CN111670977A - Qi-regulating spleen-tonifying health-care tea - Google Patents
Qi-regulating spleen-tonifying health-care tea Download PDFInfo
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- CN111670977A CN111670977A CN202010464407.5A CN202010464407A CN111670977A CN 111670977 A CN111670977 A CN 111670977A CN 202010464407 A CN202010464407 A CN 202010464407A CN 111670977 A CN111670977 A CN 111670977A
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Abstract
The invention relates to a health-care beverage, and in particular relates to a qi-regulating and spleen-tonifying health-care tea and a preparation method thereof. The health tea provided by the invention is prepared from medicinal and edible medicinal material extracts and tea leaves according to the weight ratio of 1: 10-10: 1. Wherein the tea leaves are 1-50 parts, and the medicinal material extract is prepared from the following raw materials in parts by weight: 1-5 parts of poria cocos, 1-4 parts of hovenia dulcis thunb, 1-4 parts of orange peel, 0.1-1 part of seville orange flower, 0.1-1 part of liquorice, 1-4 parts of Chinese date, 0.1-1 part of hawthorn and 0.1-1 part of fingered citron.
Description
Technical Field
The invention relates to a health-care beverage, and in particular relates to a qi-regulating and spleen-tonifying health-care tea and a preparation method thereof.
Background
The health tea is firstly a kind of tea, has the color, fragrance and taste of tea, has good taste and delicious taste, is different from common tea and Chinese herbal medicines, but has the property of taking medicines and the taste of drinking tea, and the two medicines are compatible and complement each other to play the role of the synergistic effect of the medicine and the tea-assisting function, and receive the double effects of drinking tea and medicine health care, so the health tea is also a health drink, has the effects of prevention, health care, adjuvant therapy and nourishing on human health, is convenient to drink, has wide application range and has better effect.
Modern people are stressed, the rhythm of life is accelerated, people often work overtime and stay up overnight, and the disease rate of spleen and stomach diseases is increased year by year due to the inattention, epigastric fullness and stuffiness, fullness and pain, heartburn and acid regurgitation, eructation and sighing, poor appetite, abdominal pain and diarrhea, abdominal distension and borborborygmus, emotional irritability, insomnia and dreaminess and other discomfort. At present, spleen and stomach diseases are mostly treated by traditional Chinese medicines or chemical medicines, and the medicines are not good in taste, have side effects, are not suitable for long-term administration, and are not good in patient compliance and easy to relapse.
Therefore, a health care tea with the effects of regulating qi and strengthening spleen is developed.
Disclosure of Invention
Aiming at the defects of the prior art, the invention provides the health-care tea with the effects of regulating qi and strengthening spleen.
The invention adopts the extract of the traditional Chinese medicine used as both medicine and food, the extract is uniformly adhered on the tea leaves, and the appearance with the tea shape is obtained by drying. The tea has improved taste, good appearance, and good taste, and has the fragrance of tea, and can be drunk by patients for a long time, improve appetite, regulate qi-flowing, invigorate spleen, promote digestion, and protect gastric mucosa.
The health tea provided by the invention is prepared from medicinal and edible medicinal material extracts and tea leaves according to the weight ratio of 1: 10-10: 1. Wherein the tea leaves are 1-50 parts, and the medicinal material extract is prepared from the following raw materials in parts by weight: 1-5 parts of poria cocos, 1-4 parts of hovenia dulcis thunb, 1-4 parts of orange peel, 0.1-1 part of seville orange flower, 0.1-1 part of liquorice, 1-4 parts of Chinese date, 0.1-1 part of hawthorn and 0.1-1 part of fingered citron.
Preferably, the health tea provided by the invention is prepared from medicinal and edible medicinal material extracts and tea leaves according to a weight ratio of 1: 5-5: 1, wherein the tea leaves are 3-30 parts, and the medicinal material extract is prepared from the following raw materials in parts by weight: 2-4 parts of poria cocos, 2-3 parts of hovenia dulcis thunb, 2-3 parts of orange peel, 0.5-1 part of seville orange flower, 0.5-1 part of liquorice, 0.5-2 parts of Chinese date, 0.5-1 part of hawthorn and 0.5-1 part of fingered citron.
Preferably, the health tea provided by the invention is prepared from medicinal and edible medicinal material extracts and tea leaves according to a weight ratio of 1: 2, wherein the oolong tea is 30 parts, and the medicinal material extract is prepared from the following raw materials in parts by weight: 3 parts of poria cocos, 4 parts of hovenia dulcis thunb, 3 parts of orange peel, 0.2 part of seville orange flower, 0.3 part of liquorice, 3 parts of Chinese date, 0.5 part of hawthorn and 0.5 part of fingered citron.
More preferably, the health tea provided by the invention is prepared from medicinal and edible medicinal material extracts and black tea in a weight ratio of 2: the composition comprises 5 parts of black tea and a medicinal material extract, wherein the medicinal material extract is prepared from the following raw materials in parts by weight: 2 parts of poria cocos, 2 parts of hovenia dulcis thunb, 2 parts of orange peel, 0.5 part of seville orange flower, 0.5 part of liquorice, 2 parts of Chinese date, 0.5 part of hawthorn and 0.5 part of fingered citron.
The invention combines the research of the traditional Chinese medicine theory, starts from regulating qi and strengthening spleen, uses tuckahoe to promote diuresis and excrete dampness, strengthens spleen, uses orange peel to regulate qi and strengthen spleen, and uses hawthorn to promote digestion and strengthen stomach, removes turbid pathogen and reduces fat, uses hovenia dulcis to quench thirst and relieve restlessness, clears away damp and heat, protects gastric mucosa, uses fingered citron to sooth liver and regulate qi, harmonizes stomach and relieve pain, replaces flowers to regulate qi, widens chest, stimulates appetite, uses Chinese date to tonify middle-jiao and qi, nourishes blood and calms nerves, uses liquorice to tonify spleen and qi, harmonizes the other drugs, and plays the roles of. The fragrance of the black tea is added to activate the spleen and promote digestion. Can effectively stimulate appetite of dyspepsia patients, promote digestion and protect gastric mucosa.
Tuckahoe, poria cocos: dried sclerotium of Poria cocos (Schw.) wolf of Polyporaceae. Sweet, bland and mild. It enters heart, lung, spleen and kidney meridians. Induce diuresis and drain dampness, invigorate spleen and calm heart. Can be used for treating edema, oliguria, phlegm and fluid retention, dizziness, palpitation, spleen deficiency, anorexia, loose stool, diarrhea, uneasiness, palpitation, and insomnia.
Raisin tree seed: dried mature seed of Hovenia dulcis Thunb, a plant of the Rhamnaceae family. Sweet and neutral. It enters heart and spleen meridians. Quench thirst, relieve restlessness, clear away damp-heat and relieve alcoholism. Can be used for treating alcoholism, polydipsia, vomiting, adverse rising of stool, etc.
Orange peel: is dried mature pericarp of Citrus reticulata Blanco of Rutaceae and its cultivar. Bitter, pungent and warm. It enters lung and spleen meridians. Regulate qi to invigorate spleen, dry dampness and resolve phlegm. Can be used for treating abdominal distention, anorexia, vomiting, diarrhea, cough, and excessive phlegm. After stir-frying with bran, the orange peel can reduce the pungent and dry property and relieve the dryness, and can be used for regulating qi and stomach, lowering adverse qi and preventing vomiting.
Licorice root: is dried root and rhizome of Glycyrrhiza uralensis Fisch, Glycyrrhiza inflata Bat or Glycyrrhiza glabra L of Leguminosae. Sweet and neutral. It enters heart, lung, spleen and stomach meridians. Invigorating spleen and replenishing qi, clearing away heat and toxic materials, eliminating phlegm and relieving cough, relieving spasm and pain, and harmonizing the other drugs. Can be used for treating weakness of spleen and stomach, asthenia, palpitation, short breath, cough, excessive phlegm, abdominal and limb spasm, pain, carbuncle, swelling, sore, and drug toxicity and strong nature. After being roasted with honey, the liquorice has the effects of strengthening the spleen and stomach and regulating the middle warmer, and has the effects of tonifying spleen and stomach, tonifying qi and recovering pulse. Can be used for treating weakness of spleen and stomach, asthenia, palpitation, and intermittent pulse.
Chinese date: is dried mature fruit of fructus Jujubae belonging to Rhamnaceae. Sweet and warm. It enters spleen, stomach and heart meridians. Tonify middle-jiao and Qi, nourish blood and soothe the nerves. Can be used for treating spleen deficiency, anorexia, asthenia, loose stool, and hysteria of women. The stir-baked fructus Jujubae is more favorable for invigorating spleen. Substitute flowers: dried flower bud of Citrus aurantium L.var.amara Engl. Sweet, slightly bitter and neutral. Regulating qi-flowing, relieving chest stuffiness, and stimulating appetite. Can be used for treating chest and abdominal distention, nausea, and anorexia.
Hawthorn fruit: is dried mature fruit of plant Crataegus Pinnatifida Bge. Sour, sweet and warm. It enters spleen, stomach and liver meridians. Promoting digestion, invigorating stomach, promoting qi circulation, removing blood stasis, eliminating turbid pathogen, and reducing blood lipid. Can be used for treating meat retention, gastralgia, abdominal pain due to dysentery, amenorrhea due to blood stasis, puerperal blood stasis, cardialgia, thoracic obstruction, cardialgia, hernia pain, and high lipidemia. Stir-baked Haw can eliminate food and regulate middle energizer, and can be used for diarrhea due to spleen deficiency and food stagnation.
Fingered citron: is dried fruit of Rutaceae plant fructus Citri Sarcodactylis Citrus medica L.var.sarcodactylis Swingle, collected in autumn before or after yellowing, longitudinally cut into slices, and dried in the sun or at low temperature. Pungent, bitter, sour and warm. It enters liver, spleen, stomach and lung meridians. Soothe the liver, regulate qi, harmonize stomach, alleviate pain, dry dampness and resolve phlegm. Can be used for treating stagnation of qi of liver and stomach, distending pain in chest and hypochondrium, fullness and distention in stomach, anorexia, emesis, cough, and excessive phlegm.
The qi-regulating and spleen-strengthening tea is based on the recognition and treatment principles of traditional Chinese medicine on spleen deficiency and qi weakness symptoms such as epigastric fullness and stuffiness, fullness and pain, heartburn and acid regurgitation, belching sigh, poor appetite, abdominal pain and diarrhea, abdominal distension and borborygmus, emotional irritability, insomnia and dreaminess and the like caused by spleen deficiency and qi deficiency, and is characterized in that the traditional Chinese medicine with the functions of soothing the liver and regulating qi, strengthening the middle warmer and replenishing qi, promoting qi circulation and nourishing blood and tranquilization, eliminating dampness and removing heat, strengthening the spleen and nourishing the stomach is screened from a Chinese medical treasury, the nature and taste of the traditional Chinese medicine are mutually reinforced, the proportion of the traditional Chinese medicine is regulated to ensure that the extracted extract is fresh, sweet and delicious, the extracted extract can be completely attached to tea leaves, the brewed liquid medicine and tea have attractive appearance, the shape of original tea leaves, and the aroma of the tea leaves is possessed, so that patients can drink well and can use the tea for a long time, meanwhile, the traditional Chinese medicine has the effects of regulating qi, tonifying spleen, helping digestion and protecting gastric mucosa, can be taken for a long time, can sooth liver, regulate qi, strengthen middle-jiao, replenish qi, tonify acquired root, condition five internal organs, prevent gastric ulcer, superficial gastritis and atrophic gastritis, and has better auxiliary curative effects on hypertension, hyperlipidemia and diabetes. The health tea has the advantages of regulating qi-flowing, invigorating spleen, resolving food stagnation, nourishing stomach, quick action, short period, treating both principal and secondary aspect of disease, easy carrying, convenient administration, instant drinking after brewing, good taste, suitability for four seasons, low cost, high cure rate and the like.
The invention also aims to provide a preparation method of the health-care tea.
The preparation method comprises the following steps:
parching pericarpium Citri Tangerinae with bran, parching Glycyrrhrizae radix with Mel, parching fructus Jujubae, parching fructus crataegi, decocting pericarpium Citri Tangerinae, Glycyrrhrizae radix, fructus Jujubae, fructus crataegi and Poria, semen Hoveniae, bitter orange flower and fructus Citri Sarcodactylis in water, concentrating, precipitating with water, concentrating to obtain extract, mixing with folium Camelliae sinensis, adhering the extract to folium Camelliae sinensis, and drying.
Preferably, the preparation method comprises the following steps:
(1) taking hawthorn, putting the hawthorn into a frying container, heating the hawthorn by slow fire until the surface of the hawthorn is slightly yellow, taking out the hawthorn, and cooling the hawthorn;
(2) shredding pericarpium Citri Tangerinae, heating the stir-fried container, adding pericarpium Citri Tangerinae, sieving to remove testa Tritici, and cooling;
(3) taking the Chinese dates, putting the Chinese dates into a frying container, heating the Chinese dates with slow fire until the surfaces of the Chinese dates are slightly yellow, taking the Chinese dates out, and cooling the Chinese dates;
(4) taking liquorice, diluting with boiling water, adding a proper amount of refined honey, uniformly stirring, stewing thoroughly, putting into a frying container, frying with slow fire until the surface is yellowish, taking out, and cooling;
(5) decocting the processed fructus crataegi, pericarpium Citri Tangerinae, fructus Jujubae, Glycyrrhrizae radix, Poria, semen Hoveniae, bitter Citrus aurantium and fructus Citri Sarcodactylis with 8-12 times of water for 1-3 times, mixing decoctions, concentrating to relative density of 1.01-1.25(50 deg.C), adding 1-3 times of water, standing overnight, centrifuging, collecting supernatant, concentrating to relative density of 1.05-1.35(50 deg.C), to obtain Chinese medicinal extract;
(6) putting the tea into a sugar coating pan, adding the Chinese medicinal extract, gently stirring, and standing for about 0.2-2 hr. Opening the sugar coating pan, and stirring continuously until the Chinese medicinal extract is completely absorbed; or placing folium Camelliae sinensis in stainless steel pot, adding the Chinese medicinal extract, standing for 0.1-10 hr, and stirring. Repeating the above steps until the Chinese medicinal extract is completely absorbed. Taking out the tea leaves absorbing the traditional Chinese medicine extract, putting the tea leaves into a forced air drying oven at the temperature of 30-90 ℃ for drying until the surfaces of the tea leaves are dried, cooling and packaging.
Further preferably, the preparation method of the invention comprises the following steps:
(1) taking hawthorn, putting the hawthorn into a frying container, heating the hawthorn by slow fire until the surface of the hawthorn is slightly yellow, taking out the hawthorn, and cooling the hawthorn;
(2) taking and shredding orange peel, heating a frying container until bran is scattered and the orange peel is smoked immediately, immediately adding the orange peel, rapidly turning over, taking out when the surface is yellow or dark yellow, sieving to remove the bran, and cooling, wherein 0.1-0.15 part of the bran is used for every 1 part of the orange peel;
(3) taking the Chinese dates, putting the Chinese dates into a frying container, heating the Chinese dates with slow fire until the surfaces of the Chinese dates are slightly yellow, taking the Chinese dates out, and cooling the Chinese dates;
(4) taking liquorice, diluting with boiling water, adding proper amount of refined honey, uniformly stirring, completely sealing, putting into a frying container, frying with slow fire until the surface becomes yellowish, taking out, cooling, and using 0.25 part of refined honey for every 1 part of liquorice;
(5) decocting the processed fructus crataegi, pericarpium Citri Tangerinae, fructus Jujubae, Glycyrrhrizae radix, Poria, semen Hoveniae, bitter Citrus aurantium and fructus Citri Sarcodactylis with 10 times of water for 2 times, mixing the decoctions for 2 times, concentrating to relative density of 1.01-1.05(50 deg.C), adding 1-3 times of 1-8 deg.C water, standing at 1-5 deg.C for overnight, centrifuging, collecting supernatant, and concentrating to relative density of 1.08-1.15(50 deg.C) to obtain Chinese medicinal extract;
(6) putting the tea into a sugar coating pan, adding the Chinese medicinal extract, gently stirring, and standing for about 0.2-2 hr. Opening the sugar coating pan, and stirring continuously until the Chinese medicinal extract is completely absorbed; or placing folium Camelliae sinensis in stainless steel pot, adding the Chinese medicinal extract, standing for 0.1-10 hr, stirring, and repeating above steps until the Chinese medicinal extract is completely absorbed. Taking out the tea leaves absorbing the traditional Chinese medicine extract, putting the tea leaves into a forced air drying oven at the temperature of 30-90 ℃ for drying until the surfaces of the tea leaves are dried, cooling and packaging.
According to one embodiment, the health tea is prepared from the following raw materials:
2 parts of poria cocos, 2 parts of hovenia dulcis thunb, 2 parts of orange peel, 0.5 part of seville orange flower, 0.5 part of liquorice, 2 parts of Chinese date, 0.5 part of hawthorn, 0.5 part of fingered citron and 5 parts of black tea.
The method comprises the following steps:
(1) taking the hawthorn, putting the hawthorn into a frying container, heating the hawthorn by slow fire until the surface is slightly yellow, taking out the hawthorn, and cooling the hawthorn.
(2) Shredding pericarpium Citri Tangerinae, heating the parching container until testa Tritici is scattered, immediately smoking, adding pericarpium Citri Tangerinae, rapidly turning, parching until surface is yellow or dark yellow, taking out, sieving to remove testa Tritici, and cooling. 0.1-0.15 part of bran is used for every 1 part of orange peel.
(3) Taking the Chinese dates, putting the Chinese dates into a frying container, heating the Chinese dates with slow fire until the surfaces of the Chinese dates are slightly yellow, taking the Chinese dates out, and cooling the Chinese dates.
(4) Taking liquorice, diluting with boiling water, adding a proper amount of refined honey, uniformly stirring, completely sealing, putting into a frying container, frying with slow fire until the surface is yellowish, taking out, and cooling. 0.25 portion of refined honey is used for every 1 portion of liquorice.
(5) Decocting the processed fructus crataegi, pericarpium Citri Tangerinae, fructus Jujubae, Glycyrrhrizae radix, Poria, semen Hoveniae, bitter Citrus aurantium flower and fructus Citri Sarcodactylis with 10 times of water for 2 times, mixing the decoctions for 2 times, concentrating until the relative density is 1.01-1.25(50 deg.C), adding 1-3 times of 1-8 deg.C water, standing at 1-5 deg.C overnight, centrifuging, collecting supernatant, and concentrating to obtain Chinese medicinal extract.
(6) Placing folium Camelliae sinensis in stainless steel pot, adding the Chinese medicinal extract, standing for 30 min, and stirring. Repeating the above steps until the Chinese medicinal extract is completely absorbed. Taking out the tea leaves absorbing the traditional Chinese medicine extract, putting the tea leaves into a forced air drying oven at the temperature of 30-90 ℃ for drying until the surfaces of the tea leaves are dried, cooling and packaging.
According to the second embodiment, the health tea is prepared from the following raw materials: 3 parts of poria cocos, 4 parts of hovenia dulcis thunb, 3 parts of orange peel, 0.2 part of seville orange flower, 0.3 part of liquorice, 3 parts of Chinese date, 0.5 part of hawthorn, 0.5 part of fingered citron and 30 parts of oolong tea. The method comprises the following steps:
(1) taking the hawthorn, putting the hawthorn into a frying container, heating the hawthorn by slow fire until the surface is slightly yellow, taking out the hawthorn, and cooling the hawthorn.
(2) Shredding pericarpium Citri Tangerinae, heating the parching container until testa Tritici is scattered, immediately smoking, adding pericarpium Citri Tangerinae, rapidly turning, parching until surface is yellow or dark yellow, taking out, sieving to remove testa Tritici, and cooling. 0.1-0.15 part of bran is used for every 1 part of orange peel.
(3) Taking the Chinese dates, putting the Chinese dates into a frying container, heating the Chinese dates with slow fire until the surfaces of the Chinese dates are slightly yellow, taking the Chinese dates out, and cooling the Chinese dates.
(4) Taking liquorice, diluting with boiling water, adding a proper amount of refined honey, uniformly stirring, completely sealing, putting into a frying container, frying with slow fire until the surface is yellowish, taking out, and cooling. 0.25 portion of refined honey is used for every 1 portion of liquorice.
(5) Mixing the processed fructus crataegi, pericarpium Citri Tangerinae, fructus Jujubae, Glycyrrhrizae radix, Poria, semen Hoveniae, bitter Citrus immature flower and fructus Citri Sarcodactylis, adding 10 times of water, boiling for 2 times, mixing the decoctions for 2 times, concentrating to relative density of 1.01-1.25(50 deg.C), adding 1-3 times of 1-8 deg.C water, standing at 1-5 deg.C for 24 hr, and collecting supernatant for concentrating to obtain extract.
(6) Putting the tea leaves into a BY-400 water chestnut type sugar coating pan, adding the traditional Chinese medicine extract, gently stirring uniformly, and standing for about 1 h. Opening the sugar coating pan, and stirring continuously until the Chinese medicinal extract is completely absorbed. Taking out the tea leaves absorbing the traditional Chinese medicine extract, putting the tea leaves into a forced air drying oven at the temperature of 30-90 ℃ for drying until the surfaces of the tea leaves are dried, cooling and packaging.
The invention also aims to provide application of the health-care tea in preparing a medicine for regulating qi and strengthening spleen.
The health tea is applied to preparing medicines for tonifying spleen and nourishing stomach, protecting gastric mucosa, treating functional dyspepsia and improving appetite of patients.
Through deep research and by applying the theory of traditional Chinese medicine, the qi-regulating and spleen-strengthening tea screens out the medicine-food dual-purpose traditional Chinese medicine with the functions of soothing liver, regulating qi, strengthening middle warmer, replenishing qi, strengthening spleen, nourishing stomach, nourishing blood, calming heart and soothing nerves, and the raw materials of the components are combined according to a specific proportion to achieve better effects of strengthening spleen, helping digestion and protecting gastric mucosa.
Drawings
FIG. 1 is a graph comparing the effective rates of qi-regulating and spleen-invigorating tea and appetizing and spleen-invigorating pills
The specific implementation mode is as follows:
the invention is further illustrated by the following specific examples, which are not to be construed as limiting the invention.
Example 1 health tea (herbal extract: oolong tea ═ 1: 3)
The qi-regulating spleen-strengthening tea is prepared from the following raw materials in parts by weight: 2 parts of poria cocos, 2 parts of hovenia dulcis thunb, 2 parts of orange peel, 0.5 part of seville orange flower, 0.5 part of liquorice, 2 parts of Chinese date, 0.5 part of hawthorn, 0.5 part of fingered citron and 30 parts of oolong tea. The method comprises the following steps:
(1) taking the hawthorn, putting the hawthorn into a frying container, heating the hawthorn by slow fire until the surface is slightly yellow, taking out the hawthorn, and cooling the hawthorn.
(2) Shredding pericarpium Citri Tangerinae, heating the parching container until testa Tritici is scattered, immediately smoking, adding pericarpium Citri Tangerinae, rapidly turning, parching until surface is yellow or dark yellow, taking out, sieving to remove testa Tritici, and cooling. 0.1-0.15 part of bran is used for every 1 part of orange peel.
(3) Taking the Chinese dates, putting the Chinese dates into a frying container, heating the Chinese dates with slow fire until the surfaces of the Chinese dates are slightly yellow, taking the Chinese dates out, and cooling the Chinese dates.
(4) Taking liquorice, diluting with boiling water, adding a proper amount of refined honey, uniformly stirring, completely sealing, putting into a frying container, frying with slow fire until the surface is yellowish, taking out, and cooling. 0.25 portion of refined honey is used for every 1 portion of liquorice.
(5) Decocting the processed fructus crataegi, pericarpium Citri Tangerinae, fructus Jujubae, Glycyrrhrizae radix, Poria, semen Hoveniae, bitter Citrus immature flower and fructus Citri Sarcodactylis with 10 times of water for 2 times, mixing the decoctions for 2 times, concentrating until the relative density is 1.01-1.05(50 deg.C), adding 1-3 times of 1-8 deg.C water, standing at 1-5 deg.C for 24 hr, sucking supernatant, and concentrating until the relative density is 1.08-1.15(50 deg.C), to obtain 10 parts of Chinese medicinal extract.
(6) Taking black tea and oolong tea, putting into a stainless steel pot, adding the traditional Chinese medicine extract, standing for 30 minutes, and continuously stirring. Repeating the above steps until the Chinese medicinal extract is completely absorbed. Taking out the tea leaves absorbing the traditional Chinese medicine extract, putting the tea leaves into a forced air drying oven at the temperature of 30-90 ℃ for drying until the surfaces of the tea leaves are dried, cooling and packaging.
Example 2 health tea (extract of medicinal materials: oolong tea ═ 1: 2)
The qi-regulating spleen-strengthening tea is prepared from the following raw materials in parts by weight: 3 parts of poria cocos, 4 parts of hovenia dulcis thunb, 3 parts of orange peel, 0.2 part of seville orange flower, 0.3 part of liquorice, 3 parts of Chinese date, 0.5 part of hawthorn, 0.5 part of fingered citron and 30 parts of oolong tea. The method comprises the following steps:
(1) taking the hawthorn, putting the hawthorn into a frying container, heating the hawthorn by slow fire until the surface is slightly yellow, taking out the hawthorn, and cooling the hawthorn.
(2) Shredding pericarpium Citri Tangerinae, heating the parching container until testa Tritici is scattered, immediately smoking, adding pericarpium Citri Tangerinae, rapidly turning, parching until surface is yellow or dark yellow, taking out, sieving to remove testa Tritici, and cooling. 0.1-0.15 part of bran is used for every 1 part of orange peel.
(3) Taking the Chinese dates, putting the Chinese dates into a frying container, heating the Chinese dates with slow fire until the surfaces of the Chinese dates are slightly yellow, taking the Chinese dates out, and cooling the Chinese dates.
(4) Taking liquorice, diluting with boiling water, adding a proper amount of refined honey, uniformly stirring, completely sealing, putting into a frying container, frying with slow fire until the surface is yellowish, taking out, and cooling. 0.25 portion of refined honey is used for every 1 portion of liquorice.
(5) Decocting the processed fructus crataegi, pericarpium Citri Tangerinae, fructus Jujubae, Glycyrrhrizae radix, Poria, semen Hoveniae, bitter Citrus immature flower and fructus Citri Sarcodactylis with 10 times of water under slight boiling for 2 times, mixing the decoctions for 2 times, concentrating to relative density of 1.01-1.05(50 deg.C), adding 1-3 times of 1-8 deg.C water, standing at 1-5 deg.C for 24 hr, sucking supernatant, and concentrating to relative density of 1.08-1.15(50 deg.C) to obtain 15 parts of Chinese medicinal extract.
(6) Putting into BY-400 water chestnut type sugar coating pan, adding the Chinese medicinal extract, gently stirring, and standing for about 1 hr. Opening the sugar coating pan, and stirring continuously until the Chinese medicinal extract is completely absorbed. Taking out the tea leaves absorbing the traditional Chinese medicine extract, putting the tea leaves into a forced air drying oven at the temperature of 30-90 ℃ for drying until the surfaces of the tea leaves are dried, cooling and packaging.
Example 3 health tea (extract of medicinal materials: black tea 1: 1)
The qi-regulating spleen-strengthening tea is prepared from the following raw materials in parts by weight: 2 parts of poria cocos, 2 parts of hovenia dulcis thunb, 2 parts of orange peel, 0.5 part of seville orange flower, 0.5 part of liquorice, 2 parts of Chinese date, 0.5 part of hawthorn, 0.5 part of fingered citron and 10 parts of black tea. The method comprises the following steps:
(1) taking the hawthorn, putting the hawthorn into a frying container, heating the hawthorn by slow fire until the surface is slightly yellow, taking out the hawthorn, and cooling the hawthorn.
(2) Shredding pericarpium Citri Tangerinae, heating the parching container until testa Tritici is scattered, immediately smoking, adding pericarpium Citri Tangerinae, rapidly turning, parching until surface is yellow or dark yellow, taking out, sieving to remove testa Tritici, and cooling. 0.1-0.15 part of bran is used for every 1 part of orange peel.
(3) Taking the Chinese dates, putting the Chinese dates into a frying container, heating the Chinese dates with slow fire until the surfaces of the Chinese dates are slightly yellow, taking the Chinese dates out, and cooling the Chinese dates.
(4) Taking liquorice, diluting with boiling water, adding a proper amount of refined honey, uniformly stirring, completely sealing, putting into a frying container, frying with slow fire until the surface is yellowish, taking out, and cooling. 0.25 portion of refined honey is used for every 1 portion of liquorice.
(5) Decocting the processed fructus crataegi, pericarpium Citri Tangerinae, fructus Jujubae, Glycyrrhrizae radix, Poria, semen Hoveniae, bitter Citrus immature flower and fructus Citri Sarcodactylis with 10 times of water for 2 times, mixing the decoctions for 2 times, concentrating until the relative density is 1.01-1.05(50 deg.C), adding 1-3 times of 1-8 deg.C water, standing at 1-5 deg.C for 24 hr, sucking supernatant, and concentrating until the relative density is 1.08-1.15(50 deg.C), to obtain 10 parts of Chinese medicinal extract.
(6) Putting black tea into a BY-400 water chestnut type sugar coating pan, adding the traditional Chinese medicine extract, gently stirring uniformly, and standing for about 1 h. Opening the sugar coating pan, and stirring continuously until the Chinese medicinal extract is completely absorbed. Taking out the tea leaves absorbing the traditional Chinese medicine extract, putting the tea leaves into a forced air drying oven at the temperature of 30-90 ℃ for drying until the surfaces of the tea leaves are dried, cooling and packaging. Each bag is 8 g.
Example 4 health tea (extract of medicinal materials: black tea: 3: 1)
The qi-regulating spleen-strengthening tea is prepared from the following raw materials in parts by weight: 2 parts of poria cocos, 2 parts of hovenia dulcis thunb, 2 parts of orange peel, 0.5 part of seville orange flower, 0.5 part of liquorice, 2 parts of Chinese date, 0.5 part of hawthorn, 0.5 part of fingered citron and 3.3 parts of black tea. The method comprises the following steps:
(1) taking the hawthorn, putting the hawthorn into a frying container, heating the hawthorn by slow fire until the surface is slightly yellow, taking out the hawthorn, and cooling the hawthorn.
(2) Shredding pericarpium Citri Tangerinae, heating the parching container until testa Tritici is scattered, immediately smoking, adding pericarpium Citri Tangerinae, rapidly turning, parching until surface is yellow or dark yellow, taking out, sieving to remove testa Tritici, and cooling. 0.1-0.15 part of bran is used for every 1 part of orange peel.
(3) Taking the Chinese dates, putting the Chinese dates into a frying container, heating the Chinese dates with slow fire until the surfaces of the Chinese dates are slightly yellow, taking the Chinese dates out, and cooling the Chinese dates.
(4) Taking liquorice, diluting with boiling water, adding a proper amount of refined honey, uniformly stirring, completely sealing, putting into a frying container, frying with slow fire until the surface is yellowish, taking out, and cooling. 0.25 portion of refined honey is used for every 1 portion of liquorice.
(5) Decocting the processed fructus crataegi, pericarpium Citri Tangerinae, fructus Jujubae, Glycyrrhrizae radix, Poria, semen Hoveniae, bitter Citrus immature flower and fructus Citri Sarcodactylis with 10 times of water for 2 times, mixing the decoctions for 2 times, concentrating until the relative density is 1.01-1.05(50 deg.C), adding 1-3 times of 1-8 deg.C water, standing at 1-5 deg.C for overnight, centrifuging, taking out supernatant, and concentrating until the relative density is 1.08-1.15(50 deg.C) to obtain 10 parts of Chinese medicinal extract.
(6) Putting black tea into a stainless steel pot, adding the traditional Chinese medicine extract, standing for 30 minutes, and continuously stirring. Repeating the above steps until the Chinese medicinal extract is completely absorbed. Taking out the tea leaves absorbing the traditional Chinese medicine extract, putting the tea leaves into a forced air drying oven at the temperature of 30-90 ℃ for drying until the surfaces of the tea leaves are dried, cooling and packaging.
Example 5 health tea (extract of medicinal materials: black tea 2: 1)
The qi-regulating spleen-strengthening tea is prepared from the following raw materials in parts by weight: 2 parts of poria cocos, 2 parts of hovenia dulcis thunb, 2 parts of orange peel, 0.5 part of seville orange flower, 0.5 part of liquorice, 2 parts of Chinese date, 0.5 part of hawthorn, 0.5 part of fingered citron and 5 parts of black tea. The method comprises the following steps:
(1) taking the hawthorn, putting the hawthorn into a frying container, heating the hawthorn by slow fire until the surface is slightly yellow, taking out the hawthorn, and cooling the hawthorn.
(2) Shredding pericarpium Citri Tangerinae, heating the parching container until testa Tritici is scattered, immediately smoking, adding pericarpium Citri Tangerinae, rapidly turning, parching until surface is yellow or dark yellow, taking out, sieving to remove testa Tritici, and cooling. 0.1-0.15 part of bran is used for every 1 part of orange peel.
(3) Taking the Chinese dates, putting the Chinese dates into a frying container, heating the Chinese dates with slow fire until the surfaces of the Chinese dates are slightly yellow, taking the Chinese dates out, and cooling the Chinese dates.
(4) Taking liquorice, diluting with boiling water, adding a proper amount of refined honey, uniformly stirring, completely sealing, putting into a frying container, frying with slow fire until the surface is yellowish, taking out, and cooling. 0.25 portion of refined honey is used for every 1 portion of liquorice.
(5) Decocting the processed fructus crataegi, pericarpium Citri Tangerinae, fructus Jujubae, Glycyrrhrizae radix, Poria, semen Hoveniae, bitter Citrus immature flower and fructus Citri Sarcodactylis with 10 times of water for 2 times, mixing the decoctions for 2 times, concentrating until the relative density is 1.01-1.05(50 deg.C), adding 1-3 times of 1-8 deg.C water, standing at 1-5 deg.C for overnight, centrifuging, taking out supernatant, and concentrating until the relative density is 1.08-1.15(50 deg.C) to obtain 10 parts of Chinese medicinal extract.
(6) Putting black tea into a stainless steel pot, adding the traditional Chinese medicine extract, standing for 30 minutes, and continuously stirring. Repeating the above steps until the Chinese medicinal extract is completely absorbed. Taking out the tea leaves absorbing the traditional Chinese medicine extract, putting the tea leaves into a forced air drying oven at the temperature of 30-90 ℃ for drying until the surfaces of the tea leaves are dried, cooling and packaging.
Comparative example 1: pure medicinal material extract
The feed is prepared from the following raw materials in parts by weight: 2 parts of poria cocos, 2 parts of hovenia dulcis thunb, 2 parts of orange peel, 0.5 part of seville orange flower, 0.5 part of liquorice, 2 parts of Chinese date, 0.5 part of hawthorn and 0.5 part of fingered citron. The method comprises the following steps:
(1) taking the hawthorn, putting the hawthorn into a frying container, heating the hawthorn by slow fire until the surface is slightly yellow, taking out the hawthorn, and cooling the hawthorn.
(2) Shredding pericarpium Citri Tangerinae, heating the parching container until testa Tritici is scattered, immediately smoking, adding pericarpium Citri Tangerinae, rapidly turning, parching until surface is yellow or dark yellow, taking out, sieving to remove testa Tritici, and cooling. 0.1-0.15 part of bran is used for every 1 part of orange peel.
(3) Taking the Chinese dates, putting the Chinese dates into a frying container, heating the Chinese dates with slow fire until the surfaces of the Chinese dates are slightly yellow, taking the Chinese dates out, and cooling the Chinese dates.
(4) Taking liquorice, diluting with boiling water, adding a proper amount of refined honey, uniformly stirring, completely sealing, putting into a frying container, frying with slow fire until the surface is yellowish, taking out, and cooling. 0.25 portion of refined honey is used for every 1 portion of liquorice.
(5) Decocting the processed fructus crataegi, pericarpium Citri Tangerinae, fructus Jujubae, Glycyrrhrizae radix, Poria, semen Hoveniae, bitter Citrus immature flower and fructus Citri Sarcodactylis with 10 times of water for 2 times, mixing the decoctions for 2 times, concentrating until the relative density is 1.01-1.05(50 deg.C), adding 1-3 times of 1-8 deg.C water, standing at 1-5 deg.C for overnight, centrifuging, taking out supernatant, and concentrating until the relative density is 1.08-1.15(50 deg.C) to obtain extract.
Comparative example 2: health tea without semen Hoveniae and fructus Citri Sarcodactylis
The feed is prepared from the following raw materials in parts by weight: 2g of poria cocos, 2g of orange peel, 0.5g of seville orange flower, 0.5g of liquorice, 2g of Chinese date, 0.5g of hawthorn and 5g of black tea. The method comprises the following steps:
(1) taking the hawthorn, putting the hawthorn into a frying container, heating the hawthorn by slow fire until the surface is slightly yellow, taking out the hawthorn, and cooling the hawthorn.
(2) Shredding pericarpium Citri Tangerinae, heating the parching container until testa Tritici is scattered, immediately smoking, adding pericarpium Citri Tangerinae, rapidly turning, parching until surface is yellow or dark yellow, taking out, sieving to remove testa Tritici, and cooling. 0.1-0.15 part of bran is used for every 1 part of orange peel.
(3) Taking the Chinese dates, putting the Chinese dates into a frying container, heating the Chinese dates with slow fire until the surfaces of the Chinese dates are slightly yellow, taking the Chinese dates out, and cooling the Chinese dates.
(4) Taking liquorice, diluting with boiling water, adding a proper amount of refined honey, uniformly stirring, completely sealing, putting into a frying container, frying with slow fire until the surface is yellowish, taking out, and cooling. 0.25 portion of refined honey is used for every 1 portion of liquorice.
(5) Decocting the processed fructus crataegi, pericarpium Citri Tangerinae, fructus Jujubae, Glycyrrhrizae radix, Poria and bitter orange flower with 10 times of water for 2 times, mixing decoctions for 2 times, concentrating until the relative density is 1.01-1.05(50 deg.C), adding 1-3 times of 1-8 deg.C water, standing at 1-5 deg.C overnight, centrifuging, taking out supernatant, concentrating until the relative density is 1.08-1.15(50 deg.C), to obtain extract, mixing the extract with black tea, drying, and packaging.
Comparative example 3: health tea containing Poria and fructus Jujubae
The qi-regulating spleen-strengthening tea is prepared from the following raw materials in parts by weight: 2g of hovenia dulcis thunb, 2g of orange peel, 0.5g of seville orange flower, 0.5g of liquorice, 0.5g of hawthorn, 0.5g of fingered citron and 5g of black tea. The method comprises the following steps:
(1) taking the hawthorn, putting the hawthorn into a frying container, heating the hawthorn by slow fire until the surface is slightly yellow, taking out the hawthorn, and cooling the hawthorn.
(2) Shredding pericarpium Citri Tangerinae, heating the parching container until testa Tritici is scattered, immediately smoking, adding pericarpium Citri Tangerinae, rapidly turning, parching until surface is yellow or dark yellow, taking out, sieving to remove testa Tritici, and cooling. 0.1-0.15 part of bran is used for every 1 part of orange peel.
(3) Taking liquorice, diluting with boiling water, adding a proper amount of refined honey, uniformly stirring, completely sealing, putting into a frying container, frying with slow fire until the surface is yellowish, taking out, and cooling. 0.25 portion of refined honey is used for every 1 portion of liquorice.
(4) Decocting the processed fructus crataegi, pericarpium Citri Tangerinae, Glycyrrhrizae radix, semen Hoveniae, bitter Citrus immature flower and fructus Citri Sarcodactylis with 10 times of water for 2 times, mixing the decoctions for 2 times, concentrating until the relative density is 1.01-1.05(50 deg.C), adding 1-3 times of 1-8 deg.C water, standing at 1-5 deg.C overnight, centrifuging, taking out supernatant, concentrating until the relative density is 1.08-1.15(50 deg.C), to obtain extract, mixing the extract with black tea, drying, and packaging.
Pharmacodynamic test example 1,
Purpose of experiment
The influence of the medicinal materials, the tea leaves and the qi-regulating and spleen-strengthening tea on the gastric emptying and intestinal propulsion movement of the mice is observed.
Experimental methods
Examples 1, 2, 3, 4, 5, comparative examples 1, 2, 3.
The preparation method of each medicinal material sample comprises the following steps: respectively adding 10 times of water into poria cocos, hovenia dulcis thumb, orange peel, Chinese date, liquorice, hawthorn, fingered citron and seville orange flower medicinal materials (the orange peel, the Chinese date, the liquorice and the hawthorn are processed by the processing method in the embodiment 1), boiling for 2 times, merging and concentrating 2 times of decoction until the relative density is 1.01-1.25(50 ℃), adding 1-3 times of 1-8 ℃ water, standing overnight at 1-5 ℃, centrifuging, taking out supernatant liquid, and concentrating to obtain poria cocos extract, orange peel extract, liquorice extract, hawthorn extract, fingered citron extract and seville orange flower extract. The tea is prepared by infusing with 5 times of boiling water.
Domperidone is taken as a positive control group (3mg/Kg), distilled water is taken as a normal control group, atropine sulfate is taken as a molding group, examples 1-5 groups (2g crude drug/Kg), comparison 1-3 groups (2g crude drug/Kg), a poria cocos experiment group (2g crude drug/Kg), an orange peel experiment group (2g crude drug/Kg), a liquorice experiment group (2g crude drug/Kg), a hawthorn experiment group (2g crude drug/Kg), a fingered citron experiment group (2g crude drug/Kg), a seville orange flower experiment group (2g crude drug/Kg), and the stomach is continuously infused for 2 weeks.
The method comprises the following steps of uniformly dividing 200 Kunming mice into 20 groups according to weight, wherein each group comprises 10 mice, each mouse is administrated with 2g of crude drug/kg of weight, the liquid medicine is diluted to 0.2g/m L, each mouse is administrated with 0.1mL/10g of weight, the normal group is administrated with equal volume of distilled water, the model group is administrated with equal volume of distilled water, the domperidone group is prepared into 1mg/mL of concentration, each mouse is administrated with 0.1mL/10g of weight, the administration is fixed at the same time every day, and the administration lasts for 2 weeks. At 20min after administration, mice in each group were injected subcutaneously with atropine sulfate (2mg/kg) except for the normal control group. The day before the experiment was fasted for 18 hours, 2 hours after the last administration, the pigments, 0.3ml each, were administered, and after 15 minutes the animals were sacrificed by cervical dislocation and the entire gastrointestinal tract was opened for measurement.
The pigment is a fluid preparation of dextran blue and Arabic gum prepared from 2% dextran blue and 7.5% Arabic gum by distilled water, and the residual ratio in stomach and the distance ratio from pyloric sphincter to pigment foremost and to cecum are observed.
The stomach was removed from the pyloric sphincter, the residual pigment was fully dissolved in 2ml of distilled water, centrifuged at 3000rpm for 15min, the supernatant was collected at λ 620nm of "721 spectrophotometer", and the absorbance was set to zero by a distilled water tube to obtain the residual ratio of the pigment in the stomach, and the mean value of each group was determined. And measuring the distance from the pyloric sphincter to the forefront of pigment and the distance from the pyloric sphincter to the cecum respectively, taking the ratio of the pyloric sphincter to the pigment to be the small intestine propulsion ratio, and calculating the average value of each group. The results of the experiment are shown in table 1.
TABLE 1 comparison of gastric emptying and Small intestine Pushing ratio parameters for various groups of animals
Note: in comparison with the normal group,*P<0.05,**P<0.01; in comparison with the set of models,#P<0.05,##P<0.01 conclusion of the experiment:
the gastric residual rate of the model group is obviously increased compared with the normal group (P <0.01), the gastric residual rate is obviously reduced after the positive drug is given, and the difference has very significant meaning (P <0.01) compared with the model group and has no significant difference compared with the normal group. The residue rate of the honey-fried licorice root group is increased compared with that of the model group, and the significant difference is achieved (P is less than 0.05). A significant increase compared to the normal group (P < 0.01); the gastric residue rates of the tuckahoe, the hovenia dulcis thunb, the bran-fried orange peel, the fried Chinese date, the finger citron, the seville orange flower group and the tea mouse are reduced compared with the model group, but the difference is not statistically significant (P is more than 0.05), and is obviously increased compared with the normal group (P is less than 0.01). The gastric residual rate of the stir-fried hawthorn group is obviously reduced compared with that of the model group (P < 0.05). A significant increase compared to the normal group (P < 0.01). The liquorice has obvious inhibition effect on the gastric emptying and small intestine propulsion functions of the mice, other traditional Chinese medicines, tea leaves and the contrast groups 1-3 have certain promotion effect on the gastric emptying functions of the mice, but the atropine sulfate can not be completely antagonized to inhibit the gastric emptying functions of the mice, and the gastric emptying functions can not be recovered to the level of the normal groups.
The stomach residue rate of the groups 1 to 5 of the tea for regulating qi and strengthening spleen is obviously reduced compared with that of the model group, the difference has extremely significant significance (P <0.01), and the difference is not obvious (P >0.05) compared with that of the normal group; the invention shows that the qi-regulating and spleen-strengthening tea can obviously enhance the gastric emptying function, can completely antagonize the gastric emptying function of mice inhibited by atropine sulfate, and can restore the gastric emptying function to a normal level. The tea for regulating qi and strengthening spleen in example 5 has the smallest stomach residue ratio and the strongest effect of promoting gastric emptying.
The intestinal propulsion rate of the model group is obviously reduced compared with that of the normal group (P <0.01), and the intestinal propulsion rate of mice of other medicinal materials such as poria cocos, hovenia dulcis thunb, bran-fried orange peel, fried Chinese date, fingered citron, seville orange flower, fried hawthorn and tea group and the control group is obviously increased compared with the model group (P <0.05) and is obviously reduced compared with the normal group (P <0.05) except that the honey-fried licorice root group reduces the intestinal propulsion rate of the mice. The liquorice has obvious inhibition effect on the mouse small intestine propulsion function, other traditional Chinese medicines, tea and contrast have certain effects on the mouse gastric emptying and small intestine propulsion function, but the atropine sulfate can not be completely antagonized to inhibit the mouse small intestine propulsion function, and the small intestine propulsion function can not be recovered to the normal group level. The qi regulating and spleen strengthening tea can obviously increase the intestinal propulsion rate of mice in each embodiment group 1-5, has a very significant meaning (P <0.01) compared with a model group, and has no significant difference (P >0.05) compared with a normal group. The effect of regulating qi and strengthening spleen is proved that the tea can obviously enhance the intestinal propulsion function, can completely antagonize the intestinal propulsion function of mice inhibited by atropine sulfate, and can restore the intestinal propulsion function to a normal level. The qi-regulating and spleen-tonifying tea in example 5 has the largest small intestine propulsion ratio and the strongest intestine propulsion promoting effect.
Therefore, the qi-regulating and spleen-strengthening tea prepared according to the traditional Chinese medicine theory has the advantages that all medicinal materials can play a synergistic effect, the effects of promoting gastric emptying and promoting intestinal propulsion are obviously improved compared with all medicinal material groups, the raw material composition, the extract and the tea proportion can play a better effect, and the functions of gastric emptying and intestinal propulsion of mice with the inhibited functions of gastric emptying and intestinal propulsion can be recovered to normal level. The qi regulating and spleen strengthening tea has the functions of regulating qi, tonifying qi, strengthening spleen and nourishing stomach, and particularly has exact efficacy on functional dyspepsia. Wherein the raw materials comprise: 2 parts of poria cocos, 2 parts of orange peel, 0.5 part of seville orange flower, 0.5 part of liquorice, 2 parts of Chinese date, 0.5 part of hawthorn, 0.5 part of fingered citron, 5 parts of black tea and a traditional Chinese medicine extract: the health tea prepared when the tea is 2:1 has the best effect. Animal experiments show that the health tea can achieve the equivalent gastric emptying and intestinal propulsion functions of domperidone, has the same medicinal effect, does not have the side effect of chemical domperidone, has good taste and can be taken for a long time.
Clinical trial example 2:
experimental purpose and design method
The effectiveness of the qi regulating and spleen strengthening tea for treating functional dyspepsia is evaluated by adopting random and cross-control clinical research design.
Evaluating the gastrointestinal functions of the persons participating in the trial by a tabulating and scoring mode, wherein the scoring is divided into two times of scoring respectively, recording a base line for the first time, recording the scoring condition again when the second trial is finished, and calculating the scoring change condition by using a nimodipine method as a curative effect evaluation method.
Criteria for selection of medical records
The functional dyspepsia diagnosis standard is implemented according to the regulations of the guidelines (survey papers) for clinical research on new Chinese medicines for functional dyspepsia issued by the drug evaluation center of the State food and drug administration. The contents are as follows:
and (3) master certificate: firstly, the patient feels full and uncomfortable after meals; early satiety; ③ epigastric pain; the burning sensation of the middle and upper abdomen.
Secondary verification: firstly, belching and acid regurgitation; ② nausea and vomiting; ③ lack of strength; fourthly, inappetence; dry mouth with bitter taste.
The chief complaints include 1 or more of them, and the occurrence of symptoms for at least 3 months is the diagnostic criterion. Conventional examinations, including gastroscopies, have found no evidence of organic, systemic or metabolic disease that could explain the above symptoms.
The scoring criteria are as follows:
TABLE 2 hierarchical quantitative score standard table for major syndrome and minor syndrome
Inclusion criteria
[1] The age is 18 years old or older, with unlimited nature.
[2] The traditional Chinese medicine syndrome differentiation diagnosis has functional dyspepsia symptoms, and accords with established diagnosis standards (major syndrome and minor syndrome).
[3] The whole experimental process is understood and voluntarily participated.
Medical record exclusion criteria
[1] Pregnant, ready-to-pregnancy or lactating women.
[2] Allergic to the Chinese medicinal materials.
[3] Patients in other clinical trials were enrolled during the last 3 months.
Treatment regimens
Name and Specification of clinical samples
(1) The qi regulating and spleen strengthening tea (sample in example 5) is brewed with 6.8g of hot water (300-.
(2) Appetizing and spleen tonifying pills, each 10 pills are taken with warm water onceIt is administered 2 times a day.
Clinical sample dispensing and dispensing
The test subjects took the qi-regulating and spleen-invigorating tea and the appetite-promoting and spleen-invigorating pill respectively according to random distribution. Fill in record baseline information of 'health tea tester condition record table'. If the symptoms are improved in the trial, the 'observation diary' is filled in to record the symptom improvement time and the current score.
The amount of the tea for regulating qi and strengthening spleen and the pills for stimulating appetite and strengthening spleen is 2 weeks (14 days), and the effectiveness test of the curative effect of the tea is carried out.
Test results
The recruited population is as follows: the people who have functional dyspepsia, postprandial discomfort, early satiety (feel full after eating a little), gastrectasia, inappetence, dyspepsia and other symptoms (except pregnant women, lactating women and minors) recruit 42 people in total, 10 people fall off, and the effective statistical population is 32 people.
TABLE 3 comparison of general data of two groups of subjects
TABLE 4 comparison of symptom scores of two groups of patients before drug administration
TABLE 5 distribution of symptoms when test subjects were enrolled
The syndrome curative effect index is calculated by adopting a nimodipine method, and the calculation formula is as follows:
percent reduction in syndrome score is (pre-treatment score-post-treatment score)/pre-treatment score × 100%.
And (3) healing: a reduction of greater than or equal to 90%; the effect is shown: greater than or equal to 70% and less than 90%; the method has the following advantages: greater than or equal to 30% and less than 70%; and (4) invalidation: the reduction is less than 30%.
After 14 days of trial, the results were as follows:
TABLE 6 effective rate statistics of symptoms (Qi regulating and spleen invigorating tea)
TABLE 7 effective rate statistics of symptoms (appetizing and spleen-invigorating pill)
From the results shown in fig. 1, it can be seen that the effective rate of the qi-regulating and spleen-invigorating tea for treating the functional dyspepsia symptoms (postprandial fullness and discomfort, early satiety, epigastric pain, and burning sensation of the upper middle abdomen) is higher than that of the appetizing and spleen-invigorating pill, and the effective rate of the qi-regulating and spleen-invigorating tea for treating the symptoms except hypodynamia is higher than that of the appetizing and spleen-invigorating pill. The qi-regulating spleen-strengthening tea has a remarkable treatment effect on functional dyspepsia.
Claims (10)
1. A health tea with qi regulating and spleen invigorating effects is characterized by comprising medicinal and edible medicinal material extracts and tea leaves according to a weight ratio of 1: 10-10: 1, the components of the composition are mixed,
wherein the tea is 1-50 parts, and the medicinal material extract is prepared from the following raw materials in parts by weight: 1-5 parts of poria cocos, 1-4 parts of hovenia dulcis thunb, 1-4 parts of orange peel, 0.1-1 part of seville orange flower, 0.1-1 part of liquorice, 1-4 parts of Chinese date, 0.1-1 part of hawthorn and 0.1-1 part of fingered citron.
2. The health tea as claimed in claim 1, wherein the tea is prepared from the extract of medicinal and edible medicinal materials and tea according to the weight ratio of 1: 5-5: 1, the components of the composition are mixed,
wherein the tea is 3-30 parts, and the medicinal material extract is prepared from the following raw materials in parts by weight: 2-4 parts of poria cocos, 2-3 parts of hovenia dulcis thunb, 2-3 parts of orange peel, 0.5-1 part of seville orange flower, 0.5-1 part of liquorice, 0.5-2 parts of Chinese date, 0.5-1 part of hawthorn and 0.5-1 part of fingered citron.
3. The health tea as claimed in claim 1, wherein the weight ratio of the extract of medicinal and edible medicinal materials to the oolong tea is 1: 2, the components are mixed to form a mixture,
the oolong tea is 30 parts, and the medicinal material extract is prepared from the following raw materials in parts by weight: 3 parts of poria cocos, 4 parts of hovenia dulcis thunb, 3 parts of orange peel, 0.2 part of seville orange flower, 0.3 part of liquorice, 3 parts of Chinese date, 0.5 part of hawthorn and 0.5 part of fingered citron.
4. The health tea as claimed in claim 1, wherein the tea is prepared from the extract of medicinal and edible medicinal materials and black tea in a weight ratio of 2:1, the components of the composition are mixed,
wherein the black tea is 5 parts, and the medicinal material extract is prepared from the following raw materials in parts by weight: 2 parts of poria cocos, 2 parts of hovenia dulcis thunb, 2 parts of orange peel, 0.5 part of seville orange flower, 0.5 part of liquorice, 2 parts of Chinese date, 0.5 part of hawthorn and 0.5 part of fingered citron.
5. The method for preparing a health tea according to claim 1, comprising the steps of:
parching pericarpium Citri Tangerinae with bran, parching Glycyrrhrizae radix with Mel, parching fructus Jujubae, parching fructus crataegi, decocting pericarpium Citri Tangerinae, Glycyrrhrizae radix, fructus Jujubae, fructus crataegi and Poria, semen Hoveniae, bitter orange flower and fructus Citri Sarcodactylis in water, concentrating, precipitating with water, concentrating to obtain extract, mixing with folium Camelliae sinensis, adhering the extract to folium Camelliae sinensis, and drying.
6. The method of claim 5, comprising the steps of:
(1) taking hawthorn, putting the hawthorn into a frying container, heating the hawthorn by slow fire until the surface of the hawthorn is slightly yellow, taking out the hawthorn, and cooling the hawthorn;
(2) shredding pericarpium Citri Tangerinae, heating the stir-fried container, adding pericarpium Citri Tangerinae, sieving to remove testa Tritici, and cooling;
(3) taking the Chinese dates, putting the Chinese dates into a frying container, heating the Chinese dates with slow fire until the surfaces of the Chinese dates are slightly yellow, taking the Chinese dates out, and cooling the Chinese dates;
(4) taking liquorice, diluting with boiling water, adding a proper amount of refined honey, uniformly stirring, stewing thoroughly, putting into a frying container, frying with slow fire until the surface is yellowish, taking out, and cooling;
(5) decocting the processed fructus crataegi, pericarpium Citri Tangerinae, fructus Jujubae, Glycyrrhrizae radix, Poria, semen Hoveniae, bitter Citrus aurantium and fructus Citri Sarcodactylis with 8-12 times of water for 1-3 times, mixing decoctions, concentrating to relative density of 1.01-1.25(50 deg.C), adding 1-3 times of water, standing overnight, centrifuging, collecting supernatant, concentrating to relative density of 1.05-1.35(50 deg.C), to obtain Chinese medicinal extract;
(6) putting tea into a sugar coating pan, adding the Chinese medicinal extract, gently stirring, standing for about 0.2-2 hr, opening the sugar coating pan, and stirring continuously until the Chinese medicinal extract is completely absorbed; or placing tea into stainless steel pot, adding Chinese medicinal extract, standing for 0.1-10 hr, stirring, repeating above steps until the Chinese medicinal extract is completely absorbed, taking out tea with adsorbed Chinese medicinal extract, drying in 30-90 deg.C forced air drying oven until surface is dried, cooling, and packaging.
7. The method of claim 5, comprising the steps of:
(1) taking hawthorn, putting the hawthorn into a frying container, heating the hawthorn by slow fire until the surface of the hawthorn is slightly yellow, taking out the hawthorn, and cooling the hawthorn;
(2) taking and shredding orange peel, heating a frying container until bran is scattered and the orange peel is smoked immediately, immediately adding the orange peel, rapidly turning over, taking out when the surface is yellow or dark yellow, sieving to remove the bran, and cooling, wherein 0.1-0.15 part of the bran is used for every 1 part of the orange peel;
(3) taking the Chinese dates, putting the Chinese dates into a frying container, heating the Chinese dates with slow fire until the surfaces of the Chinese dates are slightly yellow, taking the Chinese dates out, and cooling the Chinese dates;
(4) taking liquorice, diluting with boiling water, adding proper amount of refined honey, uniformly stirring, completely sealing, putting into a frying container, frying with slow fire until the surface becomes yellowish, taking out, cooling, and using 0.25 part of refined honey for every 1 part of liquorice;
(5) decocting the processed fructus crataegi, pericarpium Citri Tangerinae, fructus Jujubae, Glycyrrhrizae radix, Poria, semen Hoveniae, bitter Citrus aurantium and fructus Citri Sarcodactylis with 10 times of water for 2 times, mixing the decoctions for 2 times, concentrating to relative density of 1.01-1.05(50 deg.C), adding 1-3 times of 1-8 deg.C water, standing at 1-5 deg.C for overnight, centrifuging, collecting supernatant, and concentrating to relative density of 1.08-1.15(50 deg.C) to obtain Chinese medicinal extract;
(6) putting tea into a sugar coating pan, adding the Chinese medicinal extract, gently stirring, standing for about 0.2-2 hr, opening the sugar coating pan, and stirring continuously until the Chinese medicinal extract is completely absorbed; or placing tea into stainless steel pot, adding Chinese medicinal extract, standing for 0.1-10 hr, stirring, repeating above steps until the Chinese medicinal extract is completely absorbed, taking out tea with adsorbed Chinese medicinal extract, drying in 30-90 deg.C forced air drying oven until surface is dried, cooling, and packaging.
8. The health tea as claimed in claim 1, wherein the tea leaves are selected from green tea, black tea, oolong tea, dark tea, yellow tea, white tea, scented tea.
9. The use of the health tea of claim 1 in the preparation of a medicament for regulating the flow of qi to invigorate the spleen.
10. The use of the health tea of claim 1 in the manufacture of a medicament for invigorating spleen and stomach, protecting gastric mucosa, treating functional dyspepsia, and improving appetite in a patient.
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Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101041023A (en) * | 2007-04-24 | 2007-09-26 | 西安一枝刘制药有限公司 | Chinese traditional compound good for spleen and for improving appetite and food-digesting and the preparing method |
CN102552493A (en) * | 2012-02-02 | 2012-07-11 | 贵州益佰制药股份有限公司 | Anti-inebriation drunk-preventing composition and preparation method thereof |
CN102948549A (en) * | 2011-08-30 | 2013-03-06 | 天津尖峰弗兰德医药科技发展有限公司 | Healthy tea with effects of tonifying spleen and promoting appetite and preparation method of healthy tea |
CN104115959A (en) * | 2013-04-26 | 2014-10-29 | 南京瑞真堂医药保健有限公司 | Health-care tea beverage |
CN104189264A (en) * | 2014-09-12 | 2014-12-10 | 兰州古驰生物科技有限公司 | Chinese medicine preparation with functions of harmonizing stomach and dispelling alcoholic effect |
CN105943964A (en) * | 2016-06-24 | 2016-09-21 | 湖北丽生堂生物科技有限公司 | Drink with digestion promoting function and preparation method thereof |
CN106615333A (en) * | 2015-08-10 | 2017-05-10 | 哈尔滨灵丹鸿运茶品有限公司 | Fortunella japonica (thunb.) swingle spleen strengthening and qi regulating tea and preparation method thereof |
CN108785566A (en) * | 2018-08-01 | 2018-11-13 | 陕西红顶名医堂药业有限公司 | For treating damp heat in the spleen and the stomach Chinese medicine composition and preparation method thereof |
-
2020
- 2020-05-28 CN CN202010464407.5A patent/CN111670977B/en active Active
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101041023A (en) * | 2007-04-24 | 2007-09-26 | 西安一枝刘制药有限公司 | Chinese traditional compound good for spleen and for improving appetite and food-digesting and the preparing method |
CN102948549A (en) * | 2011-08-30 | 2013-03-06 | 天津尖峰弗兰德医药科技发展有限公司 | Healthy tea with effects of tonifying spleen and promoting appetite and preparation method of healthy tea |
CN102552493A (en) * | 2012-02-02 | 2012-07-11 | 贵州益佰制药股份有限公司 | Anti-inebriation drunk-preventing composition and preparation method thereof |
CN104115959A (en) * | 2013-04-26 | 2014-10-29 | 南京瑞真堂医药保健有限公司 | Health-care tea beverage |
CN104189264A (en) * | 2014-09-12 | 2014-12-10 | 兰州古驰生物科技有限公司 | Chinese medicine preparation with functions of harmonizing stomach and dispelling alcoholic effect |
CN106615333A (en) * | 2015-08-10 | 2017-05-10 | 哈尔滨灵丹鸿运茶品有限公司 | Fortunella japonica (thunb.) swingle spleen strengthening and qi regulating tea and preparation method thereof |
CN105943964A (en) * | 2016-06-24 | 2016-09-21 | 湖北丽生堂生物科技有限公司 | Drink with digestion promoting function and preparation method thereof |
CN108785566A (en) * | 2018-08-01 | 2018-11-13 | 陕西红顶名医堂药业有限公司 | For treating damp heat in the spleen and the stomach Chinese medicine composition and preparation method thereof |
Non-Patent Citations (1)
Title |
---|
包国林等: "胃长康胶囊对胃肠道功能的影响", 《中药材》 * |
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