CN111529051B - 一种预测电脉冲消融区域的系统 - Google Patents
一种预测电脉冲消融区域的系统 Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
- A61B2018/00577—Ablation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00827—Current
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00892—Voltage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00898—Alarms or notifications created in response to an abnormal condition
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- Health & Medical Sciences (AREA)
- Surgery (AREA)
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- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Otolaryngology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plasma & Fusion (AREA)
- Physics & Mathematics (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
Abstract
Description
D<sub>1</sub> | D<sub>2</sub> | … | D<sub>n</sub> | |
R<sub>sig1</sub> | S<sub>11</sub> | S<sub>12</sub> | … | S<sub>1n</sub> |
R<sub>sig2</sub> | S<sub>21</sub> | S<sub>22</sub> | … | S<sub>2n</sub> |
… | … | … | … | … |
R<sub>sigm</sub> | S<sub>m1</sub> | S<sub>m2</sub> | … | S<sub>mn</sub> |
E<sub>1</sub> | E<sub>2</sub> | … | E<sub>n</sub> | |
D<sub>1</sub> | M<sub>11</sub>,N<sub>11</sub> | M<sub>12</sub>,N<sub>12</sub> | … | M<sub>1n</sub>,N<sub>1n</sub> |
D<sub>2</sub> | M<sub>21</sub>,N<sub>21</sub> | M<sub>22</sub>,N<sub>22</sub> | … | M<sub>2n</sub>,N<sub>2n</sub> |
… | … | … | … | … |
D<sub>m</sub> | M<sub>m1</sub>,N<sub>m1</sub> | M<sub>m2</sub>,N<sub>m2</sub> | … | M<sub>mn</sub>,N<sub>mn</sub> |
R<sub>1</sub> | R<sub>2</sub> | … | R<sub>n</sub> |
M<sub>1</sub>,N<sub>1</sub> | M<sub>2</sub>,N<sub>2</sub> | … | M<sub>n</sub>,N<sub>n</sub> |
Claims (19)
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CN202010301885.4A CN111529051B (zh) | 2020-04-16 | 2020-04-16 | 一种预测电脉冲消融区域的系统 |
PCT/CN2020/108971 WO2021208306A1 (zh) | 2020-04-16 | 2020-08-13 | 一种预测电脉冲消融区域的系统 |
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WO (1) | WO2021208306A1 (zh) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111529052B (zh) * | 2020-04-16 | 2021-05-07 | 上海睿刀医疗科技有限公司 | 一种预测电脉冲消融区域的系统 |
CN112489741B (zh) * | 2020-11-13 | 2021-11-05 | 上海睿刀医疗科技有限公司 | 一种脉冲电场消融参数优化系统 |
CN112315578B (zh) * | 2020-11-20 | 2021-06-15 | 上海睿刀医疗科技有限公司 | 确定电极针布针组合的装置、方法及电极针布针优化系统 |
CN112315579B (zh) * | 2020-11-25 | 2021-07-02 | 上海睿刀医疗科技有限公司 | 一种基于病灶区域的电极针布针装置及方法 |
CN112603536A (zh) * | 2020-12-29 | 2021-04-06 | 北京华科恒生医疗科技有限公司 | 三维模型中生成电极热凝参数的方法和系统 |
CN112998844B (zh) * | 2021-02-05 | 2021-12-21 | 上海睿刀医疗科技有限公司 | 一种球囊电极导管 |
CN112998845B (zh) * | 2021-02-08 | 2021-12-21 | 上海睿刀医疗科技有限公司 | 一种多电极消融针以及多电极消融针电极间距的确定方法 |
CN114869455B (zh) * | 2021-05-27 | 2025-05-30 | 上海商阳医疗科技有限公司 | 脉冲消融参数的获取方法、系统、电子设备和存储介质 |
CN113380394B (zh) * | 2021-06-18 | 2022-04-12 | 上海睿刀医疗科技有限公司 | 确定电极针消融边界的方法、装置、电子设备及存储介质 |
CN113705807B (zh) * | 2021-08-26 | 2022-06-10 | 上海睿刀医疗科技有限公司 | 神经网络的训练装置及方法,消融布针规划装置及方法 |
CN116983085A (zh) * | 2023-09-25 | 2023-11-03 | 上海微创电生理医疗科技股份有限公司 | 一种消融灶尺寸预测系统及消融设备 |
CN117695005B (zh) * | 2024-02-05 | 2024-05-07 | 浙江伽奈维医疗科技有限公司 | 一种具有布针引导功能的陡脉冲治疗系统 |
CN118356247B (zh) * | 2024-06-19 | 2024-09-13 | 杭州睿笛生物科技有限公司 | 一种基于单针多极型电极针的脉冲电场肿瘤消融治疗系统和装置 |
CN118370600B (zh) * | 2024-06-25 | 2024-09-24 | 杭州睿笛生物科技有限公司 | 一种基于单针多极型电极针的术前方案生成系统和装置 |
CN118542728B (zh) * | 2024-07-29 | 2024-10-15 | 天津市鹰泰利安康医疗科技有限责任公司 | 一种脉管内的不可逆电穿孔消融的系统 |
CN118873240A (zh) * | 2024-09-30 | 2024-11-01 | 杭州睿笛生物科技有限公司 | 一种基于局部阻抗检测进行实时脉冲电场消融评估的装置和方法 |
CN119026430B (zh) * | 2024-10-25 | 2025-03-04 | 浙江理工大学 | 基于uv涂覆技术的麻醉穿刺针电解加工杂散腐蚀抑制方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103717167A (zh) * | 2011-07-28 | 2014-04-09 | 皇家飞利浦有限公司 | 消融规划系统 |
CN108830017A (zh) * | 2018-07-05 | 2018-11-16 | 上海交通大学 | 基于个体阻抗的射频加热温度场预测方法及其系统 |
CN110432977A (zh) * | 2019-08-07 | 2019-11-12 | 杭州睿笛生物科技有限公司 | 一种电脉冲消融设备以及适用其仿真方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9283051B2 (en) * | 2008-04-29 | 2016-03-15 | Virginia Tech Intellectual Properties, Inc. | System and method for estimating a treatment volume for administering electrical-energy based therapies |
US11272979B2 (en) * | 2008-04-29 | 2022-03-15 | Virginia Tech Intellectual Properties, Inc. | System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies |
US10117707B2 (en) * | 2008-04-29 | 2018-11-06 | Virginia Tech Intellectual Properties, Inc. | System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies |
US9198733B2 (en) * | 2008-04-29 | 2015-12-01 | Virginia Tech Intellectual Properties, Inc. | Treatment planning for electroporation-based therapies |
CN102421386A (zh) * | 2009-03-31 | 2012-04-18 | 安吉戴尼克公司 | 用于估计医疗装置的治疗区和互动式地计划患者治疗的系统和方法 |
EP2627274B1 (en) * | 2010-10-13 | 2022-12-14 | AngioDynamics, Inc. | System for electrically ablating tissue of a patient |
CN105534593B (zh) * | 2014-10-29 | 2019-04-23 | 深圳迈瑞生物医疗电子股份有限公司 | 介入消融模拟系统及方法 |
CN109157280A (zh) * | 2018-08-10 | 2019-01-08 | 重庆大学 | 不可逆电穿孔组织消融效果动态实时评估设备 |
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- 2020-04-16 CN CN202010301885.4A patent/CN111529051B/zh active Active
- 2020-08-13 WO PCT/CN2020/108971 patent/WO2021208306A1/zh active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103717167A (zh) * | 2011-07-28 | 2014-04-09 | 皇家飞利浦有限公司 | 消融规划系统 |
CN108830017A (zh) * | 2018-07-05 | 2018-11-16 | 上海交通大学 | 基于个体阻抗的射频加热温度场预测方法及其系统 |
CN110432977A (zh) * | 2019-08-07 | 2019-11-12 | 杭州睿笛生物科技有限公司 | 一种电脉冲消融设备以及适用其仿真方法 |
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