CN111544354A - 一种皮肤抑菌私处护理液及其制备方法 - Google Patents
一种皮肤抑菌私处护理液及其制备方法 Download PDFInfo
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- MCSINKKTEDDPNK-UHFFFAOYSA-N propyl propionate Chemical compound CCCOC(=O)CC MCSINKKTEDDPNK-UHFFFAOYSA-N 0.000 claims abstract description 28
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- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims abstract description 19
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Abstract
本发明提供一种皮肤抑菌私处护理液，按重量份数计，由以下原料制备而成：聚六亚甲基胍0.01‑0.1份、醋酸氯己定0.05‑0.5份、薄荷醇0.01‑0.5份、椰油基甘油酯0.02‑0.5份、胶原蛋白0.01‑0.1份、尿囊素0.1‑0.5份、洋甘菊0.1‑0.5份、甘油2.0‑8.0份、乙醇1.0‑75份、纯化水25‑98份。本发明提供一种稳定性高、储存方便的、抑菌效果好的皮肤抑菌私处护理液及其制备方法。
Description
技术领域
本发明涉及卫生保健及医药保健外用液剂，特别涉及一种皮肤抑菌私处护理液及其制备方法。
背景技术
目前，市场上很多种适用于男女性私处用的抑菌护理液，它们一般都具有清洁男女性私处、防治细菌感染等功效。然而，这些护理液中大多主要抗菌成分是醋酸氯己定，醋酸氯已定具有抗菌谱广、抗菌作用较强的特点，对革兰阳性菌及革兰阴性菌均有效，但是现有的护理液中醋酸氯己定中的稳定性不高，大多数情况适宜在低温的状态下进行储存，并且醋酸氯己定遇阴离子表面活性剂易发生反应失去抗菌活性。
因此，需要设计一种稳定性高、储存方便的、抑菌效果好的皮肤抑菌私处护理液及其制备方法。
发明内容
本发明的目的在于提供一种稳定性高、储存方便的、抑菌效果好的皮肤抑菌私处护理液及其制备方法。
本发明的上述技术目的是通过以下技术方案得以实现的：
一种皮肤抑菌私处护理液，按重量份数计，由以下原料制备而成：聚六亚甲基胍0.01-0.1份、醋酸氯己定0.05-0.5份、薄荷醇0.01-0.5份、椰油基甘油酯0.02-0.5份、胶原蛋白0.01-0.1份、尿囊素0.1-0.5份、洋甘菊0.1-0.5份、甘油2.0-8.0份、乙醇1.0-75份、纯化水25-98份。
作为本发明的进一步设置，还包括香精1-10份。
作为本发明的进一步设置，按重量份数计，由以下原料制备而成：聚六亚甲基胍0.05份、醋酸氯己定0.2份、薄荷醇0.2份、椰油基甘油酯0.2份、胶原蛋白0.5份、尿囊素0.2份、洋甘菊0.2份、甘油6.0份、乙醇50份、纯化水50份、香精5份。
还提供一种皮肤抑菌私处护理液的制备方法，包括以下步骤：
步骤S1：称取醋酸氯己定、尿囊素、洋甘菊、薄荷醇、胶原蛋白，精密称定，备用；
步骤S2：量取甘油、乙醇、椰油基甘油酯、聚六亚甲基胍、香精，备用；
步骤S3：取纯净水适量，加入尿囊素、洋甘菊、胶原蛋白、甘油，搅拌溶解至完全，备用；
步骤S4：用乙醇溶解醋酸氯己定、薄荷醇，依次加入香精、椰油基甘油酯、聚六亚甲基胍，搅拌均匀，备用；
步骤S5：合并所有备用物料，搅拌均匀；
步骤S6：加纯净水至需要量，过滤，分装。
本发明的有益效果是：
1.本发明中采用聚六亚甲基胍与醋酸氯己定形成复合配方，其相互之间互相作用，协同增效，提高皮肤私处护理液的抑菌杀菌能力，并且聚六亚甲基胍的胍基能与醋酸氯己定相作用，提高醋酸氯己定的耐温度变化的能力，而且提高了醋酸氯己定的表面活性剂的耐受能力，有效提高本护理液的储存稳定性。
2.本发明的在聚六亚甲基胍与醋酸氯己定的基础上，还复配有薄荷醇、洋甘菊，能对私处进行清凉、消炎、舒缓炎症影响，提高本护理液对私处的护理保健作用。
3.本发明还添加有椰油基甘油酯、胶原蛋白和尿囊素，能使得本皮肤护理液在抑菌的效果之上能对私处的皮肤进行护理、保湿，并且有效修复炎症对私处皮肤的破坏，同时降低醋酸氯己定对私处菌群结构的影响及对皮肤细胞的损害作用，有效保护私处的菌群平衡、及时修复受损皮肤细胞，改善私处皮肤状态。
具体实施方式
下面将结合具体实施例对本发明的技术方案进行清楚、完整地描述。显然，所描述的实施例仅仅是本发明的一部分实施例，而不是全部的实施例。基于本发明的实施例，本领域普通技术人员在没有作出创造性劳动前提下所获得的所有其他实施例，都属于本发明保护的范围。
一、实施例
实施例1
一种皮肤抑菌私处护理液，按重量份数计，由以下原料制备而成：聚六亚甲基胍0.01-0.1份、醋酸氯己定0.05份、薄荷醇0.01份、椰油基甘油酯0.02份、胶原蛋白0.01份、尿囊素0.1份、洋甘菊0.1份、甘油2.0份、乙醇1.0份、纯化水25份、香精1份。
还提供一种皮肤抑菌私处护理液的制备方法，包括以下步骤：
步骤S1：称取0.05份醋酸氯己定、0.1份尿囊素、0.1份洋甘菊、0.01份薄荷醇、0.01份胶原蛋白，精密称定，备用；
步骤S2：量取2.0份甘油、1.0份乙醇、0.02份椰油基甘油酯、0.01份聚六亚甲基胍、1-10份香精，备用；
步骤S3：取纯净水适量，加入尿囊素、洋甘菊、胶原蛋白、甘油，搅拌溶解至完全，备用；
步骤S4：用乙醇溶解醋酸氯己定、薄荷醇，依次加入香精、椰油基甘油酯、聚六亚甲基胍，搅拌均匀，备用；
步骤S5：合并所有备用物料，搅拌均匀；
步骤S6：加纯净水至需要量，过滤，分装。
实施例2
一种皮肤抑菌私处护理液，按重量份数计，由以下原料制备而成：聚六亚甲基胍0.1份、醋酸氯己定0.5份、薄荷醇0.5份、椰油基甘油酯0.5份、胶原蛋白0.1份、尿囊素0.5份、洋甘菊0.5份、甘油8.0份、乙醇75份、纯化水98份、香精10份。
还提供一种皮肤抑菌私处护理液的制备方法，包括以下步骤：
步骤S1：称取0.5份醋酸氯己定、0.5份尿囊素、0.5份洋甘菊、0.5份薄荷醇、0.1份胶原蛋白，精密称定，备用；
步骤S2：量取8.0份甘油、75份乙醇、0.5份椰油基甘油酯、0.1份聚六亚甲基胍、10份香精，备用；
步骤S3：取纯净水适量，加入尿囊素、洋甘菊、胶原蛋白、甘油，搅拌溶解至完全，备用；
步骤S4：用乙醇溶解醋酸氯己定、薄荷醇，依次加入香精、椰油基甘油酯、聚六亚甲基胍，搅拌均匀，备用；
步骤S5：合并所有备用物料，搅拌均匀；
步骤S6：加纯净水至需要量，过滤，分装。
实施例3
一种皮肤抑菌私处护理液，按重量份数计，由以下原料制备而成：聚六亚甲基胍0.05份、醋酸氯己定0.2份、薄荷醇0.2份、椰油基甘油酯0.2份、胶原蛋白0.5份、尿囊素0.2份、洋甘菊0.2份、甘油6.0份、乙醇50份、纯化水50份、香精5份。
还提供一种皮肤抑菌私处护理液的制备方法，包括以下步骤：
步骤S1：称取0.2份醋酸氯己定、0.2份尿囊素、0.2份洋甘菊、0.2份薄荷醇、0.5份胶原蛋白，精密称定，备用；
步骤S2：量取6.0份甘油、50份乙醇、0.2份椰油基甘油酯、0.05份聚六亚甲基胍、5份香精，备用；
步骤S3：取纯净水适量，加入尿囊素、洋甘菊、胶原蛋白、甘油，搅拌溶解至完全，备用；
步骤S4：用乙醇溶解醋酸氯己定、薄荷醇，依次加入香精、椰油基甘油酯、聚六亚甲基胍，搅拌均匀，备用；
步骤S5：合并所有备用物料，搅拌均匀；
步骤S6：加纯净水至需要量，过滤，分装。
Claims (4)
1.一种皮肤抑菌私处护理液，其特征在于，按重量份数计，由以下原料制备而成：聚六亚甲基胍0.01-0.1份、醋酸氯己定0.05-0.5份、薄荷醇0.01-0.5份、椰油基甘油酯0.02-0.5份、胶原蛋白0.01-0.1份、尿囊素0.1-0.5份、洋甘菊0.1-0.5份、甘油2.0-8.0份、乙醇1.0-75份、纯化水25-98份。
2.根据权利要求1所述的皮肤抑菌私处护理液，其特征在于，还包括香精1-10份。
3.根据权利要求2所述的皮肤抑菌私处护理液，其特征在于，按重量份数计，由以下原料制备而成：聚六亚甲基胍0.05份、醋酸氯己定0.2份、薄荷醇0.2份、椰油基甘油酯0.2份、胶原蛋白0.5份、尿囊素0.2份、洋甘菊0.2份、甘油6.0份、乙醇50份、纯化水50份、香精5份。
4.一种根据权利要求1-3任一所述的皮肤抑菌私处护理液的制备方法，其特征在于，包括以下步骤：
步骤S1：称取醋酸氯己定、尿囊素、洋甘菊、薄荷醇、胶原蛋白，精密称定，备用；
步骤S2：量取甘油、乙醇、椰油基甘油酯、聚六亚甲基胍、香精，备用；
步骤S3：取纯净水适量，加入尿囊素、洋甘菊、胶原蛋白、甘油，搅拌溶解至完全，备用；
步骤S4：用乙醇溶解醋酸氯己定、薄荷醇，依次加入香精、椰油基甘油酯、聚六亚甲基胍，搅拌均匀，备用；
步骤S5：合并所有备用物料，搅拌均匀；
步骤S6：加纯净水至需要量，过滤，分装。
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