CN111329490A - Non-invasive anti-interference blood glucose detector and method for detecting blood glucose by using same - Google Patents
Non-invasive anti-interference blood glucose detector and method for detecting blood glucose by using same Download PDFInfo
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Abstract
The invention provides a non-invasive anti-interference blood sugar detector, which comprises a first electrode, a second electrode, a third electrode and a fourth electrode, wherein the first electrode, the second electrode, the third electrode and the fourth electrode are exposed outside a shell and are formed by conductors; and a working circuit; the first electrode, the third electrode and the fourth electrode are arranged at one end of the shell to form a first probe, and the second electrode is independently arranged at the other end of the shell to form a second probe; the first electrode is connected with the second electrode; the third electrode is connected with the fourth electrode; the operating circuit includes: the device comprises a signal processing module, a storage unit, a microprocessor and a power supply module; the first electrode, the second electrode, the third electrode and the fourth electrode are connected with the signal processing module, the microprocessor is connected with the signal processing module, the storage unit is connected with the microprocessor, and the power supply module supplies power to all the elements through a circuit. The invention can reduce external interference, capture more accurate data and measure more accurate and real blood sugar value.
Description
Technical Field
The invention relates to the field of medical instruments, in particular to a non-invasive anti-interference blood sugar detector and a method for detecting blood sugar by using the same.
Background
Currently, all countries around the world have focused on the technical development of non-invasive (blood prick free) blood glucose monitors, and generally, electronic technology is used to acquire physiological data of a human body through the skin of the human body. Although the known single electronic technology can see the electronic signal changes of the skin, experiments show that the changes are very slight and are easily interfered by the external environment, so that the accuracy of the detected data cannot be guaranteed and the practical significance is not achieved.
In addition, the non-invasive blood glucose detector detects only electronic data, and the electronic data is lack of authenticity before an actual data calibration means is not available, so that the real blood glucose value of a human body cannot be directly calculated. At present, various household glucometers, whether non-invasive blood suppression or blood pricking, claim to be capable of detecting blood sugar values, can only actually measure electronic data, have a large error between the accuracy and the real blood sugar value, and have an error of more than +/-20% in the accuracy. For example, a true blood glucose value of the user of 6.5, a ± 20% error has caused the measured value to float between 5.2 and 7.8. Such large floating intervals have resulted in some simply hyperglycemic risk groups being misdiagnosed as diabetic patients, or some diabetic patients being misdiagnosed as risk groups, delaying treatment.
Therefore, at present, no non-invasive blood sugar detector which can be used as a real product is available.
It is obvious that the prior art has certain defects.
Disclosure of Invention
The invention aims to solve the technical problem of providing a non-invasive anti-interference blood sugar detector and a method for detecting blood sugar by using the same, which can reduce external interference and capture more accurate data through reasonable design of electrodes and circuits. Meanwhile, a more real blood sugar value is measured in a scientific calibration mode.
In order to achieve the purpose, the invention adopts the following technical scheme:
a non-invasive anti-interference blood sugar detector comprises a first electrode, a second electrode, a third electrode and a fourth electrode which are exposed outside a shell and are composed of conductors; and a working circuit;
the first electrode, the third electrode and the fourth electrode are arranged at one end of the shell to form a first probe, and the second electrode is independently arranged at the other end of the shell to form a second probe; the first electrode is connected with the second electrode and is used for forming a loop by two different positions contacting with a human body so as to measure data; the third electrode is connected with the fourth electrode and is used for contacting the human body at the first probe to form a loop so as to measure interference data at a contact point of the first probe and the human body;
wherein, the working circuit includes:
the signal processing module is used for filtering and adjusting data intercepted by each electrode;
the storage unit is used for storing data of blood drawing detection of a user for first correction;
the microprocessor is used for calculating and processing the data obtained by the signal processing module;
the power supply module is used for supplying power to all the elements;
the first electrode, the second electrode, the third electrode and the fourth electrode are connected with the signal processing module, the microprocessor is connected with the signal processing module, the storage unit is connected with the microprocessor, and the power supply module supplies power to all the elements through a circuit.
Furthermore, the signal processing module comprises a signal filtering circuit, a signal amplifying circuit and a converting circuit; the signal filter circuit and the signal amplification circuit are connected to two loops consisting of a first electrode, a second electrode, a third electrode and a fourth electrode; the conversion circuit is connected with the signal amplification circuit, and the microprocessor is connected with the conversion circuit.
Furthermore, a first capacitor and a second capacitor are connected between the signal filter circuit and the signal amplifying circuit, and are used for storing the signal current formed by the loop into the signal filter circuit after the signal current is filtered and rectified by the signal filter circuit.
Furthermore, the first probe is respectively provided with two middle conductors, and the peripheries of the two middle conductors are respectively provided with an annular conductor which is used as the first electrode, the third electrode and the fourth electrode.
Further, the device also comprises a display unit used for outputting the result of the data processing; the display unit is connected with the microprocessor and exposed out of the shell.
Furthermore, the blood drawing test device also comprises an input unit which is used for inputting the data of the blood drawing test of the user to the storage unit and is connected with the microprocessor.
A non-invasive anti-interference blood sugar detection method comprises the following steps:
s01, enabling the first probe with the electrode and the second probe with the electrode to respectively contact different positions of the human body to form a loop, sending current to the electrode on the first probe, detecting electronic data, calculating and storing the electronic data in a storage unit;
s02, detecting the blood sugar value of the user by adopting a hospital blood drawing detection mode, storing the detected corrected blood sugar value, and matching the data obtained in the step S01 as corrected data with the corrected blood sugar value;
when it is necessary to detect the blood glucose level at S03, step S01 is repeated, and the data measured at that time is compared with the correction data and corrected blood glucose level obtained at step S02 as real-time data, thereby obtaining the real-time blood glucose level of the user at that time.
Further, the step S01 specifically includes:
s011, enabling a first probe with a first electrode, a third electrode and a fourth electrode and a second probe with a second electrode to respectively contact different positions of a human body; the first electrode, the second electrode and the human body form a measuring loop; a deduction loop is formed by the third electrode, the fourth electrode and the human body at the contact point of the first probe;
s012, electrifying the first electrode to emit current I1And passing a current I1Detecting electronic data of the measuring circuit;
s013, electrifying the first electrode to emit current I1While the third electrode is electrified to emit current I2And passing a total current I1+I2Detecting electronic data of the subtraction loop;
s014, the microprocessor processes and calculates the electronic data of the measuring loop and the electronic data of the deducting loop to obtain high-precision data after deducting the contact interference and stores the high-precision data;
further, in steps S012 to S013, the first electrode is energized with the striking current I1And the current I emitted by the first electrode and the third electrode simultaneously1+I2And respectively storing the electric quantity into the first capacitor and the electric quantity into the second capacitor, respectively discharging the electric quantity to take out the electric quantity of the first capacitor and the electric quantity of the second capacitor, and respectively obtaining electronic data of the measuring loop and the deduction loop.
Further, each time steps S011 to S014 are executed, step S012 is repeatedly executed a plurality of times at regular time intervals before step S013, and data with the largest number of times of repetition is taken as electronic data of the measurement circuit.
Further, every time steps S011 to S014 are performed, steps S012 to S014 are repeated several times after stimulating the user at step S01 for 0.8-1.1 seconds, so as to obtain stable and highly accurate electronic data.
Further, before all the steps, there is a preprocessing step S00, which has the following steps,
s001, classifying blood sugar values with different heights according to the severity of the heights of the blood sugar values;
s002, on the basis of standard blood glucose values of different classifications, calculating interval values of the classifications according to positive and negative tolerance, and establishing a database of numerical value intervals of the different classifications;
the instantaneous blood glucose level obtained in step S03 is compared with the database created in step S002, and the state of the user is obtained.
According to the non-invasive anti-interference blood glucose detector provided by the invention, the plurality of electrodes are designed to form the plurality of loops, so that the interference of an external environment in the detection process can be reduced in a data deduction mode, and the detected data is more accurate. And the design of the loop has the functions of signal amplification and signal filtration, so that the sensitivity and the accuracy of data detection are further improved.
The invention further provides a non-invasive anti-interference blood glucose detection method, which adopts a more advanced multi-electrode measurement method, avoids interference and obtains more accurate data. And a scientific data calibration method is provided, so that the true and accurate blood sugar value is matched.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
Fig. 1 is a schematic external structural diagram of a non-invasive anti-interference blood glucose meter according to the present invention.
Fig. 2 is a schematic diagram of an internal circuit structure.
Fig. 3 is a schematic diagram of a circuit formed by the electrodes and the human body.
Description of reference numerals:
1. housing 2, first Probe
3. Second probe 4, first electrode
5. Second electrode 6, third electrode
7. Fourth electrode 8 and display unit
9. Signal processing module 10 and storage unit
11. Microprocessor 12 and power module
13. Signal filter circuit 14 and signal amplifier circuit
15. Switching circuit 16, first capacitor
17. Second capacitor
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention and the accompanying drawings. It should be noted that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example one
Referring to fig. 1 to 2, an embodiment of the present invention provides a non-invasive anti-interference blood glucose monitor, including a first electrode 4, a second electrode 5, a third electrode 6 and a fourth electrode 7, which are exposed outside a housing 1 and are formed by conductors; and a working circuit;
the first electrode 4, the third electrode 6 and the fourth electrode 7 are arranged at one end of the shell 1 to form a first probe 2, and the second electrode 5 is independently arranged at the other end of the shell 1 to form a second probe 3; the first electrode 4 is connected with the second electrode 5 and is used for forming a loop by two different positions contacting with the human body so as to measure data; the third electrode 6 is connected with the fourth electrode 7 and is used for contacting the human body at the first probe 2 to form a loop so as to measure interference data at the contact point of the first probe 2 and the human body;
wherein, the working circuit includes:
the signal processing module 9 is used for filtering and adjusting data intercepted by each electrode;
a storage unit 10 for storing data of blood drawing test of a user for first correction;
a microprocessor 11 for calculating and processing the data obtained by the signal processing module 9;
the power module 12 is used for supplying power to all the elements;
the first electrode 4, the second electrode 5, the third electrode 6 and the fourth electrode 7 are connected with the signal processing module 9, the microprocessor 11 is connected with the signal processing module 9, the storage unit 10 is connected with the microprocessor 11, and the power module 12 supplies power to all the elements through a circuit.
Different from the prior art, the blood glucose data detection device does not detect the blood glucose data by only forming a loop with the human body through two electrodes, but adopts four electrodes distributed on two probes to form a plurality of loops with the human body, so as to realize the deduction operation function of interference data and enable the detection data to be more accurate.
The working principle of each electrode is shown in fig. 3. The four electrodes are respectively arranged on the two probes and contact different positions of the human body, and preferably, the first probe 2 contacts the palm of the human body and the second probe 3 contacts the thumb of the other hand. The first electrode 4 provided on the first probe 2 and the second electrode 5 provided on the second probe 3 form a circuit, and the electronic data can be detected by non-invasive conduction. However, when the probe is in contact with the skin of a human body, the probe is easily affected by external factors such as contact effectiveness of the contact, humidity, foreign matters and the like, so that interference is generated near the contact, and stability and precision of data are affected. Therefore, the third electrode 6 and the fourth electrode 7 are arranged at the first probe 2 to form a loop, and a deduction loop is formed at the contact point of the palm, so that the external interference near the contact point is specially detected and reduced.
In addition to the design of the electrodes, the present invention also provides a memory unit 10 in the circuit for storing the actual blood glucose level measured by the user in a blood drawing manner and the electronic data measured by the electrodes to realize the calibration of the data. Thus, the present invention does not measure electrical signals purely. The specific calibration method will be described in detail in the method for measuring blood glucose hereinafter.
It should be noted that various buttons, switches, etc. may be further installed on the housing 1 to implement various control functions. However, these components are not the technical focus of the present invention, and are not greatly related to the technical solution, and are not described in detail in the present invention. And the structure is omitted in the drawings of the specification.
Preferably, the signal processing module 9 includes a signal filtering circuit 13, a signal amplifying circuit 14 and a converting circuit 15; the signal filter circuit 13 and the signal amplifier circuit 14 are connected to two loops consisting of the first electrode 4, the second electrode 5, the third electrode 6 and the fourth electrode 7; the conversion circuit 15 is connected to the signal amplification circuit 14, and the microprocessor 11 is connected to the conversion circuit 15.
The signal amplifying circuit 14 is used for receiving and amplifying the electrical signals transmitted by the electrodes, so that the weak electrical signals are more sensitive after being amplified. The signal filter circuit 13 is used for rectifying and filtering noise to obtain a clean signal. The conversion circuit 15 is used to convert an analog signal into a digital signal.
Preferably, a first capacitor 16 and a second capacitor 17 are connected between the signal filter circuit 13 and the signal amplifier circuit 14, and are used for storing the signal current formed by the loop after being filtered and rectified by the signal filter circuit 13.
The following configuration is preferably adopted for the distribution and configuration of the electrodes on the first probe 2. The first probe 2 is respectively provided with two middle conductors, and the peripheries of the two middle conductors are provided with an annular conductor which is respectively used as a first electrode 4, a third electrode 6 and a fourth electrode 7.
It should be noted that the first electrode 4, the third electrode 6, or the fourth electrode 7 corresponds to only one of the three conductors, which is not the technical point of the present invention. In general, it is preferable that the third electrode 6 be an annular conductor and the first electrode 4 and the fourth electrode 7 be two intermediate conductors, respectively. However, a ring conductor may be used as the first electrode 4, and two central conductors may be used as the third electrode 6 and the fourth electrode 7, respectively. The three electrodes are arranged on the first probe 2, so that the contact interference is eliminated, and the data acquisition precision is improved. Therefore, the arrangement of the first electrode 4, the third electrode 6 and the fourth electrode 7 is not limited to a large extent without departing from the design purpose.
Preferably, a display unit 8 is further included for outputting the result of the data processing; the display unit 8 is connected to the microprocessor 11 and exposed from the housing 1. The blood drawing test device further comprises an input unit, wherein the input unit is used for inputting data of blood drawing test of a user to the storage unit 10 and is connected with the microprocessor 11.
Of course, it is not excluded that the present invention does not have the display unit 8 per se, and the result is displayed by means of signal transmission to an external display device. Similarly, it is also possible that the present invention does not have an input unit per se, and it is also possible to input data to the storage unit 10 by way of wireless or wired transmission through an external device.
According to the non-invasive anti-interference blood glucose detector provided by the invention, the plurality of electrodes are designed to form the plurality of loops, so that the interference of an external environment in the detection process can be reduced in a data deduction mode, and the detected data is more accurate. And the design of the loop has the functions of signal amplification and signal filtration, so that the sensitivity and the accuracy of data detection are further improved.
Example two
This embodiment details a method for detecting blood glucose with non-invasive interference resistance, which is also the working process of the non-invasive interference-resistant blood glucose detector described in the first embodiment.
A non-invasive anti-interference blood sugar detection method comprises the following steps:
s01, enabling the first probe with the electrode and the second probe with the electrode to respectively contact different positions of the human body to form a loop, sending current to the electrode on the first probe, detecting electronic data, calculating and storing the electronic data in a storage unit;
s02, detecting the blood sugar value of the user by adopting a hospital blood drawing detection mode, storing the detected corrected blood sugar value, and matching the data obtained in the step S01 as corrected data with the corrected blood sugar value;
when it is necessary to detect the blood glucose level at S03, step S01 is repeated, and the data measured at that time is compared with the correction data and corrected blood glucose level obtained at step S02 as real-time data, thereby obtaining the real-time blood glucose level of the user at that time.
The method advocates the calibration matching calculation with the actual blood sugar value measured by blood drawing, so that the blood sugar value is detected not only by a simple electronic data but also by a value really matched with the blood sugar value of a human body. The method is scientific and reasonable, has high precision, is beneficial to accurately judging the blood sugar condition of the user, and does not delay diagnosis and treatment.
As described above, simply intercepting the electronic data itself does not have a substantial effect on blood glucose detection and does not obtain a true blood glucose level. Therefore, the present invention designs a calibration procedure, i.e. step S02 is performed, and the actual blood glucose level of the user is measured by going to the hospital for blood drawing test and is inputted into the blood glucose meter. Before the blood glucose data is input, the high-precision electronic data is intercepted through normal electrode non-invasive detection, and the electronic data can be matched with the real blood glucose value measured in the step S02, so that calibration is realized. The process is actually a learning process of the blood sugar detector aiming at the actual physical condition of the user. Through calibration, a data matching system can be constructed, and blood sugar values corresponding to different electronic data can be known. Even, a database can be established to match the corresponding blood sugar value and inform the user of the physical state.
It is generally recommended that calibration be performed at intervals in order to maintain data accuracy, since changes in blood glucose values vary over time and the body state varies. For diabetic patients, 1.5-3 months is a treatment course generally, so that the calibration of blood-drawing blood-sugar detection at intervals is scientific and reasonable.
The process of blood drawing, blood sugar value detection and blood sugar value calibration is an important technical breakthrough of the method. The electronic data detected by the electronic method is only one set of electronic data, not the true blood glucose level data, even if the accuracy is higher. Even the household blood sampling type blood glucose meter widely adopted at present is easily influenced by factors such as impurities, blood concentration, whether the blood sufficiently reacts in the meter and the like, and the blood glucose value is distorted. Only when the method of blood sugar value detection by blood drawing in a hospital is adopted, the real blood sugar value is obtained for comparison and calibration, and the blood sugar value measured by the instrument is accurate.
For example, the current value is 100 ma out of the electronic data measured before, and the blood glucose level corresponding to the electronic data is known. In the electronic data measured after that, the current value became 150 ma. The microprocessor 11 writes a formula for calculating the blood glucose level, and the current blood glucose level can be calculated by the formula.
Specifically, the step S01 further specifically includes:
s011, enabling the first probe 2 with the first electrode 4, the third electrode 6 and the fourth electrode 7 and the second probe 3 with the second electrode 5 to respectively contact different positions of a human body; the first electrode 4 and the second electrode 5 form a measuring loop with the human body; a deduction loop is formed by the third electrode 6, the fourth electrode 7 and the human body at the contact point of the first probe 2;
s012, electrifying the first electrode 4 to emit current I1And passing a current I1Detecting electronic data of the measuring circuit;
s013, passing current 11 to the first electrode 4 and passing current I to the third electrode 62And passing a total current I1+I2Detecting electronic data of the subtraction loop;
s014, the microprocessor 11 processes and calculates the electronic data of the measuring loop and the electronic data of the deducting loop to obtain and store the high-precision data after deducting the contact interference;
in the above steps, steps S011 to S014 are actually steps of implementing non-invasive electrode detection by using a blood glucose detector, which specifically describes a process of intercepting data by electrifying four electrodes and a method for reducing external interference. The routine process of detecting blood sugar by using the blood sugar detector is the process of repeating step S01.
More specifically, in steps S012 to S013, the first electrode 4 is energized with the striking current I1And the current I emitted by the first electrode 4 and the third electrode 6 simultaneously1+I2And the electric quantity is respectively stored in the first capacitor 16 and the second capacitor 17, and then the electric quantity of the first capacitor 16 and the electric quantity of the second capacitor 17 are respectively discharged and taken out, so that the electronic data of the measuring loop and the deduction loop are respectively obtained.
And repeatedly intercepting data in certain steps every time the non-invasive detection of the electrode is carried out, and selecting effective data for calculation so as to further improve the accuracy of the detected data. Preferably, each time steps S011 to S014 are executed, step S012 is repeatedly executed a plurality of times at regular time intervals before step S013, and data with the largest number of times of repetition is taken as electronic data of the measurement circuit.
For example, the first electrode 4 emits a minute current I every 0.1 second1The third electrode 6 emits a tiny current I every 0.5 seconds to the human body2To the human body. The first electrode 4 is subjected to the current-energization detection a plurality of times (i.e., the step S02 is repeatedly performed a plurality of times) before 0.5 seconds, and data in which the number of times of repetition is the largest can be grasped as electronic data of the measurement circuit. When the current is simultaneously applied to the first electrode 4 and the third electrode 6 in 0.5 second, the current value used in calculation is I1+I2And (4) summing.
Experiments show that after the first probe 2 is contacted with the contact point of the human body, the power can not be switched on to obtain stable electronic data immediately, but the data tend to be stable after stimulating the user for a certain time. Therefore, it is preferable to perform steps S012 to S014 after stimulating the user for 0.8 to 1.1 seconds at step S011 every time steps S011 to S014 are performed, which is advantageous in obtaining stable electronic data.
Furthermore, besides waiting for the data to be stable, effective data can be obtained by repeatedly intercepting the data for a plurality of times after the electrode is contacted with the contact of the human body. Preferably, steps S012 to S014 are repeatedly executed a plurality of times each time steps S011 to S014 are executed, and high-precision data having the largest number of times of repetition is acquired.
For example, stable data appears at 0.8-1.1 seconds after the electrode is in contact with the human body's contact. Then the data interception is carried out in the interval of 0.8-1.1 seconds, and the interception of a plurality of data in the time interval is restarted for a plurality of times, and the valid data is captured.
As a further improvement of the determination calculation method, there may be a preprocessing step S00, which has the following steps,
s001, classifying blood sugar values with different heights according to the severity of the heights of the blood sugar values;
s002, on the basis of standard blood glucose values of different classifications, calculating interval values of the classifications according to positive and negative tolerance, and establishing a database of numerical value intervals of the different classifications;
the instantaneous blood glucose level obtained in step S03 is compared with the database created in step S002, and the state of the user is obtained.
For example, the severity of the high or low blood glucose level can be roughly classified into:
the optional volume difference is +/-10%, and the interval value is determined as follows:
| status of state | Interval of blood sugar level |
| Is normal | 4.9-5.9 |
| Danger group | 5.9-7.2 |
| Diabetes mellitus type II | 9.7-11.9 |
| Diabetes mellitus type I | 14.6-17.8 |
The instant blood sugar value measured in step S03 can be directly compared with the blood sugar value interval, and the user can know the state at once, so that the physician can track the treatment and adjust the medication conveniently. Because the electronic signal is weak, each person has a difference in the electronic response, and the accuracy is approached by locking the type of the user and reducing the range with a certain percentage of probability error.
The distribution of the numerical intervals described above is merely an application example, and even if the distribution of the numerical intervals is different or further subdivided, the idea of the present invention is included.
The non-invasive anti-interference blood glucose detection method provided by the invention adopts a more advanced multi-electrode measurement method, avoids interference and obtains more accurate data. And a scientific data calibration method is provided, so that the true and accurate blood sugar value is matched.
The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the present invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.
Claims (12)
1. A non-invasive anti-interference blood glucose detector is characterized in that: the device comprises a first electrode, a second electrode, a third electrode and a fourth electrode which are exposed outside a shell and are composed of conductors; and a working circuit;
the first electrode, the third electrode and the fourth electrode are arranged at one end of the shell to form a first probe, and the second electrode is independently arranged at the other end of the shell to form a second probe; the first electrode is connected with the second electrode and is used for forming a loop by two different positions contacting with a human body so as to measure data; the third electrode is connected with the fourth electrode and is used for contacting the human body at the first probe to form a loop so as to measure interference data at a contact point of the first probe and the human body;
wherein, the working circuit includes:
the signal processing module is used for filtering and adjusting data intercepted by each electrode;
the storage unit is used for storing data of blood drawing detection of a user for first correction;
the microprocessor is used for calculating and processing the data obtained by the signal processing module;
the power supply module is used for supplying power to all the elements;
the first electrode, the second electrode, the third electrode and the fourth electrode are connected with the signal processing module, the microprocessor is connected with the signal processing module, the storage unit is connected with the microprocessor, and the power supply module supplies power to all the elements through a circuit.
2. The non-invasive interference-free blood glucose monitor according to claim 1, wherein: the signal processing module comprises a signal filter circuit, a signal amplifying circuit and a conversion circuit; the signal filter circuit and the signal amplification circuit are connected to two loops consisting of a first electrode, a second electrode, a third electrode and a fourth electrode; the conversion circuit is connected with the signal amplification circuit, and the microprocessor is connected with the conversion circuit.
3. The non-invasive interference-free blood glucose monitor according to claim 2, wherein: and a first capacitor and a second capacitor are connected between the signal filter circuit and the signal amplifying circuit and used for storing the signal current formed by the loop into the signal filter circuit after the signal current is filtered and rectified by the signal filter circuit.
4. The non-invasive interference-free blood glucose monitor according to claim 1, wherein: the first probe is respectively provided with two middle conductors, and the peripheries of the two middle conductors are provided with an annular conductor which is respectively used as a first electrode, a third electrode and a fourth electrode.
5. The non-invasive interference-free blood glucose monitor according to claim 1, wherein: the display unit is used for outputting the result of the data processing; the display unit is connected with the microprocessor and exposed out of the shell.
6. The non-invasive interference-free blood glucose monitor according to claim 1, wherein: the blood drawing detection device also comprises an input unit which is used for inputting the data of the blood drawing detection of the user to the storage unit, and the input unit is connected with the microprocessor.
7. A non-invasive anti-interference blood sugar detection method is characterized in that: the method comprises the following steps:
s01, enabling the first probe with the electrode and the second probe with the electrode to respectively contact different positions of the human body to form a loop, sending current to the electrode on the first probe, detecting electronic data, calculating and storing the electronic data in a storage unit;
s02, detecting the blood sugar value of the user by adopting a hospital blood drawing detection mode, storing the detected corrected blood sugar value, and matching the data obtained in the step S01 as corrected data with the corrected blood sugar value;
when it is necessary to detect the blood glucose level at S03, step S01 is repeated, and the data measured at that time is compared with the correction data and corrected blood glucose level obtained at step S02 as real-time data, thereby obtaining the real-time blood glucose level of the user at that time.
8. The non-invasive, interference-free, blood glucose detection method according to claim 7, wherein the step S01 specifically includes:
s011, enabling a first probe with a first electrode, a third electrode and a fourth electrode and a second probe with a second electrode to respectively contact different positions of a human body; the first electrode, the second electrode and the human body form a measuring loop; a deduction loop is formed by the third electrode, the fourth electrode and the human body at the contact point of the first probe;
s012, electrifying the first electrode to emit current I1And passing a current I1Detecting electronic data of the measuring circuit;
s013, electrifying the first electrode to emit current I1At the same time, a current l is applied to the third electrode2And passing a total current l1+l2Detecting electronic data of the subtraction loop;
and S014, the microprocessor processes and calculates the electronic data of the measuring loop and the electronic data of the deducting loop to obtain and store the high-precision data after deducting the contact interference.
9. The non-invasive, tamper-resistant, method of detecting blood glucose according to claim 8, wherein: in step S012S013, the first electrode is energized with the emitted current I1And the current I emitted by the first electrode and the third electrode simultaneously1+I2And respectively storing the electric quantity into the first capacitor and the electric quantity into the second capacitor, respectively discharging the electric quantity to take out the electric quantity of the first capacitor and the electric quantity of the second capacitor, and respectively obtaining electronic data of the measuring loop and the deduction loop.
10. The non-invasive, tamper-resistant, method of detecting blood glucose according to claim 8, wherein: each time steps S011 to S014 are executed, step S012 is repeatedly executed a plurality of times at regular time intervals before step S013, and data with the largest number of times of repetition is taken as electronic data of the measurement circuit.
11. The method of claim 8 or 10, wherein the method further comprises: each time steps S011 to S014 are executed, steps S012 to S014 are repeated several times after stimulating the user at step S01 for 0.8-1.1 seconds to obtain stable and highly accurate electronic data.
12. The non-invasive, tamper-resistant, method of detecting blood glucose according to claim 7, wherein:
before all the steps, there is a preprocessing step S00, which has the steps,
s001, classifying blood sugar values with different heights according to the severity of the heights of the blood sugar values;
s002, on the basis of standard blood glucose values of different classifications, calculating interval values of the classifications according to positive and negative tolerance, and establishing a database of numerical value intervals of the different classifications;
the instantaneous blood glucose level obtained in step S03 is compared with the database created in step S002, and the state of the user is obtained.
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| CN201811553156.7A CN111329490A (en) | 2018-12-18 | 2018-12-18 | Non-invasive anti-interference blood glucose detector and method for detecting blood glucose by using same |
| PCT/CN2018/124207 WO2020124658A1 (en) | 2018-12-18 | 2018-12-27 | Non-invasive anti-interference blood glucose measuring instrument and blood glucose measuring method therefor |
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