CN111329889A - Castration agent containing traditional Chinese medicine extract for dogs and preparation method and application thereof - Google Patents

Castration agent containing traditional Chinese medicine extract for dogs and preparation method and application thereof Download PDF

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CN111329889A
CN111329889A CN202010275491.6A CN202010275491A CN111329889A CN 111329889 A CN111329889 A CN 111329889A CN 202010275491 A CN202010275491 A CN 202010275491A CN 111329889 A CN111329889 A CN 111329889A
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extract
dogs
castrating
agent
chinese medicine
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钟伟萍
夏芳
吴成剑
张志阳
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Sichuan Hengbo Biotechnology Co ltd
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Sichuan Hengbo Biotechnology Co ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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Abstract

The invention discloses a dog castrating agent containing traditional Chinese medicine extract, a preparation method and application thereof, wherein the dog castrating agent comprises the following components in parts by weight: 5-10% of procaine hydrochloride, 5-8% of phenol, 1-4% of ephedra extract, 1-4% of artemisia vulgaris extract, 1-4% of sodium chloride, 2-6% of polyethylene glycol, 2-6% of calcium chloride, 1-2% of potassium sorbate and the balance of water. The castrating agent is used for castrating the dogs, is convenient to operate, low in labor intensity, capable of greatly improving working efficiency, capable of effectively reducing cost and greatly relieving the pain of the dogs. The castration agent disclosed by the invention is specially added with traditional Chinese medicine components, so that the influence of castration of dogs on the normal growth of the dogs can be better reduced, the success rate is more than 99%, the castration agent is high in safety, free of toxic and side effects and adverse sequelae, and wide in development and application prospects.

Description

Castration agent containing traditional Chinese medicine extract for dogs and preparation method and application thereof
Technical Field
The invention relates to the technical field of veterinary medicines, in particular to a dog castrating agent containing traditional Chinese medicine extracts, and a preparation method and application thereof.
Background
Castration refers to the removal or loss of sexual function of the reproductive system of an animal by means other than surgery. Aims to eliminate the libido and reproductive capacity of livestock, so that the sexual emotion of the livestock becomes mild and endurable, and the management is convenient; the meat quality of the meat animals is improved, and the yield is increased; and can also control the mating behavior in the livestock group, thereby being beneficial to the propagation and breeding of improved varieties.
The traditional method mostly adopts surgical removal, but the surgical method has the disadvantages of complicated operation, easy bleeding, easy infection, easy tetanus and malignant edema, high waste rate, high labor intensity and high cost, and needs a long recovery period after the surgery, so the normal growth of animals is greatly influenced. Therefore, it is of great significance to develop more simple and low-cost castration methods.
Disclosure of Invention
The invention mainly solves the technical problem of providing the dog castrating agent containing the traditional Chinese medicine extract, which can relieve the pain of operative castration of dogs, and has convenient operation and low cost.
In order to solve the technical problems, the invention adopts a technical scheme that:
provides a castration agent for dogs containing traditional Chinese medicine extract, which comprises the following components: procaine hydrochloride, phenol, sodium chloride, polyethylene glycol, calcium chloride, potassium sorbate and water.
Further, the castrating agent comprises the following components in parts by weight: 5-10% of procaine hydrochloride, 5-8% of phenol, 1-4% of sodium chloride, 2-6% of polyethylene glycol, 2-6% of calcium chloride, 1-2% of potassium sorbate and the balance of water.
Further, the castrating agent also comprises an ephedra extract and a artemisia vulgaris extract.
Further, the castrating agent comprises the following components in parts by weight: 5-10% of procaine hydrochloride, 5-8% of phenol, 1-4% of ephedra extract, 1-4% of artemisia vulgaris extract, 1-4% of sodium chloride, 2-6% of polyethylene glycol, 2-6% of calcium chloride, 1-2% of potassium sorbate and the balance of water.
Further, the herba ephedrae extract in the castrating agent: the mass ratio of the artemisia annua extract is 1: 1.
further, the preparation method of the ephedra extract and the artemisia vulgaris extract comprises the following steps: decocting herba Ephedrae or herba Artemisiae Annuae in water for three times, mixing decoctions, filtering to remove solid, and removing solvent.
Furthermore, the time for each decoction is 3-4 h.
The invention also provides a preparation method of the castrating agent containing the traditional Chinese medicine extract for dogs, which comprises the following steps: mixing all the materials.
Further, the method also comprises the steps of packaging and sterilizing.
The invention also provides application of the castrating agent containing the traditional Chinese medicine extract for dogs in preparation of products for castrating the dogs.
The invention has the beneficial effects that:
(1) the castrating agent has a success rate of more than 99 percent, and has high safety, no toxic or side effect and no adverse sequelae.
(2) The castration agent is specially added with traditional Chinese medicine components, so that the influence of castration on the normal growth of the dog can be better reduced, and the dog has no obvious discomfort or discomfort in a short period after castration.
(3) The castrating agent is used for castrating the dogs, is convenient to operate, low in labor intensity, capable of greatly improving working efficiency, capable of effectively reducing cost and greatly relieving the pain of the dogs.
Detailed Description
The technical solutions of the present invention are described clearly and completely below, and it is obvious that the described embodiments are some, not all embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
Preparation of ephedra extract:
(1) pulverizing herba Ephedrae, adding herba Ephedrae powder into decocting device, and decocting with water;
(2) decocting for 3 times, each for 3 hr, mixing decoctions, filtering to remove solid impurities, and evaporating the filtrate to dryness to obtain herba Ephedrae extract.
Preparation of the artemisia annua extract:
(1) pulverizing Artemisia ordosica with a pulverizer, adding Artemisia ordosica powder into a decocting device, and decocting with water;
(2) decocting for 3 times, each for 3 hr, mixing decoctions, filtering to remove solid impurities, and evaporating the filtrate to dryness to obtain Artemisia ordosica L extract.
The invention relates to a preparation of a castrating agent containing traditional Chinese medicine extracts for dogs, which comprises the following steps:
5g of procaine hydrochloride, 5g of phenol, 1g of ephedra extract, 1g of artemisia vulgaris extract, 4g of sodium chloride, 6g of polyethylene glycol, 6g of calcium chloride, 2g of potassium sorbate and 70g of deionized water are uniformly mixed, packaged and sterilized to obtain the castration agent for dogs containing the traditional Chinese medicine extract.
Example 2
Preparation of ephedra extract:
(1) pulverizing herba Ephedrae, adding herba Ephedrae powder into decocting device, and decocting with water;
(2) decocting for 3 times, each for 4 hr, mixing decoctions, filtering to remove solid impurities, and evaporating the filtrate to dryness to obtain herba Ephedrae extract.
Preparation of the artemisia annua extract:
(1) pulverizing Artemisia ordosica with a pulverizer, adding Artemisia ordosica powder into a decocting device, and decocting with water;
(2) decocting for 3 times, each for 4 hr, mixing decoctions, filtering to remove solid impurities, and evaporating the filtrate to dryness to obtain Artemisia ordosica L extract.
The invention relates to a preparation of a castrating agent containing traditional Chinese medicine extracts for dogs, which comprises the following steps:
the castration agent for dogs containing the traditional Chinese medicine extract is prepared by uniformly mixing 10g of procaine hydrochloride, 8g of phenol, 4g of ephedra extract, 4g of artemisia annua extract, 1g of sodium chloride, 2g of polyethylene glycol, 2g of calcium chloride, 1g of potassium sorbate and 68g of deionized water, packaging and sterilizing.
Example 3
Preparation of ephedra extract:
(1) pulverizing herba Ephedrae, adding herba Ephedrae powder into decocting device, and decocting with water;
(2) decocting for 3 times, each for 3 hr, mixing decoctions, filtering to remove solid impurities, and evaporating the filtrate to dryness to obtain herba Ephedrae extract.
Preparation of the artemisia annua extract:
(1) pulverizing Artemisia ordosica with a pulverizer, adding Artemisia ordosica powder into a decocting device, and decocting with water;
(2) decocting for 3 times, each for 4 hr, mixing decoctions, filtering to remove solid impurities, and evaporating the filtrate to dryness to obtain Artemisia ordosica L extract.
The invention relates to a preparation of a castrating agent containing traditional Chinese medicine extracts for dogs, which comprises the following steps:
the castration agent for dogs containing the traditional Chinese medicine extract is prepared by uniformly mixing 6g of procaine hydrochloride, 6g of phenol, 3g of ephedra extract, 3g of artemisia annua extract, 2g of sodium chloride, 3g of polyethylene glycol, 3g of calcium chloride, 1.5g of potassium sorbate and 72.5g of deionized water, packaging and sterilizing.
Example 4
Preparation of ephedra extract:
(1) pulverizing herba Ephedrae, adding herba Ephedrae powder into decocting device, and decocting with water;
(2) decocting for 3 times, each for 4 hr, mixing decoctions, filtering to remove solid impurities, and evaporating the filtrate to dryness to obtain herba Ephedrae extract.
Preparation of the artemisia annua extract:
(1) pulverizing Artemisia ordosica with a pulverizer, adding Artemisia ordosica powder into a decocting device, and decocting with water;
(2) decocting for 3 times, each for 3 hr, mixing decoctions, filtering to remove solid impurities, and evaporating the filtrate to dryness to obtain Artemisia ordosica L extract.
The invention relates to a preparation of a castrating agent containing traditional Chinese medicine extracts for dogs, which comprises the following steps:
7g of procaine hydrochloride, 5g of phenol, 3g of ephedra extract, 3g of artemisia vulgaris extract, 1g of sodium chloride, 2g of polyethylene glycol, 2g of calcium chloride, 1g of potassium sorbate and 76g of deionized water are uniformly mixed, packaged and sterilized to obtain the castration agent for dogs containing the traditional Chinese medicine extract.
Example 5
Preparation of ephedra extract:
(1) pulverizing herba Ephedrae, adding herba Ephedrae powder into decocting device, and decocting with water;
(2) decocting for 3 times, each for 3 hr, mixing decoctions, filtering to remove solid impurities, and evaporating the filtrate to dryness to obtain herba Ephedrae extract.
Preparation of the artemisia annua extract:
(1) pulverizing Artemisia ordosica with a pulverizer, adding Artemisia ordosica powder into a decocting device, and decocting with water;
(2) decocting for 3 times, each for 3 hr, mixing decoctions, filtering to remove solid impurities, and evaporating the filtrate to dryness to obtain Artemisia ordosica L extract.
The invention relates to a preparation of a castrating agent containing traditional Chinese medicine extracts for dogs, which comprises the following steps:
the castration agent for dogs containing the traditional Chinese medicine extract is prepared by uniformly mixing 6g of procaine hydrochloride, 6g of phenol, 2g of ephedra extract, 2g of artemisia annua extract, 2g of sodium chloride, 2g of polyethylene glycol, 3g of calcium chloride, 2g of potassium sorbate and 75g of deionized water, packaging and sterilizing.
Example 6
Preparation of ephedra extract:
(1) pulverizing herba Ephedrae, adding herba Ephedrae powder into decocting device, and decocting with water;
(2) decocting for 3 times, each for 3 hr, mixing decoctions, filtering to remove solid impurities, and evaporating the filtrate to dryness to obtain herba Ephedrae extract.
Preparation of the artemisia annua extract:
(1) pulverizing Artemisia ordosica with a pulverizer, adding Artemisia ordosica powder into a decocting device, and decocting with water;
(2) decocting for 3 times, each for 3 hr, mixing decoctions, filtering to remove solid impurities, and evaporating the filtrate to dryness to obtain Artemisia ordosica L extract.
The invention relates to a preparation of a castrating agent containing traditional Chinese medicine extracts for dogs, which comprises the following steps:
5g of procaine hydrochloride, 8g of phenol, 1g of ephedra extract, 1g of artemisia vulgaris extract, 2g of sodium chloride, 3g of polyethylene glycol, 4g of calcium chloride, 1g of potassium sorbate and 75g of deionized water are uniformly mixed, packaged and sterilized to obtain the castration agent for dogs containing the traditional Chinese medicine extract.
Example 7
Preparation of ephedra extract:
(1) pulverizing herba Ephedrae, adding herba Ephedrae powder into decocting device, and decocting with water;
(2) decocting for 3 times, each for 3 hr, mixing decoctions, filtering to remove solid impurities, and evaporating the filtrate to dryness to obtain herba Ephedrae extract.
Preparation of the artemisia annua extract:
(1) pulverizing Artemisia ordosica with a pulverizer, adding Artemisia ordosica powder into a decocting device, and decocting with water;
(2) decocting for 3 times, each for 3 hr, mixing decoctions, filtering to remove solid impurities, and evaporating the filtrate to dryness to obtain Artemisia ordosica L extract.
The invention relates to a preparation of a castrating agent containing traditional Chinese medicine extracts for dogs, which comprises the following steps:
5g of procaine hydrochloride, 5g of phenol, 4g of ephedra extract, 4g of artemisia vulgaris extract, 2g of sodium chloride, 2g of polyethylene glycol, 2g of calcium chloride, 2g of potassium sorbate and 74g of deionized water are uniformly mixed, packaged and sterilized to obtain the castration agent for dogs containing the traditional Chinese medicine extract.
Example 8
Preparation of ephedra extract:
(1) pulverizing herba Ephedrae, adding herba Ephedrae powder into decocting device, and decocting with water;
(2) decocting for 3 times, each for 3 hr, mixing decoctions, filtering to remove solid impurities, and evaporating the filtrate to dryness to obtain herba Ephedrae extract.
Preparation of the artemisia annua extract:
(1) pulverizing Artemisia ordosica with a pulverizer, adding Artemisia ordosica powder into a decocting device, and decocting with water;
(2) decocting for 3 times, each for 3 hr, mixing decoctions, filtering to remove solid impurities, and evaporating the filtrate to dryness to obtain Artemisia ordosica L extract.
The invention relates to a preparation of a castrating agent containing traditional Chinese medicine extracts for dogs, which comprises the following steps:
7g of procaine hydrochloride, 5g of phenol, 3g of ephedra extract, 3g of artemisia vulgaris extract, 3g of sodium chloride, 3g of polyethylene glycol, 3g of calcium chloride, 1g of potassium sorbate and 72g of deionized water are uniformly mixed, packaged and sterilized to obtain the castration agent for dogs containing the traditional Chinese medicine extract.
Example 9
Preparation of ephedra extract:
(1) pulverizing herba Ephedrae, adding herba Ephedrae powder into decocting device, and decocting with water;
(2) decocting for 3 times, each for 3 hr, mixing decoctions, filtering to remove solid impurities, and evaporating the filtrate to dryness to obtain herba Ephedrae extract.
Preparation of the artemisia annua extract:
(1) pulverizing Artemisia ordosica with a pulverizer, adding Artemisia ordosica powder into a decocting device, and decocting with water;
(2) decocting for 3 times, each for 3 hr, mixing decoctions, filtering to remove solid impurities, and evaporating the filtrate to dryness to obtain Artemisia ordosica L extract.
The invention relates to a preparation of a castrating agent containing traditional Chinese medicine extracts for dogs, which comprises the following steps:
the castration agent for dogs containing the traditional Chinese medicine extract is prepared by uniformly mixing 6g of procaine hydrochloride, 6g of phenol, 2g of ephedra extract, 2g of artemisia annua extract, 3g of sodium chloride, 3g of polyethylene glycol, 3g of calcium chloride, 1g of potassium sorbate and 74g of deionized water, packaging and sterilizing.
The using method comprises the following steps: an operator holds the testis of an animal with the left hand, holds the injector connected with the special needle with the right hand, injects the medicine from the lower end of the testis to the upper end of the testis from the vertical axis puncture needle to four fifths of the upper end of the testis from the vertical axis puncture needle, and then takes the needle.
The castrating agent has a success rate of more than 99 percent, and has high safety, no toxic or side effect and no adverse sequelae. The castration agent is specially added with traditional Chinese medicine components, so that the influence of castration on the normal growth of the dog can be better reduced, and the dog has no obvious discomfort or discomfort in a short period after castration.
The castrating agent is used for castrating the dogs, is convenient to operate, low in labor intensity, capable of greatly improving working efficiency, capable of effectively reducing cost and greatly relieving the pain of the dogs.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (10)

1. A castration agent for dogs containing traditional Chinese medicine extracts is characterized by comprising the following components: procaine hydrochloride, phenol, sodium chloride, polyethylene glycol, calcium chloride, potassium sorbate and water.
2. The castrating agent according to claim 1, comprising the following components in parts by weight: 5-10% of procaine hydrochloride, 5-8% of phenol, 1-4% of sodium chloride, 2-6% of polyethylene glycol, 2-6% of calcium chloride, 1-2% of potassium sorbate and the balance of water.
3. The castrating agent of claim 1, further comprising an extract of ephedra, an extract of artemisia nivea.
4. The castrating agent according to claim 3, comprising the following components in parts by weight: 5-10% of procaine hydrochloride, 5-8% of phenol, 1-4% of ephedra extract, 1-4% of artemisia vulgaris extract, 1-4% of sodium chloride, 2-6% of polyethylene glycol, 2-6% of calcium chloride, 1-2% of potassium sorbate and the balance of water.
5. The castrating agent of claim 3 wherein the formulation comprises an extract of Ephedra sinica Stapf: the mass ratio of the artemisia annua extract is 1: 1.
6. the castrating agent as claimed in any one of claims 3 to 5, wherein the preparation method of the ephedra extract and the artemisia vulgaris extract comprises: decocting herba Ephedrae or herba Artemisiae Annuae in water for three times, mixing decoctions, filtering to remove solid, and removing solvent.
7. The castrating agent according to claim 3, wherein the time for each decoction is 3 to 4 hours.
8. A preparation method of the castrating agent containing the traditional Chinese medicine extract for the dogs, which is characterized by comprising the following steps: mixing all the materials.
9. The method of claim 8, further comprising the steps of packaging and sterilizing.
10. Use of the castration agent for dogs containing the traditional Chinese medicine extract as claimed in any one of claims 1 to 7 in preparation of a product for castration of dogs.
CN202010275491.6A 2020-04-09 2020-04-09 Castration agent containing traditional Chinese medicine extract for dogs and preparation method and application thereof Pending CN111329889A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1131558A (en) * 1995-11-27 1996-09-25 周天元 Injection for animal and livestock emasculation
CN103784484A (en) * 2014-01-24 2014-05-14 河南科技大学 Castration liquid for dogs and preparation method thereof
CN103784485A (en) * 2014-01-24 2014-05-14 河南科技大学 Castration liquid for livestock and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1131558A (en) * 1995-11-27 1996-09-25 周天元 Injection for animal and livestock emasculation
CN103784484A (en) * 2014-01-24 2014-05-14 河南科技大学 Castration liquid for dogs and preparation method thereof
CN103784485A (en) * 2014-01-24 2014-05-14 河南科技大学 Castration liquid for livestock and preparation method thereof

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Application publication date: 20200626