CN111655121B - 微血管阻塞(mvo)和心肌梗死的冠状动脉内表征 - Google Patents

微血管阻塞(mvo)和心肌梗死的冠状动脉内表征 Download PDF

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Publication number
CN111655121B
CN111655121B CN201880070198.7A CN201880070198A CN111655121B CN 111655121 B CN111655121 B CN 111655121B CN 201880070198 A CN201880070198 A CN 201880070198A CN 111655121 B CN111655121 B CN 111655121B
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mvo
pressure
blood
subject matter
infusion
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Chinese (zh)
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CN111655121A (zh
Inventor
约恩·黑尔格·赫姆
罗伯特·S·施瓦茨
马丁·T·罗思曼
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Corflow Therapeutics AG
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Corflow Therapeutics AG
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/02007—Evaluating blood vessel condition, e.g. elasticity, compliance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/0215—Measuring pressure in heart or blood vessels by means inserted into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/0215—Measuring pressure in heart or blood vessels by means inserted into the body
    • A61B5/02152—Measuring pressure in heart or blood vessels by means inserted into the body specially adapted for venous pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/026—Measuring blood flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4848—Monitoring or testing the effects of treatment, e.g. of medication
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6852—Catheters
    • A61B5/6853—Catheters with a balloon
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G16H20/17—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Physiology (AREA)
  • Vascular Medicine (AREA)
  • Primary Health Care (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Databases & Information Systems (AREA)
  • General Business, Economics & Management (AREA)
  • Business, Economics & Management (AREA)
  • Data Mining & Analysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Surgical Instruments (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
CN201880070198.7A 2017-09-19 2018-09-19 微血管阻塞(mvo)和心肌梗死的冠状动脉内表征 Active CN111655121B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762560545P 2017-09-19 2017-09-19
US62/560,545 2017-09-19
PCT/US2018/051760 WO2019060421A1 (en) 2017-09-19 2018-09-19 INTRACORONARY MICROVASCULAR OBSTRUCTION CHARACTERIZATION (MVO) AND MYOCARDIAL INFARCTION

Publications (2)

Publication Number Publication Date
CN111655121A CN111655121A (zh) 2020-09-11
CN111655121B true CN111655121B (zh) 2024-05-24

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Country Status (7)

Country Link
US (1) US11412936B2 (enExample)
EP (1) EP3684247A1 (enExample)
JP (1) JP7249672B2 (enExample)
CN (1) CN111655121B (enExample)
AU (1) AU2018336787B2 (enExample)
CA (1) CA3076035A1 (enExample)
WO (1) WO2019060421A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11786140B2 (en) 2019-08-21 2023-10-17 Corflow Therapeutics Ag Controlled-flow infusion catheter and method
AU2017205404B2 (en) 2016-01-04 2020-10-08 Corflow Therapeutics Ag System and methods for treating MVO
US11724030B2 (en) 2018-09-21 2023-08-15 Corflow Therapeutics Ag Method and apparatus for diagnosis and treatment of microvascular dysfunction
CA3076035A1 (en) 2017-09-19 2019-03-28 Corflow Therapeutics Ag Intracoronary characterization of microvascular obstruction (mvo) and myocardial infarction
ES2992050T3 (es) 2018-03-09 2024-12-05 Corflow Therapeutics Ag Sistema para diagnosticar y tratar obstrucciones microvasculares
WO2019232452A1 (en) 2018-05-31 2019-12-05 Bernard Andre Microfluidic coronary circulatory model
AU2021274173A1 (en) * 2020-05-22 2022-12-22 Corflow Therapeutics Ag Controlled flow infusion microvascular dysfunction diagnostic and therapy
AU2022206116A1 (en) * 2021-01-11 2023-07-20 Corflow Therapeutics Ag Apparatus and method for determining and/or treating microvascular obstruction
WO2025160126A1 (en) * 2024-01-22 2025-07-31 The Trustees Of Indiana University Method and system for radiation-free assessment of coronary and skeletal muscle microvascular function using in-situ administration of vasoactive agents
CN117976155B (zh) * 2024-04-01 2024-07-26 杭州脉流科技有限公司 基于造影剂示踪曲线获得冠脉功能学参数的方法、计算机设备

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102596010A (zh) * 2009-08-10 2012-07-18 P2科学有限公司 用于诊断狭窄和其他血流受限之病症的utp
CN105636512A (zh) * 2013-08-14 2016-06-01 南洋理工大学 用于评估血管重建的系统和方法
CN105848573A (zh) * 2013-10-25 2016-08-10 波士顿科学国际有限公司 利用光学传感来确定血流量的导管系统和方法

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4689041A (en) 1984-01-20 1987-08-25 Eliot Corday Retrograde delivery of pharmacologic and diagnostic agents via venous circulation
US5439446A (en) 1994-06-30 1995-08-08 Boston Scientific Corporation Stent and therapeutic delivery system
US20050245894A1 (en) 1996-05-20 2005-11-03 Medtronic Vascular, Inc. Methods and apparatuses for drug delivery to an intravascular occlusion
US20010041862A1 (en) 1997-09-02 2001-11-15 Morton G. Glickman Novel apparatus and method of treating a tumor in the extremity of a patient
EP0917886B1 (en) 1997-10-23 2003-10-01 Schneider (Europe) GmbH Seal for catheter assembly with dilation and occlusion balloon
US20040260333A1 (en) 1997-11-12 2004-12-23 Dubrul William R. Medical device and method
US6622367B1 (en) 1998-02-03 2003-09-23 Salient Interventional Systems, Inc. Intravascular device and method of manufacture and use
US6295990B1 (en) 1998-02-03 2001-10-02 Salient Interventional Systems, Inc. Methods and systems for treating ischemia
US6423032B2 (en) 1998-03-13 2002-07-23 Arteria Medical Science, Inc. Apparatus and methods for reducing embolization during treatment of carotid artery disease
US6488671B1 (en) 1999-10-22 2002-12-03 Corazon Technologies, Inc. Methods for enhancing fluid flow through an obstructed vascular site, and systems and kits for use in practicing the same
US6485500B1 (en) 2000-03-21 2002-11-26 Advanced Cardiovascular Systems, Inc. Emboli protection system
US6616597B2 (en) 2000-12-12 2003-09-09 Datascope Investment Corp. Intra-aortic balloon catheter having a dual sensor pressure sensing system
US7722596B2 (en) 2004-02-26 2010-05-25 Osprey Medical, Inc. Regional cardiac tissue treatment
US7955371B2 (en) 2004-05-12 2011-06-07 Medtronic Vascular, Inc. System and method for stent deployment and infusion of a therapeutic agent into tissue adjacent to the stent ends
IES20040803A2 (en) 2004-12-01 2006-06-14 Medtronic Vascular Connaught Drug delivery device
US7837650B1 (en) 2004-12-30 2010-11-23 Advanced Cardiovascular Systems, Inc. Method and apparatus to prevent reperfusion injury
WO2007061530A1 (en) 2005-10-14 2007-05-31 Cytori Therapeutics, Inc. Cell delivery catheters with distal tip high fidelity sensors
EP2073884B1 (en) 2006-08-02 2018-10-10 Osprey Medical Inc. Microvascular obstruction detection and therapy
CN201058169Y (zh) 2007-05-24 2008-05-14 席刚明 一种同轴球囊溶栓导管
US8216209B2 (en) 2007-05-31 2012-07-10 Abbott Cardiovascular Systems Inc. Method and apparatus for delivering an agent to a kidney
WO2009067212A1 (en) 2007-11-19 2009-05-28 Mallinckrodt Inc. Power injector having patency check with pressure monitoring
JP5147004B2 (ja) 2008-03-27 2013-02-20 国立大学法人鳥取大学 生体内温熱療法及び閉塞下動注化学療法を併用した新規治療方法に用いるバルーンカテーテル
EP3093039A1 (en) 2008-11-03 2016-11-16 Advanced Catheter Therapies, Inc. Occlusion perfusion catheter
JP5676564B2 (ja) 2009-03-31 2015-02-25 セント ジュード メディカル システムズ エービー センサ・ガイド・ワイヤ
US8706209B2 (en) 2010-02-05 2014-04-22 3Dt Holdings, Llc Devices, systems, and methods for measuring parallel tissue conductance, luminal cross-sectional areas, fluid velocity, and/or determining plaque vulnerability using temperature
US8821438B2 (en) 2010-04-30 2014-09-02 Abbott Cardiovascular Systems, Inc. Catheter system having a fluid circuit
US8708996B2 (en) 2010-04-30 2014-04-29 Abbott Cardiovascular Systems, Inc. Methods and device for synergistic mitigation of reperfusion injury after an ischemic event
US8540669B2 (en) 2010-04-30 2013-09-24 Abbott Cardiovascular Systems Inc. Catheter system providing step reduction for postconditioning
WO2011161212A1 (en) * 2010-06-23 2011-12-29 P2-Science Aps Combined flow directed intraarterial microcatheter for the infusion of hyperemic agent and concomitant pressure measurements for diagnostic purposes
US20120157913A1 (en) 2010-12-16 2012-06-21 Atherolysis Medical, Inc. Catheter apparatus and method for atherolysis
US9533124B2 (en) 2011-04-14 2017-01-03 Abbott Cardiovascular Systems Inc. Reperfusion injury devices
US20130035660A1 (en) 2011-08-01 2013-02-07 Alcyone Lifesciences, Inc. Multidirectional microfluidic drug delivery devices with conformable balloons
US8177704B1 (en) 2011-12-22 2012-05-15 Miracor Medical Systems Gmbh System and method for treating heart tissue
CA2876502A1 (en) 2012-06-28 2014-01-03 Volcano Corporation Intravascular devices, systems, and methods
US9320846B2 (en) 2012-08-28 2016-04-26 Osprey Medical, Inc. Devices and methods for modulating medium delivery
US10010673B2 (en) 2012-08-28 2018-07-03 Osprey Medical, Inc. Adjustable medium diverter
US9999718B2 (en) 2012-08-28 2018-06-19 Osprey Medical, Inc. Volume monitoring device utilizing light-based systems
US10022497B2 (en) 2012-08-28 2018-07-17 Osprey Medical, Inc. Reservoir for collection and reuse of diverted medium
US11219719B2 (en) 2012-08-28 2022-01-11 Osprey Medical, Inc. Volume monitoring systems
CA2896064A1 (en) * 2012-12-21 2014-06-26 Volcano Corporation Functional gain measurement technique and representation
US9844383B2 (en) 2013-05-08 2017-12-19 Embolx, Inc. Devices and methods for low pressure tumor embolization
CN105530986A (zh) 2013-05-08 2016-04-27 埃姆博尔克斯公司 用于经血管肿瘤栓塞的具有综合流量调节的设备及方法
US9877660B2 (en) 2013-11-14 2018-01-30 Medtronic Vascular Galway Systems and methods for determining fractional flow reserve without adenosine or other pharmalogical agent
EP3068287A1 (en) 2013-11-15 2016-09-21 Acist Medical Systems, Inc. Multi-sensor lesion assessment device and method
US9855049B2 (en) 2013-12-11 2018-01-02 Miracor Medical Systems Gmbh System and method for treating heart tissue
WO2015108928A1 (en) 2014-01-14 2015-07-23 Volcano Corporation Systems and methods for evaluating hemodialysis arteriovenous fistula maturation
US8876850B1 (en) 2014-06-19 2014-11-04 Aria Cv, Inc. Systems and methods for treating pulmonary hypertension
WO2017004432A1 (en) 2015-07-01 2017-01-05 Fractyl Laboratories, Inc. Systems, devices and methods for performing medical procedures in the intestine
JP2016168151A (ja) 2015-03-12 2016-09-23 株式会社東海メディカルプロダクツ バルーンカテーテル
AU2017205404B2 (en) 2016-01-04 2020-10-08 Corflow Therapeutics Ag System and methods for treating MVO
US11724030B2 (en) 2018-09-21 2023-08-15 Corflow Therapeutics Ag Method and apparatus for diagnosis and treatment of microvascular dysfunction
US9550046B1 (en) 2016-02-16 2017-01-24 Embolx, Inc. Balloon catheter and methods of fabrication and use
WO2017160270A1 (en) 2016-03-14 2017-09-21 Sanovas, Inc. Modulated drug delivery
US10492805B2 (en) 2016-04-06 2019-12-03 Walk Vascular, Llc Systems and methods for thrombolysis and delivery of an agent
WO2018175485A1 (en) 2017-03-20 2018-09-27 Corflow Therapeutics Ag Combined stent reperfusion system
CA3076035A1 (en) 2017-09-19 2019-03-28 Corflow Therapeutics Ag Intracoronary characterization of microvascular obstruction (mvo) and myocardial infarction
ES2992050T3 (es) 2018-03-09 2024-12-05 Corflow Therapeutics Ag Sistema para diagnosticar y tratar obstrucciones microvasculares
WO2019232452A1 (en) 2018-05-31 2019-12-05 Bernard Andre Microfluidic coronary circulatory model
US12115327B2 (en) 2019-03-05 2024-10-15 Measurement Specialties, Inc. Sensor device and methods of operation for a catheter based treatment of myocardial microvascular obstruction
AU2021274173A1 (en) 2020-05-22 2022-12-22 Corflow Therapeutics Ag Controlled flow infusion microvascular dysfunction diagnostic and therapy

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102596010A (zh) * 2009-08-10 2012-07-18 P2科学有限公司 用于诊断狭窄和其他血流受限之病症的utp
CN105636512A (zh) * 2013-08-14 2016-06-01 南洋理工大学 用于评估血管重建的系统和方法
CN105848573A (zh) * 2013-10-25 2016-08-10 波士顿科学国际有限公司 利用光学传感来确定血流量的导管系统和方法

Also Published As

Publication number Publication date
US11412936B2 (en) 2022-08-16
US20190082976A1 (en) 2019-03-21
JP7249672B2 (ja) 2023-03-31
EP3684247A1 (en) 2020-07-29
CA3076035A1 (en) 2019-03-28
AU2018336787B2 (en) 2024-05-30
AU2018336787A1 (en) 2020-04-23
JP2020534132A (ja) 2020-11-26
CN111655121A (zh) 2020-09-11
WO2019060421A1 (en) 2019-03-28

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