CN111346145A - Traditional Chinese medicine composition, preparation method thereof, external medicine and application - Google Patents
Traditional Chinese medicine composition, preparation method thereof, external medicine and application Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/285—Aucklandia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/754—Evodia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Abstract
The invention relates to the field of medicines, and particularly discloses a traditional Chinese medicine composition, a preparation method thereof, an external medicine and an application thereof, wherein the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 10-80 parts of clove, 10-100 parts of cinnamon, 10-100 parts of fructus evodiae, 10-100 parts of elecampane, 10-100 parts of gallnut and a proper amount of ginger juice. The traditional Chinese medicine composition prepared by the embodiment of the invention can be used for treating colitis through reasonable compatibility of Chinese herbal medicines such as clove, cinnamon, fructus evodiae, radix aucklandiae, gallnut and the like, has simple preparation method, is easy to implement, can accelerate the repair of intestinal mucosa damaged by inflammation, has high safety, no toxic or side effect and convenient use due to the adoption of the Chinese herbal medicine raw materials, avoids the wound caused by operation treatment, and solves the problems of great toxic and side effects and great wound of the existing method for treating colitis.
Description
Technical Field
The invention relates to the field of medicines, in particular to a traditional Chinese medicine composition, a preparation method thereof, an external medicine and application.
Background
Colitis is an inflammatory disease in which the mucous membrane of colon is invaded and destroyed by inflammatory cells, causing congestion, hemorrhage, edema and ulcer of the mucous membrane of intestine, the pathological changes mainly affect the mucous membrane of colon and submucosa of colon, and the pathological changes can be diffused to the whole colon in severe cases.
At present, the western medicine clinical treatment mode for colitis comprises two treatment modes, namely western medicine and operation. The medicines mainly comprise a salicylic acid inhibitor, corticosteroid, an immunosuppressant and the like, although the treatment methods are quite many, the medicines have certain toxic and side effects, the operative treatment has high traumatic property and easy relapse, and patients need to be specially nursed after the operation.
Moreover, the above technical solution has the following disadvantages in practical use: the existing method for treating colitis has the problems of great toxic and side effects and great wound, and brings great pain to patients.
Disclosure of Invention
The embodiment of the invention aims to provide a traditional Chinese medicine composition, a preparation method thereof, an external medicine and application thereof, and aims to solve the problems of great toxic and side effects and great wound of the existing method for treating colitis in the background art.
In order to achieve the purpose, the invention provides the following technical scheme:
a traditional Chinese medicine composition comprises the following raw materials in parts by weight: 10-80 parts of clove, 10-100 parts of cinnamon, 10-100 parts of fructus evodiae, 10-100 parts of elecampane, 10-100 parts of gallnut and a proper amount of ginger juice.
The clove, the cinnamon, the fructus evodiae, the elecampane and the gallnut are all traditional Chinese medicine names, for example, the fructus evodiae is dry nearly mature fruit of rutaecarpa, the rock tiger or the hairy fructus evodiae of Rutaceae, has the effects of dispelling cold and relieving pain, calming adverse-rising energy and preventing vomiting, and supporting yang and relieving diarrhea, and is used for treating jueyin headache, cold hernia and abdominal pain, cold dampness and beriberi, abdominal pain during menstruation, abdominal distension and pain, vomiting and acid regurgitation, morning diarrhea and the like; the radix aucklandiae is dried root of Compositae plant radix aucklandiae, has effects of activating qi-flowing, relieving pain, invigorating spleen and resolving food stagnation, and can be used for treating symptoms of chest and hypochondrium, abdominal distention and pain, diarrhea and dysentery with tenesmus, dyspepsia, anorexia, etc.
As a further scheme of the invention: the ginger juice is prepared by removing mud from rhizoma Zingiberis recens, cleaning, soaking in clear water for about 30 min, peeling, cutting, squeezing or mashing to obtain juice, and filtering to remove impurities.
As a still further scheme of the invention: the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 30-60 parts of clove, 30-80 parts of cinnamon, 30-80 parts of fructus evodiae, 30-80 parts of elecampane, 30-80 parts of Chinese gall and a proper amount of ginger juice.
Preferably, the dosage of the ginger juice is 0.01-1 time of the total weight of the clove, the cinnamon, the evodia rutaecarpa, the costustoot and the gallnut.
Another object of the embodiments of the present invention is to provide a method for preparing a Chinese medicinal composition, which comprises the following steps:
1) weighing clove, cinnamon, fructus evodiae, elecampane and gallnut according to the weight parts, drying and then crushing to obtain powder;
2) adding ginger juice into the powder obtained in the step 1) and mixing to obtain the traditional Chinese medicine composition.
The clove has the effects of warming the middle-jiao, warming the kidney and lowering the adverse flow of qi; the cinnamon has the main effects of warming and invigorating kidney yang, guiding fire to origin, dispelling cold and relieving pain, warming channels and activating blood; the fructus evodiae has the effects of warming the middle-jiao, relieving pain, regulating qi and eliminating dampness; the radix aucklandiae has the effects of promoting qi circulation, relieving pain, invigorating spleen, regulating stomach function, and promoting digestion; the Galla chinensis has effects of activating qi-flowing, relieving pain, invigorating spleen, regulating stomach function, and resolving food stagnation.
As a still further scheme of the invention: the dosage of the ginger juice is 0.01-1 time of the total weight of the clove, the cinnamon, the evodia rutaecarpa, the costus root and the gallnut.
As a still further scheme of the invention: the grinding condition is that the powder is ground to 10-800 meshes and sieved to obtain powder.
Another object of the embodiments of the present invention is to provide a Chinese medicinal composition prepared by the above preparation method.
Another object of the embodiments of the present invention is to provide an application of the Chinese medicinal composition in preparing a medicament for treating constipation colitis and/or diarrhea colitis.
Another objective of the embodiments of the present invention is to provide an external use medicine, which partially or completely contains the above-mentioned Chinese medicinal composition.
As a still further scheme of the invention: the dosage form of the externally applied medicine is patch, paste or powder.
Preferably, the external preparation may be in the form of a patch.
As a still further scheme of the invention: the preparation method of the externally applied agent in the form of a patch comprises the following steps: the traditional Chinese medicine composition is placed in the acupoint application to obtain the patch, the addition amount of the traditional Chinese medicine composition is not limited, and the traditional Chinese medicine composition can be added according to the addition amount in the prior art, and is generally placed in a central groove of the acupoint application to fill the groove.
As a still further scheme of the invention: the acupuncture point is applied ointment or plaster to be current product, for example can be the acupuncture point that sunshine sea xu medical instrument limited company produced is applied ointment or plaster, be applicable to because of cervical spondylopathy, scapulohumeral periarthritis, hyperostosis, lumbar disc herniation, rheumatoid arthritis, the low back and leg pain, traumatic injury etc. arouse, and can play the effect of refreshment, alleviate fatigue, also can be other applications, for example, the application of producing of Jinan kang people pharmaceutical technology limited company, adopt the material of non-woven fabrics, paint the traditional chinese medicine cream body on the non-woven fabrics, can also be the non-woven fabrics, the center is equipped with the recess that is used for placing the medicine, all can adopt prior art to realize, specifically select according to the demand, here does not do not limit.
As a still further scheme of the invention: the traditional Chinese medicine composition is best prepared at present, if the conditions are limited, clove, cinnamon, evodia rutaecarpa, elecampane and gallnut can be weighed, dried and crushed to obtain powder, then subpackaged and stored, when in need, ginger juice is added to mix into paste to obtain the traditional Chinese medicine composition, and the traditional Chinese medicine composition is placed in an acupoint application to obtain a patch for application.
As a still further scheme of the invention: the use method of the externally applied agent in the form of a patch comprises the following steps: the external medicine is pasted on specific acupuncture points which at least comprise Tianshu acupuncture point, Shanghai deficiency acupuncture point, Shenque acupuncture point and Sanyinjiao acupuncture point, and the acupuncture points are used together to lead the damp in the intestines to be self-dissolved and regulate the large intestine qi.
Another object of the embodiments of the present invention is to provide an application of the above-mentioned Chinese medicinal composition in preparing a medicament for treating colitis and/or proctitis.
Compared with the prior art, the invention has the beneficial effects that:
the traditional Chinese medicine composition prepared by the embodiment of the invention can be used for treating colitis by reasonably matching the Chinese herbal medicines such as clove, cinnamon, evodia rutaecarpa, costus root, gallnut and the like, has the advantages of no toxic or side effect, no stimulation and easy obtainment of raw materials, can accelerate the repair of intestinal mucosa damaged by inflammation, improves the immunity of organisms, and fundamentally cures colitis.
Detailed Description
The present invention will be described in further detail with reference to specific examples. The following examples will assist those skilled in the art in further understanding the invention, but are not intended to limit the invention in any way. It should be noted that variations and modifications can be made by persons skilled in the art without departing from the spirit of the invention. All falling within the scope of the present invention.
The present invention will be described in detail with reference to the following embodiments.
The invention relates to an external traditional Chinese medicine composition for treating colitis, which comprises the following components in percentage by weight: 10-80 parts of clove, 10-100 parts of cinnamon, 10-100 parts of fructus evodiae, 10-100 parts of elecampane, 10-100 parts of gallnut and a proper amount of ginger juice.
The functions of the components in the traditional Chinese medicine composition are as follows: flos Caryophylli and radix aucklandiae are used for regulating qi and relieving pain, flos Caryophylli is mainly used for warming kidney and tonifying yang, and radix aucklandiae is mainly used for removing food stagnation and resolving food stagnation; cinnamon and fructus evodiae are used as ministerial drugs, and the drugs have the effects of warming kidney, tonifying yang, warming channels and relieving pain; the gallnut is used as an adjuvant to guide, namely astringe and stop diarrhea, protect the wound surface, and prevent the clove and the costustoot from moving qi and removing stagnation too much, so that the gallnut can be used for regulating qi movement of spleen, stomach and intestines to a certain degree; the ginger juice warms yang and dispels cold, stimulates the skin, and harmonizes the other drugs so that the drugs can reach the viscera internally. The medicines are used together to warm the spleen and tonify the kidney, dry dampness and check diarrhea, and promote ulcer healing.
The functional indications are as follows: can be used for treating colitis, and has effects in warming kidney, tonifying yang, astringing, promoting diuresis, activating qi-flowing, and relieving diarrhea.
The usage and dosage are as follows: the external medicine is pasted on specific acupuncture points which at least comprise Tianshu acupuncture point, Shanghai deficiency acupuncture point, Shenque acupuncture point and Sanyinjiao acupuncture point, and the acupuncture points are used together to lead the damp in the intestines to be self-dissolved and regulate the large intestine qi.
Example 1
A traditional Chinese medicine composition comprises the following raw materials: 10g of clove, 10g of cinnamon, 10g of fructus evodiae, 10g of costus root, 10g of gallnut and a proper amount of ginger juice.
In this embodiment, the preparation method of the Chinese medicinal composition is as follows:
1) weighing 10g of clove, 10g of cinnamon, 10g of fructus evodiae, 10g of costustoot and 10g of gallnut, drying and then crushing to obtain powder; wherein the granularity of the powder is 10 meshes;
2) adding ginger juice into the powder obtained in the step 1) and mixing to obtain the traditional Chinese medicine composition; wherein the dosage of the ginger juice is 0.01 times of the total weight of the clove, the cinnamon, the evodia rutaecarpa, the costustoot and the gallnut.
In the embodiment, the prepared traditional Chinese medicine composition is placed in an acupoint application according to the amount of 5 g/patch to obtain a patch, and when the patch is used, the external medicine is pasted on specific acupoints, wherein the specific acupoints at least comprise Tianshu acupoint, Shanghao-deficiency acupoint, Shenque acupoint and Sanyinjiao acupoint, and the combination of the acupoints can enable dampness in intestines to be self-dissolved and regulate qi in large intestines, so that the patch can be used for treating colitis.
Example 2
A traditional Chinese medicine composition comprises the following raw materials: 80g of clove, 100g of cinnamon, 100g of fructus evodiae, 100g of costus root, 100g of gallnut and a proper amount of ginger juice.
In this embodiment, the preparation method of the Chinese medicinal composition is as follows:
1) weighing 80g of clove, 100g of cinnamon, 100g of fructus evodiae, 100g of costustoot and 100g of gallnut, drying and then crushing to obtain powder; wherein the granularity of the powder is 800 meshes;
2) adding ginger juice into the powder obtained in the step 1) and mixing to obtain the traditional Chinese medicine composition; wherein the dosage of the ginger juice is 1 time of the total weight of the clove, the cinnamon, the evodia rutaecarpa, the costustoot and the gallnut.
In this embodiment, the prepared Chinese medicinal composition is prepared into paste according to the existing method, and can be used for treating constipation colitis and diarrhea colitis.
Example 3
A traditional Chinese medicine composition comprises the following raw materials: 30g of clove, 30g of cinnamon, 30g of fructus evodiae, 30g of costus root, 30g of gallnut and a proper amount of ginger juice.
In this embodiment, the preparation method of the Chinese medicinal composition is as follows:
1) weighing 30g of clove, 30g of cinnamon, 30g of fructus evodiae, 30g of costustoot and 30g of gallnut, drying and then crushing to obtain powder; wherein the granularity of the powder is 400 meshes;
2) adding ginger juice into the powder obtained in the step 1) and mixing to obtain the traditional Chinese medicine composition; wherein the dosage of the ginger juice is 0.1 time of the total weight of the clove, the cinnamon, the evodia rutaecarpa, the costustoot and the gallnut.
In the embodiment, the prepared traditional Chinese medicine composition is prepared into powder according to the existing method, and can be used for treating colitis and proctitis.
Example 4
A traditional Chinese medicine composition comprises the following raw materials: 60g of clove, 80g of cinnamon, 80g of fructus evodiae, 80g of costus root, 80g of Chinese gall and a proper amount of ginger juice.
In this embodiment, the preparation method of the Chinese medicinal composition is as follows:
1) weighing 60g of clove, 80g of cinnamon, 80g of fructus evodiae, 80g of costustoot and 80g of gallnut, drying and then crushing to obtain powder; wherein the granularity of the powder is 400 meshes;
2) adding ginger juice into the powder obtained in the step 1) and mixing to obtain the traditional Chinese medicine composition; wherein the dosage of the ginger juice is 0.1 time of the total weight of the clove, the cinnamon, the evodia rutaecarpa, the costustoot and the gallnut.
In the embodiment, the prepared traditional Chinese medicine composition is placed in an acupoint application according to the amount of 2 g/patch to obtain a patch, and when the patch is used, the external medicine is pasted on specific acupoints, wherein the specific acupoints at least comprise Tianshu acupoint, Shanghao-deficiency acupoint, Shenque acupoint and Sanyinjiao acupoint, and the combination of the acupoints can enable dampness in intestines to be self-dissolved and regulate qi in large intestines, so that the patch can be used for treating colitis.
Example 5
A traditional Chinese medicine composition comprises the following raw materials: 45g of clove, 55g of cinnamon, 55g of fructus evodiae, 55g of costus root, 55g of Chinese gall and a proper amount of ginger juice.
In this embodiment, the preparation method of the Chinese medicinal composition is as follows:
1) weighing 45g of clove, 55g of cinnamon, 55g of fructus evodiae, 55g of costustoot and 55g of gallnut, drying and then crushing to obtain powder; wherein the granularity of the powder is 400 meshes;
2) adding ginger juice into the powder obtained in the step 1) and mixing to obtain the traditional Chinese medicine composition; wherein the dosage of the ginger juice is 0.1 time of the total weight of the clove, the cinnamon, the evodia rutaecarpa, the costustoot and the gallnut.
In the embodiment, the prepared traditional Chinese medicine composition is placed in an acupoint application according to the amount of 2 g/patch to obtain a patch, and when the patch is used, the external medicine is pasted on specific acupoints, wherein the specific acupoints at least comprise Tianshu acupoint, Shanghao-deficiency acupoint, Shenque acupoint and Sanyinjiao acupoint, and the combination of the acupoints can enable dampness in intestines to be self-dissolved and regulate qi in large intestines, so that the patch can be used for treating colitis.
Example 6
700 out-patient patients with colitis, 15-69 years old, had symptoms of congestion of intestinal mucosa, hemorrhage, edema, ulcer, etc. The 700 outpatients of colitis were divided into the treatment group and the control group by a random method, wherein 652 patients were treated in the treatment group, 48 patients were treated in the control group, and the data of age, disease condition and the like of the two groups were not obviously different and were comparable.
The outpatient of colitis in a treatment group is treated by a conventional treatment method (1 time per day and 4 weeks of treatment course) and the traditional Chinese medicine composition prepared in the embodiment 5 of the invention is used for administration, specifically, the prepared traditional Chinese medicine composition is placed in an acupoint application according to the amount of 2 g/application to obtain a patch, and the external medicine is applied to a specific acupoint when in use, wherein the specific acupoint at least comprises Tianshu acupoint, Shangjuxue acupoint, Shenque acupoint and Sanyinjiao acupoint for 1 time per day and 4 weeks of treatment course. The control group was treated with conventional treatment alone (1.0 g of sulfasalazine per person 1 time daily for 4 weeks of treatment).
After the treatment period, patients in the treatment group and the control group were subjected to colonoscopy (specifically, observation of changes in congestion and edema of the intestinal mucosa and ulcer) and recorded for the degree of reduction of clinical symptoms (abdominal pain, diarrhea, abdominal distension, tenesmus, and bowel sounds), and the results were counted, wherein the degree of reduction was represented by "+" and the greater the number, the greater the degree of reduction, and the specific treatment results are shown in table 1.
TABLE 1 therapeutic results Table
As can be seen from the data in Table 1, the traditional Chinese medicine composition prepared by the embodiment of the invention can be matched with oral medicines to accelerate the repair of intestinal mucosa damaged by inflammation, improve the immunity of the organism, fundamentally cure colitis and eliminate the trouble of diseases to patients; moreover, the traditional Chinese medicine has the characteristics of obviously shortening the course of disease and having high cure rate. The traditional Chinese medicine composition adopts Chinese herbal medicine raw materials, has high safety, no toxic or side effect and convenient use, avoids wound caused by operation treatment, and can remarkably relieve the pain of a patient. The medicine effects of the medicinal materials are combined with the stimulation effect of meridian points to take effect, the medicine points are used together and supplement each other, the medicine has the advantages of no wound and no toxic or side effect, can invigorate spleen, dispel cold, clear dampness and heat, warm yang and tonify kidney, and has the advantages of easily available raw materials, simple preparation, low cost and high safety.
The traditional Chinese medicine composition prepared by the embodiment of the invention can be used for tonifying spleen and removing dampness through conditioning the traditional Chinese medicine, and can be used for treating the intestinal dampness by combining all points, so that the intestinal dampness can be automatically changed, the large intestine qi can be regulated together, and the diarrhea can be stopped automatically.
Explained from the perspective of western medicine, the transdermal absorption of the patch prepared by using the Chinese medicinal composition after use can be summarized into 3 steps: step 1, the effective components of the medicine are released and attached to the skin; step 2, the effective components penetrate the epidermis to enter subcutaneous tissues, and the patch is closely attached to the skin, so that the skin temperature is increased, pores can be expanded, and the effective components can penetrate the skin; and step 3, the medicine continuously permeates into capillary vessels to be dissolved in blood circulation to take effect, and the acupoint application mode avoids the first-pass effect and adverse reaction caused by the medicine passing through the digestive tract.
The traditional Chinese medicine composition has the beneficial effects that the traditional Chinese medicine composition prepared by the embodiment of the invention can be used for treating colitis by reasonably matching the Chinese herbal medicines such as clove, cinnamon, fructus evodiae, elecampane, gallnut and the like, has the advantages of no toxic or side effect, no stimulation and easily obtained raw materials, can accelerate the repair of intestinal mucosa damaged by inflammation, improves the immunity of organisms, fundamentally cures colitis, and eliminates the trouble of diseases to patients; moreover, the traditional Chinese medicine composition has the characteristics of obviously shortening the course of disease and having high cure rate; because the Chinese herbal medicine raw materials are adopted, the safety is high, no toxic or side effect is caused, the use is convenient, the wound caused by operation treatment is avoided, the pain of a patient can be obviously relieved, and the problems of large toxic or side effect and large wound existing in the existing method for treating the colitis are solved; the traditional Chinese medicine composition prepared by the embodiment of the invention is suitable for spleen loss of transportation and transformation, internal excess of damp-heat, long-term heat transformation of damp-heat, vein injury, qi and blood stagnation, internal excess of cold-damp, spleen and kidney yang deficiency and the like, obviously relieves the pain of patients, and obviously shortens the course of disease.
The traditional Chinese medicine composition is matched with the existing medicament for treating the colitis, has the effects of high cure rate, remarkably relieving the pain of patients and excellent clinical application curative effect.
While the preferred embodiments of the present invention have been described in detail, the present invention is not limited to the above embodiments, and various changes can be made without departing from the spirit of the present invention within the knowledge of those skilled in the art. And are neither required nor exhaustive of all embodiments. And obvious variations or modifications of the invention may be made without departing from the scope of the invention.
Claims (10)
1. The traditional Chinese medicine composition is characterized by comprising the following raw materials in parts by weight: 10-80 parts of clove, 10-100 parts of cinnamon, 10-100 parts of fructus evodiae, 10-100 parts of elecampane, 10-100 parts of gallnut and a proper amount of ginger juice.
2. The traditional Chinese medicine composition according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 30-60 parts of clove, 30-80 parts of cinnamon, 30-80 parts of fructus evodiae, 30-80 parts of elecampane, 30-80 parts of Chinese gall and a proper amount of ginger juice.
3. A method for preparing a Chinese medicinal composition as claimed in any one of claims 1-2, comprising the steps of:
1) weighing clove, cinnamon, fructus evodiae, elecampane and gallnut according to the weight parts, drying and then crushing to obtain powder;
2) adding ginger juice into the powder obtained in the step 1) and mixing to obtain the traditional Chinese medicine composition.
4. The method for preparing a Chinese medicinal composition according to claim 3, wherein the pulverization is carried out by grinding to 10-800 mesh to obtain the powder.
5. The method for preparing a Chinese medicinal composition according to claim 3, wherein the amount of the ginger juice is 0.01-1 times of the total weight of the clove, the cinnamon, the evodia rutaecarpa, the aucklandia root and the gallnut.
6. A Chinese medicinal composition prepared by the preparation method of claim 3, 4 or 5.
7. An external preparation characterized by comprising the Chinese medicinal composition as claimed in claim 1, 2 or 6 partially or entirely.
8. The external preparation for external use according to claim 7, wherein the dosage form of the external preparation for external use is a patch, a paste or a powder.
9. The external preparation for external use according to claim 8, wherein the dosage form of the external preparation for external use is a patch, and the application method is as follows: the topical medicine is applied to acupoints, which at least comprise Tianshu acupoint, Shangjuxu acupoint, Shenque acupoint and Sanyinjiao acupoint.
10. Use of a Chinese medicinal composition according to claim 1 or 2 or 6 in the manufacture of a medicament for the treatment of colitis and/or proctitis.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN115737763A (en) * | 2022-12-29 | 2023-03-07 | 杭州市第三人民医院 | Traditional Chinese medicine composition for relieving gastrointestinal reaction induced by macrolide medicines |
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| CN115737763B (en) * | 2022-12-29 | 2024-03-08 | 杭州市第三人民医院 | Traditional Chinese medicine composition for relieving gastrointestinal tract reaction induced by macrolide drugs |
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Application publication date: 20200630 |