CN111512159A - 结核诊断方法 - Google Patents

结核诊断方法 Download PDF

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Publication number
CN111512159A
CN111512159A CN201880083123.2A CN201880083123A CN111512159A CN 111512159 A CN111512159 A CN 111512159A CN 201880083123 A CN201880083123 A CN 201880083123A CN 111512159 A CN111512159 A CN 111512159A
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CN
China
Prior art keywords
tuberculosis
antigen
antibody
treating
diagnostic method
Prior art date
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Pending
Application number
CN201880083123.2A
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English (en)
Chinese (zh)
Inventor
金银京
李宣嬉
柳承范
孙美进
金和中
金保罗
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sugentech Inc
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Sugentech Inc
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Publication date
Application filed by Sugentech Inc filed Critical Sugentech Inc
Publication of CN111512159A publication Critical patent/CN111512159A/zh
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/5375Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by changing the physical or chemical properties of the medium or immunochemicals, e.g. temperature, density, pH, partitioning
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/04Mycobacterium, e.g. Mycobacterium tuberculosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40Concentrating samples
    • G01N1/4044Concentrating samples by chemical techniques; Digestion; Chemical decomposition
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54386Analytical elements
    • G01N33/54387Immunochromatographic test strips
    • G01N33/54388Immunochromatographic test strips based on lateral flow
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/5695Mycobacteria
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/35Assays involving biological materials from specific organisms or of a specific nature from bacteria from Mycobacteriaceae (F)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00Immunoassays for the detection of microorganisms
    • G01N2469/10Detection of antigens from microorganism in sample from host
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2470/00Immunochemical assays or immunoassays characterised by the reaction format or reaction type
    • G01N2470/04Sandwich assay format
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/26Infectious diseases, e.g. generalised sepsis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
CN201880083123.2A 2017-12-22 2018-12-21 结核诊断方法 Pending CN111512159A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2017-0178159 2017-12-22
KR20170178159 2017-12-22
PCT/KR2018/016434 WO2019125034A1 (fr) 2017-12-22 2018-12-21 Méthode de diagnostic de la tuberculose

Publications (1)

Publication Number Publication Date
CN111512159A true CN111512159A (zh) 2020-08-07

Family

ID=66993586

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201880083123.2A Pending CN111512159A (zh) 2017-12-22 2018-12-21 结核诊断方法

Country Status (6)

Country Link
US (1) US20210072235A1 (fr)
EP (1) EP3726219A4 (fr)
JP (1) JP2021508836A (fr)
KR (1) KR20190076897A (fr)
CN (1) CN111512159A (fr)
WO (1) WO2019125034A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3164027A1 (fr) * 2019-12-09 2021-06-17 Versiti Blood Research Institute Foundation Inc. Constructions bcg car et leurs procedes de preparation et d'utilisation
KR102351951B1 (ko) * 2020-05-06 2022-01-17 한국원자력연구원 결핵균을 검출하는 방법
KR20230102652A (ko) 2021-12-30 2023-07-07 한국화학연구원 결핵균 항원 또는 항체 검출용 산화아연 나노선 어레이의 제조방법

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002062299A (ja) * 2000-08-24 2002-02-28 Kyowa Medex Co Ltd 結核菌の検出方法及び試薬
CN1694725A (zh) * 2001-08-02 2005-11-09 纽约大学 肽在早期检测分枝杆菌疾病中的应用
JPWO2009084481A1 (ja) * 2007-12-28 2011-05-19 株式会社ビーエル 結核菌群の免疫検出法
CN103864907A (zh) * 2012-12-18 2014-06-18 中国医学科学院病原生物学研究所 用于结核病诊断的蛋白以及试剂盒

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5384240A (en) * 1992-11-25 1995-01-24 Akzo Nobel, N.V. Base dissociation assay
US20090280474A1 (en) * 2008-05-08 2009-11-12 Abbott Laboratories Method for detecting a virus
US8450076B2 (en) * 2008-09-11 2013-05-28 Institut Pasteur Monitoring and inhibiting human immunodeficiency virus infection by modulating HMGB1 dependent triggering of HIV-1 replication and persistence
SG10201600531TA (en) * 2011-01-24 2016-02-26 Univ Singapore Pathogenic mycobacteria-derived mannose-capped lipoarabinomannan antigen binding proteins
KR101707291B1 (ko) * 2012-02-29 2017-02-15 오쓰까 세이야꾸 가부시키가이샤 항리포아라비노만난 항체 및 당해 항체를 사용한 항산균증의 이뮤노어세이
US20150355178A1 (en) * 2012-09-04 2015-12-10 Mbio Diagnostics, Inc. System and method for improving biomarker assay
KR101524109B1 (ko) 2014-03-14 2015-06-02 충남대학교산학협력단 결핵균 특이항원에 대한 항체가 결합되어 있는 나노­바이오센서 및 이를 이용한 결핵균 검출진단법
WO2016130638A1 (fr) * 2015-02-10 2016-08-18 University Of Utah Research Foundation Procédés de détection d'analytes et de diagnostic de la tuberculose
KR20170011200A (ko) * 2015-07-22 2017-02-02 사단법인대한결핵협회 결핵 특이 항원의 융합 단백질, 이의 효율적 생산방법 및 이의 용도

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002062299A (ja) * 2000-08-24 2002-02-28 Kyowa Medex Co Ltd 結核菌の検出方法及び試薬
CN1694725A (zh) * 2001-08-02 2005-11-09 纽约大学 肽在早期检测分枝杆菌疾病中的应用
JPWO2009084481A1 (ja) * 2007-12-28 2011-05-19 株式会社ビーエル 結核菌群の免疫検出法
CN103864907A (zh) * 2012-12-18 2014-06-18 中国医学科学院病原生物学研究所 用于结核病诊断的蛋白以及试剂盒

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
A.G.KHOMENKO,ETC,: ""Serodiagnosis of tuberculosis: detection of mycobacterial antibodies and antigens"", <TUBERCLE AND LUNG DISEASE> *

Also Published As

Publication number Publication date
WO2019125034A1 (fr) 2019-06-27
EP3726219A1 (fr) 2020-10-21
JP2021508836A (ja) 2021-03-11
US20210072235A1 (en) 2021-03-11
KR20190076897A (ko) 2019-07-02
EP3726219A4 (fr) 2021-09-29

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Application publication date: 20200807