CN111616064A - Animal conditioned position preference experimental device - Google Patents
Animal conditioned position preference experimental device Download PDFInfo
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K1/00—Housing animals; Equipment therefor
- A01K1/02—Pigsties; Dog-kennels; Rabbit-hutches or the like
- A01K1/03—Housing for domestic or laboratory animals
- A01K1/031—Cages for laboratory animals; Cages for measuring metabolism of animals
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K29/00—Other apparatus for animal husbandry
- A01K29/005—Monitoring or measuring activity, e.g. detecting heat or mating
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K3/00—Pasturing equipment, e.g. tethering devices; Grids for preventing cattle from straying; Electrified wire fencing
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K7/00—Watering equipment for stock or game
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Abstract
The invention discloses an animal conditioned position preference experiment device which comprises at least two conditioning boxes, transition boxes, first baffles and second baffles, wherein the conditioning boxes are arranged at intervals, each conditioning box is provided with a movable opening, two ends of each transition box are open and are respectively arranged towards the movable openings of two adjacent conditioning boxes, two ends of each transition box are respectively detachably connected with the two conditioning boxes, the transition boxes are provided with animal inlet plates, the number of the first baffles is at least two, each first baffle is matched on each conditioning box, the first baffles can seal the movable openings, the second baffles are matched on the transition boxes, and the second baffles are used for sealing animal inlets. The animal conditioned position preference experiment device is simple in structure and low in manufacturing and using cost.
Description
Technical Field
The invention relates to the technical field of animal experiment devices, in particular to an animal conditioned position preference experiment device.
Background
The conditional site preference behavior model is one of the main paradigms for studying learning memory and drug addiction, at present, rodents are mainly used as experimental subjects in the conditional site preference study, and the used devices are designed based on the body size, the physiology and the living characteristics of the rodents. Although large animals, particularly non-human primates, are increasingly being used in learning memory and drug addiction studies, due to the large individual and more complex behaviors, the current conditional site preference test apparatus for large animals utilizes three adjacent rooms as the training and testing place, with the three rooms intercommunicating with one another with doors, and requires that the animal be placed in the room with the tether during training and testing. The disadvantages of the existing conditional position preference experimental device are as follows:
firstly, the method comprises the following steps: the tethering means affects the freedom of movement of the animal to some extent and possibly also the behaviour of the animal.
Secondly, the method comprises the following steps: the space occupied by the training and detecting places is large, the manufacturing cost is high, and the requirements can not be met by common experimental places.
Disclosure of Invention
The invention aims to provide an animal conditioned location preference experimental device which is simple in structure, low in manufacturing and using cost and low in experimental error.
In order to achieve the above technical effects, the technical solution of the animal conditioned location preference experiment apparatus of this embodiment is as follows:
the invention discloses an animal conditioned location preference experimental device, which comprises: the device comprises at least two conditioning boxes, wherein the conditioning boxes are arranged at intervals, and each conditioning box is provided with a movable port; the two ends of the transition box body are open and are respectively arranged towards the movable openings of the two adjacent conditioning boxes, the two ends of the transition box body are respectively detachably connected with the two conditioning boxes, and an animal inlet is formed in the transition box body; at least two first baffles, wherein each first baffle is matched on the conditioning box and can seal the movable opening; and the second baffle is matched with the transition box body and used for sealing the animal inlet.
In some embodiments, at least one side wall of the conditioning chamber is a grid, and the animal conditioning site preference experiment apparatus further comprises: the extrusion spare, the extrusion spare is at least two, and every the extrusion spare slidable is established in the conditioning case, the extrusion spare is used for promoting the laboratory animal towards the activity mouth removes.
In some embodiments, a first sliding groove is formed in the conditioning box, the first sliding groove is located on the outer side of the movable opening, and the first baffle is slidably arranged in the first sliding groove.
In some embodiments, a second chute is provided on the transition box body, the second chute is located outside the animal entrance, and the second baffle is slidably provided in the second chute.
In some embodiments, the animal conditioned location preference experimental apparatus further comprises a connecting buckle, the connecting buckle is provided with a clamping hole, and the transition box body and the conditioning box are provided with clamping protrusions matched with the clamping hole; or the connecting buckle is provided with the clamping protrusion, and the transition box body and the conditioning box are provided with the clamping hole matched with the clamping protrusion.
In some embodiments, one of the transition box body and the conditioning box body is provided with a positioning hole, and the other is provided with a positioning column matched with the positioning hole.
In some embodiments, a removable background plate is provided within the conditioning chamber; and/or; and a food groove is arranged in the conditioning box and used for placing food of the experimental animal.
In some embodiments, the conditioning tank is provided with a sliding wheel at the bottom.
In some embodiments, the animal conditioned place preference experiment apparatus further comprises a shooting device, and the shooting device is used for shooting the experimental animal.
In some embodiments, each of the conditioning boxes further comprises an expansion interface for installing a behavioural experiment module.
According to the animal conditioned location preference experiment device, the conditioned box and the transition box body are detachably connected, so that the structure of the whole experiment device is simplified, the use and manufacturing cost of the experiment device is reduced, and the experiment device is convenient to carry. Because the conditioning box and the transition box are not internally provided with the tie-down equipment, the experimental animal is in a free-moving state in the conditioning box and the transition box, the moving automation degree of the experimental animal is ensured, and the error of the conditioning preference experiment is reduced.
Additional aspects and advantages of the invention will be set forth in part in the description which follows and, in part, will be obvious from the description, or may be learned by practice of the invention.
Drawings
Fig. 1 is a schematic structural diagram of an animal conditioned place preference experimental apparatus according to an embodiment of the present invention.
Reference numerals:
1. a conditioning box; 11. a movable opening; 12. expanding an interface; 2. a transition box body; 21. an animal inlet; 3. a first baffle plate; 4. a second baffle; 5. an extrusion; 6. connecting a buckle; 7. a background plate; 8. a food trough; 9. a behavioral experiment module; 10. a sliding wheel.
Detailed Description
In order to make the technical problems solved, the technical solutions adopted and the technical effects achieved by the present invention clearer, the technical solutions of the present invention are further described below by way of specific embodiments with reference to the accompanying drawings.
In the description of the present invention, it is to be understood that the terms "central," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," "circumferential," and the like are used in the orientations and positional relationships indicated in the drawings for convenience in describing the invention and to simplify the description, and are not intended to indicate or imply that the referenced device or element must have a particular orientation, be constructed and operated in a particular orientation, and are not to be considered limiting of the invention.
Furthermore, features defined as "first" and "second" may explicitly or implicitly include one or more of the features for distinguishing between descriptive features, non-sequential, non-trivial and non-trivial. In the description of the present invention, "a plurality" means two or more unless otherwise specified.
In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
The specific structure of the animal conditioned place preference test apparatus according to the embodiment of the present invention will be described with reference to fig. 1.
As shown in fig. 1, the animal conditioned location preference experiment device according to the embodiment of the present invention includes a conditioning box 1, at least two conditioning boxes 1, first baffles 3 and second baffles 4, where the conditioning boxes 1 are arranged at intervals, each conditioning box 1 has a movable opening 11, two ends of the transition box 2 are open and respectively arranged toward the movable openings 11 of two adjacent conditioning boxes 1, two ends of the transition box 2 are detachably connected to the two conditioning boxes 1, an animal inlet 21 is arranged on the transition box 2, the first baffles 3 are multiple, each first baffle 3 is matched on the conditioning box 1, the first baffle 3 can seal the movable opening 11, the second baffles 4 are matched on the transition box 2, and the second baffles 4 are used for sealing the animal inlet 21.
First, in the present invention, the number of the conditioning boxes 1 can be selected according to actual needs, and the following description will be made on the principle of the animal conditioned place preference experimental apparatus of the present invention by taking the case where the number of the conditioning boxes 1 is two.
It can be understood that because transition box 2 and conditioning case 1 can dismantle the connection, only need to dismantle transition box 2 from conditioning case 1 and can realize the transport of the animal conditioned position preference experimental apparatus of this embodiment like this when needs transport, compare the current technical scheme who adopts a plurality of rooms as the experiment place, the animal conditioned position preference experimental apparatus of this embodiment's simple structure, manufacturing cost is lower, and the transport is convenient.
In particular, the conditioning site preference is mainly used for studying reward memory related to drugs, and the principle is the classic conditioning of pavlov, namely after repeatedly combining the reward effect of drugs with a neutral environment, experimental animals combine the neutral environment with the reward effect of drugs, thereby showing the preference for the environment. The conditional location preference process typically includes three phases: an adaptation phase, a conditioning training phase and a testing phase.
In the adaptation stage, after the experimental animal is put into transition box 2, adopt the second baffle to close the animal entry 21 of transition box, then demolish two first baffles 3 for transition box 2 and two conditioning case 1 intercommunications, the experimental animal can freely make a round trip to shuttle between two conditioning case 1, because two conditioning case 1 have done balanced design in sense organ experiences such as vision, sense of hearing and sense of touch, the experimental animal can not produce obvious position preference to two conditioning case 1. Thus, the residence time of the experimental animals in the two conditioning chambers 1 is similar.
In the conditioning training stage, the first baffle plate 3 is installed back to the conditioning boxes 1, so that the conditioning boxes 1 are separated from the transition box body 2, the experimental animal is limited in one conditioning box 1, the experimental animal is injected with reward or addiction drugs to perform drug conditioning, the reward effect of the drugs is combined with the corresponding conditioning box 1 by the experimental animal, and the experimental animal is limited in the other conditioning box 1 and injected with physiological saline at the next conditioning training, so that the experimental animal can combine the conditioning box 1 with the non-reward effect because the physiological saline has no reward effect.
In the testing stage, the two first baffle plates 3 are removed again to enable the transition box body 2 to be communicated with the conditioning boxes 1, so that the experimental animals can freely shuttle between the two conditioning boxes 1, and the conditioned experimental animals can generate preference for the drug-related conditioning boxes 1, thereby staying for a longer time. The study memory and mental dependence of the experimental animals on the drug production were evaluated by comparing the preference of the acclimation phase and the test phase for the conditioning kit 1.
According to the above description, in the whole experiment process, the experimental animal is in the automatic moving state, and no matter in the conditioning box 1 or the transition box body 2, the experimental animal is not required to be tethered, so that the freedom of movement of the experimental animal is ensured, and the error brought by the tethering device to the conditioning preference experiment is avoided.
According to the animal conditioned location preference experiment device, the conditioning box 1 and the transition box body 2 which are detachably connected are arranged, so that the structure of the whole experiment device is simplified, the use and manufacturing cost of the experiment device is reduced, and the experiment device is convenient to carry. Because the condition box 1 and the transition box body 2 are not provided with the tying devices, the experimental animal is in a free-moving state in the condition box 1 and the transition box body 2, the moving automation degree of the experimental animal is ensured, and the error of the condition preference experiment is reduced.
In some embodiments, as shown in fig. 1, at least one side wall of the conditioning case 1 is a grating, the animal conditioning position preference experiment apparatus further comprises at least two pressing members 5, each pressing member 5 is slidably provided in the conditioning case 1, and the pressing members 5 are used for pushing the experimental animal to move toward the movable opening 11.
It will be appreciated that, after the end of the actual experiment, when the first shutter 3 is pushed back, the moving presser 5 can press the experimental animal at the corner near the first shutter 3 in the conditioning case 1. Because at least one of the side walls of the conditioning box 1 is the grating, experimenters can directly carry out operations such as medicine injection, venous blood sampling and the like on experimental animals through the grating, and the timeliness of medicine injection is ensured. In addition, after the actual experiment, when first baffle 3 was taken out, remove extruded article 5 and can catch up the laboratory animal from conditioning case 1 in the transition box 2 to made things convenient for the experimenter to take out the laboratory animal from whole device.
It should be added that the extrusion member 5 can select an extrusion plate and an extrusion rod according to actual needs, and in order to ensure that the extrusion member 5 can stably slide, the conditioning box 1 can be provided with a guide rod, and the extrusion member 5 is arranged on the guide rod in a penetrating manner.
In some embodiments, the conditioning box 1 is provided with a first sliding groove located outside the movable opening 11, and the first baffle 3 is slidably disposed in the first sliding groove. It can be understood that, first baffle 3 slidable is established in first spout, has made things convenient for the experimenter to take out or push first baffle 3 in the experimentation on the one hand, and stability when on the other hand had guaranteed first baffle 3 and the cooperation of conditioning case 1 has avoided first baffle 3 to be connected the experimental animals that the unstability leads to with conditioning case 1 and has scurried the phenomenon emergence.
In some embodiments, the transition box 2 is provided with a second chute located outside the animal entrance 21, and the second apron 4 is slidably provided in the second chute. It can be understood that second baffle 4 slidable is established in the second spout, has made things convenient for the experimenter to take out or push second baffle 4 in the experimentation on the one hand, and on the other hand has guaranteed the stability when second baffle 4 and conditioning case 1 cooperate, and the phenomenon of the experimental animal that has avoided second baffle 4 and conditioning case 1 to be connected the unstable laboratory animal that leads to escapes transition box 2 takes place.
In some embodiments, as shown in fig. 1, the animal conditioning position preference experimental apparatus further includes a connecting buckle 6, the connecting buckle 6 is provided with a clamping hole, and the transition box body 2 and the conditioning box 1 are provided with clamping protrusions matched with the clamping hole; or, the connecting buckle 6 is provided with a clamping protrusion, and the transition box body 2 and the conditioning box 1 are provided with a clamping hole matched with the clamping protrusion.
It can be understood that the connection between the transition box body 2 and the conditioning box 1 is facilitated by adopting a matching structure of the clamping hole and the clamping protrusion, so that the installation and the disassembly of the transition box body 2 and the conditioning box 1 are facilitated. In addition, the connection stability of the transition box body 2 and the conditioning box 1 can be ensured, and the phenomenon that the experimental animal breaks the transition box body 2 and the conditioning box 1 to escape from the experimental device is avoided.
In some embodiments, one of the transition box body 2 and the conditioning box 1 is provided with a positioning hole, and the other is provided with a positioning column matched with the positioning hole. From this, need not external connecting piece and realize transition box 2 and the connection of conditioning case 1 to further simplified the structure of animal conditioning position preference experimental apparatus, reduced experimental apparatus's manufacturing cost.
In some embodiments, as shown in FIG. 1, a removable background plate 7 is provided within the conditioning chamber 1.
It should be noted that, the conditioning box 1 is internally provided with a detachable background plate 7, and the background plate 7 is designed in a balanced manner on colors and patterns, so that the experimental animal can distinguish two environments more easily, and has no natural preference in an adaptation stage, thereby ensuring the accuracy of an experimental result.
In some embodiments, as shown in fig. 1, a food tank 8 is provided in the conditioning box 1, and the food tank 8 is used for placing the food of the experimental animal. The additionally arranged food groove 8 can promote the experimental animal to take food through climbing, so that the exercise behavior of the experimental animal is more comprehensively evaluated.
In some embodiments, as shown in fig. 1, the bottom of conditioning case 1 is provided with a sliding wheel 10. From this, made things convenient for the transport and the transportation of animal conditioning position preference experimental apparatus.
In some embodiments, the animal conditioned place preference experiment device further comprises a camera for taking a picture of the experimental animal. Therefore, the real-time movement of the experimental animal is comprehensively monitored, and the movement behavior of the experimental animal is more comprehensively evaluated.
In some embodiments, as shown in fig. 1, each conditioning box 1 further comprises an expansion interface 12, and the expansion interface 12 is used for installing the behavioural experiment module 9. It can be understood that the behavioristics experiment module 9 can be a touch screen or an operation panel, and can simultaneously perform medicine-related learning memory detection and advanced cognitive function detection in the experiment process of conditional position preference, thereby expanding the application range of the animal conditional position preference experiment device.
Example (b):
the specific structure of an animal conditioned place preference test apparatus according to a specific embodiment of the present invention will be described with reference to fig. 1.
The animal conditioning position preference experimental apparatus of this embodiment includes two conditioning case 1, transition box 2, two first baffles 3, second baffle 4, two extruded articles 5, connect buckle 6, background board 7 and food groove 8, two 1 interval settings of conditioning case, every conditioning case 1 all has a movable mouthful 11 and expands interface 12, movable mouthful 11 and expansion interface 12 are located two lateral walls of the relative setting of conditioning case 1 respectively, the movable mouthful 11 of two conditioning cases 1 correspond and set up. The front panel of the conditioning box 1 is designed to be transparent acrylic, the rest panels are stainless steel grids, and high-definition cameras can be placed in the front, the side and the upper part of the conditioning box 1. Each first shutter 3 is fitted to the conditioning tank 1, and the first shutter 3 can close the movable opening 11 of the conditioning tank 1. Each conditioning box 1 is provided with a detachable background plate 7 and a food groove 8 connected to the top wall of the conditioning box 1. Each conditioning box 1 further comprises an expansion interface 12, and the expansion interface 12 is used for installing the behavioural experiment module 9.
The both ends of transition box 2 are opened and are corresponded two adjacent conditioning case 1's movable port 11 respectively and set up, are equipped with animal entry 21 on the transition box 2, and second baffle 4 cooperates on transition box 2, and second baffle 4 is used for sealing animal entry 21. Each presser 5 is slidably provided in the conditioning case 1, and the presser 5 is used to push the laboratory animal toward the movable opening 11. The connecting buckle 6 is provided with a clamping hole, and the transition box body 2 and the conditioning box 1 are provided with clamping protrusions matched with the clamping hole.
The experimental procedure of the animal conditioned place preference experimental apparatus of this example is as follows:
in the adaptation phase: the second baffle 4 is drawn out, the transfer cage with the experimental animal is aligned with the animal inlet 21 of the transition box body 2, the second baffle 4 is reset to close the transition box body 2 after the experimental animal enters the transition box body 2, and the transition box body 2 is communicated with the conditioning box body 1 by drawing out the two first baffles 3. At this moment, the experimental animal can freely shuttle back and forth between the two conditioning boxes 1 through the transition box body 2 within a certain time, and because the two conditioning boxes 1 are designed in a balanced manner in sense experiences such as vision, hearing and touch, the experimental animal does not generate obvious position preference to the two conditioning boxes 1, and the residence time of the experimental animal in the two conditioning boxes 1 is similar.
In the conditioning stage: after the experimental animal is placed into one of the conditioning boxes 1, the first baffle 3 is reset, so that the two conditioning boxes 1 are separated from the transition box body 2, the experimental animal is limited on one side of the conditioning box 1 through the extrusion piece 5, the experimental animal is injected with a reward medicine, then the extrusion piece 5 is loosened, and the experimental animal is left in the conditioning box 1 for at least one hour for conditioning. The following day, the same procedure limits the experimental animals to another conditioning chamber 1 and injects physiological saline, and then leaves the conditioning chamber 1 for at least one hour for conditioning.
In the testing stage: the two first baffles 3 are withdrawn again, so that the experimental animal can freely shuttle between the two conditioning boxes 1 within a certain time, and the conditioned experimental animal has a preference for the drug-related conditioning box 1, so that the experimental animal can stay for a longer time. The study memory and mental dependence of the experimental animals on the drug production were evaluated by comparing the preference of the acclimation phase and the test phase for the conditioning kit 1.
The animal conditioned location preference experiment device of the embodiment has the following advantages:
firstly, the method comprises the following steps: the floor area is small, the structure is simple, and the manufacturing cost is low;
secondly, the method comprises the following steps: the medicine can be directly injected in the conditioning box 1, so that the effectiveness of the medicine is improved;
thirdly, the method comprises the following steps: the transition box body 2 can be butted with a transfer cage of the experimental animal without animal tying equipment, so that the experimental animal can move freely;
fourthly: the front panel of the conditioning box 1 is designed to be transparent acrylic, the other panels are stainless steel grids, and cameras are arranged in front of, on the side of and above the conditioning box, so that the motion trail of the experimental animal can be conveniently recorded;
fifth, the method comprises the following steps: the transition box body 2 and the conditioning boxes 1 on the two sides are detachably arranged, so that the transition box has high portability;
sixth: the side surface of the conditioning box 1 is provided with an expansion interface 12 which can be combined with a touch screen, an operation panel and other behavioral training modules and can simultaneously perform medicine-related learning memory detection and advanced cognitive function detection;
seventh: the replaceable background plate 7 with different colors and patterns is designed at the rear part in the conditioning box 1, so that the animals can be helped to better distinguish the two conditioning boxes 1, and a conditioning position preference experiment is better carried out;
eighth: the method is suitable for the experimental study of conditioned location preference of large animals, and can be widely applied to drug screening, preclinical animal tests of drugs, addiction, pain and drug dependence study.
In the description herein, references to the description of "some embodiments," "other embodiments," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The above description is only a preferred embodiment of the present invention, and for those skilled in the art, the present invention should not be limited by the description of the present invention, which should be interpreted as a limitation.
Claims (10)
1. An animal conditioned place preference experimental apparatus, comprising:
the device comprises at least two conditioning boxes (1), wherein the conditioning boxes (1) are arranged at intervals, and each conditioning box (1) is provided with a movable opening (11);
the two ends of the transition box body (2) are open and are respectively arranged towards the movable openings (11) of the two adjacent conditioning boxes (1), the two ends of the transition box body (2) are respectively detachably connected with the two conditioning boxes (1), and an animal inlet (21) is formed in the transition box body (2);
at least two first baffles (3), wherein each first baffle (3) is matched on the conditioning box (1), and the first baffles (3) can close the movable opening (11);
a second baffle (4), the second baffle (4) being fitted on the transition box (2), the second baffle (4) being for closing the animal entrance (21).
2. Animal conditioned place preference experimental device according to claim 1, characterized in that at least one side wall of the conditioning tank (1) is a grid, the animal conditioned place preference experimental device further comprising: the extrusion spare (5), extrusion spare (5) are at least two, and every extrusion spare (5) slidable is established in conditioning case (1), extrusion spare (5) are used for promoting the laboratory animal towards the activity mouth (11) removes.
3. The animal conditioning location preference experimental apparatus according to claim 1, characterized in that the conditioning box (1) is provided with a first chute which is located outside the movable opening (11), and the first baffle (3) is slidably provided in the first chute.
4. The animal conditioned place preference experimental apparatus according to claim 1, wherein a second chute is provided on the transition box body (2), the second chute being located outside the animal entrance (21), the second baffle (4) being slidably provided in the second chute.
5. The animal conditioned place preference experimental device according to claim 1, further comprising a connecting buckle (6), wherein the connecting buckle (6) is provided with a clamping hole, and the transition box body (2) and the conditioning box (1) are provided with clamping protrusions matched with the clamping hole; or the connecting buckle (6) is provided with the clamping protrusion, and the transition box body (2) and the conditioning box (1) are provided with the clamping hole matched with the clamping protrusion.
6. The animal conditioned place preference experiment device according to claim 1, wherein one of the transition box body (2) and the conditioning box (1) is provided with a positioning hole, and the other is provided with a positioning post matched with the positioning hole.
7. An animal conditioned place preference experiment device according to any of claims 1-6, characterized in that a removable background plate (7) is provided inside the conditioning box (1); and/or;
a food groove (8) is formed in the conditioning box (1), and the food groove (8) is used for placing food of experimental animals.
8. Animal conditioned place preference test device according to any of claims 1-6, characterized in that the bottom of the conditioning box (1) is provided with a sliding wheel (10).
9. The animal conditioned place preference test apparatus according to any one of claims 1 to 6, further comprising a photographing apparatus for photographing the test animal.
10. Animal conditioning situational preference experimental apparatus according to any of claims 1-6, characterized in that each conditioning box (1) further comprises an expansion interface (12), said expansion interface (12) being used for installing a behavioural experimental module (9).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010582496.3A CN111616064A (en) | 2020-06-23 | 2020-06-23 | Animal conditioned position preference experimental device |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202010582496.3A CN111616064A (en) | 2020-06-23 | 2020-06-23 | Animal conditioned position preference experimental device |
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| CN111616064A true CN111616064A (en) | 2020-09-04 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113142073A (en) * | 2021-05-14 | 2021-07-23 | 广西盛思蓝生物医药技术有限公司 | Multifunctional integrated cage for experimental non-human primates and use method thereof |
| WO2024098485A1 (en) * | 2022-11-08 | 2024-05-16 | 深圳先进技术研究院 | Apparatus for testing conditioned place preference of animal |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113142073A (en) * | 2021-05-14 | 2021-07-23 | 广西盛思蓝生物医药技术有限公司 | Multifunctional integrated cage for experimental non-human primates and use method thereof |
| CN113142073B (en) * | 2021-05-14 | 2023-05-30 | 广西盛思蓝生物医药技术有限公司 | Multifunctional integrated cage for non-human primate experimental animals and use method thereof |
| WO2024098485A1 (en) * | 2022-11-08 | 2024-05-16 | 深圳先进技术研究院 | Apparatus for testing conditioned place preference of animal |
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