CN111514248A - Traditional Chinese medicine formula for promoting rapid elimination of neonatal physiological jaundice and preparation method thereof - Google Patents

Traditional Chinese medicine formula for promoting rapid elimination of neonatal physiological jaundice and preparation method thereof Download PDF

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CN111514248A
CN111514248A CN202010421525.8A CN202010421525A CN111514248A CN 111514248 A CN111514248 A CN 111514248A CN 202010421525 A CN202010421525 A CN 202010421525A CN 111514248 A CN111514248 A CN 111514248A
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蔡建华
蔡镇宇
蔡涵宇
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Abstract

The invention relates to a traditional Chinese medicine formula for promoting quick elimination of neonatal physiological jaundice, which comprises the following raw materials in parts by weight: group A: 60-90 parts of oldenlandia diffusa, 60-90 parts of houttuynia cordata, 40-70 parts of selfheal, 80-120 parts of lysimachia christinae hance and 65-85 parts of hypericum japonicum; group B: 40-70 parts of longhairy antenoron herb, 65-85 parts of gardenia jasminoides, 50-80 parts of cogongrass rhizome, 45-65 parts of plantain herb and 45-65 parts of abrus cantoniensis hance; group C: 45-65 parts of wild chrysanthemum flower, 45-65 parts of lophatherum gracile, 40-65 parts of schisandra chinensis, 40-65 parts of isatis root and 20-60 parts of raw rhubarb; group D: 60-90 parts of sedum sarmentosum, 45-65 parts of Chinese knotweed herb and 65-85 parts of linearstripe rabdosia herb. The traditional Chinese medicine composition provided by the invention can radically cure neonatal jaundice and other problems by combining various medicines through monarch, minister, assistant and guide, and has the advantages of thorough treatment, obvious curative effect, quick response, short treatment course and high cure rate. Meanwhile, the traditional Chinese medicine formula has no adverse reaction and side effect, no dependence, safety and reliability.

Description

Traditional Chinese medicine formula for promoting rapid elimination of neonatal physiological jaundice and preparation method thereof
Technical Field
The invention relates to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine formula for promoting quick elimination of neonatal physiological jaundice and a preparation method thereof.
Background
The neonatal jaundice of a newborn in a short month (within 28 days of birth) is called neonatal jaundice (neonataljaundice) in medicine, and the neonatal jaundice refers to a disease characterized by yellow staining of skin, mucous membrane and sclera caused by the rise of the level of bilirubin in blood due to abnormal bilirubin metabolism in a neonatal period, and is the most common clinical problem in the newborn.
The current methods for treating physiological jaundice of newborn mainly comprise the following two methods:
(1) phototherapy, regular irradiation with blue light, has large side effects, and is easy to cause fever, diarrhea, rash, riboflavin deficiency, thrombocytopenia, bronze disease, etc.
(2) And (3) drug treatment: western medicines are mainly used for treatment, but the effect is slow, the side effect is large, and other diseases can be caused. However, the treatment efficiency of some common traditional Chinese medicines is not ideal, and the traditional Chinese medicine has slow and insignificant curative effect. In addition, some traditional Chinese medicines in the current market can treat jaundice, but most of the traditional Chinese medicines are used by adults, are specially developed for pathological jaundice, have certain side effects, and are not suitable for being taken for infants with physiological jaundice constitutions.
Disclosure of Invention
The present invention has an object to: provides a traditional Chinese medicine formula for promoting quick elimination of neonatal physiological jaundice.
In order to achieve the above purpose, the invention provides the following technical scheme:
a traditional Chinese medicine formula for promoting rapid elimination of neonatal physiological jaundice comprises the following raw materials in parts by weight:
group A: 60-90 parts of oldenlandia diffusa, 60-90 parts of houttuynia cordata, 40-70 parts of selfheal, 80-120 parts of lysimachia christinae hance and 65-85 parts of hypericum japonicum;
group B: 40-70 parts of longhairy antenoron herb, 65-85 parts of gardenia jasminoides, 50-80 parts of cogongrass rhizome, 45-65 parts of plantain herb and 45-65 parts of abrus cantoniensis hance;
group C: 45-65 parts of wild chrysanthemum flower, 45-65 parts of lophatherum gracile, 40-65 parts of schisandra chinensis, 40-65 parts of isatis root and 20-60 parts of raw rhubarb;
group D: 60-90 parts of sedum sarmentosum, 45-65 parts of Chinese knotweed herb and 65-85 parts of linearstripe rabdosia herb;
wherein, the weight ratio of the group A, the group B, the group C and the group D is 1: 1: 1: 1.
preferably, the traditional Chinese medicine formula for promoting quick elimination of neonatal physiological jaundice comprises the following raw materials in parts by weight:
group A: 70-80 parts of oldenlandia diffusa, 70-80 parts of houttuynia cordata, 50-60 parts of selfheal, 90-100 parts of lysimachia christinae hance and 70-80 parts of hypericum japonicum;
group B: 50-60 parts of longhairy antenoron herb, 70-80 parts of gardenia jasminoides, 60-70 parts of cogongrass rhizome, 50-60 parts of plantain herb and 50-60 parts of abrus cantoniensis hance;
group C: 50-60 parts of wild chrysanthemum flower, 50-60 parts of lophatherum gracile, 50-60 parts of Chinese magnoliavine fruit, 50-60 parts of isatis root and 30-50 parts of raw rhubarb;
group D: 70-80 parts of stringy stonecrop herb, 50-60 parts of Chinese knotweed herb and 70-80 parts of linearstripe rabdosia herb;
wherein, the weight ratio of the group A, the group B, the group C and the group D is 1: 1: 1: 1.
preferably, the traditional Chinese medicine formula for promoting quick elimination of neonatal physiological jaundice comprises the following raw materials in parts by weight:
group A: 75 parts of oldenlandia diffusa, 75 parts of houttuynia cordata, 55 parts of selfheal, 95 parts of lysimachia christinae hance and 75 parts of hypericum japonicum;
group B: 55 parts of longhairy antenoron herb, 75 parts of gardenia jasminoides, 66 parts of cogongrass rhizome, 58 parts of plantain herb and 55 parts of abrus herb;
group C: 55 parts of wild chrysanthemum, 57 parts of lophatherum gracile, 55 parts of Chinese magnoliavine fruit, 58 parts of isatis root and 40 parts of raw rhubarb;
group D: 75 parts of stringy stonecrop herb, 55 parts of Chinese knotweed herb and 75 parts of linearstripe rabdosia herb;
wherein, the weight ratio of the group A, the group B, the group C and the group D is 1: 1: 1: 1.
the second object of the present invention is to: provides a preparation method of a traditional Chinese medicine formula for promoting quick elimination of neonatal physiological jaundice.
In order to achieve the above purpose, the invention provides the following technical scheme:
a preparation method of a traditional Chinese medicine formula for promoting rapid elimination of neonatal physiological jaundice comprises the following specific steps:
(1) weighing the raw materials according to the weight parts, crushing and uniformly mixing for later use;
(2) soaking in water, decocting to obtain filtrate and residue, and concentrating the filtrate to obtain soft extract;
(3) soaking the filter residue obtained in the step (2) in ethanol, performing reflux extraction, filtering to obtain a filtrate, and concentrating the filtrate into a thick paste;
(4) and (3) combining the thick paste obtained in the step (2) and the step (3), drying and crushing to obtain the composition.
Preferably, the specific process of soaking in step (2) is as follows: adding water 8-10 times the weight of the raw materials, and soaking for 4-6 hours.
Preferably, the decocting time in the step (2) is 2-3 times, and each time is 0.8-1.5 hours.
Preferably, the relative density of the thick paste in the step (2) at 60 ℃ is 1.20-1.25 g/ml.
Preferably, the adding amount of the ethanol in the step (3) is 7-9 times of the weight of the filter residue obtained in the step (2), the soaking time is 4-6 hours, and the concentration of the ethanol is 60-65%.
Preferably, the reflux extraction in step (3) is performed 2 to 3 times each for 0.7 to 1 hour.
Preferably, the relative density of the thick paste in the step (3) is 1.20-1.25g/ml at 60 ℃.
The main effects of the raw materials used in the traditional Chinese medicine composition are as follows:
hedyotis diffusa: has the effects of clearing away heat and toxic materials, promoting blood circulation, removing blood stasis, promoting diuresis and eliminating jaundice; can be used for treating cough due to lung heat, lung abscess, swelling and pain of throat, intestinal abscess, furuncle, suppurative sore, venomous snake bite, stranguria with heat, edema, dysentery, enteritis, jaundice due to damp-heat pathogen, and cancer.
Houttuynia cordata: has the effects of clearing away heat and toxic materials, inducing diuresis and relieving swelling; can be used for treating pneumonia, lung abscess, dysentery, malaria, edema, gonorrhea, leucorrhea, carbuncle, hemorrhoid, proctoptosis, eczema, alopecia, scabies, and tinea.
Selfheal: has the effects of clearing heat and purging fire, improving eyesight, eliminating stagnation and reducing swelling; it is mainly used for treating conjunctival congestion, swelling and pain, headache, etc.
Herba Siphonostegiae: has the effects of clearing heat, promoting diuresis, cooling blood, stopping bleeding, removing blood stasis and relieving pain; can be used for treating icterohepatitis, cholecystitis, Vicia faba, urinary calculus, dysuresia, hematuria, hematochezia, and puerperal abdominal pain due to blood stasis; it is used externally to treat wound hemorrhage, burn and scald.
Herba Hyperici Japonici: has the effects of clearing away heat and toxic materials, promoting diuresis, eliminating jaundice, and relieving swelling and removing blood stasis; can be used for treating jaundice due to damp-heat pathogen, intestinal abscess, conjunctival congestion, swelling and pain, and sore and swelling due to toxic heat.
Herba Lysimachiae Christinae: has the effects of clearing away heat and toxic materials, promoting urination, removing urinary calculus, promoting blood circulation, and dispelling blood stasis; can be used for treating liver calculus, cholelithiasis, cholecystitis, icterohepatitis, urinary calculus, edema, traumatic injury, venomous snake bite, and muscarine and drug poisoning.
Yellow gardenia: has the effects of clearing heat, purging fire and cooling blood.
Cogongrass rhizome: has the effects of cooling blood, stopping bleeding, clearing heat and promoting urination; can be used for treating hematuria, polydipsia due to febrile disease, cough due to lung heat, emesis due to stomach heat, jaundice due to damp-heat pathogen, edema, oliguria, stranguria with heat, and pain.
Plantain herb: has effects of promoting urination, clearing heat away, improving eyesight, and eliminating phlegm. Can be used for treating urinary obstruction, stranguria with turbid urine, leukorrhagia, hematuria, jaundice, edema, dysentery, diarrhea, epistaxis, conjunctival congestion, sore throat, cough, skin ulcer, etc.
Abrus cantoniensis: has the effects of removing dampness and jaundice, clearing away heat and toxic materials, and soothing liver and relieving pain; it can be used for treating damp-heat type jaundice, hypochondriac discomfort, gastralgia, mammary abscess, and swelling and pain.
Wild chrysanthemum flower: has the effects of dispelling wind and heat, relieving swelling and removing toxic substances; it can be used for treating furuncle, carbuncle, swelling and sore throat, acute conjunctivitis, headache, and vertigo.
Herba lophatheri: has the effects of cooling, relieving fever, promoting urination and inducing spawning; can be used for treating chest heat, cough, hemoptysis, toxic heat wind, diabetes, erysipelas, phlegm, mania, vexation, aphonia, headache, palpitation, epidemic, and vexation.
Schisandra chinensis: has effects in astringing lung, relieving cough, tonifying, arresting seminal emission, relieving diarrhea, and arresting sweating; it can be used for treating cough and asthma due to lung deficiency, thirst, spontaneous perspiration, night sweat, fatigue, marasmus, nocturnal emission, chronic diarrhea, and chronic dysentery.
Radix isatidis: has the effects of clearing away heat and toxic materials, cooling blood and relieving sore throat; mainly treats exogenous fever, early warm disease, swollen and sore throat, warm poison and macula, mumps, erysipelas, carbuncle and sore toxin.
Raw rhubarb: has the effects of removing food retention, relieving constipation; it is used for treating gastrointestinal excessive heat accumulation, constipation.
Sedum sarmentosum bunge: has the effects of eliminating dampness, removing jaundice, clearing away heat and toxic materials; it is mainly used for treating damp-heat jaundice, dysuria, carbuncle, swelling and pyocutaneous disease.
Charcoal mother: has the effects of clearing heat, promoting diuresis, cooling blood, removing toxic substances, calming liver, improving eyesight, promoting blood circulation, and relaxing muscles and tendons; can be used for treating dysentery, diarrhea, laryngopharynx swelling and pain, diphtheria, cough due to lung heat, pertussis, hepatitis, leukorrhagia, cancer, otitis media, eczema, giddiness, tinnitus, corneal nebula, and traumatic injury.
Rabdosia lophanthide: has the effects of clearing heat, promoting diuresis, eliminating jaundice, eliminating dampness, cooling blood, and removing blood stasis; can be used for treating acute icterohepatitis, acute cholecystitis, dysentery, enteritis, and traumatic injury.
The invention has the beneficial effects that:
the invention follows the prescription and medication principle of the traditional Chinese medicine, carries out dialectical compatibility and prescription, selects the Yinzui grass, the fructus gardeniae, the hypericum japonicum and the linearstripe rabdosia herb as monarch drugs, and has the effects of benefiting gallbladder and removing jaundice; herba Hedyotidis Diffusae, fructus Schisandrae chinensis, herba abri, radix Isatidis, herba Sedi, and herba Lysimachiae Christinae are selected as ministerial drugs, and have effects of promoting bile flow, removing jaundice, and resisting virus; herba Houttuyniae, Prunellae Spica, flos Chrysanthemi Indici, and herb Polygoni chinensis are used as adjuvant drugs, and have effects of clearing away heat and toxic materials; the medicinal herbs of desmodium, cogongrass rhizome, plantain, lophatherum gracile and raw rhubarb are selected as guiding medicaments, so that the medicinal composition has the effects of expelling toxin and inducing diuresis. The traditional Chinese medicine composition provided by the invention can radically cure neonatal jaundice and other problems by combining various medicines through monarch, minister, assistant and guide, and has the advantages of thorough treatment, obvious curative effect, quick response, short treatment course and high cure rate. Meanwhile, the traditional Chinese medicine formula disclosed by the invention has no adverse reaction and side effect, no dependence, and is safe and reliable.
DETAILED DESCRIPTION OF EMBODIMENT (S) OF INVENTION
Example 1
A traditional Chinese medicine formula for promoting rapid elimination of neonatal physiological jaundice comprises the following raw materials in parts by weight:
group A: 60 parts of oldenlandia diffusa, 60 parts of houttuynia cordata, 40 parts of selfheal, 80 parts of lysimachia christinae hance and 65 parts of hypericum japonicum;
group B: 40 parts of longhairy antenoron herb, 65 parts of gardenia jasminoides, 50 parts of lalang grass rhizome, 45 parts of plantain herb and 45 parts of abrus herb;
group C: 45 parts of wild chrysanthemum, 45 parts of lophatherum gracile, 40 parts of Chinese magnoliavine fruit, 40 parts of isatis root and 20 parts of raw rhubarb;
group D: 60 parts of stringy stonecrop herb, 45 parts of Chinese knotweed herb and 65 parts of linearstripe rabdosia herb; wherein, the weight ratio of the group A, the group B, the group C and the group D is 1: 1: 1: 1.
the preparation method of the traditional Chinese medicine formula for promoting quick elimination of neonatal physiological jaundice comprises the following specific steps:
(1) weighing the raw materials according to the weight parts, crushing and uniformly mixing for later use;
(2) adding 8 times of water, soaking for 4 hr, decocting for 2 times (each time for 0.8 hr), filtering, mixing filtrates, and concentrating the filtrate to obtain soft extract with relative density of 1.20g/ml at 60 deg.C;
(3) adding 7 times of 60% ethanol by weight into the filter residue obtained in the step (2), soaking for 4 hours, extracting under reflux for 2 times, each time for 0.7 hour, filtering, mixing filtrates, and concentrating the filtrate to obtain soft extract with relative density of 1.20g/ml at 60 deg.C;
(4) and (3) combining the thick paste obtained in the step (2) and the step (3), drying and crushing to obtain the composition.
Example 2
A traditional Chinese medicine formula for promoting rapid elimination of neonatal physiological jaundice comprises the following raw materials in parts by weight:
group A: 90 parts of oldenlandia diffusa, 90 parts of houttuynia cordata, 70 parts of selfheal, 120 parts of lysimachia christinae hance and 85 parts of hypericum japonicum;
group B: 70 parts of longhairy antenoron herb, 85 parts of gardenia jasminoides, 80 parts of lalang grass rhizome, 65 parts of plantain herb and 65 parts of abrus cantoniensis hance;
group C: 65 parts of wild chrysanthemum flower, 65 parts of lophatherum gracile, 65 parts of Chinese magnoliavine fruit, 65 parts of isatis root and 60 parts of raw rhubarb;
group D: 90 parts of stringy stonecrop herb, 65 parts of Chinese knotweed herb and 85 parts of linearstripe rabdosia herb; wherein, the weight ratio of the group A, the group B, the group C and the group D is 1: 1: 1: 1.
the preparation method of the traditional Chinese medicine formula for promoting quick elimination of neonatal physiological jaundice comprises the following specific steps:
(1) weighing the raw materials according to the weight parts, crushing and uniformly mixing for later use;
(2) adding 10 times of water, soaking for 6 hr, decocting for 3 times (each time for 1.5 hr), filtering, mixing filtrates, and concentrating the filtrate to obtain soft extract with relative density of 1.25g/ml at 60 deg.C;
(3) adding 9 times of 65% ethanol by weight into the filter residue obtained in the step (2), soaking for 6 hours, extracting under reflux for 3 times, each time for 1 hour, filtering, combining the filtrates, and concentrating the filtrate to obtain a thick paste with a relative density of 1.25g/ml at 60 ℃;
(4) and (3) combining the thick paste obtained in the step (2) and the step (3), drying and crushing to obtain the composition.
Example 3
A traditional Chinese medicine formula for promoting rapid elimination of neonatal physiological jaundice comprises the following raw materials in parts by weight:
group A: 70 parts of oldenlandia diffusa, 70 parts of houttuynia cordata, 50 parts of selfheal, 90 parts of lysimachia christinae hance and 70 parts of hypericum japonicum;
group B: 50 parts of longhairy antenoron herb, 70 parts of gardenia jasminoides, 60 parts of lalang grass rhizome, 50 parts of plantain herb and 50 parts of abrus herb;
group C: 50 parts of wild chrysanthemum, 50 parts of lophatherum gracile, 50 parts of Chinese magnoliavine fruit, 50 parts of isatis root and 30 parts of raw rhubarb;
group D: 70 parts of stringy stonecrop herb, 50 parts of Chinese knotweed herb and 70 parts of linearstripe rabdosia herb; wherein, the weight ratio of the group A, the group B, the group C and the group D is 1: 1: 1: 1.
the preparation method of the traditional Chinese medicine formula for promoting quick elimination of neonatal physiological jaundice comprises the following specific steps:
(1) weighing the raw materials according to the weight parts, crushing and uniformly mixing for later use;
(2) adding 9 times of water, soaking for 5 hr, decocting for 2 times (each time for 1 hr), filtering, mixing filtrates, and concentrating the filtrate to obtain soft extract with relative density of 1.22g/ml at 60 deg.C;
(3) adding 8 times of 62% ethanol by weight into the filter residue obtained in the step (2), soaking for 5 hours, extracting under reflux for 2 times, each time for 0.8 hour, filtering, combining the filtrates, and concentrating the filtrate to obtain a thick paste with a relative density of 1.22g/ml at 60 ℃;
(4) and (3) combining the thick paste obtained in the step (2) and the step (3), drying and crushing to obtain the composition.
Example 4
A traditional Chinese medicine formula for promoting rapid elimination of neonatal physiological jaundice comprises the following raw materials in parts by weight:
group A: 80 parts of oldenlandia diffusa, 80 parts of houttuynia cordata, 60 parts of selfheal, 100 parts of lysimachia christinae hance and 80 parts of hypericum japonicum;
group B: 60 parts of longhairy antenoron herb, 80 parts of gardenia jasminoides, 70 parts of lalang grass rhizome, 60 parts of plantain herb and 60 parts of abrus herb;
group C: 60 parts of wild chrysanthemum, 60 parts of lophatherum gracile, 60 parts of Chinese magnoliavine fruit, 60 parts of isatis root and 50 parts of raw rhubarb;
group D: 80 parts of stringy stonecrop herb, 60 parts of Chinese knotweed herb and 80 parts of linearstripe rabdosia herb; wherein, the weight ratio of the group A, the group B, the group C and the group D is 1: 1: 1: 1.
the preparation method of the traditional Chinese medicine formula for promoting quick elimination of neonatal physiological jaundice comprises the following specific steps:
(1) weighing the raw materials according to the weight parts, crushing and uniformly mixing for later use;
(2) adding 8 times of water, soaking for 6 hr, decocting for 2 times (each time for 0.8 hr), filtering, mixing filtrates, and concentrating the filtrate to obtain soft extract with relative density of 1.25g/ml at 60 deg.C;
(3) adding 9 times of 65% ethanol by weight into the filter residue obtained in the step (2), soaking for 6 hours, extracting under reflux for 2 times, each time for 0.7 hour, filtering, combining the filtrates, and concentrating the filtrate to obtain a thick paste with a relative density of 1.25g/ml at 60 ℃;
(4) and (3) combining the thick paste obtained in the step (2) and the step (3), drying and crushing to obtain the composition.
Example 5
A traditional Chinese medicine formula for promoting rapid elimination of neonatal physiological jaundice comprises the following raw materials in parts by weight:
group A: 75 parts of oldenlandia diffusa, 75 parts of houttuynia cordata, 55 parts of selfheal, 95 parts of lysimachia christinae hance and 75 parts of hypericum japonicum;
group B: 55 parts of longhairy antenoron herb, 75 parts of gardenia jasminoides, 66 parts of cogongrass rhizome, 58 parts of plantain herb and 55 parts of abrus herb;
group C: 55 parts of wild chrysanthemum, 57 parts of lophatherum gracile, 55 parts of Chinese magnoliavine fruit, 58 parts of isatis root and 40 parts of raw rhubarb;
group D: 75 parts of stringy stonecrop herb, 55 parts of Chinese knotweed herb and 75 parts of linearstripe rabdosia herb; wherein, the weight ratio of the group A, the group B, the group C and the group D is 1: 1: 1: 1.
the preparation method of the traditional Chinese medicine formula for promoting quick elimination of neonatal physiological jaundice comprises the following specific steps:
(1) weighing the raw materials according to the weight parts, crushing and uniformly mixing for later use;
(2) adding 9 times of water, soaking for 5 hr, decocting for 2 times (each time for 0.8 hr), filtering, mixing filtrates, and concentrating the filtrate to obtain soft extract with relative density of 1.20g/ml at 60 deg.C;
(3) adding 8 times of 60% ethanol by weight into the filter residue obtained in the step (2), soaking for 5 hours, extracting under reflux for 2 times, each time for 0.8 hour, filtering, mixing filtrates, and concentrating the filtrate to obtain soft extract with relative density of 1.20g/ml at 60 deg.C;
(4) and (3) combining the thick paste obtained in the step (2) and the step (3), drying and crushing to obtain the composition.
And (3) clinical observation statistics:
1. observing an object:
534 cases of jaundice patients with the age of 5-28 days are selected for clinical observation, 348 cases of men and 186 cases of women are selected and divided into a treatment group and a control group, the number of men and women in the two groups of cases is the same, the severity of symptoms is basically consistent, no obvious difference exists, and the jaundice is comparable.
2. Selecting the medicines:
treatment groups: the medicine of the invention is taken in small package of 2 g/bag twice a day, one bag at a time, 2-4 days.
Control group: the oral liquid for removing jaundice is administered according to the instruction for 2-4 days.
3. And (3) judging the curative effect:
(1) and (3) curing: yellow staining of skin, mucous membrane and sclera, and disappearance of crying and anorexia symptoms.
(2) The method has the following advantages: the above symptoms are alleviated.
(3) And (4) invalidation: the symptoms are unchanged.
4. Results
The treatment results after 2 days of drug administration are shown in table 1 below:
TABLE 1 comparison of treatment results after 2 days of drug administration
Figure BDA0002497114210000121
The treatment results after taking the drugs for 3 days are shown in the following table 2:
TABLE 2 comparison of the results of 3-day treatment with the drugs
Figure BDA0002497114210000122
The treatment results after taking the drugs for 4 days are shown in the following table 3:
TABLE 3 comparison of the treatment results of 4 days after taking the medicine
Figure BDA0002497114210000123
As can be seen from table 1: the medicine is taken for 2 days, in a treatment group, 153 patients are cured, 11 patients are effective, and 10 patients are ineffective in 174 cases of men, the male cure rate is 87.9%, and the total effective rate is 94.3%; in 93 cases of women, 68 people are cured, 16 people are effective, and 9 people are not effective, the female cure rate is 73.1%, and the total effective rate is 90.3%.
In 174 cases of men in the control group, 110 cases are cured, 38 cases are effective, and 26 cases are ineffective, wherein the male cure rate is 63.2%, and the total effective rate is 85.1%; in 93 cases of women, 47 people are cured, 22 people are effective, and 24 people are not effective, the female cure rate is 50.5%, and the total effective rate is 74.2%.
As can be seen from table 2: the medicine is taken for 3 days, in a treatment group, 159 patients are cured, 7 patients are effective, and 8 patients are ineffective in 174 cases of men, the male cure rate is 91.4%, and the total effective rate is 95.4%; in 93 cases of women, 74 people are cured, 12 people are effective, and 7 people are ineffective, the female cure rate is 79.6%, and the total effective rate is 92.5%.
In 174 cases of men in the control group, 140 patients are cured, 16 patients are effective, and 18 patients are ineffective, the male cure rate is 80.1%, and the total effective rate is 89.7%; in 93 cases of women, 63 patients are cured, 14 patients are effective, and 16 patients are ineffective, the female cure rate is 67.7%, and the total effective rate is 82.8%.
As can be seen from table 3: after the medicine is taken for 4 days, in a treatment group, in 174 cases of men, 162 patients are cured, 5 patients are effective, and 7 patients are ineffective, the male cure rate is 93.1%, and the total effective rate is 96%; in 93 cases of women, 76 people are cured, 11 people are effective, and 6 people are not effective, the female cure rate is 81.7%, and the total effective rate is 93.5%.
In 174 cases of men in the control group, 142 patients are cured, 16 patients are effective, 16 patients are ineffective, the male cure rate is 81.6%, and the total effective rate is 90.8%; in 93 cases of women, 66 patients are cured, 14 effective patients are cured, and 13 ineffective patients are cured, the female cure rate is 70.1%, and the total effective rate is 86%.
From the above data it can be seen that:
(1) the effect of the traditional Chinese medicine formula is obviously better than that of the jaundice-removing oral liquid of a control group, and the cure rate and the total effective rate of the treatment group of the traditional Chinese medicine formula for both male and female infants are higher than those of the control group.
(2) The medicine has quick curative effect, and most patients take the medicine for 2 days to have obvious effect.
Examples of typical cases are:
case 1
The medicine is taken twice a day, after treatment for 3 days, clinical symptoms of the infant completely disappear, and no relapse occurs after 6 months of follow-up visit.
Case 2
The children are born for 28 days, yellow stain of the whole body, crying and anorexia, bleeding and detecting 138umol/L of bilirubin, the body-examination finds that the skin and sclera of the whole body of the children are yellow, and the yellow stain is not relieved after blue light treatment in a hospital for one week.
Case 3
The traditional Chinese medicine composition has the advantages that the traditional Chinese medicine composition is used for treating chronic hepatitis B, chronic hepatitis B and the like, the male is born for 25 days, jaundice of the whole body is not reduced, sleeping and restlessness and crying are caused, the curative effect of taking various Chinese and western patent medicines is not obvious, blue light is irradiated in a hospital, serum bilirubin is high in a blood drawing test, the yellow stain of the skin of the whole body disappears after the formula particles are taken.

Claims (10)

1. A traditional Chinese medicine formula for promoting rapid elimination of neonatal physiological jaundice is characterized in that: the feed comprises the following raw materials in parts by weight:
group A: 60-90 parts of oldenlandia diffusa, 60-90 parts of houttuynia cordata, 40-70 parts of selfheal, 80-120 parts of lysimachia christinae hance and 65-85 parts of hypericum japonicum;
group B: 40-70 parts of longhairy antenoron herb, 65-85 parts of gardenia jasminoides, 50-80 parts of cogongrass rhizome, 45-65 parts of plantain herb and 45-65 parts of abrus cantoniensis hance;
group C: 45-65 parts of wild chrysanthemum flower, 45-65 parts of lophatherum gracile, 40-65 parts of schisandra chinensis, 40-65 parts of isatis root and 20-60 parts of raw rhubarb;
group D: 60-90 parts of sedum sarmentosum, 45-65 parts of Chinese knotweed herb and 65-85 parts of linearstripe rabdosia herb;
wherein, the weight ratio of the group A, the group B, the group C and the group D is 1: 1: 1: 1.
2. the traditional Chinese medicine formula for promoting rapid elimination of neonatal physiological jaundice according to claim 1, wherein the traditional Chinese medicine formula comprises the following components in parts by weight: the feed comprises the following raw materials in parts by weight:
group A: 70-80 parts of oldenlandia diffusa, 70-80 parts of houttuynia cordata, 50-60 parts of selfheal, 90-100 parts of lysimachia christinae hance and 70-80 parts of hypericum japonicum;
group B: 50-60 parts of longhairy antenoron herb, 70-80 parts of gardenia jasminoides, 60-70 parts of cogongrass rhizome, 50-60 parts of plantain herb and 50-60 parts of abrus cantoniensis hance;
group C: 50-60 parts of wild chrysanthemum flower, 50-60 parts of lophatherum gracile, 50-60 parts of Chinese magnoliavine fruit, 50-60 parts of isatis root and 30-50 parts of raw rhubarb;
group D: 70-80 parts of stringy stonecrop herb, 50-60 parts of Chinese knotweed herb and 70-80 parts of linearstripe rabdosia herb;
wherein, the weight ratio of the group A, the group B, the group C and the group D is 1: 1: 1: 1.
3. the traditional Chinese medicine formula for promoting rapid elimination of neonatal physiological jaundice according to claim 2, wherein the traditional Chinese medicine formula comprises the following components in parts by weight: the feed comprises the following raw materials in parts by weight:
group A: 75 parts of oldenlandia diffusa, 75 parts of houttuynia cordata, 55 parts of selfheal, 95 parts of lysimachia christinae hance and 75 parts of hypericum japonicum;
group B: 55 parts of longhairy antenoron herb, 75 parts of gardenia jasminoides, 66 parts of cogongrass rhizome, 58 parts of plantain herb and 55 parts of abrus herb;
group C: 55 parts of wild chrysanthemum, 57 parts of lophatherum gracile, 55 parts of Chinese magnoliavine fruit, 58 parts of isatis root and 40 parts of raw rhubarb;
group D: 75 parts of stringy stonecrop herb, 55 parts of Chinese knotweed herb and 75 parts of linearstripe rabdosia herb;
wherein, the weight ratio of the group A, the group B, the group C and the group D is 1: 1: 1: 1.
4. a method of preparing a traditional Chinese medicine formulation for promoting rapid resolution of neonatal physiological jaundice, as claimed in any one of claims 1 to 3, wherein the preparation method comprises the following steps: the method comprises the following specific steps:
(1) weighing the raw materials according to the weight parts, crushing and uniformly mixing for later use;
(2) soaking in water, decocting to obtain filtrate and residue, and concentrating the filtrate to obtain soft extract;
(3) soaking the filter residue obtained in the step (2) in ethanol, performing reflux extraction, filtering to obtain a filtrate, and concentrating the filtrate into a thick paste;
(4) and (3) combining the thick paste obtained in the step (2) and the step (3), drying and crushing to obtain the composition.
5. The method for preparing a Chinese medicinal formulation for promoting rapid regression of neonatal physiological jaundice as claimed in claim 4, wherein the method comprises the following steps:
the specific process of soaking in step (2) is as follows: adding water 8-10 times the weight of the raw materials, and soaking for 4-6 hours.
6. The method for preparing a Chinese medicinal formulation for promoting rapid regression of neonatal physiological jaundice as claimed in claim 4, wherein the method comprises the following steps:
in the step (2), the decocting times are 2-3 times, and each time is 0.8-1.5 hours.
7. The method for preparing a Chinese medicinal formulation for promoting rapid regression of neonatal physiological jaundice as claimed in claim 4, wherein the method comprises the following steps:
in the step (2), the relative density of the thick paste at 60 ℃ is 1.20-1.25 g/ml.
8. The method for preparing a Chinese medicinal formulation for promoting rapid regression of neonatal physiological jaundice as claimed in claim 4, wherein the method comprises the following steps:
in the step (3), the adding amount of the ethanol is 7-9 times of the weight of the filter residue obtained in the step (2), the soaking time is 4-6 hours, and the concentration of the ethanol is 60-65%.
9. The method for preparing a Chinese medicinal formulation for promoting rapid regression of neonatal physiological jaundice as claimed in claim 4, wherein the method comprises the following steps:
in the step (3), the reflux extraction times are 2-3 times, and each time is 0.7-1 hour.
10. The method for preparing a Chinese medicinal formulation for promoting rapid regression of neonatal physiological jaundice as claimed in claim 4, wherein the method comprises the following steps:
in the step (3), the relative density of the thick paste at 60 ℃ is 1.20-1.25 g/ml.
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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103478349A (en) * 2013-08-30 2014-01-01 李娴 Zhuang herbal tea
CN103990081A (en) * 2014-06-17 2014-08-20 刘青振 Traditional Chinese medicine composition and application thereof in preparation of medicine for treating infant jaundice
CN105535584A (en) * 2015-12-23 2016-05-04 隆海凤 A bathing liquid for treating physiologic jaundice of newborns
CN110115753A (en) * 2019-06-28 2019-08-13 黄骥 The Chinese medicine preparation and preparation method thereof for treating hepatitis

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103478349A (en) * 2013-08-30 2014-01-01 李娴 Zhuang herbal tea
CN103990081A (en) * 2014-06-17 2014-08-20 刘青振 Traditional Chinese medicine composition and application thereof in preparation of medicine for treating infant jaundice
CN105535584A (en) * 2015-12-23 2016-05-04 隆海凤 A bathing liquid for treating physiologic jaundice of newborns
CN110115753A (en) * 2019-06-28 2019-08-13 黄骥 The Chinese medicine preparation and preparation method thereof for treating hepatitis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
王玲: "自拟逐瘀降黄汤治疗新生儿湿热瘀滞型黄疸90例临床观察", 《中医临床研究》 *

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Application publication date: 20200811