CN111529609A - Traditional Chinese medicine composition, preparation method thereof, external medicine and application thereof - Google Patents

Traditional Chinese medicine composition, preparation method thereof, external medicine and application thereof Download PDF

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CN111529609A
CN111529609A CN202010607644.2A CN202010607644A CN111529609A CN 111529609 A CN111529609 A CN 111529609A CN 202010607644 A CN202010607644 A CN 202010607644A CN 111529609 A CN111529609 A CN 111529609A
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姜国旗
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
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    • A61K36/484Glycyrrhiza (licorice)
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    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
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    • A61K36/88Liliopsida (monocotyledons)
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    • A61K2236/35Extraction with lipophilic solvents, e.g. Hexane or petrol ether

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Abstract

The invention relates to the field of medicines, and particularly discloses a traditional Chinese medicine composition and a preparation method thereof, an external medicine and application thereof, wherein the traditional Chinese medicine composition comprises the following raw materials: radix rehmanniae, radix et rhizoma Rhei, Notopterygii rhizoma, radix Angelicae Dahuricae, sanguis Draxonis, Carthami flos, fructus forsythiae, Glycyrrhrizae radix and Borneolum Syntheticum. The traditional Chinese medicine composition provided by the invention is a pure traditional Chinese medicine for external use, has no toxic or side effect, has excellent treatment effect on bone injury and bone disease through reasonable compatibility of various raw materials, is suitable for various fractures and dislocation, and various bone injury and bone disease such as neck, shoulder, waist and leg pain, tenosynovitis, cervical, thoracic and lumbar hyperplasia and protrusion.

Description

Traditional Chinese medicine composition, preparation method thereof, external medicine and application thereof
Technical Field
The invention relates to the field of medicines, in particular to a traditional Chinese medicine composition, a preparation method thereof, an external medicine and application thereof.
Background
With the continuous acceleration of life rhythm, various bone injuries and bone diseases are more and more problematic. For example, various fracture and dislocation problems, cervical spondylosis, hyperplasia of cervical vertebra, thoracic vertebra and lumbar vertebra, protrusion and the like all have adverse effects on the life and daily work of people, so that not only the patients feel pain, but also the movement is inconvenient, and even normal life cannot be carried out.
At present, the main methods for treating various bone injuries and bone diseases comprise: medication, surgery, and other ancillary physical therapies. The medicine treatment is still the basis for treating various bone injuries and bone diseases, most of the medicines for treating various bone injuries and bone diseases are western medicines, and have large toxic and side effects, and some traditional Chinese medicines can reduce the toxic and side effects. However, because the medicines are all orally taken, certain toxic and side effects still exist, and particularly the problem of toxic and side effects on the liver and other organs still exists.
Disclosure of Invention
The embodiment of the invention aims to provide a traditional Chinese medicine composition to solve the problems that most of the existing medicines for treating bone injuries and bone diseases in the background art are oral medicines and have toxic and side effects on livers and other organs.
In order to achieve the purpose, the invention provides the following technical scheme:
a traditional Chinese medicine composition comprises the following raw materials in parts by weight: 90-130 parts of radix rehmanniae, 90-160 parts of rhubarb, 320 parts of notopterygium root 180-.
As a further scheme of the invention: the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 100 portions of dried rehmannia root, 100 portions of rhubarb, 150 portions of notopterygium root, 200 portions of angelica, 180 portions of dahurian angelica root, 200 portions of dragon's blood, 180 portions of safflower, 200 portions of weeping forsythia, 300 portions of liquorice, and 100 portions of borneol.
As a still further scheme of the invention: the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 100 portions of dried rehmannia root, 100 portions of rhubarb, 150 portions of notopterygium root, 200 portions of angelica, 180 portions of dahurian angelica root, 200 portions of dragon's blood, 180 portions of safflower, 200 portions of weeping forsythia, 300 portions of liquorice, and 150 portions of borneol.
As a still further scheme of the invention: the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 110 parts of dried rehmannia root, 125 parts of rhubarb, 250 parts of notopterygium root, 165 parts of angelica dahurica, 225 parts of dragon's blood, 165 parts of safflower, 200 parts of weeping forsythia capsule, 275 parts of liquorice and 125 parts of borneol.
It should be noted that the dried rehmannia root, rhubarb, notopterygium root, dahurian angelica root, dragon's blood, safflower, forsythia, licorice and borneol are all the names of traditional Chinese medicines. For example, the rehmannia glutinosa Libosch is named as a traditional Chinese medicine, is fresh or dried root tuber of rehmannia glutinosa Libosch of Scrophulariaceae family, is harvested in autumn, is removed of rhizoma Phragmitis, fibrous root and silt, is used fresh or after processing, and is divided into fresh rehmannia glutinosa Libosch, dried rehmannia glutinosa Libosch and prepared rehmannia root, and the rehmannia glutinosa Libosch has the effects of clearing heat in blood, nourishing yin and removing yang. It is indicated for fever and fatigue of women after honeyed pill, and for fever, polydipsia and coma in children after decocted with honey.
Another object of the embodiments of the present invention is to provide a method for preparing a Chinese medicinal composition, which comprises the following steps:
1) weighing the dried rehmannia root, the rhubarb, the notopterygium root, the angelica dahurica, the dragon's blood, the safflower, the forsythia, the liquorice and the borneol according to the weight part ratio, mixing the materials together, putting the mixture into sesame oil for soaking, pouring the mixture into a container for decocting, and removing impurities to obtain medicinal oil;
2) adding yellow lead into the medicinal oil obtained in the step 1) to prepare paste to obtain the traditional Chinese medicine composition, and specifically adding yellow lead into the medicinal oil, continuously stirring in the same direction, and stirring to obtain viscous paste.
As a still further scheme of the invention: in the preparation method of the traditional Chinese medicine composition, the soaking is to soak the raw materials of the root of rehmannia, the rhubarb, the notopterygium root, the angelica dahurica, the dragon's blood, the safflower, the forsythia, the liquorice, the borneol and the like in the sesame oil for 5 to 9 days.
Preferably, in the preparation method of the traditional Chinese medicine composition, the soaking is to soak the raw materials of the root of rehmannia, the rhubarb, the notopterygium root, the angelica dahurica, the dragon's blood, the safflower, the forsythia, the liquorice, the borneol and the like in the sesame oil for 7 days.
As a still further scheme of the invention: in the preparation method of the traditional Chinese medicine composition, the dosage of the sesame oil is 0.1-100 times of the total weight of the radix rehmanniae, the rhubarb, the notopterygium root, the angelica dahurica, the dragon's blood, the safflower, the forsythia, the liquorice and the borneol.
As a still further scheme of the invention: in the preparation method of the traditional Chinese medicine composition, the container can be an existing product such as a marmite, a copper pot and an iron pot, and preferably, the container is a copper pot.
As a still further scheme of the invention: in the preparation method of the traditional Chinese medicine composition, the impurity removal is carried out by pouring sesame oil soaked with radix rehmanniae, rhubarb, notopterygium root, angelica dahurica, dragon's blood, safflower, forsythia, liquorice and borneol into a copper pot, decocting with fire until the surface of the raw material (medicine) is dark brown and the interior of the raw material (medicine) is dark yellow, and then fishing out the raw material (medicine) with the dark brown surface and the interior of the raw material (medicine) which is dark brown.
As a still further scheme of the invention: in the preparation method of the traditional Chinese medicine composition, the adding amount of the yellow lead is 0.001-1 time of the weight of the medicinal oil.
As a still further scheme of the invention: the preparation method of the traditional Chinese medicine composition further comprises the step of soaking the paste in water, and specifically, the paste is soaked in cold water, water is changed once a day, and the paste is formed after six to eight days to play a role in removing fire toxin, so that the traditional Chinese medicine composition is obtained.
Another object of the embodiments of the present invention is to provide a Chinese medicinal composition prepared by the above method.
As a still further scheme of the invention: the traditional Chinese medicine composition is applied to preparation of medicines for treating bone injuries and/or bone diseases.
Another objective of the embodiments of the present invention is to provide an external use medicine, which partially or completely contains the above-mentioned Chinese medicinal composition.
As a still further scheme of the invention: the dosage form of the external medicine is any one of lotion, paste or spray.
Preferably, the external preparation may be a paste, i.e., a plaster.
The embodiment of the invention also aims to provide application of the externally applied medicine in preparing medicines for treating bone injuries and/or bone diseases.
As a still further scheme of the invention: in the application of the external medicine in preparing the medicine for treating bone fracture and/or bone disease, the bone fracture and/or bone disease can be various fractures and dislocation, and can also be neck, shoulder, waist and leg pain, tenosynovitis, cervical, thoracic and lumbar hyperplasia, cervical, thoracic and lumbar herniation and the like.
Compared with the prior art, the invention has the beneficial effects that:
the traditional Chinese medicine composition prepared by the invention is a pure traditional Chinese medicine for external use, has no toxic or side effect, has excellent treatment effect on bone injury and bone disease through reasonable compatibility of traditional Chinese medicines such as radix rehmanniae, rheum officinale, notopterygium root, radix angelicae, dragon's blood, safflower, fructus forsythiae, liquorice, borneol and the like, is suitable for various bone injury and bone disease such as various fractures and dislocation, neck, shoulder, waist and leg pain, tenosynovitis, cervical, thoracic and lumbar hyperplasia and protrusion and the like, has a simple preparation method, is low in price, wide in adaptation syndrome, convenient to use, free of hospitalization, safe to use and free of toxic or side effect, solves the problem that most of the existing medicines for treating bone injury and bone disease are oral medicines and have toxic or side effect on liver and other organs, and has a wide market prospect.
Detailed Description
The present invention will be described in further detail with reference to specific examples. The following examples will assist those skilled in the art in further understanding the invention, but are not intended to limit the invention in any way. It should be noted that variations and modifications can be made by persons skilled in the art without departing from the spirit of the invention. All falling within the scope of the present invention.
Example 1
A traditional Chinese medicine composition comprises the following raw materials: 90 g of dried rehmannia root, 90 g of rhubarb, 180 g of notopterygium root, 140 g of angelica dahurica, 180 g of dragon's blood, 140 g of safflower, 180 g of weeping forsythia, 240 g of liquorice and 90 g of borneol.
In this embodiment, the preparation method of the Chinese medicinal composition is as follows:
1) weighing the dried rehmannia root, the rhubarb, the notopterygium root, the angelica dahurica, the dragon's blood, the safflower, the forsythia, the liquorice and the borneol, mixing the materials together, placing the mixture into sesame oil for soaking for 5 days, pouring the mixture into a copper pot, decocting the mixture with fire until the surfaces of the medicinal raw materials are dark brown and the interior of the medicinal raw materials is dark yellow, fishing out the medicinal raw materials with the surfaces of dark brown and the interior of the medicinal raw materials, and removing impurities to obtain medicinal oil;
2) adding Plumbum preparatium into the medicinal oil obtained in step 1) to obtain paste, and stirring to obtain viscous paste.
In this embodiment, the amount of the sesame oil is 0.1 times of the total weight of the radix rehmanniae, the rheum officinale, the notopterygium root, the radix angelicae, the dragon's blood, the safflower, the fructus forsythiae, the liquorice and the borneol, and the amount of the yellow lead is 0.001 times of the weight of the medicinal oil.
Example 2
A traditional Chinese medicine composition comprises the following raw materials: 130 g of dried rehmannia root, 160 g of rhubarb, 320 g of notopterygium root, 190 g of angelica dahurica, 260 g of dragon's blood, 190 g of safflower, 220 g of forsythia, 320 g of liquorice and 160 g of borneol.
In this embodiment, the preparation method of the Chinese medicinal composition is as follows:
1) weighing the dried rehmannia root, the rhubarb, the notopterygium root, the angelica dahurica, the dragon's blood, the safflower, the forsythia, the liquorice and the borneol, mixing the materials together, placing the mixture into sesame oil for soaking for 9 days, pouring the mixture into a copper pot, decocting the mixture with fire until the surfaces of the medicinal raw materials are dark brown and the interior of the medicinal raw materials is dark yellow, fishing out the medicinal raw materials with the surfaces of dark brown and the interior of the medicinal raw materials, and removing impurities to obtain medicinal oil;
2) adding Plumbum preparatium into the medicinal oil obtained in step 1) to obtain paste, and stirring to obtain viscous paste.
In this embodiment, the amount of the sesame oil is 100 times of the total weight of the radix rehmanniae, the rheum officinale, the notopterygium root, the radix angelicae, the dragon's blood, the safflower, the fructus forsythiae, the liquorice and the borneol, and the amount of the yellow lead added is 1 time of the weight of the medicinal oil.
Example 3
A traditional Chinese medicine composition comprises the following raw materials: 114 g of dried rehmannia root, 120 g of rhubarb, 250 g of notopterygium root, 177 g of angelica dahurica, 220 g of dragon's blood, 170 g of safflower, 200 g of weeping forsythia, 280 g of liquorice and 120 g of borneol.
In this embodiment, the preparation method of the Chinese medicinal composition is as follows:
1) weighing the dried rehmannia root, the rhubarb, the notopterygium root, the angelica dahurica, the dragon's blood, the safflower, the forsythia, the liquorice and the borneol, mixing the materials together, placing the mixture into sesame oil for soaking for 8 days, pouring the mixture into a copper pot, decocting the mixture with fire until the surfaces of the medicinal raw materials are dark brown and the interior of the medicinal raw materials is dark yellow, fishing out the medicinal raw materials with the surfaces of dark brown and the interior of the medicinal raw materials, and removing impurities to obtain medicinal oil;
2) adding Plumbum preparatium into the medicinal oil obtained in step 1) to obtain paste, and stirring to obtain viscous paste.
In this embodiment, the amount of the sesame oil is 0.5 times of the total weight of the radix rehmanniae, the rheum officinale, the notopterygium root, the radix angelicae, the dragon's blood, the safflower, the fructus forsythiae, the liquorice and the borneol, and the amount of the yellow lead is 0.01 times of the weight of the medicinal oil.
Example 4
The same as example 1 except that the copper pan was replaced with a casserole, as compared with example 1.
Example 5
The same as example 1 except that the copper pan was replaced with an iron pan as compared with example 1.
Example 6
Same as example 1 except that the soaking time was changed to 7 days, compared with example 1.
Example 7
Compared with the embodiment 3, the sesame oil is the same as the embodiment 3 except that the dosage of the sesame oil is 1 time of the total weight of the rehmannia root, the rhubarb, the notopterygium root, the angelica dahurica, the dragon's blood, the safflower, the weeping forsythia, the liquorice and the borneol.
Example 8
Compared with the embodiment 3, the sesame oil is the same as the embodiment 3 except that the dosage of the sesame oil is 4 times of the total weight of the rehmannia root, the rhubarb, the notopterygium root, the angelica dahurica, the dragon's blood, the safflower, the weeping forsythia, the liquorice and the borneol.
Example 9
Compared with the embodiment 3, the sesame oil is the same as the embodiment 3 except that the dosage of the sesame oil is 10 times of the total weight of the rehmannia root, the rhubarb, the notopterygium root, the angelica dahurica, the dragon's blood, the safflower, the weeping forsythia, the liquorice and the borneol.
Example 10
Compared with the embodiment 3, the sesame oil is the same as the embodiment 3 except that the dosage of the sesame oil is 50 times of the total weight of the rehmannia root, the rhubarb, the notopterygium root, the angelica dahurica, the dragon's blood, the safflower, the weeping forsythia, the liquorice and the borneol.
Example 11
Compared with the example 8, the method is the same as the example 8 except that the adding amount of the yellow lead is 0.1 time of the weight of the medicinal oil.
Example 12
Compared with the example 8, the method is the same as the example 8 except that the adding amount of the yellow lead is 0.2 times of the weight of the medicinal oil.
Example 13
Compared with the example 8, the method is the same as the example 8 except that the adding amount of the yellow lead is 0.4 times of the weight of the medicinal oil.
Example 14
Compared with the example 8, the method is the same as the example 8 except that the adding amount of the yellow lead is 0.6 times of the weight of the medicinal oil.
Example 15
Compared with the example 8, the method is the same as the example 8 except that the adding amount of the yellow lead is 0.8 times of the weight of the medicinal oil.
Example 16
A traditional Chinese medicine composition comprises the following raw materials: 100 g of dried rehmannia root, 100 g of rhubarb, 200 g of notopterygium root, 150 g of angelica dahurica, 200 g of dragon's blood, 150 g of safflower, 200 g of weeping forsythia, 250 g of liquorice and 100 g of borneol.
In this embodiment, the preparation method of the Chinese medicinal composition is as follows:
1) weighing the dried rehmannia root, the rhubarb, the notopterygium root, the angelica dahurica, the dragon's blood, the safflower, the forsythia, the liquorice and the borneol, mixing the materials together, placing the mixture into sesame oil for soaking for 7 days, pouring the mixture into a copper pot, decocting the mixture with fire until the surfaces of the medicinal raw materials are dark brown and the interior of the medicinal raw materials is dark yellow, fishing out the medicinal raw materials with the surfaces of dark brown and the interior of the medicinal raw materials, and removing impurities to obtain medicinal oil;
2) adding yellow lead into the medicinal oil obtained in the step 1) to prepare paste, and specifically adding yellow lead into the medicinal oil, continuously stirring in the same direction, stirring to obtain viscous paste, then soaking the paste in cold water, changing water once a day, and forming the paste after seven days to obtain the traditional Chinese medicine composition.
In this embodiment, the amount of the sesame oil is 2 times of the total weight of the radix rehmanniae, the rheum officinale, the notopterygium root, the radix angelicae, the dragon's blood, the safflower, the fructus forsythiae, the liquorice and the borneol, and the amount of the yellow lead added is 0.15 times of the weight of the medicinal oil.
Example 17
A traditional Chinese medicine composition comprises the following raw materials: 120 g of dried rehmannia root, 150 g of rhubarb, 300 g of notopterygium root, 180 g of angelica dahurica, 250 g of dragon's blood, 180 g of safflower, 210 g of forsythia, 300 g of liquorice and 150 g of borneol.
In this embodiment, the preparation method of the Chinese medicinal composition is as follows:
1) weighing the dried rehmannia root, the rhubarb, the notopterygium root, the angelica dahurica, the dragon's blood, the safflower, the forsythia, the liquorice and the borneol, mixing the materials together, placing the mixture into sesame oil for soaking for 7 days, pouring the mixture into a copper pot, decocting the mixture with fire until the surfaces of the medicinal raw materials are dark brown and the interior of the medicinal raw materials is dark yellow, fishing out the medicinal raw materials with the surfaces of dark brown and the interior of the medicinal raw materials, and removing impurities to obtain medicinal oil;
2) adding yellow lead into the medicinal oil obtained in the step 1) to prepare paste, and specifically adding yellow lead into the medicinal oil, continuously stirring in the same direction, stirring to obtain viscous paste, then soaking the paste in cold water, changing water once a day, and forming the paste after seven days to obtain the traditional Chinese medicine composition.
In this embodiment, the amount of the sesame oil is 2 times of the total weight of the radix rehmanniae, the rheum officinale, the notopterygium root, the radix angelicae, the dragon's blood, the safflower, the fructus forsythiae, the liquorice and the borneol, and the amount of the yellow lead added is 0.15 times of the weight of the medicinal oil.
Example 18
A traditional Chinese medicine composition comprises the following raw materials: 110 g of dried rehmannia root, 125 g of rhubarb, 250 g of notopterygium root, 165 g of angelica dahurica, 210 g of dragon's blood, 170 g of safflower, 200 g of weeping forsythia, 270 g of liquorice and 125 g of borneol.
In this embodiment, the preparation method of the Chinese medicinal composition is as follows:
1) weighing the dried rehmannia root, the rhubarb, the notopterygium root, the angelica dahurica, the dragon's blood, the safflower, the forsythia, the liquorice and the borneol, mixing the materials together, placing the mixture into sesame oil for soaking for 8 days, pouring the mixture into a copper pot, decocting the mixture with fire until the surfaces of the medicinal raw materials are dark brown and the interior of the medicinal raw materials is dark yellow, fishing out the medicinal raw materials with the surfaces of dark brown and the interior of the medicinal raw materials, and removing impurities to obtain medicinal oil;
2) adding yellow lead into the medicinal oil obtained in the step 1) to prepare paste, and specifically adding yellow lead into the medicinal oil, continuously stirring in the same direction, stirring to obtain viscous paste, then soaking the paste in cold water, changing water once a day, and forming the paste after seven days to obtain the traditional Chinese medicine composition.
In this embodiment, the amount of the sesame oil is 2 times of the total weight of the radix rehmanniae, the rheum officinale, the notopterygium root, the radix angelicae, the dragon's blood, the safflower, the fructus forsythiae, the liquorice and the borneol, and the amount of the yellow lead added is 0.15 times of the weight of the medicinal oil.
Example 19
The externally applied medicine is in the form of ointment (namely plaster), and comprises the following raw materials: 110 g of dried rehmannia root, 125 g of rhubarb, 250 g of notopterygium root, 165 g of angelica dahurica, 225 g of dragon's blood, 165 g of safflower, 200 g of weeping forsythia capsule, 275 g of liquorice and 125 g of borneol.
In this example, the preparation method of the external preparation is as follows:
1) weighing the dried rehmannia root, the rhubarb, the notopterygium root, the angelica dahurica, the dragon's blood, the safflower, the forsythia, the liquorice and the borneol, mixing the materials together, placing the mixture into sesame oil for soaking for 7 days, pouring the mixture into a copper pot, decocting the mixture with fire until the surfaces of the medicinal raw materials are dark brown and the interior of the medicinal raw materials is dark yellow, fishing out the medicinal raw materials with the surfaces of dark brown and the interior of the medicinal raw materials, and removing impurities to obtain medicinal oil;
2) adding yellow lead into the medicinal oil obtained in the step 1) to prepare paste, and specifically adding yellow lead into the medicinal oil, continuously stirring in the same direction, stirring to form viscous paste, then soaking the paste in cold water, changing water once a day, and forming the paste after seven days to obtain the external medicament.
In this embodiment, the amount of the sesame oil is 2 times of the total weight of the radix rehmanniae, the rheum officinale, the notopterygium root, the radix angelicae, the dragon's blood, the safflower, the fructus forsythiae, the liquorice and the borneol, and the amount of the yellow lead added is 0.15 times of the weight of the medicinal oil.
Example 20
The external use medicine (i.e. plaster) prepared in example 19 was subjected to efficacy verification, specifically: zhou Sheng xing, family chatting in the high and new town, car accident causes femoral neck fracture; the plaster is externally applied after the patient is hospitalized in a hospital with the city being in charge and the operation treatment is required, the fracture line becomes fuzzy after 20 days, the patient can walk on the ground after 40 days, and the recovery is realized. Moreover, the plaster on the market has great stimulation to the skin, and easily causes skin allergy and skin ulceration. The invention adopts pure traditional Chinese medicine decoction, adheres to the ancient method for decoction, removes fire toxin, has no stimulation to skin, and cannot cause skin allergy. Meanwhile, the traditional Chinese medicine composition is low in price, wide in adaptation syndrome, convenient to use, free of hospitalization, suitable for various fractures and dislocation, suitable for various bone fracture and bone diseases such as neck, shoulder, waist and leg pain, tenosynovitis, cervical, thoracic and lumbar hyperplasia, protrusion and the like, safe to use, free of toxic and side effects, safe and reliable.
The invention is characterized in that the invention is pure traditional Chinese medicine, has remarkable curative effect and rapid effect, is applied to the local position of the wound and the patient, and the medicine in the local tissue is remarkably higher than the blood concentration, so the invention has full and rapid effect, the local curative effect is obviously better than the oral administration, and the invention is very suitable for the patients who are inconvenient to take the medicine or do not want to take the medicine, and has no any toxic or side effect because the invention does not pass through any organ of the patient, and has no any stimulation to the skin, thereby the invention can be used safely. The traditional Chinese medicine composition is directly applied to the external acupuncture points or the affected parts of patients, the medicine property penetrates through skin and hair striae from outside to inside and permeates to subcutaneous tissues, and the functions of dredging the meridian, removing stagnation and removing blood stasis, inducing resuscitation and penetrating bones, relaxing muscles and tendons, promoting blood circulation, reducing swelling and removing blood stasis, expelling wind and removing cold of the medicine are exerted by means of the channels, so that the purpose of curing diseases is achieved, the toxic and side effects of the oral medicine are avoided, the medicine resistance is not easy to generate, the curative effect is obvious, the effect is quick, the use is safe, and the toxic and side effects.
While the preferred embodiments of the present invention have been described in detail, the present invention is not limited to the above embodiments, and various changes can be made without departing from the spirit of the present invention within the knowledge of those skilled in the art. And are neither required nor exhaustive of all embodiments. And obvious variations or modifications of the invention may be made without departing from the scope of the invention.

Claims (10)

1. The traditional Chinese medicine composition is characterized by comprising the following raw materials in parts by weight: 90-130 parts of radix rehmanniae, 90-160 parts of rhubarb, 320 parts of notopterygium root 180-.
2. The traditional Chinese medicine composition according to claim 1, wherein the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 100 portions of dried rehmannia root, 100 portions of rhubarb, 150 portions of notopterygium root, 200 portions of angelica, 180 portions of dahurian angelica root, 200 portions of dragon's blood, 180 portions of safflower, 200 portions of weeping forsythia, 300 portions of liquorice, and 100 portions of borneol.
3. A method for preparing a Chinese medicinal composition as claimed in any one of claims 1-2, comprising the steps of:
1) weighing radix rehmanniae, radix et rhizoma Rhei, Notopterygii rhizoma, radix Angelicae Dahuricae, sanguis Draxonis, Carthami flos, fructus forsythiae, Glycyrrhrizae radix and Borneolum Syntheticum at a certain proportion, soaking in oleum Sesami, pouring into a container, decocting, and removing impurities to obtain medicinal oil;
2) and adding yellow lead into the medicinal oil to prepare paste to obtain the traditional Chinese medicine composition.
4. The method for preparing a Chinese medicinal composition according to claim 3, wherein the soaking time is 5 to 9 days.
5. The method of claim 3, wherein the amount of the sesame oil is 0.1-100 times of the total weight of the rehmannia root, the rhubarb, the notopterygium root, the angelica root, the dragon's blood, the safflower, the forsythia, the liquorice and the borneol.
6. The method for preparing a Chinese medicinal composition according to claim 3, further comprising the step of soaking the ointment in water.
7. A Chinese medicinal composition prepared by the preparation method of the Chinese medicinal composition of any one of claims 3-6.
8. An external preparation characterized by comprising the Chinese medicinal composition as claimed in claim 1, 2 or 7 partially or entirely.
9. The external preparation for external use as claimed in claim 8, wherein the formulation of the external preparation is any one of a paste, a lotion or a spray.
10. Use of an external medicament as claimed in any one of claims 8 to 9 in the manufacture of a medicament for the treatment of bone injury and/or bone disease.
CN202010607644.2A 2020-06-30 2020-06-30 Traditional Chinese medicine composition, preparation method thereof, external medicine and application thereof Pending CN111529609A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1357358A (en) * 2001-03-28 2002-07-10 郭伯学 Blood circulation activating and pain stopping ointment for treating bone injury and its prepn process
KR100373497B1 (en) * 2001-10-27 2003-02-25 Jung Keun Kim Extract of rehmanniae radix and pharmaceutical composition containing the same for facilitating bone formation of children and for prevention and treatment of bone diseases such as osteoporosis
CN109731026A (en) * 2018-12-20 2019-05-10 内蒙古民族大学附属医院 A kind of externally used Mongolian medicine of set a broken bone and preparation method thereof
CN110064010A (en) * 2019-05-18 2019-07-30 王震 A kind of plaster and preparation method thereof with anti-inflammatory analgetic wind-dispelling exsiccation

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1357358A (en) * 2001-03-28 2002-07-10 郭伯学 Blood circulation activating and pain stopping ointment for treating bone injury and its prepn process
KR100373497B1 (en) * 2001-10-27 2003-02-25 Jung Keun Kim Extract of rehmanniae radix and pharmaceutical composition containing the same for facilitating bone formation of children and for prevention and treatment of bone diseases such as osteoporosis
CN109731026A (en) * 2018-12-20 2019-05-10 内蒙古民族大学附属医院 A kind of externally used Mongolian medicine of set a broken bone and preparation method thereof
CN110064010A (en) * 2019-05-18 2019-07-30 王震 A kind of plaster and preparation method thereof with anti-inflammatory analgetic wind-dispelling exsiccation

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Application publication date: 20200814