CN111631397A - Health-care composition capable of increasing bone mineral density and preparation method thereof - Google Patents
Health-care composition capable of increasing bone mineral density and preparation method thereof Download PDFInfo
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- 210000000988 bone and bone Anatomy 0.000 title claims abstract description 72
- 239000000203 mixture Substances 0.000 title claims abstract description 43
- 229910052500 inorganic mineral Inorganic materials 0.000 title abstract description 9
- 239000011707 mineral Substances 0.000 title abstract description 9
- 238000002360 preparation method Methods 0.000 title description 4
- 230000037182 bone density Effects 0.000 claims abstract description 40
- 239000002994 raw material Substances 0.000 claims abstract description 29
- 229940036811 bone meal Drugs 0.000 claims abstract description 26
- 239000002374 bone meal Substances 0.000 claims abstract description 26
- 244000068988 Glycine max Species 0.000 claims abstract description 18
- 235000010469 Glycine max Nutrition 0.000 claims abstract description 18
- 229930003316 Vitamin D Natural products 0.000 claims abstract description 18
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims abstract description 18
- GOMNOOKGLZYEJT-UHFFFAOYSA-N isoflavone Chemical compound C=1OC2=CC=CC=C2C(=O)C=1C1=CC=CC=C1 GOMNOOKGLZYEJT-UHFFFAOYSA-N 0.000 claims abstract description 18
- CJWQYWQDLBZGPD-UHFFFAOYSA-N isoflavone Natural products C1=C(OC)C(OC)=CC(OC)=C1C1=COC2=C(C=CC(C)(C)O3)C3=C(OC)C=C2C1=O CJWQYWQDLBZGPD-UHFFFAOYSA-N 0.000 claims abstract description 18
- 235000008696 isoflavones Nutrition 0.000 claims abstract description 18
- 235000019166 vitamin D Nutrition 0.000 claims abstract description 18
- 239000011710 vitamin D Substances 0.000 claims abstract description 18
- 150000003710 vitamin D derivatives Chemical class 0.000 claims abstract description 18
- 229940046008 vitamin d Drugs 0.000 claims abstract description 18
- 241000238557 Decapoda Species 0.000 claims abstract description 17
- RXUWDKBZZLIASQ-UHFFFAOYSA-N Puerarin Natural products OCC1OC(Oc2c(O)cc(O)c3C(=O)C(=COc23)c4ccc(O)cc4)C(O)C(O)C1O RXUWDKBZZLIASQ-UHFFFAOYSA-N 0.000 claims abstract description 16
- HKEAFJYKMMKDOR-VPRICQMDSA-N puerarin Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1C1=C(O)C=CC(C2=O)=C1OC=C2C1=CC=C(O)C=C1 HKEAFJYKMMKDOR-VPRICQMDSA-N 0.000 claims abstract description 16
- 150000002301 glucosamine derivatives Chemical class 0.000 claims abstract description 14
- 235000012054 meals Nutrition 0.000 claims abstract description 13
- 239000006286 aqueous extract Substances 0.000 claims abstract description 10
- 235000011135 Salvia miltiorrhiza Nutrition 0.000 claims abstract description 8
- 235000020696 epimedium extract Nutrition 0.000 claims abstract description 4
- 241000304195 Salvia miltiorrhiza Species 0.000 claims abstract 3
- 238000002156 mixing Methods 0.000 claims description 19
- 238000000227 grinding Methods 0.000 claims description 17
- 238000003756 stirring Methods 0.000 claims description 15
- 238000012216 screening Methods 0.000 claims description 14
- 239000000284 extract Substances 0.000 claims description 12
- 238000000034 method Methods 0.000 claims description 12
- 239000000843 powder Substances 0.000 claims description 11
- 241000251468 Actinopterygii Species 0.000 claims description 10
- 241000282994 Cervidae Species 0.000 claims description 10
- 241001494479 Pecora Species 0.000 claims description 10
- 210000000689 upper leg Anatomy 0.000 claims description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 238000001914 filtration Methods 0.000 claims description 5
- 239000012535 impurity Substances 0.000 claims description 5
- 238000004806 packaging method and process Methods 0.000 claims description 5
- 239000002245 particle Substances 0.000 claims description 5
- 238000007873 sieving Methods 0.000 claims description 5
- 239000007788 liquid Substances 0.000 claims description 2
- 238000012360 testing method Methods 0.000 claims description 2
- 239000002417 nutraceutical Substances 0.000 claims 1
- 235000021436 nutraceutical agent Nutrition 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
- 229930003231 vitamin Natural products 0.000 claims 1
- 229940088594 vitamin Drugs 0.000 claims 1
- 235000013343 vitamin Nutrition 0.000 claims 1
- 239000011782 vitamin Substances 0.000 claims 1
- 150000003722 vitamin derivatives Chemical class 0.000 claims 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract description 22
- 239000011575 calcium Substances 0.000 abstract description 22
- 229910052791 calcium Inorganic materials 0.000 abstract description 22
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract description 12
- 239000011574 phosphorus Substances 0.000 abstract description 12
- 229910052698 phosphorus Inorganic materials 0.000 abstract description 12
- 208000001132 Osteoporosis Diseases 0.000 abstract description 5
- 238000010521 absorption reaction Methods 0.000 abstract description 5
- 206010025476 Malabsorption Diseases 0.000 abstract description 3
- 208000004155 Malabsorption Syndromes Diseases 0.000 abstract description 3
- 230000007812 deficiency Effects 0.000 abstract description 3
- 210000003205 muscle Anatomy 0.000 abstract description 3
- 230000001105 regulatory effect Effects 0.000 abstract description 3
- 239000000126 substance Substances 0.000 abstract description 3
- 239000013589 supplement Substances 0.000 abstract description 3
- 244000132619 red sage Species 0.000 description 5
- 241000893536 Epimedium Species 0.000 description 4
- 235000018905 epimedium Nutrition 0.000 description 4
- 238000000605 extraction Methods 0.000 description 4
- 210000002997 osteoclast Anatomy 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 238000004140 cleaning Methods 0.000 description 3
- 238000011161 development Methods 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 206010065687 Bone loss Diseases 0.000 description 2
- 240000007164 Salvia officinalis Species 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 102000015694 estrogen receptors Human genes 0.000 description 2
- 108010038795 estrogen receptors Proteins 0.000 description 2
- 235000005412 red sage Nutrition 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- 208000010392 Bone Fractures Diseases 0.000 description 1
- 206010017076 Fracture Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 208000001164 Osteoporotic Fractures Diseases 0.000 description 1
- MECHNRXZTMCUDQ-UHFFFAOYSA-N Vitamin D2 Natural products C1CCC2(C)C(C(C)C=CC(C)C(C)C)CCC2C1=CC=C1CC(O)CCC1=C MECHNRXZTMCUDQ-UHFFFAOYSA-N 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000037118 bone strength Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000011841 epidemiological investigation Methods 0.000 description 1
- 229960002061 ergocalciferol Drugs 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000000691 measurement method Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003285 pharmacodynamic effect Effects 0.000 description 1
- 235000001892 vitamin D2 Nutrition 0.000 description 1
- 239000011653 vitamin D2 Substances 0.000 description 1
- MECHNRXZTMCUDQ-RKHKHRCZSA-N vitamin D2 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)/C=C/[C@H](C)C(C)C)=C\C=C1\C[C@@H](O)CCC1=C MECHNRXZTMCUDQ-RKHKHRCZSA-N 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L17/00—Food-from-the-sea products; Fish products; Fish meal; Fish-egg substitutes; Preparation or treatment thereof
- A23L17/40—Shell-fish
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L17/00—Food-from-the-sea products; Fish products; Fish meal; Fish-egg substitutes; Preparation or treatment thereof
- A23L17/70—Comminuted, e.g. emulsified, fish products; Processed products therefrom such as pastes, reformed or compressed products
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
- A23L33/155—Vitamins A or D
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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Abstract
The invention discloses a health care composition capable of increasing bone density, which comprises bone meal, soybean isoflavone, shrimp meal, epimedium extract, glucosamine salt, vitamin D, salvia miltiorrhiza aqueous extract and puerarin, wherein the content ratio of the raw materials is 45-75 percent of the bone meal, 1-3 percent of the soybean isoflavone, 13-27 percent of the shrimp meal, 0.1-1.2 percent of the epimedium extract, 18-35 percent of the glucosamine salt, 2-5 percent of the vitamin D, 0.1-0.5 percent of the salvia miltiorrhiza aqueous extract and 0.15-0.3 percent of the puerarin, the bone meal comprises different bones, and in use, the bone meal can be conveniently absorbed by different people and can supplement calcium, phosphorus in the shrimp meal is an essential element for human bodies, the phosphorus and the calcium are combined into bone mineral substances, phosphorus deficiency caused by phosphorus malabsorption can cause bone mass reduction and finally develops osteoporosis, the level and the bone density of the vitamin D, muscle strength is related, vitamin D is a main regulating factor of calcium absorption, can help a human body to absorb calcium, and can effectively improve the bone density of the human body and maintain the peak value of the bone density for a long time after calcium is absorbed.
Description
Technical Field
The invention relates to the technical field of health-care compositions for increasing bone mineral density, in particular to a health-care composition for increasing bone mineral density and a preparation method thereof.
Background
Bone density, which is known as bone mineral density, is an important indicator of bone strength, expressed in grams per cubic centimeter, as an absolute value, when the bone density value is clinically used, because the absolute values of different bone density detectors are different, a T value is usually used for judging whether the bone density is normal or not, the T value is a relative value, a normal reference value is between-1 and +1, when the T value is lower than-2.5, the bone density is abnormal, is an important mark of bone quality, reflects the osteoporosis degree and an important basis for predicting fracture risk, due to the increasingly improved measurement method and the development of advanced software, the method can be used for different parts, the measurement precision is obviously improved, and the method can be used for clinical pharmacodynamic observation and epidemiological investigation besides the diagnosis of osteoporosis and has obvious superiority in the aspect of predicting osteoporotic fracture;
however, the health care composition on the market at present cannot ensure the absorption of calcium by everyone, and the taste of each person cannot be ensured to be comfortable, so that the health care composition cannot be suitable for different people.
Disclosure of Invention
The invention provides a health-care composition capable of increasing bone mineral density and a preparation method thereof, which can effectively solve the problems that the health-care composition in the current market cannot ensure the absorption of calcium by everyone, and the taste cannot ensure the comfortable taste of each person, so that the health-care composition cannot be suitable for different people.
In order to achieve the purpose, the invention provides the following technical scheme: a health composition for increasing bone density is prepared from bone meal, soybean isoflavone, shrimp powder, herba Epimedii extract, glucosamine salt, vitamin D, Saviae Miltiorrhizae radix water extract and puerarin.
According to the technical scheme, the raw materials comprise 45-75% of bone meal, 1-3% of soybean isoflavone, 13-27% of shrimp meal, 0.1-1.2% of epimedium extraction, 18-35% of glucosamine salt, 78-5% of vitamin D2, 0.1-0.5% of salvia miltiorrhiza aqueous extract and 0.15-0.3% of puerarin.
According to the technical scheme, the bone meal is formed by mixing fish bone, pig bone, cow bone, sheep bone and deer bone, and the content ranges of the bone meal are 30-45% of the fish bone, 10-25% of the pig bone, 15-30% of the cow bone, 10-40% of the sheep bone and 5-10% of the deer bone.
According to the technical scheme, the raw materials comprise 53% of bone meal, 1.8% of soybean isoflavone, 19% of shrimp meal, 0.35% of epimedium extraction, 23% of glucosamine salt, 2.3% of vitamin D, 0.3% of salvia miltiorrhiza aqueous extract and 0.25% of puerarin.
A method for preparing a health composition for increasing bone density comprises the following steps:
s1, sieving: grinding and filtering the raw materials, and removing large particles and impurities by a screening machine to obtain powdery raw materials;
s2, mixing: mixing and stirring the powdery raw materials to prepare a composition, and then detecting;
s3, packaging: the composition is packaged for storage.
According to the technical scheme, the screening filter screen in the screening machine in the S1 is 16-20 meshes;
grinding in the S1 is carried out by a grinding machine, and the grinding times are 3-6;
and the bone meal raw material in the S1 is cleaned, dried and then crushed.
According to the technical scheme, the mixing and stirring speed in the S2 is 500-1500r/min, and the stirring time is 30-45 min.
According to the technical scheme, the items detected in the step S2 are the influence of the length of the femur and the bone density of the rat.
According to the technical scheme, the composition in the S3 is one of powder, tablet and mixed liquid.
According to the technical scheme, the packaged products in the S3 are placed in a cool and ventilating position for storage.
Compared with the prior art, the invention has the beneficial effects that: the invention has scientific and reasonable structure and safe and convenient use, the bone meal comprises different bones, and can be conveniently absorbed by different crowds and supplement calcium when in use, phosphorus in the shrimp meal is an essential element for human bodies, the phosphorus and the calcium are combined into bone mineral substances, the phosphorus deficiency caused by phosphorus malabsorption can cause the reduction of bone mass, and finally the development of osteoporosis is realized, the level of vitamin D is related to bone density and muscle strength density, the vitamin D is a main regulating factor of calcium absorption and can help the human bodies to absorb the calcium, the calcium intake of the bone density of the human bodies can be effectively improved, the peak value of the bone density can be maintained for a long time, the soybean isoflavone can be combined with an estrogen receptor on osteoclasts to reduce the activity of the bone density, the secretion of osteoclasts can be prevented, the bone loss is reduced, in addition, the soybean isoflavone can enhance the utilization of the organism to the calcium and increase the bone density, and the red sage root aqueous extract and the puerarin can, is convenient for the bone to absorb calcium.
Detailed Description
The preferred embodiments described herein are merely illustrative and explanatory of the invention and are not restrictive thereof.
Example 1:
a health composition for increasing bone density is prepared from bone meal, soybean isoflavone, shrimp powder, herba Epimedii extract, glucosamine salt, vitamin D, Saviae Miltiorrhizae radix water extract and puerarin.
According to the technical scheme, the bone powder is formed by mixing fish bone, pig bone, cow bone, sheep bone and deer bone, and the content of the bone powder is 45% of the fish bone, 10% of the pig bone, 15% of the cow bone, 20% of the sheep bone and 10% of the deer bone.
According to the technical scheme, the raw materials comprise 53% of bone meal, 1.8% of soybean isoflavone, 19% of shrimp meal, 0.35% of epimedium extraction, 23% of glucosamine salt, 2.3% of vitamin D, 0.3% of salvia miltiorrhiza aqueous extract and 0.25% of puerarin.
A method for preparing a health composition for increasing bone density comprises the following steps:
s1, sieving: grinding and filtering the raw materials, and removing large particles and impurities by a screening machine to obtain powdery raw materials;
s2, mixing: mixing and stirring the powdery raw materials to prepare a composition, and then detecting;
s3, packaging: the composition is packaged for storage.
According to the technical scheme, the screening filter screen in the screening machine in S1 is 16 meshes;
grinding in S1, grinding by a grinder for 3 times;
and S1, cleaning the bone meal raw material, drying in the air and then crushing.
According to the technical scheme, the mixing and stirring speed in S2 is 1000r/min, and the stirring time is 35 min.
According to the above technical scheme, in S2, the influence of the items of rat femur length and bone density is detected.
According to the technical scheme, the composition in the S3 is powdery.
According to the technical scheme, the packaged products in the S3 are placed in a cool and ventilating position for storage.
Example 2:
a health composition for increasing bone density is prepared from bone meal, soybean isoflavone, shrimp powder, herba Epimedii extract, glucosamine salt, vitamin D, Saviae Miltiorrhizae radix water extract and puerarin.
According to the technical scheme, the bone meal is formed by mixing fish bone, pig bone, sheep bone and deer bone, and the content ranges are 35% of the fish bone, 25% of the pig bone, 30% of the sheep bone and 10% of the deer bone.
According to the technical scheme, the raw materials comprise 53% of bone meal, 1.8% of soybean isoflavone, 19% of shrimp meal, 0.35% of epimedium extraction, 23% of glucosamine salt, 2.3% of vitamin D, 0.3% of salvia miltiorrhiza aqueous extract and 0.25% of puerarin.
A method for preparing a health composition for increasing bone density comprises the following steps:
s1, sieving: grinding and filtering the raw materials, and removing large particles and impurities by a screening machine to obtain powdery raw materials;
s2, mixing: mixing and stirring the powdery raw materials to prepare a composition, and then detecting;
s3, packaging: the composition is packaged for storage.
According to the technical scheme, the screening filter screen in the screening machine in S1 is 20 meshes;
grinding in S1, grinding by a grinder for 3 times;
and S1, cleaning the bone meal raw material, drying in the air and then crushing.
According to the technical scheme, the mixing and stirring speed in S2 is 1500r/min, and the stirring time is 30 min.
According to the above technical scheme, in S2, the influence of the items of rat femur length and bone density is detected.
According to the technical scheme, the composition in the S3 is powdery.
According to the technical scheme, the packaged products in the S3 are placed in a cool and ventilating position for storage.
Example 3:
a health composition for increasing bone density is prepared from bone meal, soybean isoflavone, shrimp powder, herba Epimedii extract, glucosamine salt, vitamin D, Saviae Miltiorrhizae radix water extract and puerarin.
According to the technical scheme, the bone powder is formed by mixing fish bone, pig bone, cow bone, sheep bone and deer bone, and the content of the bone powder is 45% of the fish bone, 10% of the pig bone, 15% of the cow bone, 20% of the sheep bone and 10% of the deer bone.
According to the technical scheme, the raw materials comprise 50% of bone meal, 1.8% of soybean isoflavone, 22% of shrimp meal, 0.35% of epimedium extract, 23% of glucosamine salt, 2.3% of vitamin D, 0.3% of salvia miltiorrhiza aqueous extract and 0.25% of puerarin.
A method for preparing a health composition for increasing bone density comprises the following steps:
s1, sieving: grinding and filtering the raw materials, and removing large particles and impurities by a screening machine to obtain powdery raw materials;
s2, mixing: mixing and stirring the powdery raw materials to prepare a composition, and then detecting;
s3, packaging: the composition is packaged for storage.
According to the technical scheme, the screening filter screen in the screening machine in S1 is 20 meshes;
grinding in S1, grinding by a grinder for 5 times;
and S1, cleaning the bone meal raw material, drying in the air and then crushing.
According to the technical scheme, the mixing and stirring speed in S2 is 1200r/min, and the stirring time is 35 min.
According to the above technical scheme, in S2, the influence of the items of rat femur length and bone density is detected.
According to the technical scheme, the composition in the S3 is powdery.
According to the technical scheme, the packaged products in the S3 are placed in a cool and ventilating position for storage.
The tests were carried out to obtain the following table:
| contrast item | Animal number (only) | Femur weight (g) | Bone calcium content (mg/g) |
| Normal operation group | 10 | 0.638 | 239.8 |
| EXAMPLE 1 group | 10 | 0.652 | 259.3 |
| EXAMPLE 2 group | 10 | 0.640 | 248.7 |
| EXAMPLE 3 group | 10 | 0.646 | 246.3 |
By comparison, it is understood that the density of the femur in examples 1 to 3 is higher than that of the femur in the normal operation group, and that the density of the femur is increased, and compared with each other, it is understood that the effect of example 1 is the best and is most suitable for popularization and use.
Compared with the prior art, the invention has the beneficial effects that: the invention has scientific and reasonable structure and safe and convenient use, the bone meal comprises different bones, and can be conveniently absorbed by different crowds and supplement calcium when in use, phosphorus in the shrimp meal is an essential element for human bodies, the phosphorus and the calcium are combined into bone mineral substances, the phosphorus deficiency caused by phosphorus malabsorption can cause the reduction of bone mass, and finally the development of osteoporosis is realized, the level of vitamin D is related to bone density and muscle strength density, the vitamin D is a main regulating factor of calcium absorption and can help the human bodies to absorb the calcium, the calcium intake of the bone density of the human bodies can be effectively improved, the peak value of the bone density can be maintained for a long time, the soybean isoflavone can be combined with an estrogen receptor on osteoclasts to reduce the activity of the bone density, the secretion of osteoclasts can be prevented, the bone loss is reduced, in addition, the soybean isoflavone can enhance the utilization of the organism to the calcium and increase the bone density, and the red sage root aqueous extract and the puerarin can, is convenient for the bone to absorb calcium.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that changes may be made in the embodiments and/or equivalents thereof without departing from the spirit and scope of the invention. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (10)
1. A health composition capable of increasing bone density, which is characterized in that: the raw materials include bone meal, soybean isoflavone, shrimp meal, herba Epimedii extract, glucosamine salt, vitamin D, Saviae Miltiorrhizae radix water extract and puerarin.
2. The health composition for increasing bone density as claimed in claim 1, wherein the raw materials comprise bone meal 45-75%, soybean isoflavone 1-3%, shrimp meal 13-27%, herba Epimedii extract 0.1-1.2%, glucosamine salt 18-35%, vitamin D2-5%, Saviae Miltiorrhizae radix water extract 0.1-0.5% and puerarin 0.15-0.3%.
3. The health composition for increasing bone density as claimed in claim 2, wherein the bone powder is a mixture of fish bone, pig bone, cow bone, sheep bone and deer bone, and the content ranges from 30% to 45% of fish bone, 10% to 25% of pig bone, 15% to 30% of cow bone, 10% to 40% of sheep bone and 5% to 10% of deer bone.
4. The health composition capable of increasing bone density according to claim 3, wherein the raw materials comprise 53% of bone meal, 1.8% of soybean isoflavone, 19% of shrimp meal, 0.35% of epimedium extract, 23% of glucosamine salt, 2.3% of vitamin D, 0.3% of salvia miltiorrhiza aqueous extract and 0.25% of puerarin.
5. A method for preparing a nutraceutical composition for increasing bone density, as defined in any of claims 1-4, comprising the steps of:
s1, sieving: grinding and filtering the raw materials, and removing large particles and impurities by a screening machine to obtain powdery raw materials;
s2, mixing: mixing and stirring the powdery raw materials to prepare a composition, and then detecting;
s3, packaging: the composition is packaged for storage.
6. The method for preparing a health composition for increasing bone density as claimed in claim 5, wherein the screen of the screening machine in S1 is 16-20 mesh;
grinding in the S1 is carried out by a grinding machine, and the grinding times are 3-6;
and the bone meal raw material in the S1 is cleaned, dried and then crushed.
7. The method as claimed in claim 5, wherein the mixing and stirring speed in S2 is 500-1500r/min, and the stirring time is 30-45 min.
8. The method for preparing a health composition capable of increasing bone density as claimed in claim 5, wherein the test items in S2 are rat femur length and bone density.
9. The method of claim 5, wherein the composition of S3 is in the form of one of powder, tablet, and liquid.
10. The method for preparing a health composition capable of increasing bone density as claimed in claim 5, wherein the packaged composition of S3 is stored in a cool and ventilated place.
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