gel G1 is arranged;
A heater roll group 64 composed of a plurality of heater rolls 62 and a nozzle means 66 for supplying warm air between the heater rolls 62 are provided in the interior of the hot housing 60. The upper and lower films Fb, (6) passing the peeled sheet-like solidifying gel (G1) through the heater rolls (64) and heating and drying the surface of the sheet by ironing and hot air to form a gel sheet (G2)
Dried gel sheet. Applying a hydrogel composition to the lower film (Fa) to form a sheet-like hydrogel (H) containing the support (M) and depositing and protecting the upper film (Fb) on the upper surface thereof;
Passing the sheet-like hydrogel (H) in a low-temperature atmosphere to form a sheet-like solidifying gel (G1);
A hot-drying step of ironing the top and bottom surfaces of the sheet-like solidified gel (G1) from which the upper and lower films (Fb) (Fa) have been peeled and heating and drying the same with hot air to obtain a gel sheet (G2);
Of the total weight of the dried gel sheet. 3. The method of claim 2,
The method for manufacturing a dried gel sheet according to claim 1, wherein the sheet-like solidifying gel (G1) is heated and dried in a hot-air drying step after the release paper (Gc) is coated on the upper surface of the sheet-like solidifying gel (G1). delete delete

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