CN111567808A - Probiotic composition - Google Patents
Probiotic composition Download PDFInfo
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- CN111567808A CN111567808A CN202010451642.9A CN202010451642A CN111567808A CN 111567808 A CN111567808 A CN 111567808A CN 202010451642 A CN202010451642 A CN 202010451642A CN 111567808 A CN111567808 A CN 111567808A
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- 239000006041 probiotic Substances 0.000 title claims abstract description 72
- 235000018291 probiotics Nutrition 0.000 title claims abstract description 72
- 239000000203 mixture Substances 0.000 title claims abstract description 66
- 230000000529 probiotic effect Effects 0.000 title claims abstract description 61
- 239000011573 trace mineral Substances 0.000 claims abstract description 31
- 235000013619 trace mineral Nutrition 0.000 claims abstract description 31
- 238000002360 preparation method Methods 0.000 claims abstract description 27
- 229910052500 inorganic mineral Inorganic materials 0.000 claims abstract description 22
- 235000010755 mineral Nutrition 0.000 claims abstract description 22
- 239000011707 mineral Substances 0.000 claims abstract description 22
- 241000186660 Lactobacillus Species 0.000 claims abstract description 20
- 210000001156 gastric mucosa Anatomy 0.000 claims abstract description 20
- 229940039696 lactobacillus Drugs 0.000 claims abstract description 20
- 239000000843 powder Substances 0.000 claims abstract description 20
- 229940107518 slippery elm bark Drugs 0.000 claims abstract description 20
- 230000008439 repair process Effects 0.000 claims abstract description 19
- 229940069521 aloe extract Drugs 0.000 claims abstract description 18
- 239000008213 purified water Substances 0.000 claims abstract description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 15
- 239000007788 liquid Substances 0.000 claims abstract description 13
- 239000000654 additive Substances 0.000 claims abstract description 11
- 230000000996 additive effect Effects 0.000 claims abstract description 11
- 239000002994 raw material Substances 0.000 claims abstract description 9
- 238000002156 mixing Methods 0.000 claims description 61
- 238000010438 heat treatment Methods 0.000 claims description 24
- 238000012545 processing Methods 0.000 claims description 21
- 239000000126 substance Substances 0.000 claims description 21
- 238000003756 stirring Methods 0.000 claims description 20
- 238000001816 cooling Methods 0.000 claims description 19
- 238000005096 rolling process Methods 0.000 claims description 18
- 239000011259 mixed solution Substances 0.000 claims description 14
- 238000001914 filtration Methods 0.000 claims description 13
- 241000193830 Bacillus <bacterium> Species 0.000 claims description 12
- 238000004519 manufacturing process Methods 0.000 claims description 12
- 241000235342 Saccharomycetes Species 0.000 claims description 10
- 238000001035 drying Methods 0.000 claims description 6
- 238000001291 vacuum drying Methods 0.000 claims description 6
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 claims description 2
- 241001116389 Aloe Species 0.000 claims description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 claims description 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims description 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 2
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims description 2
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 2
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims description 2
- PWHULOQIROXLJO-UHFFFAOYSA-N Manganese Chemical compound [Mn] PWHULOQIROXLJO-UHFFFAOYSA-N 0.000 claims description 2
- 229930195725 Mannitol Natural products 0.000 claims description 2
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 claims description 2
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims description 2
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims description 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims description 2
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims description 2
- 235000011399 aloe vera Nutrition 0.000 claims description 2
- 239000011575 calcium Substances 0.000 claims description 2
- 229910052791 calcium Inorganic materials 0.000 claims description 2
- 239000000460 chlorine Substances 0.000 claims description 2
- 229910052801 chlorine Inorganic materials 0.000 claims description 2
- 239000010941 cobalt Substances 0.000 claims description 2
- 229910017052 cobalt Inorganic materials 0.000 claims description 2
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 claims description 2
- 229910052802 copper Inorganic materials 0.000 claims description 2
- 239000010949 copper Substances 0.000 claims description 2
- 239000011737 fluorine Substances 0.000 claims description 2
- 229910052731 fluorine Inorganic materials 0.000 claims description 2
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 2
- 238000000227 grinding Methods 0.000 claims description 2
- 239000003485 histamine H2 receptor antagonist Substances 0.000 claims description 2
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 claims description 2
- 239000000832 lactitol Substances 0.000 claims description 2
- 235000010448 lactitol Nutrition 0.000 claims description 2
- VQHSOMBJVWLPSR-JVCRWLNRSA-N lactitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-JVCRWLNRSA-N 0.000 claims description 2
- 229960003451 lactitol Drugs 0.000 claims description 2
- 239000011777 magnesium Substances 0.000 claims description 2
- 229910052749 magnesium Inorganic materials 0.000 claims description 2
- 229910052748 manganese Inorganic materials 0.000 claims description 2
- 239000011572 manganese Substances 0.000 claims description 2
- 239000000594 mannitol Substances 0.000 claims description 2
- 235000010355 mannitol Nutrition 0.000 claims description 2
- 231100000252 nontoxic Toxicity 0.000 claims description 2
- 230000003000 nontoxic effect Effects 0.000 claims description 2
- 239000011574 phosphorus Substances 0.000 claims description 2
- 229910052698 phosphorus Inorganic materials 0.000 claims description 2
- 239000011591 potassium Substances 0.000 claims description 2
- 229910052700 potassium Inorganic materials 0.000 claims description 2
- 229940126409 proton pump inhibitor Drugs 0.000 claims description 2
- 239000000612 proton pump inhibitor Substances 0.000 claims description 2
- 239000010703 silicon Substances 0.000 claims description 2
- 229910052710 silicon Inorganic materials 0.000 claims description 2
- 239000011734 sodium Substances 0.000 claims description 2
- 229910052708 sodium Inorganic materials 0.000 claims description 2
- 239000000600 sorbitol Substances 0.000 claims description 2
- 235000010356 sorbitol Nutrition 0.000 claims description 2
- 239000011593 sulfur Substances 0.000 claims description 2
- 229910052717 sulfur Inorganic materials 0.000 claims description 2
- 239000011701 zinc Substances 0.000 claims description 2
- 229910052725 zinc Inorganic materials 0.000 claims description 2
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract description 10
- 230000001502 supplementing effect Effects 0.000 abstract description 5
- 241000894006 Bacteria Species 0.000 abstract description 3
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract description 3
- 230000006872 improvement Effects 0.000 description 8
- 239000003814 drug Substances 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 244000005700 microbiome Species 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 239000003223 protective agent Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/14—Yeasts or derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D29/00—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor
- B01D29/01—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with flat filtering elements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/20—Measuring; Control or regulation
- B01F35/22—Control or regulation
- B01F35/221—Control or regulation of operational parameters, e.g. level of material in the mixer, temperature or pressure
- B01F35/2214—Speed during the operation
- B01F35/22142—Speed of the mixing device during the operation
- B01F35/221422—Speed of rotation of the mixing axis, stirrer or receptacle during the operation
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
Abstract
The invention provides a probiotic composition, which comprises the following raw materials in percentage by mass: 5.0 to 8.0 percent of yeast, 5.0 to 7.0 percent of probiotic spore, 4.0 to 7.0 percent of lactobacillus, 3.0 to 5.0 percent of trace mineral, 2.0 to 5.0 percent of edible mineral, 2.0 to 4.0 percent of aloe extract, 2.0 to 4.0 percent of slippery elm bark powder, 1.0 to 3.0 percent of additive, 1.0 to 2.0 percent of gastric mucosa repair preparation and the balance of purified water, wherein the components of the probiotic composition are added with various probiotic bacteria such as yeast, probiotic spore, lactobacillus and the like and are added with a plurality of groups of elements required by human bodies such as trace mineral and edible mineral, so as to achieve the purpose of supplementing trace elements for human bodies, and in addition, the aloe extract, slippery elm bark powder and gastric mucosa repair preparation are added into the composition, so that the damaged parts of intestinal tracts of human bodies can be repaired and maintained while the oral liquid of the probiotic composition is taken, improving the integrity of human intestinal tract.
Description
Technical Field
The invention relates to the technical field of probiotics, in particular to a probiotic composition.
Background
Probiotics are active microorganisms which are beneficial to a host and change the composition of flora at a certain part of the host by colonizing in a human body. The health-care composition has the advantages that the health-care composition can promote nutrition absorption to keep intestinal tract healthy by adjusting the host mucous membrane and the system immunologic function or adjusting the balance of flora in the intestinal tract, so that single microorganisms or mixed microorganisms with definite composition favorable for health are generated, probiotics are gradually used in the field of medicaments along with the development of science and technology, probiotics and trace elements in the human body can be supplemented, and the intestinal tract health of users is effectively improved.
The existing oral liquid of the probiotic composition has the following problems in the process of taking: (1) although the existing probiotic composition for oral administration contains probiotic bacteria, the types of the probiotic bacteria are single, components for repairing and protecting human intestinal tracts are lacked, and the medicinal effect is poor; (2) the existing probiotic composition processing and mixing mode usually adopts a simple stirring and mixing mode, so that all components cannot be fully fused, and the drug effect is influenced.
Disclosure of Invention
In view of the above defects, the present invention aims to provide a probiotic composition, which is prepared by adding various trace elements and a composition having intestinal tract repair and maintenance functions, and improving the preparation process, so as to obtain a product having the functions of repairing, maintaining and promoting digestion of intestinal tract.
The invention is realized by the following technical scheme:
the probiotic composition comprises the following raw materials in percentage by mass: 5.0 to 8.0 percent of microzyme, 5.0 to 7.0 percent of probiotic spore, 4.0 to 7.0 percent of lactobacillus, 3.0 to 5.0 percent of trace mineral, 2.0 to 5.0 percent of edible mineral, 2.0 to 4.0 percent of aloe extract, 2.0 to 4.0 percent of slippery elm bark powder, 1.0 to 3.0 percent of additive, 1.0 to 2.0 percent of gastric mucosa repair preparation and the balance of purified water.
As an improvement of the technical scheme, the material comprises the following raw materials in percentage by mass: 7.0% of microzyme, 6.0% of probiotic bacillus, 5.0% of lactobacillus, 4.0% of trace mineral, 4.0% of edible mineral, 3.0% of aloe extract, 3.0% of slippery elm bark powder, 2.0% of additive, 1.0% of gastric mucosa repair preparation and the balance of purified water.
As an improvement of the technical scheme, the trace mineral comprises three or more trace elements of zinc, copper, iodine, cobalt, manganese and fluorine.
As an improvement of the technical scheme, the edible mineral substances comprise three or more of sodium, potassium, calcium, magnesium, iron, sulfur, phosphorus, silicon, chlorine, chloride and acetate.
As an improvement of the technical scheme, the aloe extract is non-toxic aloe juice.
As an improvement of the above technical solution, the additive comprises one or more of mannitol, sorbitol and lactitol.
As an improvement of the technical scheme, the gastric mucosa repair preparation adopts one or more of a proton pump inhibitor, an H2 receptor antagonist and a gastric mucosa protective agent.
The probiotic composition also comprises a preparation method of the composition, and the preparation method comprises the following steps:
step 1: proportioning and premixing treatment: sequentially adding saccharomycetes, probiotic bacillus, lactobacillus, trace mineral substances, edible mineral substances and purified water into a mixing container according to the proportion for premixing, heating, stirring and mixing, wherein the heating temperature of the mixing container is 20-30 ℃, the rotating speed of a stirring rod is 150-280 revolutions per minute, the mixing time is 30-50 minutes, standing is carried out for 20-30 minutes, and aloe extract, slippery elm bark powder and gastric mucosa repair preparation are filled into the mixing container for secondary mixing, the heating temperature of the mixing container is 20-40 ℃, the rotating speed of the stirring rod is 200-300 revolutions per minute, and the mixing time is 30-40 minutes, so that the mixed solution in the mixing container is mixed into a transparent state;
step 2: processing and cooling treatment: the mixed solution is contained in a sealed container and is placed in a cooling chamber for cooling treatment, the indoor temperature is controlled to be 2-5 ℃, and the mixed solution is placed for 1-1.5 hours;
and step 3: and (3) filtering and deep processing treatment: inverting the mixture in a screen with the aperture of 0.8-1.2 mm for filtering treatment, placing the filtered mixture in a rolling type drier for rolling type drying treatment, wherein the heating temperature is 30-50 ℃, the rolling speed is 200-350 r/min, and the mixing time is 1-1.5 h;
and 4, step 4: production and processing: and guiding the mixed liquid into a sealed containing tank body, carrying out bottling treatment through a production line, and carrying out vacuum drying treatment on the outer package of the bottle body after bottling.
As an improvement of the technical scheme, the slippery elm bark powder is taken from the inner 2cm-3cm of slippery elm bark, the inner bark is dried at high temperature, and the dried inner bark is ground into powder by a grinding device.
The invention has the beneficial effects that:
(1) in addition, aloe extract, slippery elm bark powder and gastric mucosa repair preparations are added into the composition, so that the damaged part of the intestinal tract of a human body can be repaired and maintained while the probiotic composition oral liquid is taken, and the integrity of the intestinal tract of the human body is improved.
(2) In the process of processing the probiotic composition, the multi-step stirring, cooling and filtering treatment are adopted, so that the medicine properties of the probiotic composition can be fully fused and the medicine effect can be exerted, and the safety of the probiotic composition can be improved by adopting sealed treatment in the whole processing process.
Detailed Description
Example 1:
the probiotic composition comprises the following raw materials in percentage by mass: 5.0% of microzyme, 5.0% of probiotic bacillus, 4.0% of lactobacillus, 3.0% of trace mineral, 2.0% of edible mineral, 2.0% of aloe extract, 2.0% of slippery elm bark powder, 1.0% of additive, 1.0% of gastric mucosa repair preparation and the balance of purified water.
The probiotic composition also comprises a preparation method of the composition:
step 1: proportioning and premixing treatment: sequentially adding saccharomycetes, probiotic bacillus, lactobacillus, trace mineral substances, edible mineral substances and purified water into a mixing container according to the proportion for premixing, heating, stirring and mixing, wherein the heating temperature of the mixing container is 20 ℃, the rotating speed of a stirring rod is 150 revolutions per minute, the mixing time is 30 minutes, standing is carried out for 20 minutes, and aloe extract, slippery elm bark powder and gastric mucosa repair preparation are poured into the mixing container for secondary mixing, the heating temperature of the mixing container is 20 ℃, the rotating speed of the stirring rod is 200 revolutions per minute, and the mixing time is 30 minutes, so that the internal mixed solution is mixed into a transparent state;
step 2: processing and cooling treatment: the mixed solution is contained in a sealed container and is placed in a cooling chamber for cooling treatment, the indoor temperature is controlled to be 2 ℃, and the mixed solution is placed for 1 hour;
and step 3: and (3) filtering and deep processing treatment: inverting the mixture in a screen with the aperture of 0.8mm for filtering, placing the filtered mixture in a rolling type drier for rolling type drying treatment, wherein the heating temperature is 30 ℃, the rolling speed is 200 r/min, and the mixing time is 1 h;
and 4, step 4: production and processing: and guiding the mixed liquid into a sealed containing tank body, carrying out bottling treatment through a production line, and carrying out vacuum drying treatment on the outer package of the bottle body after bottling.
The invention adds a plurality of probiotics such as saccharomycetes, probiotics spores, lactobacillus and the like into the components of the probiotic composition, and adds a plurality of groups of elements required by human bodies such as trace mineral substances, edible mineral substances and the like, thereby achieving the purpose of supplementing trace elements of the human bodies.
Example 2:
the probiotic composition comprises the following raw materials in percentage by mass: 7.0% of microzyme, 6.0% of probiotic bacillus, 5.0% of lactobacillus, 4.0% of trace mineral, 4.0% of edible mineral, 3.0% of aloe extract, 3.0% of slippery elm bark powder, 2.0% of additive, 1.0% of gastric mucosa repair preparation and the balance of purified water.
The probiotic composition also comprises a preparation method of the composition:
step 1: proportioning and premixing treatment: sequentially adding saccharomycetes, probiotic bacillus, lactobacillus, trace mineral substances, edible mineral substances and purified water into a mixing container according to the proportion for premixing, heating, stirring and mixing, wherein the heating temperature of the mixing container is 25 ℃, the rotating speed of a stirring rod is 220 revolutions per minute, the mixing time is 40 minutes, standing is carried out for 25 minutes, and aloe extract, slippery elm bark powder and gastric mucosa repair preparation are filled into the mixing container for secondary mixing, the heating temperature of the mixing container is 30 ℃, the rotating speed of the stirring rod is 250 revolutions per minute, and the mixing time is 35 minutes, so that the mixed liquid in the mixing container is mixed into a transparent state;
step 2: processing and cooling treatment: the mixed solution is contained in a sealed container and is placed in a cooling chamber for cooling treatment, the indoor temperature is controlled to be 4 ℃, and the mixed solution is placed for 1.2 hours;
and step 3: and (3) filtering and deep processing treatment: inverting the mixture in a screen with the aperture of 1.0mm for filtering, placing the filtered mixture in a rolling type drier for rolling type drying treatment, wherein the heating temperature is 40 ℃, the rolling speed is 280 revolutions per minute, and the mixing time is 1.2 hours;
and 4, step 4: production and processing: and guiding the mixed liquid into a sealed containing tank body, carrying out bottling treatment through a production line, and carrying out vacuum drying treatment on the outer package of the bottle body after bottling.
The invention adds a plurality of probiotics such as saccharomycetes, probiotics spores, lactobacillus and the like into the components of the probiotic composition, and adds a plurality of groups of elements required by human bodies such as trace mineral substances, edible mineral substances and the like, thereby achieving the purpose of supplementing trace elements of the human bodies.
Example 3:
the probiotic composition comprises the following raw materials in percentage by mass: 8.0% of microzyme, 7.0% of probiotic bacillus, 7.0% of lactobacillus, 5.0% of trace mineral, 5.0% of edible mineral, 4.0% of aloe extract, 4.0% of slippery elm bark powder, 3.0% of additive, 2.0% of gastric mucosa repair preparation and the balance of purified water.
The probiotic composition also comprises a preparation method of the composition:
step 1: proportioning and premixing treatment: sequentially adding saccharomycetes, probiotic bacillus, lactobacillus, trace mineral substances, edible mineral substances and purified water into a mixing container according to the proportion for premixing, heating, stirring and mixing, wherein the heating temperature of the mixing container is 30 ℃, the rotating speed of a stirring rod is 280 revolutions per minute, the mixing time is 50 minutes, standing is carried out for 30 minutes, and aloe extract, slippery elm bark powder and gastric mucosa repair preparation are filled into the mixing container for secondary mixing, the heating temperature of the mixing container is 40 ℃, the rotating speed of the stirring rod is 300 revolutions per minute, and the mixing time is 40 minutes, so that the mixed liquid in the mixing container is mixed into a transparent state;
step 2: processing and cooling treatment: the mixed solution is contained in a sealed container and is placed in a cooling chamber for cooling treatment, the indoor temperature is controlled at 5 ℃, and the mixed solution is placed for 1.5 hours;
and step 3: and (3) filtering and deep processing treatment: inverting the mixture in a screen with the aperture of 1.2mm for filtering, placing the filtered mixture in a rolling type drier for rolling type drying treatment, wherein the heating temperature is 50 ℃, the rolling speed is 350 r/min, and the mixing time is 1.5 h;
and 4, step 4: production and processing: and guiding the mixed liquid into a sealed containing tank body, carrying out bottling treatment through a production line, and carrying out vacuum drying treatment on the outer package of the bottle body after bottling.
The invention adds a plurality of probiotics such as saccharomycetes, probiotics spores, lactobacillus and the like into the components of the probiotic composition, and adds a plurality of groups of elements required by human bodies such as trace mineral substances, edible mineral substances and the like, thereby achieving the purpose of supplementing trace elements of the human bodies.
Example 4 (comparative example)
The probiotic composition comprises the following raw materials in percentage by mass: 7.0% of yeast, 6.0% of probiotic bacillus, 5.0% of lactobacillus, 4.0% of trace mineral, 4.0% of edible mineral, 2.0% of additive and the balance of purified water.
The probiotic composition also comprises a preparation method of the composition:
step 1: proportioning and premixing treatment: sequentially adding saccharomycetes, probiotic bacillus, lactobacillus, trace mineral substances, edible mineral substances and purified water into a mixing container according to the proportion for premixing, heating, stirring and mixing, wherein the heating temperature of the mixing container is 25 ℃, the rotating speed of a stirring rod is 220 revolutions per minute, the mixing time is 40 minutes, standing is carried out for 25 minutes, and aloe extract, slippery elm bark powder and gastric mucosa repair preparation are filled into the mixing container for secondary mixing, the heating temperature of the mixing container is 30 ℃, the rotating speed of the stirring rod is 250 revolutions per minute, and the mixing time is 35 minutes, so that the mixed liquid in the mixing container is mixed into a transparent state;
step 2: processing and cooling treatment: the mixed solution is contained in a sealed container and is placed in a cooling chamber for cooling treatment, the indoor temperature is controlled to be 4 ℃, and the mixed solution is placed for 1.2 hours;
and step 3: and (3) filtering and deep processing treatment: inverting the mixture in a screen with the aperture of 1.0mm for filtering, placing the filtered mixture in a rolling type drier for rolling type drying treatment, wherein the heating temperature is 40 ℃, the rolling speed is 280 revolutions per minute, and the mixing time is 1.2 hours;
and 4, step 4: production and processing: and guiding the mixed liquid into a sealed containing tank body, carrying out bottling treatment through a production line, and carrying out vacuum drying treatment on the outer package of the bottle body after bottling.
The invention adds a plurality of probiotics such as saccharomycetes, probiotic spores, lactobacillus and the like into the components of the probiotic composition, and adds a plurality of groups of elements required by human body such as trace mineral substances, edible mineral substances and the like, thereby achieving the purpose of supplementing trace elements for human body.
Specifically, the administration effects of the probiotic compositions of examples 1-4 were tested in 80 human subjects with intestinal dyspepsia.
In addition, the comparison parameters show that the probiotic composition can more easily exert the drug property in the probiotic composition, so as to achieve better treatment effect.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that changes may be made in the embodiments and/or equivalents thereof without departing from the spirit and scope of the invention. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (9)
1. A probiotic composition characterized by: comprises the following raw materials in percentage by mass: 5.0 to 8.0 percent of microzyme, 5.0 to 7.0 percent of probiotic spore, 4.0 to 7.0 percent of lactobacillus, 3.0 to 5.0 percent of trace mineral, 2.0 to 5.0 percent of edible mineral, 2.0 to 4.0 percent of aloe extract, 2.0 to 4.0 percent of slippery elm bark powder, 1.0 to 3.0 percent of additive, 1.0 to 2.0 percent of gastric mucosa repair preparation and the balance of purified water.
2. The probiotic composition according to claim 1, characterized in that: comprises the following raw materials in percentage by mass: 7.0% of microzyme, 6.0% of probiotic bacillus, 5.0% of lactobacillus, 4.0% of trace mineral, 4.0% of edible mineral, 3.0% of aloe extract, 3.0% of slippery elm bark powder, 2.0% of additive, 1.0% of gastric mucosa repair preparation and the balance of purified water.
3. The probiotic composition according to claim 1, characterized in that: the trace mineral comprises three or more trace elements of zinc, copper, iodine, cobalt, manganese and fluorine.
4. The probiotic composition according to claim 1, characterized in that: the edible mineral comprises three or more of sodium, potassium, calcium, magnesium, ferrum, sulfur, phosphorus, silicon, chlorine, chloride and acetate.
5. The probiotic composition according to claim 1, characterized in that: the aloe extract is nontoxic aloe juice.
6. The probiotic composition according to claim 1, characterized in that: the additive comprises one or more of mannitol, sorbitol and lactitol.
7. The probiotic composition according to claim 1, characterized in that: the gastric mucosa repair preparation employs one or more of a proton pump inhibitor, an H2 receptor antagonist and a gastric mucosa protectant.
8. The probiotic composition according to claim 1, characterized in that: the probiotic composition also comprises a preparation method of the composition, and the preparation method comprises the following steps:
step 1: proportioning and premixing treatment: sequentially adding saccharomycetes, probiotic bacillus, lactobacillus, trace mineral substances, edible mineral substances and purified water into a mixing container according to the proportion for premixing, heating, stirring and mixing, wherein the heating temperature of the mixing container is 20-30 ℃, the rotating speed of a stirring rod is 150-280 revolutions per minute, the mixing time is 30-50 minutes, standing is carried out for 20-30 minutes, and aloe extract, slippery elm bark powder and gastric mucosa repair preparation are filled into the mixing container for secondary mixing, the heating temperature of the mixing container is 20-40 ℃, the rotating speed of the stirring rod is 200-300 revolutions per minute, and the mixing time is 30-40 minutes, so that the mixed liquid in the mixing container is mixed into a transparent state;
step 2: processing and cooling treatment: the mixed solution is contained in a sealed container and is placed in a cooling chamber for cooling treatment, the indoor temperature is controlled to be 2-5 ℃, and the mixed solution is placed for 1-1.5 hours;
and step 3: and (3) filtering and deep processing treatment: inverting the mixture in a screen with the aperture of 0.8mm-1.2mm for filtering treatment, placing the filtered mixture in a rolling type drier for rolling type drying treatment, wherein the heating temperature is 30-50 ℃, the rolling speed is 200-350 r/min, and the mixing time is 1-1.5 h;
and 4, step 4: production and processing: and guiding the mixed liquid into a sealed containing tank body, carrying out bottling treatment through a production line, and carrying out vacuum drying treatment on the outer package of the bottle body after bottling.
9. The probiotic composition according to claim 8, characterized in that: the slippery elm bark powder is taken from the inner skin of the slippery elm bark with the length of 2cm-3cm, the inner skin is dried at high temperature, and the dried inner skin is ground into powder by a grinding device.
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| CN113261675A (en) * | 2021-06-02 | 2021-08-17 | 河北源民生物科技有限公司 | Probiotic composition suitable for human immunity |
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Application publication date: 20200825 |