CN111358844A - Traditional Chinese medicine for clinically treating postoperative complications of anorectal diseases - Google Patents
Traditional Chinese medicine for clinically treating postoperative complications of anorectal diseases Download PDFInfo
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- CN111358844A CN111358844A CN202010325927.8A CN202010325927A CN111358844A CN 111358844 A CN111358844 A CN 111358844A CN 202010325927 A CN202010325927 A CN 202010325927A CN 111358844 A CN111358844 A CN 111358844A
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Abstract
The invention discloses a traditional Chinese medicine for clinically treating postoperative complications of anorectal diseases, which comprises the following raw materials in parts by weight: 15-25 parts of coptis chinensis, 20-30 parts of gallnut, 15-25 parts of purslane, 5-10 parts of mirabilite, 8-12 parts of corydalis tuber, 10-15 parts of folium artemisiae argyi, 6-10 parts of red paeony root and 10-15 parts of cortex acanthopanacis. The traditional Chinese medicine for treating postoperative complications of anorectal diseases is obtained by screening traditional Chinese medicine components and scientifically and reasonably proportioning according to the theory of traditional Chinese medicine, can obviously improve local blood circulation of anus when prepared into fumigation lotion for clinical treatment of postoperative complications of anorectal diseases, obviously reduces disappearance time of postoperative pain, edema and other complications, promotes wound healing, has obvious clinical curative effect, no toxic or side effect, is safe and effective, is particularly suitable for postoperative pain, edema and healing of anorectal diseases, and is worthy of clinical popularization.
Description
Technical Field
The invention relates to the technical field of anorectal disease treatment, in particular to a traditional Chinese medicine for clinically treating postoperative complications of anorectal diseases.
Background
As a method for treating anorectal diseases, surgery plays an important role. However, the surgery causes various injuries, i.e., complications, to the patients according to the difference in constitutions of each patient. The common postoperative complications of anorectal diseases, such as pain, bleeding, constipation, unhealed wounds, infection and the like, are common clinical diseases, and not only are serious pains caused to patients in anorectal operations, but also the operation curative effect and postoperative life quality of the patients are seriously affected. Therefore, the method for discussing the prevention and treatment of postoperative complications of anorectal diseases has important clinical significance.
Although western medicines can relieve a part of postoperative discomfort symptoms of anorectal diseases, the side effects are large. Traditional Chinese medicine considers that damp-heat is the main cause of anorectal diseases. The perianal channels and collaterals are directly injured by surgical trauma of anorectal diseases, so that local channels and collaterals are blocked, and qi and blood stasis are caused; in addition, although local lesions are removed in the operation treatment, damp-heat pathogenic qi still exists in the body of a patient, so that the anorectal disease after the operation is frequently accompanied by the pathogenic qi of 'damp, heat and stasis', and the pathogenesis of the anorectal disease postoperative complications mainly comprises meridian damage, tendon relaxation, blood stasis blocking collaterals, downward flow of damp-heat, qi stagnation and blood stasis, unsmooth qi and blood circulation and pain caused by stagnation.
Disclosure of Invention
The invention aims to solve the defects in the prior art and provides a traditional Chinese medicine for clinically treating postoperative complications of anorectal diseases.
A traditional Chinese medicine for treating postoperative complications of anorectal diseases comprises the following raw materials in parts by weight: 15-25 parts of coptis chinensis, 20-30 parts of gallnut, 15-25 parts of purslane, 5-10 parts of mirabilite, 8-12 parts of corydalis tuber, 10-15 parts of folium artemisiae argyi, 6-10 parts of red paeony root and 10-15 parts of cortex acanthopanacis.
Preferably, the traditional Chinese medicine is prepared from the following raw materials in parts by weight: 20 parts of coptis chinensis, 30 parts of gallnut, 15 parts of purslane, 8 parts of mirabilite, 10 parts of corydalis tuber, 15 parts of folium artemisiae argyi, 6 parts of red paeony root and 12 parts of cortex acanthopanacis.
Preferably, the traditional Chinese medicine is used for carrying out traditional Chinese medicine clinical treatment on postoperative complications of the anorectal diseases in the form of fumigation and washing liquid.
Preferably, the preparation method of the fumigation solution comprises the following steps:
s1, weighing rhizoma Coptidis, Galla chinensis, herba Portulacae, Natrii sulfas, rhizoma corydalis, folium Artemisiae Argyi, radix Paeoniae Rubra, and cortex Acanthopancis, and pulverizing to obtain fine powder;
s2, adding the fine powder obtained in the step S1 into water which is 10-15 times of the weight of the traditional Chinese medicinal materials, decocting for the first time, filtering, and collecting filtrate and dregs of a decoction;
s3, adding water with the weight being 8-10 times that of the traditional Chinese medicine into the medicine dregs obtained in the step S2, decocting for the second time, filtering, and collecting filtrate;
s4, combining the filtrates obtained in the steps S2 and S3, concentrating to obtain a concentrated solution, and then adding water to dilute to 1.5-2L to obtain the lotion.
Preferably, in step S1, the particle size of the fine powder is 200-280 μm.
Preferably, in step S4, the two filtrates are combined, concentrated and concentrated to a volume of solution: the weight of the traditional Chinese medicinal materials is = 1: 1.0-1.5, adding water, and diluting to 1.8-2L to obtain lotion.
Preferably, before fumigating anus and perianal, fumigating lotion is heated to 39-42 deg.C for use.
Compared with the prior art, the invention has the following beneficial effects:
the traditional Chinese medicine for treating postoperative complications of anorectal diseases is obtained by screening traditional Chinese medicine components and scientifically and reasonably proportioning according to the theory of traditional Chinese medicine, can obviously improve local blood circulation of anus when prepared into fumigation lotion for clinical treatment of postoperative complications of anorectal diseases, obviously reduces disappearance time of postoperative pain, edema and other complications, promotes wound healing, has obvious clinical curative effect, no toxic or side effect, is safe and effective, is particularly suitable for postoperative pain, edema and healing of anorectal diseases, and is worthy of clinical popularization.
According to the records of the traditional Chinese medicine history, the pharmacological activity of the medicinal materials is as follows:
coptis chinensis: damp-heat fullness and distention, vomiting and acid regurgitation are indicated for gastric and abdominal fullness, nausea and vomiting due to damp-heat blocking the middle energizer, stomach heat vomiting, hypochondriac pain due to liver-fire invading the stomach, vomiting and acid regurgitation due to deficiency-cold of spleen and stomach, vomiting of sour water. Carbuncle, swelling, furuncle, sore, conjunctival congestion and toothache: it is indicated for abscess, deep-rooted boil, red eyes with swelling and pain, pterygium of red pulse, upward attack of stomach fire, and toothache. It can be used for treating eczema, and purulent auditory meatus.
Gallnut: astringe lung to reduce fire, astringe intestine to check diarrhea, astringe sweat, stop bleeding, astringe dampness to heal wound. Can be used for treating chronic cough due to lung deficiency, chronic diarrhea, spontaneous perspiration, night sweat, diabetes, hemafecia, hemorrhoidal bleeding, traumatic hemorrhage, carbuncle, sore, and skin ulcer.
Purslane: clearing away heat and toxic material, inducing diuresis and removing dampness, dissipating blood and detumescence, removing dust and sterilizing, diminishing inflammation and relieving pain, and stopping bleeding and cooling blood. Can be used for treating dysentery, enteritis, nephritis, puerperal metrorrhagia, hematochezia, mastitis, etc. Selecting tender stem and leaf of Portulaca oleracea L of Portulacaceae.
Mirabilite: purging heat and relaxing bowels, moistening dryness and softening hard mass, and is mainly used for clearing fire and relieving swelling. Used for treating excessive heat constipation, abdominal pain due to stagnation, and intestinal abscess with swelling and pain; it is indicated for acute mastitis, hemorrhoid with swelling and pain. Indications are as follows: 1. can be used for treating constipation and intestinal abnormal fermentation; 2. used for obstructive jaundice and chronic cholecystitis; 3. can be used for treating eclampsia, uremia, tetanus, hypertensive encephalopathy, and acute renal hypertensive crisis; 4. it is applied by hot compress for external use to relieve inflammation and swelling.
Rhizoma corydalis: irregular menstruation, abdominal mass, metrorrhagia and stranguria, puerperal blood diseases, blood circulation, sudden blood rushing upwards, and blood loss, and can be used for promoting qi circulation, relieving pain, promoting blood circulation, removing blood stasis, and treating traumatic injury.
Folium artemisiae argyi: regulating menstruation, stopping bleeding, preventing miscarriage, relieving metrorrhagia, dispelling cold, and removing dampness. Can be used for treating menoxenia, dysmenorrhea, abdominal pain, abortion, metrorrhagia, asthma, cough, and phlegm; hemostasis and anticoagulation effects; sedative and antiallergic effects; protecting liver and promoting function of gallbladder, and can be used for treating rheumatic arthritis, headache, and endogenous wind. Folium Artemisiae Argyi also has antibacterial and antiviral effects.
Red peony root: nourishing yin, removing blood stasis, relieving pain, cooling blood, and relieving swelling. It can be used for treating amenorrhea due to blood stasis, hernia, abdominal mass, abdominal pain, hypochondriac pain, epistaxis, dysentery with bloody stool, hematochezia, conjunctival congestion, carbuncle, swelling, and traumatic injury.
Cortex acanthopanacis: dispel wind-damp, tonify liver and kidney, strengthen tendons and bones, activate blood. In clinic, it can be used for treating rheumatic arthritis, such as lumbago, gonalgia, tendons and bones contracture, traumatic injury, fracture, edema, tinea pedis, damp scrotum, and asthenia.
Chinese medicine fumigation and washing therapy is an old and effective therapy. As early as in the book of the "internal classic", there is a record that the sweat is accumulated in the body of the patient with the pathogenic factors. Modern medicine considers that the fumigation-washing method is to make the effective components of the liquid medicine penetrate the skin or the granulation tissue of the wound surface to absorb so as to play the pharmacology of anti-inflammation, detumescence and the like by means of the temperature of the liquid medicine.
Detailed Description
The technical solution of the present invention will be further explained with reference to the following specific embodiments.
Example 1
Crude drug prescription: 20g of coptis chinensis, 30g of gallnut, 15g of purslane, 8g of mirabilite, 10g of corydalis tuber, 15g of folium artemisiae argyi, 6g of red paeony root and 12g of cortex acanthopanacis.
The preparation method of the fumigation lotion prepared from the traditional Chinese medicines comprises the following steps: weighing the traditional Chinese medicine raw materials, cleaning, removing impurities, drying, crushing, adding water with the weight of 10 times of the traditional Chinese medicine, decocting for 2 hours, filtering, and collecting filtrate; adding water with the weight 10 times of that of the traditional Chinese medicinal materials into the dregs of a decoction, decocting for 0.5h, filtering, collecting filtrate, combining the two filtrates, and concentrating to obtain a solution volume: the weight of the traditional Chinese medicinal materials is = 1: 1.2, adding water to dilute the liquid medicine to 2L, and subpackaging 500mL per bag.
And (3) clinical trials:
100 patients with anorectal diseases are selected for operation, local anesthesia is received before the operation, and operation area pain appears within 2-24 h after the operation. The test group and the control group are randomly divided into 50 cases. The two groups were comparable without difference in sex, age, disease type, and pain level.
Test groups: the patient adopts an ultrasonic atomization fumigation-washing instrument for traditional Chinese medicine fumigation-washing, and the operation method is implemented according to the traditional Chinese medicine nursing conventional technical operating instructions. An ultrasonic atomization fumigation-washing instrument is selected as an instrument, the traditional Chinese medicine fumigation-washing liquid prepared according to the example 1 is added, and the temperature of the liquid medicine is heated to 39-42 ℃ before anus and perianal area are fumigated. Carrying out fog therapy for 5min, then fumigating and washing for 8min, and carrying out anus lifting exercise while fumigating and washing.
Control group: patients adopt a potassium permanganate solution with the ratio of 1:5000 as a fumigation solution for fumigation. Temperature control and operating procedures were consistent with the experimental groups.
The two groups of patients use the composition after defecation after 2 days of operation, 1 time per day, 10-15 min each time, and 5 days are 1 course of treatment. After one treatment course, the comprehensive curative effect and the symptom improvement condition of the continuous test are judged and compared.
1. The criteria for therapeutic effect are as follows: the effect is shown: the pain of the anus is obviously relieved, the defecation is free from obstruction, the wound is free from bleeding and exudation, and the wound healing time is obviously shortened; the method has the following advantages: the pain of the anus is relieved, the pain of defecation is relieved, bleeding and exudation of the wound are avoided, and the healing time of the wound is shortened; and (4) invalidation: pain in the anus, pain in defecation, and dyschezia.
2. Clinical curative effect
2.1 therapeutic results
TABLE 1 comparison of the efficacy of the two groups of patients
| Group of | Number of cases | Recovery method | Show effect | Is effective | Invalidation | Display efficiency | Total effective rate |
| Control group | 50 | 0 | 18 | 21 | 11 | 36% | 78.2% |
| Test group | 50 | 4 | 30 | 16 | 0 | 68% | 100% |
As can be seen from the results in Table 1, the clinical significant efficiencies of the test group and the control group are respectively (68.0% vs 36.0%), and the curative effect test group is obviously higher than the control group; the clinical total effective rate of the test group and the control group is respectively (100% vs 78.2%), and the curative effect test group is obviously higher than the control group.
2.2 postoperative complications (pain, edema, etc.) and wound healing time
TABLE 2 comparison of clinical symptoms (days) in two groups after treatment
Note: p <0.05, P < 0.01 compared to control.
As can be seen from the results in Table 2, the time required for the postoperative pain, edema and other complications to disappear in the test group is significantly shorter than that in the control group, and P is less than 0.05; the wound healing time was significantly shorter than in the control group, P < 0.05.
The traditional Chinese medicine fumigation and washing liquid prepared by the embodiment can obviously improve local blood circulation of anus, obviously reduce postoperative pain, edema and other complications, promote wound healing, has obvious clinical curative effect, and is worthy of clinical popularization and application.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.
Claims (7)
1. The traditional Chinese medicine for clinically treating postoperative complications of anorectal diseases is characterized by comprising the following raw materials in parts by weight: 15-25 parts of coptis chinensis, 20-30 parts of gallnut, 15-25 parts of purslane, 5-10 parts of mirabilite, 8-12 parts of corydalis tuber, 10-15 parts of folium artemisiae argyi, 6-10 parts of red paeony root and 10-15 parts of cortex acanthopanacis.
2. The traditional Chinese medicine for clinically treating postoperative complications of anorectal diseases according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 20 parts of coptis chinensis, 30 parts of gallnut, 15 parts of purslane, 8 parts of mirabilite, 10 parts of corydalis tuber, 15 parts of folium artemisiae argyi, 6 parts of red paeony root and 12 parts of cortex acanthopanacis.
3. The traditional Chinese medicine for clinically treating the postoperative complications of the anorectal diseases according to claim 1 or 2, which is in the form of a fumigation solution.
4. The traditional Chinese medicine for clinically treating postoperative complications of anorectal diseases in traditional Chinese medicine according to claim 3, wherein the preparation method of the fumigation solution comprises the following steps:
s1, weighing rhizoma Coptidis, Galla chinensis, herba Portulacae, Natrii sulfas, rhizoma corydalis, folium Artemisiae Argyi, radix Paeoniae Rubra, and cortex Acanthopancis, and pulverizing to obtain fine powder;
s2, adding the fine powder obtained in the step S1 into water which is 10-15 times of the weight of the traditional Chinese medicinal materials, decocting for the first time, filtering, and collecting filtrate and dregs of a decoction;
s3, adding water with the weight being 8-10 times that of the traditional Chinese medicine into the medicine dregs obtained in the step S2, decocting for the second time, filtering, and collecting filtrate;
s4, combining the filtrates obtained in the steps S2 and S3, concentrating to obtain a concentrated solution, and then adding water to dilute to 1.5-2L to obtain the lotion.
5. The traditional Chinese medicine for clinically treating postoperative complications of anorectal diseases according to claim 4, wherein in step S1, the particle size of the fine powder is 200-280 μm.
6. The traditional Chinese medicine for clinically treating postoperative complications of anorectal diseases according to claim 4, wherein in step S4, the two filtrates are combined, concentrated and concentrated to a solution volume: the weight of the traditional Chinese medicinal materials is = 1: 1.0-1.5, adding water, and diluting to 1.8-2L to obtain lotion.
7. The traditional Chinese medicine for clinically treating postoperative complications of anorectal diseases according to claim 3, wherein the fumigation solution is heated to 39-42 ℃ before fumigation and washing of anus and perianal region.
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