CN111466875A

CN111466875A - Rotary diffusion optical imaging system

Info

Publication number: CN111466875A
Application number: CN202010172373.2A
Authority: CN
Inventors: 朱守平; 陈睿博; 王艺涵; 马骋; 赵婧
Original assignee: Xidian University
Current assignee: Xidian University
Priority date: 2020-03-12
Filing date: 2020-03-12
Publication date: 2020-07-31
Anticipated expiration: 2040-03-12
Also published as: CN111466875B

Abstract

The invention discloses a rotary type diffusion optical imaging system which comprises a light source unit, a detection unit, a bearing device with an imaging cavity, a rotatable sleeve device and a data acquisition unit, wherein the light source unit comprises a plurality of light-emitting sources, the detection unit comprises a plurality of detectors, the sleeve device comprises a sleeve, N rows of through holes and M columns of through holes are arranged on the sleeve, a light-emitting source is correspondingly arranged in each through hole in the mth column, one detector is correspondingly arranged in each through hole except the mth column, and the sleeve is sleeved with the imaging cavity. The rotary diffusion optical imaging system provided by the invention does not use optical fibers for light conduction any more, but adopts a mode that a light source and a detector are tightly attached to a measured object to realize excitation and reception, thereby greatly reducing the complexity and the cost of the system, simultaneously improving the consistency of each channel and the signal to noise ratio of an acquired signal, realizing data acquisition and reconstruction to further research DOT imaging, and being convenient for applying the technology to mammary gland imaging.

Description

Rotary diffusion optical imaging system

Technical Field

The invention belongs to the technical field of imaging, and particularly relates to a rotary type diffusion optical imaging system.

Background

Diffusion Optical Tomography (DOT) has specificity, dynamics and sensitivity to changes in tissue function, and also has the advantages of safe and reliable use, low cost and the like. Therefore, the near infrared diffusion optical tomography technology has wide application potential and research value. Currently, the main application aspects of DOT technology are brain function imaging, breast imaging, and the like. For breast imaging, when a tissue is cancerated, due to the enrichment of blood vessels and a higher cellular metabolism level, the region presents the characteristic of enriching blood and lacking oxygen, so that the region has stronger light absorption compared with a normal tissue, and therefore, the DOT technology can obtain the difference of physiological parameters between a tumor tissue and the normal tissue by utilizing the imaging of endogenous substances such as hemoglobin, water, lipid and the like in a breast.

Referring to fig. 1, fig. 1 provides an imaging system, which mainly includes a light source system, an attenuator, a collimator, an electric rotating table, an electric elevating table, a source optical fiber, a detection optical fiber, an optical switch, an experimental phantom, a filter wheel, a PMT (Photomultiplier Tube), and a counting module. The light source system provides a stable continuous wave light source with a wavelength of 660nm, the intensity of which is finely adjusted by an attenuator. A light source is coupled into a light source optical fiber with the core diameter of 62.5 mu m and the numerical aperture of 0.22, and the light source optical fiber is collimated by a collimator and then enters the surface of the imitation body; referring to fig. 2, 8 detection optical fibers uniformly distributed between 101.25 ° and 258.75 ° on the same horizontal plane of the light source collect diffused light at corresponding detection positions, and the diffused light passes through 8: 1, switching an optical switch and respectively leading in a motor to drive a filter wheel; the photon counting system detects the optical signals after the optical filtering processing to respectively obtain photon number information of excitation light and fluorescence at different detection positions, and the system adopts a rotating platform to rotate the imitation body according to a mode similar to CT (Computed Tomography) so as to realize the scanning of 0-360 degrees of the imitation body and acquire the photon number information under a plurality of light source incidence angles.

However, the system structure is too complex, light generated by the light source can reach the imaging cavity through the optical fiber, the attenuator and the collimator, and simultaneously emergent light signals can reach the detector through the optical fiber, the optical switch, the collimator and the filter wheel. Light passes through a plurality of devices in the whole process, so that great light loss is difficult to avoid. And poor system stability can be caused due to more system devices which are difficult to avoid. In addition, the system uses PMT as a photoelectric detection device, is expensive and needs strict light-shielding conditions. In addition, because the system uses a single PMT for data receiving, although the system cost can be reduced, the data acquisition time is increased, and the system efficiency is reduced.

Disclosure of Invention

In order to solve the above problems in the prior art, the present invention provides a rotary type diffusion optical imaging system. The technical problem to be solved by the invention is realized by the following technical scheme:

a rotary diffusion optical imaging system comprises a light source unit, a detection unit, a bearing device with an imaging cavity, a rotatable sleeve device and a data acquisition unit, wherein the light source unit comprises a plurality of light-emitting sources, the detection unit comprises a plurality of detectors, the sleeve device comprises a sleeve, N rows of through holes M columns are arranged on the sleeve, one light-emitting source is correspondingly arranged in each through hole of the mth column, one detector is correspondingly arranged in each through hole except the through holes of the mth column, the imaging cavity is sleeved with the sleeve,

the light source unit is used for providing optical signals in a steady state mode or a frequency domain mode for an object to be detected in the imaging cavity;

the detection unit is used for detecting the optical signal penetrating through the object to be detected and converting the optical signal into an electric signal;

the data acquisition unit is used for acquiring the electric signal and converting the electric signal into a digital signal.

In one embodiment of the invention, the light emitting source comprises a laser diode.

In one embodiment of the invention, the detector comprises a silicon photomultiplier tube.

In one embodiment of the present invention, the device further comprises a modulation signal generating unit, the modulation signal generating unit is connected to the light source unit, the modulation signal generating unit comprises a DDS module, a first signal generating module, a second signal generating module, a first signal output module, and a second signal output module, wherein,

the DDS module is used for providing a sine signal;

the first signal generation module is connected with the DDS module and used for generating a first frequency signal or a direct current signal by using the sinusoidal signal;

the second signal generation module is connected with the DDS module and is used for generating a second frequency signal by using the sinusoidal signal, and the frequency of the second frequency signal is greater than that of the first frequency signal;

the first signal output module is connected with the first signal generation module and used for outputting a direct current signal generated by the first signal generation module or converting the first frequency signal into a first square wave signal and controlling the modulation depth and the modulation size of the first square wave signal;

the second signal output module is connected to the second signal generation module and is configured to convert the second frequency signal into a second square wave signal and control the modulation depth and magnitude of the second square wave signal.

In an embodiment of the present invention, the first signal generating module includes a resistor R1, a resistor R3, a transformer L1, a capacitor C15, a capacitor C16, a capacitor C17, a capacitor C18, a capacitor C19, a capacitor C20, a capacitor C21, a capacitor C22, a capacitor C23, a capacitor C24, a capacitor C25, an inductor L2, an inductor L20, and an inductor L21, wherein,

the pin 30 of the DDS module is connected to the first end of the resistor R and the port 1 of the transformer 1, the pin 29 of the DDS module is connected to the first end of the resistor R and the port 3 of the transformer 1, the second end of the resistor R and the second end of the resistor R are connected to the port 2 and the power end of the transformer 01, the port 4 of the transformer 1 is connected to the ground terminal, the port 6 of the transformer 1 is connected to the first end of the capacitor C, the first end of the capacitor C and the first end of the inductor 2, the second end of the capacitor C and the second end of the capacitor C are both connected to the ground terminal, the second end of the capacitor C and the second end of the inductor 2 are both connected to the first end of the capacitor C, the first end of the capacitor C and the first end of the inductor 20, the second end of the capacitor C and the second end of the capacitor C are both connected to the ground terminal, the second end of the capacitor C and the second end of the capacitor C21 are both connected to the ground terminal of the capacitor C and the second end of the capacitor C, the capacitor C and the second end of the inductor 2 are both connected to the ground terminal.

In an embodiment of the present invention, the first signal output module includes a converter FB13, a converter FB15, a converter FB17, a capacitor C66, a capacitor C67, a capacitor C68, a capacitor C74, a capacitor C75, a capacitor C76, a capacitor C77, a capacitor C78, a capacitor C81, a capacitor C82, a resistor R23, a sliding resistor R24, a resistor R25, a resistor R26, a resistor R27, a resistor R28, a resistor R34, a resistor R35, a resistor R36, a resistor R37, a resistor R38, a resistor R43, a resistor R44, a resistor R45, a resistor R46, a resistor 47, a triode U77, a first chip, a second chip, and an IPEX connector J28, wherein,

a first end of the converter FB13 is connected to a power supply terminal, a second end of the converter FB13 is connected to a first end of the capacitor C66, a first end of the capacitor C67, a first end of the resistor R23, a pin 1 and a pin 8 of the first chip, a second end of the capacitor C66 and a second end of the capacitor C67 are both connected to a ground terminal, a second end of the resistor R23 is connected to a sliding end of the resistor R24, a first end of the capacitor C68 and a pin 2 of the first chip, a first end of the sliding resistor R24 is connected to a first end of the resistor R25, a second end of the resistor R25 and a second end of the capacitor C68 are connected to the ground terminal, a pin 3 of the first chip is connected to the first end of the resistor R26, a second end of the resistor R26 is connected to the first port, a pin 4 of the first end of the first chip is connected to a first end of the resistor R27, and a second end of the resistor R27 is connected to the ground terminal, the pin 5 of the first chip is connected with the first end of the resistor R28, the second end of the resistor R28, the pin 6 of the first chip and the second end of the resistor R28 are connected with the ground terminal, and the pin 7 of the first chip is connected with the third port;

a first end of the resistor R37 is connected to the first port, a second end of the resistor R37 is connected to the first end of the resistor R36 and the third port, a second end of the resistor R36 is connected to pin 4 of the second chip, a first end of the resistor R38 and a first end of the capacitor C78, a second end of the resistor R38 and a second end of the capacitor C78 are connected to pin 1 and a fourth port of the second chip, pin 2 of the second chip is connected to the first end of the capacitor C76 and the first end of the capacitor C77, the second end of the capacitor C76 and the second end of the capacitor C77 are connected to ground, pin 3 of the second chip is connected to the first end of the resistor R34 and the first end of the resistor R35, the second end of the resistor R35 is connected to ground, pin 5 of the second chip is connected to the first end of the capacitor C74 and the first end of the capacitor C75, the second end of the capacitor C74 and the second end of the capacitor C75 are connected to the ground terminal;

a first end of the converter FB15 is connected to a power supply terminal, a first end of the converter FB17 is connected to a power supply terminal, a second end of the converter FB15 and a second end of the converter FB17 are connected to a first end of the capacitor C81, a first end of the capacitor C82 and a first end of the resistor R43, a second end of the capacitor C81 and a second end of the capacitor C82 are connected to a ground terminal, a second end of the resistor R43 is connected to a collector of the transistor U77, a first end of the resistor R44 and a first end of the resistor R46 are connected to the fourth port, a first end of the resistor R44 and a first end of the resistor R46 are further connected to a first end of the resistor R45, a second end of the resistor R44 is connected to a base of the transistor U77, a second end of the resistor R46 and an emitter of the transistor U77 are connected to a first end of the resistor R47, a second end of the resistor R47 is connected to an ipj 28 ex 1 port of the transistor U539, port 2 and port 3 of the IPEX connector J28 are connected to ground.

In an embodiment of the present invention, the second signal generating module includes a resistor R4, a resistor R5, a transformer L6, a capacitor C26, a capacitor C27, a capacitor C28, a capacitor C29, a capacitor C30, a capacitor C31, a capacitor C32, a capacitor C33, a capacitor C34, a capacitor C35, a capacitor C36, an inductor L22, an inductor L23, and an inductor L24, wherein,

a pin 36 of the DDS module is connected to the first end of the resistor R and the port 1 of the transformer 6, a pin 35 of the DDS module is connected to the first end of the resistor R and the port 3 of the transformer 6, the second end of the resistor R and the second end of the resistor R are connected to the port 2 and the power end of the transformer 06, the port 4 of the transformer 6 is connected to the ground terminal, the port 6 of the transformer 6 is connected to the first end of the capacitor C, the first end of the capacitor C and the first end of the inductor 22, the second end of the capacitor C and the second end of the capacitor C are both connected to the ground terminal, the second end of the capacitor C and the second end of the inductor 22 are both connected to the first end of the capacitor C, the first end of the capacitor C and the first end of the inductor 23, the second end of the capacitor C and the second end of the capacitor C are both connected to the ground terminal, the second end of the capacitor C and the second end of the capacitor C are both connected to the first end of the capacitor C, the second end of the capacitor C and the second end of the inductor C24, the second end of the capacitor C are both connected to the ground terminal of the capacitor C, and the second end of the capacitor C are both connected to the capacitor C, and the second end of the capacitor C, and the second.

In an embodiment of the present invention, the second signal output module includes a converter FB12, a converter FB14, a converter FB16, a capacitor C63, a capacitor C64, a capacitor C65, a capacitor C69, a capacitor C70, a capacitor C71, a capacitor C72, a capacitor C73, a capacitor C79, a capacitor C80, a sliding resistor R17, a resistor R18, a resistor R19, a resistor R20, a resistor R21, a resistor R22, a resistor R29, a resistor R30, a resistor R31, a resistor R32, a resistor R33, a resistor R39, a resistor R40, a resistor R41, a resistor R42, a triode U5, a third chip, a fourth chip, and an IPEX connector J27, wherein,

a first end of the converter FB12 is connected to a power supply terminal, a second end of the converter FB12 is connected to a first end of the capacitor C63, a first end of the capacitor C64, a first end of the resistor R18, a pin 1 and a pin 8 of the third chip, a second end of the capacitor C63 and a second end of the capacitor C64 are both connected to a ground terminal, a second end of the resistor R18 is connected to a sliding end of the resistor R17, a first end of the capacitor C65 and a pin 2 of the third chip, a first end of the sliding resistor R17 is connected to a first end of the resistor R19, a second end of the resistor R19 and a second end of the capacitor C65 are connected to the ground terminal, a pin 3 of the third chip is connected to the first end of the resistor R20, a second end of the resistor R20 is connected to the second port, a pin 4 of the third chip is connected to the first end of the resistor R21, and a second end of the resistor R21 is connected to the ground terminal, a pin 5 of the third chip is connected with a first end of the resistor R22, a second end of the resistor R22, a pin 6 of the third chip and a second end of the resistor R22 are connected with a ground terminal, and a pin 7 of the third chip is connected with a fifth port;

the first end of the resistor R32 is connected to the second port, the second end of the resistor R32 is connected to the first end of the resistor R31 and the fifth port, the second end of the resistor R31 is connected to the pin 4 of the fourth chip, the first end of the resistor R33 and the first end of the capacitor C73, the second end of the resistor R33 and the second end of the capacitor C73 are connected to the pin 1 and the sixth port of the fourth chip, the pin 2 of the fourth chip is connected to the first end of the capacitor C71 and the first end of the capacitor C72, the second end of the capacitor C71 and the second end of the capacitor C72 are connected to the ground, the pin 3 of the fourth chip is connected to the first end of the resistor R29 and the first end of the resistor R30, the second end of the resistor R29 is connected to the ground, the pin 5 of the fourth chip is connected to the first end of the capacitor C69 and the first end of the capacitor C70, the second end of the capacitor C69 and the second end of the capacitor C70 are connected to the ground terminal;

a first end of the converter FB14 is connected to a power supply terminal, a first end of the converter FB16 is connected to the power supply terminal, a second end of the converter FB14 and a second end of the converter FB16 are connected to a first end of the capacitor C79, a first end of the capacitor C80 and a first end of the resistor R39, a second end of the capacitor C79 and a second end of the capacitor C80 are connected to a ground terminal, a second end of the resistor R39 is connected to a collector of the transistor U5, a first end of the resistor R40 and a first end of the resistor R41 are connected to the sixth port, a second end of the resistor R40 is connected to a base of the transistor U5, a second end of the resistor R41 and an emitter of the transistor U5 are connected to a first end of the resistor R42, a second end of the resistor R42 is connected to a port 1 of the IPEX junction J27, and a port 27 and a port J3 of the IPEX junction J2 are connected to the ground.

In one embodiment of the present invention, the light source unit includes a gating module including a capacitor C83, a capacitor C84, a resistor R48, a resistor R49, a resistor R50, a plurality of light source connection modules, a fifth chip, a sixth chip, and an IPEX junction J29, each of the light source connection modules includes a resistor R51, wherein,

the

ports

2 and 3 of the IPEX connector J29 are connected to a ground terminal, the port 1 of the IPEX connector J29 is connected to the first signal output module and the second signal output module, the port 1 of the IPEX connector J29 is further connected to the first end of the resistor R49, the second end of the resistor R49 is connected to a seventh port, the seventh port is connected to anodes of all the laser diodes, the cathode of each laser diode is connected to the first end of the resistor R51, the second end of the resistor R51 is connected to an eighth port, all the eighth ports are correspondingly connected to pins of the fifth chip, the pin 16 of the fifth chip is connected to the first end of the capacitor C83 and the first end of the capacitor C84, the second end of the capacitor C83 and the second end of the capacitor C84 are connected to a ground terminal, and the pin 5 of the fifth chip is connected to the first end of the resistor R48, the second end of the resistor R48 is connected with a ground terminal, the control pins of the fifth chip are correspondingly connected with the control pins of the sixth chip, the pin 5 of the sixth chip is connected with the first end of the resistor R50, and the second end of the resistor R50 is connected with the seventh port.

In an embodiment of the invention, the detection unit includes a capacitor C85, a capacitor C86, a capacitor C87, a capacitor C88, a capacitor C89, a capacitor C90, a capacitor C91, a capacitor C92, a capacitor C93, a capacitor C94, a plurality of capacitors C95, a plurality of capacitors C96, a resistor R52, a resistor R53, a sliding resistor R54, a seventh chip, an eighth chip, a plurality of amplification modules, a plurality of IPEX connectors J1, the amplification modules include a capacitor C97, a capacitor C98, a capacitor C99, a capacitor C100, a capacitor C101, a resistor 55 and a ninth chip, wherein,

a first end of the capacitor C85 and a first end of the capacitor C86 are connected to a power supply terminal, a pin 1 and a pin 2 of the seventh chip, a second end of the capacitor C85 and a second end of the capacitor C86 are connected to a ground terminal, a first end of the capacitor C87 is connected to a pin 5 and a pin 6 of the seventh chip, a second end of the capacitor C87 is connected to the ground terminal, a first end of the capacitor C88 is connected to a pin 7 and a pin 8 of the seventh chip, and a second end of the capacitor C88 is connected to the ground terminal;

the first end of the capacitor C89, the first end of the capacitor C90, the first end of the capacitor C91, the first end of the capacitor C85, and the first end of the capacitor C86 are commonly connected to a same power supply terminal, the first end of the capacitor C89, the first end of the capacitor C90, and the first end of the capacitor C91 are further connected to the pin 1, the pin 2, the pin 3, and the pin 9 of the eighth chip, the second end of the capacitor C89, the second end of the capacitor C90, and the second end of the capacitor C91 are connected to the ground terminal, the first end of the capacitor C92, the first end of the capacitor C93, and the first end of the capacitor C94 are connected to the power supply terminal, the pin 7 and the pin 8 of the eighth chip, the first end of the capacitor C92, the first end of the capacitor C93, and the first end of the capacitor C94 are further connected to the sliding end of the sliding resistor R54, the second end of the capacitor C92, and the second end of the capacitor C93, A second end of the capacitor C94 is connected to a ground terminal, a pin 6 of the eighth chip is connected to a first end of the resistor R52 and a first end of the resistor R53, a second end of the resistor R52 is connected to the sliding resistor R54, and a second end of the resistor R53 is connected to the ground terminal;

pin 1 of each silicon photomultiplier is connected to a first end of a capacitor C95 and a first end of a capacitor C96, a first end of a capacitor C95 and a first end of a capacitor C96 are connected to a same power supply terminal, a first end of a capacitor C92, a first end of a capacitor C93 and a first end of a capacitor C94 are connected to a ground terminal, a second end of a capacitor C95 and a second end of a capacitor C96 are connected to a ground terminal, and pin 3 of the silicon photomultiplier is connected to an eighth port;

each of the eighth ports is correspondingly connected to a pin 4 of the ninth chip, a first end of the resistor 55, and a first end of the capacitor C101, a second end of the resistor 55 and a second end of the capacitor C101 are connected to a pin 1 and a ninth port of the ninth chip, a first end of the capacitor C97 and a first end of the capacitor C98 are connected to a pin 5 of the ninth chip, a second end of the capacitor C97 and a second end of the capacitor C98 are connected to a ground terminal, a first end of the capacitor C99 and a first end of the capacitor C100 are connected to a pin 2 of the ninth chip, a second end of the capacitor C99 and a second end of the capacitor C100 are connected to a ground terminal, each of the ninth ports is correspondingly connected to a port 1 of the IPEX connector J1, and port 2 and port 3 of the IPEX connector J1 are connected to the ground terminal.

The invention has the beneficial effects that:

the rotary diffusion optical imaging system provided by the invention does not use optical fibers for light conduction any more, but adopts a mode that a light source and a detector are tightly attached to a measured object to realize excitation and reception, thereby greatly reducing the complexity and the cost of the system, simultaneously improving the consistency of each channel and the signal to noise ratio of an acquired signal, realizing data acquisition and reconstruction to further research DOT imaging, and being convenient for applying the technology to mammary gland imaging.

The present invention will be described in further detail with reference to the accompanying drawings and examples.

Drawings

FIG. 1 is a schematic illustration of an imaging system provided in the prior art;

FIG. 2 is a schematic diagram of a prior art detection plane based imaging system of FIG. 1;

FIG. 3 is a schematic diagram of a rotary diffusion optical imaging system according to an embodiment of the present invention;

FIG. 4 is a schematic view of a carrying device according to an embodiment of the present invention;

FIG. 5 is a schematic view of a cartridge device according to an embodiment of the present invention;

fig. 6 is a schematic diagram of a modulation signal generating unit according to an embodiment of the present invention;

FIG. 7 is a schematic diagram of another modulation signal generating unit according to an embodiment of the present invention;

fig. 8 is a schematic diagram of a first signal conversion module according to an embodiment of the present invention;

FIG. 9 is a schematic diagram of a first amplification module provided by embodiments of the present invention;

FIG. 10 is a diagram of a first signal output module according to an embodiment of the present invention;

fig. 11 is a schematic diagram of a second signal conversion module according to an embodiment of the present invention;

FIG. 12 is a schematic diagram of a second amplification module provided in accordance with embodiments of the present invention;

FIG. 13 is a diagram of a second signal output module according to an embodiment of the present invention;

fig. 14a to 14d are schematic diagrams of a signal interface module, a light source communication module, a light source gating module, and a control module provided in sequence according to an embodiment of the present invention;

15a-15e are schematic diagrams of a power supply access module, a gain voltage module, a detector switch-on module, an amplification module, and a detection output module provided in sequence according to an embodiment of the invention;

FIG. 16 is a schematic illustration of an imaging process provided by an embodiment of the invention;

FIG. 17 is a schematic diagram of sampling points within a period according to an embodiment of the present invention;

fig. 18a to 18c are schematic diagrams of a sampling point of a signal in a 1 st period, a sampling point of a signal in an 80 th period, and a sampling point of a signal in a 561 th period, which are provided in sequence according to an embodiment of the present invention.

Detailed Description

The present invention will be described in further detail with reference to specific examples, but the embodiments of the present invention are not limited thereto.

Example one

Referring to fig. 3, fig. 3 is a schematic view of a rotational diffusion optical imaging system according to an embodiment of the present invention. The embodiment provides a rotary type diffusion optical imaging system, which comprises a light source unit, a detection unit, a bearing device 10 with an imaging cavity 101, a rotatable sleeve device 20 and a data acquisition unit, wherein the light source unit comprises a plurality of light-emitting sources, the detection unit comprises a plurality of detectors, the sleeve device 20 comprises a sleeve 201, the sleeve 201 is provided with N rows and M columns of through holes 202, each through hole 202 in the mth column is correspondingly provided with a light-emitting source, each through hole 202 except the mth column is correspondingly provided with a detector, the sleeve 201 is sleeved with the imaging cavity 101, M is more than or equal to 1 and less than or equal to M, and the light source unit is used for providing optical signals in a steady state mode or a frequency domain mode for an object to be detected in the imaging cavity 101; the detection unit is used for detecting an optical signal passing through the object to be detected and converting the optical signal into an electrical signal; the data acquisition unit is used for acquiring the electric signal and converting the electric signal into a digital signal.

Preferably, the light source comprises a laser diode and the detector comprises a silicon photomultiplier tube.

Generally, the diffuse optical imaging system can be divided into three modes, namely a steady state mode, a frequency domain mode and a time domain mode, the present embodiment mainly aims at the steady state mode and the frequency domain mode, the light source unit of the present embodiment is used for providing an optical signal to an object to be measured (i.e. a breast), the light source unit can provide an optical signal in the steady state mode and also can provide an optical signal in the frequency domain mode, the detection unit can detect the optical signal passing through the object to be measured and can convert the optical signal into an electrical signal, the rotary diffuse optical imaging system of the present embodiment further includes a carrying device 10, the carrying device 10 has an imaging cavity 101, the imaging cavity 101 has a cavity, matching fluid with certain optical parameters can be placed in the cavity, a connecting base 102 is further disposed at the bottom end of the carrying device 10, the connecting base 102 is used for fixing the carrying device 10, for example, the connecting base 102 can be fixedly mounted on an optical platform by means of bolts, when an object to be detected needs to be imaged, the connecting base 102 of the bearing device 10 can be fixed on an optical platform, and the object to be detected is placed in the imaging cavity 101 filled with matching fluid; the rotary type diffusion optical imaging system of the embodiment further comprises a rotatable sleeve device 20, the sleeve device 20 further comprises a sleeve 201, the sleeve 201 is sleeved outside the imaging cavity 101, the lower end of the sleeve device 20 is further provided with a base 203, the lower end of the base 203 can be connected with a rotary table, the rotary table is connected with a motor capable of driving the rotary table to rotate, when the sleeve device 20 is required to rotate, the rotary table can be driven to rotate through the motor, and therefore the sleeve device 20 is driven to rotate.

In the present embodiment, N rows by M columns of through holes 202 are arranged on the sleeve 201, where N and M may be set according to actual requirements, N and M should be integers greater than 1, for example, N is 6, M is 24, a distance between two rows of through holes 202 is, for example, 15mm, and a distance between two columns of through holes 202 is, for example, 13mm, in the present embodiment, a laser diode is correspondingly arranged in each through hole 202 in one column (for example, M columns) of through holes 202 in the M columns, and a wavelength of the laser diode may be in a range of 600 to 900 nm. In addition, a silicon photomultiplier is disposed in each through hole 202 except the m-th column, and during imaging, the sleeve 201 rotates around the imaging cavity 101 for a certain angle each time, and then data is acquired once until 360 ° data acquisition is completed, for example, 17 positions can be acquired in each acquisition in the present rotary type diffusion optical imaging system. In the embodiment, a detection array is formed by using silicon photomultiplier tubes, so that the optical signals passing through the object to be detected are received and converted into electric signals. The silicon photomultiplier is a novel photoelectric detector, has the characteristics of strong adaptability, high gain, low cost, good stability and the like, all the silicon photomultipliers work simultaneously when the rotation type diffusion optical imaging system is used for measurement, and the data acquisition unit synchronously finishes data acquisition. In order to enable the laser diode and the silicon photomultiplier to be tightly attached to the sleeve 201, the laser diode, the silicon photomultiplier and related circuits thereof can be integrated on a flexible Printed Circuit Board (PCB), and the flexible PCB has the characteristics of small thickness and good plasticity, so that the designed detection unit has the characteristics of light volume and high plasticity, and the laser diode, the silicon photomultiplier and related circuits thereof can be tightly attached to the sleeve 201, so that light loss is reduced compared with a hard PCB, and the signal-to-noise ratio and the imaging quality of the system are improved.

The rotary type diffusion optical imaging system of this embodiment further includes a modulation signal generating unit, the modulation signal generating unit is connected to the light source unit, the modulation signal generating unit is used for providing a modulation signal to the laser diode, referring to fig. 6, the modulation signal generating unit includes a DDS (Direct Digital Synthesis, Direct Digital frequency Synthesis) module, a first signal generating module, a second signal generating module, a first signal output module, and a second signal output module, wherein,

a DDS module for providing a sinusoidal signal;

the first signal generation module is connected with the DDS module and used for generating a first frequency signal or a direct current signal by utilizing a sinusoidal signal;

the first signal generation module is connected with the DDS module and is used for generating a first frequency signal by utilizing a sinusoidal signal;

the first signal output module is connected with the first signal generation module and used for outputting a direct current signal of the first signal generation module or converting a first frequency signal into a first square wave signal and controlling the modulation depth and the modulation size of the first square wave signal;

and the second signal output module is connected with the second signal generation module and used for converting the second frequency signal into a second square wave signal and controlling the modulation depth and the modulation size of the second square wave signal.

That is to say, the first signal generating module may generate a first frequency signal or a direct current signal by using a sine wave provided by the DDS module, the second signal generating module may generate a second frequency signal by using the sine wave provided by the DDS module, and a frequency of the second frequency signal is greater than that of the first frequency signal, so that the first frequency signal and the second frequency signal may provide modulation signals with different frequencies, and the modulation signals with different frequencies may be used to implement detection in a frequency domain mode, and the first signal generating module may also generate a direct current signal, so that detection in a steady state mode may be implemented in a direct current signal. The first signal output module is configured to convert a first frequency signal or a direct current signal into a first square wave signal, and control the modulation depth and the modulation size of the first square wave signal by using the first signal output module, that is, modulate the peak value, the maximum value, and the minimum value of the first square wave signal, and the second signal output module is configured to convert a second frequency signal into a second square wave signal, and control the modulation depth and the modulation size of the second square wave signal by using the second signal output module, that is, modulate the peak value, the maximum value, and the minimum value of the second square wave signal, for example, the frequency corresponding to the first frequency signal is 200Hz, and the frequency corresponding to the second frequency signal is 30 MHz.

Preferably, the acquisition module is an acquisition card, such as a multi-path high-speed acquisition card.

Specifically, referring to fig. 7, the first signal generating module includes a resistor R, a transformer 1, a capacitor C, an inductor 2, an inductor 020, and an inductor 121, wherein a pin 30 (pin CH _ IOUT) of the DDS module is connected to a first end of the resistor R and a port 1 of the transformer 21, a pin 29 (pin CH _ IOUT) of the DDS module is connected to a first end of the resistor R and a port 3 of the transformer 31, a second end of the resistor R and a second end of the resistor R are connected to a port 2 and a power supply terminal of the transformer 41, a port 4 of the transformer 1 is connected to a ground terminal, a port 6 of the transformer 1 is connected to the first end of the capacitor C, the first end of the capacitor C and the first end of the inductor 2, the second end of the capacitor C and the second end of the capacitor C are connected to the ground terminal, the second end of the capacitor C and the second end of the inductor C are connected to the ground terminal, the first end of the capacitor C and the second end of the capacitor C, and the second end of the capacitor C are connected to the ground terminal of the capacitor C, and the second end of the capacitor C, and the second end of the capacitor C are connected to the capacitor C, and the second end of the capacitor C, and the capacitor C are connected to the ground terminal of the capacitor C, and the second end of the capacitor C are connected to the capacitor C, and.

The first signal output module includes a first signal conversion module, a first amplification module and a first signal output module, wherein the first signal conversion module, the first amplification module and the first signal output module are sequentially connected, the first signal conversion module is used for converting a first frequency signal or a direct current signal into a first square wave signal, the first amplification module is used for amplifying the first square wave signal, the first signal output module is used for correspondingly outputting the amplified first square wave signal to the light source unit, wherein, referring to fig. 8, the first signal conversion module includes a converter FB, a capacitor C resistor R, a sliding resistor R, a first terminal of the converter FB, a first terminal of the capacitor C, a first terminal of the resistor R, a first terminal of the first chip 1 (pin) and a second terminal of the capacitor C (pin o), a resistor C, a second terminal of the capacitor C is connected to a first terminal of the capacitor C, a resistor C, a second terminal of the converter FB, a resistor C, a first terminal of the resistor C, a second terminal of the resistor C, a resistor.

Specifically, referring to fig. 7 again, the second signal generating module includes a resistor R, a transformer 6, a capacitor C, an inductor 22, an inductor 023, and an inductor 124, wherein a pin 36 (pin CH _ IOUT) of the DDS module is connected to a first end of the resistor R and a port 1 of the transformer 26, a pin 35 (pin CH _ IOUT) of the DDS module is connected to a first end of the resistor R and a port 3 of the transformer 36, a second end of the resistor R and a second end of the resistor R are connected to a port 2 and a power terminal of the transformer 46, a port 4 of the transformer 6 is connected to a ground terminal, a port 6 of the transformer 6 is connected to the first end of the capacitor C, the first end of the capacitor C and the first end of the inductor 22, the second end of the capacitor C and the second end of the capacitor C are connected to the ground terminals, and the second end of the capacitor C, the capacitor C and the capacitor C are connected to the ground terminals, and the second end of the capacitor C are connected to the capacitor C, and the second end of the capacitor C terminal of the capacitor C, and the capacitor C are connected to the capacitor C, and the second terminal of the capacitor C, and the capacitor C are connected to the second terminal of the capacitor C, and the capacitor C.

The second signal output module includes a second signal conversion module, a second amplification module and a second signal output module, wherein the second signal conversion module, the second amplification module and the second signal output module are sequentially connected, the second signal conversion module is used for converting a second frequency signal into a second square wave signal, the second amplification module is used for amplifying the second square wave signal, the second signal output module is used for correspondingly outputting the amplified second square wave signal to the light source unit, wherein, please refer to fig. 11, the second signal conversion module includes a converter FB, a capacitor C, a sliding resistor R, a resistor R, and a third chip, the first end of the converter FB is connected with the power supply terminal, the second end of the converter FB is connected with the power supply terminal, the first end of the capacitor C, the first end of the resistor R, the pin 1 (pin VCC) and the pin 8 (pin) of the resistor C, the second end of the capacitor C and the second end of the capacitor C are connected to the power supply terminal, the ground terminal, the resistor C, the ground terminal of the resistor C, the resistor C is connected to the ground terminal of the resistor C, the resistor C is connected to the resistor C, the resistor.

Referring to fig. 14a to 14d, the light source unit of this embodiment includes a gating module, the gating module includes a signal interface module, a plurality of light source communication modules, a light source gating module, and a control module, a resistor R49, and an IPEX joint J29, the light source gating module includes a capacitor C83, a capacitor C84, a resistor R48, and a fifth chip, the control module includes a resistor R50 and a sixth chip, each light source connection module includes a resistor R51, the signal interface module is used to connect a first square wave signal or a second square wave signal, the light source communication module is used to connect a corresponding laser diode, the light source gating module is used to gate which laser diode to light, the control module is used to provide a control signal to the light source communication module, wherein a port 2 and a port 3 of the IPEX joint J29 are connected to a ground terminal, a port 1 of the IPEX joint J29 is connected to the first signal output module and the second, specifically, port 1 of IPEX connector J29 is connected to port 1 of IPEX connector J27 and port 1 of IPEX connector J28, port 1 of IPEX connector J29 is further connected to a first end of resistor R49, a second end of resistor R49 is connected to fifth port V5, seventh port V7 is connected to anodes of all laser diodes, a cathode of each laser diode is connected to a first end of resistor R51, a second end of resistor R51 is connected to an eighth port, all eighth ports are correspondingly connected to pins of a fifth chip, for example, the number of laser diodes is 6, as shown in fig. 14B and 14C, 6 eighth ports are respectively connected to pin 1 (pin B4), pin 2 (pin B3), pin 3 (pin B2), pin 4 (pin B1), pin 14 (pin B6) and pin 15 (pin B5) of the fifth chip, pin 16 (VCC) of the fifth chip is connected to a first end of capacitor C83, a first end of capacitor C84, the second end of the capacitor C83 and the second end of the capacitor C84 are connected to a ground terminal, the pin 5 of the fifth chip is connected to the first end of the resistor R48, the second end of the resistor R48 is connected to the ground terminal, and the control pins of the fifth chip are correspondingly connected to the control pins of the sixth chip, for example, as shown in fig. 14C and 14d, the pin 7 (pin OE), the pin 11 (pin S0), the pin 10 (pin S1), and the pin 9 (pin S2) of the fifth chip are correspondingly connected to the pin 6, the pin 7, the pin 8, and the pin 9 of the sixth chip, the pin 5 of the sixth chip is connected to the first end of the resistor R50, and the second end of the resistor R50 is connected to the seventh port V7.

Referring to fig. 15a-15e, the detection unit of this embodiment further includes a power supply access module, a gain voltage module, a plurality of detector connection modules, a plurality of amplification modules, and a plurality of detection output modules, wherein the power supply access module, the gain voltage module, the detector connection module, the amplification modules, and the detection output modules are sequentially connected, the power supply access module is connected to the power supply module to provide a power supply interface for a circuit related to the detection unit, the gain voltage module is used to provide a gain voltage to the silicon photomultiplier, the detector connection module is used to connect to the corresponding silicon photomultiplier, the amplification module is used to amplify a signal detected by the silicon photomultiplier, the detection output module is connected to the collection module and is used to output a signal detected by the silicon photomultiplier to the collection module, and the power supply access module includes a capacitor C85, a capacitor C86, and a capacitor C, A capacitor C87, a capacitor C88 and a seventh chip, wherein the gain voltage module comprises a capacitor C89, a capacitor C90, a capacitor C91, a capacitor C92, a capacitor C93, a capacitor C94, a resistor R52, a resistor R53, a sliding resistor R54 and an eighth chip, the detector switch-on module comprises a capacitor C95 and a capacitor C96, the amplification module comprises a capacitor C97, a capacitor C98, a capacitor C99, a capacitor C100, a capacitor C101, a resistor 55 and a ninth chip, the detection output module comprises an IPEX connector J1, the first end of the capacitor C85 and the first end of the capacitor C86 are connected with a power supply end, a pin 1 and a pin 2 of the seventh chip, the second end of the capacitor C85 and the second end of the capacitor C86 are connected with a ground end, the first end of the capacitor C87 is connected with a pin 5 and a pin 6 of the seventh chip, the second end of the capacitor C87 is connected with the ground end, the first end of the capacitor C88 is connected with a pin 7 and a pin 8 of the seventh chip, and the second end of the capacitor C88 is connected with the ground end; the first end of the capacitor C89, the first end of the capacitor C90, the first end of the capacitor C91, the first end of the capacitor C85 and the first end of the capacitor C86 are commonly connected with the same power supply terminal, the first end of the capacitor C89, the first end of the capacitor C90 and the first end of the capacitor C91 are further connected with a pin 1 (pin IN), a pin 2 (pin IN), a pin 3 (pin SHDN) and a pin 9 (pin IN) of the eighth chip, the second end of the capacitor C89, the second end of the capacitor C90 and the second end of the capacitor C91 are connected with the ground terminal, the first end of the capacitor C92, the first end of the capacitor C93 and the first end of the capacitor C94 are connected with the power supply terminal, a pin 7 (pin OUT) and a pin 8 (pin OUT) of the eighth chip, the first end of the capacitor C92, the first end of the capacitor C93 and the first end of the capacitor C94 are further connected with the sliding terminal of the sliding resistor R54, the second end of the capacitor C4642, the second end of the, pin 6 (pin ADJ) of the eighth chip is connected to the first end of the resistor R52 and the first end of the resistor R53, the second end of the resistor R52 is connected to the sliding resistor R54, and the second end of the resistor R53 is connected to the ground; pin 1 of each silicon photomultiplier is connected with a first end of a capacitor C95 and a first end of a capacitor C96, the first end of the capacitor C95, the first end of the capacitor C96, the first end of the capacitor C92, the first end of the capacitor C93 and the first end of the capacitor C94 are connected to the same power supply end, the second end of the capacitor C95 and the second end of the capacitor C96 are connected to the ground end, and pin 3 of the silicon photomultiplier is connected with the eighth port V8; each eighth port V8 is correspondingly connected to a pin 4 (pin Vin-), a first end of the resistor 55, and a first end of the capacitor C101, the second end of the resistor 55 and the second end of the capacitor C101 are connected to a pin 1 (pin VOUT) and a ninth port V9 of the ninth chip, the first end of the capacitor C97 and the first end of the capacitor C98 are connected to a pin 5 (pin + Vs) of the ninth chip, the second end of the capacitor C97 and the second end of the capacitor C98 are connected to the ground, the first end of the capacitor C99 and the first end of the capacitor C100 are connected to a pin 2 (pin-Vs) of the ninth chip, the second end of the capacitor C99 and the second end of the capacitor C100 are connected to the ground, each ninth port is correspondingly connected to a port 1 of the IPEX junction J1, a port 2 and a port 3 of the IPEX junction J1 are connected to the ground, and the collection module may be connected to the IPEX junction J1 through the IPEX interface.

Referring to fig. 16, the rotary type diffusion optical imaging system of the present embodiment uses a laser diode as a light source, instead of a conventional light source system of laser, collimator, attenuator and optical fiber; meanwhile, a patch type silicon photomultiplier and a drive circuit based on a flexible PCB are used for replacing a traditional collection system of optical fiber, a photoswitch and PMT, a rotary table is used for driving a laser diode and the silicon photomultiplier to rotate around an imaging cavity so as to obtain a plurality of position data, and multi-channel data collection can be realized through a computer and a multi-channel high-speed collection card. The rotary type diffusion optical imaging system greatly simplifies the complexity of an original system, because the laser diode and the silicon photomultiplier are tightly attached to a measured object, the light loss of the system can be reduced, all channels are synchronously acquired, the acquisition speed of the system is improved, and multi-channel synchronous acquisition is realized. Meanwhile, high-frequency modulation can be added into the laser diode, so that the sampling frequency of the acquisition card used by the rotary diffusion optical imaging system can reach 250M, and the rotary diffusion optical imaging system can be used for frequency domain experiments.

The rotary diffusion optical imaging system of the embodiment further comprises a gain voltage module, each detector has the same gain in the early design stage, namely the detector output for the same light source is consistent, but the following phenomena are found in the measurement: the detector farthest from the light source and the detector nearest to the light source have larger difference in output value, so that the detector nearest to the light source is saturated when the detector farthest from the light source can detect a larger value, and if the detector nearest to the light source is not saturated, the detector farthest from the light source has a small output value, and the detector output is saturated or too low, which will have a larger influence on subsequent data reconstruction, so that the image reconstruction quality is reduced. Based on this practical problem, the present embodiment provides the gain voltage module, because when the SiPM gain is increased, the output signal thereof will also rise, so that a small gain can be set for the detection module with a closer source probe distance and a large gain can be set for the module with a farther source probe distance, so that the SiPM output is in a more ideal interval. In the embodiment, the gain of each detector is independently adjusted, so that the system gain can be dynamically adjusted according to the actual measurement data condition during measurement, and the accuracy of data acquisition is improved. The acquired data is then corrected to the same gain value to optimize the acquired data to improve reconstruction performance.

The embodiment provides a light source modulation method based on square waves, which comprises the following steps: the modulation signal of the current frequency domain system is mainly sine wave, because the sine wave as the modulation signal can be directly calculated without filtering when calculating the phase, the complexity of the system can be reduced compared with other signals. However, tests show that higher modulation depth can be obtained by using the square wave as the modulation signal, and the square wave signal is convenient to generate, but the problem of filtering is faced by using the square wave as the modulation signal. The SiPM is a photoelectric conversion device, and has a lower response frequency compared with the PMT, so that only signals within a specific frequency range can be acquired, that is, the SiPM itself can be used as a low-pass filter. Aiming at the characteristics of the SiPM, the embodiment provides a light source modulation method using a square wave as a modulation signal, when the modulation frequency is higher than half of the cut-off frequency of the SiPM, due to the characteristics of the SiPM, only a fundamental wave signal lower than the cut-off frequency can be acquired, so that other higher harmonic signals can be filtered, so that only a sine signal of a fundamental frequency is reserved in the acquired signal, and a filter circuit is not required to be additionally introduced.

The sampling scheme of the data acquisition unit of this embodiment may be a sampling scheme based on nyquist sampling law, i.e. the sampling frequency needs to be more than 2 times higher than the signal frequency. In addition, the embodiment also provides another low-frequency sampling scheme, and the specific method of the scheme is as follows:

it is known from Nyquist's theorem that if the sampling frequency is less than 2 times the frequency of the sampled signal, the result of the sampling does not truly reflect the sampled signal. However, in the frequency domain mode, the modulation signal frequency is high, for example, in the modulation frequency of 100MHz, the sampling frequency must be greater than 200MHz, which brings difficulty to signal acquisition and increases the system cost, so this embodiment provides a scheme of sampling by using a preset method, where the preset method is to acquire only one electrical signal in one period and acquire one electrical signal every preset period, and when the number of the acquired electrical signals meets the requirement, the sampling may be stopped. In this embodiment, a modulation frequency of 100MHz is taken as an example, as shown in fig. 17, if 8 points are to be acquired in each period, a sampling frequency of at least 800MHz is required, and sampling is performed 8 times in one period, and in order to sample one signal of 100MHz, a sampling frequency of 800MHz is required, and a time interval T between any 2 sampling points is 1/800MHz which is 1.25 ns. However, because of the repeatability of the periodic signal, if the sampling is done only once in a period, with an interval of 80 periods + T between two samplings, the data of fig. 17 can also be obtained by sampling 561 periods, but the sampling frequency needs only 10 MHz. The specific implementation method comprises the following steps: the sampling points in different periods are sequentially superposed to one period, and data in a complete period of the signal can be obtained, as shown in fig. 18a to 18c, the data in fig. 17 can be obtained after sampling for 561 periods, and it is obvious that the result obtained by using the preset method provided by this embodiment is completely the same as the sampling result based on the Nyquist theorem. The preset method provided by the embodiment can greatly reduce the required sampling frequency, thereby reducing the system cost.

The rotation type diffusion optical imaging system of this embodiment uses laser diode and silicon photomultiplier to replace laser instrument and PMT that traditional system was used commonly, very big reduction system complexity, system cost is reduced, simultaneously through using flexible PCB to survey module circuit design, make this system's light source detector can hug closely the testee, therefore light loss in the transmission course has been reduced, the passageway uniformity of SNR and data collection has been improved, the detection module gain design of differentiation has improved the accuracy of surveying data, system performance has been optimized, thereby the reconstruction image quality of system has been improved.

A set of DOT imaging system is designed and established in the embodiment, the system can be used for two-dimensional and three-dimensional steady-state and frequency domain imaging, the optimization and promotion are carried out on the system, and a follow-up system is expected to be used for clinical experiments, so that the benefit is provided for early diagnosis of breast cancer.

In the description of the present invention, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implying any number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless specifically defined otherwise.

In the description herein, references to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above are not necessarily intended to refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, various embodiments or examples described in this specification can be combined and combined by those skilled in the art.

The foregoing is a more detailed description of the invention in connection with specific preferred embodiments and it is not intended that the invention be limited to these specific details. For those skilled in the art to which the invention pertains, several simple deductions or substitutions can be made without departing from the spirit of the invention, and all shall be considered as belonging to the protection scope of the invention.

Claims

1. A rotary diffusion optical imaging system is characterized by comprising a light source unit, a detection unit, a bearing device with an imaging cavity, a rotatable sleeve device and a data acquisition unit, wherein the light source unit comprises a plurality of luminous light sources, the detection unit comprises a plurality of detectors, the sleeve device comprises a sleeve, N rows of through holes M columns are arranged on the sleeve, one luminous light source is correspondingly arranged in each through hole of the mth column, one detector is correspondingly arranged in each through hole except the mth column, the imaging cavity is sleeved with the sleeve,

the data acquisition unit is used for acquiring the electric signal by utilizing a Nyquist sampling law or a preset method, and converting the electric signal into a digital signal, wherein the preset method is to acquire one electric signal every other preset period.

2. The rotary diffusive optical imaging system of claim 1, wherein the light emitting source comprises a laser diode.

3. The rotating diffusive optical imaging system of claim 2, wherein the detector comprises a silicon photomultiplier tube.

4. The rotary diffusive optical imaging system of claim 3, further comprising a modulation signal generating unit connected to the light source unit, the modulation signal generating unit comprising a DDS module, a first signal generating module, a second signal generating module, a first signal output module, a second signal output module, wherein,

the DDS module is used for providing a sine signal;

the first signal output module is connected with the first signal generation module and used for outputting a direct current signal of the first signal generation module, or converting the first frequency signal into a first square wave signal and controlling the modulation depth and the modulation size of the first square wave signal;

5. The rotary diffusion optical imaging system of claim 4, wherein the first signal generating module comprises a resistor R1, a resistor R3, a transformer L1, a capacitor C15, a capacitor C16, a capacitor C17, a capacitor C18, a capacitor C19, a capacitor C20, a capacitor C21, a capacitor C22, a capacitor C23, a capacitor C24, a capacitor C25, an inductor L2, an inductor L20, an inductor L21, wherein,

6. The rotary diffusion optical imaging system of claim 4, wherein the first signal output module comprises a converter FB13, a converter FB15, a converter FB17, a capacitor C66, a capacitor C67, a capacitor C68, a capacitor C74, a capacitor C75, a capacitor C76, a capacitor C77, a capacitor C78, a capacitor C81, a capacitor C82, a resistor R23, a sliding resistor R24, a resistor R25, a resistor R26, a resistor R27, a resistor R28, a resistor R34, a resistor R35, a resistor R36, a resistor R37, a resistor R38, a resistor R43, a resistor R44, a resistor R45, a resistor R46, a resistor 47, a transistor U77, a first chip, a second chip, an IPEX joint J28, wherein,

7. The rotary diffusion optical imaging system of claim 6, wherein the second signal generating module comprises a resistor R4, a resistor R5, a transformer L6, a capacitor C26, a capacitor C27, a capacitor C28, a capacitor C29, a capacitor C30, a capacitor C31, a capacitor C32, a capacitor C33, a capacitor C34, a capacitor C35, a capacitor C36, an inductor L22, an inductor L23, an inductor L24, wherein,

8. The rotary diffusion optical imaging system of claim 7, wherein the second signal output module comprises a converter FB12, a converter FB14, a converter FB16, a capacitor C63, a capacitor C64, a capacitor C65, a capacitor C69, a capacitor C70, a capacitor C71, a capacitor C72, a capacitor C73, a capacitor C79, a capacitor C80, a sliding resistor R17, a resistor R18, a resistor R19, a resistor R20, a resistor R21, a resistor R22, a resistor R29, a resistor R30, a resistor R31, a resistor R32, a resistor R33, a resistor R39, a resistor R40, a resistor R41, a resistor R42, a transistor U5, a third chip, a fourth chip, an IPEX joint J27, wherein,

9. The rotary diffusive optical imaging system of claim 8, wherein the light source unit comprises a gating module comprising a capacitor C83, a capacitor C84, a resistor R48, a resistor R49, a resistor R50, a number of light source connection modules, a fifth chip, a sixth chip, an IPEX junction J29, each of the light source connection modules comprising a resistor R51, wherein,

the ports 2 and 3 of the IPEX connector J29 are connected to a ground terminal, the port 1 of the IPEX connector J29 is connected to the first signal output module and the second signal output module, the port 1 of the IPEX connector J29 is further connected to the first end of the resistor R49, the second end of the resistor R49 is connected to a seventh port, the seventh port is connected to anodes of all the laser diodes, the cathode of each laser diode is connected to the first end of the resistor R51, the second end of the resistor R51 is connected to an eighth port, all the eighth ports are correspondingly connected to pins of the fifth chip, the pin 16 of the fifth chip is connected to the first end of the capacitor C83 and the first end of the capacitor C84, the second end of the capacitor C83 and the second end of the capacitor C84 are connected to a ground terminal, and the pin 5 of the fifth chip is connected to the first end of the resistor R48, the second end of the resistor R48 is connected with a ground terminal, the control pins of the fifth chip are correspondingly connected with the control pins of the sixth chip, the pin 5 of the sixth chip is connected with the first end of the resistor R50, and the second end of the resistor R50 is connected with the seventh port.

10. The rotary diffusion optical imaging system of claim 2, wherein the detection unit comprises a capacitor C85, a capacitor C86, a capacitor C87, a capacitor C88, a capacitor C89, a capacitor C90, a capacitor C91, a capacitor C92, a capacitor C93, a capacitor C94, a plurality of capacitors C95, a plurality of capacitors C96, a resistor R52, a resistor R53, a sliding resistor R54, a seventh chip, an eighth chip, a plurality of amplification modules, a plurality of IPEX joints J1, the amplification modules comprise a capacitor C97, a capacitor C98, a capacitor C99, a capacitor C100, a capacitor C101, a resistor 55 and a ninth chip, wherein,