CN111332510B - Air emptying method of liquid medicine filling device - Google Patents
Air emptying method of liquid medicine filling device Download PDFInfo
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- CN111332510B CN111332510B CN202010368574.XA CN202010368574A CN111332510B CN 111332510 B CN111332510 B CN 111332510B CN 202010368574 A CN202010368574 A CN 202010368574A CN 111332510 B CN111332510 B CN 111332510B
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
- B65B3/003—Filling medical containers such as ampoules, vials, syringes or the like
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
- B65B3/26—Methods or devices for controlling the quantity of the material fed or filled
- B65B3/28—Methods or devices for controlling the quantity of the material fed or filled by weighing
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B57/00—Automatic control, checking, warning, or safety devices
- B65B57/02—Automatic control, checking, warning, or safety devices responsive to absence, presence, abnormal feed, or misplacement of binding or wrapping material, containers, or packages
- B65B57/04—Automatic control, checking, warning, or safety devices responsive to absence, presence, abnormal feed, or misplacement of binding or wrapping material, containers, or packages and operating to control, or to stop, the feed of such material, containers, or packages
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B67—OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
- B67C—CLEANING, FILLING WITH LIQUIDS OR SEMILIQUIDS, OR EMPTYING, OF BOTTLES, JARS, CANS, CASKS, BARRELS, OR SIMILAR CONTAINERS, NOT OTHERWISE PROVIDED FOR; FUNNELS
- B67C3/00—Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus; Filling casks or barrels with liquids or semiliquids
- B67C3/02—Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus
- B67C3/22—Details
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B67—OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
- B67C—CLEANING, FILLING WITH LIQUIDS OR SEMILIQUIDS, OR EMPTYING, OF BOTTLES, JARS, CANS, CASKS, BARRELS, OR SIMILAR CONTAINERS, NOT OTHERWISE PROVIDED FOR; FUNNELS
- B67C3/00—Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus; Filling casks or barrels with liquids or semiliquids
- B67C3/02—Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus
- B67C3/22—Details
- B67C3/24—Devices for supporting or handling bottles
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B67—OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
- B67C—CLEANING, FILLING WITH LIQUIDS OR SEMILIQUIDS, OR EMPTYING, OF BOTTLES, JARS, CANS, CASKS, BARRELS, OR SIMILAR CONTAINERS, NOT OTHERWISE PROVIDED FOR; FUNNELS
- B67C3/00—Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus; Filling casks or barrels with liquids or semiliquids
- B67C3/02—Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus
- B67C3/22—Details
- B67C3/26—Filling-heads; Means for engaging filling-heads with bottle necks
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B67—OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
- B67C—CLEANING, FILLING WITH LIQUIDS OR SEMILIQUIDS, OR EMPTYING, OF BOTTLES, JARS, CANS, CASKS, BARRELS, OR SIMILAR CONTAINERS, NOT OTHERWISE PROVIDED FOR; FUNNELS
- B67C3/00—Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus; Filling casks or barrels with liquids or semiliquids
- B67C3/02—Bottling liquids or semiliquids; Filling jars or cans with liquids or semiliquids using bottling or like apparatus
- B67C3/22—Details
- B67C3/28—Flow-control devices, e.g. using valves
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- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Basic Packing Technique (AREA)
- Filling Of Jars Or Cans And Processes For Cleaning And Sealing Jars (AREA)
Abstract
The invention discloses an air evacuation method of a liquid medicine filling device, and relates to the field of filling. Meanwhile, a tailing filling mode can be set, corresponding formula parameters are set according to bottle specifications, the mode of automatically switching from a normal production mode to a tailing filling mode can be realized, the filling quantity of filling pumps is sequentially closed according to the quantity of tailing by monitoring the tailing quantity in real time, and the filling quantity of filling needle heads is gradually reduced until single-needle filling is realized, so that the filling qualified rate of products is ensured to the maximum extent, the utilization rate of tailing is improved, and the waste of liquid medicine is reduced to the minimum.
Description
Technical Field
The invention relates to the technical field of food and medicine packaging mechanical equipment, in particular to an air emptying method of a liquid medicine filling device.
Background
The liquid inlet of the liquid separating device of the existing liquid medicine filling device is arranged at the center of one end of the liquid separating device, and the emptying method before filling is as follows: the filling needle frame is lifted in the human-computer interface, the liquid receiving box is arranged below the filling needle frame, the liquid separating device is manually turned, the liquid outlet of the liquid separating device faces upwards, single emptying amount is set, and manual emptying operation is carried out by manually estimating emptying times. The emptying method is difficult to completely empty the liquid separating device, the filling precision is affected, more unqualified waste products are caused, and more liquid medicine is wasted.
The existing gas evacuation method of the liquid medicine filling device is characterized in that liquid medicine is evacuated in a manual operation mode, the liquid separating device is horizontally installed, a control valve of the liquid medicine is not subjected to intermittent control, so that more gas is remained in the liquid separator, the liquid separating device needs to be turned over to evacuate the gas, the whole operation is complex, the discharge of all small bubbles in the liquid separating device cannot be guaranteed, the residual bubbles possibly enter a filling pipeline in the filling process, and the precision control of the filling quantity is influenced. Manual mode operation equipment control system among the prior art, the suction evacuation of control pump divides the bubble of liquid device and filling line, but everybody's operation can't reappear, and efficiency is very low moreover, also can lead to more liquid medicine extravagant.
The quantity of the conventional tailing filling needles is fixed, the quantity of the filling needles cannot be adjusted when tailing filling is carried out, so that needle-filling decreasing type filling cannot be realized, and single-needle filling cannot be realized.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provides an air emptying method of a liquid medicine filling device, which can improve the filling precision, reduce the waste amount of liquid medicine and increase the product percent of pass.
In order to solve the technical problems, the invention adopts the following technical scheme:
the utility model provides a liquid medicine filling device air evacuation method, liquid medicine filling device includes medicine supply device, feed liquor valve, buffer tank, divides the liquid device and a plurality of needles of irritating of arranging side by side, medicine supply device and buffer tank pass through the feed liquor pipe connection, be equipped with the feed liquor valve on the feed liquor pipe, the buffer tank is connected with the inlet that divides the liquid device through first pipeline, the bottom that divides the liquid device is equipped with a plurality of liquid outlets along length direction, each liquid outlet and each irritate the needle and pass through a second pipe connection respectively, each second pipe all is equipped with the filling pump on the road, the liquid inlet is located divides the top of liquid device, liquid medicine filling device air evacuation method includes the following step:
s1: conveying a first group of medicine bottles to the position below each filling needle;
s2: the liquid medicine is injected into the liquid separating device, the liquid inlet valve is opened intermittently, the liquid medicine is injected into the liquid separating device intermittently until the liquid separating device is filled with the liquid medicine, and gas in the liquid separating device is discharged along the first pipeline;
s3: and (4) discharging the gas in the second pipeline, starting each filling pump, and discharging the gas in each second pipeline through a filling needle.
As a further improvement of the above technical solution:
the air evacuation method of the liquid medicine filling device further comprises the step S4: filling, starting a filling pump to fill liquid medicine into the medicine bottle; after the step S3, the first group of vials is removed, replaced with the second group of vials, and the process proceeds to step S4.
The step S4 includes the following sub-steps:
s41: the filling amount of each filling pump is calibrated, the medicine bottles below each filling needle are weighed, the weighing deviation of each medicine bottle is measured, whether the weighing deviation is qualified or not is judged, if the weighing deviation of each medicine bottle is qualified, the step S42 is carried out, and if the weighing deviation is unqualified, the filling amount of the corresponding filling pump is adjusted until the weighing deviation of each medicine bottle is qualified;
s42: and carrying out normal drug filling production.
The weighing deviation measuring device comprises a deviation measuring module, a first sensor and a second sensor, wherein the first sensor weighs the weight of each empty bottle and sends a weight signal of each empty bottle to the deviation measuring module, the second sensor weighs the total weight of each bottle filled with liquid medicine and sends a weight signal of each total bottle to the deviation measuring module, and the deviation measuring module calculates the weighing deviation of each medicine bottle according to the received signals and judges whether the weighing deviation is qualified or not.
The step S4 further includes the following sub-steps:
s43: when the liquid level in the buffer tank reaches the designated liquid level at the bottom, the liquid medicine amount in the liquid distribution device is measured in real time;
s44: when the amount of the liquid medicine in the liquid separating device is a first preset value, the number of filling needles is gradually reduced along with the reduction of the amount of the liquid medicine in the liquid separating device;
s45: and when the liquid medicine amount in the liquid separating device is a second preset value smaller than the first preset value, filling by adopting a single filling needle.
The first preset value is 50% of the total capacity of the liquid separating device, and the second preset value is 20% of the total capacity of the liquid separating device.
The liquid separating device is obliquely arranged.
The inclination angle a of the liquid separation device is 3-7 degrees.
The liquid medicine amount in the liquid separating device is measured by adopting a third sensor and a calculating module, the third sensor weighs the real-time weight of the buffer tank and sends a real-time weight signal to the calculating module, and the calculating module calculates the liquid medicine amount in the liquid separating device according to the received signal.
In step S3, for a second pipeline that is not completely empty, the filling pump on the second pipeline is turned on until the gas in the second pipeline is completely discharged.
Compared with the prior art, the invention has the advantages that:
the invention relates to an air evacuation method for a liquid medicine filling device, which comprises a medicine supply device, a liquid inlet valve, a buffer tank, a liquid separating device and a plurality of filling needles arranged side by side, wherein the medicine supply device is connected with the buffer tank through a liquid inlet pipeline, the liquid inlet pipeline is provided with the liquid inlet valve, the buffer tank is connected with a liquid inlet of the liquid separating device through a first pipeline, the bottom of the liquid separating device is provided with a plurality of liquid outlets along the length direction, each liquid outlet is respectively connected with each filling needle through a second pipeline, each second pipeline is provided with a filling pump, and the liquid inlet is arranged at the top of the liquid separating device, and the air evacuation method for the liquid medicine filling device comprises the following steps: s1: conveying a first group of medicine bottles to the position below each filling needle; s2: the liquid medicine is injected into the liquid separating device, the liquid inlet valve is opened intermittently, the liquid medicine is injected into the liquid separating device intermittently until the liquid separating device is filled with the liquid medicine, and gas in the liquid separating device is discharged along the first pipeline; s3: and (4) discharging the gas in the second pipeline, starting each filling pump, and discharging the gas in each second pipeline through a filling needle. The intermittent type is opened the feed liquor valve, can be to the middle disconnected liquid medicine that injects into of buffer tank, open the feed liquor valve for the first time to closing, inject the liquid medicine of predetermined amount into the buffer tank, the liquid medicine of this predetermined amount gets into the liquid device completely through first pipeline under the action of gravity in the buffer tank, be empty in first pipeline, partly gaseous rethread first pipeline in the liquid device gets into the buffer tank, so, open the feed liquor valve through interrupting many times, just can annotate liquid medicine with liquid device and first pipeline, the gas of liquid device and first pipeline is divided in the discharge, be convenient for follow-up accurate calculation of filling volume in each medicine bottle, improve the filling precision, avoid leading to the fact more unqualified waste because the filling precision is unqualified, thereby cause a large amount of liquid medicine extravagant.
Drawings
Fig. 1 is a schematic structural view of the liquid medicine filling apparatus of the present invention.
Fig. 2 is a schematic structural diagram of a liquid separating device of the liquid medicine filling device of the present invention.
Fig. 3 is an enlarged view at a in fig. 2.
Fig. 4 is a schematic structural view of a liquid inlet of a liquid separating device of the liquid medicine filling device of the present invention.
Fig. 5 is another schematic structural diagram of the liquid separating device of the liquid medicine filling device of the present invention.
The reference numerals in the figures denote:
1. a drug delivery device; 2. a liquid inlet valve; 3. a buffer tank; 4. a liquid separating device; 41. a liquid inlet; 42. a liquid outlet; 5. filling a needle; 6. a first pipeline; 7. a second pipeline; 71. a filling pump; 8. a deviation measuring device; 81. a first sensor; 82. a second sensor; 9. a third sensor.
Detailed Description
The invention will be described in further detail below with reference to the drawings and specific examples.
In the air evacuation method of the liquid medicine filling device of the present embodiment, as shown in fig. 1 to 4, the liquid medicine filling device includes a medicine supply device 1 and a liquid inlet valve 2, buffer tank 3, divide liquid device 4 and a plurality of needles 5 of irritating that arrange side by side, supply medicine device 1 and buffer tank 3 to pass through the feed liquor pipe connection, be equipped with feed liquor valve 2 on the feed liquor pipe, buffer tank 3 is connected through first pipeline 6 and liquid device 4's inlet 41, divide liquid device 4's bottom to be equipped with a plurality of liquid outlets 42 along length direction, each liquid outlet 42 is connected through a second pipeline 7 respectively with each irritate needle 5 (each liquid outlet 42 and each irritate needle 5 one-to-one, and each liquid outlet 42 that corresponds all is connected with second pipeline 7 between irritating needle 5), all be equipped with filling pump 71 on each second pipeline 7, inlet 41 locates the top of dividing liquid device 4, liquid medicine filling device air evacuation method includes the following step:
s1: conveying a first group of medicine bottles to the position below each filling needle 5; specifically, the medicine bottle is automatically conveyed below the filling needle 5 through the bottle conveying device, so that the production efficiency is improved.
S2: the liquid medicine is injected into the liquid separating device 4, the liquid inlet valve 2 is opened intermittently, the liquid medicine is injected into the liquid separating device 4 intermittently until the liquid separating device 4 is filled with the liquid medicine, and the gas in the liquid separating device 4 is discharged along the first pipeline 6; specifically, the liquid inlet valve 2 is opened intermittently, so that the liquid medicine can be injected into the buffer tank 3 intermittently, and if the liquid inlet valve 2 is opened, the liquid medicine is injected into the buffer tank 3, and the liquid medicine in the buffer tank 3 enters the liquid separating device 4 through the first pipeline 6; close feed liquor valve 2, divide the partial gas in the liquid device 4 to discharge to buffer tank 3 through first pipeline 6, so, through being interrupted to open feed liquor valve 2 many times, just can fill up the liquid medicine in liquid device 4 and first pipeline 6, the gas in discharge liquid device 4 and the first pipeline 6 of dividing, the accurate calculation of filling volume in the follow-up each medicine bottle of being convenient for improves the filling precision, avoid causing more unqualified waste product because the filling precision is unqualified, thereby cause a large amount of liquid medicine extravagant.
S3: and (3) discharging the gas in the second pipeline 7, starting each filling pump 71, pumping the liquid medicine in the liquid separating device 4 to each filling needle 5, and discharging the gas in each second pipeline 7 through the filling needle 5 under the squeezing and pushing action of the liquid medicine, so that the liquid medicine entering the medicine bottle does not carry gas when the medicine bottle is normally filled subsequently, and the filling precision of the filling amount in each subsequent medicine bottle is further improved.
In this embodiment, the air evacuation method for the liquid medicine filling device further includes step S4: filling, starting a filling pump 71 to fill liquid medicine into the medicine bottle; after step S3, the first group of vials is removed (since the first group of vials are filled with the empty medical solution, which does not meet the product requirements and requires a waste treatment, i.e., a reject treatment), and replaced with a second group of vials, and then step S4 is performed. Specifically, each filling pump 71 is started, the liquid medicine in the liquid separating device 4 is pumped out to the first group of medicine bottles through the second pipeline 7 where each filling pump 71 is located, and air in the second pipeline 7 is squeezed out during the pumping-out process of the liquid medicine, so that the gas in the second pipeline 7 is discharged.
In this embodiment, step S4 includes the following sub-steps:
s41: calibrating the filling amount of each filling pump 71, weighing the medicine bottles below each filling needle 5, measuring the weighing deviation of each medicine bottle, judging whether the weighing deviation is qualified, if the weighing deviation of each medicine bottle is qualified (the weighing deviation is qualified, the filling of the liquid medicine in the medicine bottle is qualified, namely the filling amount of the filling pump 71 corresponding to the medicine bottle is qualified), performing step S42, and if the weighing deviation of each medicine bottle is unqualified, adjusting the filling amount of the corresponding filling pump 71 until the weighing deviation of each medicine bottle is qualified;
s42: and carrying out normal drug filling production. The normal medicine filling production is that the medicine liquid filling of the next medicine bottles of each group is realized through the reciprocating motion of each filling pump 71, and the requirement of the product percent of pass can be met.
In this embodiment, the deviation measuring device 8 is used to measure the weighing deviation of each medicine bottle, the deviation measuring device 8 includes a deviation measuring module, a first sensor 81 and a second sensor 82, the first sensor 81 weighs the weight of each empty bottle and sends each empty bottle weight signal to the deviation measuring module, the second sensor 82 weighs the total bottle weight filled with the liquid medicine and sends each total bottle weight signal to the deviation measuring module, and the deviation measuring module calculates the weighing deviation of each medicine bottle according to the received signal and determines whether the weighing deviation is qualified. If the filling pump 71 is unqualified in filling amount, the deviation measuring module sends an adjusting signal to the unqualified filling pump 71, so that the unqualified filling pump 71 is adjusted to be qualified in filling amount.
In this embodiment, step S4 further includes the following sub-steps:
s43: when the liquid level in the buffer tank 3 reaches the designated liquid level at the bottom, the liquid medicine amount in the liquid separation device 4 is measured in real time;
s44: when the amount of the liquid medicine in the liquid separating device 4 is a first preset value, the number of the filling needles 5 is gradually reduced along with the reduction of the amount of the liquid medicine in the liquid separating device 4; specifically, divide liquid device 4 slope setting and make liquid inlet 41 of dividing liquid device 4 be located the top of dividing liquid device 4, and divide liquid device 4 for dividing the liquid pipe, the liquid medicine in dividing liquid device 4 collects to the bottom, along with dividing the reduction of liquid medicine volume in liquid device 4, filling pump 71 that the liquid outlet 42 that is arranged in dividing liquid device 4 liquid level top corresponds has not had the liquid medicine and can takes out, consequently, can stop using this filling pump 71 to correspond irritate needle 5 to along with dividing the reduction of liquid level in the liquid device 4, reduce the use quantity of irritating needle 5 gradually.
S45: and when the liquid medicine amount in the liquid separating device 4 is a second preset value smaller than the first preset value, filling by adopting a single filling needle 5, namely filling by adopting the filling needle 5 at the lowest part of the liquid separating device 4.
In the present embodiment, the first predetermined value is preferably 50% of the total capacity of the liquid separating means 4, and the second predetermined value is preferably 20% of the total capacity of the liquid separating means 4. So that the waste amount of the liquid medicine is minimized.
In this example, as shown in fig. 1, the inclination angle a of the liquid separator 4 was 3 ° to 7 °. The inclination angle a of the liquid separating device 4 is in the range of 3-7 degrees, and the waste amount of the liquid medicine is less. Divide liquid device 4 to be the tubulose, divide the bottom slope setting of liquid device 4 to make liquid inlet 41 eccentric locate the upper end (as shown in fig. 3 and fig. 4) of dividing liquid device 4, make divide liquid device 4 when the tail liquid filling, can be according to the use amount of liquid medicine volume adjustment irritate needle 5 among the liquid device 4, up to the single needle 5 filling of irritating that adopts the liquid device 4 below liquid outlet 42 to correspond, make the filling of last bottle medicine bottle accomplish, thereby reduced remaining liquid medicine volume in dividing liquid device 4.
In this embodiment, the liquid amount in the liquid separating device 4 is measured by using the third sensor 9 and the calculating module, the third sensor 9 weighs the real-time weight of the buffer tank 3 and sends the real-time weight signal to the calculating module, and the calculating module calculates the liquid amount in the liquid separating device 4 according to the received signal. The third sensor 9 weighs the real-time weight of the buffer tank 3 and sends a real-time weight signal to the calculation module, and the calculation module calculates the amount of the liquid medicine in the liquid separation device 4 according to the received signal so as to facilitate selection of the usage amount of the filling needle 5.
In this embodiment, in step S3, the filling pump 71 on the second pipeline 7 is designated to open the second pipeline 7 that is not completely emptied, and the chemical liquid in the liquid separation device 4 is further drawn into the second pipeline 7 by the reciprocating motion of the filling pump 71 until the chemical liquid completely pushes out the gas in the second pipeline 7.
Of course, in other embodiments, as shown in fig. 5, the inner bottom surface of the liquid containing cavity in the liquid separating device 4 may be configured as a V-shape or a curved surface with a concave middle portion, and the liquid inlet 41 is disposed at a high position of the top wall of the liquid containing cavity in the liquid separating device 4.
According to the air evacuation method for the liquid medicine filling device, the liquid inlet of the liquid separating device 4 is of a top opening structure, liquid medicine is injected into the liquid separating device 4, the liquid inlet valve 2 is opened discontinuously, the liquid medicine is injected into the liquid separating device 4 discontinuously until the liquid separating device 4 is filled with the liquid medicine, then the liquid medicine below the liquid separating device 4 is evacuated, the evacuation process is automatic, manual operation is not needed, the whole filling system does not have residual gas, and the filling precision and the qualification rate are high. Meanwhile, a tailing filling mode can be set, corresponding formula parameters are set according to bottle specifications, the mode of automatically switching from a normal production mode to a tailing filling mode can be realized, the filling quantity of filling pumps is sequentially closed according to the quantity of tailing by monitoring the tailing quantity in real time, and the filling quantity of filling needle heads is gradually reduced until single-needle filling is realized, so that the filling qualified rate of products is ensured to the maximum extent, the utilization rate of tailing is improved, and the waste of liquid medicine is reduced to the minimum.
Although the present invention has been described with reference to the preferred embodiments, it is not intended to be limited thereto. Those skilled in the art can make numerous possible variations and modifications to the present invention, or modify equivalent embodiments to equivalent variations, without departing from the scope of the invention, using the teachings disclosed above. Therefore, any simple modification, equivalent change and modification made to the above embodiments according to the technical spirit of the present invention should fall within the protection scope of the technical scheme of the present invention, unless the technical spirit of the present invention departs from the content of the technical scheme of the present invention.
Claims (10)
1. An air evacuation method for a liquid medicine filling device is characterized in that: the liquid medicine filling device comprises a medicine supply device (1), a liquid inlet valve (2), a buffer tank (3), a liquid separation device (4) and a plurality of filling needles (5) arranged side by side, wherein the medicine supply device (1) and the buffer tank (3) are connected through a liquid inlet pipeline, the liquid inlet pipeline is provided with the liquid inlet valve (2), the buffer tank (3) is connected with a liquid inlet (41) of the liquid separation device (4) through a first pipeline (6), the bottom of the liquid separation device (4) is provided with a plurality of liquid outlets (42) along the length direction, each liquid outlet (42) is connected with each filling needle (5) through a second pipeline (7), each second pipeline (7) is provided with a filling pump (71), the liquid inlet (41) is arranged at the top of the liquid separation device (4), and the air emptying method of the liquid medicine filling device comprises the following steps:
s1: conveying a first group of medicine bottles to the lower part of each filling needle (5);
s2: the liquid medicine is injected into the liquid separating device (4), the liquid inlet valve (2) is opened intermittently, the liquid medicine is injected into the liquid separating device (4) intermittently until the liquid separating device (4) is filled with the liquid medicine, and gas in the liquid separating device (4) is discharged along the first pipeline (6);
s3: and (3) exhausting the gas in the second pipelines (7), starting each filling pump (71), and exhausting the gas in each second pipeline (7) through the filling needle (5).
2. The liquid medicine filling device air evacuation method according to claim 1, characterized in that: the air evacuation method of the liquid medicine filling device further comprises the step S4: filling, starting a filling pump (71) to fill liquid medicine into the medicine bottle; after the step S3, the first group of vials is removed, replaced with the second group of vials, and the process proceeds to step S4.
3. The liquid medicine filling device air evacuation method according to claim 2, characterized in that: the step S4 includes the following sub-steps:
s41: the filling amount of each filling pump (71) is calibrated, the medicine bottles below each filling needle (5) are weighed, the weighing deviation of each medicine bottle is measured, whether the weighing deviation is qualified or not is judged, if the weighing deviation of each medicine bottle is qualified, the step S42 is carried out, and if the weighing deviation is unqualified, the filling amount of the corresponding filling pump (71) is adjusted until the weighing deviation of each medicine bottle is qualified;
s42: and carrying out normal drug filling production.
4. The liquid medicine filling device air evacuation method according to claim 3, wherein: the weighing deviation of each medicine bottle is measured by adopting a deviation measuring device (8), the deviation measuring device (8) comprises a deviation measuring module, a first sensor (81) and a second sensor (82), the first sensor (81) weighs the weight of each empty bottle and sends each empty bottle weight signal to the deviation measuring module, the second sensor (82) weighs the total bottle weight filled with the medicine liquid and sends each total bottle weight signal to the deviation measuring module, and the deviation measuring module calculates the weighing deviation of each medicine bottle according to the received signals and judges whether the medicine bottle is qualified or not.
5. The liquid medicine filling device air evacuation method according to claim 3, wherein: the step S4 further includes the following sub-steps:
s43: when the liquid level in the buffer tank (3) reaches the designated liquid level at the bottom, the liquid medicine amount in the liquid distribution device (4) is measured in real time;
s44: when the amount of the liquid medicine in the liquid separating device (4) is a first preset value, the number of the filling needles (5) is gradually reduced along with the reduction of the amount of the liquid medicine in the liquid separating device (4);
s45: and when the liquid medicine amount in the liquid separating device (4) is a second preset value smaller than the first preset value, filling by adopting a single filling needle (5).
6. The liquid medicine filling device air evacuation method according to claim 5, wherein: the first predetermined value is 50% of the total capacity of the liquid separating device (4), and the second predetermined value is 20% of the total capacity of the liquid separating device (4).
7. The liquid medicine filling device air evacuation method according to claim 5, wherein: the liquid separating device (4) is obliquely arranged.
8. The liquid medicine filling device air evacuation method according to claim 7, wherein: the inclination angle a of the liquid separation device (4) is 3-7 degrees.
9. The liquid medicine filling device air evacuation method according to claim 5, wherein: the liquid medicine amount in the liquid separating device (4) is measured by adopting a third sensor (9) and a calculating module, the third sensor (9) weighs the real-time weight of the buffer tank (3) and sends a real-time weight signal to the calculating module, and the calculating module calculates the liquid medicine amount in the liquid separating device (4) according to the received signal.
10. The liquid medicine filling apparatus air evacuation method according to any one of claims 1 to 9, characterized in that: in the step S3, for the second pipeline (7) which is not completely emptied, the filling pump (71) on the second pipeline (7) is turned on until the gas in the second pipeline (7) is completely discharged.
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| CN111846307B (en) * | 2020-08-05 | 2021-09-21 | 楚天科技股份有限公司 | Liquid medicine filling method |
| CN111792066A (en) * | 2020-08-05 | 2020-10-20 | 楚天科技股份有限公司 | Liquid medicine filling system capable of reducing liquid medicine loss and filling method thereof |
| CN112977908B (en) * | 2021-03-02 | 2022-12-02 | 康宁杰瑞(吉林)生物科技有限公司 | Filling and plugging machine and filling method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US20140109526A1 (en) * | 2012-10-23 | 2014-04-24 | Roush Life Sciences, Llc | Carboy With Permanent Closure and Method of Filling a Carboy |
| CN203545650U (en) * | 2013-09-09 | 2014-04-16 | 楚天科技股份有限公司 | Medicine liquid filling device |
| CN107840297B (en) * | 2016-09-18 | 2020-03-24 | 武汉中原瑞德生物制品有限责任公司 | Liquid filling system and liquid medicine filling machine with same |
| CN207986647U (en) * | 2017-10-23 | 2018-10-19 | 沈阳康博源生物科技有限公司 | Liquid preparation sub-packaging system |
| CN109592623A (en) * | 2019-02-02 | 2019-04-09 | 长沙康欧创新科技有限公司 | A kind of liquid-filling machine |
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