CN111601612A - A Chinese medicinal composition for treating deficiency cold, and its preparation method - Google Patents
A Chinese medicinal composition for treating deficiency cold, and its preparation method Download PDFInfo
- Publication number
- CN111601612A CN111601612A CN201880028270.XA CN201880028270A CN111601612A CN 111601612 A CN111601612 A CN 111601612A CN 201880028270 A CN201880028270 A CN 201880028270A CN 111601612 A CN111601612 A CN 111601612A
- Authority
- CN
- China
- Prior art keywords
- parts
- chinese medicine
- traditional chinese
- raw materials
- cold
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Anesthesiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
A Chinese medicinal composition for treating deficiency cold and its preparation method are provided. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in proportion: 10-50 parts of poria cocos, 10-50 parts of bighead atractylodes rhizome, 15-75 parts of dried ginger and 5-15 parts of monkshood. The Chinese medicinal composition has effects of warming yang, dispelling cold, promoting diuresis and resolving fluid retention. Has curative effect or relieving effect on symptoms caused by deficiency-cold, such as heaviness, pain or swelling of whole body, cold limbs, insomnia, depression, abdominal pain with diuresis, oliguria or frequent micturition, pale tongue, and slippery tooth-mark.
Description
The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition capable of treating deficiency-cold and a preparation method thereof.
Deficient cold can cause wind-cold-dampness to invade and further cause arthralgia and myalgia, and is clinically manifested as chills, aversion to cold, heaviness of the whole body, pain or slight swelling, cold limbs, insomnia, sleeplessness, depression, pain in abdomen with diarrhea, scanty or frequent urine, and pale tongue with water and slippery teeth mark. Even with cough and asthma due to deficiency-cold, vertigo, and palpitation. In the existing traditional Chinese medicine compound, no traditional Chinese medicine composition with obvious curative effect on deficiency-cold of human bodies exists.
Disclosure of Invention
The technical problem to be solved by the invention is as follows: can be used for treating various diseases caused by deficiency cold.
In order to solve the technical problems, the invention discloses a traditional Chinese medicine composition capable of treating deficiency-cold, which is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10-50 parts of poria cocos, 10-50 parts of bighead atractylodes rhizome, 15-75 parts of dried ginger and 5-15 parts of monkshood.
Further, the traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 45 parts of poria cocos, 30 parts of bighead atractylodes rhizome, 45 parts of dried ginger and 5-15 parts of monkshood.
Further, the traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10-50 parts of poria cocos, 40-50 parts of bighead atractylodes rhizome, 15-75 parts of dried ginger and 5-15 parts of monkshood.
Further, the traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 45 parts of poria cocos, 45 parts of bighead atractylodes rhizome, 45 parts of dried ginger and 5-15 parts of monkshood.
In addition, a preparation method of the traditional Chinese medicine composition is also disclosed, and the preparation method specifically comprises the following steps:
s1, mixing, namely weighing the traditional Chinese medicine raw materials of poria cocos, bighead atractylodes rhizome, dried ginger and monkshood according to the mixture ratio;
s2, soaking, namely soaking the weighed traditional Chinese medicine raw materials in water;
s3, decocting, heating and decocting the soaked traditional Chinese medicine raw materials;
s4, filtering, and filtering after the decoction is finished to remove the dregs of a decoction to obtain the decoction.
Further, in the step of S2 soaking, water is added according to the amount 9-11 times of the total weight of the traditional Chinese medicine raw materials, and the soaking is carried out for 20-40 min.
Further, in the S3 decoction step, the decoction is heated to boiling and then continuously decocted for 90-120min at the temperature of 100-115 ℃.
Further, in the step S4, the volume of the finally obtained decoction is 3/8-1/2 of the volume corresponding to the added water amount.
The traditional Chinese medicine composition disclosed by the invention has the effects of warming yang, dispelling cold and promoting diuresis to remove fluid retention. The traditional Chinese medicine composition has a curative effect or a remarkable relieving effect on symptoms such as heaviness, pain or slight swelling of the whole body, cold limbs, insomnia, depression, abdominal pain with diarrhea, scanty urine or frequent micturition, and watery and slippery tooth marks on tongue, and is suitable for clinical application.
[ correction 28.12.2018 according to rules 91 ] the following description of the invention is provided with reference to the accompanying drawings
[ correcting 28.12.2018 according to the rules of thin 91 ] FIG. 1 is a flow chart of a method for preparing a Chinese medicinal composition for treating deficiency-cold
In order to explain technical contents, structural features, and objects and effects of the present invention in detail, the following description is given in detail with reference to the embodiments.
Example 1
A traditional Chinese medicine composition for treating deficiency-cold is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10g of poria cocos, 10g of bighead atractylodes rhizome, 75g of dried ginger and 15g of monkshood.
[ 28.12.2018 is corrected according to the rules of the book 91 ] with reference to the figure 1, when in preparation, 10g of tuckahoe, 10g of atractylodes macrocephala, 75g of dried ginger and 15g of monkshood are respectively weighed and added into a traditional Chinese medicine decocting pot together. Wherein, the tuckahoe has the efficacies of relieving the dampness seepage and diuresis, benefiting the spleen and stomach, calming the heart and tranquilizing the mind, treating difficult urination, edema and fullness, expectoration, vomiturition and the like. The rhizoma atractylodis macrocephalae has the effects of tonifying qi and spleen, eliminating dampness and promoting diuresis, suppressing sweating, dysuria, edema and the like. Gan Jiang warms the middle energizer to dispel cold, returns yang to activate meridians, eliminates dampness to eliminate phlegm, warms the lung to resolve retention, and has certain efficacy in treating abdominal psychroalgia, vomiting and diarrhea, chronic cough with dyspnea due to lung cold, excessive phlegm and thin and clear. The monkshood has the effects of restoring yang and rescuing collapse, tonifying fire and supporting yang, dispelling cold and removing dampness, dispelling cold and relieving pain and the like. The traditional Chinese medicine composition is mainly used for treating or relieving deficiency-cold, and the white peony root, which is a component, only increases cold to aggravate the disease condition, so cold medicinal materials such as white peony root and the like cannot be added into the formula. Then 1200ml of water is added into the decocting pot to soak the traditional Chinese medicine raw materials for 20 min. Then heating the decocting pot with strong fire until boiling in the decocting pot, adjusting to small fire, and keeping the heating temperature at 100-. Turning off the fire, filtering the solid-liquid mixture in the decocting pot, and removing the residue to obtain 580ml decoction.
Example 2
A traditional Chinese medicine composition for treating deficiency-cold is prepared from the following traditional Chinese medicine raw materials in parts by weight: 45g of poria cocos, 30g of bighead atractylodes rhizome, 45g of dried ginger and 5g of monkshood.
During preparation, 45g of poria cocos, 30g of bighead atractylodes rhizome, 45g of dried ginger and 5g of monkshood are weighed respectively and added into a traditional Chinese medicine decocting tank together. Then 1200ml of water is added into the decocting pot to soak the traditional Chinese medicine raw materials for 30 min. Then heating the decocting pot with strong fire until boiling in the decocting pot, adjusting to small fire, and keeping the heating temperature at 100-. Turning off the fire, filtering the solid-liquid mixture in the decocting pot, and removing the residue to obtain 600ml of decoction.
Example 3
A traditional Chinese medicine composition for treating deficiency-cold is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10g of poria cocos, 40g of bighead atractylodes rhizome, 75g of dried ginger and 15g of monkshood.
During preparation, 10g of poria cocos, 40g of bighead atractylodes rhizome, 75g of dried ginger and 15g of monkshood are weighed respectively and added into a traditional Chinese medicine decocting tank together. 1400ml of water is added into the decocting pot to soak the traditional Chinese medicine raw materials for 30 min. Then heating the decocting pot with strong fire until boiling in the decocting pot, adjusting to small fire, and keeping the heating temperature at 100-. Turning off the fire, filtering the solid-liquid mixture in the decocting pot, and removing the residue to obtain 600ml of decoction.
Example 4
A traditional Chinese medicine composition for treating deficiency-cold is prepared from the following traditional Chinese medicine raw materials in parts by weight: 45g of poria cocos, 45g of bighead atractylodes rhizome, 45g of dried ginger and 5g of monkshood.
During preparation, 45g of poria cocos, 45g of bighead atractylodes rhizome, 45g of dried ginger and 5g of monkshood are weighed respectively and added into a traditional Chinese medicine decocting tank together. 1400ml of water is added into the decocting pot to soak the traditional Chinese medicine raw materials for 30 min. Then heating the decocting pot with strong fire until boiling in the decocting pot, adjusting to small fire, and keeping the heating temperature at 100-. Turning off the fire, filtering the solid-liquid mixture in the decocting pot, and removing the residue to obtain 600ml of decoction.
Example 5
A traditional Chinese medicine composition for treating deficiency-cold is prepared from the following traditional Chinese medicine raw materials in parts by weight: 50g of poria cocos, 50g of bighead atractylodes rhizome, 15g of dried ginger and 10g of aconite.
During preparation, 50g of poria cocos, 50g of bighead atractylodes rhizome, 15g of dried ginger and 10g of aconite root are respectively weighed and added into a traditional Chinese medicine decocting tank together. 1300ml of water is added into the decocting pot to soak the traditional Chinese medicine raw materials for 40 min. Then heating the decocting pot with strong fire until boiling in the decocting pot, adjusting to small fire, and keeping the heating temperature at 100-. Turning off the fire, filtering the solid-liquid mixture in the decocting pot, and removing the residue to obtain 550ml of decoction.
Examples of the experiments
Subject: 393 patients in total, 98 male patients and 295 female patients, wherein the age is 50-85 years old, all patients have joint and muscle pain caused by invasion of wind-cold-dampness pathogen due to deficiency-cold, and the clinical manifestations of the disease are cold, aversion to cold, heavy body, pain or slight swelling, cold hands and feet, poor sleep, sleepiness, depression, pain in abdomen with diarrhea, oliguria or frequent micturition, pale tongue, and slippery teeth-mark.
The treatment mode comprises the following steps: the Chinese medicinal composition juice in the scheme is taken three times in the morning, at noon and at night, 200ml of the Chinese medicinal composition juice is taken every time, one week is taken, and clinical curative effect observation is carried out.
The judgment standard of the curative effect is as follows: 1) cure, complete disappearance of symptoms and signs; 2) the effect is obvious, most symptoms and signs disappear after treatment; 3) there was no relief or even a tendency for symptoms and signs to worsen.
And (3) counting the curative effect: according to statistics, 187 cured patients, 167 effective patients and 39 ineffective patients in all experimental patients, and the total effective rate is 90.0%.
Therefore, the traditional Chinese medicine composition in the scheme has a remarkable curative effect in the aspect of curing or relieving related diseases caused by deficiency-cold under the mutual matching and synergistic effect of the specifically compatible traditional Chinese medicine components, and is suitable for clinical popularization and application.
The above description is only an embodiment of the present invention, and not intended to limit the scope of the present invention, and all equivalent flow transformations made by the present specification, or directly or indirectly applied to other related technical fields, are included in the scope of the present invention.
Claims (8)
- A traditional Chinese medicine composition for treating deficiency-cold is characterized by being prepared from the following traditional Chinese medicine raw materials in parts by weight: 10-50 parts of poria cocos, 10-50 parts of bighead atractylodes rhizome, 15-75 parts of dried ginger and 5-15 parts of monkshood.
- The traditional Chinese medicine composition as claimed in claim 1, which is prepared from the following traditional Chinese medicine raw materials in parts by weight: 45 parts of poria cocos, 30 parts of bighead atractylodes rhizome, 45 parts of dried ginger and 5-15 parts of monkshood.
- The traditional Chinese medicine composition as claimed in claim 1, which is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10-50 parts of poria cocos, 40-50 parts of bighead atractylodes rhizome, 15-75 parts of dried ginger and 5-15 parts of monkshood.
- The traditional Chinese medicine composition as claimed in claim 3, which is prepared from the following traditional Chinese medicine raw materials in parts by weight: 45 parts of poria cocos, 45 parts of bighead atractylodes rhizome, 45 parts of dried ginger and 5-15 parts of monkshood.
- A method for preparing the Chinese medicinal composition as claimed in any one of claims 1 to 4, comprising the steps of:s1, mixing, namely weighing the traditional Chinese medicine raw materials of poria cocos, bighead atractylodes rhizome, dried ginger and monkshood according to the mixture ratio;s2, soaking, namely soaking the weighed traditional Chinese medicine raw materials in water;s3, decocting, heating and decocting the soaked traditional Chinese medicine raw materials;s4, filtering, and filtering after the decoction is finished to remove the dregs of a decoction to obtain the decoction.
- The method of claim 5, wherein: in the step of S2 soaking, water is added according to the amount 9-11 times of the total weight of the traditional Chinese medicine raw materials, and the traditional Chinese medicine raw materials are soaked for 20-40 min.
- The method of claim 5, wherein: in the S3 decocting step, the mixture is heated to boiling and then continuously decocted for 90-120min at the temperature of 100-115 ℃.
- The method of claim 5, wherein: in the step S4, the volume of the finally obtained medicine juice is 3/8-1/2 of the volume corresponding to the added water volume.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2018/117740 WO2020107228A1 (en) | 2018-11-27 | 2018-11-27 | Traditional chinese medicine composition capable of treating asthenia cold and preparation method therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111601612A true CN111601612A (en) | 2020-08-28 |
Family
ID=70852472
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201880028270.XA Pending CN111601612A (en) | 2018-11-27 | 2018-11-27 | A Chinese medicinal composition for treating deficiency cold, and its preparation method |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN111601612A (en) |
| WO (1) | WO2020107228A1 (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102847098A (en) * | 2012-07-19 | 2013-01-02 | 李承平 | Tablet for warming middle energizer and dispelling cold |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101366941B (en) * | 2008-10-07 | 2012-02-22 | 梁邦山 | Traditional Chinese medicine capsule for treating cold symptoms type nephritis |
-
2018
- 2018-11-27 CN CN201880028270.XA patent/CN111601612A/en active Pending
- 2018-11-27 WO PCT/CN2018/117740 patent/WO2020107228A1/en active Application Filing
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102847098A (en) * | 2012-07-19 | 2013-01-02 | 李承平 | Tablet for warming middle energizer and dispelling cold |
Non-Patent Citations (3)
| Title |
|---|
| 叶进: "经方中白术的配伍规律探析", 《中国中医基础医学杂志》 * |
| 王彩霞等: "理脾阴正方提高Alzheimer痴呆小鼠抗氧化酶活性的研究", 《中医药学刊》 * |
| 韦桂宁、李敏: "《图解温病条辨》", 31 January 2018 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020107228A1 (en) | 2020-06-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103272169B (en) | Application of rhodiola rosea compound composite in treating erosive gastritis | |
| CN102091282B (en) | Medicament for treating chronic gastritis and gastric ulcer | |
| CN103285310B (en) | Use of rhodiola rosea compound composition in preparing medicine for curing gastric ulcer | |
| CN103285309B (en) | Rhodiola rosea compound composition for treating peptic ulcer | |
| CN101972443B (en) | Chinese medicinal formula for treating chronic gastritis | |
| CN103272170B (en) | Application of rhodiola rosea compound composite in preparing drug for treating duodenal ulcer | |
| CN102614451B (en) | Traditional Chinese medicine for warming channel to expelling cold, warming stomach to stop vomiting and removing dampness for improvement | |
| CN111491653A (en) | Traditional Chinese medicine composition and preparation method and application thereof | |
| CN103142820B (en) | Health care wine for treating hyposexuality, impotence and premature ejaculation | |
| CN103463588B (en) | A kind of Chinese medicine composition for the treatment of sinking of QI of middle-JIAO | |
| CN102139032B (en) | Traditional Chinese medicine for treating intervertebral disc protrusion, hyperosteogeny and rheumatoid disease | |
| CN104474108A (en) | Traditional Chinese medicine preparation for treating acute appendicitis and preparation method of traditional Chinese medicine preparation | |
| CN111601612A (en) | A Chinese medicinal composition for treating deficiency cold, and its preparation method | |
| CN104306595A (en) | Traditional Chinese medicine preparation for heel pain and preparation method thereof | |
| CN104013897A (en) | Traditional Chinese medicine composition for treating dysmenorrheal and preparation method of traditional Chinese medicine composition | |
| CN104435560A (en) | Traditional Chinese medicine composition for relieving wound pain after wear-off of anesthetic and preparation method of traditional Chinese medicine composition | |
| CN102895450B (en) | External Chinese herbal preparation for treating angiitis fester and gangrene and method for preparing external Chinese herbal preparation for treating angiitis fester and gangrene | |
| CN106310152A (en) | Chinese medicinal composition for treatment of alopecia | |
| CN106074934A (en) | A kind of dispelling wind and removing obstruction in the collateral Antalgica wine and preparation method thereof | |
| CN111629744A (en) | Traditional Chinese medicine composition and preparation method and application thereof | |
| CN105521144A (en) | Impotence treating drug | |
| CN104324318B (en) | A kind of outer wiping analgesic drug product and its preparation application method | |
| CN104324175A (en) | Internal medicine for treating vocal cord polyp and preparation method thereof | |
| CN104758673A (en) | Traditional Chinese medicine composition for treating sequelae of apoplexy | |
| CN104606453A (en) | Traditional Chinese medicine composition for treating lumbago due to kidney deficiency |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20200828 |
|
| RJ01 | Rejection of invention patent application after publication |